JPH11501362A - Hydrogel-forming absorbent polymer coated with antimicrobial agent - Google Patents

Abstract

  (57) [Summary] The present invention relates to an antimicrobial hydrogel-forming absorbent polymer comprising a hydrogel-forming absorbent polymer and an antimicrobial agent, wherein the hydrogel-forming absorbent polymer is coated with an antimicrobial agent. The invention further relates to a method for producing such an antimicrobial hydrogel-forming absorbent polymer. The invention further relates to a disposable absorbent comprising an antimicrobial hydrogel-forming absorbent polymer.

Description

DETAILED DESCRIPTION OF THE INVENTION              Hydrogel-forming absorbent polymer coated with antimicrobial agent                                   background   Not only effective in absorbing body fluids like urine, blood, menstrual fluid etc., but also hygiene Various disposable absorbers are known in the literature that are designed to be suitable and comfortable to use . This type of disposable absorbent product usually consists of a liquid permeable topsheet material, absorbent core And a liquid-impermeable backsheet material. Variety of such objects Shape, size and thickness make their use even more comfortable and convenient Have been examined.   At one time, research on such disposable absorbers mainly focused on the absorptive capacity of objects. I have been. As a result, various absorbent polymers with high absorbency have been developed. This Such known absorbent polymers (also known as hydrogel-forming absorbent polymers) About 30 to 60 g of water can be absorbed per g of polymer.   More recently, research has focused on eliminating odors and disposable absorption over a relatively long period. For the prevention of skin diseases such as dermatitis, rash and redness caused by wearing the body Was. Many bodily fluids have an unpleasant odor, or air and And / or emits such an odor when in contact with bacteria. In addition, absorption in the absorber The collected urine and / or other exudates are from the skin flora, the normal microbial community on the skin It is converted to ammonia by the produced urease. This ammonia is then Causes dermatitis, rash and / or other forms of skin irritation. Skin in infants Such diseases are serious medical problems and, in extreme cases, can result in death.   Antimicrobials and germicides reduce microbial contamination and degradation of products, materials and systems. It is a chemical composition used for prevention. Specific application of antimicrobial agents and compositions Applications include, for example, cosmetics, pesticides, disinfectants, wood preservatives, food, animal feed, cooling Water, metalworking fluids, hospital and medical applications, plastics and resins, petroleum, pulp And paper, textiles, latex, adhesives, leather and animal skins, paint slurries Lee and disposable diapers.   For example, in Japanese Patent No. 4-17058, bacteria colibacillus and Ca It is said to prevent the occurrence of diaper rash caused by the growth of saprophytic bacteria such as ndida Discloses a disposable diaper. The disclosed disposable diapers are water permeable Topsheet, water-impermeable backsheet, and water absorption sandwiched between these sheets Consists of layers. The water absorbing layer is composed of a) a polyacrylate polymer, starch acrylonitrile. Tolyl graft copolymer hydrolyzate, starch acrylic acid graft copolymer -, Polyvinyl alcohol-acrylate copolymer, cross-linked acrylic with cross-linking agent And modified carboxymethyl cells produced by further cross-linking of acrylates Ammonia-adsorbed water-absorbing organic polymer selected from the group consisting of loin; and b. B) Benzalkonium chloride and / or glue contained in the water absorbing organic polymer It is further disclosed as consisting of chlorhexidine conate. In that document, Starting materials (eg, particulate silicon dioxide, cross-linked potassium acrylate) And a crosslinking agent such as ethylene glycol diglycidyl) The formation of organic polymer / fungicide materials by combining Is disclosed. Next, the obtained mixture causes a crosslinking reaction to form a crosslinked structure. Heated to form and the germicide is incorporated into the structure.   The diaper disclosed in Japanese Patent No. 4-17058 is contained in urine of a wearer. It is said that the absorbed ammonia is absorbed by the organic polymer, and the disinfectant is Inhibits the production of ammonia (formed by the breakdown of urea in urine) As said, we have found a shortcoming in this technology.   For example, the disinfectant is incorporated into the polymer, causing the polymer to swell in urine Until the fungicide does not start to work. In other words, the product is for example urination It does not take effect immediately.   In addition, (as described in Japanese Patent No. 4-17058, or Water-absorbing polymers (manufactured without the incorporation of fungicides into the polymer) Easy to generate Such dust production has a health impact on workers who inhale dust. Risk, increased cleaning of dust-removing machines, It has several disadvantages, including loss of product due to formation.   Based on the above, when used in a disposable absorber, the drainage of bodily fluids by the user Antimicrobial hydrogel-forming absorbent polymer ("A-HF" AP "). Such A-HF with minimal dust production There is also a need for a method of manufacturing an AP. Keep away from wearer's skin even after wetting A-HFAP-containing absorbent products that maintain an antimicrobial agent There is also a need.                                   Abstract   The present invention comprises a hydrogel-forming absorbent polymer and an antimicrobial agent, wherein the hydrogel-forming Antimicrobial hydrogel-forming absorbent polymer, wherein the absorbent polymer is coated with an antimicrobial agent About. Such materials can be used by users when used in disposable absorbers. Hydrogel-forming absorbent polymer has an immediate effect on draining body fluids Meets the need for a combination of and antimicrobial agents.   The invention comprises coating the hydrogel-forming absorbent polymer with an antimicrobial agent, It further relates to a method for producing such an antimicrobial hydrogel-forming absorbent polymer. this Such a method minimizes dust production associated with the production of hydrogel-forming absorbent polymers. To meet the process needs.   The present invention provides a disposable absorbent comprising an antimicrobial hydrogel-forming absorbent polymer. Regarding further. Such a structure effectively reduces foul odors and rashes, while Fulfills the need for an absorbent that keeps the active ingredient away from the skin of the user.   These and other features, aspects, and advantages of the present invention are described in connection with this disclosure and the accompanying drawings. Reading the scope of the claims will be apparent to one skilled in the art.                             BRIEF DESCRIPTION OF THE FIGURES   The specification ends with the claims which specifically identify and clearly claim the invention. However, the present invention will be more fully understood from the following description of preferred embodiments taken together with the accompanying drawings. It is considered well understood, where the same reference numbers represent the same elements:   Fig. 1 shows the inner surface of the diaper facing the viewer, Figure 2 is a plan view of a disposable diaper embodiment of the present invention, with parts cut away;   FIG. 2 shows the disposable diaper of FIG. 1 along the horizontal center line 110 of FIG. 1 is a cross-sectional view of one embodiment;   FIG. 3 is an enlarged view of another embodiment of the disposable diaper of FIG. 1, which is a part of FIG. Corresponding to; and   FIG. 4 illustrates the key components of the end product uptake test.                               Specific description   The following is a list of definitions for terms used herein.   "A-HFAP" means antimicrobial hydrogel-forming absorbent polymer.   "Body fluids" include urine, menstrual fluid and vaginal secretions.   “Comprising” means other steps and other ingredients which do not affect the end result Can be added. The terms "consisting of" and "consisting essentially of "Is included.   "Disposable" means to be washed or recycled or reused as an absorbent material. Absorbers that are not intended to be depleted (ie they are discarded after a single use and Or recycled, composted or disposed of in a manner compatible with the environment).   "HFAP" means a hydrogel-forming absorbent polymer.   “Unitary” absorbent articles are those that are separate Don't need separate operation parts like holder and liner Formed from separate parts that are merged and integrated to form an integrated About the absorber.   All percentages are by weight of total composition unless otherwise indicated. According to   All ratios are by weight unless otherwise indicated.   The invention has been described in detail in its product and process aspects as follows. ing.   The present invention relates to an antimicrobial hydrogel-forming absorbent polymer comprising HFAP and an antimicrobial agent For HFAP, it is coated with an antimicrobial agent.   In a preferred embodiment, the weight ratio of HFAP to antimicrobial is from about 100: 0.01 to about 100: 0.01. 100: 2, more preferably about 100: 0.02 to about 100: 1, even more preferably. Or about 100: 0.05 to about 100: 0.5.Hydrogel-forming absorbent polymer   The water-insoluble, water-swellable absorbent polymers useful in the present invention are "hydrogel-forming absorbents" Polymer ”(HFAP),“ hydrocolloid ”or“ superabsorbent ”polymer Carboxymethyl starch, carboxymethyl cellulose and hydrocarbyl Polysaccharides such as xypropylcellulose; polyvinyl alcohol and polyvinyl alcohol Nonionic type such as toluene; polyvinyl pyridine, polyvinyl morpho Linion and N, N-dimethylaminoethyl or N, N-diethylamino Clicks such as propyl acrylate and methacrylate and their respective quaternary salts There is an on type. Typically, HFAPs useful in the present invention are higher than sulfonic acids. Such anionic functional groups, more typically, have a large number of carboxy groups. The present invention Examples of polymers suitable for use in are made from polymerizable unsaturated acid bearing monomers There is something. Thus, such monomers have at least one carbon-carbon There are olefinically unsaturated acids and anhydrides with refinous double bonds. More Physically, these monomers are olefinically unsaturated carboxylic acids and anhydrides, It can be selected from olefinically unsaturated sulfonic acids and mixtures thereof.   Some non-acid monomers are also usually included in small amounts when producing HFAP in the present invention. Can be made. Such non-acid monomers include, for example, aqueous solutions of acid-bearing monomers. And water-dispersible esters and mono- and sulfonic acid groups There is a ma. Thus, any non-acid monomer has the following types of functional groups: Acid or sulfonic acid ester, hydroxyl group, amide group, amino group, nitrile Group, quaternary ammonium base, aryl group (for example, derived from styrene monomer) Phenyl groups). These non-acid monomers are Is an intellectual substance, for example, US Patent No. 4,072, issued February 28, 1978. No. 6,663 (Masuda et al.) And U.S. Patent Publications issued December 13, 1977. No. 4,062,817 (Westerman).   Olefinically unsaturated carboxylic acid and carboxylic anhydride monomers include acrylic Acid itself, methacrylic acid, ethacrylic acid, 3-chloroacrylic acid, cyanoacrylic acid Acid, methacrylic acid (crotonic acid), phenylacrylic acid, acryloloxyp Lopionic acid, sorbic acid, chlorosorbic acid, angelic acid, cinnamic acid, p- Chlorocinnamic acid, steryl acrylic acid, itaconic acid, citraconic acid, mesacone Acid, glutaconic acid, aconitic acid, maleic acid, fumaric acid, tricarboxyethyl There are acrylic acids represented by ren and maleic anhydride.   Olefinically unsaturated sulfonic acid monomers include vinyl sulfonic acid and allyl sulfonic acid. Aliphatics such as phonic acid, vinyl toluene sulfonic acid and styrene sulfonic acid Or aromatic vinyl sulfonic acid; sulfoethyl acrylate, sulfoethyl methacrylate Relate, sulfopropyl acrylate, sulfopropyl methacrylate, 2- Hydroxy-3-methacryloxypropyl sulfonic acid and 2-acrylamido Acrylic and methacrylsulfones such as do-2-methylpropanesulfonic acid There are acids.   HFAP preferred for use in the present invention has a carboxy group. These poly Mers include hydrolyzed starch-acrylonitrile graft copolymers, partially neutralized Hydrolyzed starch-acrylonitrile graft copolymer, starch-acryl Acid graft copolymers, partially neutralized starch-acrylic acid graft copolymers, Vinyl acetate-acrylate copolymer, hydrolyzed acrylonitrile Or acrylamide copolymers, somewhat network-crosslinked polymers of said copolymers -Partially neutralized polyacrylic acid and partially neutralized polyacrylic acid There are polymers. These polymers can be used alone or as two or more different polymers Can be used in the form of a mixture. Examples of these polymeric materials are described in U.S. Pat. 3,661,875; U.S. Pat. No. 4,076,663; U.S. Pat. No. 3,776, U.S. Pat. No. 4,666,983 and U.S. Pat. No. 478.   A more preferred polymeric material for use in making HFAP is a partially neutralized polymer. It is a slightly cross-linked polymer of crylic acid and its starch derivative. Further Preferably, HFAP is neutralized somewhat reticulated crosslinked polyacrylic acid (ie, polyacrylic acid). (Sodium acrylate / acrylic acid)) from about 50% to about 95%, preferably about 7%. Contains 5%. Network crosslinking renders the polymer substantially water-insoluble and absorbs HFAP. The characteristics of yield and extractable polymer content have been partially determined. These polymers The reticulating process and typical reticulating agents are described in US Pat. No. 4,076,663. This is described in more detail in the specification.   Furthermore, surface crosslinked HFAP is preferably used in the present invention. They are inside It has a higher level of cross-linking near the surface. "Surface" as used herein , Particles, fibers and the like. Porous HFAP (for example, porous grain Child, etc.), include exposed internal boundaries. What is a high level of crosslinking on the surface , The functional cross-linking level of HFAP near the surface indicates that the functional It usually means higher than the bridge level.   The degree of cross-linking from the surface to the interior varies in both depth and profile. Various. Thus, for example, the depth of surface cross-linking is shallow, leading to lower cross-linking levels. It changes relatively sharply. On the other hand, for example, the depth of surface cross-linking is important for the dimensions of HFAP. It can be a wide range of factors.   Degree of surface cross-linking, depending on considerations such as size, shape, porosity and functionality And the slope varies within a given HFAP. In the case of granular HFAP, the surface crosslinking is It changes according to the particle size, porosity, etc. Within HFAP (eg, small and large grains Depending on the variation of the surface: capacity ratio between the It is not unusual for things to change within a substance (eg, smaller particles are larger).   Surface cross-linking occurs when the final boundaries of HFAP (eg, grinding, extruding, It is usually done after it has been essentially defined (such as by forming). However, It is also possible to perform surface crosslinking simultaneously with the creation of the final boundary. In addition, part of the boundary The modification can be performed even after the surface crosslinking is introduced.   Several processes for introducing surface crosslinking have been disclosed in the art. This These include (i) bi- or polyfunctional reagents capable of reacting with the functional groups present in HFAP (Eg, glycerol, 1,3-dioxolan-2-one, polyvalent metal ion, Polyquaternary amine) is applied to the surface of HFAP; (ii) increasing the level of surface crosslinking Other additional reagents and possibly functionalities present in HFAP A bi- or multi-functional reagent capable of reacting with groups is applied to the surface (eg, monomer + (Iii) addition of crosslinking agent and initiation of second polymerization reaction); (iii) no additional polyfunctional reagent is added. However, additional reagents may create higher levels of cross-linking at or near the surface, etc. Introduced into the components present in HFAP during or after the main polymerization process To (E.g., no gap between the polymeric carboxylic acid and / or hydroxyl groups present) The formation of hydrate and / or ester cross-links and the cross-linking agent Heating to induce a suspension polymerization process that is present at higher levels); and ( iv) Table of hydrogels in which other substances introduce or obtain higher levels of crosslinking There are processes added to the surface, such as to reduce surface deformability. These surfaces Combinations of crosslinking processes may also be used simultaneously or sequentially. In addition to the crosslinking reagent , Other components also assist in the distribution of crosslinks (eg, spread and penetration of surface cross-linking reagents) Can be added to the surface to control.   A general method suitable for performing surface cross-linking of HFAP according to the present invention is described in 1985 U.S. Pat. No. 4,541,871 issued Sep. 17 (Obayashi); 19; Published PCT Application No. WO 92/16565 published on Oct. 1, 1992 (St. anley); published PCT application WO 90/08 published August 9, 1990. No. 789 (Tai); published PCT application WO No. 93/05080 (Stanley); U.S. patent issued April 25, 1989. No. 4,824,901 (Alexander); issued on January 17, 1989 U.S. Pat. No. 4,789,861 (Johnson); issued on May 6, 1986. U.S. Patent No. 4,587,308 (Makita); issued March 29, 1988. U.S. Pat. No. 4,734,478 issued (Tsubakimoto); November 1992 U.S. Pat. No. 5,164,459, issued May 17, (Kimura et al.); Published German Patent Application No. 4,020,780, published Aug. 29, 1980 (Da and published European Patent Application No. 50, published October 21, 1992. No. 9,708 (Gartner).   The HFAP is preferably of one type (ie, uniform), Mixtures of-may also be used in the present invention. For example, starch-acrylic acid graft Mixtures of ligers and partially reticulated crosslinked polymers of partially neutralized polyacrylic acid according to the invention Can be used with   The HFAP particles used in the present invention can vary in size, shape and shape. And / or form. HFAP particles have large maximum versus minimum dimensions Ratio (eg, granules, flakes, fines, interparticle aggregates, interparticle crosslinked aggregates, etc.) Without it, it can take the form of fiber, foam, and the like. HFAP is an example Low levels of one or more, such as powdered silica, surfactants, glues, binders, etc. It may be made of a mixture with the above additives. The components of this mixture are hydrogel The polymer forming component and the non-hydrogel forming polymer additive can be physically separated easily. But not physically and / or chemically.   HFAP is essentially non-porous or has substantial internal porosity. You.   For particles such as those described above, particle size is defined as the size determined by sieve size analysis. It is. For this reason, for example, U.S.A. Standard Testing with a 710 micron aperture  Particles remaining on Sieve (eg, No. 25 U.S. Series Alternate Sieve Design ation) is considered to have a size greater than 710 microns and Particles that pass through a sieve with an aperture of 500 microns and remain on a sieve with an aperture of 500 microns (eg, No. 3) 5 U.S.Series Alternate Sieve Designation) is 500-710 micron grain Particles passing through a sieve with a 500 micron opening Is considered to have a size smaller than the Hydrogel-forming absorbent polymer particles The mass median particle size of a given sample is the particle size that divides the sample in half on a mass basis. That is, half the sample by weight has a particle size smaller than the median size by mass. Thus, half of the samples have a particle size greater than the median mass size. Standard grain Degree plotting method (particle sampling that stays at or passes through a given sieve size opening The cumulative weight percent of the sample is plotted against sieve size on probability paper) is 50 If the% mass value does not match the sieve opening of the U.S.A. It is typically used to determine the median particle size. Hydrogel-forming absorbent polymer particles These methods for determining grain size are described in the rice published October 29, 1991. It is further described in US Pat. No. 5,061,259 (Goldman et al.).   For HFAP particles useful in the present invention, the particles are typically from about 1 to about 2000 microns. And more preferably in the size range of about 20 to about 1000 microns. Mass center grain The degree is usually about 20 to about 1500 microns, and more preferably about 50 to about 1000 microns. And even more preferably from about 100 to about 800 microns.   Within these size ranges, it can be large depending on the need for fast or slow absorption kinetics. Alternatively, it is preferable to select small particles. For example, in the case of non-porous particles, The rate of wetting usually decreases with increasing particle size. Increase gel layer permeability (ie, Sali ne Flow Conductivity (SFC) value) Particles or narrower size cuts of large or small particles (fraction It is also preferred to select) from bulk polymers. In some HFAP particles, A narrow size range cut that typically contains a large particle size within the size range described above, Performance Under Pressure (PUP) like ability and extractable polymer level Having high SFC values without any significant degradation in other HFAP properties I understood. Thus, for example, only the smallest mass fraction of particles is about 710 About 500 to about 710, having a size greater than or equal to or less than about 500 microns It is useful to use size cuts with median sizes in the micron range . On the other hand, the particles generally have a size in the range of about 150 to about 800 microns. Larger sizes are also useful.Antibacterial agent   Antimicrobial agents useful in the present invention can prevent or kill the growth of microorganisms. And can bind to HFAP, and more preferably binds to the surface of HFAP. Can be combined. Preferred antimicrobial agents are typically body fluids, more preferably A disposable absorber that prevents the growth of microorganisms typically found in body fluids collected Or something that can kill it. Although not limited to preferred antibacterial agents, Quaternary ammonium, phenol, amide, acid and nitro compounds and their mixtures Products, more preferably quaternary ammonium, acids and phenols, even more preferably Is a quaternary ammonium compound.   Preferred quaternary ammonium compounds include, but are not limited to, 2- (3-anilino Vinyl) -3,4-dimethyloxazolinium iodide, alkylisoquinolium Mbromide, benzalkonium chloride, benzethonium chloride, cetylpyridiuium chloride Chlorhexidine gluconate, chlorhexidine hydrochloride, lauryl trimethyl Ammonium, methylbenzethonium chloride, stearyltrimethylammonium chloride , 2,4,5-trichlorophenoxide and mixtures thereof, more preferably Or benzalkonium chloride and chlorhexidine gluconate, even more preferred Or benzalkonium chloride.   Preferred phenolic compounds include, but are not limited to, benzyl alcohol, p- Chlorophenol, chlorocresol, chloroxylenol, cresol, o- Cimen-5-ol (BIOSOL), hexachlorophen, hinokitiol, isop Propyl methylphenol, parabens (methyl, ethyl, propyl, butyl, With sodium, isopropyl and / or sodium methyl substituents) , Phenethyl alcohol, phenol, phenoxyethanol, o-phenylph Enol, resorcinol, resorcinol monoacetate, sodium parabens, Thorium phenol sulfonate, thioxolone, 2,4,4'-trichloro- 2'-hydroxydiphenyl ether, zinc phenol sulfonate and it These mixtures, more preferably sodium parabens.   Preferred amides include, but are not limited to, diazolidinyl urea, 2,4-imida Zolidinedione (HYDATOIN), 3,4,4'-trichlorocarbanilide, 3-tri Fluoromethyl-4,4'-dichlorocarbanilide, monoethano undecylenate Amines and mixtures thereof, more preferably diazolidinyl urea and 2 2,4-imidazolidinediones, even more preferably 2,4-imidazolidinedio There is a   Preferred acids include, but are not limited to, benzoate, benzoic acid, citric acid, Doroacetic acid, potassium sorbate, sodium citrate, sodium dehydroacetate , Sodium salicylate, sodium salicylate, salicylic acid, sorbic acid, Undecylenic acid, zinc undecylenate and mixtures thereof, more preferably Benzoic acid, citric acid, salicylic acid and sorbic acid, even more preferably citric acid There are acids and sorbic acid.   Preferred nitro compounds include, but are not limited to, 2-bromo-2-nitro-2, 3-propanediol (BRONOPOL), methyldibromoglutaronitrile, propyl There are ren glycol (MERGUARD) and their mixtures.Method for producing antimicrobial hydrogel-forming absorbent polymer   The present invention relates to an antimicrobial hydrogel comprising coating HFAP particles with an antimicrobial agent. The present invention further relates to a process for producing a polymer forming absorbent polymer. As used herein, "coating "Minging" means that the antimicrobial agent is on at least a portion of the surface of HFAP. ing. Preferably, the antimicrobial agent is applied on all of the surface of the HFAP. theory Antimicrobial agents bind to the surface of HFAP through Coulomb interaction It is thought that it is. When A-HFAP is hydrated, most of the antimicrobial agents Ionically attracted to HFAP. However, some antimicrobial agents are May diffuse into space and fibers.   If the antimicrobial agent is in the form of small particles or powder, the antimicrobial agent Various techniques and equipment used to apply quality (eg, coating) Can be applied by In other cases where the antimicrobial agent is in liquid form, the antimicrobial agent Applicable by various techniques and equipment used to apply to substances (eg For example, it is coated on HFAP). As a result, the A-HFAP of the present invention Obtained as follows.   In a preferred embodiment, the antimicrobial agent is dissolved in a solvent to make a solution. antibacterial Agents are based on various techniques and techniques used to dissolve substances in solvents known in the art. It can be dissolved in a solvent depending on the type and the device. In a further preferred embodiment, Organic solvents, preferably water, are used as solvents. Preferably, the anti- The concentration of the fungicide is about 2 to about 25% by weight, more preferably about 5 to 15%.   In some embodiments, antimicrobial agents that are insoluble in organic solvents can also be used. More preferred form In some embodiments, a polar organic solvent is used as the solvent. In such an embodiment, hydrophilic A mixed solvent of organic solvent and water is used as a solvent for the antibacterial agent. Preferred organic Non-limiting examples of solvents include solvents such as methanol, ethanol or propanol. Alcohol; acetone; dimethylformamide (DMF); dimethyl sulfo Oxide (DMSO); hexylmethylphosphoric triamide (HMPT); and There is a mixture of these. In another preferred embodiment, hexane, toluene, xylene Non-polar solvents such as benzene and benzene can also be used as one of the organic solvents.   After preparing the solution, the solution is applied on HFAP, whereby the intermittent mixture make. More specifically, an amount of the solution is applied on HFAP. The solution is antibacterial On the absorbent gel particles to provide a partial or complete coating of HFAP with the agent Coating, dumping, pouring, dropping, spraying liquid mixtures on Used to apply the solution to the substance, including spraying, condensing or dipping It can be applied by various techniques and devices. In this way, if the mixture is intermittent, The liquid is on at least a portion (eg, a coat) of the surface of the HFAP. Preferably The solution is on all surfaces of the HFAP particles.   The amount of antimicrobial agent sufficient to exhibit effective antimicrobial properties depends on the chemical composition of HFAP and Physical form of HFAP, eg, HFAP particle size, antimicrobial chemical composition and molecular weight And will vary based on several factors, such as the method of applying the antimicrobial agent.   After making the intermittent mixture, at least some of the solvent is removed from the intermittent mixture. Good Preferably, at least about 80% of the solvent, more preferably 95% or more, most preferably About 100% is removed from the intermittent mixture. Solvent removal includes evaporation, filtration, and washing. Separation or removal of liquids from liquid-solid mixtures, including or their combinations Can be performed by the various techniques and equipment used for   In a preferred embodiment, the antimicrobial agent is HFAP after treatment of surface crosslinking of the HFAP particles. Applied above. On the other hand, in another embodiment, the antimicrobial agent is a surface cross-linked of HFAP Applied on HFAP before processing. In addition, in another embodiment, the application and And cross-linking can be performed simultaneously.   In a preferred embodiment, the resulting A-HFAP has several shapes and sizes. Can be provided. For example, absorbent materials are typically particles, sheets, films In the form of cylinders, blocks, fibers, filaments or other shape elements be able to. More preferably, the absorbent is in particulate form.Absorber using antibacterial hydrogel-forming absorbent polymer   The A-HFAP according to the invention can be used versatile in many fields of use. For example , A-HFAP is a packing container; drug delivery device; Burning device; Ion exchange column material; Building material; Seed sheet or Is an agricultural or horticultural substance such as a water storage substance; sludge or oil dehydrating agent, dew formation It can be used in industrial applications such as inhibitory substances, desiccants and humidity regulating substances.   Due to the unique absorption and antibacterial properties of the A-HFAP of the present invention, they It is particularly suitable for use as an absorbent core in a body, especially a disposable absorbent. In this specification The term "absorber" as used refers to objects that absorb and contain bodily fluids and More specifically, the wearer is required to absorb and contain various liquids discharged from the body. Related to an object placed at or near the body.   Generally, the absorbent comprises: (a) a liquid-permeable top that is placed near the body of the wearer. (B) liquids placed away from the wearer's body and near the wearer's clothing; A transparent backsheet; and (c) placed between the topsheet and the backsheet Made of absorbent core. The absorbent core comprises at least one of the above A-HFAPs of the present invention. Comprising seeds. Preferably, the absorbent core further comprises a support web, wherein the absorbent web is provided. A collection material is attached to the support web. On the other hand, the absorbent core covers the absorbent material. It also includes an envelope web. In yet another aspect, the absorbent core further comprises 2 It is made of layered tissue and the absorbent material is placed between the two layers.   In a more preferred embodiment, A-HFAP in the absorbent core has a base weight of about 60%. ~ About 1500g / m^Two, More preferably about 100 to about 1000 g / m^Two, Most preferred About 150 to about 500 g / m^TwoHas an absorbing substance.   In some preferred embodiments, the absorbent core or absorbent is a fiber or fluff pal (Fibrous or fibrous material), more specifically non-absorbable gelled fibers You. Such fibrous materials are used as reinforcement in the absorbent core to improve the liquid handling of the core. Then, it can be used as a co-absorbent with an absorbing polymer. Preferably The absorbent core or material comprises about 40 to about 100% by weight of A-HFAP and Consisting of about 60% to about 0% by weight of such non-absorbed gelling fiber material distributed.   In a preferred embodiment, A-HFAP comprises at least one of the core or absorbent material. At a concentration of at least 40% by weight in the region, more preferably from about 60 to about 100%. You. In a more preferred embodiment, the absorbent comprises a fibrous matrix, where Shows that A-HFAP is distributed in a fibrous matrix.   Any type of fibrous material suitable for use in conventional absorbent products is absorbed by the present invention. Can be used for core or absorbent. Specific examples of such fibrous materials include Lulose fiber, modified cellulose fiber, rayon, polypropylene and polyes Tell fiber, for example, polyethylene terephthalate (DACRON), hydrophilic nylon (HY DROFIL). Examples of other fiber materials for use in the present invention include, for example, polyethylene. Polyolefins such as ren or polypropylene, polyacrylic, polyamide Surfactant-treated or silica derived from polystyrene, polyurethane, etc. There are hydrophobized hydrophobic fibers such as treated thermoplastic fibers. In fact, it sucks so much A sufficient absorption capacity to be useful for conventional absorption structures Hydrophobized fibers that do not provide webbing are absorbed by the absorbent core due to their good wicking properties. Suitable for use with. This is due to the high liquid uptake of the absorbent core in this absorbent core. Due to the lack of speed and gel blocking properties, the wicking properties of the fibers are Even if it is less important than capacity, it is just as important. Synthetic fiber is absorbent It is usually preferred for use in the present invention as the fiber component of (a). Most preferred is polyolefin Fiber, preferably polyethylene fiber.   Other cellulosic fibrous materials useful for the absorbent cores or absorbents of the present invention include chemical It is a cellulose fiber which has been hardened. Preferred chemically cured cellulose The fibers are made by internally cross-linking the cellulose fibers with a cross-linking agent, hardened screws It is a cellulose fiber that is bent and curled. Useful as hydrophilic fiber material in the present invention A suitable cured, twisted, curled cellulosic fiber is described in December 1989. U.S. Pat. No. 4,888,093 issued on Dec. 19 (Dean et al.); 1989. U.S. Pat. No. 4,889,595 issued Dec. 26, 2013 (Herron et al.); U.S. Pat. No. 4,889,596 issued Dec. 26, 1989 (Scho ggen et al.); U.S. Patent No. 4,889,59, issued December 26, 1989. No. 7, Bourbon et al .; and U.S. Pat. 898,647 (Moore et al.).   A preferred embodiment of the disposable absorber is a diaper. As used herein, "diaper The term "one" is worn around the lower torso of the wearer and More on clothing usually worn. Preferred diapers for diapers with absorbent core One configuration is disclosed in U.S. Pat. No. 3,860,003 issued Jan. 14, 1975. No. (Buell). On the other hand, the disposable in the present invention A preferred form of diaper is disclosed in U.S. Pat. No. 808,178 (Aziz et al.); U.S. Pat. No. 4,695,278 (Lawson); US Patent issued March 28, 1989. No. 4,816,025 (Foreman); and issued September 29, 1992 No. 5,151,092 issued to Buell et al. .   A preferred embodiment of the absorbent body of the present invention is an integral disposable absorbent body shown in FIG. Mutsu 20. FIG. 1 shows a flattened, uncontracted state (ie, elastic contraction FIG. 2 is a plan view of the diaper 20 of the present invention (returned), wherein a portion of the structure is a diaper. 20 has been cut out to show how to assemble it more clearly, facing the wearer. The diaper 20 has an inner surface 40 facing the viewer. It is shown in Figure 1 Thus, the diaper 20 is joined to the liquid-permeable topsheet 24, the topsheet. Liquid-impermeable back sheet 26, between top sheet 24 and back sheet 26 Made of a containment assembly 22 consisting of an absorbent core 28 placed in Is preferred. The absorbent core 28 has a pair of opposed longitudinal ends 60, an inner surface 62 and an outer surface. It has a surface 64. The diaper has side panels 30, elastic leg cuffs 32, From the elastic waistband 34, preferably a pair of fixing members 37 and receiving members 38 Preferably, it further comprises a fastening system 36.   The diaper 20 has an inner surface 40 (facing the viewer in FIG. 1), Outer surface 42, rear waist area 44, front opposite to rear waist area 44 Between the waist region 46, the rear waist region 44 and the front waist region 46 The placed crotch region 48 and the perimeter defined by the outer edge or end of the diaper 20 ( The side edges are labeled 50 and the ends are labeled 52). It is shown in FIG. The inner surface 40 of the diaper 20 is placed near the body of the wearer during use. Consisting of a portion of the diaper 20 (ie, the inner surface 40 is at least And usually other parts joined to the topsheet 24). The outer surface 42 is comprised of a portion of the diaper 20 that is separated from the wearer's body (ie, The outer surface 42 is joined to at least a portion of the backsheet 26 and the backsheet 26. Other elements). "Jointed" as used herein The term is used when an element is directly attached to another element so that the element is directly Fixed form and by attaching the element to the intermediate material and then to the other element A form in which an element is indirectly fixed to another element is included. Rear waist area 44 And the front waist region 46 extends from the peripheral end 52 to the crotch region 48. Is running.   The diaper 20 has two centerlines, a longitudinal centerline 100 and It also has a lateral centerline 110. As used herein, "longitudinal" The term "drop" divides an upright wearer into two equal halves when the diaper 20 is worn. A line on the face of the diaper 20 that is normally (eg, substantially parallel) aligned with the face Related to the axis, axis or direction. "Lateral" and "lateral" as used herein The term "is interchangeable and generally perpendicular to the longitudinal direction (divides the wearer into Pertaining to a line, axis or direction in the diaper plane.   The containment assembly 22 of the diaper 20 includes a main body (shear) of the diaper 20. 1) as shown in FIG. The containment assembly 22 is Sheet 24, back sheet 26, and a pair of opposed vertical ends 60, inner surface 62, It is preferably made of an absorbent core 28 having an outer surface 64. The inner surface 62 The outer surface 64 is normally facing away from the wearer's body, usually facing the wearer's body. You. Containment assembly when absorber consists of separate holder and liner -22 are usually made up of a holder and a liner (ie, containment assembly). The lead 22 is made of one or more layers of material to make the holder, and the liner is G, backsheet and absorbent core). Integrated absorber In this case, the containment assembly 22 may have other features to form a composite diaper structure. Diaper topsheet 24, backsheet 26 and absorbent core with added markings 28 is preferred.   FIG. 1 shows a case where the top sheet 24 and the back sheet 26 are the absorbent cores 28. Also preferred are containment assemblies 22 that also typically have large length and width dimensions. This shows a new aspect. The top sheet 24 and the back sheet 26 are made of the absorbent core 2 The diaper 20 protrudes from the end of the diaper 8 and forms a peripheral edge of the diaper 20. Top sheet 2 4, the backsheet 26 and the absorbent core 28 are assembled in various well-known forms, An exemplary containment assembly configuration is Kenneth, dated January 14, 1975. US issued to B.Buell, entitled "Shrinkable Sides of Disposable Diapers" Patent 3,860,003; to Kenneth B. Buell et al. On September 29, 1992. Issued "Dynamic elastic waist characteristic absorber with elastic bending hinge" and No. 5,151,092, entitled US Pat. Are incorporated herein by reference.   The absorbent core 28 is typically compressible, conformable and non-irritating to the wearer's skin. Can absorb and store fluids, such as urine and some other body exudates It is a collection. As shown in FIG. 1, the absorbent core 28 is attached to the side facing the garment and the body. It has a facing side, a pair of side ends, and a pair of waist ends. Absorbent core 28 Can be of various sizes and shapes (eg, square, engraved, "T" shaped, asymmetric, etc.) Manufactured and commonly used in disposable diapers in addition to containing the A-HFAP of the present invention Various liquid absorbent materials and finely ground wood pulp, commonly referred to as air felt. Such other absorbers may also be included. Examples of other suitable absorbent materials include creped Lullo wadding; melt brown polymer including coform ; Chemically cured, modified or crosslinked cellulose fibers; tissue wraps and Tissue including tissue laminate; Absorbent foam; Absorbent sponge; Super absorbent Absorbing polymer; Absorbing gelling substance; or any corresponding substance or combination of substances There is a fake.   The form and structure of the absorbent core 28 can vary (eg, the absorbent core Ripper zone, hydrophilic gradient, superabsorption gradient, or low average density and low average basis weight Has a volume uptake zone or has one or more layers or structures) . In addition, the size and the absorption capacity of the absorbent core 28 may vary from infants to adults. You may change it to suit your needs. However, the overall absorption capacity of the absorbent core 28 is Should be compatible with design load and application.   One aspect of the diaper 20 is an asymmetric, modified T-shaped with an ear in the front waist region. It has an absorbent core 28, but is generally square in the rear waist region. Wide Exemplified for use as the absorbent core 28 of the present invention, which achieved excellent acceptability and commercial success. The absorption structure was developed by Weisman et al. On September 9, 1986. U.S. Pat. No. 4,610,678 entitled "Structure"; U.S. patent issued to Weisman et al. Entitled "Absorber with Double Layer Core" No. 4,673,402; issued to Angstadt on December 19, 1989, " U.S. Pat. No. 4,888,231 entitled "Absorptive core with dusting layer" And issued to Alemany et al. On May 30, 1989, entitled "Low Density and Low U.S. Patent No. 4,834,7, entitled "High Density Absorber With Basis Weight Incorporation Zone" No. 35. The absorbent core was purchased from Aleman on August 10, 1993. entitled "Absorbent with elastic waist characteristics and high absorption power" issued by y et al. U.S. Patent No. 5,234,423; and Young, LaV on September 15, 1992. US issued to on and Taylor entitled "High Efficacy Absorber for Incontinence Treatment" As detailed in US Pat. No. 5,147,345, the absorption storage Dual core system with chemically hardened fiber uptake / distribution core throughout storage core It may be made of a system.   Topsheet 24 is preferably located near inner surface 62 of absorbent core 28 and is preferably Or by means of attachment means (not shown) as is well known in the art. And 26. Proper attachment means absorbs backsheet 26 It is described with respect to joining to the core 28. In a preferred embodiment of the present invention The top sheet 24 and the back sheet 26 are in direct contact with each other at the periphery of the diaper. And connect them directly to the absorbent core 28 by any suitable attachment means. By joining, they are indirectly joined together.   The topsheet 24 is elastic, soft, and non-irritating to the wearer's skin. Preferably. Further, the topsheet 24 is preferably liquid permeable, Liquid (eg, urine) is easily permeated from its thickness. Suitable topsheet 24 Include various materials such as woven and non-woven materials; Polymers such as plastic films and hydrohomed thermoplastic films Material; porous foam; reticulated foam; reticulated thermoplastic film; and thermoplastic Manufactured from scrim. Suitable woven and non-woven materials include natural fibers (eg, wood). Or cotton fibers), synthetic fibers (eg, polyester, polypropylene or Is a polymer fiber such as polyethylene fiber) or a set of natural and synthetic fibers It can be composed of a combination. The top sheet 24 passes through the top sheet 24. To keep the wearer's skin away from the liquid contained in the absorbent core 28 (ie, It is preferably made from a hydrophobic material to prevent wetting. Top sheet If the top sheet 24 is made of a hydrophobic material, at least the top sheet The surface is treated hydrophilic so that the liquid passes faster through the topsheet. this Means that body exudate is drawn from the top sheet 24 and absorbed by the absorbent core 28 Rather than to eliminate the possibility of over-flowing from the topsheet 24 is there. The topsheet 24 can be made hydrophilic by treating it with a surfactant. You. Suitable methods for treating the topsheet 24 with a surfactant include topsheets. Spraying 24 substances with surfactant, soaking the substance in surfactant Sometimes. A more detailed description of such treatments and hydrophilicity can be found in 1991 January 1. Entitled “Absorber with Multilayer Absorbing Layer” issued to Reising et al. U.S. Patent No. 4,988,344, and Reising on January 29, 1991. U.S. Pat. No. 4, entitled "Absorber with Rapidly Uptake Absorbent Core" issued to 988,344.   Another preferred topsheet comprises an aperture forming film. Opening forming film Preferred as topsheets because they are permeable to body exudates Non-absorbable yet non-absorbable, allowing liquid to return to the wearer's skin and re-wet it This is because the tendency to cause them to decrease is reduced. Therefore, the formed film in contact with the body Surface remains dry, thereby reducing body soiling and allowing the wearer to Creates a comfortable feel. A suitable formed film is 30 December 1975 Entitled "Absorbing Structure with Tapered Capillary" issued to Thompson U.S. Pat. No. 3,929,135 to Mullane et al. On Apr. 13, 1982. Rice issued, "Disposable absorber with stain resistant topsheet" No. 4,324,246; issued to Radel et al. On Aug. 3, 1982. U.S. Pat. No. 4,34, entitled "Elastic Plastic Webs Showing Fibrous Properties" 2,314; issued July 31, 1984 to Ahr et al. Entitled "A Macroscopically Expanded Three-Dimensional Plastic Web Showing a Tactile Impression and Cloth-like Tactile Impression" U.S. Patent No. 4,463,045; and Baird on April 9, 1991. U.S. Pat. No. 5,006,3, issued to U.S. Pat. No. 94.   The backsheet 26 of the present invention is generally placed away from the skin of the wearer, Exudates absorbed and taken up by 28 are diapers such as bed sheets and underwear A portion of the diaper 20 that prevents wetting articles in contact with the diaper 20; For this reason, The backsheet 26 is preferably impermeable to liquids (eg, urine) and is preferably Manufactured from thin plastic films, but other flexible liquid impermeable Transient materials may also be used (as used herein, the term “flexible” A substance that is elastic and easily conforms to the general shape and contours of the human body. ). However, the backsheet 26 allows the steam to escape from the diaper 20. Suitable materials for the backsheet 26 are from about 0.012 mm (0.5 mil) to about 0.05 A thermoplastic film having a thickness of 1 mm (2.0 mils), preferably It consists of polyethylene or polypropylene.   Even if the back sheet 26 of the present invention is made of a single material such as the above film, Or from several materials joined together to form the backsheet 26 You may come. For example, the backsheet may be made of one film or other material. A central region 74 of the same or different film or other material. It may have one or more outer regions 76 joined to region 74. One preferred embodiment In the back sheet 26, the central region 7 made of a liquid-impermeable non-opening film is used. 4 and two opposing outer regions 76 of an air permeable apertured film. You. The means by which any part of such a backsheet is joined includes adhesives, heating, Any means known in the art, such as pressing, heating and pressing and ultrasonic bonding including. Further, the backsheet 26 was bonded together to form a laminate It may be made up of several layers of material. The back sheet 26 is a laminate The layers need not be uniform throughout the backsheet. For example, The central region 74 of the sheet 26 may have more layers than the outer region 76 or a different layer of material. May be made from   The backsheet 26 is preferably located near the outer surface 64 of the absorbent core 28 and is preferably Preferably joined to it by any suitable attachment means known in the art. You. For example, the back sheet 26 may be a uniform continuous layer of adhesive, a patterned layer of adhesive, Or absorbent core by array of separate lines, spirals or spots of glue 28. Adhesives found to be satisfactory are St. Paul, Minnesota Manufactured by H.B. Fuller Company, Inc. and sold as HL-1258. Appropriate attachment consisting of an open pattern network of adhesive filaments An example of an instrument for this is "Disposable" issued to Minetola et al. On March 4, 1986. U.S. Pat. No. 4,573,986 entitled "Containment Clothes". Have been. Several lines of adhesive filament wound in a spiral pattern Another suitable means of attachment consisting of Sprague, Jr. No. 3,911,173 issued Nov. 1978 U.S. Patent No. 4,785,996 issued to Ziecker et al. U.S. Pat. No. 4,842,666 issued to Werenicz on June 27, 1989. This is illustrated by the apparatus and method set forth in the specification. Each of these patents Incorporated herein by reference. On the other hand, the attachment means has a heating connection, Pressure bonding, ultrasonic bonding, mechanical-mechanical bonding, or other such as known in the art. There are also suitable attachment means, or a combination of these attachment means.   In the embodiment of the present invention, the front waist region 46 and the rear waist region 44 In order to provide great elasticity, the absorbent core may have a backsheet 26 and / or a top. It is also conceivable that it is not joined to the sheet 24. In another aspect, a liquid impermeable An additional material such as a barrier material (not shown) may It is also conceivable to be placed between them. Such a barrier material is used for absorbing core 28. Or not. Further, the back sheet 26 is With or without a barrier material placed between the core 26 and the absorbent core 28. You may not.   Another preferred embodiment of the disposable absorbent article is a sanitary product. Preferred sanitary The article is disclosed in U.S. Pat. No. 4,285,343, issued Aug. 25, 1981 ( McNair); U.S. Patent No. 4,608,047, issued August 26, 1986. No. 4 (Mattingly); and U.S. Pat. No. 4, issued on Aug. 18, 1987. No. 6,687,478 (Van Tilburg). Made of sheet.   A preferred sanitary product is an agent serial number filed on November 30, 1992. No. Entitled "Absorbent with elastic side flaps" of JA-09RM No. 984,071 to Yasuko Morita, co-pending general assignment. Wings, side flaps and other structures and elements as ing.   Particularly preferred disposable absorbers made from A-HFAP have a low surface wetting tendency . For such objects, even after wetting, release the antimicrobial agent from the user's skin. Can be easily placed. Disposable absorbers are backsheet, topsheet, uptake And the absorbent core is made of the A-HFAP of the present invention. You. Such an absorbent is preferably greater than about 1.9 ml / sec at the first squirt and It has a total final product uptake rate of about 0.3 ml / sec or more in four jets (test method described below). The folded stack height of such an absorber is preferably about 9.9 m per pad m, more preferably about 6 mm or less. Preferably, the products of such products The topsheet measures from about 0.05 to about 1 g, as measured by the final product wetness test (described below). Liquid below, more preferably about 0.5 g or less, more preferably about 0.2 g or less Retain the underlying liquid, even more preferably no more than about 0.15 g.   FIG. 2 shows an example of such a disposable absorber in a diaper form. . FIG. 2 shows the disposable diaper of FIG. 1 along the horizontal center line 110 of FIG. It is sectional drawing of such an aspect. This figure shows the back sheet 26, the core cover 22 , A cross-sectional view of the absorbent core 28, the top sheet 24 and the elastic leg cuff 32 is shown. I have. This embodiment differs in that an additional element, the uptake / distribution layer 105, has been added. 1 is different from that shown in FIG.   FIG. 3 is an enlarged view of another embodiment of the disposable diaper of FIG. Part. In this embodiment, the topsheet 24 is the first topsheet layer 11 5 and the second topsheet layer 120. First topsheet layer 115 and The second topsheet layers 120 are preferably heat bonded together. Ingest / Distribution Layer 105 comprises a first acquisition / distribution layer 125 and a second acquisition / distribution layer 130. You. The first uptake / distribution layer 125 preferably includes a spatula on the second topsheet layer 120. Iral glue is joined. Preferably, the first acquisition / distribution layer 125 and the second The two acquisition / distribution layers 130 are not joined together.   The embodiment shown in FIG. 2 or FIG. 3 shows a reduced tendency for surface wetting, and The antimicrobial agent can be easily separated from the user's skin even after wetting. Exchange In other words, such an embodiment would include an antimicrobial agent when contacted with A-HFAP. Liquids, such as urine, that have returned to the user's skin, causing antimicrobial It reduces the chance of contact with the skin.   Topsheet 24 and uptake preferred for such a surface wettability reducing absorber The distribution / distribution layer 105 material includes:   Preferred topsheet 24 materials are Fiberweb North America, Inc. (Simpsonvi lle, South Carolina, U.S.A.). that is About 2.2 dtex polypropylene fiber and easily removable surfactant About 20-22g / m made from Inish)^TwoConventional thermal bonding carded web I.e. in the first liquid invasion it is very hydrophilic but wets many times And it becomes essentially as hydrophobic as the base polypropylene.   More preferably, the topsheet 24 material is commercially available from Havix Co., Japan. S-2355. It is a two-layer composite material, carding and air Made from two synthetic surfactant-treated bicomponent fibers using Roo Technology Have been. The first topsheet layer 115 is preferably a polypropylene / polypropylene Pyrene bicomponent fiber, e.g., a low melting point polypropylene for the exterior and a high melting point It is polypropylene. The second topsheet layer 120 is preferably made of polyethylene / Polyethylene terephthalate bicomponent fiber, e.g., low-melting polyethylene The fiber core is high melting point polyethylene terephthalate. First topsheet layer 11 5 preferably has a weak hydrophilic surfactant and the second topsheet layer is preferably Has a common hydrophilic surfactant. The total basis weight of a typical material is about 20-22 g / m^TwoIt is.   Preferably, the uptake / distribution layer 105 is, for example, a Polymer Group, Inc., North Ame. rica (Landisiville, New Jersey, U.S.A.) It is made of such a carded resin bonded high loft nonwoven material. They are 6dtex Made of polyethylene terephthalate fiber, about 43g / m^TwoWith a basis weight of I have. On the other hand, the acquisition / distribution layer 105 is a trade name of Weyerhaeuser Co. made from chemically treated hardened cellulosic fibrous materials available from ing. In another preferred embodiment, the acquisition / distribution layer 105 has the trade name FLIN Wood pallets commercially available from Weyerhaeuser Co. (United States) under T RIVER It is made of conventional cellulose fluff material, also known as pulp.   The present invention relates to incontinence briefs, adult incontinence products, training pants, diaper insulators. Commercially known by other names, such as towels, makeup tissues, paper towels, etc. It can be applied to other absorbers.Test method a.General   All tests are performed at about 23 ± 2 ° C. and about 50 ± 10% relative humidity.   Unless specified, the specific synthetic urine used in the test method is JAYCO SYNURINE Commonly known as Jayco Pharmaceutic of Camp Hill, Pennsylvania Commercially available from als Company. The prescription of synthetic urine is KCl 20 g / l, Na_Two SO_Four  2.0 g / l, (NH_Four) H_TwoPO_Four  0.85 g / l, (NH_Four)_TwoHPO_Four   0.15 g / l, CaCl_Two  0.19 g / l and MgCl_Two  0.23g / L. All chemicals are reagent grade. The pH of synthetic urine is about 6.0 to about 6 . 4 range. b.Final product uptake test   In FIG. 4, the absorption structure 10 is pumped from a height 5 cm above the sample surface (Co 15m using Model 7520-00 supplied by Le Parmer Instruments, Chicago, U.S.A. It is loaded with a 75 ml squirt of synthetic urine at a rate of 1 / s. Timer for urine absorption time Recorded by Ejects exactly every 5 minutes until the object is fully loaded Is repeated every 5 minutes. This test data is created by loading four times.   The test sample with the absorbent core, including the topsheet and backsheet, Form stand in the perspex box (only its base 12 is shown) It is arranged to be flat on the seat 11. Substantially 5cm diameter opening in the center A perspex plate 13 is placed on the sample. Synthetic urine goes to the opening The sample is introduced into the sample from the cylinder 14 which has been inserted and adhered. Electrode 15 absorbs The lowermost surface of the plate is applied in contact with the surface of the structure 10. electrode Is connected to the timer. The weight 16 of the plate is similar to the weight of the baby, for example. Put on top. 50g / cm^TwoPressure is typically utilized in this test.   When the test liquid is introduced into the cylinder, it typically accumulates on the absorbent structure. Thus, an electric circuit is formed between the electrodes. This starts the timer. Timer -When the absorbing structure absorbs urine squirt and the electrical contact between the electrodes is lost Stop.   The uptake rate is expressed as the volume of effluent (ml) absorbed per unit time (second). Stipulated. The uptake rate is calculated for each effluent introduced into the sample. Of particular interest in the context of the present invention are the first and last of the four eruptions.   This test is intended to evaluate products with an absorption capacity of about 300 to about 400 ml. Mainly set. Products with very different capabilities must be evaluated In particular, the setting of the liquid volume per spout is reasonably about 20% of the theoretical capacity. Adjustments should be made and deviations recorded. c.Final product wetness test   The disposable absorber is shown in FIG. 4 as described in the final product uptake test section above. Placed on the same device, with the following differences: 225 ml of synthetic urine is absorbed Loaded during body sample. The load was 3 sprays of 75 ml each at 3 minute intervals. Do. Additional pressure beyond negligible pressure arising from perspex plate Do not put on.   After the loading of 225 ml of synthetic urine is completed, the perspex plate is removed. 12 Two filter papers with dimensions of cm × 12 cm (Hollingsworth & Vo se, United Kingdom supply, type ERT FF3. W / S) is weighed and then It is put on urine load diaper. 2kg load in 10cm × 10cm area for 2 minutes Run over filter paper (ie, 0.28 psi). filter The paper is removed and weighed again. Diaper rewetting value is filter paper Weight increase (g). d.In-bag stacking height   In essence, the in-bag stacking height should be as low as the carton as supplied on the market. Or the height of the stack of absorbent products packed in the bag and measure the height of this stack. Investigate by dividing the height by the number of objects to be thrown.   Remove one of the bags and take the measurement or use a suitable instrument (INSTRON Instrument) pressure of the packed bag with a stress-strain measuring device such as that provided by This can be done by imitating force.   This test is based on a “folded” product, ie the front and rear parts of the object are bag So that there is only one in the cross (width) direction of the object around the center of the object It has been done mainly with products with fold lines. Non-fold or tri-fold product (3 layers ), The results need to be corrected accordingly. e.Basis weight   Basis weight is often referred to for various substances. These essentially add to the weight of the specimen It is obtained by dividing by the area. The size of the area and the number of re- Depends on uniformity. f.Hydrophilic / hydrophobic   Hydrophilic (and thus wettable) typically refers to the liquid and solid contact involved Said in terms of angle and surface tension. This was edited, for example, by R.F.Gould American Chemical entitled “Contact Angle, Wetability and Adhesion” It is described in detail in Society publications (copyright 1964). In the context of the present invention Can classify substances into three groups:   Substances that are "highly hydrophilic" (abbreviated as "h +"): these are usually less than about 80 degrees Have antennae. Examples include when treated with effective and strong surfactants (at least Cellulose fibers and olefin polymers when exposed to moisture for the first time) is there.   Substances that are "essentially hydrophobic" (abbreviated "h-"): these are usually about 100 degrees It has the above contact angle. Examples are interfaces (both surface and resin blended) There are pure olefins without activator (polyethylene / polypropylene).   Materials that are "moderately hydrophilic" (abbreviated as "ho"): these have a contact angle of about 90 degrees Having. Examples include less effective resin-loaded surfactants and such Having other less hydrophilic surfactants applied to the surface of the olefin, There are polypropylene / polyethylene.   The following examples further describe and demonstrate preferred embodiments within the scope of the present invention. I have. Examples are given for illustrative purposes only and should be considered as limitations of the present invention But many variations are possible without departing from its spirit and scope. is there.                                   Example 1   This example shows a method for producing HFAP used in the present invention.   Sodium acrylate 74.95 mol%, acrylic acid 25 mol% and trime 37% acrylic mono consisting of 0.05 mol% tyrolpropane triacrylate 4000 parts of an aqueous solution of sodium persulfate and 2.0 parts of 1-ascorbic acid The polymer was stirred and polymerized with 0.08 parts, and the gel hydrated powder finely divided into a particle size of about 5 mm was obtained. Get a rimmer. Drying the gel hydrated polymer at 150 ° C. with a hot air drier, Finely crushed with a hammer type fine crusher, sieved with a 20 mesh metal gauge, 20 mesh mesh as absorbent polymer A (having an average particle size of about 350 microns) Separate the overpowder.   0.5 part of glycerol, 2 parts of water and ethyl alcohol And then heat-treating the resulting mixture at 210 ° C. An absorbing polymer B whose surface portion is secondarily crosslinked is obtained.                                   Example 2   This example shows a method for producing A-HFAP of the present invention.   10 g of benzalkonium chloride (commercially available from Wako Chemical, Osaka, Japan) is steamed. Dissolve in 100 ml of deionized water. After complete dissolution, spray solution and spray nozzle Introduce into the air tank connected to the pump. Absorbent polymer B 500 of Example 1 g on a stainless steel plate to form a thin layer about 3mm thick Let it. 25 g of an aqueous solution of benzalkonium chloride is absorbed at room temperature with polymer B particles 500 Spray over g. The particles are then placed in a food mixer and stirred for 15 minutes . The benzalkonium chloride-coated absorbent polymer B particles were then Dry for 1 hour at 95 ° C in a oven or hot air for 10 minutes. Reduce the moisture level to less than 1% of the absorbing polymer B particles. Dry particles to size When gently pulverized into granules of 800 μm or less, polymer dust is slightly generated. I will. The particles obtained contain 0.5% benzalkonium chloride.                                   Example 3   This example illustrates the preparation of another embodiment of A-HFAP of the present invention. .   In this case, the same operation as in Example 2 is performed except that the absorbing polymer B is Aquali c CA-L76 (crosslinked sodium polyacrylate; commercially available from Nippon Shokubai Co., Ltd., Osaka, Japan) ). The process involves coating with benzalkonium chloride followed by poly Slightly produces mardust.                                   Example 4   This example illustrates an absorbent core having the A-HFAP of the present invention for a disposable absorbent. Is shown.   Southern Pine wood pulp is broken down and opened in an aeration chamber. About 3 The fibers having an average length of mm are dropped on a vacuum plate. Fiber laydown (f During the operation (iber laydown), the A-HFAP of Example 3 is dispersed in the wood pulp fibers. 2 30 to 400 g / m^TwoWood pulp fiber and 160-360 g / m^TwoA-HF A core containing AP is formed. The core is used for infant and / or adult incontinence. Suitable for use in mutsu applications. Typical composition of application example of L size infant diaper is as follows Is as follows:                                   Example 5   This example illustrates a disposable baby diaper having the A-HFAP of the present invention. I have.   The dimensions listed are for diapers for children ranging in size from 6 to 10 kg. is there. These dimensions are consistent with standard practice and may vary for children or adults of different sizes. It can be changed in proportion to the forbidden brief.   1. Backsheet manufactured according to U.S. Patent No. 4,687,478 0.0 20-0.038 mm liquid impermeable film; top and bottom width 33 cm Cuts 28.5 cm center width inward on both sides; 50.2 cm long   2. Top sheet: Carded thermal bonding staple length polypropylene fiber (Herc ules type 151 polypropylene); top and bottom width 33 cm; both 28.5 cm center notch on the inside on the side; 50.2 cm long   3. Absorbent core: 28.6 g of cellulose wood pulp and A-HFAP4 of Example 3 . 9 g; thickness 8.4 mm, calendering; top and bottom width 2 8.6 cm; cut inward on both sides with a center width of 10.2 cm; length 44.5 cm   4. Elastic leg bands: 4 individual rubber strips (2 on each side); width 4.7 7 mm; length 370 mm; thickness 0.178 mm (all dimensions above are loosened State)   The diaper uses a standard formula to apply the core material covered by the top sheet on the back sheet. In the above, it is manufactured by bonding.   Elastic band ("inside" corresponding to the band closest to and farthest from the core, respectively) And labeled "outside") to about 50.2 cm, along each longitudinal side of the core (Two bands on each side) Place between top sheet / back sheet. Inside along each side Side band approximately 55 mm from narrowest width of core (measured from inner edge of elastic band) Place. This is a flexible top between the inner elastic and curved ends of the core Spacing elements made of sheet / backsheet material provided along each end of the diaper You. The inner bands adhere along their length when stretched. Top sheet / The backsheet assembly is flexible and the glued band is Shrink to stretch each side.   The resulting diaper exhibits combined liquid absorption and antimicrobial properties.                                   Example 6   This example illustrates an adult incontinence product having A-HFAP of the present invention.   According to the manufacturing procedure of Example 4, 24-40 g of wood pulp fiber and A-HFAP10 Forms a heavy core with ２０20 g. The core is then removed from the liquid impermeable polybag Insert between the sheet and liquid permeable topsheet to form an adult incontinence product .                                   Example 7   This example is for a light weight panty liner product having A-HFAP of the present invention. Is shown.   Light weight panty liners suitable for use during menstruation have pads. So The pad is 117cm in surface area^TwoAnd 3 g of wood pulp fiber and A- Contains 1.5 g of HFAP. The pad was subsequently replaced by U.S. Pat. No. 4,463,045. Between the topsheet of the porous film and the liquid-impermeable backsheet. The sheet is made according to U.S. Pat. No. 4,687,478. The resulting pantilai The nut exerts combined liquid absorption and antimicrobial properties.                                   Example 8   This example shows a physiological pad with A-HFAP of the present invention.   A sanitary napkin-shaped sanitary with two flaps extending outward from the absorbent core No. 4,687, issued to Van Tillburg, issued Aug. 18, 1987. 478. However, the pads used are surface 117cm product^TwoWith 6 to 12 g of wood pulp fiber and the A-HFAP of Example 2 Contains 1-3 g. Liquid permeable topsheets are disclosed in US Patent No. 4,463,04. Produced according to No. 5. Liquid impermeable backsheets are disclosed in U.S. Pat. No. 4,687,47. Produced according to No. 8. The resulting menstrual pad has combined liquid absorption and antibacterial Demonstrate the nature.   Each aspect and aspect of the invention described herein has improved efficacy and improved efficacy. It has many surprising advantages, including improved processability. For example, in HFAP Coating the surface of HFAP with an antimicrobial agent rather than blending an antimicrobial agent This allows the antimicrobial agent to act as soon as the liquid enters the absorbent core. Conversely, anti Once the fungicide has been incorporated into HFAP, its efficacy is as follows: I'll be late until I stop.   In addition, for example, coating HFAP with an antimicrobial agent can Reduces the emission of strike particles. This reduction in HFAP dust particles is Safer environment, reduced downtime spent cleaning processing equipment, and material loss Causes loss prevention.   All documents, patent applications and issued patents mentioned above are incorporated by reference in their entirety. And incorporated herein.   The examples and embodiments described herein are for illustrative purposes only and Various modifications or changes will occur to those skilled in the art, and the spirit and scope of this application and the accompanying It will be understood that it is encompassed by the appended claims.

────────────────────────────────────────────────── ─── Continuation of front page    (81) Designated countries EP (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, L U, MC, NL, PT, SE), OA (BF, BJ, CF) , CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG), AP (KE, LS, MW, SD, S Z, UG), UA (AM, AZ, BY, KG, KZ, MD , RU, TJ, TM), AL, AM, AT, AU, AZ , BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, G E, HU, IL, IS, JP, KE, KG, KP, KR , KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, P L, PT, RO, RU, SD, SE, SG, SI, SK , TJ, TM, TR, TT, UA, UG, US, UZ, VN (72) Inventor Reiko Nakamura             1-4-17-101 Koshienguchi, Nishinomiya City, Hyogo Prefecture (72) Inventor Motohiro Shimizu             5-5,303 Hashizuka-cho, Nishinomiya City, Hyogo Prefecture (72) Inventors Resai, Ebrahim             Hyogo Prefecture Kobe City

Claims (1)

[Claims]   1. a) a hydrogel-forming absorbent polymer, and   b) Antibacterial agent Wherein the hydrogel-forming absorbent polymer is coated with an antimicrobial agent, Hydrogel-forming absorbent polymer.   2. The antimicrobial agent is benzalkonium chloride or chlorhexidine. 2. The antimicrobial hydrogel-forming absorbent polymer according to 1.   3. The antimicrobial hydroid according to claim 2, wherein the antimicrobial agent is benzalkonium chloride. Gel-forming absorbent polymer.   4. The ratio of antimicrobial agent to polymer is from about 100: 0.01 to about 100: 2; The antimicrobial hydrogel-forming absorbent polymer of claim 1.   5. An antimicrobial agent comprising coating the hydrogel-forming absorbent polymer with an antimicrobial agent. For producing a water-soluble hydrogel-forming absorbent polymer.   6. The method of claim 5, wherein the antimicrobial agent is benzalkonium chloride.   7. An antimicrobial hydrogel-forming absorption produced by the method of claim 5. polymer.   8. 9. An antimicrobial hydrogel-forming absorbent polymer according to claim 1. Disposable absorber.   9. 9. An antimicrobial hydrogel-forming absorbent polymer according to claim 1. Disposable diapers.   10. a) Back sheet   b) Top sheet   c) uptake / distribution layer, and   d) consisting of the antimicrobial hydrogel-forming absorbent polymer of claim 1.     Absorbent core A disposable absorbent comprising:   Absorber is about 1.9ml / sec or more in the first spout and about 0.3ml / sec or more in the fourth spout Final product take-in speed and fold-stack height of less than about 9.9mm per pad Wherein the topsheet has about 0.5 to about 1 g as measured by the final product wetness test Absorber that holds the following liquids.