JPH1147265A - Two baloon catheter - Google Patents
Two baloon catheterInfo
- Publication number
- JPH1147265A JPH1147265A JP9202938A JP20293897A JPH1147265A JP H1147265 A JPH1147265 A JP H1147265A JP 9202938 A JP9202938 A JP 9202938A JP 20293897 A JP20293897 A JP 20293897A JP H1147265 A JPH1147265 A JP H1147265A
- Authority
- JP
- Japan
- Prior art keywords
- blood
- patient
- catheter
- lumens
- lumen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- External Artificial Organs (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
Description
【発明の属する技術分野】本発明は、主に肝臓癌治療に
おける抗癌剤の大量肝動脈内投与に際して、選択的な送
脱血に使用する２バルーンカテーテルに関するものであ
る。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a two-balloon catheter used for selective blood supply and withdrawal when a large amount of an anticancer drug is administered into a hepatic artery in the treatment of liver cancer.
【従来の技術】肝臓癌は外科的切除が治療の第一選択と
なっているが切除困難な進行例や切除後も局所再発が多
発していた。従来より抗癌剤の大量肝動脈内投与が抗腫
瘍効果に著しい効果があることは明らかであったが、同
時に全身的副作用の問題があり、両面を克服できるシス
テムの開発が急務となっていた。そこで本発明者らは、
肝動脈内に大量に投与された抗癌剤を血液ごと肝静脈よ
り選択的に脱血し、活性炭濾過した後に患者へ送血する
システムにより前記抗腫瘍効果および全身的副作用の防
止効果の両面で著しい効果を有することを明らかにし
た。しかしながら本法は図４のように一方の鼡径部より
バルーンカテーテル（脱血管）を肝静脈分離付近へ挿入
し、更に下肢の脱血を行うためにもう一方の鼡径部より
カテーテル（脱血管）を挿入し、これらの血液を活性炭
濾過器およびポンプを介して腋下より挿入したカテーテ
ル（送血管）で心臓へ返血するシステムのため、両鼡径
部、腋下の計３箇所の静脈切開が必要であり、更に肝静
脈血を選択的に脱血するため閉鎖バルーン等で血流を遮
断する操作も加わり、手技が煩雑なばかりでなく患者の
侵襲も大きいため今後本システムの臨床的普及や反復治
療を推進する上で、より簡便なシステム化が望まれてい
た。2. Description of the Related Art Surgical resection is the first choice of treatment for liver cancer, but local recurrence has frequently occurred even in advanced cases where resection is difficult or after resection. It has been clear that administration of a large amount of anticancer drug into the hepatic artery has a remarkable effect on the antitumor effect, but at the same time, there is a problem of systemic side effects, and there is an urgent need to develop a system that can overcome both sides. Therefore, the present inventors
A system that selectively removes blood from the hepatic vein with anticancer drugs administered in large amounts into the hepatic artery from the hepatic vein, filters the charcoal, and sends the blood to the patient. It was clarified to have. However, in this method, as shown in FIG. 4, a balloon catheter (evacuated blood vessel) is inserted from one inguinal area near the hepatic vein separation, and a catheter (evacuated blood vessel) is inserted from the other inguinal area to perform blood removal of the lower limb. A system to insert the blood and return the blood to the heart with a catheter (blood vessel) inserted through the armpit through an activated carbon filter and a pump requires a total of three incisions in both groin and armpit In addition, in order to selectively bleed hepatic venous blood, an operation to cut off the blood flow with a closed balloon is also added, which not only complicates the procedure but also greatly invades the patient. In order to promote treatment, a simpler system was desired.
【発明が解決しようとする課題】本発明は、従来のシス
テムを簡便にすることを目的とするもので、１本で選択
的に送脱血が行えるカテーテルを提供しようとするもの
である。SUMMARY OF THE INVENTION An object of the present invention is to simplify a conventional system, and an object of the present invention is to provide a catheter which can selectively perform blood supply and withdrawal with a single device.
【課題を解決するための手段】即ち本発明は、表面に、
患者の血流を遮断するための２つのバルーンが付設され
ている可撓性チューブにおいて、該バルーンへ気体や液
体等を送り込む２つの気道ルーメン（内腔）に加え、患
者の血液を脱血するためのチューブ先端が封止されたル
ーメンと、逆に患者へ血液を送血するためのチューブ先
端が解放されているルーメンとを備え、目的に合わせて
各ルーメンに通ずる側孔が空けられていることを特徴と
する２バルーンカテーテルである。That is, the present invention provides a method for producing
In a flexible tube provided with two balloons for blocking a patient's blood flow, blood is removed from the patient's blood in addition to two airway lumens (lumens) for sending gas, liquid, and the like to the balloons. A lumen with a sealed tube tip and a lumen with an open tube tip for sending blood to the patient are provided, and a side hole communicating with each lumen is provided according to the purpose. It is a two-balloon catheter characterized by the above-mentioned.
【発明の実施の形態】以下、図面をもとに本発明につい
て詳細に説明する。図１は本発明に一実施例となる２バ
ルーンカテーテルの構造を示す図で、図２は本発明の他
の実施例を示す図である。本発明による２バルーンカテ
ーテルは、図１に示すように、可撓性のカテーテルチュ
ーブ（１）の前方部外周面に２個のバルーン（２）が気
密的に付設され、バルーン（２）の内腔はそれぞれカテ
ーテルチューブ（１）の気道ルーメン（１１）に通じて
いて、気道ルーメン（１１）の後端部には導入管（３）
が付設され、その後端のコネクター（４）に接続したシ
リンジから、カテーテルチューブ（１）の気道ルーメン
（１１）を通じてバルーン（２）内部に生理食塩水等を
注入できる構造となっている。カテーテルチューブ
（１）には更に先端が封止された脱血ルーメン（９）
が、また先端が解放された送血ルーメン（１０）がそれ
ぞれ後端部には分岐チューブ（５）が付設され、その後
端にコネクター（６）が接続されており、脱血ルーメン
（９）は２個のバルーン（２）の間に、送血ルーメン
（１０）は後側のバルーン（２）の後ろにそれぞれ１〜
５個の側孔（７）、（８）がチューブ外に開口している
が、側孔（７）、（８）は目的に合わせて位置を変えて
も、また付設せずとも特に制限はない。当然のことなが
ら、本発明は本実施例に限定されるものではなく、選択
的な送脱血を行うためにバルーンにより区画を分離し、
ルーメン数及び側孔位置をコントロールして、様々なア
レンジが可能である。例えば、図２は本発明の他の実施
例を示すもので、２個のバルーン（２）により３区画に
分けられ、チューブ先端へ通ずる送血ルーメン（１０）
と、２個のバルーン（２）の間の側孔（７）に通ずる脱
血ルーメン（９）と、後側ぼバルーン（２）の後ろの側
孔（８）に通ずる脱血ルーメン（１２）とを備えた５ル
ーメンチューブであり、このようにチューブ外径と必要
血流量の許す限りルーメン数を増やすことができる。次
に図３により本発明による２バルーンカテーテルの使用
方法を説明する。基本的には従来の図４に示した回路と
同様であるが、患者の体内へ挿入されているのは肝静脈
分離付近の上下をバルーン（２）で閉鎖した２バルーン
カテーテルが鼡径部より１本挿入されているのみであ
り、肝動脈（３２）から大量投与された抗癌剤（４０）
は肝静脈血（４１）ごとバルーン間の側孔（７）及び脱
血ルーメン（９）より脱血され、活性炭濾過器（２６）
およびポンプ（２５）を介した後送血ルーメン（１０）
へ再度戻し、側孔（８）からの下肢静脈血（４２）と一
緒にチューブ先端より心臓（３０）へ送血する。このよ
うに本２バルーンカテーテルを使用すると肝臓癌にとど
まらず流出静脈の分離が容易な腎臓、骨盤内臓器などの
腹部臓器の悪性腫瘍の治療にも本システムを行うことが
可能である。DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described below in detail with reference to the drawings. FIG. 1 is a view showing the structure of a two-balloon catheter according to one embodiment of the present invention, and FIG. 2 is a view showing another embodiment of the present invention. As shown in FIG. 1, in a two-balloon catheter according to the present invention, two balloons (2) are hermetically attached to a front outer peripheral surface of a flexible catheter tube (1). Each of the cavities leads to an airway lumen (11) of a catheter tube (1), and an introduction tube (3) is provided at the rear end of the airway lumen (11).
The syringe (4) at the rear end of the catheter (1) has a structure in which physiological saline or the like can be injected into the balloon (2) through the airway lumen (11) of the catheter tube (1). The catheter tube (1) further has a distal end sealed blood removal lumen (9)
In addition, a blood supply lumen (10) having an open distal end is provided with a branch tube (5) at the rear end, and a connector (6) is connected to the rear end, and a blood removal lumen (9) is provided. Between the two balloons (2), the blood delivery lumen (10) is 1 to 1 behind the rear balloon (2), respectively.
Although the five side holes (7) and (8) are open to the outside of the tube, the side holes (7) and (8) are not particularly limited even if the positions are changed according to the purpose or if they are not provided. Absent. Naturally, the present invention is not limited to this embodiment, and the compartments are separated by a balloon in order to perform selective blood supply and withdrawal,
Various arrangements are possible by controlling the number of lumens and the position of the side holes. For example, FIG. 2 shows another embodiment of the present invention, which is divided into three sections by two balloons (2), and a blood feeding lumen (10) leading to the tube tip.
A blood removal lumen (9) leading to a side hole (7) between the two balloons (2) and a blood removal lumen (12) leading to a side hole (8) behind the posterior balloon (2). This is a 5-lumen tube provided with the above, and the number of lumens can be increased as long as the tube outer diameter and the required blood flow rate are allowed. Next, a method of using the two-balloon catheter according to the present invention will be described with reference to FIG. 4 is basically the same as the circuit shown in FIG. 4 except that a two-balloon catheter, which is closed at the top and bottom near the hepatic vein separation with a balloon (2), is inserted from the inguinal region into the patient. The anticancer drug (40) which is only inserted and is administered in large amounts through the hepatic artery (32)
Blood is removed from the side hole (7) between the balloon and the blood removal lumen (9) together with the hepatic venous blood (41), and the activated carbon filter (26)
And post-blood delivery lumen via pump (25) (10)
To the heart (30) together with the venous blood (42) of the lower limb from the side hole (8). By using the present two-balloon catheter, the present system can be used not only for treating liver cancer but also for treating malignant tumors of abdominal organs such as kidneys and pelvic organs, which can easily separate outflow veins.
【発明の効果】以上に述べた如く、本発明による２バル
ーンカテーテルは１本で選択的に送脱血が行えるので、
患者に全身的副作用を与えずに抗癌剤の大量投与を行う
手技が、患者への侵襲も小さくより簡便に行うことがで
きる。As described above, the two-balloon catheter according to the present invention can selectively perform blood supply and withdrawal with one catheter.
The technique of administering a large amount of an anticancer drug without giving systemic side effects to the patient can be performed more easily with less invasion to the patient.
【図１】本発明の一実施例となる２バルーンカテーテル
の構造を示す図で、（ｂ）は（ａ）図のＡ−Ａ’断面図
である。FIG. 1 is a view showing the structure of a two-balloon catheter according to one embodiment of the present invention, and FIG. 1 (b) is a cross-sectional view taken along the line AA ′ of FIG. 1 (a).
【図２】本発明の他の実施例となる２バルーンカテーテ
ルの構造を示す図で、（ｂ）は（ａ）図のＡ−Ａ’断面
図である。FIG. 2 is a view showing the structure of a two-balloon catheter according to another embodiment of the present invention, and FIG. 2 (b) is a sectional view taken along the line AA ′ of FIG. 2 (a).
【図３】本発明の２バルーンカテーテルを使用した肝臓
癌に対する抗癌剤大量投与システム回路図である。FIG. 3 is a circuit diagram of a system for administering a large amount of an anticancer agent to liver cancer using the two-balloon catheter of the present invention.
【図４】従来の、肝臓癌に対する抗癌剤大量投与システ
ム回路図である。FIG. 4 is a circuit diagram of a conventional system for administering a large amount of an anticancer drug for liver cancer.
１ カテーテルチューブ 11 気道ルーメン
30心臓 ２ バルーン 12 脱血ルーメン
31肝臓 ３ 導入管
32肝動脈 ４ コネクター 20 ハ゛ル―ンカテ―テル（脱血
管） ５ 分岐チューブ 21 カテーテル（脱血管）
40抗癌剤 ６ コネクター 22 カテーテル（送血管）
41肝静脈血 ７ 側孔 23 閉鎖バルーン
42下肢静脈血 ８ 側孔 24 接続チューブ ９ 脱血ルーメン 25 ポンプ 10 送血ルーメン 26 活性炭濾過器1 catheter tube 11 airway lumen
30 heart 2 balloon 12 blood removal lumen
31 liver 3 introduction tube
32 Hepatic artery 4 Connector 20 Valve catheter (Avascular) 5 Branch tube 21 Catheter (Avascular)
40 Anticancer drug 6 Connector 22 Catheter (blood vessel)
41 Hepatic venous blood 7 Side hole 23 Closure balloon
42 Lower limb venous blood 8 Side hole 24 Connection tube 9 Blood removal lumen 25 Pump 10 Blood delivery lumen 26 Activated carbon filter
Claims (1)
つのバルーンが付設されている可撓性チューブにおい
て、該バルーンへ気体や液体等を送り込む２つの気道ル
ーメン（内腔）に加え、患者の血液を脱血するためのチ
ューブ先端が封止されたルーメンと、逆に患者へ血液を
送血するためのチューブ先端が解放されているルーメン
とを備え、目的に合わせて各ルーメンに通ずる側孔が空
けられていることを特徴とする２バルーンカテーテル。1. A surface for blocking blood flow of a patient.
In a flexible tube provided with two balloons, in addition to two airway lumens (lumens) for sending gas, liquid, and the like to the balloons, a lumen in which a tube tip for removing blood from a patient is sealed. And, on the contrary, a lumen in which the tip of a tube for sending blood to the patient is open, and a side hole communicating with each lumen is provided according to the purpose.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9202938A JPH1147265A (en) | 1997-07-29 | 1997-07-29 | Two baloon catheter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9202938A JPH1147265A (en) | 1997-07-29 | 1997-07-29 | Two baloon catheter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH1147265A true JPH1147265A (en) | 1999-02-23 |
Family
ID=16465657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9202938A Pending JPH1147265A (en) | 1997-07-29 | 1997-07-29 | Two baloon catheter |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH1147265A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001340466A (en) * | 2000-05-30 | 2001-12-11 | Unitika Ltd | Double lumen catheter |
| JP2005040606A (en) * | 2003-07-18 | 2005-02-17 | Cordis Corp | Hepatic perfusion separation method |
| JP2012200573A (en) * | 2011-03-28 | 2012-10-22 | Kobe Univ | Two-balloon catheter |
| JP2013509941A (en) * | 2009-11-09 | 2013-03-21 | デルキャス システムズ、インク． | System and method for treating organ disease while maintaining homeostasis by local administration of therapeutic agent |
| JP2013513436A (en) * | 2009-12-09 | 2013-04-22 | オスプレー メディカル インコーポレイテッド | Catheter system with distal and proximal collection ports |
| CN110559498A (en) * | 2019-10-14 | 2019-12-13 | 南京医科大学附属逸夫医院 | Novel dialysis catheter with water bag |
-
1997
- 1997-07-29 JP JP9202938A patent/JPH1147265A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001340466A (en) * | 2000-05-30 | 2001-12-11 | Unitika Ltd | Double lumen catheter |
| JP2005040606A (en) * | 2003-07-18 | 2005-02-17 | Cordis Corp | Hepatic perfusion separation method |
| JP2013509941A (en) * | 2009-11-09 | 2013-03-21 | デルキャス システムズ、インク． | System and method for treating organ disease while maintaining homeostasis by local administration of therapeutic agent |
| JP2013513436A (en) * | 2009-12-09 | 2013-04-22 | オスプレー メディカル インコーポレイテッド | Catheter system with distal and proximal collection ports |
| JP2012200573A (en) * | 2011-03-28 | 2012-10-22 | Kobe Univ | Two-balloon catheter |
| CN110559498A (en) * | 2019-10-14 | 2019-12-13 | 南京医科大学附属逸夫医院 | Novel dialysis catheter with water bag |
| CN110559498B (en) * | 2019-10-14 | 2024-05-31 | 南京医科大学附属逸夫医院 | Novel dialysis catheter with water bag |
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