JPS4843509B2 - - Google Patents
Info
- Publication number
- JPS4843509B2 JPS4843509B2 JP46064812A JP6481271A JPS4843509B2 JP S4843509 B2 JPS4843509 B2 JP S4843509B2 JP 46064812 A JP46064812 A JP 46064812A JP 6481271 A JP6481271 A JP 6481271A JP S4843509 B2 JPS4843509 B2 JP S4843509B2
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6859170A | 1970-08-31 | 1970-08-31 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS475678A JPS475678A (show.php) | 1972-03-25 |
| JPS4843509B2 true JPS4843509B2 (show.php) | 1973-12-19 |
Family
ID=22083517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP46064812A Expired JPS4843509B2 (show.php) | 1970-08-31 | 1971-08-26 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3745162A (show.php) |
| JP (1) | JPS4843509B2 (show.php) |
| AU (1) | AU448869B2 (show.php) |
| CA (1) | CA934378A (show.php) |
| CH (1) | CH529137A (show.php) |
| DE (1) | DE2143589A1 (show.php) |
| ES (1) | ES394541A1 (show.php) |
| FR (1) | FR2103641B1 (show.php) |
| GB (1) | GB1331710A (show.php) |
| ZA (1) | ZA715769B (show.php) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2012039448A1 (ja) * | 2010-09-24 | 2014-02-03 | 株式会社キラルジェン | 不斉補助基 |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3947456A (en) * | 1970-01-06 | 1976-03-30 | Hoffman-La Roche Inc. | Substituted 4-phenyl isoquinolines |
| US3872125A (en) * | 1973-03-03 | 1975-03-18 | Sandoz Ag | 3-substituted-4-aryl isoquinolines |
| US3910915A (en) * | 1973-07-23 | 1975-10-07 | Searle & Co | 1-Aryl-2-{8 (substituted amino)alkanoyl{9 -1,2,3,4-tetrahydroisoquinolines |
| US3870722A (en) * | 1973-11-02 | 1975-03-11 | Sandoz Ag | 2-Methyl-3-substituted-4-aryl isoquinolines |
| GB1463667A (en) * | 1973-12-17 | 1977-02-02 | Wyeth John & Brother Ltd | Process for preparing thioamides |
| US4092418A (en) * | 1974-03-05 | 1978-05-30 | John Wyeth & Brother Limited | Certain 1-carbothioamides of 1,5-naphthyridine derivatives |
| US4092320A (en) * | 1974-03-05 | 1978-05-30 | John Wyeth & Brother Limited | Certain 1-(N-acyl)-carbothioamides of 1,5-naphthyridine derivatives |
| US4410699A (en) * | 1981-08-07 | 1983-10-18 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted 1,2,3,4-tetrahydro-4-isoquinolinols |
| ES2616051T3 (es) | 2008-12-02 | 2017-06-09 | Wave Life Sciences Japan, Inc. | Método para la síntesis de ácidos nucleicos modificados en el átomo de fósforo |
| CA2767253A1 (en) | 2009-07-06 | 2011-01-13 | Ontorii, Inc. | Novel nucleic acid prodrugs and methods of use thereof |
| JP6128529B2 (ja) | 2011-07-19 | 2017-05-17 | ウェイブ ライフ サイエンシズ リミテッドＷａｖｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｌｔｄ． | 官能化核酸の合成のための方法 |
| US9982257B2 (en) | 2012-07-13 | 2018-05-29 | Wave Life Sciences Ltd. | Chiral control |
| MX356830B (es) | 2012-07-13 | 2018-06-15 | Shin Nippon Biomedical Laboratories Ltd | Adyuvante de acido nucleico quiral. |
| US9598458B2 (en) | 2012-07-13 | 2017-03-21 | Wave Life Sciences Japan, Inc. | Asymmetric auxiliary group |
| US10144933B2 (en) | 2014-01-15 | 2018-12-04 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having immunity induction activity, and immunity induction activator |
| WO2015108046A1 (ja) | 2014-01-15 | 2015-07-23 | 株式会社新日本科学 | 抗アレルギー作用を有するキラル核酸アジュバンド及び抗アレルギー剤 |
| EP3095459A4 (en) | 2014-01-15 | 2017-08-23 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having antitumor effect and antitumor agent |
| DK3094728T3 (da) | 2014-01-16 | 2022-05-16 | Wave Life Sciences Ltd | Kiralt design |
-
1970
- 1970-08-31 US US00068591A patent/US3745162A/en not_active Expired - Lifetime
-
1971
- 1971-08-25 AU AU32712/71A patent/AU448869B2/en not_active Expired
- 1971-08-25 GB GB3994471A patent/GB1331710A/en not_active Expired
- 1971-08-26 JP JP46064812A patent/JPS4843509B2/ja not_active Expired
- 1971-08-26 ES ES394541A patent/ES394541A1/es not_active Expired
- 1971-08-30 CH CH1269271A patent/CH529137A/fr not_active IP Right Cessation
- 1971-08-30 FR FR7131357A patent/FR2103641B1/fr not_active Expired
- 1971-08-30 CA CA121716A patent/CA934378A/en not_active Expired
- 1971-08-30 ZA ZA715769A patent/ZA715769B/xx unknown
- 1971-08-31 DE DE19712143589 patent/DE2143589A1/de active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2012039448A1 (ja) * | 2010-09-24 | 2014-02-03 | 株式会社キラルジェン | 不斉補助基 |
| JP2016128431A (ja) * | 2010-09-24 | 2016-07-14 | 株式会社Ｗａｖｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｊａｐａｎ | 不斉補助基 |
Also Published As
| Publication number | Publication date |
|---|---|
| GB1331710A (en) | 1973-09-26 |
| CH529137A (fr) | 1972-10-15 |
| JPS475678A (show.php) | 1972-03-25 |
| DE2143589A1 (de) | 1972-03-09 |
| US3745162A (en) | 1973-07-10 |
| AU3271271A (en) | 1973-03-01 |
| CA934378A (en) | 1973-09-25 |
| AU448869B2 (en) | 1974-05-30 |
| ES394541A1 (es) | 1974-10-16 |
| ZA715769B (en) | 1972-04-26 |
| FR2103641A1 (show.php) | 1972-04-14 |
| FR2103641B1 (show.php) | 1974-10-18 |