JPH11511113A5 - - Google Patents
Info
- Publication number
- JPH11511113A5 JPH11511113A5 JP1996531337A JP53133796A JPH11511113A5 JP H11511113 A5 JPH11511113 A5 JP H11511113A5 JP 1996531337 A JP1996531337 A JP 1996531337A JP 53133796 A JP53133796 A JP 53133796A JP H11511113 A5 JPH11511113 A5 JP H11511113A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9516943.9A GB9516943D0 (en) | 1995-08-18 | 1995-08-18 | Novel cyclopropylindoles and their secoprecursors,and their use as prodrugs |
| GB9516943.9 | 1995-08-18 | ||
| PCT/NZ1996/000083 WO1997007097A1 (en) | 1995-08-18 | 1996-08-19 | Cyclopropylindoles and their seco precursors, and their use as prodrugs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH11511113A JPH11511113A (ja) | 1999-09-28 |
| JPH11511113A5 true JPH11511113A5 (https=) | 2004-07-22 |
Family
ID=10779431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8531337A Withdrawn JPH11511113A (ja) | 1995-08-18 | 1996-08-19 | シクロプロピルインドール類およびそのセコ前駆体、ならびにプロドラッグとしてのこれらの使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5985909A (https=) |
| EP (1) | EP0850220A1 (https=) |
| JP (1) | JPH11511113A (https=) |
| AU (1) | AU707644B2 (https=) |
| CA (1) | CA2229264A1 (https=) |
| GB (1) | GB9516943D0 (https=) |
| NZ (1) | NZ315410A (https=) |
| WO (1) | WO1997007097A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6130237A (en) * | 1996-09-12 | 2000-10-10 | Cancer Research Campaign Technology Limited | Condensed N-aclyindoles as antitumor agents |
| AU721037B2 (en) * | 1996-09-12 | 2000-06-22 | Auckland Uniservices Limited | Condensed N-acylindoles as antitumor agents |
| GB9712370D0 (en) * | 1997-06-14 | 1997-08-13 | Aepact Ltd | Therapeutic systems |
| EP0887348A1 (en) * | 1997-06-25 | 1998-12-30 | Boehringer Mannheim Italia S.p.A. | Bis-Indole derivatives having antimetastatic activity, a process for their preparation and pharmaceutical compositions containing them |
| US6410584B1 (en) * | 1998-01-14 | 2002-06-25 | Cell Pathways, Inc. | Method for inhibiting neoplastic cells with indole derivatives |
| DE69925133T2 (de) | 1998-08-27 | 2006-01-19 | Spirogen Ltd., Ryde | Pyrrolobenzodiazepine |
| GB9818730D0 (en) | 1998-08-27 | 1998-10-21 | Univ Portsmouth | Collections of compounds |
| US6909006B1 (en) | 1999-08-27 | 2005-06-21 | Spirogen Limited | Cyclopropylindole derivatives |
| KR20120068769A (ko) | 2002-07-15 | 2012-06-27 | 더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 | 음이온성 인지질 및 아미노인지질에 결합하는 선택된 항체 및 치료하는데 있어서 이의 용도 |
| GB0226593D0 (en) | 2002-11-14 | 2002-12-24 | Consultants Ltd | Compounds |
| ZA200507752B (en) | 2003-03-28 | 2007-01-31 | Threshold Pharmaceuticals Inc | Compositions and methods for treating cancer |
| GB0321295D0 (en) | 2003-09-11 | 2003-10-15 | Spirogen Ltd | Synthesis of protected pyrrolobenzodiazepines |
| EP1896040B1 (en) | 2005-06-29 | 2012-08-01 | Threshold Pharmaceuticals, Inc. | Phosphoramidate alkylator prodrugs |
| US8940784B2 (en) * | 2006-02-02 | 2015-01-27 | Syntarga B.V. | Water-soluble CC-1065 analogs and their conjugates |
| GB0619325D0 (en) * | 2006-09-30 | 2006-11-08 | Univ Strathclyde | New compounds |
| ES2884044T3 (es) * | 2006-12-26 | 2021-12-10 | Immunogenesis Inc | Profármaco alquilante de fosforamidato para el tratamiento del cáncer |
| US9901567B2 (en) | 2007-08-01 | 2018-02-27 | Syntarga B.V. | Substituted CC-1065 analogs and their conjugates |
| US20090118031A1 (en) * | 2007-11-01 | 2009-05-07 | Qualizza Gregory K | Shaft Structure with Configurable Bending Profile |
| CA2705152C (en) | 2007-11-09 | 2016-10-11 | Peregrine Pharmaceuticals, Inc. | Anti-vegf antibody compositions and methods |
| UY31506A1 (es) * | 2007-12-03 | 2009-08-03 | Derivados de indolinona y procedimiento para su preparacion | |
| ES2647317T3 (es) | 2008-11-03 | 2017-12-20 | Syntarga B.V. | Análogos de CC-1065 y sus conjugados |
| PT3056203T (pt) | 2010-04-21 | 2018-02-15 | Syntarga Bv | Conjugados de análogos de cc-1065 e ligantes bifuncionais |
| US9056874B2 (en) | 2012-05-04 | 2015-06-16 | Novartis Ag | Complement pathway modulators and uses thereof |
| US9475806B2 (en) | 2013-03-14 | 2016-10-25 | Novartis Ag | Complement factor B inhibitors and uses there of |
| CN105849090A (zh) | 2013-10-30 | 2016-08-10 | 诺华股份有限公司 | 2-苄基-苯并咪唑补体因子b抑制剂及其用途 |
| RU2680404C2 (ru) | 2014-01-10 | 2019-02-21 | Синтон Байофармасьютикалс Б. В. | Способ очистки cys-связанных конъюгатов антитело-лекарственное средство |
| BR112023018676A2 (pt) | 2021-03-18 | 2023-10-10 | Seagen Inc | Conjugado anticorpo-fármaco, composição farmacêutica, métodos de tratamento de uma doença ou condição e de um câncer, e, composição de conjugado ligante-fármaco |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3750612T2 (de) * | 1986-12-19 | 1995-03-02 | Upjohn Co | Cc-1065 analoge. |
| GB8705477D0 (en) * | 1987-03-09 | 1987-04-15 | Carlton Med Prod | Drug delivery systems |
| GB8919607D0 (en) * | 1989-08-30 | 1989-10-11 | Wellcome Found | Novel entities for cancer therapy |
| CA2078118C (en) * | 1990-04-25 | 1999-11-16 | Paul A. Aristoff | Cc-1065 analogs |
| CA2122036C (en) * | 1991-10-23 | 2002-09-17 | Gillian Anlezark | Bacterial nitroreductase for the reduction of cb 1954 and analogues thereof to a cytotoxic form |
| NZ240785A (en) * | 1991-11-28 | 1995-08-28 | Cancer Res Campaign Tech | Substituted nitro aniline derivatives and medicaments |
| GB9314960D0 (en) * | 1992-07-23 | 1993-09-01 | Zeneca Ltd | Chemical compounds |
| GB9323008D0 (en) * | 1993-11-05 | 1994-01-05 | Connors Thomas | Improvements relating to cancer therapy |
-
1995
- 1995-08-18 GB GBGB9516943.9A patent/GB9516943D0/en active Pending
-
1996
- 1996-08-19 WO PCT/NZ1996/000083 patent/WO1997007097A1/en not_active Ceased
- 1996-08-19 CA CA002229264A patent/CA2229264A1/en not_active Abandoned
- 1996-08-19 NZ NZ315410A patent/NZ315410A/xx unknown
- 1996-08-19 US US09/011,883 patent/US5985909A/en not_active Expired - Fee Related
- 1996-08-19 EP EP96927217A patent/EP0850220A1/en not_active Withdrawn
- 1996-08-19 AU AU67109/96A patent/AU707644B2/en not_active Ceased
- 1996-08-19 JP JP8531337A patent/JPH11511113A/ja not_active Withdrawn