JPH10510181A - Adjustable vertebral body replacement - Google Patents

Adjustable vertebral body replacement

Info

Publication number
JPH10510181A
JPH10510181A JP8517672A JP51767296A JPH10510181A JP H10510181 A JPH10510181 A JP H10510181A JP 8517672 A JP8517672 A JP 8517672A JP 51767296 A JP51767296 A JP 51767296A JP H10510181 A JPH10510181 A JP H10510181A
Authority
JP
Japan
Prior art keywords
implant
vertebral
vertebral replacement
replacement implant
cylindrical portion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8517672A
Other languages
Japanese (ja)
Other versions
JP3732228B2 (en
Inventor
ラベ,ルイ−マレー
ボイド,ローレンス・エム
シュヴァリエ,ジャン−ルイ
モルオー,ジャン−シャルル
Original Assignee
ソファモーア・デインク・グループ・インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ソファモーア・デインク・グループ・インコーポレーテッド filed Critical ソファモーア・デインク・グループ・インコーポレーテッド
Priority claimed from US09/073,081 external-priority patent/US6344057B1/en
Publication of JPH10510181A publication Critical patent/JPH10510181A/en
Application granted granted Critical
Publication of JP3732228B2 publication Critical patent/JP3732228B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
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    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
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    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8061Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates specially adapted for particular bones
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Landscapes

  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
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  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
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  • Molecular Biology (AREA)
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  • Prostheses (AREA)
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  • Paper (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
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  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

A vertebral replacement implant (20) for interposition in a space left by one or more removed vertebrae between adjacent intact vertebrae, comprising : a replacement body (21) with opposite ends sized to span a portion of the space between the intact vertebrae, said replacement body having first threads defined thereon at each of said opposite ends ; and a pair of endplates (22) each having an end surface (23) for contacting a respective one of the intact vertebrae when the implant is interposed in the space between the intact vertebrae, each of said endplates including a cylindrical portion having second threads defined thereon configured to threadedly engage said first threads on said replacement body; and characterized in that each of said endplates (22) includes a flange (35) defining said end surface (36) and extending outwardly from said cylindrical portion (37), said flange (35) including an arm (14) projecting away from said cylindrical portion (37), said arm (14) having a free end configured to extend beyond the adjacent intact vertebrae for engagement to a longitudinal member (105) disposed along the length of the spinal column.

Description

【発明の詳細な説明】 可調節型の椎骨体代替物 発明の背景 本発明は、1つ又はより多くの椎骨体、及びその隣接する円板に代替するため のインプラントに関する。より具体的には、この椎骨体代替物は、前方アプロー チ法を通じて植え込むのに特に適している。 脊椎の損傷の治療は、7世紀後半における脊髄の損傷に対する最初に記録され た外科手術の日から著しく進歩している。その技術、器具及びインプラントは、 永年に亙って改良され、外傷、病気又は先天性疾患のために生ずる可能性のある 多数の脊椎の損傷及び変形により良く対応し得るようになっている。脊柱後弯症 という1つの種類の脊椎の変形は、椎骨体自体の破損に起因することが多い、身 体の前面方向に椎骨が脱出することを伴う。この破損は、椎骨体の破損、又は破 裂損傷のような外傷性の損傷、又は椎骨体内の腫瘍、或いは変性に起因する非外 傷性の変形の形態として生ずる可能性がある。 胸部、又は腰脊柱の後方弯曲症の治療は、特に、損傷した椎骨体の支持、又は 代替に伴うより重大な合併症の幾つかを防止するため、今日、前方アプローチ法 により最も良く行うことができる。後方弯曲症の殆どの治療において、脊椎を前 方から著しく再構成することが必要とされ、損傷した椎骨体を完全に除去するこ とが最も多い。典型的な前方アプローチ法において、椎骨体、及び2つの隣接す る椎骨円板の一部分、又は全体を剥離させる。次に、脊椎をその正確な方向に操 作するため、残るスペースを偏向させる。 多くの場合、そのスペースには破損した椎骨体の形状となる形状にて形成され ることが多い重合化可能なペースト、又は骨移植片が充填される。多くの場合、 腸骨から摘出した骨のような自己の骨を使用してそのスペースを塞ぐ。この重合 化可能なペーストは、PMMA骨接合剤を含むことができる。自然の椎骨体を除 去した後に残るキャビティを充填したならば、変形していない隣接する椎骨間の 相対的動きを防止するため、その椎骨の間に、骨合成器具を挿入する。この骨合 成器具は、胸部又は腰脊椎に加わる荷重を支持するため、椎骨柱を再安定させ、 また、骨移植材料が隣接する椎骨体と結合する可能性及びその速度を増すために 必須である。骨移植片及び材料が十分に堅固であるならば、その骨合成器具は、 通常、更なる機械的応力を受けることはない。 公知の骨合成器具は、その開示内容を引用して本明細書に加えた、ジーン・マ リエ・ローレイン(Jean-Marie Laurain)への米国特許第5,108,395号に記載さ れている。このシステムは、本出願の図1及び図2に図示されている。先ず、図 1を参照すると、損傷した椎骨V3は、破損した椎骨体C3を含むことが理解でき る。その損傷した椎骨V3とその隣接する円板D2、D3を除去し得るようにその 2つの無傷の椎骨V2、V4を架橋させるため内部のインプラント1が設けられて いる。前方インプラント1は、多数のスパイク3により無傷の椎骨体に係合する 一対のクランプ2を備えている。更に、これらのクランプ2は、ねじ穴11を貫 通して伸長する骨ねじ5、及びクランプの横突起8により所定位置に保たれてい る。また、該インプラント1は、無傷の椎骨の間を跨ぎ得る形態とされたプレー ト6も備えており、該プレート6は、その位置にて脊柱により生じた荷重を支持 するのに十分堅固である。 各クランプ2は、プレート6の各端部に設けられた対応する開口部14を貫通 して伸長する形態とされた突出するねじ付きポスト12を有している。ナット7 は、そのねじ付きポスト12に係合してプレート6をクランプ2の各々に固定し 得るようにされている。クランプ2の表面は、プレート6の各端部における対応 する切込み16に係合する切込み15を有しており、これにより、該プレートが クランプ各々に対して異なる方向角度となることを可能にする。クランプを健全 な椎骨体V2、V4に対して確実に固定すべく、別の骨ねじ5を受け入れる開口部 9がクランプのねじ付きポスト12に貫通するように形成されている。 上記の米国特許第5,108,395号に記載されたシステムの一つの重要な特徴は、 クランプ2の各々に切欠き18を形成することである。これらの切欠きは、2つ の椎骨V2、V4の間に偏向力を提供すべく使用される鉗子19の先端を受け入れ 得る形態とされている。図2に図示するように、クランプ2を対応する健全な椎 骨に固定したならば、該鉗子19を使用して偏向させ、骨移植片Gを配置するた めのスペースが得られるようにする。この骨移植片が所定位置に配置されたなら ば、上述した方法にて前方プレート6をクランプ2の各々に取り付けることがで きる。このプレートが所定位置に配置されたならば、偏向用の鉗子19を取り外 し、ナット7を締め付けて堅固な構造体を形成する。 上記の米国特許第5,108,395号、及び本出願の図1及び図2に図示した前方構 造体は、自己、又は同種の骨移植材料を使用して前方から固定する1つのシステ ムである。従来の骨移植材料に代えて、又はこれに加えて、隣接する椎骨の間に 介在された追加的な要素を使用するその他のインプラントも考案されている。か かる装置の1つは、ビエデルマン・モーテック・カンパニーが「ハームズ・ケー ジ)」として販売している、ハームズ等の米国特許第4,820,305号に記載された ものがある。この装置は隣接する椎骨の間の隙間に中空の円筒状のメッシュを挿 入し、メッシュの中空の内部に骨移植材料が配置されるものである。 ブランティガンへの米国特許第5,192,327号には多数の中空の楕円形のインプ ラント(その内部に骨移植材料が配置される)から成る、「ハームズ・ケージ」 と同様の装置が示されている。ケールの欧州特許第0,179,695号には、健全な椎 骨(その中に骨成長材料を植え込むことができる)の間を伸長する多数の通路を 有する堅固な不活性体が示されている。更に、このケールの欧州特許に記載され た装置は、骨ねじを受け入れる穴を有して、椎骨の間を跨ぐプレートを備えてい る。 椎体の代替に特に適したもう1つの型式のインプラント装置は、空の椎骨スペ ースを完全に占める略中実な構造体の構成要素を含む。これらの装置は、カッパ 等の米国特許第4,554,914号、ドッティの同第4,599,086号、オギルビエ等の同第 4,636,217号及びドーニィの同第5,147,404号に示されている。これらの装置の各 々には、インプラントを所定位置に保つべく健全な椎骨の端板に係合するスパイ ク又は同様の機構が設けられている。同様の構造体は、マクミラン等の米国特許 第5,062,850号に記載されているが、この装置は、軸方向に固定された椎骨体補 綴物の支持コラムの間に開いたスペースを有している。 上記の特許の各々において、インプラント装置は、その装置を挿入する前に健 全な椎骨を別個に偏向させる必要がある。以下の特許には、この装置を「現場」 で膨張させる幾つかの特徴を含む椎骨補綴物が示されている。例えば、メイン等 の米国特許第4,932,975号、及びバーバーの同第5,236,460号には、液圧流体を導 入することを通じて伸長、縮退する補綴物が示されている。レザイアンの米国特 許第4,401,112号、ウーの同第4,553,273号、及びダーの同第4,657,550号には、 ねじ付き構成部品を操作することで「現場」で膨張する装置が記載されている。 更に、レザイアンへの特許には、その構造体を補強するため反対側の健全な椎骨 に係合したスパイク付きのプレートを更に備える、この型式のターンバックル構 造体が示されている。 近年、脊椎に器具を取り付けるため、前方アプローチ法を採用することがより 顕著となっている。こうした前方アプローチ法を進めるとき、幾つかの従来の装 置の欠点を伴わずに、前方外科手術の有利な全ての点を備える椎骨代替物を提供 することが益々必要となる。上述した椎骨体代替物の各々には、一つ又はよく多 くの欠点がある。例えば、ある装置は健全な椎骨の間にて骨を合成する手段が存 在しない。こうした装置は、隣接する健全な椎骨の間にて骨が内部成長し、又は 骨移植片を配置することを容易にする特徴が存在しない。代替した椎骨の代わり に骨質量体を注入するならば、後方弯曲症をより恒久的に且つ安定的に矯正する ことが可能であることが認識される。このように、全ての椎骨代替物はかかる特 徴に対応し得るものでなければならない。その他の椎骨補綴物は、特定の椎骨の 解剖学的形態に対応し得るようインプラントの寸法を調節する手段を提供し得な い。更に、別の装置は、安定した構造体を提供し易くする何らかの補助的な固定 手段を備えていない。こうした必要性及び多くのその他の特徴の各々は、本発明 による椎骨体代替物により実現される。 発明の概要 本発明は、2つの完全な椎骨の間の椎骨を除去することにより形成されたスペ ース内にインプラントを固定するための椎骨代替用インプラント、及び組立体を 対象とするものである。一つの形態において、このインプラントは、完全な椎骨 の間のスペースの相当部分を占める寸法とされた肉厚の薄い円筒体を有している 。この円筒体は、中空であり、インプラントを植え込んだならば、骨の内部成長 を許容し得るように、内部と連通した、その円筒体の壁に形成された複数の穴を 有している。この円筒体の両端は、連続的なねじ部分(好ましくは、円筒体の外 面に設けられる)を有している。 本発明のインプラントは、補綴物を植え込んだとき、完全な椎骨の対向する1 つに対して方向決めされた面を有する一対の端板を更に備えている。これらの端 板の各々は、端面から伸長する円筒状部分を有しており、該円筒状部分は、円筒 体のねじ付き端部に係合するねじを有している。該端板のねじは、円筒状部分の 内方にあることが好ましい。一つの形態において、これらの端板は、それ自体が 中空であり、円筒体の中空の内部と隣接する完全な椎骨とを連通させる。これと 代替的に、本発明は、弱体な椎骨に対する追加の支持体を提供すべく、端板の端 面を隣接する椎骨に対して閉じ得るようにインプラントに端部キャップを追加す ることも可能である。 本発明のもう一つの特徴は、円筒体を端板の各々に対して固定し、インプラン トの3つの構成要素のかみ合うねじが緩むのを防止する手段を提供することであ る。一つの形態において、この固定手段は、止めねじを受け入れ得るようにねじ が形成された端板のねじ部分の穴を含む。端板のこの2つの穴に2つの止めねじ をねじ込んで、端板と係合した円筒体に対してクランプ止め圧力が付与され得る ようにすることが好ましい。 別の実施の形態において、この固定手段は、端板の圧着可能な円筒状部分とす る。一つの形態において、この円筒状部分は圧着切欠きが形成された環状リング を有している。この環状リングの周りに圧着力を付与すれば切欠きは狭くなり、 これにより円筒状部分の円周が小さくなって、円筒体のねじ付き部分の周りに緊 密に係合する。 本発明の別の形態は、除去した椎骨により形成されたスペースの外側を伸長す る長手方向部材にインプラントを接続する手段を提供することにある。この長手 方向部材は、隣接する完全な椎骨に公知の方法にて固定されたプレート、又はロ ッドとすることができる。この長手方向部材は、椎骨の代替用インプラントを挿 入するため完全な椎骨を偏向させ易くするために使用することが好ましい。 一つの実施の形態において、この接続手段は長手方向部材にクランプし得る形 態とされたクランプを有している。このクランプは、完全な椎骨の間に介在され たとき、その代替用インプラントに向けて方向決めされるねじを支持している。 このインプラントの円筒体は、接続ねじを受け入れるようにねじが形成された多 数の穴を有している。このクランプは、長手方向インプラントの長さに沿って摺 動し、円筒体の多数のねじ付き穴とねじを整合させ易くすることが好ましい。更 に、このクランプは、円形のシートを有し、ねじは、長手方向部材に関する該ね じの角度方向を変更することを許容し得るように丸形の頭部を有している。 別の実施の形態において、接続手段は、端板のフランジから伸長するアームを 備えている。このアームの自由端は、長手方向部材が貫通して伸長する開口部を 有している。止めねじがこの開口部を横断し、長手方向部材を端板の長手方向部 材に固定する。 本発明の一つの目的は、損傷し、又は疾患のある椎骨により形成されたスペー スを支持し得る形態とされた椎骨体代替用インプラントを提供することである。 一つの目的は、インプラントが介在される椎骨の高さ位置に対応して、インプラ ントの全長を変化させ得るように容易に調節可能であるインプラントを提供する ことである。本発明のインプラントの更に別の目的は、この長さの調節を可能に し、また、非係合状態となること、即ち、ねじが外れるのを防止すべく構成要素 を固定する手段を提供することである。 隣接する完全な椎骨の間にて脊柱の長さに沿って伸長する長手方向部材に対し て椎骨代替用インプラントを接続する手段を提供することにより、本発明の別の 目的が達成される。この長手方向部材は、除去した椎骨により形成されたスペー スを偏向させて、代替用インプラントの挿入を容易にするために使用することが できる。更に別の目的は、装置を取り付けた高さ位置の融着を促進すべく骨の成 長材料を収容することのできるインプラントを提供することである。 本発明の椎骨体の一つの利点は、完全な椎骨の間にて骨の成長材料が融着する のを待つ間に、脊柱の荷重を支持する堅固なインプラントを提供する点である。 更に別の利点は、椎骨の異なる高さ位置にてスペースに対応し得るようにインプ ラントを容易に調節し得ることである。 本発明の他の目的、及び利点は、本発明の以下の説明を添付図面及び請求の範 囲と共に参照することにより、理解することができる。 図面の説明 図1は、従来技術の米国特許第5,108,395号による脊柱の骨合成インプラント の分解斜視図である。 図2は、米国特許第5,108,395号の従来の装置と関係付けられたクランプを保 持しつつ、椎骨間に移植片を配置することを可能にする装置を追加した、図1の 一部分を示す図である。 図3は、本発明の一つの実施の形態による椎骨体の代替物組立体の分解斜視図 である。 図4は、図3に示した椎骨体代替物組立体と接続して使用される端板の端面図 である。 図5は、図3の椎骨体代替物組立体と共に使用される端板の側面図である。 図6は、図3に示した椎骨体代替物組立体と共に使用されるクランプ組立体の 1つの構成要素を示す分解斜視図である。 図7は、椎骨部分を跨ぐ細長のロッドと共に使用するのに特に適した、本発明 の別の実施の形態による椎骨体代替物組立体の側面図である。 図8は、完全な椎骨の上の所定の位置に組立体がある、図7に示した椎骨体代 替物組立体の端面図である。 図9は、細長いロッドに係合したときの図7に示した組立体の側面図である。 図10は、図7に示した椎骨体代替物組立体と共に使用される端板の斜視図で ある。 図11は、胸部脊柱における、図3に示した椎骨体代替物組立体と共に使用さ れる1つの特定の端板の端面図である。 好適な実施の形態の説明 本発明の原理の理解を容易にする目的にて、以下に、図面に示した実施の形態 に関して特定の用語を使用して説明する。しかしながら、これは、本発明の範囲 を何ら限定することを意図するものではなく、図示した装置の変形例及び更なる 改変例、及び図示した本発明の原理の更なる適用は、本発明が関係する技術分野 の当業者に通常、案出されるものであると理解する。 先ず、図3を参照すると、本発明の一つの実施の形態による椎骨体代替物組立 体20が図示されている。該組立体20は、全体として、ねじ付きの円筒体21 と、ねじ付きの端板22と、端部キャップ23とを備えている。また、端板22 の各々を円筒体21の対応する端部に固定する手段の一つの実施の形態としての 止めねじ24も設けられている。一つの具体的な実施の形態において、該止めね じ24は、締付けトルクの限界値に達したとき、ねじの頭がせん断する破断可能 な係止ねじである。かかる係止ねじは、1994年8月29日付けで出願された共同出 願の仏国特許出願第94 10 377号に開示されている。 このねじ付きの円筒体21は、中空のキャビティ26を画成する円筒状壁25 で形成されている。該キャビティは、自己又は同種の材料の形態とすることので きる骨合成材料を受け入れる形態とされている。該円筒状壁25には、該キャビ ティ26と連通した複数の穴28が設けられている。これらの穴は、骨又は組織 が内部成長し、インプラントの安定性を更に高める通路を提供する。該円筒状壁 25は、以下により詳細に説明するように、支持組立体55に係合し得る形態と されて、インプラントの略中間に形成された第二の複数のねじ穴29を有してい る。 該円筒体21の一つの重要な特徴において、該円筒状壁25の両端は外ねじ3 2に形成されている。一つの具体的な実施の形態において、ねじ32は、ねじ付 きの円筒体21の全長の大部分に亙って各他端から伸長し且つねじ付きの端板2 2に係合する形態とされている。端板の各々は、フランジ35を備えており、該 フランジは、隣接する完全な椎骨体の端板の略荷重支承領域を覆う形状をしてい ることが好ましい。円筒体37には、フランジ35が一体に形成され、該フラン ジ35は、端板22を切開した椎骨スペース内に配置したとき、ねじ付きの円筒 体21の方向に伸長する。端板の各々の円筒体37は、その内部に止めねじ24 を受け入れ得るようにした多数のねじ穴39を有している。 端板22の円筒体37及びフランジ35は貫通穴40を画成する。該穴40の 内面には、円筒体21の雄ねじ32とかみ合う形態とされた雌ねじ41が設けら れている。好適な実施の形態において、ねじ41は、円筒体37の少なくとも全 長に沿って伸長し、好ましくは、フランジ35内まで伸長するようにする。 端板22の更に詳細は、図4及び図5に見ることができる。図5に図示するよ うに、円筒体37には、脊柱前弯曲症の角度43を画成し得るようにフランジ3 5が一体に形成されている。この角度は、図1に示した椎骨V3のような損傷し た椎骨に代替する椎骨体代替物組立体20を使用することを可能にし、また、そ の高さ位置にて脊柱の通常の前方弯曲症の曲率を保つことを目的とするものであ る。フランジ35の端面36には、該フランジを貫通して伸長する導管化穴45 が設けられている。これらの穴45は、隣接する椎骨の間のスペースを導管化さ せる通路を提供することを目的としている。該端面36には、図7の実施の形態 に示したスパイク91のような4つのスパイクを設けることができる。これと代 替的に、端面36に形成されたねじ穴46に係合するねじ付きステム121を有 するスパイク120(図3)を設けることもできる。その何れの場合でも、スパ イク(91、120)は、隣接する椎骨の端板に貫入して、「現場」におけるイ ンプラントの所定位置を保つのに役立つ形態とされている。 該端面には、フランジ35を横断し且つ内部穴40の弦部分を跨ぐ取り付けス ロット47が更に設けられている。取り付けスロットの各々には、穴48が貫通 している。端板22の円筒体37には、取り付けスロット47の各穴48と整合 された取り付け切欠き49が設けられている。これらのスロット47、穴48及 び切欠き49は、本明細書に説明するように、端部キャップ23を支持する形態 とされている。図3を再度参照すると、該端部キャップ23は、端部キャップの 平坦な円形プレート52の弦部分を横断するように取り付けられた略矩形の支持 バー50を備えている。支持バー50の各端部には、外方に突出する突起51が ある。該突起51の各々は、対応する穴48内に受け入れられる寸法とされる一 方、支持バー50自体は、フランジ35の取り付けスロット47に嵌まり得る形 態とされている。更に、突起51の各々は、円筒体37の対応する取り付け切欠 き49内に便宜に摺動する。このようにして、特に、代替物体組立体が隣接する 完全な椎骨V2、V4の間に配置されたとき、端部キャップ23は所定位置に保持 される。 該端部キャップ23は、隣接する完全な椎骨の間にてインプラントに対する追 加的な支持体を提供する。隣接する椎骨の間及び代替物体を貫通するように骨が 成長することが望まれるならば、この端部キャップは省略してもよい。これと代 替的に、各端部キャップ23のプレート52は、椎骨の端板とねじ付きの円筒体 21の内部に配置された骨成長材料との間にて骨が内部成長するのを許容し得る ように穴を開けることもできる。好適な実施の形態において、端板は中実であり 、椎骨柱の長さに沿って荷重に対する最大の荷重支承機能を提供する状態で示し てある。 図示した実施の形態において、円筒状の代替物体に設けられたねじ32は雄ね じである一方、端板のねじ40は、雌ねじである。これと代替的に、端板の円筒 体37は、雄ねじを有し、円筒状の代替物体がキャビティ26内に雌ねじを有す るようにしてもよい。この後者の場合、円筒体の内径は、当然に端板の円筒体の 外径よりも僅かに大きくなる。 好適な実施の形態において、インプラント21を形成する円筒壁は、従来技術 の代替物体と比較したとき、比較的薄くすることができる。一つの特定の実施の 形態において、この壁の厚さは1mmである。インプラントにより支承される主 荷重は曲げ荷重ではなくて軸方向圧縮力であるため、肉厚の薄い円筒体が適当で あり、更に望ましくもある。 又、インプラント21は、組織の内部成長及び導管化を促進し、これにより、 融着後の構造体の安定性を高めるために多数の穴28、29を有することも好ま しい。一つの特定の実施の形態において、これらの複数の穴の全面積は、円筒体 21の表面積の少なくとも25%となる。 使用時、図1に示した椎骨V3のような損傷した椎骨を除去する。一つの実施 の形態において、図1、図2に示した内部インプラント1のクランプ2が図2に 示した方法にて完全な椎骨体と係合している。また、図2に示すように、鉗子1 0を使用して、完全な椎骨を偏向させて、椎骨代替物組立体20を植え込むのを 許容し得るようにすることができる。好適な方法において、椎骨の最適な高さを 設定し、ねじ付きの円筒体21及びねじ付きの端板22を共に取り付けてその適 正な高さが得られるようにする。具体的には、所望の高さが得られる迄、端部キ ャップの各々をねじ付きの円筒体21にねじ止めすることができる。 各端板のフランジ35の底端縁44が2つのねじ付き端板22の間で略同一方 向に方向決めされるようにすることが重要である。代替物組立体20は、これら の椎骨の端板に当接する2つの完全な椎骨の間に配置されるから、この方向は重 要である。最大の荷重支承機能を保つため、フランジ35、特に、端面36は、 端板が当接する脊柱体の形状となるようにし、また、その寸法は、完全な椎骨の 端板の面積を可能な限り広く占めるように設定される。 腰、胸部−腰及び胸部の高さ位置にて椎骨体の解剖学的相違に対応し得るよう に、かかる形状は3種類にて設けられることが好ましい。図4に示したフランジ 35の形態は胸部−腰脊椎骨に適用可能である。図11に示したフランジ35’ を胸部高さ位置にて植え込むために、より小さくより円形の形態とすることも可 能である。また、このフランジ35’は、フランジと脊髄索を収容する硬膜スペ ースとの間の隙間を増し得るように逃がし半径38を有するものとして図示され ている。この逃がし半径38は、端板のフランジの3種類の形状の全てに含ませ ることが好ましい。 一つの特定の実施の形態において、ねじ付き円筒体21の雄ねじ32は反対方 向に形成して、円筒体のみを回転させることにより、端板を共に引き寄せ又は分 離させることができるようにしてある。このように、円筒体を一方向に回転させ ると、各端部におけるねじ32が端部キャップを共に引き寄せる正確な方向に向 けて各端部キャップ23の雌ねじ41に係合する。これと代替的に、ねじ32の 方向は、各端部にて等しくし、各端部キャップを円筒体21の上まで反対方向に 個々にねじ込むことが必要であるようにしてもよい。この配置の不利益な点は、 端面36の下方端縁44の各々の適正な方向を保ちつつ、組立体20の全体の高 さを調節することがより困難となる点である。その1つの有利な点は、「現場」 にてこの組立体がそれ自体のねじが緩むことがない点である。 端板およびねじ付きの円筒体が正確な高さとなり得るよう適正な方向に係合し たならば、止めねじ24を端板22の円筒体37のねじ付き開口部39の適当な 開口部にねじ込み、止めねじ24がねじ付きの円筒体21と接触するように伸長 するようにする。止めねじ24(上述した破断可能な係止ねじとすることができ る)は、円筒体21にクランプ止め圧力を加えて、該円筒体を所定位置に保持す る。このように、止めねじ24は、構成要素を共に固定し且つ円筒体21が端板 22の何れかに関して回転するのを防止する手段を提供する。ねじ付きの円筒体 21の関係付けられた端部を確実に固定すべく、各端板23に止めねじが2つ使 用されることが好ましい。止めねじ24が本体21上で確実に保持されるように するため、ねじ付き円筒体の穴28は、止めねじ24よりも小径としてある。 このように、円筒体および端板をその適正な高さ寸法位置に固定したならば、 骨移植材料を端板の穴40及び円筒体21のキャビティ26内に挿入することが できる。これらの構成要素の内部が骨移植材料で完全に充填された後、突起51 が穴48を貫通して伸長し、支持バー50が各端板の取り付けスロット47を貫 通するように端部32を所定位置に配置する。次に、偏向させた椎骨V2、V4の 間に代替物組立体20を配置することができる。この組立体が適正な位置に配置 され、端板22の各々の端面36が椎骨の端板の上で適正に方向決めされたなら ば、偏向用鉗子19を除去し、この組立体20が2つの脊柱骨の間で所定位置に クランプ止めされるようにする。 代替物組立体20が完全な脊椎骨の間のその所定位置に移行し、又は摺動しな いことを更に確実にするため、支持組立体55を設けることも可能である。この 好適な実施の形態において、この支持組立体55は、図1及び図2に図示した従 来技術の前方インプラントシステムと共に使用されるクランプ2と係合する形態 とされている。また、この支持組立体55は、ダネック・メディカル・インコー ポレーテッドから販売されているZ−プレートATLのようなその他の前方プレ ート、又はソファモーアS.N.C.のCDホフ・システムのようなロッドシステ ムと共に使用することも可能である。 特に、支持組立体は、安定化プレート57を有しており、このプレートは、図 1に示した板6と同様の形態とすることができ且つそのプレートの端部の底面に 切込みを有するようにする。椎骨代替物体組立体20をプレート57に接続する 手段は、クランプ組立体59を備えており、該クランプ組立体は、プレート57 を確実に把持し、係止ねじ69を支持する。このクランプ組立体59は、プレー ト57を把持し且つ支持するためC字形の形状であることが好ましい一対のクラ ンプ半体60を有している。クランプ半体60の各々は、調節プレート62のね じ付きロッド63を受け入れる穴(図示せず)を有している。クランプ半体60 を安定化プレート57の周りにて共に引き寄せるためナット64がロッド63上 にねじ止めされる。 この調節プレート62の詳細は図6により明確に示されている。この調節プレ ートは、プレート62の面65から伸長するねじ付きロッド63を有している。 また、該プレート62は、円形の着座面68を有する貫通穴67を有している。 この貫通穴67内には、係止ねじ69の丸形の頭部70が受け入れられる。この 係止ねじ69は、ドライバ工具を受け入れるため、その頭部に六角形の凹所71 を有している。また、この係止ねじ69は、ねじ付きの円筒体21のねじ穴29 の1つに係合し得るようにされたねじ付き軸部73を有している。係止ねじ69 を所定位置に案内し易くするため、ねじ付き軸部73よりも小径の案内ハブ75 が設けられている。この係止ねじ69は、ねじの頭部70とねじ付き軸部73と の間に平滑な軸部74を有することが好ましい。 使用時クランプ半体60は安定化プレート57に一時的に取り付けるが、この 安定化プレート57にクランプ止めはされない。次に、この安定化プレート57 は、安全な椎骨体の各々にてクランプ2に係合させ且つ図1に示したナット7の ような対応するナットにより所定位置に固定することができる。このように、安 定化プレート57が偏向した椎骨の間に取り付けられた状態にて、偏向用鉗子1 9を除去し、脊柱の全荷重が代替物組立体20によって支承することができる。 偏向用鉗子を除去したならば、クランプ半体60は、プレート57の長さに沿っ て調節し、係止ねじ69がねじ付きの円筒体21のねじ穴29の適当な1つの穴 と整合されるようにすることができる。係止ねじ69の頭部70と調節プレート 62の円形の着座部68とが球状に接触することは、ねじ付き穴29に係合する のに必要な任意の角度を係止ねじがとることを可能にする。このように整合した とき、調節プレート62とねじ付きの円筒体21との間にて係止される迄、係止 ねじ69を1つの穴62内に容易にねじ込むことができる。この時点にて、ナッ ト64をねじ付きロッド63上に締め付けることにより、プレート57の上にて クランプ半体60を完全にクランプ止めすることができる。 本発明の別実施例において、椎骨体代替物組立体80は、細長の偏向ロッド、 又は圧縮ロッドに接続可能な形態とされている。この実施の形態において、該組 立体80は、円筒体21に螺着可能に係合する形態とされた両端板83を有して いる(この円筒体21は、全ての点にて、図3に関して上述した円筒体21と略 同一である)。この実施例において、該端板83は、フランジ85と、該端板か ら突き出る円筒体87とを有している。この円筒体87は、円筒体21の雄ねじ 32を受け入れ得るようにねじが形成されたねじ穴88を有している。従来の端 板の場合と同様に、該端板83は、フランジ85に形成された複数の導管化穴8 9を有している。フランジ85の端面86は、該端面から突き出した多数のスパ イク91を有している。これらのスパイクは隣接する椎骨体の端板に貫入して、 「現場」にてインプラントを所定の位置に保ち易くする形態とされている。 図7及び図8に示すように、該端板83は、インプラントを長手方向部材(ロ ッド105のような部材)に接続する手段の1つの構成要素である、フランジ8 5から突き出すアーム94を有している。該アーム94の自由端94aに隣接す る位置にはロッド穴95が形成されており、止めねじ穴96がアーム94の自由 端からこのロッド穴95を横断している。貫通して伸長するロッドをクランプ止 めする止めねじ98が止めねじの穴96内に係合するように設けられている。 この実施の形態において、代替物組立体80を使用する方法は、図8及び図9 に示されている。特に、該端板83は、スパイク91を介して適当な椎骨に係合 している。これらのプレートも特定の椎骨の高さ位置にて適当な脊髄の解剖学的 形態に対応し得る角度115を画成する形態とされている。骨ねじ108を介し て、完全な椎骨の各々には、偏向プレート107が取り付けられている。このプ レート107は、該板と一体に形成されたカラー109を有しており、このカラ ー109を偏向ロッド105が貫通している。また、該偏向ロッドは、端板83 のアーム94のロッド穴95の各々を貫通するように伸長している。ロッドが穴 の各々を貫通して伸長する状態にて、止めねじ98は、これらの端板を所定位置 に固定する。それぞれの椎骨内に取り付けられた偏向プレート107の各々のカ ラー109に係合できる、適正な形状にて形成された器具により、隣接する椎骨 を偏向させることができる。ロッド105を各カラー109の内部に固定するた め止めねじ(図示せず)を設けることができる。 図7、図9及び図10を参照しつつ、端板をねじ付きの円筒体に固定する方法 について説明する。特に、端板83に、具体的には、端板の円筒体87には、固 定手段(円筒体の直径の周りで圧着溝100の形態とされている)が設けられて いる。この円筒体の両側部には、溝100内に圧着切欠き101が形成されてい る。要するに、この圧着切欠きは溝100の外周における空隙である。この圧着 切欠きは、圧着溝100の全周を把持する適当な把持工具によって閉じることの できる空隙を提供する。この圧着工具を締め付けると、溝が共に矢印102の方 向に動くとき、これらの切欠き101は閉じる。この圧着の形態は、端板をねじ 付きの円筒体に固定する止めねじ24(先の実施の形態に関して開示したねじ) に代替するものであることが理解できる。 本発明は、図面に図示し且つ上記の説明にて詳細に説明したが、これは、単に 一例にしか過ぎず、本発明の特徴を限定するものではなく、本発明に属する全て の変更及び改変例は、保護の対象を含むることを望むものであることを理解すべ きである。DETAILED DESCRIPTION OF THE INVENTION Adjustable Vertebral Body Replacement Background of the Invention The present invention relates to an implant for replacing one or more vertebral bodies and their adjacent discs. More specifically, the vertebral body replacement is particularly suitable for implantation through an anterior approach. The treatment of spinal injury has advanced significantly since the first recorded surgical day for spinal cord injury in the late 7th century. The techniques, instruments and implants have been improved over the years to better cope with the numerous spinal injuries and deformations that can occur due to trauma, disease or congenital disease. One type of spinal deformity, kyphosis, involves the prolapse of the vertebrae in the frontal direction of the body, often resulting from damage to the vertebral body itself. This failure can occur as a form of traumatic injury, such as a vertebral body fracture or rupture injury, or a non-traumatic deformation due to a tumor or degeneration in the vertebral body. Treatment of thoracic or lumbar spine kyphosis today is best done with an anterior approach today, especially to prevent some of the more serious complications associated with supporting or replacing a damaged vertebral body. it can. In most treatments for kyphosis, significant reconstruction of the spine from the anterior is required, most often with complete removal of the damaged vertebral body. In a typical anterior approach, the vertebral body and part or all of two adjacent vertebral discs are ablated. The remaining space is then deflected to steer the spine in its correct orientation. In many cases, the space is filled with a polymerizable paste or bone graft, often formed in the shape of a broken vertebral body. Often, the space is filled with self-bones, such as bones removed from the iliac bone. The polymerizable paste may include a PMMA bone cement. Once the cavity remaining after removal of the natural vertebral body has been filled, a osteosynthesis device is inserted between adjacent vertebrae that are not deformed to prevent relative movement between the vertebrae. This osteosynthesis device is essential for restoring the vertebral column to support loads on the thoracic or lumbar spine, and for increasing the likelihood and speed of bone graft material bonding with adjacent vertebral bodies. . If the bone graft and the material are sufficiently rigid, the osteosynthesis device will not normally experience additional mechanical stress. Known osteosynthesis devices are described in US Pat. No. 5,108,395 to Jean-Marie Laurain, the disclosure of which is incorporated herein by reference. This system is illustrated in FIGS. 1 and 2 of the present application. Referring first to FIG. 1, a damaged vertebra V Three Is the damaged vertebral body C Three Can be understood. The damaged vertebra V Three And its adjacent disk D Two , D Three The two intact vertebrae V so that the Two , V Four An internal implant 1 is provided for cross-linking. The anterior implant 1 comprises a pair of clamps 2 which engage an intact vertebral body with a number of spikes 3. Furthermore, these clamps 2 are held in place by bone screws 5 extending through screw holes 11 and lateral projections 8 of the clamp. The implant 1 also includes a plate 6 configured to span between intact vertebrae, the plate 6 being rigid enough to support the load generated by the spine at that location. Each clamp 2 has a projecting threaded post 12 configured to extend through a corresponding opening 14 at each end of the plate 6. The nut 7 is adapted to engage its threaded post 12 to secure the plate 6 to each of the clamps 2. The surface of the clamp 2 has a notch 15 which engages a corresponding notch 16 at each end of the plate 6, thereby allowing the plate to be at a different directional angle to each of the clamps. . Clamp the healthy vertebral body V Two , V Four An opening 9 for receiving another bone screw 5 is formed to pass through the threaded post 12 of the clamp in order to ensure a secure fixation. One important feature of the system described in the above-mentioned U.S. Pat. No. 5,108,395 is that a notch 18 is formed in each of the clamps 2. These notches are two vertebrae V Two , V Four Between the forceps 19 used to provide a biasing force between the forceps. Once the clamp 2 has been secured to the corresponding healthy vertebra, as shown in FIG. 2, the forceps 19 are used to deflect and provide space for placement of the bone graft G. Once the bone graft is in place, the anterior plate 6 can be attached to each of the clamps 2 in the manner described above. Once the plate is in place, the deflecting forceps 19 are removed and the nut 7 is tightened to form a solid structure. The anterior structure illustrated in the above-mentioned U.S. Pat. No. 5,108,395 and FIGS. 1 and 2 of the present application is one system for anterior fixation using self or similar bone graft material. Other implants have been devised which use additional elements interposed between adjacent vertebrae in place of or in addition to conventional bone graft materials. One such device is described in U.S. Pat. No. 4,820,305 to Harms et al., Sold by Biederman Motech Company as "Harms Cage". This device inserts a hollow cylindrical mesh into the gap between adjacent vertebrae and places the bone graft material inside the hollow of the mesh. U.S. Pat. No. 5,192,327 to Brantigan shows a device similar to the "Herms Cage", consisting of a number of hollow elliptical implants with bone graft material disposed therein. Kale's EP 0,179,695 shows a rigid inert body having multiple passages extending between healthy vertebrae, into which bone growth material can be implanted. In addition, the device described in Kale's European patent includes a plate that spans between the vertebrae with holes for receiving bone screws. Another type of implant device that is particularly suitable for vertebral body replacement includes components of a substantially solid structure that completely occupies empty vertebral space. These devices are shown in U.S. Patent Nos. 4,554,914 to Kappa et al., 4,599,086 to Dotti, 4,636,217 to Ogilvie et al., And 5,147,404 to Dorney. Each of these devices is provided with a spike or similar mechanism that engages a healthy vertebral endplate to keep the implant in place. A similar structure is described in U.S. Pat. No. 5,062,850 to MacMillan et al., Which has an open space between the support columns of the axially fixed vertebral body prosthesis. In each of the above patents, the implant device must separately deflect the healthy vertebrae before inserting the device. The following patent shows a vertebral prosthesis that includes several features that cause the device to expand "in situ". For example, U.S. Pat. No. 4,932,975 to Mein et al. And U.S. Pat. No. 5,236,460 to Barber show prostheses that expand and contract through the introduction of hydraulic fluid. U.S. Pat. No. 4,401,112 to Lezian, U.S. Pat. No. 4,553,273 to Wu, and U.S. Pat. No. 4,657,550 to U.S. Pat. Further, the patent to Rezian shows a turnbuckle structure of this type which further comprises a plate with spikes engaged with the opposite healthy vertebra to reinforce the structure. In recent years, the use of an anterior approach has become more prominent for attaching instruments to the spine. As one proceeds with such an anterior approach, there is an increasing need to provide a vertebral replacement with all the advantages of anterior surgery without the disadvantages of some conventional devices. Each of the vertebral body substitutes described above has one or more disadvantages. For example, some devices do not have a means to synthesize bone between healthy vertebrae. Such devices do not have features that facilitate bone ingrowth or placement of bone grafts between adjacent healthy vertebrae. It will be appreciated that injecting a bone mass in place of a replacement vertebra can more permanently and stably correct kyphosis. As such, all vertebral replacements must be able to accommodate such features. Other vertebral prostheses cannot provide a means to adjust the size of the implant to accommodate a particular vertebral anatomy. Further, other devices do not include any additional securing means that facilitate providing a stable structure. Each of these needs and many other features are realized by a vertebral body replacement according to the present invention. SUMMARY OF THE INVENTION The present invention is directed to a vertebral replacement implant and assembly for securing an implant in a space formed by removing a vertebra between two complete vertebrae. In one form, the implant has a thin walled cylinder sized to occupy a substantial portion of the space between complete vertebrae. The cylinder is hollow and has a plurality of holes formed in the wall of the cylinder that communicate with the interior so as to allow for bone ingrowth once the implant is implanted. Both ends of the cylinder have a continuous threaded portion (preferably provided on the outer surface of the cylinder). The implant of the present invention further comprises a pair of end plates having surfaces oriented with respect to the opposite one of the complete vertebra when the prosthesis is implanted. Each of these end plates has a cylindrical portion extending from an end face, the cylindrical portion having a thread engaging a threaded end of the cylinder. Preferably, the screws of the end plate are inside the cylindrical part. In one form, these end plates are hollow in themselves, providing communication between the hollow interior of the cylinder and the adjacent complete vertebra. Alternatively, the present invention can add an end cap to the implant so that the end face of the endplate can be closed against the adjacent vertebra to provide additional support for weak vertebrae. is there. Another feature of the present invention is that it provides a means of securing the cylinder to each of the end plates and preventing loosening of the mating screws of the three components of the implant. In one form, the securing means includes a hole in a threaded portion of the end plate that is threaded to accept a set screw. Preferably, two set screws are screwed into these two holes in the end plate so that clamping pressure can be applied to the cylinder engaged with the end plate. In another embodiment, the fixing means is a crimpable cylindrical portion of the end plate. In one form, the cylindrical portion has an annular ring with a crimp notch. Applying a crimping force around the annular ring narrows the notch, thereby reducing the circumference of the cylindrical portion and tightly engaging the threaded portion of the cylindrical body. Another aspect of the invention is to provide a means for connecting the implant to a longitudinal member that extends outside the space created by the removed vertebra. The longitudinal member may be a plate or rod secured in a known manner to the adjacent complete vertebra. This longitudinal member is preferably used to facilitate deflection of the complete vertebra to insert a vertebral replacement implant. In one embodiment, the connection means has a clamp configured to be clamped to the longitudinal member. The clamp supports a screw that is oriented toward the replacement implant when interposed between the complete vertebrae. The cylinder of the implant has a number of holes threaded to receive connecting screws. The clamp preferably slides along the length of the longitudinal implant to facilitate alignment of the thread with a number of threaded holes in the cylinder. Further, the clamp has a circular seat and the screw has a round head so as to allow changing the angular orientation of the screw with respect to the longitudinal member. In another embodiment, the connection means comprises an arm extending from a flange of the end plate. The free end of the arm has an opening through which the longitudinal member extends. A set screw traverses this opening and secures the longitudinal member to the longitudinal member of the end plate. It is an object of the present invention to provide a vertebral body replacement implant configured to support the space formed by a damaged or diseased vertebra. One object is to provide an implant that is easily adjustable so that the overall length of the implant can be varied, depending on the height position of the vertebra where the implant is interposed. It is a further object of the implant of the present invention to allow this length adjustment and to provide a means for securing the components so as to be disengaged, i.e., not unscrewed. It is. Another object of the present invention is achieved by providing a means for connecting a vertebral replacement implant to a longitudinal member extending along the length of the spine between adjacent complete vertebrae. This longitudinal member can be used to deflect the space created by the removed vertebra to facilitate insertion of a replacement implant. Yet another object is to provide an implant that can contain bone growth material to facilitate fusion of the height location where the device is mounted. One advantage of the vertebral body of the present invention is that it provides a solid implant that supports the load of the spine while waiting for the bone growth material to fuse between the complete vertebrae. Yet another advantage is that the implant can be easily adjusted to accommodate space at different heights of the vertebra. Other objects and advantages of the present invention can be understood by referring to the following description of the invention and the accompanying drawings and claims. DESCRIPTION OF THE DRAWINGS FIG. 1 is an exploded perspective view of a spinal osteosynthetic implant according to prior art US Pat. No. 5,108,395. FIG. 2 shows a portion of FIG. 1 with the addition of a device that allows placement of an implant between vertebrae while holding a clamp associated with the prior art device of US Pat. No. 5,108,395. is there. FIG. 3 is an exploded perspective view of a vertebral body replacement assembly according to one embodiment of the present invention. FIG. 4 is an end view of an end plate used in connection with the vertebral body replacement assembly shown in FIG. FIG. 5 is a side view of an end plate used with the vertebral body replacement assembly of FIG. FIG. 6 is an exploded perspective view showing one component of a clamp assembly used with the vertebral body replacement assembly shown in FIG. FIG. 7 is a side view of a vertebral body replacement assembly according to another embodiment of the present invention, particularly suitable for use with an elongated rod that spans a vertebral portion. FIG. 8 is an end view of the vertebral body replacement assembly shown in FIG. 7 with the assembly in place above a complete vertebra. FIG. 9 is a side view of the assembly shown in FIG. 7 when engaged with an elongated rod. FIG. 10 is a perspective view of an end plate used with the vertebral body replacement assembly shown in FIG. FIG. 11 is an end view of one particular end plate for use with the vertebral body replacement assembly shown in FIG. 3 in the thoracic spine. DESCRIPTION OF THE PREFERRED EMBODIMENTS For the purpose of facilitating the understanding of the principles of the present invention, the following description will be given of the embodiments shown in the drawings using specific terms. However, this is not intended to limit the scope of the invention in any way, and variations and further modifications of the illustrated apparatus, and further applications of the illustrated principles of the invention, are not intended to It will be understood by those of ordinary skill in the art that Referring first to FIG. 3, a vertebral body replacement assembly 20 according to one embodiment of the present invention is illustrated. The assembly 20 generally includes a threaded cylinder 21, a threaded end plate 22, and an end cap 23. Also provided is a set screw 24 as one embodiment of means for securing each of the end plates 22 to the corresponding end of the cylindrical body 21. In one specific embodiment, the set screw 24 is a breakable locking screw whose head will shear when the tightening torque limit is reached. Such a locking screw is disclosed in co-pending French patent application No. 94 10 377 filed on Aug. 29, 1994. The threaded cylinder 21 is formed by a cylindrical wall 25 defining a hollow cavity 26. The cavity is configured to receive an osteosynthetic material, which can be in the form of a self or similar material. The cylindrical wall 25 is provided with a plurality of holes 28 communicating with the cavity 26. These holes provide a passageway for bone or tissue to grow in and further enhance the stability of the implant. The cylindrical wall 25 is configured to engage the support assembly 55 and has a second plurality of threaded holes 29 formed substantially midway between the implants, as described in more detail below. I have. In one important feature of the cylinder 21, both ends of the cylindrical wall 25 are formed with external threads 32. In one specific embodiment, the screws 32 extend from each other end over most of the length of the threaded cylinder 21 and are configured to engage the threaded end plate 22. ing. Each of the end plates is provided with a flange 35, which is preferably shaped to cover substantially the load bearing area of the adjacent complete vertebral body end plate. The cylindrical body 37 is integrally formed with a flange 35 which extends in the direction of the threaded cylindrical body 21 when the end plate 22 is placed in the cut vertebral space. Each cylindrical body 37 of the end plate has a number of threaded holes 39 therein for receiving the set screw 24. The cylindrical body 37 and the flange 35 of the end plate 22 define a through hole 40. On the inner surface of the hole 40, there is provided a female screw 41 configured to engage with the male screw 32 of the cylindrical body 21. In a preferred embodiment, the screw 41 extends at least along the entire length of the cylinder 37, and preferably extends into the flange 35. Further details of the end plate 22 can be seen in FIGS. As shown in FIG. 5, the cylindrical body 37 is integrally formed with a flange 35 so as to define an angle 43 of lordosis. This angle corresponds to the vertebra V shown in FIG. Three Vertebral body replacement assembly 20 to replace damaged vertebrae such as, and to maintain the normal anterior curvature of the spine at its height. is there. An end face 36 of the flange 35 is provided with a conduit hole 45 extending through the flange. These holes 45 are intended to provide a passageway that conduits the space between adjacent vertebrae. The end face 36 can be provided with four spikes, such as the spike 91 shown in the embodiment of FIG. Alternatively, a spike 120 (FIG. 3) having a threaded stem 121 that engages a threaded hole 46 formed in the end face 36 may be provided. In each case, the spikes (91, 120) are configured to penetrate the endplates of adjacent vertebrae to help maintain the implant in place at the "site". The end face is further provided with a mounting slot 47 traversing the flange 35 and straddling the chord of the internal hole 40. A hole 48 extends through each of the mounting slots. The cylindrical body 37 of the end plate 22 is provided with a mounting notch 49 aligned with each hole 48 of the mounting slot 47. These slots 47, holes 48, and cutouts 49 are configured to support the end cap 23, as described herein. Referring again to FIG. 3, the end cap 23 includes a generally rectangular support bar 50 mounted across the chord of a flat circular plate 52 of the end cap. Each end of the support bar 50 has a protrusion 51 projecting outward. Each of the projections 51 is sized to be received in a corresponding hole 48, while the support bar 50 itself is configured to fit into the mounting slot 47 of the flange 35. Further, each of the projections 51 slides conveniently into a corresponding mounting notch 49 of the cylindrical body 37. In this way, in particular, the complete vertebra V where the replacement object assembly is adjacent Two , V Four When placed between the end caps 23, the end cap 23 is held in place. The end cap 23 provides additional support for the implant between adjacent complete vertebrae. This end cap may be omitted if it is desired for the bone to grow between adjacent vertebrae and through the replacement object. Alternatively, the plate 52 of each end cap 23 allows bone ingrowth between the endplates of the vertebra and the bone growth material disposed within the threaded cylinder 21. You can also drill holes to get. In a preferred embodiment, the endplates are solid and shown as providing maximum load bearing capacity for loads along the length of the vertebral column. In the illustrated embodiment, the screws 32 provided on the cylindrical replacement body are male threads, while the end plate screws 40 are female threads. Alternatively, the end plate cylinder 37 may have external threads and the cylindrical alternative may have internal threads in the cavity 26. In this latter case, the inner diameter of the cylinder is naturally slightly larger than the outer diameter of the end plate cylinder. In a preferred embodiment, the cylindrical wall forming implant 21 can be relatively thin when compared to prior art alternatives. In one particular embodiment, the thickness of this wall is 1 mm. Since the primary load supported by the implant is not a bending load but an axial compression force, a thinner cylinder is suitable and even more desirable. The implant 21 also preferably has a number of holes 28, 29 to promote tissue ingrowth and ducting, thereby increasing the stability of the structure after fusion. In one particular embodiment, the total area of the plurality of holes is at least 25% of the surface area of the cylinder 21. In use, the vertebra V shown in FIG. Three Remove damaged vertebrae such as. In one embodiment, the clamp 2 of the internal implant 1 shown in FIGS. 1 and 2 engages the complete vertebral body in the manner shown in FIG. Also, as shown in FIG. 2, the forceps 10 can be used to deflect the complete vertebra to allow the vertebral replacement assembly 20 to be implanted. In a preferred method, the optimal height of the vertebra is set, and the threaded cylinder 21 and the threaded end plate 22 are attached together to achieve the proper height. In particular, each of the end caps can be screwed onto the threaded cylinder 21 until the desired height is obtained. It is important that the bottom edge 44 of the flange 35 of each endplate be oriented in substantially the same direction between the two threaded endplates 22. This orientation is important because the replacement assembly 20 is located between the two complete vertebrae abutting the endplates of these vertebrae. In order to maintain the maximum load bearing function, the flange 35, in particular the end face 36, should be in the shape of a vertebral body against which the end plate abuts, and its dimensions should be such that the area of the complete vertebra end plate is as small as possible. It is set to occupy a wide area. It is preferable to provide three types of such shapes so as to be able to cope with the anatomical differences of the vertebral bodies at the waist, chest-hip and waist level. The configuration of the flange 35 shown in FIG. 4 is applicable to the thoracic-lumbar vertebra. A smaller and more circular configuration is also possible for the flange 35 'shown in FIG. 11 to be implanted at chest level. The flange 35 'is also shown as having a relief radius 38 to allow for increased clearance between the flange and the dural space containing the spinal cord. This relief radius 38 is preferably included in all three types of end plate flange shapes. In one particular embodiment, the external threads 32 of the threaded cylinder 21 are formed in opposite directions so that only the cylinder can be rotated to draw or separate the end plates together. Thus, when the cylinder is rotated in one direction, the threads 32 at each end engage the female threads 41 on each end cap 23 in the correct direction to pull the end caps together. Alternatively, the direction of the screws 32 may be equal at each end, such that each end cap needs to be individually screwed into the cylinder 21 in the opposite direction. The disadvantage of this arrangement is that it becomes more difficult to adjust the overall height of the assembly 20 while maintaining the proper orientation of each of the lower edges 44 of the end faces 36. One advantage is that the assembly does not loose its own screws "on site." Once the end plate and the threaded cylinder have been engaged in the proper orientation to allow for the correct height, the set screw 24 is threaded into the appropriate opening of the threaded opening 39 of the cylinder 37 of the end plate 22. , So that the set screw 24 extends so as to contact the threaded cylinder 21. A set screw 24 (which can be a breakable locking screw as described above) applies clamping pressure to the cylinder 21 to hold the cylinder in place. Thus, the set screw 24 provides a means of securing the components together and preventing the cylinder 21 from rotating with respect to any of the end plates 22. Preferably, two set screws are used on each end plate 23 to ensure that the associated ends of the threaded cylinder 21 are securely fixed. The hole 28 in the threaded cylinder has a smaller diameter than the set screw 24 to ensure that the set screw 24 is retained on the body 21. Once the cylinder and endplate have been secured in their proper height dimensions, the bone graft material can be inserted into the hole 40 in the endplate and into the cavity 26 of the cylinder 21. After the interior of these components has been completely filled with the bone graft material, the ends 32 are extended so that the projections 51 extend through the holes 48 and the support bars 50 extend through the mounting slots 47 in each end plate. Place in place. Next, the deflected vertebra V Two , V Four The alternative assembly 20 can be located between the two. Once the assembly is in place and each end face 36 of the end plate 22 is properly oriented on the vertebral end plate, the biasing forceps 19 are removed and the assembly 20 is removed Be clamped in place between the two vertebrae. To further ensure that the replacement assembly 20 does not move or slide into place between the full vertebrae, a support assembly 55 may be provided. In the preferred embodiment, the support assembly 55 is configured to engage a clamp 2 used with the prior art anterior implant system illustrated in FIGS. The support assembly 55 may also include other front plates, such as the Z-plate ATL sold by Daneck Medical, Inc., or a rod system, such as the sofa mower SNC CD Hoff system. It is also possible to use with. In particular, the support assembly has a stabilizing plate 57, which can be of the same form as the plate 6 shown in FIG. 1 and which has a cut in the bottom of the end of the plate. To The means for connecting the vertebral replacement object assembly 20 to the plate 57 includes a clamp assembly 59 that securely grips the plate 57 and supports a locking screw 69. The clamp assembly 59 has a pair of clamp halves 60, which are preferably C-shaped to hold and support the plate 57. Each of the clamp halves 60 has a hole (not shown) for receiving the threaded rod 63 of the adjustment plate 62. A nut 64 is screwed onto the rod 63 to pull the clamp halves 60 together around the stabilizing plate 57. Details of this adjustment plate 62 are more clearly shown in FIG. The adjustment plate has a threaded rod 63 extending from a face 65 of the plate 62. The plate 62 has a through hole 67 having a circular seating surface 68. The round head 70 of the locking screw 69 is received in the through hole 67. The locking screw 69 has a hexagonal recess 71 in its head for receiving a driver tool. The locking screw 69 has a threaded shaft portion 73 adapted to engage with one of the threaded holes 29 of the threaded cylindrical body 21. A guide hub 75 having a smaller diameter than the threaded shaft portion 73 is provided to facilitate guiding the locking screw 69 to a predetermined position. The locking screw 69 preferably has a smooth shaft 74 between the screw head 70 and the threaded shaft 73. In use, the clamp half 60 is temporarily attached to the stabilizing plate 57, which is not clamped. This stabilizing plate 57 can then be engaged with the clamp 2 at each of the secure vertebral bodies and secured in place by a corresponding nut such as the nut 7 shown in FIG. Thus, with the stabilizing plate 57 attached between the deflected vertebrae, the biasing forceps 19 can be removed and the entire load of the spine can be carried by the replacement assembly 20. Once the biasing forceps have been removed, the clamp half 60 is adjusted along the length of the plate 57 and the locking screw 69 is aligned with the appropriate one of the threaded holes 29 in the threaded cylinder 21. You can make it. The spherical contact between the head 70 of the locking screw 69 and the circular seat 68 of the adjustment plate 62 allows the locking screw to take any angle necessary to engage the threaded hole 29. to enable. When so aligned, the locking screw 69 can be easily screwed into one of the holes 62 until locked between the adjustment plate 62 and the threaded cylinder 21. At this point, the clamp half 60 can be completely clamped on the plate 57 by tightening the nut 64 onto the threaded rod 63. In another embodiment of the present invention, vertebral body replacement assembly 80 is configured to connect to an elongated deflection rod or compression rod. In this embodiment, the assembly 80 has both end plates 83 configured to be screwably engaged with the cylindrical body 21 (the cylindrical body 21 is in all respects, as shown in FIG. 3). Is substantially the same as the cylindrical body 21 described above). In this embodiment, the end plate 83 has a flange 85 and a cylindrical body 87 protruding from the end plate. The cylindrical body 87 has a screw hole 88 formed to receive the male screw 32 of the cylindrical body 21. As in the case of the conventional end plate, the end plate 83 has a plurality of conduit holes 89 formed in the flange 85. The end face 86 of the flange 85 has a number of spikes 91 protruding from the end face. These spikes are configured to penetrate the endplates of adjacent vertebral bodies to help keep the implant in place "on site." As shown in FIGS. 7 and 8, the end plate 83 has an arm 94 projecting from a flange 85, one component of the means for connecting the implant to a longitudinal member (such as a rod 105). doing. A rod hole 95 is formed at a position adjacent to the free end 94 a of the arm 94, and a set screw hole 96 traverses the rod hole 95 from the free end of the arm 94. A set screw 98 for clamping the rod extending therethrough is provided to engage within the set screw hole 96. The method of using the replacement assembly 80 in this embodiment is shown in FIGS. In particular, the end plate 83 engages the appropriate vertebra via a spike 91. These plates are also configured to define an angle 115 that can correspond to the appropriate spinal anatomy at a particular vertebral level. Via bone screws 108, a deflection plate 107 is attached to each of the complete vertebrae. The plate 107 has a collar 109 formed integrally with the plate, and the deflection rod 105 passes through the collar 109. The deflection rod extends so as to pass through each of the rod holes 95 of the arm 94 of the end plate 83. Set screws 98 secure these end plates in place with the rod extending through each of the holes. A properly shaped instrument capable of engaging each collar 109 of the deflection plate 107 mounted within each vertebra can deflect the adjacent vertebra. Set screws (not shown) can be provided to secure the rod 105 inside each collar 109. A method for fixing the end plate to the threaded cylinder will be described with reference to FIGS. 7, 9 and 10. In particular, fixing means (in the form of crimping grooves 100 around the diameter of the cylindrical body) is provided on the end plate 83, specifically on the cylindrical body 87 of the end plate. On both sides of the cylindrical body, crimp notches 101 are formed in the grooves 100. In short, the crimp notch is a gap on the outer periphery of the groove 100. The crimp notch provides a gap that can be closed by a suitable gripping tool that grips the entire circumference of crimp groove 100. When the crimping tool is tightened, these notches 101 close when the grooves move together in the direction of arrow 102. It can be seen that this form of crimping is an alternative to the set screw 24 (the screw disclosed with respect to the previous embodiment) that secures the end plate to the threaded cylinder. Although the invention has been illustrated in the drawings and has been described in detail in the above description, this is by way of example only and is not intended to limit the features of the invention, but to make all changes and modifications belonging to the invention. It should be understood that the examples are intended to include the subject of protection.

【手続補正書】特許法第184条の8第1項 【提出日】1997年1月20日 【補正内容】 請求の範囲 1.隣接する完全な椎骨の間にて1つ又はより多くの除去した椎骨により形成 されたスペース内に介在される椎骨代替用インプラントにして、 前記完全な椎骨の間のスペースの一部を跨ぐ寸法とされた、両端を有する代替 物体であって、前記両端の各々に形成された第一のねじを有する前記代替物体を 備え、該代替物体が、中空の内部を画成する円筒壁を更に有し、該円筒壁が貫通 する複数の穴を画成し、該穴が前記代替物体の前記中空の内部と連通し、前記代 替物体内への組織の内部成長を促進し、 前記代替物体が、ある外表面積を有し、前記複数の穴が、該外表面積の約25% 以上の有効面積を画成し、 前記スペース内に前記インプラントを介在させたとき、前記完全な椎骨のそれ ぞれの1つと接触する端面を有する一対の端板を備え、該端板の各々が該端面か ら一体に伸長する円筒状部分を有し、該円筒状部分が、前記代替物体上の第一の ねじと螺着可能に係合する形態とされた第二のねじを有し、前記端板の各々が、 前記端面に及び前記円筒状部分に開口する貫通穴を更に画成する、椎骨代替用イ ンプラント。 4.請求項1に記載の椎骨代替用インプラントにして、前記代替物体の前記中 空の内部が前記両端にて開口している、椎骨代替用インプラント。 5.請求項1に記載の椎骨代替用インプラントにして、前記代替物体が中空の 内部を画成する円筒壁を有し、前記両端にて開口している、椎骨代替用インプラ ント。 6.請求項5に記載の椎骨代替用インプラントにして、前記端板の各々が前記 端面に及び前記円筒状部分にて開口する貫通穴を画成する、椎骨代替用インプラ ント。 7.請求項6に記載の椎骨代替用インプラントにして、前記代替物体上の前記 第一のねじが雄ねじであり、前記対の端板の前記円筒状部分上の前記第二のねじ が雌ねじである、椎骨代替用インプラント。 8.請求項1に記載の椎骨代替用インプラントにして、その前記端面にて前記 端板の1つの前記穴を閉じる端部キャップを更に備え、該端部キャップが、該端 部キャップを前記端板の上に支持する手段を有する、椎骨代替用インプラント。 9.請求項1に記載の椎骨代替用インプラントにして、前記代替物体上の前記 第一のねじが雄ねじであり、前記対の端板の前記円筒状部分上の前記第二のねじ が雌ねじである、椎骨代替用インプラント。 10.請求項1に記載の椎骨代替用インプラントにして、前記代替物体を前記端 板の各々に対して固定し、前記第一及び第二のねじの緩みを防止する手段を更に 備える、椎骨代替用インプラント。 11.請求項10に記載の椎骨代替用インプラントにして、前記固定手段が、 前記対の端板の各々の前記円筒状部分に画成された多数の開口部と、 該多数の穴の1つを貫通して伸長し、前記代替物体と接触可能な部材とを備え る、椎骨代替用インプラント。 12.請求項11に記載の椎骨代替用インプラントにして、 前記部材が止めねじであり、 前記多数の開口部には、前記止めねじを螺着係合状態に受け入れ得るようにね じが形成される、椎骨代替用インプラント。 13.請求項11に記載の椎骨代替用インプラントにして、前記多数の開口部が 前記第二のねじにて前記端板に画成される、椎骨代替用インプラント。 14.請求項1に記載の椎骨代替用インプラントにして、前記端板の各々が前記 端面を画成するフランジを備え、該フランジが前記円筒状部分から半径方向外方 に伸長し、該フランジが、前記端板が接触している前記完全な椎骨の一部分の形 状に略対応する形状を画成する、椎骨代替用インプラント。 15.請求項14に記載の椎骨代替用インプラントにして、前記フランジが、貫 通する導管化穴を多数画成する、椎骨代替用インプラント。 16.隣接する完全な椎骨の間にて1つ又はより多くの除去した椎骨により形成 されたスペース内に介在される椎骨代替用インプラントにして、 完全な椎骨の間のスペースの一部を跨ぐ寸法とされた、両端を有する代替物体 であって、前記両端の各々に形成された第一のねじを有する前記代替物体と、 前記スペース内に前記インプラントを介在させたとき、前記完全な椎骨のそれ ぞれの1つと接触する端面を有する一対の端板とを備え、該端板の各々が該端面 から一体に伸長する円筒状部分を有し、該円筒状部分が、前記代替物体上の前記 第一のねじと螺着可能に係合する形態とされた第二のねじを有し、前記端板の各 々が、前記端面に及び前記円筒状部分に開口する貫通穴を更に画成し、その前記 端面にて前記端板の1つの前記穴を閉じる端部キャップを備え、該端部キャップ が、 前記端板に形成された前記穴開口部に対応する形状とされたプレートと、 前記端板に取り付けられた支持バーとを備え、 前記端板が、前記支持バーを受け入れ得るように前記端面に画成されたスロッ トを更に有し、前記端部キャップの前記プレートが前記端板の前記端面と平らに 位置するようにした、椎骨代替用インプラント。 17.隣接する完全な椎骨の間にて1つ又はより多くの除去した椎骨により形成 されたスペース内に介在される椎骨代替用インプラントにして、 完全な椎骨の間のスペースの一部を跨ぐ寸法とされた、両端を有する代替物体 であって、前記両端の各々に形成された第一のねじを有する前記代替物体と、 前記スペース内に前記インプラントを介在させたとき、各々が前記完全な椎骨 のそれぞれの1つと接触する端面を有する一対の端板とを備え、該端板の各々が 該端面から一体に伸長する円筒状部分を有し、該円筒状部分が、前記代替物体上 の前記第一のねじと螺着可能に係合する形態とされた第二のねじを有し、前記端 板の各々が、前記端面に及び前記円筒状部分に開口する貫通穴を更に画成し、前 記端板の各々の前記円筒状部分が前記端面から突き出す長さと、該長さの一部に 沿って形成された圧着切欠きとを更に有し、 前記円筒状部分が、該圧着切欠きにて変形し、該切欠きを閉じ、これにより、 前記代替物体が前記端板の円筒状部分に螺着可能に係合したとき、該代替物体の 周りの前記円筒状部分の外周が縮小するようにした、椎骨代替用インプラント。 18.請求項1に記載の椎骨代替用インプラントにして、前記対の端板の各々が 前記隣接する完全な椎骨の対応する1つに植え込むべく前記端面から突き出す多 数のスパイクを備える、椎骨代替用インプラント。 19.隣接する完全な椎骨の間にて1つ又はより多くの除去した椎骨により形成 されたスペース内に介在される椎骨代替用インプラントにして、 完全な椎骨の間のスペースの一部を跨ぐ寸法とされた、両端を有する代替物体 であって、前記両端の各々に形成された第一のねじを有する前記代替物体と、 前記スペース内に前記インプラントを介在させたとき、各々が前記完全な椎骨 夫々の1つと接触する端面を有する一対の端板とを備え、該端板の各々が該端面 から一体に伸長する円筒状部分を有し、該円筒状部分が、前記代替物体上の前記 第一のねじと螺着可能に係合する形態とされた第二のねじを有し、前記端板の各 々が、前記端面に及び前記円筒状部分に開口する貫通穴を更に画成し、前記対の 端板の各々の前記端面が多数のねじ付き穴を画成し、前記隣接する完全な椎骨の 対応する1つに植え込むべく前記端面から突き出す多数のスパイクを備え、 該スパイクの各々が、前記端板の各々の前記端面における前記ねじ付き穴と係 合し得る形態とされたねじ付きポストを備える、椎骨代替用インプラント。 20.隣接する完全な椎骨の間にて1つ又はより多くの除去した椎骨により形成 されたスペース内に介在される椎骨代替用インプラントにして、 完全な椎骨の間のスペースの一部を跨ぐ寸法とされた、両端を有する代替物体 であって、前記両端の各々に形成された第一のねじを有する前記代替物体と、 前記スペース内に前記インプラントを介在させたとき、各々が前記完全な椎骨 の夫々の1つと接触する端面を有する一対の端板を備え、該端板の各々が該端面 から一体に伸長する円筒状部分を有し、該円筒状部分が、前記代替物体上の前記 第一のねじと螺着可能に係合する形態とされた第二のねじを有し、前記端板の各 々が、前記端面に及び前記円筒状部分に開口する貫通穴を更に画成し、前記端板 の各々の前記円筒状部分が垂直でない角度にて前記端面から伸長し、該角度が、 前記除去した椎骨により形成されるスペースにおける脊柱の曲率に対応する、椎 骨代替用インプラント。 21.隣接する完全な椎骨の間にて1つ又はより多くの除去した椎骨により形成 されたスペース内に介在される椎骨代替用インプラントにして、 完全な椎骨の間のスペースの一部を跨ぐ寸法とされた、両端を有する代替物体 であって、前記両端の各々に形成された第一のねじを有する前記代替物体と、 前記スペース内に前記インプラントを介在させたとき、前記完全な椎骨のそれ ぞれの1つと接触する端面を有する一対の端板とを備え、該端板の各々が該端面 から一体に伸長する円筒状部分を有し、該円筒状部分が、前記代替物体上の前記 第一のねじと螺着可能に係合する形態とされた第二のねじを有し、前記端板の各 々が、前記端面に及び前記円筒状部分に開口する貫通穴を更に画成し、前記端板 の各々が、前記端面を画成し且つ前記円筒状部分から外方に伸長するフランジを 更に備え、 該フランジが、前記円筒状部分から突き出すアームを備え、 該アームが、前記脊柱の長さに沿って配置された長手方向部材に係合すべく前 記隣接する完全な椎骨を超えて伸長する形態とされた自由端を有する、椎骨代替 用インプラント。 22.請求項21に記載の椎骨代替用インプラントにして、前記アームが、前記 長手方向部材を受け入れるべく前記自由端に穴を画成する、椎骨代替用インプラ ント。 25.損傷した中間の椎骨を除去した後、隣接する完全な椎骨を固定する組立体 にして、 椎骨代替用インプラントを備え、該インプラントが、 該損傷した椎骨の除去により形成されるスペースの一部を跨ぐ寸法とされた 両端を有する代替物体であって、第一のねじが形成され且つその外周に沿って多 数のねじ付き穴が形成された前記代替物体と、 前記インプラントが前記スペース内に介在されたとき、前記完全な椎骨のそ れぞれの1つに接触する端面を有する一対の端板とを備え、 該端板の各々が、前記端面から一体に伸長する円筒状部分を有し、 該円筒状部分が、前記代替物体上の前記ねじと螺着可能に係合する形態とされ た第二のねじを有し、 前記損傷した椎骨を除去することにより形成されるスペースの外側にて前記隣 接する完全な椎骨を跨ぎ且つ該椎骨に固定状態に係合し得る寸法とされた細長い 長手方向部材と、 該椎骨代替用インプラントを前記長手方向部材に接続するクランプとを備え、 該クランプが、円形の着座部を有する穴を画成するプレートを備え、 前記ねじ付き開口部の1つに係合するねじを有して、前記クランプに取り付け られたねじであって、前記円形の着座部に係合する形態とされた丸形の頭部を有 する前記ねじを備える、組立体。 26.損傷した中間の椎骨を除去した後、隣接する完全な椎骨を固定する組立体 にして、 椎骨代替用インプラントを備え、該インプラントが、 該損傷した椎骨の除去により形成されるスペースの一部を跨ぐ寸法とされた 、両端を有する代替物体であって、第一のねじが形成された前記代替物体と、 前記インプラントが前記スペース内に介在されたとき、前記完全な椎骨のそ れぞれの1つに接触する端面を有する一対の端板であって、その各々が、前記端 面から一体に伸長する円筒状部分を有する前記一対の端板とを備え、該円筒状部 分が前記代替物体上の前記ねじと螺着可能に係合する形態とされた第二のねじを 有し、前記端板の各々が、前記端面を画成するフランジであって、前記円筒状部 分から外方に伸長する前記フランジを備え、 前記損傷した椎骨を除去することにより形成されるスペースの外側にて前記隣 接する完全な椎骨を跨ぎ且つ該椎骨に固定状態に係合し得る寸法とされた細長い 長手方向部材と、前記椎骨代替用インプラントを該長手方向部材に接続する接続 手段とを備え、 該接続手段が、前記フランジと一体で且つ前記円筒状部分から突き出すアーム を備え、該アームが、前記長手方向部材に係合し得るように、前記隣接する完全 な椎骨を超えて伸長する形態とされた自由端を有する、組立体。 27.隣接する完全な椎骨を固定する請求項26に記載の組立体にして、 前記アームが、前記長手方向部材を受け入れるべく前記自由端に形成された第 一の穴と、該第一の穴を横断するように前記自由端に形成された止めねじ穴とを 画成し、 前記接続手段が、前記止めねじ穴内にねじ込まれる止めねじを有し、 該止めねじが、前記第一の穴を貫通して伸長する長手方向部材に係合する先端 を有する、組立体。 28.隣接する完全な椎骨の間にて除去した椎骨により形成されるスペース内に 介在される椎骨代替用インプラントにして、 両端を有し且つ前記完全な椎骨間のスペースの一部を跨ぐ寸法とされた長さを 有する代替物体と、 前記インプラントが前記スペース内に介在されたとき、各々が前記完全な椎骨 のそれぞれの1つに接触する端面を有する一対の端板であって、その各々が、前 記端面から一体に伸長する係合部分を有する前記一対の端板と、 前記代替物体の前記長さに沿った可変位置にて前記端板を前記代替物体に係合 させるべく前記代替物体の前記両端と前記端板の各々の前記係合部分との間に設 けられたかみ合いねじと、 該かみ合いねじが非係合状態となるのを防止し得るように前記代替物体を前記 端板の各々に固定する手段とを備える、椎骨代替用インプラント。 31.2つの完全な椎骨の間にて除去した椎骨により形成されるスペース内に介 在される椎骨代替用インプラントにして、 中空の内部を画成する肉厚の薄い円筒体を備え、該円筒体の壁が、該円筒体の 外表面積の25%に少なくとも等しい合計面積を有する複数の穴を画成し、 該円筒体が前記両端の各々に形成された連続的なねじを有する両端を備え、 一対の端板を備え、該端板の各々が、インプラントが前記スペース内に介在さ れたとき、前記完全な椎骨のそれぞれの1つと接触する端面を画成するフランジ により形成され、 該端板の各々が、前記フランジから一体に突き出す円筒状部分を更に備え、 該円筒状部分が、前記肉厚の薄い円筒体の前記両端における前記ねじと係合す る連続的なねじを画成し、 前記端板の各々が、前記円筒体が前記端板と螺着可能に係合したとき、前記肉 厚の薄い円筒体の前記中空の内部と連通する貫通穴を画成し、 前記円筒状部分が前記端面から突き出す長さを有する該円筒状部分の前記長さ の一部に沿って形成された圧着切欠きを画成し、 該円筒状部分が前記圧着切欠きにて変形し、該切欠きを閉じ、これにより、前 記円筒体が前記端板の円筒状部分と螺着可能に係合したとき、前記円筒体の周り における前記円筒状部分の外周が小さくなるようにした、椎骨代替用インプラン ト。 33.請求項1に記載の椎骨代替用インプラントにして、前記複数の穴の一部が 前記代替物体の前記第一のねじを貫通して伸長する、椎骨代替用インプラント。 34.請求項7に記載の椎骨代替用インプラントにして、前記代替物体が中空の 内部を画成する円筒壁を有し、 該円筒壁が複数の貫通穴を画成し、 該穴が前記代替物体の前記中空の内部と連通し、前記代替物体内への組織の内 部成長を促進する、椎骨代替用インプラント。 35.請求項34に記載の椎骨代替用インプラントにして、前記複数の穴の一部 が前記代替物体の前記雄ねじを貫通して伸長する、椎骨代替用インプラント。 36.請求項28に記載の椎骨代替用インプラントにして、 前記対の端板の前記係合部分が少なくとも1つのねじ付き貫通穴を有し、 前記固定手段が、前記円筒体を前記端板と螺着係合させたとき、前記ねじ付き 開口部内にねじ込まれ且つ前記代替物体と接触するようにした止めねじを有する 、椎骨代替用インプラント。[Procedure of Amendment] Article 184-8, Paragraph 1 of the Patent Act [Submission date] January 20, 1997 [Correction contents]                              The scope of the claims   1. Formed by one or more removed vertebrae between adjacent complete vertebrae Vertebral replacement implant interposed in the space that was   Alternative with two ends sized to span part of the space between the complete vertebrae The alternative object, wherein the alternative object has a first screw formed at each of the ends. The alternative object further comprises a cylindrical wall defining a hollow interior, the cylindrical wall penetrating therethrough. A plurality of holes, the holes communicating with the hollow interior of the replacement object; Promotes tissue ingrowth into the replacement object,   The replacement object has an outer surface area, and the plurality of holes have about 25% of the outer surface area. The above effective area is defined,   When the implant is interposed in the space, that of the complete vertebra A pair of end plates each having an end surface in contact with one of the end plates, each of the end plates being A cylindrical portion extending integrally therewith, the cylindrical portion being a first portion on the replacement object. A second screw configured to threadably engage the screw, wherein each of the end plates is A vertebral replacement implant further defining a through hole opening in the end face and in the cylindrical portion. Plant.   4. 2. A vertebral replacement implant according to claim 1 wherein said intermediate portion of said replacement object A vertebral replacement implant having an empty interior open at the ends.   5. 2. A vertebral replacement implant according to claim 1, wherein the replacement object is hollow. A vertebral replacement implant having a cylindrical wall defining an interior and open at both ends; And   6. 6. The vertebral replacement implant of claim 5, wherein each of the endplates is A vertebral replacement implant defining a through hole opening in the end face and at the cylindrical portion And   7. 7. A vertebral replacement implant according to claim 6, wherein the implant is on the replacement object. A first screw is a male screw and the second screw on the cylindrical portion of the pair of end plates A vertebral replacement implant, wherein is a female screw.   8. A vertebral replacement implant according to claim 1 wherein said end surface is An end cap for closing one of the holes in the end plate; A vertebral replacement implant having means for supporting a head cap over the endplate.   9. 2. A vertebral replacement implant according to claim 1, wherein said implant is on said replacement object. A first screw is a male screw and the second screw on the cylindrical portion of the pair of end plates A vertebral replacement implant, wherein is a female screw. 10. 2. A vertebral replacement implant according to claim 1, wherein the replacement object is the end piece. Means for securing to each of the plates to prevent loosening of said first and second screws. A vertebral replacement implant. 11. A vertebral replacement implant according to claim 10, wherein the fixation means comprises:   A number of openings defined in the cylindrical portion of each of the pair of end plates;   A member extending through one of the plurality of holes and capable of contacting the replacement object. Vertebral replacement implant. 12. A vertebral replacement implant according to claim 11,   The member is a set screw,   The multiple openings are adapted to receive the set screw in a threaded engagement. A vertebral replacement implant, where the spine is formed. 13. 12. The vertebral replacement implant of claim 11, wherein the plurality of openings are A vertebral replacement implant defined in the endplate with the second screw. 14. 2. The vertebral replacement implant of claim 1, wherein each of the endplates is A flange defining an end face, wherein the flange is radially outward from the cylindrical portion. And the flange is shaped to form a portion of the complete vertebra with which the end plate is in contact. A vertebral replacement implant that defines a shape substantially corresponding to the shape. 15. 15. The vertebral replacement implant of claim 14, wherein the flange has a through hole. A vertebral replacement implant that defines a number of conduit holes through which it passes. 16. Formed by one or more removed vertebrae between adjacent complete vertebrae Vertebral replacement implant interposed in the space that was   Alternative object with both ends sized to span part of the space between complete vertebrae Said replacement object having a first screw formed on each of said ends;   When the implant is interposed in the space, that of the complete vertebra A pair of end plates each having an end surface in contact with one of the end plates, each of the end plates being A cylindrical portion extending integrally therefrom, wherein said cylindrical portion is provided on said replacement object. A second screw configured to threadably engage the first screw, wherein each of the end plates Each further define a through hole opening in said end face and in said cylindrical portion, An end cap that closes one of the holes in the end plate at an end face; But,     A plate shaped to correspond to the hole opening formed in the end plate,     A support bar attached to the end plate,   The end plate has a slot defined in the end surface for receiving the support bar. And the plate of the end cap is flush with the end face of the end plate. A vertebral replacement implant positioned. 17. Formed by one or more removed vertebrae between adjacent complete vertebrae Vertebral replacement implant interposed in the space that was   Alternative object with both ends sized to span part of the space between complete vertebrae Said replacement object having a first screw formed on each of said ends;   When the implant is interposed in the space, each complete vertebra A pair of end plates having an end surface in contact with each one of the end plates, each of the end plates being A cylindrical portion extending integrally from the end surface, wherein the cylindrical portion is disposed on the substitute object. A second screw configured to threadably engage with the first screw of Each of the plates further defines a through hole opening in said end face and in said cylindrical portion; The length of each cylindrical portion of the end plate protruding from the end face, and a part of the length And a crimp notch formed along the   The cylindrical portion is deformed at the crimp notch and closes the notch, When the replacement object is threadably engaged with the cylindrical portion of the end plate, A vertebral replacement implant, wherein the outer circumference of the surrounding cylindrical portion is reduced. 18. The vertebral replacement implant of claim 1, wherein each of the pair of end plates is Multiple protruding from the end surface to be implanted in a corresponding one of the adjacent complete vertebrae A vertebral replacement implant with a number of spikes. 19. Formed by one or more removed vertebrae between adjacent complete vertebrae Vertebral replacement implant interposed in the space that was   Alternative object with both ends sized to span part of the space between complete vertebrae Said replacement object having a first screw formed on each of said ends;   When the implant is interposed in the space, each complete vertebra A pair of end plates having end surfaces in contact with respective ones of said end plates, each of said end plates being A cylindrical portion extending integrally therefrom, wherein said cylindrical portion is provided on said replacement object. A second screw configured to threadably engage the first screw, wherein each of the end plates Each further define a through hole opening in the end face and in the cylindrical portion, the pair of The end face of each of the end plates defines a number of threaded holes, and the adjacent complete vertebrae Comprising a number of spikes protruding from said end face for implantation in a corresponding one;   Each of the spikes is associated with the threaded hole in the end face of each of the end plates. A vertebral replacement implant comprising a threaded post configured to fit. 20. Formed by one or more removed vertebrae between adjacent complete vertebrae Vertebral replacement implant interposed in the space that was   Alternative object with both ends sized to span part of the space between complete vertebrae Said replacement object having a first screw formed on each of said ends;   When the implant is interposed in the space, each complete vertebra A pair of end plates having an end surface in contact with each one of the end surfaces, each of the end plates being A cylindrical portion extending integrally therefrom, wherein said cylindrical portion is provided on said replacement object. A second screw configured to threadably engage the first screw, wherein each of the end plates Each further defining a through hole opening in said end face and in said cylindrical portion; Each of the cylindrical portions extends from the end surface at a non-perpendicular angle, the angle comprising: A vertebrae corresponding to the curvature of the spine in the space formed by the removed vertebrae; Bone replacement implant. 21. Formed by one or more removed vertebrae between adjacent complete vertebrae Vertebral replacement implant interposed in the space that was   Alternative object with both ends sized to span part of the space between complete vertebrae Said replacement object having a first screw formed on each of said ends;   When the implant is interposed in the space, that of the complete vertebra A pair of end plates each having an end surface in contact with one of the end plates, each of the end plates being A cylindrical portion extending integrally therefrom, wherein said cylindrical portion is provided on said replacement object. A second screw configured to threadably engage the first screw, wherein each of the end plates Each further defining a through hole opening in said end face and in said cylindrical portion; Each define a flange defining the end face and extending outwardly from the cylindrical portion. In addition,   The flange includes an arm projecting from the cylindrical portion;   The arm is adapted to engage a longitudinal member disposed along the length of the spine. Vertebral replacement having a free end configured to extend beyond the adjacent complete vertebra For implants. 22. 22. The vertebral replacement implant of claim 21, wherein the arm comprises the arm. A vertebral replacement implant defining a hole in the free end to receive a longitudinal member And 25. Assembly for removing adjacent intermediate vertebrae after removing damaged intermediate vertebrae And then   A vertebral replacement implant, wherein the implant comprises:     Dimensioned to span a portion of the space created by removal of the damaged vertebra An alternative object having both ends, wherein a first screw is formed and multiple along the outer periphery thereof. Said alternative body in which a number of threaded holes are formed;     When the implant is interposed in the space, the complete vertebrae A pair of end plates having end surfaces that contact each one,   Each of the end plates has a cylindrical portion extending integrally from the end surface,   The cylindrical portion is configured to threadably engage the screw on the replacement object. Having a second screw,   Outside the space created by removing the damaged vertebrae, Elongate sized to span and completely engage abutting complete vertebra A longitudinal member;   A clamp connecting the vertebral replacement implant to the longitudinal member.   The clamp includes a plate defining a hole having a circular seat;   Attached to the clamp with a screw engaging one of the threaded openings Screw having a round head configured to engage the circular seat. An assembly comprising the screw. 26. Assembly for removing adjacent intermediate vertebrae after removing damaged intermediate vertebrae And then   A vertebral replacement implant, wherein the implant comprises:     Dimensioned to span a portion of the space created by removal of the damaged vertebra An alternative object having both ends, wherein said alternative object is formed with a first screw;     When the implant is interposed in the space, the complete vertebrae A pair of end plates each having an end surface contacting one of said end plates, each of said end plates being The pair of end plates having a cylindrical portion extending integrally from a surface thereof. A second screw configured to threadably engage the screw on the replacement object. Wherein each of said end plates is a flange defining said end surface, said cylindrical portion Comprising the flange extending outwardly from the minute,   Outside the space created by removing the damaged vertebrae, Elongate sized to span and completely engage abutting complete vertebra A longitudinal member and a connection connecting the vertebral replacement implant to the longitudinal member And means,   An arm integral with the flange and projecting from the cylindrical portion Wherein the arm is adapted to engage the longitudinal member so that the adjacent full An assembly having a free end configured to extend beyond a natural vertebra. 27. 27. The assembly of claim 26 for securing adjacent complete vertebrae,   A second arm formed at the free end to receive the longitudinal member; One hole and a set screw hole formed at the free end so as to traverse the first hole. Define   The connection means has a set screw screwed into the set screw hole,   A tip wherein the set screw engages a longitudinal member extending through the first hole An assembly having: 28. In the space formed by the removed vertebrae between adjacent complete vertebrae To make an implant for vertebral replacement   A length that has both ends and is dimensioned to span a portion of the space between the complete vertebrae An alternative object having   When the implant is interposed in the space, each complete vertebra A pair of end plates each having an end surface contacting a respective one of the end plates; The pair of end plates having an engaging portion extending integrally from the end surface,   Engage the end plate with the replacement object at a variable position along the length of the replacement object Between the opposite ends of the replacement object and the engagement portions of each of the end plates. With a screw   The alternative object is replaced with the mating screw to prevent the engagement screw from being disengaged. Means for securing to each of the end plates. 31. Intervening in the space formed by the removed vertebra between two complete vertebrae Vertebral replacement implants   A thin-walled cylinder defining a hollow interior, wherein the wall of the cylinder is Defining a plurality of holes having a total area at least equal to 25% of the outer surface area;   The cylindrical body has opposite ends having continuous threads formed at each of the opposite ends;   A pair of end plates, each of which has an implant interposed within said space. A flange that defines an end surface that contacts the respective one of the full vertebrae when retracted Formed by   Each of the end plates further comprises a cylindrical portion projecting integrally from the flange;   The cylindrical portion engages the threads at the ends of the thin walled cylinder. To define a continuous screw   When each of the end plates is threadably engaged with the end plate, the meat Defining a through hole communicating with the hollow interior of the thin cylinder,   The length of the cylindrical portion having a length that the cylindrical portion protrudes from the end face; Defining a crimp notch formed along part of the   The cylindrical portion deforms at the crimp notch and closes the notch, thereby When the cylindrical body is threadably engaged with the cylindrical portion of the end plate, around the cylindrical body Vertebral replacement implant wherein the outer circumference of the cylindrical portion is reduced G. 33. 2. The vertebral replacement implant of claim 1, wherein a portion of the plurality of holes is A vertebral replacement implant extending through the first screw of the replacement object. 34. A vertebral replacement implant according to claim 7, wherein the replacement object is hollow. Having a cylindrical wall defining the interior,   The cylindrical wall defines a plurality of through holes;   The hole communicates with the hollow interior of the replacement object to allow tissue into the replacement object. A vertebral replacement implant that promotes head growth. 35. 35. The vertebral replacement implant of claim 34, wherein a portion of the plurality of holes is provided. A vertebral replacement implant extending through the external thread of the replacement object. 36. A vertebral replacement implant according to claim 28,   The engagement portion of the pair of end plates has at least one threaded through hole;   When the fixing means engages the cylindrical body with the end plate by screwing, Having a set screw screwed into the opening and in contact with the replacement object , Vertebral replacement implant.

───────────────────────────────────────────────────── フロントページの続き (72)発明者 シュヴァリエ,ジャン−ルイ フランス共和国エフ−62155,メルリモン −プラージュ,アヴニュ・ダルトワ 57 (72)発明者 モルオー,ジャン−シャルル フランス共和国エフ−62520,ル・トゥケ −パリ−プラージュ,アヴニュ・デ・カナ ディヤン,ヴィルラ・ラ・ミュザルデ────────────────────────────────────────────────── ─── Continuation of front page    (72) Inventor Chevalier, Jean-Louis             F-62155, Merlimont, France             —Plage, Avignon D'artois 57 (72) Morau, Jean-Charles             France F-62520, Le Touquet             —Paris-Plage, Avne des Cana             Dijan, Virula la Musarde

Claims (1)

【特許請求の範囲】 1.隣接する完全な椎骨の間にて1つ又はより多くの除去した椎骨により形成 されたスペース内に介在される椎骨代替用インプラントにして、 完全な椎骨の間のスペースの一部を跨ぐ寸法とされた、両端を有する代替物体 であって、該両端の各々に形成された第一のねじを有する前記代替物体と、 前記スペース内に前記インプラントを介在させたとき、前記完全な椎骨のそれ ぞれの1つと接触する端面を有する一対の端板を備え、該端板の各々が該端面か ら一体に伸長する円筒状部分を有し、該円筒状部分が、前記代替物体上の第一の ねじと螺着可能に係合する形態とされた第二のねじを有し、前記端板の各々が、 前記端面に及び前記円筒状部分に開口する貫通穴を更に画成する、椎骨代替用イ ンプラント。 2.請求項1に記載の椎骨代替用インプラントにして、前記代替物体が中空の 内部を画成する円筒壁を有し、該円筒壁が貫通する複数の穴を画成し、該穴が、 前記代替物体の前記中空の内部と連通し、前記代替物体内への組織の内部成長を 促進する、椎骨代替用インプラント。 3.請求項2に記載の椎骨代替物体にして、前記代替物体を画成する前記円筒 壁が、ある表面積を有し、該複数の穴が、該表面積の25%以上の有効面積を画成 する、椎骨代替物体。 4.請求項2に記載の椎骨代替用インプラントにして、前記代替物体の前記中 空の内部が前記両端にて開口している、椎骨代替用インプラント。 5.請求項1に記載の椎骨代替用インプラントにして、前記代替物体が中空の 内部を画成する円筒壁を有し、前記両端にて開口している、椎骨代替用インプラ ント。 6.請求項5に記載の椎骨代替用インプラントにして、前記端板の各々が前記 端面に及び前記円筒状部分にて開口する貫通穴を画成する、椎骨代替用インプラ ント。 7.請求項6に記載の椎骨代替用インプラントにして、前記代替物体上の前記 第一のねじが雄ねじであり、前記対の端板の前記円筒状部分上の前記第二のねじ が雌ねじである、椎骨代替用インプラント。 8.請求項1に記載の椎骨代替用インプラントにして、その前記端面にて前記 端板の1つの前記穴を閉じる端部キャップを更に備え、該端部キャップが、該端 部キャップを前記端板の上に支持する手段を有する、椎骨代替用インプラント。 9.請求項1に記載の椎骨代替用インプラントにして、前記代替物体上の前記 第一のねじが雄ねじであり、前記対の端板の前記円筒状部分上の前記第二のねじ が雌ねじである、椎骨代替用インプラント。 10.請求項1に記載の椎骨代替用インプラントにして、前記代替物体を前記端 板の各々に対して固定し、前記第一及び第二のねじの緩みを防止する手段を更に 備える、椎骨代替用インプラント。 11.請求項10に記載の椎骨代替用インプラントにして、前記固定手段が、 前記対の端板の各々の前記円筒状部分に画成された多数の開口部と、 該多数の穴の1つを貫通して伸長し、前記代替物体と接触可能な部材とを備え る、椎骨代替用インプラント。 12.請求項11に記載の椎骨代替用インプラントにして、 前記部材が止めねじであり、 前記多数の開口部には、前記止めねじを螺着係合状態に受け入れ得るようにね じが形成される、椎骨代替用インプラント。 13.請求項11に記載の椎骨代替用インプラントにして、前記多数の開口部が 前記第二のねじにて前記端板に画成される、椎骨代替用インプラント。 14.請求項1に記載の椎骨代替用インプラントにして、前記端板の各々が前記 端面を画成するフランジを備え、該フランジが前記円筒状部分から半径方向外方 に伸長し、該フランジが、前記端板が接触している前記完全な椎骨の一部分の形 状に略対応する形状を画成する、椎骨代替用インプラント。 15.請求項14に記載の椎骨代替用インプラントにして、前記フランジが、貫 通する導管化穴を多数画成する、椎骨代替用インプラント。 16.請求項15に記載の椎骨代替用インプラントにして、 前記端部キャップが、 前記端板に形成された前記穴開口部に対応する形状とされたプレートと、 前記端板と、 該端板に取り付けられた支持バーとを備え、 前記端板が、前記支持バーを受け入れ得るように前記端面に画成されたスロッ トを有し、前記端部キャップの前記プレートが前記端板の前記端面と平らに位置 するようにした、椎骨代替用インプラント。 17.請求項10に記載の椎骨代替用インプラントにして、 前記端板の各々の前記円筒状部分が前記端面から突き出す長さを有し、 前記固定手段が、前記円筒状部分の前記長さの一部に沿って形成された圧着切 欠きを備え、 前記円筒状部分が、前記圧着切欠きにて変形し、前記切欠きを閉じ、これによ り、前記代替物体が前記端板の円筒状部分に螺着可能に係合したとき、該代替物 体の周りの前記円筒状部分の外周が縮小するようにした、椎骨代替用インプラン ト。 18.請求項1に記載の椎骨代替用インプラントにして、前記対の端板の各々が 前記隣接する完全な椎骨の対応する1つに植え込むべく前記端面から突き出す多 数のスパイクを備える、椎骨代替用インプラント。 19.請求項18に記載の椎骨代替用インプラントにして、 前記対の端板の各々の前記端面が多数のねじ付き穴を画成し、 前記多数のスパイクの各々が、前記端板の各々の前記端面における前記ねじ付 き穴と係合し得る形態とされたねじ付きポストを備える、椎骨代替用インプラン ト。 20.請求項1に記載の椎骨代替用インプラントにして、前記端板の各々の前記 円筒状部分が垂直でない角度にて前記端面から伸長し、該角度が、前記除去した 椎骨により形成されるスペースにおける脊柱の曲率に対応する、椎骨代替用イン プラント。 21.請求項1に記載の椎骨代替用インプラントにして、前記端板の各々が、前 記端面を画成し且つ前記円筒状部分から外方に伸長するフランジを備え、 該フランジが、前記円筒状部分から突き出すアームを備え、 該アームが、前記脊柱の長さに沿って配置された長手方向部材に係合すべく前 記隣接する完全な椎骨を超えて伸長する形態とされた自由端を有する、椎骨代替 用インプラント。 22.請求項21に記載の椎骨代替用インプラントにして、前記アームが、前記 長手方向部材を受け入れるべく前記自由端に穴を画成する、椎骨代替用インプラ ント。 23.損傷した中間の椎骨を除去した後、隣接する完全な椎骨を固定する組立体 にして、 椎骨代替用インプラントを備え、該インプラントが、 該損傷した椎骨の除去により形成されるスペースの一部を跨ぐ寸法とされた、 両端を有する代替物体であって、第一のねじが形成された前記代替物体と、 前記インプラントが前記スペース内に介在されたとき、前記完全な椎骨のそれ ぞれの1つに接触する端面を有する一対の端板とを備え、 該端板の各々が、前記端面から一体に伸長する円筒状部分を有し、 該円筒状部分が、前記代替物体上のねじと螺着可能に係合する形態とされた第 二のねじを有し、 前記損傷した椎骨を除去することにより形成されるスペースの外側にて前記隣 接する完全な椎骨を跨ぎ且つ該椎骨に固定状態に係合し得る寸法とされた細長い 長手方向部材と、 前記椎骨代替用インプラントを前記長手方向部材に接続する手段とを備える、 組立体。 24.隣接する完全な椎骨を固定する請求項23に記載の組立体にして、 前記代替物体が多数のねじ付き開口部を画成し、 前記接続手段が、 前記長手方向部材をクランプ止めするクランプと、 該クランプに取り付けられたねじであって、前記多数のねじ付き開口部の1 つに係合するねじと、前記クランプを前記長手方向部材に係合させたとき、前記 ねじが前記代替物体に係合するのに十分な長さを有する前記ねじとを備える、組 立体。 25.隣接する完全な椎骨を固定する請求項24に記載の組立体にして、 前記クランプが、円形の着座部を有する穴を画成するプレートを備え、 前記ねじが、前記円形の着座部に係合する形態とされた丸形の頭部を備える、 組立体。 26.隣接する完全な椎骨を固定する請求項22に記載の組立体にして、 前記端板の各々が、前記端面を画成するフランジであって、前記円筒状部分か ら外方に伸長する前記フランジを備え、 前記接続手段が、前記フランジと一体で且つ前記円筒状部分から突き出すアー ムを備え、該アームが、前記長手方向部材に係合し得るように、前記隣接する完 全な椎骨を超えて伸長する形態とされた自由端を有する、組立体。 27.隣接する完全な椎骨を固定する請求項26に記載の組立体にして、 前記アームが、前記長手方向部材を受け入れるべく前記自由端に形成された第 一の穴と、該第一の穴を横断するように前記自由端に形成された止めねじ穴とを 画成し、 前記接続手段が、前記止めねじ穴内にねじ込まれる止めねじを有し、 該止めねじが、前記第一の穴を貫通して伸長する長手方向部材に係合する先端 を有する、組立体。 28.隣接する完全な椎骨の間にて除去した椎骨により形成されるスペース内に 介在される椎骨代替用インプラントにして、 両端を有し且つ前記完全な椎骨間のスペースの一部を跨ぐ寸法とされた長さを 有する代替物体と、 前記インプラントが前記スペース内に介在されたとき、前記完全な椎骨のそれ ぞれの1つに接触する端面を有する一対の端板であって、その各々が、前記端面 から一体に伸長する係合部分を有する前記一対の端板と、 前記代替物体の前記長さに沿った可変位置にて前記端板を前記代替物体に係合 させるべく前記代替物体の前記両端と前記端板の各々の前記係合部分との間に設 けられた手段とを備える、椎骨代替用インプラント。 29.請求項28に記載の椎骨代替用インプラントにして、前記係合手段が、前 記代替物体の前記両端上に及び前記端板係合部分の各々に形成されたかみ合いね じを含む、椎骨代替用インプラント。 30.請求項28に記載の椎骨代替用インプラントにして、前記代替物体を前記 端板の各々に固定して、前記係合手段が非係合状態となるのを防止する手段を更 に備える、椎骨代替用インプラント。 31.2つの完全な椎骨の間にて除去した椎骨により形成されるスペース内に介 在される椎骨代替用インプラントにして、 中空の内部を画成する肉厚の薄い円筒体を備え、該円筒体の壁が、該円筒体の 外表面積の25%に少なくとも等しい合計面積を有する複数の穴を画成し、 該円筒体が前記両端の各々に形成された連続的なねじを有する両端を備え、 一対の端板を備え、該端板の各々が、インプラントが前記スペース内に介在さ れたとき、前記完全な椎骨のそれぞれの1つと接触する端面を画成するフランジ により形成され、 該端板の各々が、前記フランジから一体に突き出す円筒状部分を更に備え、 該円筒状部分が、前記肉厚の薄い円筒体の両端における前記ねじと係合する連 続的なねじを画成し、 前記端板の各々が、前記円筒体が前記端板と螺着可能に係合したとき、前記肉 厚の薄い円筒体の前記中空の内部と連通する貫通穴を画成する、椎骨代替用イン プラント。 32.請求項31に記載の椎骨代替用インプラントにして、 前記端板の各々の前記円筒状部分が前記端面から突き出す長さを有し、 前記円筒状部分が、該円筒状部分の前記長さの一部に沿って形成された圧着切 欠きを画成し、 該円筒状部分が前記圧着切欠きにて変形し、前記切欠きを閉じ、これにより、 前記円筒体が前記端板の円筒状部分と螺着可能に係合したとき、前記円筒体の周 りにおける前記円筒状部分の外周が小さくなるようにした、椎骨代替用インプラ ント。 33.請求項2に記載の椎骨代替用インプラントにして、前記複数の穴の一部が 前記代替物体の前記第一のねじを貫通して伸長する、椎骨代替用インプラント。 34.請求項7に記載の椎骨代替用インプラントにして、前記代替物体が中空の 内部を画成する円筒状壁を有し、 該円筒状壁が複数の貫通穴を画成し、 該穴が前記代替物体の前記中空の内部と連通し、前記代替物体内への組織の内 部成長を促進する、椎骨代替用インプラント。 35.請求項34に記載の椎骨代替用インプラントにして、前記複数の穴の一部 が前記代替物体の前記雄ねじを貫通して伸長する、椎骨代替用インプラント。[Claims]   1. Formed by one or more removed vertebrae between adjacent complete vertebrae Vertebral replacement implant interposed in the space that was   Alternative object with both ends sized to span part of the space between complete vertebrae Said replacement object having a first screw formed on each of said ends;   When the implant is interposed in the space, that of the complete vertebra A pair of end plates each having an end surface in contact with one of the end plates, each of the end plates being A cylindrical portion extending integrally therewith, the cylindrical portion being a first portion on the replacement object. A second screw configured to threadably engage the screw, wherein each of the end plates is A vertebral replacement implant further defining a through hole opening in the end face and in the cylindrical portion. Plant.   2. 2. A vertebral replacement implant according to claim 1, wherein the replacement object is hollow. A cylindrical wall defining an interior, the cylindrical wall defining a plurality of holes therethrough, the holes comprising: Communicates with the hollow interior of the replacement object to facilitate tissue ingrowth into the replacement object. Promotes vertebral replacement implants.   3. 3. The cylinder defining a vertebral replacement object according to claim 2 and defining the replacement object. The wall has a surface area, and the plurality of holes define an effective area of at least 25% of the surface area. Vertebral replacement object.   4. 3. A vertebral replacement implant according to claim 2, wherein the intermediate portion of the replacement object is provided. A vertebral replacement implant having an empty interior open at the ends.   5. 2. A vertebral replacement implant according to claim 1, wherein the replacement object is hollow. A vertebral replacement implant having a cylindrical wall defining an interior and open at both ends; And   6. 6. The vertebral replacement implant of claim 5, wherein each of the endplates is A vertebral replacement implant defining a through hole opening in the end face and at the cylindrical portion And   7. 7. A vertebral replacement implant according to claim 6, wherein the implant is on the replacement object. A first screw is a male screw and the second screw on the cylindrical portion of the pair of end plates A vertebral replacement implant, wherein is a female screw.   8. A vertebral replacement implant according to claim 1 wherein said end surface is An end cap for closing one of the holes in the end plate; A vertebral replacement implant having means for supporting a head cap over the endplate.   9. 2. A vertebral replacement implant according to claim 1, wherein said implant is on said replacement object. A first screw is a male screw and the second screw on the cylindrical portion of the pair of end plates A vertebral replacement implant, wherein is a female screw. 10. 2. A vertebral replacement implant according to claim 1, wherein the replacement object is the end piece. Means for securing to each of the plates to prevent loosening of said first and second screws. A vertebral replacement implant. 11. A vertebral replacement implant according to claim 10, wherein the fixation means comprises:   A number of openings defined in the cylindrical portion of each of the pair of end plates;   A member extending through one of the plurality of holes and capable of contacting the replacement object. Vertebral replacement implant. 12. A vertebral replacement implant according to claim 11,   The member is a set screw,   The multiple openings are adapted to receive the set screw in a threaded engagement. A vertebral replacement implant, where the spine is formed. 13. 12. The vertebral replacement implant of claim 11, wherein the plurality of openings are A vertebral replacement implant defined in the endplate with the second screw. 14. 2. The vertebral replacement implant of claim 1, wherein each of the endplates is A flange defining an end face, wherein the flange is radially outward from the cylindrical portion. And the flange is shaped to form a portion of the complete vertebra with which the end plate is in contact. A vertebral replacement implant that defines a shape substantially corresponding to the shape. 15. 15. The vertebral replacement implant of claim 14, wherein the flange has a through hole. A vertebral replacement implant that defines a number of conduit holes through which it passes. 16. A vertebral replacement implant according to claim 15,   The end cap is     A plate shaped to correspond to the hole opening formed in the end plate,     Said end plate;     A support bar attached to the end plate,   The end plate has a slot defined in the end surface for receiving the support bar. And the plate of the end cap is flush with the end face of the end plate. A vertebral replacement implant. 17. A vertebral replacement implant according to claim 10,   The cylindrical portion of each of the end plates has a length protruding from the end face;   The fixing means includes a crimp cut formed along a part of the length of the cylindrical portion. With a chip,   The cylindrical portion is deformed by the crimp notch and closes the notch. When the alternative object is threadably engaged with the cylindrical portion of the end plate, the alternative A vertebral replacement implant, wherein the outer circumference of the cylindrical portion around the body is reduced G. 18. The vertebral replacement implant of claim 1, wherein each of the pair of end plates is Multiple protruding from the end surface to be implanted in a corresponding one of the adjacent complete vertebrae A vertebral replacement implant with a number of spikes. 19. A vertebral replacement implant according to claim 18,   Said end face of each of said pair of end plates defines a number of threaded holes;   Each of the plurality of spikes is threaded on the end face of each of the end plates. A vertebral replacement implant having a threaded post configured to engage a puncture G. 20. 2. A vertebral replacement implant according to claim 1, wherein each of said endplates comprises A cylindrical portion extends from the end face at a non-perpendicular angle, the angle being removed. Vertebral replacement implant corresponding to the curvature of the spine in the space formed by the vertebrae plant. 21. 2. The vertebral replacement implant of claim 1, wherein each of the end plates is anterior. A flange defining the end face and extending outwardly from the cylindrical portion;   The flange includes an arm projecting from the cylindrical portion;   The arm is adapted to engage a longitudinal member disposed along the length of the spine. Vertebral replacement having a free end configured to extend beyond the adjacent complete vertebra For implants. 22. 22. The vertebral replacement implant of claim 21, wherein the arm comprises the arm. A vertebral replacement implant defining a hole in the free end to receive a longitudinal member And 23. Assembly for removing adjacent intermediate vertebrae after removing damaged intermediate vertebrae And then   A vertebral replacement implant, wherein the implant comprises:   Sized to span a portion of the space formed by removal of the damaged vertebra; An alternative object having both ends, wherein the alternative object is formed with a first screw;   That of the complete vertebra when the implant is interposed in the space A pair of end plates having end surfaces that contact each one,   Each of the end plates has a cylindrical portion extending integrally from the end surface,   A cylindrical portion configured to threadably engage a screw on the replacement object; With two screws,   Outside the space created by removing the damaged vertebrae, Elongate sized to span and completely engage abutting complete vertebra A longitudinal member;   Means for connecting the vertebral replacement implant to the longitudinal member. Assembly. 24. 24. The assembly of claim 23, which secures adjacent complete vertebrae,   Said replacement object defining a number of threaded openings;   The connection means,     A clamp for clamping the longitudinal member;     A screw attached to the clamp, wherein the one of the plurality of threaded openings is And the clamp engages the longitudinal member when the clamp is engaged with the longitudinal member. Said screw having a length sufficient to engage said replacement object. Three-dimensional. 25. 25. The assembly of claim 24 for securing an adjacent complete vertebra.   The clamp comprises a plate defining a hole having a circular seat;   Wherein the screw comprises a round head configured to engage the circular seat; Assembly. 26. 23. The assembly of claim 22 for securing an adjacent complete vertebra.   Each of the end plates is a flange defining the end face, and Comprising the flange extending outwardly from   The connecting means is an arc integral with the flange and projecting from the cylindrical portion. An adjacent arm so that the arm can engage the longitudinal member. An assembly having a free end configured to extend beyond the entire vertebra. 27. 27. The assembly of claim 26 for securing adjacent complete vertebrae,   A second arm formed at the free end to receive the longitudinal member; One hole and a set screw hole formed at the free end so as to traverse the first hole. Define   The connection means has a set screw screwed into the set screw hole,   A tip wherein the set screw engages a longitudinal member extending through the first hole An assembly having: 28. In the space formed by the removed vertebrae between adjacent complete vertebrae To make an implant for vertebral replacement   A length that has both ends and is dimensioned to span a portion of the space between the complete vertebrae An alternative object having   That of the complete vertebra when the implant is interposed in the space A pair of end plates having end surfaces contacting each one, each of said end plates being Said pair of end plates having an engaging portion extending integrally from,   Engage the end plate with the replacement object at a variable position along the length of the replacement object Between the opposite ends of the replacement object and the engagement portions of each of the end plates. Vertebral replacement implant comprising: 29. 29. The vertebral replacement implant of claim 28, wherein the engaging means comprises a frontal implant. Meshes formed on the ends of the replacement object and on each of the end plate engaging portions A vertebral replacement implant, including an implant. 30. 29. The vertebral replacement implant of claim 28, wherein the replacement object is Means fixed to each of the end plates to prevent the engaging means from being disengaged. A vertebral replacement implant for preparation. 31. Intervening in the space formed by the removed vertebra between two complete vertebrae Vertebral replacement implants   A thin-walled cylinder defining a hollow interior, wherein the wall of the cylinder is Defining a plurality of holes having a total area at least equal to 25% of the outer surface area;   The cylindrical body has opposite ends having continuous threads formed at each of the opposite ends;   A pair of end plates, each of which has an implant interposed within said space. A flange that defines an end surface that contacts the respective one of the full vertebrae when retracted Formed by   Each of the end plates further comprises a cylindrical portion projecting integrally from the flange;   The cylindrical portion is engaged with the screws at both ends of the thin cylinder. Define continuous screws,   When each of the end plates is threadably engaged with the end plate, the meat A vertebral replacement implant defining a through hole communicating with the hollow interior of the thin cylindrical body; plant. 32. A vertebral replacement implant according to claim 31,   The cylindrical portion of each of the end plates has a length protruding from the end face;   A crimp cut formed by the cylindrical portion along a portion of the length of the cylindrical portion; Define the chip,   The cylindrical portion is deformed by the crimp notch, closing the notch, When the cylinder is threadably engaged with the cylindrical portion of the end plate, the periphery of the cylinder is Vertebral replacement implant wherein the outer circumference of the cylindrical portion in And 33. The vertebral replacement implant according to claim 2, wherein a part of the plurality of holes is provided. A vertebral replacement implant extending through the first screw of the replacement object. 34. A vertebral replacement implant according to claim 7, wherein the replacement object is hollow. Having a cylindrical wall defining the interior,   The cylindrical wall defines a plurality of through holes;   The hole communicates with the hollow interior of the replacement object to allow tissue into the replacement object. A vertebral replacement implant that promotes head growth. 35. 35. The vertebral replacement implant of claim 34, wherein a portion of the plurality of holes is provided. A vertebral replacement implant extending through the external thread of the replacement object.
JP51767296A 1994-12-09 1995-12-01 Adjustable vertebral body replacement Expired - Fee Related JP3732228B2 (en)

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US35356694A 1994-12-09 1994-12-09
US08/353,566 1994-12-09
PCT/US1995/015654 WO1996017564A1 (en) 1994-12-09 1995-12-01 Adjustable vertebral body replacement
US09/073,081 US6344057B1 (en) 1994-11-22 1998-05-05 Adjustable vertebral body replacement

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DE (3) DE69534978T2 (en)
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US5702453A (en) 1997-12-30
WO1996017564A1 (en) 1996-06-13
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AU4372596A (en) 1996-06-26
EP1077659B1 (en) 2004-04-07
EP0797418A4 (en) 2003-01-22
ZA9510445B (en) 1996-06-19
WO1999056675A1 (en) 1999-11-11
AU3871199A (en) 1999-11-23
EP1077659A1 (en) 2001-02-28
EP1512385A1 (en) 2005-03-09
EP0797418A1 (en) 1997-10-01
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ES2259169T3 (en) 2006-09-16
DE69916261T2 (en) 2005-04-14

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