JPH1014973A - Adhesive sheet for application on skin and first aid adhesive tape - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an adhesive sheet for application on skin, excellent in water resistance, adhesiveness at bent parts, prevention of residual paste, non- skin stimulation, proper expandability, stress relaxing ability and the like, and a first aid adhesive tape using the same. SOLUTION: The surface or rear of a support body obtained by mainly making polyvinyl chloride foam are made smooth or uneven to laminate an adhesive agent layer for application on skin on the uneven surface sides. An adhesive sheet for application on skin obtained preferably ranges from 50 to 300gf/19mm in terms of 5-10% modulus and a liquid absorbing pad is provided at the central range of the surface of the adhesive agent layer of the adhesive sheet to obtain a first aid adhesive tape. The average degree of polymerization of polyvinyl chloride is preferably about 700-1,500. When a plasticizer is added, adipic acid based polyester with the average molecular weight by weight of 600-2,200 is preferably used.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a pressure-sensitive adhesive sheet for applying to skin and an emergency bandage.

[0002]

2. Description of the Related Art A pressure-sensitive adhesive sheet for use in application to the skin is usually provided with a pressure-sensitive adhesive layer for application to the skin on one side of a support such as a plastic film or a cloth, and is used for emergency bandages and dressings. It is used for various purposes such as a skin surface fixing sheet and a patch containing a transdermal absorbent. Since all of these are used by directly attaching the pressure-sensitive adhesive layer to the skin surface, they are required to have excellent adhesiveness to the skin surface and non-irritating properties to the skin surface. These required characteristics are extremely important when sticking for a long time. In particular, in the case of an adhesive sheet for pasting the skin such as an emergency bandage, even when it is stuck to a bent part such as a finger joint or a knee joint, it maintains the skin adhesiveness, and is water resistant so that it does not fall off even when performing water work or taking a bath. Properties such as imparting properties, painlessness at the time of peeling, and no adhesive remaining on the skin surface after peeling are required.

[0003] Under such circumstances, a bandage of a polyvinyl chloride film as a support has been conventionally used for an emergency bandage or the like. However, in conventional emergency bandages using a polyvinyl chloride film, the added plasticizer migrates from the support into the adhesive layer, reducing the cohesive force of the adhesive layer, and causing the adhesive to adhere to the skin surface. Residue (paste residue) easily occurs. Further, when a polyvinyl chloride film is used, there is a problem that the film becomes hard when used in cold weather such as winter, and the sticking feeling is extremely impaired.

On the other hand, as an alternative material to the above-mentioned widely used polyvinyl chloride film, a material using a melt blown nonwoven fabric or a polyolefin film has been proposed. These are approaches to solving the above problems from the viewpoint of the material used for the support, and imparting flexibility and flexibility to the adhesive sheet for applying to the skin to provide skin adhesion, skin following properties, and skin non-irritating properties And so on.

[0005] However, when these are used as supports, for example, when processing from a sheet to an emergency plaster, there arises a problem that processing is inferior due to excessive elongation, or punching is inferior due to being too soft. I can't say anything. Further, there is a problem that the balance between the flexibility and the mechanical strength is not sufficient, and that when the film is wound around a finger and peeled off, the substrate tends to be torn.

[0006]

Accordingly, the present invention has been intensively studied in order to solve the above-mentioned problems of the conventional pressure-sensitive adhesive sheet for skin application, and as a result, a support obtained by foaming mainly polyvinyl chloride is obtained. By making the front and back surfaces of the body smooth and uneven, and by laminating an adhesive layer for sticking the skin on the uneven surface side, water resistance, bending part adhesion, adhesive residue prevention, skin non-irritating, moderate The present inventors have found that a pressure-sensitive adhesive sheet for applying to the skin and an emergency plaster having elasticity, stress relaxation, and mechanical strength can be obtained, and have completed the present invention.

[0007]

That is, the present invention provides a foamed foam mainly composed of polyvinyl chloride, which has a rough surface and a smooth surface on the front and back surfaces, and adheres the skin to the rough surface of the support. And a pressure-sensitive adhesive sheet for sticking on the skin, wherein the pressure-sensitive adhesive layer is laminated.

Further, the present invention provides an emergency bandage which is provided with a liquid-absorbent pad in the center area of the surface of the pressure-sensitive adhesive layer in the pressure-sensitive adhesive sheet for skin application.

[0009]

BEST MODE FOR CARRYING OUT THE INVENTION The support used for the pressure-sensitive adhesive sheet for adhering to the skin and the first-aid adhesive plaster of the present invention has a pressure-sensitive adhesive layer to be described later laminated and held on one side with good anchoring property, and is mainly made of polyvinyl chloride. It was a foamed structure. As the polyvinyl chloride to be used, the average degree of polymerization is 700 to 150 from the viewpoint of appropriately adjusting the mechanical strength of the obtained foam.
It is preferable to use those having 0, preferably 800 to 1100. If the average degree of polymerization is too large, foaming becomes non-uniform, and a uniform foam may not be obtained. When the average degree of polymerization is small, the appearance and homogeneity of the foam are good, but the mechanical strength tends to be poor.

The support used in the present invention may contain the following plasticizers, foaming agents, stabilizers and the like in addition to the polyvinyl chloride.

As a plasticizer generally used, a plasticizer which is relatively inexpensive and has a high plasticizing effect is preferable in practical use. Therefore, a low-molecular-weight phthalate-based plasticizer and a high-molecular-weight plasticizer are often used in combination. When the phthalate ester-based low-molecular plasticizer is incorporated, the resulting plasticizer has a sufficient plasticizing effect on the support, but the low-molecular-weight plasticizer acts on the lamination interface with the pressure-sensitive adhesive layer laminated on the support and the pressure-sensitive adhesive layer. The plasticizer migrates. As a result, anchor breakage occurs between the support and the adhesive layer,
In some cases, the cohesive force of the pressure-sensitive adhesive layer is reduced to cause an adhesive residue phenomenon, which is not preferred in the present invention.

Accordingly, as a plasticizer that can be preferably used in the present invention, an adipic acid-based polyester plasticizer can be mentioned. The weight average molecular weight is 600-2.
It is preferable to use those having a range of 200. The adipic acid-based polyester plasticizer also slightly migrates into the pressure-sensitive adhesive layer, as in the case of the phthalate-ester plasticizer, but the migration does not significantly reduce the cohesive force. Since the layer gives a soft feeling, it has an effect of reducing pain at the time of peeling from the skin surface. Such adipic acid-based polyester plasticizers can be used alone or in combination with a small amount of a commonly used organic ester plasticizer.

The foaming agent is necessary for obtaining a foam, and only a part of the decomposition product is present in the finally obtained foam. That is, the foaming agent used in the present invention causes a decomposition reaction by heating to generate a gas such as a nitrogen gas or a carbon dioxide gas, and the gas forms a foamed structure. As such a foaming agent, those generally used in the production of leather, wallpaper (cloth), and the like can be used, and specifically, an azo foaming agent such as azodicarbonamide is optimal.

Further, the stabilizer plays an important role in obtaining a foam, and heat stabilizers and foam inhibitors known per se can be used. Among these, calcium / zinc-based stabilizers and the like are useful as those which can be preferably used for application to the skin as in the present invention.

[0015] The support used in the present invention, in addition to the above materials,
For example, various fillers, pigments and dyes as coloring agents, and the like can be appropriately compounded.

As a method for obtaining the support of the present invention from the above materials, polyvinyl chloride is mainly used as described above,
A plasticizer, a foaming agent, and a stabilizer are uniformly mixed at a low temperature (for example, 40 ° C. or lower) to form a plastisol, and a base material having heat resistance that can withstand the high temperature (for example, about 170 to 220 ° C.) After coating on top, there is a method of heating and foaming. As the heat-resistant substrate to be used, specifically, a heat-resistant polyethylene resin film (or sheet)
And a laminated film (or sheet) of paper and clay coat resin, a laminated film (or sheet) of paper and heat-resistant polyethylene resin film, and a polyester film (or sheet). The plastisol-coated surface of these substrates can be subjected to a silicone treatment as necessary to improve releasability, or a fine embossed surface can be applied to the surface of a foam obtained by embossing. .

The support of the present invention obtained as described above has a flat surface on the side in contact with the heat-resistant substrate at the time of manufacture, and the other surface has an uneven surface on which unevenness is formed by foaming. , Having a thickness of about 100 μm to 1 mm. In addition, the flat surface in the present invention does not mean a completely smooth surface, but may have fine pores on the surface by foaming, or may be finely embossed by matting. That is, the flat surface means a surface having smoothness by touching with a finger.
On the other hand, the unevenness means that the unevenness can be clearly observed by visual inspection or finger touch, and does not include the one where the unevenness cannot be confirmed without means such as an optical microscope.

In the pressure-sensitive adhesive sheet and the first-aid adhesive plaster of the present invention, a pressure-sensitive adhesive layer to be applied to the skin is laminated on the uneven surface side of the foam support to a thickness of about 20 to 100 μm. As the pressure-sensitive adhesive that can be used, natural rubber-based and synthetic rubber-based (styrene / isoprene (or butadiene) / styrene copolymer, styrene / butadiene copolymer, and the like) as long as they are so-called medical pressure-sensitive adhesives. , Acrylic (copolymers containing alkyl acrylate or alkyl methacrylate as main component), silicone (polyorganosiloxane, etc.), vinyl ester (copolymer using vinyl acetate as monomer) ) And vinyl ether-based pressure-sensitive adhesives. Of these, natural rubber-based and synthetic rubber-based pressure-sensitive adhesives not only have a large adhesive strength to the skin surface, but also have a small decrease in cohesive force and a change in adhesive properties even when the plasticizer migrates from the support. This is preferable because it is small. On the other hand, the acrylic pressure-sensitive adhesive is subjected to internal crosslinking or external crosslinking, for example, by increasing the gel fraction to 40% by weight or more, so that the skin adhesive strength is slightly lowered. No decrease in cohesive force is observed just by imparting a soft feeling to the agent layer, and the effect of relaxing skin irritation at the time of peeling is exhibited.Therefore, in the case of the acrylic pressure-sensitive adhesive as described above, the sticking site is It is preferable to use it for an adhesive sheet to be stuck to a relatively flat part instead of a bent part.

In the present invention, the pressure-sensitive adhesive layer is laminated on the uneven surface of the foam. However, in order to improve the anchoring force, it is preferable to provide an anchor coat layer on the uneven surface of the foam on which the pressure-sensitive adhesive layer is laminated. . As such an anchor coat layer, specifically, a resin obtained by grafting an acrylic polymer onto natural rubber can be used.

The thus obtained pressure-sensitive adhesive sheet for applying to the skin of the present invention is preferably selected from materials so that the modulus of 5 to 10% is preferably in the range of 50 to 300 gf / 19 mm width. By adjusting the modulus to this range, uncomfortable feeling during sticking is reduced, and sticking feeling is improved. In addition, even if it is attached to a bent portion, it has an appropriate elasticity, so that it has good skin followability and is hardly peeled off.

The pressure-sensitive adhesive sheet for application to the skin of the present invention has the above-mentioned constitution, but can be used as an emergency bandage by providing a liquid-absorbing pad in the central region of the surface of the pressure-sensitive adhesive layer. As the absorbent pad, for example, a gauze or a cotton cloth, a nonwoven fabric, a composite product of absorbent cotton and nonwoven fabric, a composite product of absorbent cotton and a knitted net can be used, and absorbs exudate from a wound portion,
Moreover, it is preferable because the wound can be protected.

In order to prevent the surface of the pressure-sensitive adhesive layer from being contaminated, the surface of the pressure-sensitive adhesive layer of the pressure-sensitive adhesive sheet and the first-aid bandage of the present invention may be covered with a known separator until use. preferable.

Further, the pressure-sensitive adhesive sheet for adhering to skin and the emergency bandage of the present invention can be subjected to a printing treatment on all or a part of the exposed surface of the support. The printing layer formed by the printing process can improve the abrasion resistance of the surface of the support and the slipperiness. In other words, if the slipperiness is poor, the end of the sheet is likely to be turned (peeled off) due to the rubbing with clothes or the like during use by sticking to the skin surface.
Therefore, these drawbacks can be eliminated by forming the printing layer on the exposed surface of the support by heat fusion or coating.

As the printing layer, an acrylic resin, a butyral resin, a polyvinyl chloride resin, a vinyl chloride / vinyl acetate copolymer resin, ethyl cellulose, polyurethane or the like can be used. For this purpose, it is preferable to apply a silicone-based or fluorine-based water-repellent agent on the printed layer after forming it.

In addition, since the support in the present invention is a foam having closed cells, it has a feeling, flexibility, cushioning property, and warm feel. This may cause skin irritation and the like. Therefore, in such a case, it is preferable to perform a perforation treatment on the support and the pressure-sensitive adhesive layer to such an extent that the mechanical strength is not reduced. To perform the perforation treatment, a method using a perforation roll, a method such as punching, or laser irradiation can be used.
mm.

[0026]

EXAMPLES Examples of the present invention will be shown below, and will be described more specifically. Hereinafter, "part" in the text means "part by weight", and "%" means "% by weight".

<Production of foam> The polyvinyl chloride, plasticizer (adipic acid-based polyester), foaming agent (azodicarbonamide) and stabilizer (calcium / zinc-based) shown in Table 1 were blended at 40 ° C. The resulting plastisol was uniformly mixed and the resulting plastisol was coated on the embossed and silicone-treated polyester film with a coating thickness of 150 μm.
m, and dried with hot air at 180 ° C. for 2 minutes to produce a foam. In the composition of Comparative Example 1, foaming was large and non-uniform, and a uniform foam sheet could not be obtained. Therefore, no pressure-sensitive adhesive sheet was produced.

<Adhesive> As the rubber-based adhesive, natural rubber 100 parts, styrene / butadiene copolymer rubber 100
Parts, terpene resin 170 parts, low molecular weight isoprene (M
(w: 30000) and 100 parts of a stabilizer (bisphenol) were uniformly mixed in toluene to adjust the solid content concentration to 25% to obtain an adhesive solution.

As the acrylic pressure-sensitive adhesive, 65 parts of nonyl acrylate, 30 parts of vinyl acetate, 5 parts of acrylic acid
The copolymer was copolymerized in ethyl acetate as a polymerization solvent to obtain a pressure-sensitive adhesive solution having a solid content of 35%.

<Preparation of Pressure-Sensitive Adhesive Sheet for Skin Application> An anchor coat layer was formed on the uneven surface of the foam of each of Examples and Comparative Examples shown in Table 1 (the surface opposite to the side that was in contact with the substrate at the time of production). A 2 μm coating of a graft resin of natural rubber / acrylic polymer was applied.

On the other hand, the pressure-sensitive adhesive solution prepared above was applied on a separator having one surface peeled with a silicone resin so that the thickness after drying was about 40 μm, and dried to form a pressure-sensitive adhesive layer.

Then, the obtained pressure-sensitive adhesive layer was laminated on the foamed anchor coat layer on which the anchor coat layer was formed as described above, to prepare a pressure-sensitive adhesive sheet for skin application.

[0033]

[Table 1]

The properties of the pressure-sensitive adhesive sheet for application to the skin of the present invention prepared as described above were measured as follows, and the results are shown in Table 2. Table 3 shows, as a reference example, characteristic values of a polyvinyl chloride film having a thickness of 80 μm on which the anchor coat layer and the rubber-based pressure-sensitive adhesive layer described in Example 1 were formed.

<Thickness and Expansion Ratio> The thickness of the foam was measured using a 1/1000 dial gauge according to JISZ0237. Further, the ratio of the thickness after foaming to the thickness at the time of film coating was measured and defined as a foaming ratio.

<Adhesive Strength> A test piece having a width of 19 mm and a length of 150 mm was prepared, attached to a phenol resin laminate, and then subjected to JISZ0237 using a low-speed extension tensile tester.
A 180-degree peeling test was performed at a tensile speed of 300 mm / min according to the above. The measurement was performed at 23 ± 2 ° C. and 65 ± 2 ° C.
The test was performed under the condition of 15% relative humidity.

<Modulus, tensile strength and elongation>
A test piece having a width of 150 mm and a length of 150 mm was prepared.
The measurement was performed at a tensile speed of 300 mm / min according to ISZ0237. The measurement was performed at 23 ± 2 ° C. and 65 ± 15% relative humidity.

[0038]

[Table 2]

[0039]

[Table 3]

Next, the pressure-sensitive adhesive sheet for pasting skin obtained in Examples 1 to 3, Comparative Example 2 and Reference Example was 5 cm × 5 cm.
(25 cm ² ), and this was affixed to the lower arm inner side A (a part that is prone to rash) and elbow B (bending part) of 12 healthy persons, and the skin adhesion and sticking feeling after 24 hours. (Discomfort), fog and adhesive residue during peeling were evaluated,
Table 4 shows the results. The rash was evaluated only on the inner side of the lower arm.

[0041]

[Table 4]

The pressure-sensitive adhesive sheet for pasting the skin obtained in Examples 1 to 3, Comparative Example 2 and Reference Example was 19 mm × 72 mm.
Cut to the size of mm, 16mm × in the center area of the adhesive layer
A gauze pad having a size of 20 mm was provided to prepare an emergency bandage.

The bandage samples thus prepared were wrapped around the second joint of the fingers of 12 healthy persons, and evaluated for skin adhesion, sticking feeling and adhesive residue, and the results are shown in Table 5. In addition, the sticking time was set to 8 hours, and daily water work was performed for evaluation.

[0044]

[Table 5]

[0045]

As described above, the pressure-sensitive adhesive sheet and the first-aid plaster of the present invention use a specific foam as a support, so that the pressure-sensitive adhesive sheet and the first-aid adhesive plaster of the present invention can be compared with those using a conventional polyvinyl chloride film as a support. Even with excellent skin adhesion,
It is excellent in water resistance, adhesiveness to bent portions, prevention of adhesive residue, non-irritating skin, and the like. In particular, the effect of the present invention can be maximized by using it for an emergency bandage.

 ──────────────────────────────────────────────────の Continuation of front page (72) Inventor Osamu Ohira 1-1-2 Shimohozumi, Ibaraki-shi, Osaka Nitto Denko Corporation

Claims (6)

[Claims] 1. A support comprising a foam mainly composed of polyvinyl chloride having an uneven surface and a smooth surface on its front and back surfaces, and an adhesive layer to be adhered to the skin laminated on the uneven surface side of the support. A pressure-sensitive adhesive sheet for adhering to skin. 2. The average degree of polymerization of polyvinyl chloride is 700 to
The pressure-sensitive adhesive sheet for application to skin according to claim 1, which is 1500. 3. A foam comprising a polyvinyl chloride as a main component, a plastisol containing a plasticizer, a foaming agent and a stabilizer added thereto on a releasable substrate, followed by heating and foaming. The pressure-sensitive adhesive sheet for adhering to the skin according to claim 1. 4. The plasticizer has a weight average molecular weight of 600 to 220.
The pressure-sensitive adhesive sheet for application to the skin according to claim 3, which is adipic acid-based polyester of No. 0. 5. The method according to claim 1, wherein the modulus of 5 to 10% is 50 to 30.
The pressure-sensitive adhesive sheet for application to the skin according to claim 1, which has a width of 0 gf / 19 mm. 6. An emergency bandage which is provided with a liquid-absorbent pad in the central area of the surface of the pressure-sensitive adhesive layer in the pressure-sensitive adhesive sheet for skin application according to claim 1.