JPH10139677A - Skin lotion - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a skin lotion used for completely curing dermatophytosis, capable of treating not only obstinate dermatophytosis but also common skin disease by including components consisting essentially of a specific mixture of Chinese crude medicine. SOLUTION: This skin lotion is obtained by using Chusoyaku (Chinese crude medicine) consisting essentially of Indigo pulverata Levis, Sophora flvescens Aitin and Plygoni multiflori Radix, adding the Chusouyaku to one or more than two kinds selected from a fat, vaseline, a wax, a natural resin, a higher alcohol, a higher fatty acid as a substrate and kneading the mixture to form an ointment, or adding the Chusoyaku to powder of magnesia or zinc oxide, and starch and mixing them to form powdered drug.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a Chinese herbal medicine-based external preparation for skin which has a hemostatic action as well as a disinfecting action.

[0002]

2. Description of the Related Art At present, skin external preparations that are widely and widely used include powders and pastes in addition to liquids and ointments.
And its composition is used as a base material such as an ointment such as fat, petrolatum, wax, natural resin, higher alcohol, a mixture of one or more higher fatty acids or a powder such as a mixture of zinc white and starch, and a fragrance. , A disinfectant, a disinfectant, a neutralizing agent, a bonding agent, a stabilizer, and the like. As an external preparation for the skin, salicylic acid, acetic acid, camphor, boric acid and the like, which have strong bactericidal properties, have been known as therapeutic agents for athlete's foot from ancient times (for example, JP-A-52-44226). Several products using folk medicines and herbal medicines have also been proposed.
Japanese Patent No. 53-28965 proposes a composition comprising cluster amaryllis, chickweed, dokudami, mandarin peel, rhubarb, etc., and Japanese Patent Application Laid-Open No. 57-145806 discloses a composition using a hot water flower and an aloe extract as a raw material. JP-A-3-271231 discloses an athlete's foot remedy containing a wasabi component.

[0003]

However, dermatoses, especially athlete's foot, are complicated and are caused by stubborn Trichophyton, which forms a hard shell in the skin and sleeps as spores. It is a nuisance that begins to work under extreme temperatures and humidity, erupts, is painful, sometimes feverish, and in severe cases even makes it difficult to walk. Therefore, many studies have been made and various therapeutic agents have been developed so far, but few of them show strong medicinal effects to cure them.

[0004] The present invention not only treats stubborn athlete's foot,
A topical medicine effective for general dermatosis, which aims at complete eradication of athlete's foot by using a specific mixture of Chinese herbal medicine as a main component as its component composition.

[0005]

Means for Solving the Problems The gist of the present invention is to consist of a medicinal plant anther (chusouyaku) whose main component is Seisui, Kujin, and Shuu. It is characterized by. The anthers of the medicinal herbs are the same as the medicines, meaning Chinese herbs.

[0006] One or a mixture of two or more of fats, petrolatum, waxes, natural resins, higher alcohols and higher fatty acids, which are conventionally used as ointment bases, is added to the medicinal herbs. Flavors, pigments, bactericides, disinfectants, neutralizing agents, etc. are added as appropriate. As powders, mixtures of zinc white and starch are known, and these are also useful as the powder base material of the present invention.

[0007] Here, Ao-Mizuzumi is a Japanese grape that is made by adding water to a large green leaf (daiseiyo), crushing it, adding lime water and floating the powder of blue (indigo) floating on the surface. Inhibits cocci. It is good for sterilization and chronic eczema.

[0008] Bitter ginseng is a perennial herb native to various parts of Japan and its roots are called kujin (Sophorae Radix) and include alkaloids. It is known as a stomach and anthelmintic in Chinese medicine.

[0009] Furthermore, Shushu is also known as Kashu.
The same applies to the roots of turdokudami. It is a herbaceous vine that grows naturally in China and various parts of Japan. It is used in Chinese medicine for insemination, tonic, and laxative. The components contained are anthraquinone derivatives and the like.

[0010] In the composition, Ao-Mizuzumi 15-35%, bitter ginseng 15-35
%, 3 to 20% of Shubo, and 100% with other medicinal anthers and bulking agents. Other medicinal anthers are added to promote the effects of the above three components, and include bitter stomach medicine Huangkashia, tonic medicine ginseng, licorice and the like.

The mixing ratio of the mesophyll anther and the base material can be varied widely for adults, for infants or depending on the type of skin disease to be treated, but is usually in the range of 2 to 50%, preferably 5 to 30%. Is done.

[0012]

BEST MODE FOR CARRYING OUT THE INVENTION The skin external preparation composition of the present invention is obtained by selecting a valuable crude drug, extracting it by a scientific method, and purifying it as described above. Table 1 shows an example of a specific production method and composition.

[0013]

[Table 1] Ao-Mizuzumi 30% Caricature 30% Shuwasu 10% Other anthers 30%

[0014] These components, which have been thoroughly dried, are mixed and pulverized, and 15
It should be 0 mesh pass powder. Further, a part thereof is steamed and carbonized to obtain a black-gray fine powdery mesophyll anther composition.
The content of heavy metals and the like in this composition is as shown in Table 2, and was hardly detected. The mesophyll anther composition is used as it is as a powder, and an undiluted solution obtained by adding an approximately 5-fold amount of water to the extract and filtering the extract may be used.

[0015]

[Table 2] Total mercury 0.0005 ppm or less Lead 0.10 ppm or less Cadmium 0.05 ppm or less Arsenic 0.05 ppm or less Magnesium 2200 mg / kg Calcium 1300 mg / kg Potassium 510 mg / kg Sodium 570 mg / kg Iron 390 mg / kg

[0016] When the medicinal plant anther composition (10 parts) is made into an ointment, it is prepared by kneading one or a mixture (90 parts) of fat, petrolatum, wax, natural resin, higher alcohol, and higher fatty acid. I do. When a powder preparation is used, the mixture is added to and mixed with a mixed powder of 45 parts of zinc white and 45 parts of starch with respect to 10 parts of the medicinal anther composition to prepare a powdery external preparation for skin. The use of the composition for external use on the skin is simple, and it may be rubbed into the affected area in the same manner as a normal ointment. However, during use, it is necessary to cut off green onions, raw garlic, and raw radish, which are contraindicated with the crude drug of the skin external preparation composition. Hereinafter, specific skin external preparations will be described with reference to Examples.

[0017]

EXAMPLE A heavy magnesia powder having the composition shown in Table 3 was prepared. First, a mixture of Qingzhu, Tosin, Shubo and Rhubarb fine powder is used to prepare a medicinal anther composition. On the other hand, a powder preparation was prepared by adding some fennel oil to heavy magnesia as a powder extender, and this was mixed and homogenized with the above-mentioned anther composition powder to give a powder preparation.

[0018]

[Table 3] Ao-Mizuzumi 60g Bitter ginseng 60g Necklace 20g Subtotal 140g Rhubarb fine powder 150g Heavy magnesia 700g Fennel oil 10g Total 1000g

The above-mentioned powder was rubbed into the athlete's foot area between the toes and on the sole of the foot after bathing, and the socks were removed. The treatment was repeated daily. Within 2 to 3 days, at most within 1 week. Completely cured. When the affected part was dry athlete's foot, the eruption disappeared from the second day, and one week later, the epidermis peeled off and became red skin, and the skin was completely cured. Even when the affected area is moist, the rash disappears from the second day, and after that, it is moist for a few days, but on the third to the fourth day, the affected area is dry and the epidermis peels off, and red fresh skin is formed. It was later found not to recur. At least 20 cases of these symptoms have been confirmed so far.

With the composition shown in Table 4, a yellow ointment using yellow wax and vegetable oil was prepared. First, yellow wax and vegetable oil were melt-mixed and then cooled, and before starting to solidify, the above-mentioned anther composition was mixed and stirred to obtain an ointment. When this yellow ointment was applied to the affected part of athlete's foot in the same manner as in the powder of Example 1, the athlete's foot could be treated in the same manner as in Example 1. This ointment was confirmed to be highly effective against insect bites.

[0021]

[Table 4] Aozumi 20g Bitter ginseng 20g Shuwu 20g Licorice 40g Subtotal 100g Yellow wax 300g Vegetable oil 600g Total 1000g

A white ointment having the composition shown in Table 5 was prepared.
Using a mixture of dehydrated lanolin, white wax and white petrolatum as an ointment, white wax is melted on a hot water bath, dehydrated lanolin and white petrolatum are added thereto, and the mixture is heated to a liquid state. The powder was mixed and stirred until it solidified, and then allowed to cool. When a mixture of 70 g of dehydrated lanolin and 200 g of zinc white is further added to 730 g of this white ointment, the mixture can be used as a zinc white ointment containing anthers.

[0023]

[Table 5] Ao Mayuzumi 40 g Bitter ginseng 40 g Shuwasu 20 g Huangbashi 50 g Subtotal 150 g Dehydrated lanolin 50 g White wax 50 g White petrolatum 750 g Total 1000 g

With the composition shown in Table 6, zinc white and starch were added to obtain a skin external preparation useful as a powder.

[0025]

[Table 6] Aozumi 30g Ginseng 30g Shuwasu 10g Carrot powder 30g Subtotal 100g Zinc flower 450g Starch 450g Total 1000g

The white ointment shown in Table 5 and the zinc white ointment to which zinc white was added, and the zinc white powder shown in Table 6 were all used for the treatment of Trichophyton such as athlete's foot due to the presence of the mesophyll anther composition. It has been found that it is useful for the treatment of various skin diseases such as insect bites, burns, eczema, and the like by application to various affected areas.

[0027]

As is clear from the above examples, the external preparation for skin of the present invention has no side effects at all since it contains natural medicinal anthers as a main component, and exhibits excellent disinfecting and hemostatic effects. It is particularly effective in treating athlete's foot medicine, insect bites, burns, eczema, etc.

Claims (3)

[Claims] 1. An external preparation for skin, comprising a medicinal anther consisting mainly of Aozumitsu, Tokujin and Shuwo. 2. Addition and kneading of a medicinal herb mainly composed of Aozumi, Bushi, Shubo to one or a mixture of fat, vaseline, wax, natural resin, higher alcohol and higher fatty acid as a base material. An external preparation for skin characterized by being made into an ointment. 3. An external skin preparation comprising adding and mixing a medicinal herb mainly composed of Aoizumi, Bushi, and Shuwo to heavy magnesia or zinc white powder as a base material and starch to form a powder. Agent.