JPH1147139A - Surgical device - Google Patents
Surgical deviceInfo
- Publication number
- JPH1147139A JPH1147139A JP9204299A JP20429997A JPH1147139A JP H1147139 A JPH1147139 A JP H1147139A JP 9204299 A JP9204299 A JP 9204299A JP 20429997 A JP20429997 A JP 20429997A JP H1147139 A JPH1147139 A JP H1147139A
- Authority
- JP
- Japan
- Prior art keywords
- light
- suction tube
- fiber
- living body
- hemoglobin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
Description
【０００１】[0001]
【発明の属する技術分野】本発明は、吸引管などのよう
に生体内に挿入される施術用の手術器具を有する手術装
置に係り、特に、例えば、酸素代謝機能のような生体に
おける代謝機能を測る機能を備え、測定された代謝機能
情報で病変部を確認しながら、施術できるようにした手
術装置に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a surgical apparatus having a surgical instrument inserted into a living body, such as a suction tube, and more particularly to a metabolic function such as an oxygen metabolizing function in a living body. The present invention relates to a surgical apparatus having a measuring function and capable of performing an operation while confirming a lesioned part based on measured metabolic function information.
【０００２】[0002]
【従来の技術】脳神経外科の分野では、例えば、脳内に
腫瘍が見付かった場合、開頭し、吸引管などの手術器具
を腫瘍の位置まで挿入し、腫瘍を吸引するなどの処置が
行なわれる。この場合、正常な脳機能や構造物への影響
を最小限にして腫瘍などの病変部のみを除去することが
肝要であり、そのためには病変部の位置を確認し、その
位置に吸引管の先端部を位置させる必要がある。この病
変部位置の確認ないし特定、ならびに、吸引管が腫瘍の
位置にあるかどうかは、一般に、事前にＸ線ＣＴ装置、
ＭＲＩ装置などの画像撮影装置で撮影された画像より経
験的に判断するか、または、吸引管に位置検出用のセン
サーを設け、画像撮影装置で撮影された画像上に吸引管
の位置を表示することにより、腫瘍位置を確認し、処置
が行なわれる。2. Description of the Related Art In the field of neurosurgery, for example, when a tumor is found in the brain, procedures such as craniotomy, insertion of a surgical instrument such as a suction tube to the position of the tumor, and suction of the tumor are performed. In this case, it is imperative that only the affected area such as a tumor be removed while minimizing the effect on normal brain functions and structures. The tip must be located. Confirmation or identification of the lesion location and whether the suction tube is at the position of the tumor are generally determined in advance by an X-ray CT apparatus,
Judging empirically from an image captured by an image capturing apparatus such as an MRI apparatus, or providing a sensor for position detection on the suction pipe and displaying the position of the suction pipe on an image captured by the image capturing apparatus Thereby, the position of the tumor is confirmed, and the treatment is performed.
【０００３】[0003]
【発明が解決しようとする課題】しかしながら、前者の
位置の確認手法では、経験と熟練を要し、また、後者の
手法では、画像上に吸引管などの手術器具の位置を表示
する手段を必要とすると共に、Ｘ線ＣＴ装置などの画像
撮影装置の固有の空間座標（ＣＴ座標）と手術器具の位
置表示装置の実空間座標（手術器具の位置検出手段を基
準とする座標系）との対応付け（キャリブレーション）
が正確に行なわれていないと、手術器具の位置を正確に
表示できず、また、キャリブレーションに熟練と時間を
要するという問題がある。また、キャリブレーションが
正確に行なえ、吸引管を画像上で特定した腫瘍位置に位
置させたとしても、それが腫瘍であるとの保証はなく、
前者の手法も含め、最終的には、術者の感と経験に頼ら
ざるを得ないのが実情である。However, the former position confirmation method requires experience and skill, and the latter method requires means for displaying the position of a surgical instrument such as a suction tube on an image. And the correspondence between the unique spatial coordinates (CT coordinates) of an image capturing device such as an X-ray CT device and the real space coordinates of the surgical instrument position display device (coordinate system based on the surgical instrument position detecting means). Attaching (calibration)
If the calibration is not performed accurately, there is a problem that the position of the surgical instrument cannot be accurately displayed, and that the calibration requires skill and time. In addition, even if calibration can be performed accurately and the suction tube is positioned at the tumor position specified on the image, there is no guarantee that it is a tumor,
Ultimately, including the former method, it is necessary to rely on the surgeon's feelings and experience.
【０００４】本発明は、上記の事情に鑑み、体内に挿入
された手術器具による施術部位の組織の代謝機能情報を
測定でき、測定された情報により、有効かつ安全に手術
が行な得る手術装置を提供することを目的とする。The present invention has been made in view of the above circumstances, and provides a surgical apparatus capable of measuring metabolic function information of a tissue at a treatment site by a surgical instrument inserted into a body, and performing an effective and safe operation based on the measured information. The purpose is to provide.
【０００５】[0005]
【課題を解決するための手段】上記目的を達成するため
に、本発明の手術装置は、施術部位に測定光を投光する
投光用ファイバと生体からの反射光を受光する受光用フ
ァイバとを生体内に挿入される手術器具に配設し、受光
用ファイバで受光された反射光を光検出手段で光電変換
して光検出信号とし、光検出信号に基づき代謝機能情報
演算手段で生体組織の代謝機能情報を求め、それを表示
手段に表示するようにしたことを特徴としている。In order to achieve the above object, a surgical apparatus according to the present invention comprises a light emitting fiber for projecting measurement light to a treatment site and a light receiving fiber for receiving reflected light from a living body. Is disposed on a surgical instrument to be inserted into a living body, and the reflected light received by the light-receiving fiber is photoelectrically converted by a light detection means into a light detection signal. Is characterized in that metabolic function information is obtained and displayed on display means.
【０００６】このような構成によれば、生体内に挿入さ
れる吸引管などの手術器具、例えば、吸引管の先端部か
ら投光用ファイバによって測定光が投光されると共に、
吸引管の先端部で受光用ファイバにより反射光が受光さ
れ光検出手段へ導かれて光電変換され、光検出手段から
の光検出信号に基づき代謝機能情報演算手段が生体組織
の代謝機能情報を求出し、それを表示手段が表示する。According to such a configuration, the measuring light is projected from the surgical instrument such as the suction tube inserted into the living body, for example, the tip of the suction tube by the light emitting fiber, and
The reflected light is received by the light-receiving fiber at the tip of the suction tube, guided to the light detecting means, and subjected to photoelectric conversion. Based on the light detection signal from the light detecting means, the metabolic function information calculating means obtains metabolic function information of the living tissue. And displays it on the display means.
【０００７】代謝情報としては、人体（生体）の酸素代
謝情報を測るものがあり、血液中の酸素化ヘモグロビ
ン、ないし、脱酸素化ヘモグロビンの量的経時変化など
が測られる。酸素代謝機能測定装置の測定原理は、赤外
領域から近赤外領域の波長を有する光は、生体組織に対
する透過性を有するのに加え、ヘモグロビン等の酸素代
謝を司る物質に対する吸光性を有するとともに酸素代謝
を司る物質の酸素結合状態により吸収スペクトルが変化
するという性質を利用するものである。As metabolic information, there is information for measuring oxygen metabolism information of the human body (living body). For example, quantitative changes over time of oxygenated hemoglobin or deoxygenated hemoglobin in blood are measured. The measurement principle of the oxygen metabolism function measurement device is that light having a wavelength in the infrared region to the near-infrared region has not only permeability to living tissue but also absorbability to hemoglobin and other substances that control oxygen metabolism. It utilizes the property that the absorption spectrum changes depending on the oxygen binding state of the substance that controls oxygen metabolism.
【０００８】例えば、脳内の正常組織と腫瘍組織では代
謝状態、すなわち、酸素摂取量が異なるので（腫瘍中心
では酸素摂取量が多く、腫瘍辺縁部では酸素摂取量が少
ない）吸引管を脳内に挿入することにより、吸引管先端
部の酸素ヘモグロビンや脱酸素ヘモグロビンの量を測定
できる。これにより、組織代謝機能情報を測定しながら
吸引管を挿入していくことが可能となり、吸引管先端部
が腫瘍組織内にあるか、または、正常組織内にあるかの
判定を行なうことができ、術者の経験によらず、有効か
つ安全に腫瘍の除去などの手術を適確に施行することが
できる。For example, the metabolic state, that is, the oxygen uptake is different between the normal tissue and the tumor tissue in the brain (the oxygen uptake is high at the center of the tumor and low at the tumor periphery). By inserting into the inside, the amount of oxygenated hemoglobin and deoxygenated hemoglobin at the tip of the suction tube can be measured. This makes it possible to insert the suction tube while measuring the tissue metabolic function information, and determine whether the tip of the suction tube is in the tumor tissue or in the normal tissue. In addition, surgery such as removal of a tumor can be performed accurately and accurately regardless of the surgeon's experience.
【０００９】[0009]
【発明の実施の形態】以下、本発明の一実施の形態を図
面を参照しながら説明する。図１は実施例に係る手術装
置の全体構成を示す図、図２は実施例装置の吸引管の構
成を示す模式図である。実施例の手術装置は、頭部に挿
入される吸引管１と、吸引管に配設された受光用ファイ
バで受光された反射光より酸素代謝機能を測定する酸素
代謝機能測定機構20を備えている。図１において、１は
頭部（脳）Ｍ内に挿入される吸引管で、図２に示すよう
に、吸引管先端１ａから測定光を脳に投光する投光用フ
ァイバ２と、吸引管先端１ａで脳から戻ってくる反射光
を受光する受光用ファイバ３とが配設されている。投光
用ファイバ２へは、レーザダイオードを使って光を出力
するレーザ光源部４から赤外領域から近赤外領域の波長
を有するレーザ光が供給され、このレーザ光が吸引管先
端１ａから脳に直に投射される。そして、脳で散乱反射
等して戻ってくる反射光は受光用ファイバ３で受光され
て、フォトマルチメーター（光検出手段）５へ導かれ、
ここで光電変換されて光検出信号として出力される。DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS An embodiment of the present invention will be described below with reference to the drawings. FIG. 1 is a view showing the overall configuration of a surgical apparatus according to an embodiment, and FIG. 2 is a schematic view showing the configuration of a suction tube of the apparatus of the embodiment. The surgical apparatus according to the embodiment includes a suction tube 1 inserted into the head, and an oxygen metabolism function measuring mechanism 20 for measuring an oxygen metabolism function from reflected light received by a light receiving fiber provided in the suction tube. I have. In FIG. 1, reference numeral 1 denotes a suction tube inserted into a head (brain) M. As shown in FIG. 2, a light emitting fiber 2 for projecting measurement light from the suction tube tip 1a to the brain, and a suction tube A light receiving fiber 3 for receiving the reflected light returning from the brain at the tip 1a is provided. A laser beam having a wavelength in an infrared region to a near infrared region is supplied from a laser light source unit 4 that outputs light using a laser diode to the light projecting fiber 2, and this laser beam is transmitted from the suction tube tip 1a to the brain. Directly projected to Then, the reflected light which is scattered and reflected by the brain and returned is received by the light receiving fiber 3 and guided to the photomultimeter (light detecting means) 5,
Here, it is photoelectrically converted and output as a light detection signal.
【００１０】この酸素代謝機能測定機構20は、赤外〜近
赤外の光が、生体組織に対する透過性を有するととも
に、図３に示すように、酸素代謝を司るヘモグロビンに
対する吸光性を有するのに加え、さらにヘモグロビンの
酸素結合状態により吸収スペクトルが変化するという性
質を有することを利用するものである。すなわち、各波
長での吸光度変化ΔＡと、酸素化（ＨｂＯ2 ）ヘモグロ
ビンと脱酸素化（Ｈｂ）ヘモグロビンの量的変化（初期
値からの変化量）は次の式（１）で示される。The oxygen metabolism function measuring mechanism 20 is designed to transmit infrared to near-infrared light, as shown in FIG. 3, while having a light-absorbing property for hemoglobin, which controls oxygen metabolism. In addition, it utilizes the fact that the absorption spectrum changes depending on the oxygen binding state of hemoglobin. That is, the change in absorbance ΔA at each wavelength and the quantitative change (change from the initial value) of oxygenated (HbO 2 ) hemoglobin and deoxygenated (Hb) hemoglobin are expressed by the following equation (1).
【００１１】 ΔＡ＝（μａ・ΔＨｂＯ2 ＋μｂ・ΔＨｂ）×ＭＰ …（１） 但し、μａはＨｂＯ2 のモル当たりの吸収係数、μｂは
Ｈｂのモル当たりの吸収係数、ΔＨｂＯ2 は酸素化（Ｈ
ｂＯ2 ）ヘモグロビンの変化量、ΔＨｂは脱酸素化（Ｈ
ｂＯ2 ）ヘモグロビンの変化量、ＭＰは光の平均経路長
である。ΔA = (μa · ΔHbO 2 + μb · ΔHb) × MP (1) where μa is the absorption coefficient per mole of HbO 2 , μb is the absorption coefficient per mole of Hb, and ΔHbO 2 is oxygenated (H
bO 2 ) Hemoglobin change, ΔHb is deoxygenated (H
bO 2 ) the amount of change in hemoglobin, MP is the average path length of light.
【００１２】上の式が測定波長の数だけ成立するので、
最低２つの波長での吸光度を測定すれば事足りる。ただ
実施例装置では３つの異なる波長での吸光度を測定する
構成となっている。３波長で測定した場合、最小２乗法
を適用して精度を高めることができる。なお、上の式
は、相対量を求める式であるが、もちろん絶対量を求め
るようにすることもできるのは言うまでもない。そし
て、実施例装置の場合、レーザ光源部４が波長の異なる
３つのレーザ光を順に投光用ファイバ２を通して脳に照
射する。３波長の具体例としては、ヘモグロビンの等吸
収点（８０５ｎｍ）は挟む３波長、つまり７８０ｎｍ，
８０５ｎｍ，８３０ｎｍが挙げられる。Since the above equation holds for the number of measurement wavelengths,
It is sufficient to measure the absorbance at at least two wavelengths. However, the apparatus of the embodiment is configured to measure the absorbance at three different wavelengths. When measuring at three wavelengths, the accuracy can be improved by applying the least squares method. The above equation is an equation for calculating a relative quantity, but it is needless to say that an absolute quantity can be obtained. In the case of the embodiment apparatus, the laser light source unit 4 irradiates the brain with three laser lights having different wavelengths sequentially through the light projecting fiber 2. As a specific example of the three wavelengths, the isosbestic point (805 nm) of hemoglobin is sandwiched by three wavelengths, that is, 780 nm,
805 nm and 830 nm.
【００１３】フォトマルチメーター５からの光検出信号
は、プリアンプ６で増幅されてから積分回路７で積分さ
れた後、ＡＤ変換器８でディジタル信号に変換された上
で、演算処理部（代謝機能情報演算部）９において上に
示した式（１）等に従う演算が行われ、酸素代謝機能デ
ータとして、酸素化（ＨｂＯ2 ）ヘモグロビンや脱酸素
化ヘモグロビン、あるいは、総ヘモグロビンの変化量や
絶対量などが算出されることになる。代謝機能情報演算
部９により得られる酸素化ヘモグロビンや脱酸素化ヘモ
グロビンあるいは総ヘモグロビンの経時的な変化量は、
表示手段としてのモニタ10やプリンタ11で連続的に表示
され、図４に示すようなグラフとして出力される。The photodetection signal from the photomultimeter 5 is amplified by a preamplifier 6, integrated by an integration circuit 7, converted to a digital signal by an AD converter 8, and then processed by an arithmetic processing unit (metabolism function). The information calculation unit 9 performs a calculation in accordance with the above equation (1) and the like, and as oxygen metabolism function data, changes or absolute amounts of oxygenated (HbO 2 ) hemoglobin, deoxygenated hemoglobin, or total hemoglobin Are calculated. The change with time of oxygenated hemoglobin, deoxygenated hemoglobin, or total hemoglobin obtained by the metabolic function information calculation unit 9 is as follows:
The image is continuously displayed on the monitor 10 or the printer 11 as a display means, and is output as a graph as shown in FIG.
【００１４】次に、以上の構成を有する実施例の吸引管
１を備えた手術装置の動作について説明する。被検体に
開けた小孔より吸引管１を頭部Ｍの中に挿入して、投光
用ファイバ２から７８０ｎｍ，８０５ｎｍ，８３０ｎｍ
の各波長のレーザ光を順に投光するとともに、受光用フ
ァイバ３で反射光を取り出して光検出信号を得て、この
光検出信号に基づき、代謝機能情報演算部９が、酸素化
ヘモグロビンや脱酸素化ヘモグロビンあるいは総ヘモグ
ロビンの変化量や絶対量などの中の必要なものを算出す
る。酸素代謝機能情報が測定される部位は、吸引管先端
１ａの投射光と受光用ファイバ間の距離、ファイバ端面
の向きによって決定されるので、例えば、吸引管先端部
の前方を測定できるように距離、位置を設定しておいた
場合、組織の酸素代謝情報を測定しながら吸引管１を挿
入していくことにより、挿入部の組織を識別することが
可能になり、吸引管１を腫瘍部位（病変部）に適確に挿
入して腫瘍などの病変部の除去など必要な処置が行え
る。Next, the operation of the surgical apparatus provided with the suction tube 1 of the embodiment having the above configuration will be described. The suction tube 1 is inserted into the head M through a small hole opened in the subject, and 780 nm, 805 nm, and 830 nm are emitted from the light emitting fiber 2.
Are sequentially emitted, and the reflected light is taken out by the light receiving fiber 3 to obtain a light detection signal. Based on the light detection signal, the metabolic function information calculation unit 9 causes the oxygenated hemoglobin or The necessary ones among the change amount and the absolute amount of oxygenated hemoglobin or total hemoglobin are calculated. The site where the oxygen metabolism function information is measured is determined by the distance between the projection light and the receiving fiber at the suction tube tip 1a and the orientation of the fiber end face. For example, the distance is set so that the front of the suction tube tip can be measured. When the position is set, by inserting the suction tube 1 while measuring the oxygen metabolism information of the tissue, it becomes possible to identify the tissue at the insertion portion, and the suction tube 1 is connected to the tumor site ( (Lesion) and can perform necessary treatments such as removal of a lesion such as a tumor by inserting it properly.
【００１５】なお、上記の実施例では、吸引管に投光用
ファイバと受光用ファイバを設けたが、内視鏡、カテー
テルなどの施術用の手術器具に取り付けてもよい。ま
た、実施例では、受光用ファイバは１チャンネルであっ
たが、投光用ファイバとの距離、向きの違う複数チャン
ネルの受光用ファイバを設けてもよい。このようにすれ
ば、広い領域での代謝情報を測定できるので、より安全
かつ適確に手術が施行できる。さらに、実施例では、頭
部の手術について説明したが、頭部以外、腹部などの手
術にも適用できる。また、実施例では、吸引管（手術器
具）の先端より投光し、反射光を先端で受光するように
手術器具に投光用ファイバと受光用ファイバを取り付け
たが、先端に限ることなく、要は、手術器具による施術
部に投光し、また、反射光を受光する位置に投光用ファ
イバ、受光用ファイバを取り付ければよい。さらにま
た、実施例では、酸素代謝機能を測定するものであった
が、酸素代謝機能以外の代謝機能を測定するものであっ
てもよい。In the above embodiment, the light emitting fiber and the light receiving fiber are provided in the suction tube, but they may be attached to a surgical instrument for treatment such as an endoscope or a catheter. In the embodiment, the light receiving fiber is one channel. However, light receiving fibers of a plurality of channels having different distances and directions from the light projecting fiber may be provided. In this way, metabolic information in a wide area can be measured, so that surgery can be performed more safely and accurately. Further, in the embodiment, the operation of the head has been described, but the present invention can be applied to operations of the abdomen and the like other than the head. Further, in the embodiment, the light emitting fiber and the light receiving fiber are attached to the surgical instrument so that light is projected from the distal end of the suction tube (surgical instrument) and the reflected light is received at the distal end. In short, it is only necessary to project light to a treatment part by a surgical instrument and attach a light projecting fiber and a light receiving fiber at a position where the reflected light is received. Furthermore, in the examples, the oxygen metabolism function is measured, but a metabolic function other than the oxygen metabolism function may be measured.
【００１６】[0016]
【発明の効果】本発明の手術装置によれば、生体内に挿
入された手術器具周囲の組織の代謝情報を正確に測定で
きるので、術者の経験によらず、病変部の除去などの手
術を有効かつ安全に、しかも適確に施行することができ
る。According to the surgical apparatus of the present invention, it is possible to accurately measure the metabolic information of the tissue around the surgical instrument inserted into the living body. Can be implemented effectively, safely, and accurately.
【図１】本発明の実施例を示すブロック図である。FIG. 1 is a block diagram showing an embodiment of the present invention.
【図２】実施例の吸引管の構成を示す模式図である。FIG. 2 is a schematic diagram illustrating a configuration of a suction tube according to an embodiment.
【図３】酸素化・脱酸素化ヘモグロビンの光吸収スペク
トルを示すグラフである。FIG. 3 is a graph showing a light absorption spectrum of oxygenated / deoxygenated hemoglobin.
【図４】実施例装置でモニタに表示される酸素代謝機能
データを示すグラフである。FIG. 4 is a graph showing oxygen metabolism function data displayed on a monitor in the example device.
１…吸引管 ２…投光用ファイ
バ ３…受光用ファイバ ４…レーザ光源部 ５…フォトマルチメーター ９…演算処理部
（代謝機能情報演算部） 10…モニタ 11…プリンタ 20…酸素代謝機能測定機構DESCRIPTION OF SYMBOLS 1 ... Suction tube 2 ... Light emitting fiber 3 ... Light receiving fiber 4 ... Laser light source unit 5 ... Photomultimeter 9 ... Operation processing unit (metabolism function information operation unit) 10 ... Monitor 11 ... Printer 20 ... Oxygen metabolism function measurement mechanism
Claims (1)
イバと生体からの反射光を受光する受光用ファイバとを
有する生体内に挿入される手術器具と、前記受光用ファ
イバで受光された反射光を光電変換して光検出信号を出
力する光検出手段と、光検出信号に基づき生体組織の代
謝機能情報を演算する代謝機能情報演算手段と、演算さ
れた代謝機能情報を表示する表示手段とよりなる代謝機
能測定機構とを備えていることを特徴とする手術装置。A surgical instrument inserted into a living body having a light projecting fiber for projecting measurement light from a distal end portion and a light receiving fiber for receiving light reflected from the living body; and a surgical instrument received by the light receiving fiber. Light detection means for photoelectrically converting the reflected light to output a light detection signal, metabolic function information calculating means for calculating metabolic function information of living tissue based on the light detection signal, and display for displaying the calculated metabolic function information A surgical apparatus comprising: a metabolic function measuring mechanism comprising a means.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9204299A JPH1147139A (en) | 1997-07-30 | 1997-07-30 | Surgical device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9204299A JPH1147139A (en) | 1997-07-30 | 1997-07-30 | Surgical device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH1147139A true JPH1147139A (en) | 1999-02-23 |
Family
ID=16488189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9204299A Pending JPH1147139A (en) | 1997-07-30 | 1997-07-30 | Surgical device |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH1147139A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005118135A (en) * | 2003-10-14 | 2005-05-12 | Olympus Corp | Drainage tube |
| JP2005118134A (en) * | 2003-10-14 | 2005-05-12 | Olympus Corp | Puncture needle and ultrasonic endoscope system |
| WO2011091439A2 (en) * | 2010-01-25 | 2011-07-28 | Oregon Health & Science University | Fiberoptic probe for measuring tissue oxygenation and method for using same |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61249460A (en) * | 1985-04-25 | 1986-11-06 | リチヤ−ド・エム・ドウイア− | Laser surgical apparatus |
| JPH0422353A (en) * | 1990-05-16 | 1992-01-27 | Olympus Optical Co Ltd | Thrombus dissolutive therapy device |
| JPH06205789A (en) * | 1993-01-13 | 1994-07-26 | S L T Japan:Kk | Operating device by laser beam |
| JPH09149894A (en) * | 1995-12-01 | 1997-06-10 | Hitachi Ltd | Living body input device and living body controller using optical living body measurement method |
-
1997
- 1997-07-30 JP JP9204299A patent/JPH1147139A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61249460A (en) * | 1985-04-25 | 1986-11-06 | リチヤ−ド・エム・ドウイア− | Laser surgical apparatus |
| JPH0422353A (en) * | 1990-05-16 | 1992-01-27 | Olympus Optical Co Ltd | Thrombus dissolutive therapy device |
| JPH06205789A (en) * | 1993-01-13 | 1994-07-26 | S L T Japan:Kk | Operating device by laser beam |
| JPH09149894A (en) * | 1995-12-01 | 1997-06-10 | Hitachi Ltd | Living body input device and living body controller using optical living body measurement method |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005118135A (en) * | 2003-10-14 | 2005-05-12 | Olympus Corp | Drainage tube |
| JP2005118134A (en) * | 2003-10-14 | 2005-05-12 | Olympus Corp | Puncture needle and ultrasonic endoscope system |
| JP4533615B2 (en) * | 2003-10-14 | 2010-09-01 | オリンパス株式会社 | Puncture needle and ultrasonic endoscope system |
| WO2011091439A2 (en) * | 2010-01-25 | 2011-07-28 | Oregon Health & Science University | Fiberoptic probe for measuring tissue oxygenation and method for using same |
| WO2011091439A3 (en) * | 2010-01-25 | 2011-11-17 | Oregon Health & Science University | Fiberoptic probe for measuring tissue oxygenation and method for using same |
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