JPH11506858A - 分析的分離プロセスから生じたデータの分析のための逆畳み込み方法 - Google Patents
分析的分離プロセスから生じたデータの分析のための逆畳み込み方法Info
- Publication number
- JPH11506858A JPH11506858A JP9522836A JP52283697A JPH11506858A JP H11506858 A JPH11506858 A JP H11506858A JP 9522836 A JP9522836 A JP 9522836A JP 52283697 A JP52283697 A JP 52283697A JP H11506858 A JPH11506858 A JP H11506858A
- Authority
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- Prior art keywords
- signal
- fourier transform
- value
- result
- point spread
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F18/00—Pattern recognition
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8603—Signal analysis with integration or differentiation
- G01N30/8617—Filtering, e.g. Fourier filtering
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F2218/00—Aspects of pattern recognition specially adapted for signal processing
- G06F2218/02—Preprocessing
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- Engineering & Computer Science (AREA)
- Theoretical Computer Science (AREA)
- Bioinformatics & Computational Biology (AREA)
- General Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Data Mining & Analysis (AREA)
- Evolutionary Biology (AREA)
- Evolutionary Computation (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Artificial Intelligence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Complex Calculations (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Image Analysis (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.分離プロセスから得られる複数のオーバーラップするサンプルゾーンを含む 信号中のサンプルゾーンを識別するための、信号プロセッサにおける信号処理方 法であって、 分析的分離プロセスの結果を監視する検出器によって生成された信号であって 、複数の部分的に分離されたサンプルゾーンを表している信号を受け取るステッ プと、 該信号の点広がり関数を決定するステップと、 フーリエ変換を用いて該信号および該点広がり関数を時間領域表現から周波数 領域表現に変換するステップと、 該信号のノイズ成分を決定するステップと、 D(f)は該信号のフーリエ変換であり、P(f)は該点広がり関数のフーリエ変 換であり、P*(f)はP(f)の複素共役であり、nは該信号の該ノイズ成分である 下式 を用いて結果信号A(f)の値を計算するステップと、 逆フーリエ変換を用いて該結果信号A(f)を周波数領域表現から時間領域表現 に変換するステップと、 を包含する方法。 2.前記点広がり関数は標準偏差σを有するガウス関数である、請求項1に記載 の方法。 3.σは、定数項αおよび定数項βを含むαβトラッカを用いて決定される、請 求項2に記載の方法。 4.αの値は0.2から0.8の間である、請求項3に記載の方法。 5.αの値は0.4から0.6の間である、請求項3に記載の方法。 6. である、請求項3に記載の方法。 7. である、請求項2に記載の方法。 8.分離プロセスから得られる複数のオーバーラップするサンプルゾーンを含む 信号中のサンプルゾーンを識別するための、信号プロセッサにおける信号処理方 法であって、 分析的分離プロセスの結果を監視する検出器によって生成された信号であって 、部分的に分離されたサンプルゾーンの分布を表している信号を受け取るステッ プと、 該信号の複数の可能な点広がり関数を得るステップと、 該信号および該点広がり関数の各々を、それぞれのフーリエ変換を取ることに より時間領域表現から周波数領域表現に変換するステップと、 該信号のノイズ成分の評価値を得るステップと、 D(f)は該信号のフーリエ変換であり、P(f)は各点広がり関数のフーリエ変 換であり、P*(f)はP(f)の複素共役であり、nは該信号の該ノイズ成分である 下式 を用いて各点広がり関数の結果信号A(f)の値を計算するステップと、 該点広がり関数の各値について、該結果信号A(f)の逆フーリエ変換を取るこ とにより該結果信号を周波数領域から時間領域に変換し、時間領域における結果 信号A(t)を得るステップと、 該結果信号A(t)の負でない値を与える該点広がり関数の最大値を用いて計算 された、該時間領域における結果信号A(t)を報告するステップと、 を包含する方法。 9.複数の部分的に分離されたサンプルゾーンを表している信号から得られるサ ンプルゾーンを識別するための方法ステップを行う機械によって実行可能な命令 のプログラムの実現物としての、機械によって読み出し可能なプログラム記憶装 置であって、該方法ステップは、 分析的分離プロセスの結果を監視する検出器によって生成された信号であって 、複数の部分的に分離されたサンプルゾーンを表している信号を受け取るステッ プと、 該信号の点広がり関数を決定するステップと、 該信号および該点広がり関数を、それぞれのフーリエ変換を取ることにより時 間領域表現から周波数領域表現に変換するステップと、 該信号のノイズ成分を決定するステップと、 D(f)は該信号のフーリエ変換であり、P(f)は該点広がり関数のフーリエ変 換であり、P*(f)はP(f)の複素共役(complex conjugate)であり、nは該信号の 該ノイズ成分である下式 を用いて結果信号A(f)の値を計算するステップと、 該結果信号の逆フーリエ変換を取ることにより、該結果信号A(f)を周波数領 域表現から時間領域表現に変換するステップと、 を包含する、プログラム記憶装置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/579,204 | 1995-12-20 | ||
US08/579,204 US5748491A (en) | 1995-12-20 | 1995-12-20 | Deconvolution method for the analysis of data resulting from analytical separation processes |
PCT/US1996/019242 WO1997022942A1 (en) | 1995-12-20 | 1996-12-02 | Deconvolution method for the analysis of data resulting from analytical separation processes |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH11506858A true JPH11506858A (ja) | 1999-06-15 |
JP3555686B2 JP3555686B2 (ja) | 2004-08-18 |
Family
ID=24315982
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP52283697A Expired - Fee Related JP3555686B2 (ja) | 1995-12-20 | 1996-12-02 | 分析的分離プロセスから生じたデータの分析のための逆畳み込み方法 |
Country Status (8)
Country | Link |
---|---|
US (1) | US5748491A (ja) |
EP (1) | EP0868702B1 (ja) |
JP (1) | JP3555686B2 (ja) |
AT (1) | ATE215245T1 (ja) |
AU (1) | AU702262B2 (ja) |
CA (1) | CA2240539C (ja) |
DE (1) | DE69620232T2 (ja) |
WO (1) | WO1997022942A1 (ja) |
Families Citing this family (34)
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US5985120A (en) * | 1997-06-12 | 1999-11-16 | University Of Massachusetts | Rapid analysis of analyte solutions |
JP3498706B2 (ja) * | 2001-01-05 | 2004-02-16 | 株式会社島津製作所 | 核酸の塩基配列決定方法 |
US7065256B2 (en) * | 2001-02-08 | 2006-06-20 | Dblur Technologies Ltd. | Method for processing a digital image |
WO2003006692A1 (en) | 2001-07-11 | 2003-01-23 | Applera Corporation | Internal calibration standards for electrophoretic analyses |
CA2400601A1 (en) * | 2001-08-31 | 2003-02-28 | University Of Utah Research Foundation | Real-time gene quantification with internal standards |
US7016805B2 (en) * | 2001-12-14 | 2006-03-21 | Wavecrest Corporation | Method and apparatus for analyzing a distribution |
SE0201249D0 (sv) * | 2002-04-22 | 2002-04-22 | Karolinska Innovations Ab | Methods and Arrangements for biological imaging |
US20100266177A1 (en) * | 2002-05-07 | 2010-10-21 | Applied Biosystems, Llc | Signal processing by iterative deconvolution of time series data |
US7627193B2 (en) * | 2003-01-16 | 2009-12-01 | Tessera International, Inc. | Camera with image enhancement functions |
US7773316B2 (en) * | 2003-01-16 | 2010-08-10 | Tessera International, Inc. | Optics for an extended depth of field |
US8294999B2 (en) | 2003-01-16 | 2012-10-23 | DigitalOptics Corporation International | Optics for an extended depth of field |
US20070236573A1 (en) * | 2006-03-31 | 2007-10-11 | D-Blur Technologies Ltd. | Combined design of optical and image processing elements |
US20070239417A1 (en) * | 2006-03-31 | 2007-10-11 | D-Blur Technologies Ltd. | Camera performance simulation |
US20070236574A1 (en) * | 2006-03-31 | 2007-10-11 | D-Blur Technologies Ltd. | Digital filtering with noise gain limit |
US7731826B2 (en) * | 2006-08-17 | 2010-06-08 | Electronic Bio Sciences, Llc | Controlled translocation of a polymer in an electrolytic sensing system |
US8020428B2 (en) * | 2007-04-04 | 2011-09-20 | Colorado School Of Mines | System for and method of monitoring properties of a fluid flowing through a pipe |
WO2009048500A2 (en) * | 2007-08-30 | 2009-04-16 | Shotspotter, Inc. | Processing impulses including bullet pulses and/or muzzle pulses in association with time domain representations |
WO2009108914A1 (en) * | 2008-02-28 | 2009-09-03 | Electronic Bio Sciences, Llc | System and method to improve sequencing accuracy of a polymer |
US8105237B2 (en) * | 2008-05-30 | 2012-01-31 | Volcano Corporation | System and method for characterizing tissue based upon homomorphic deconvolution of backscattered ultrasound |
WO2010117470A2 (en) | 2009-04-10 | 2010-10-14 | Pacific Biosciences Of California, Inc. | Nanopore sequencing devices and methods |
US8652779B2 (en) | 2010-04-09 | 2014-02-18 | Pacific Biosciences Of California, Inc. | Nanopore sequencing using charge blockade labels |
US9058656B2 (en) * | 2012-01-23 | 2015-06-16 | Eiffel Medtech Inc. | Image restoration system and method |
KR101804215B1 (ko) | 2012-03-06 | 2017-12-05 | 삼성전자주식회사 | 강건하게 비균일 모션 블러를 추정하는 방법 및 장치 |
US9640374B2 (en) * | 2012-03-09 | 2017-05-02 | Torion Technologies, Inc. | Deconvolution and identification algorithms for use on spectroscopic data |
US9235931B2 (en) * | 2012-05-18 | 2016-01-12 | Eiffel Medtech Inc. | Method and system for the three-dimensional reconstruction of structures |
US10912476B2 (en) | 2013-01-16 | 2021-02-09 | University Of Vermont | Catheters, systems, and related methods for mapping, minimizing, and treating cardiac fibrillation |
US8880158B2 (en) | 2013-01-16 | 2014-11-04 | University Of Vermont | Methods and systems for determining spatiotemporal variability for mapping cardiac fibrillation |
US10302592B2 (en) * | 2013-06-13 | 2019-05-28 | The Regents Of The University Of California | Particle size distribution measurements of particles and droplets using optical gel electrophoresis |
EP3252465A4 (en) * | 2015-01-26 | 2018-01-17 | Shimadzu Corporation | Noise level estimation method, measurement data processing device, and program for measurement data processing |
EP3260858A1 (en) * | 2015-02-16 | 2017-12-27 | Shimadzu Corporation | Noise level estimation method, measurement data processing device, and program for measurement data processing |
EP3130679B1 (de) | 2015-08-13 | 2018-02-28 | Cladiac GmbH | Verfahren und testsystem zum nachweis und/oder quantifizieren einer ziel-nukleinsäure in einer probe |
JP6635125B2 (ja) * | 2015-11-27 | 2020-01-22 | 株式会社ニコン | 顕微鏡、観察方法、及び画像処理プログラム |
CN111868519A (zh) * | 2017-11-15 | 2020-10-30 | 机械解析有限公司 | 用于分析气相色谱洗脱峰的方法和装置 |
US10916037B2 (en) * | 2018-12-13 | 2021-02-09 | Canon Kabushiki Kaisha | Method of encoding and decoding calibration marker identifiers |
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US4868749A (en) * | 1983-01-08 | 1989-09-19 | Fuji Photo Film Co., Ltd. | Signal processing method in autoradiography |
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-
1995
- 1995-12-20 US US08/579,204 patent/US5748491A/en not_active Expired - Lifetime
-
1996
- 1996-12-02 EP EP96942130A patent/EP0868702B1/en not_active Expired - Lifetime
- 1996-12-02 WO PCT/US1996/019242 patent/WO1997022942A1/en active IP Right Grant
- 1996-12-02 CA CA002240539A patent/CA2240539C/en not_active Expired - Fee Related
- 1996-12-02 AU AU11284/97A patent/AU702262B2/en not_active Ceased
- 1996-12-02 DE DE69620232T patent/DE69620232T2/de not_active Expired - Lifetime
- 1996-12-02 AT AT96942130T patent/ATE215245T1/de not_active IP Right Cessation
- 1996-12-02 JP JP52283697A patent/JP3555686B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0868702A1 (en) | 1998-10-07 |
AU1128497A (en) | 1997-07-14 |
ATE215245T1 (de) | 2002-04-15 |
WO1997022942A1 (en) | 1997-06-26 |
AU702262B2 (en) | 1999-02-18 |
DE69620232D1 (de) | 2002-05-02 |
JP3555686B2 (ja) | 2004-08-18 |
DE69620232T2 (de) | 2002-11-14 |
CA2240539C (en) | 2002-04-23 |
EP0868702B1 (en) | 2002-03-27 |
CA2240539A1 (en) | 1997-06-26 |
US5748491A (en) | 1998-05-05 |
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