JPH11188095A - Jet injector set - Google Patents

Abstract

PROBLEM TO BE SOLVED: To prevent the container for liquid medicine from being broken and to allow unified management of with a needle-less a injector and the container. SOLUTION: The set of spray type injector consists of a needle-less injector 1 and cap-shaped casing holder 2 in which space 8 for the vial and space 9 for setting the injector in formed. A vial is inserted and retained in the space 8. As the top 5 of the injector is tightly inserted into the space 9, the needle-less injector 1 can be connected with the casing holder 2. Because the vial is protected inside the space 8, breakage of the vial can be certainly prevented. It becomes possible to manage the injector 1 and the casing holder in one in as they are connected with each other while they are retained.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an injection-type injector set for subcutaneous injection, which reliably prevents damage to a drug solution container containing a drug solution to be injected and enables integrated management of a needleless syringe and a drug solution container. Related to the technology.

[0002]

2. Description of the Related Art Injection type needleless syringes for subcutaneous injection are configured to jet a chemical solution from a skin into a body without using a needle by jetting the chemical solution from a jet outlet provided at a tip of a syringe tip. It is a syringe that can be injected. This needleless syringe is almost painless and can easily inject a drug solution, so it is used not only in medical facilities, but also, for example, for diabetic patients to inject insulin themselves (self-injection) on a daily basis. .

[0003] In the case of the conventional injection subcutaneous injection method, since the syringe is a needleless syringe, when a drug solution is sucked into a syringe from a drug solution vial (drug container) in which a drug solution to be injected is placed, as shown in FIG. A special adapter 41 with a hollow needle member 42 is used. As shown in FIG.
1 is attached to the mouth of the drug solution vial 43 so that the hollow needle member 42 penetrates the rubber stopper 44 of the glass drug vial 43, and as shown in FIG.
Is inserted into the fitting recess 47 of the adapter 41 to connect the needleless syringe 45 to the adapter 41.

The piston 48 of the needleless syringe 45 is
Is lowered in the direction indicated by the arrow RA. Then, the drug solution in the drug needle vial 43 comes out of the fitting recess 47 of the adapter 41 through the passage 49 of the hollow needle member 42, and further passes through the jet outlet 50 of the syringe distal end portion 46. It goes into the syringe 45. When the required amount of the drug solution is sucked into the syringe, the needleless syringe 45 is removed from the adapter 41, and the syringe tip 46 of the needleless syringe 45 is applied to the injection point, and the drug solution is jetted. When the injection is completed, from the viewpoint of hygiene, the syringe tip 46 of the needleless syringe 45 is used.
Then, each of the fitting recesses 47 of the adapter 41 is covered with a dedicated cap (not shown) and stored in a separated state.

[0005]

However, the conventional injection-type subcutaneous injection system has the following two problems. The first problem is that a glass drug solution vial 43
However, since it is bare and supported only by the neck, if it hits an object during storage, it may be easily broken and all chemicals may be useless.

[0006] The second problem is that the needleless syringe 45 and the drug vial 43 (with the adapter 41) are stored separately. In the case of a diabetic patient, it is often necessary to hit insulin on the go. Therefore, the patient carries the needleless syringe 45 and the drug vial 43 and goes out. You may forget which one. In addition, it is complicated to cover the needleless syringe 45 and the adapter 41 with dedicated caps.

SUMMARY OF THE INVENTION In view of the above circumstances, the present invention can reliably prevent damage to a drug solution container containing a drug solution to be injected, and can always manage a needleless syringe and a drug solution container integrally. The task is to provide a set.

[0008]

In order to achieve the above object, the injection type syringe set of the needleless injector is provided with an injection type needleless injector provided with a jet injection port of an injection liquid at a tip end of the tip of the syringe, A container holder for loading and holding a drug solution container containing a drug solution to be injected, wherein the container holder includes a container housing chamber for accommodating the entire drug solution container and a syringe fitting chamber into which a syringe tip is fitted. It is arranged in such a manner that an opening for entering and exiting the drug solution container and an opening for entering and exiting the distal end of the syringe are respectively provided on the opposite side of the partition wall, and a lid is detachably attached to the opening on the container storage chamber side. In addition, in the container storage chamber, a hollow needle member for collecting a drug solution is protruded from the partition wall toward the opening for entering and exiting the drug solution container.ぴIn addition to the receiving surface provided on the partition wall for receiving and receiving, a small opening communicating with the hollow needle member is opened at a position matching the jet injection port corresponding to the receiving surface, and the tip of the syringe fits into the syringe. A coupling structure is provided between the needleless syringe and the container holder so that the needleless syringe and the container holder are separably connected to each other so that the protruding end of the syringe tip is pressed against the receiving surface by being fitted into the joint room. I have.

[Operation] Next, the operation when using the injection syringe set according to the present invention will be described. When using the injection-type injector set of the present invention, first, a drug solution container containing a drug solution to be injected is loaded and held in a container holder. That is, by removing the lid that closes the opening for entering and exiting the drug solution container in the container holding chamber of the container holder, with the plug material closing the mouth of the drug solution container facing the tip of the hollow needle member,
When the chemical solution container is put into the container accommodating chamber through the opening, and the lid is attached again, the medical solution container is loaded and held in the container holder. In the loaded state of the drug solution container, the hollow needle member penetrates the stopper of the drug solution container loaded in the container storage chamber and comes into direct contact with the drug solution. You don't have to worry about hitting directly.

[0010] On the other hand, the needleless syringe is placed in an integrated state by a connecting structure provided between the needleless syringe and the container holder except when actually performing subcutaneous injection. In a state where the needleless syringe is connected to the container holder, the tip of the syringe is tightly and closely contacted with a receiving surface provided on the partition wall of the syringe fitting chamber without any gap, and has a small opening communicating with the hollow needle member. The liquid is kept in a state where there is no leakage of the chemical liquid, which is in close contact with the jet injection port. As a result, as long as the drug solution container is loaded in the container storage room, the needleless syringe and the drug solution container will always be together except for a very short period of time when the actual subcutaneous injection is performed. When traveling, both the needleless syringe and the drug solution container are always carried together.

[0011] In performing a subcutaneous injection, when a drug solution is sucked into a syringe, only the operation of pulling down the piston of the needleless syringe is performed as usual. As the pressure in the syringe becomes negative due to the operation of lowering the piston, the drug solution in the drug solution container passes through the passage of the hollow needle member and passes through the small opening that opens to the receiving surface provided on the partition wall of the syringe fitting chamber. After that, it is sucked into the syringe from the jet outlet. When the required amount of drug solution can be aspirated, the needleless syringe is disconnected from the container holder by disconnecting the needleless syringe from the container holder, and the needle tip of the needleless syringe is applied to the injection point to jet the drug solution. . When the injection is completed, the needleless syringe and the container holder are reconnected, and the needleless syringe and the container holder are kept together.

[0012]

An embodiment of the present invention will be described below with reference to the drawings. FIG. 1 is a cross-sectional view showing the vicinity of the distal end of the needleless syringe of the injection syringe set of the embodiment and the container holder cut away, and FIG. 2 is a plan view showing the appearance of the needleless syringe of the injection syringe set of the embodiment. It is.

As shown in FIGS. 1 and 2, the injection-type injector set according to the embodiment includes a needleless injector 1 for jetting a chemical solution and a cap for holding a chemical vial (chemical solution container) containing a chemical solution to be injected. And a container holder 2 in a shape of a circle.

In the case of the needleless syringe 1, as shown in FIG.
An orifice 4 is provided at the tip end of an injection liquid chamber (cylinder chamber) 3 into which the sucked drug solution enters, and a jet outlet 6 having a diameter of about 150 μm is opened at the tip of the syringe tip 5. On the other hand, a piston 7 is provided in the injection solution chamber 3 so as to be capable of reciprocating sliding. The piston 7 is pulled down when sucking a drug solution, and conversely, when the drug solution is ejected, the piston 7 is pulled down. It has a chemical liquid ejecting structure similar to that of a normal needleless syringe that is rapidly pushed up.

When the piston 7 is lowered, the user grips the first grip GA shown in FIG. 2 and rotates the second grip GB to adjust the scale to a desired scale. To push up the piston 7, the release button BT at the end of the syringe is pressed. When the release button BT is pressed, the piston 7 is suddenly pushed up by the pressure of the compression spring or the pressure of the gas, and the liquid medicine in the injection liquid chamber 3 is jetted from the jet injection port 6 with a vigorous jet.

The container holder 2 has a container accommodating chamber 8 having an internal shape that can just accommodate the entire liquid medicine vial, and a syringe fitting chamber 9 having an internal shape into which the syringe tip 5 can be fitted.
Are disposed adjacent to each other with the partition wall 10 interposed therebetween.
The container housing chamber 8 and the syringe fitting chamber 9 are respectively provided with an opening 11 for access to the drug solution container or an opening 1 for access to the tip of the syringe.
2 is formed on the side opposite to the partition wall. A removable lid 22 is attached to the opening 11 on the container storage chamber side. The cover 22 is provided with a thread 22 provided on the inner peripheral surface thereof.
a and a screw connection structure composed of a screw thread 11 a provided on the outer peripheral surface of the opening 11. The opening 12 of the syringe fitting chamber 9 has a structure in which the distal end of the needleless syringe 1 is mounted and closed as described later, so a dedicated cover is not always necessary. 12 may be made occluded. Similarly,
You may comprise so that the front-end | tip part of the needleless syringe 1 may also be covered with a special cover.

In the container accommodating chamber 8, a hollow needle (hollow needle member) 13 for collecting a drug solution is vertically protruded from the partition wall 10 toward the opening 11 with the tip 13 a facing slightly, and is slightly shorter than the hollow needle 13. The air introduction hollow needle 14 is also vertically provided with the tip 14 a facing the opening 11 from the partition wall 10. The introduction of air from the hollow needle 14 is for balancing the pressure in the chemical vial with the atmospheric pressure. Of course, both hollow needles 13 and 14 have distal ends 13b and 14 from distal ends 13a and 14a.
Needless to say, it has pores penetrating along the longitudinal direction up to b.

In the syringe fitting chamber 9, a receiving surface 15 is provided at the end of the partition wall 10 to exactly receive the tip of the fitted syringe tip 5. The abutting portion of the partition wall 10 is formed of a rubber member 10a, and the elasticity of the rubber member 10a allows the protruding end of the syringe tip 5 and the receiving surface 15 to come into close contact with no gap.

Further, a small opening 16 communicating with the pore of the hollow needle 13 is opened at a position of the receiving surface 15 where the jet injection port 6 of the needleless syringe 1 matches. In the case of the embodiment, the end 13b of the hollow needle 13 is stopped at the position of the back surface 10b of the rubber member 10a, and the gap 17 between the end 13b of the hollow needle 13 and the small opening 16 is provided in the rubber member 10a. It is connected by. Therefore, the tip 5 of the syringe is placed on the receiving surface 15.
In a state in which the injection port 6 is in close contact with the hollow needle 13, the injection port 6 communicates with the tip 13a of the hollow needle 13 through the small hole 16 via the small hole 17 and the small hole of the hollow needle 13.

Further, the partition wall 10 is provided with a side chamber 18 which communicates with the outside air through a pore passage 19, and the distal end 14b of the hollow needle 14 is open and communicates with the side chamber 18. An open / close valve mechanism is provided in the side chamber 18 with a spherical valve body 20, a compression spring 21, and an inclined surface 18a on the side of the side chamber inlet.
Normally, the spherical valve element 20 is pushed by the compression spring 21 and the inclined surface 1
However, when the inside of the side chamber 18 has a negative pressure more than a certain level from the outside air side, the spherical valve body 20 is pushed inward and separates from the inclined surface 18a, and the pore passage 19 is closed. It is configured to open and allow outside air to flow into the side chamber 18 through the pore passage 19.

In addition, in the injection syringe set of the embodiment, the needleless syringe 1 and the container holder 2 are connected to the syringe tip 5.
Is screwed into the syringe fitting chamber 9 so that the protruding end of the syringe tip 5 is pressed against the receiving surface 15 so as to be separably connected. 2 are provided. That is, FIG.
As shown in the figure, a screw connection structure is provided by a screw thread 5a provided on the outer peripheral surface of the syringe tip 5 and a screw thread 9a provided on the opening inner peripheral surface of the syringe fitting chamber 9. When the tip 5 is screwed into the syringe fitting chamber 9, the injection tip 5 advances to the back of the syringe fitting chamber 9, and the tip of the syringe tip 5 is pressed against the receiving surface 15. If the syringeless syringe 1 and the container holder 2 are connected and the screws are loosened,
The injection tip 5 is retracted from the syringe fitting chamber 9 so that the needleless syringe 1 and the container holder 2 are separated.

The container holder 2 is preferably made of a transparent plastic such as an acrylic resin or a polycarbonate resin since the remaining amount of the liquid vial being loaded can be seen at a glance from the outside. The hollow needles 13 and 14 are exemplified by stainless steel needles and the like. Further, the receiving surface 15
Is preferably a latex (natural rubber) having excellent chemical resistance.

Next, the usage of the injection syringe set of the embodiment having the above-described configuration will be specifically described. First, a method of loading a chemical vial will be described.
As shown in FIG. 3 (a), the lid 22 of the container storage chamber 8 is removed, and as shown in FIG. 3 (b), the rubber stopper 31 closing the mouth of the chemical vial 30 is inserted into the hollow needle 13, The chemical vial 30 is pushed into the container housing 8 so that the hollow needles 13 and 14 are inserted into the rubber stopper 31 in the state of being directed toward the tips 13 a and 14 a of the 14. Then, FIG.
As shown in FIG.
Push 0 further. When the lid 22 cannot be screwed in, as shown in FIG. 4, at the same time as the lid 22 is attached, the liquid medicine vial 30 is loaded and held in a state in which the liquid vial 30 does not loosely fit in the container accommodating chamber 8.

When the liquid vial 30 is loaded, the tips 13a and 14a of the hollow needles 13 and 14 come into direct contact with the liquid LB, and the entire liquid vial 30 is placed in the container storage chamber 8.
And there is no concern that the chemical vial 30 hits an object.
After the drug solution vial 30 is loaded into the container storage chamber 8 (or before the drug solution vial 30 is loaded), the needleless syringe 1 is pushed until the protruding end of the syringe tip 5 is pressed against the receiving surface 15 as shown in FIG. Screw it into the syringe fitting chamber 9.

Next, a method of sucking the drug solution LB into the injection solution chamber 3 of the needleless syringe 1 will be described. In the state shown in FIG. 4, the second grip GB is rotated to match the scale indicating the desired suction amount. With the rotation of the second grip GB, the piston 7 is pulled down and the injection solution chamber 3 becomes a negative pressure, so that the drug solution LB in the drug solution vial 30 becomes hollow needle 13 → pore 1
7 → small opening 16 → injection liquid chamber 3 on the route of jet injection port 6
Introduced to.

When the liquid medicine LB is sucked from the vial 30 into the injection liquid chamber 3, the side chamber 18 becomes negative pressure correspondingly,
When the spherical valve element 20 is separated from the inclined surface 19a,
External air (air) is instantaneously introduced into the chemical vial 30 through the path from the side chamber 19 to the hollow needle 14, so that the internal pressure of the chemical vial 30 and the atmospheric pressure are in an equilibrium state. When the internal pressure of the chemical vial 30 and the atmospheric pressure are in an equilibrium state, the side chamber 18
, The spherical valve element 20 is inclined to the inclined surface 19a.
Again, the pore passage 19 is closed, and the introduction of outside air naturally stops.

Further, execution of subcutaneous injection will be described. As described above, the first grip GA of the needleless syringe 1 having sucked the required amount of the drug solution LB is grasped and rotated in the opposite direction to loosen the screw, and the needleless syringe 1 is separated from the container holder 2. When the tip 5 of the syringe 1 of the needleless syringe 1 is applied to the injection point and the release button BT is pressed, the piston 7 is pushed by the pressure of the compression spring or the pressure of the gas, and is pushed up rapidly to jet the chemical LB. It is injected from the injection port 6 and injected into the patient's body.

Next, how to store the injection syringe set of the embodiment will be described. After the injection, the first grip GA of the needleless syringe 1 is gripped, and the needleless syringe 1 is pushed until the protruding end of the syringe tip 5 is pressed against the receiving surface 15 as shown in FIG. Then, the needleless syringe 1 and the container holder 2 are returned to the connected state. After that, keep it as it is. The tip of the syringe tip 5 is the receiving surface 15
, The hermetic state is maintained, and there is no fear that the chemical solution LB leaks from the chemical solution vial 30. Also,
Each time an injection is made, the syringe tip 5 of the needleless syringe 1 is disinfected with absorbent cotton or the like.
5 is always kept clean. That is, the container holder 2 has not only the function of holding the drug solution vial but also the function of protecting the syringe tip 5 of the needleless syringe 1.

Accordingly, the needleless syringe 1 and the container holder 2 are integrally stored in an appropriate state. Even when the device is carried, the needleless syringe 1 and the container holder 2 are always stored without forgetting one of them. It will be carried as a set, and it can be said that it is particularly suitable for a case where insulin is routinely struck like a diabetic patient. In addition, chemical vial 3
If the container holder 2 is discarded when 0 becomes empty, it is sanitary and easy to handle. However, the container holder 2 may be used repeatedly.

The present invention is not limited to the above embodiment, but can be modified as follows. (1) In the container holder of the embodiment, a cushion material is stuck on the inner peripheral surface of the container accommodating chamber 8 and the back surface of the lid 22 so that the side surface and the bottom surface of the chemical vial are in direct contact with the cushion material, so that the vial is A configuration that is more difficult to break can be cited as a modification.

(2) In the case of the embodiment, the chemical solution container is a vial type, but the present invention is applicable even if the chemical solution container is a cartridge type.

(3) In the case of the injection type syringe set of the embodiment, the connection structure between the needleless syringe and the container holder is a screw connection structure, but a so-called one-touch type connection connection type by fitting a pin and a guide groove. A connection structure can be given as a modification.

[0033]

As described above, according to the injection-type injector set of the present invention, the entirety of the chemical solution container is always accommodated in the container holding chamber of the container holder, and there is no need to worry about the chemical solution container hitting an object. In addition to being able to reliably prevent breakage of the needle, a connection structure is provided between the needleless syringe and the container holder. Since the needleless syringe and the drug solution container are in a connected state and always present together, the needleless syringe and the drug solution container can always be integrally managed. Further, since the container holder also has the cap function of the needleless syringe, it is not necessary to remove the cap as compared with the case where the dedicated cap is used, and the operability is good.

[Brief description of the drawings]

FIG. 1 is a cross-sectional view illustrating a configuration of a main part of an injection syringe set according to an embodiment.

FIG. 2 is a plan view showing the appearance of a needleless syringe of the injection syringe set of the embodiment.

FIG. 3 is a cross-sectional view showing a sequence of loading a chemical vial into a container holder according to the embodiment.

FIG. 4 is a cross-sectional view showing a state in which a drug solution vial is loaded and held in the container holder of the embodiment.

FIG. 5 is a front view showing a conventional injection syringe adapter.

FIG. 6 is a front view showing a connection state between a conventional injection syringe adapter and a vial.

FIG. 7 is a front view showing a state of a conventional injection-type injector at the time of sucking a drug solution.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 ... Needleless syringe 2 ... Container holder 5 ... Syringe tip part 5a, 9a ... Thread 6 ... Jet injection port 8 ... Container accommodating chamber 9 ... Syringe fitting chamber 10 ... Partition wall 11, 12 ... Opening 13 ... For liquid medicine collection Hollow needle 15 ... receiving surface 16 ... small opening 22 ... lid 30 ... chemical vial KB ... chemical

Claims (1)

[Claims] An injection-type needleless syringe provided with a jet injection port for an injection liquid at a tip end of a tip of a syringe, and a container holder for loading and holding a drug solution container containing a drug solution to be injected. The container housing chamber for accommodating the entire medicinal solution container and the syringe fitting chamber in which the tip of the syringe fits are separated by a partition wall. Side, and a lid is removably attached to the opening on the container storage chamber side, and a hollow needle member for collecting the chemical liquid in the container storage chamber is used for entering and exiting the chemical liquid container from the partition wall. In the syringe fitting chamber, a receiving surface is provided on the partition wall for exactly receiving the protruding end of the fitted syringe distal end, and a jet jet impinging on the receiving surface is provided. In addition to the small opening communicating with the hollow needle member being open at the position matching the mouth, the tip of the syringe fits into the syringe fitting chamber, and the tip of the syringe tip is pressed against the receiving surface. A connection structure for detachably connecting the needleless syringe and the container holder as described above is provided between the needleless syringe and the container holder.