JPH0999062A - Bubble detector - Google Patents

Bubble detector

Info

Publication number
JPH0999062A
JPH0999062A JP31171095A JP31171095A JPH0999062A JP H0999062 A JPH0999062 A JP H0999062A JP 31171095 A JP31171095 A JP 31171095A JP 31171095 A JP31171095 A JP 31171095A JP H0999062 A JPH0999062 A JP H0999062A
Authority
JP
Japan
Prior art keywords
circuit
pass filter
ultrasonic transducer
output signal
hpf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP31171095A
Other languages
Japanese (ja)
Inventor
Takamasa Nogami
高正 野上
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toray Engineering Co Ltd
Original Assignee
Toray Engineering Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Engineering Co Ltd filed Critical Toray Engineering Co Ltd
Priority to JP31171095A priority Critical patent/JPH0999062A/en
Publication of JPH0999062A publication Critical patent/JPH0999062A/en
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00Indexing codes associated with group G01N29/00
    • G01N2291/04Wave modes and trajectories
    • G01N2291/044Internal reflections (echoes), e.g. on walls or defects

Landscapes

  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Geophysics And Detection Of Objects (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • External Artificial Organs (AREA)

Abstract

PROBLEM TO BE SOLVED: To surely detect bubbles mixed into the sampling circuit of a blood circuit, etc. SOLUTION: This device is provided with an ultrasonic vibration driving circuit 1, ultrasonic vibrator 2 for transmission, ultrasonic vibrator 3 for reception, tube 4 consisting of the sampling circuit, amplifier circuit 5, 1st high-pass filter(HPF) 6, rectifier circuit 7, low-pass filter(LPF) 8, 2nd HPF 9 and comparator circuit 10. Then, the 1st HPF 6 passes only a high frequency component in the output signal of the amplifier circuit 5 and the 2nd HPF 9 passes a change component in the output signal of the LPF 8. Further, the comparator circuit 10 detects only a remarkable change component in the change component passed through the 2nd HPF 9. Then, since the influence of noises or small bubbles can be removed by amplifying a signal received by the ultrasonic vibrator 3 for reception and passing only its specified component through the various filters, bubbles can be surely detected.

Description

【発明の詳細な説明】Detailed Description of the Invention

【0001】[0001]

【発明の属する技術分野】本発明は、気泡検知器、特
に、体外に構成した血液回路から再び人体に返血する装
置(例えば、人工透析装置等)において用いるに好適な
気泡検知器に関するものである。
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a bubble detector, and more particularly to a bubble detector suitable for use in a device for returning blood to a human body again from a blood circuit constructed outside the body (for example, an artificial dialysis device). is there.

【0002】[0002]

【従来の技術】従来、気泡検知器は、人工透析装置等に
おいて広く実用に供されている。すなわち、例えば、人
体への返血路であるチューブ内を流れる血液中に混入し
た気泡を検知する為に、前記チューブを挟むように発信
用超音波振動子と受信用超音波振動子とを対向させて装
着し、かかる発信用超音波振動子から連続した超音波を
発信すると共にチューブ内を流れる血液を介して、前記
超音波を受信用超音波振動子で受信し、血液中の気泡を
超音波が通過することで低下する前記受信信号レベルの
変化を検出する気泡検知器が広く実用に供されている。
2. Description of the Related Art Conventionally, bubble detectors have been widely put to practical use in artificial dialysis machines and the like. That is, for example, in order to detect air bubbles mixed in blood flowing through a tube that is a blood return path to the human body, the ultrasonic transducer for transmission and the ultrasonic transducer for reception are opposed so as to sandwich the tube. The ultrasonic transducer for transmission transmits continuous ultrasonic waves, and the ultrasonic transducer for reception receives the ultrasonic waves through the blood flowing in the tube, and ultrasonic waves are generated in the air bubbles in the blood. The air bubble detector that detects the change in the received signal level that decreases as a result of passage is widely used.

【0003】[0003]

【発明が解決しようとする課題】しかし、この種の気泡
検知器は、次のような欠点を有していた。すなわち、受
信用超音波振動子からの信号レベルが非常に小さく、か
つ、信号線のインピーダンスが高い為、AC100V電
源の持つ周波数など、様々な電気的雑音の影響を受け易
く、この雑音は、しばしば無視できないレベルとなる。
加えて、超音波振動子の特性のばらつきによる信号レベ
ルの違いも大きい。その為、受信用超音波振動子からの
信号処理部において、どのレベルで気泡を検知するかが
非常に難しく、時には誤動作することがある。
However, this type of bubble detector has the following drawbacks. That is, since the signal level from the receiving ultrasonic transducer is very low and the impedance of the signal line is high, it is easily affected by various electric noises such as the frequency of the AC100V power supply, and this noise is often generated. It will be a level that cannot be ignored.
In addition, there is a large difference in signal level due to variations in the characteristics of the ultrasonic transducer. Therefore, it is very difficult at what level to detect bubbles in the signal processing unit from the receiving ultrasonic transducer, and sometimes malfunctions occur.

【0004】本発明は、このような欠点に鑑みて発明さ
れたものであり、確実に気泡を検知することができる高
精度の気泡検知器を得るべく鋭意検討の結果、後述する
ように、発信用超音波振動子を連続した矩形波で駆動す
る超音波振動駆動回路と、受信用超音波振動子により受
信した信号を増幅する増幅回路及びこの増幅回路の出力
信号のうち高周波成分のみを通過させる第1ハイパスフ
ィルタ等を備えることによって、かかる目的を達成し得
ることを見い出したものである。
The present invention has been invented in view of such drawbacks, and as a result of earnest studies to obtain a highly accurate bubble detector capable of reliably detecting bubbles, as will be described later, transmission is performed. Vibration driving circuit for driving the ultrasonic transducer for continuous rectangular waves, an amplifying circuit for amplifying the signal received by the receiving ultrasonic transducer, and passing only the high frequency component of the output signal of this amplifying circuit It has been found that such a purpose can be achieved by providing the first high-pass filter and the like.

【0005】[0005]

【課題を解決するための手段】すなわち、本発明に係る
気泡検知器は、試料回路を構成しているチューブを挟む
ように発信用超音波振動子と受信用超音波振動子とを装
着した気泡検知器において、前記発信用超音波振動子を
連続した矩形波で駆動する超音波振動駆動回路と、前記
受信用超音波振動子により受信した信号を増幅する増幅
回路と、前記増幅回路の出力信号のうち高周波成分のみ
を通過させる第1ハイパスフィルタと、前記第1ハイパ
スフィルタの出力信号を整流する整流回路と、前記整流
回路の出力信号を平滑する中低周波成分のみを通過させ
るローパスフィルタと、前記ローパスフィルタの出力信
号の変化成分を通過させる第2ハイパスフィルタと、前
記第2ハイパスフィルタを通過した変化成分のうち、大
きな変化成分のみを検出する比較回路とを備えたことを
特徴とするものである。なお、試料回路は血液回路であ
るのが好ましい。
That is, a bubble detector according to the present invention is a bubble detector in which a transmitting ultrasonic transducer and a receiving ultrasonic transducer are mounted so as to sandwich a tube forming a sample circuit. In the detector, an ultrasonic vibration drive circuit that drives the transmitting ultrasonic vibrator with a continuous rectangular wave, an amplifier circuit that amplifies a signal received by the receiving ultrasonic vibrator, and an output signal of the amplifier circuit. A first high-pass filter that passes only high-frequency components, a rectifying circuit that rectifies the output signal of the first high-pass filter, and a low-pass filter that passes only low- and medium-frequency components that smoothes the output signal of the rectifying circuit, A second high-pass filter that passes the change component of the output signal of the low-pass filter and a large change component of the change components that pass the second high-pass filter It is characterized in that a comparison circuit to be detected. The sample circuit is preferably a blood circuit.

【0006】[0006]

【発明の実施の形態】人工透析装置においては、人体に
返血する際に、血液中に気泡が混入して体内に運ばれる
のを防止する為に、血液中の気泡を検知する気泡検知器
を装着しているが、図1において、かかる気泡検知器の
一実施例を示す。
BEST MODE FOR CARRYING OUT THE INVENTION In an artificial dialysis device, a bubble detector for detecting bubbles in blood in order to prevent bubbles from being mixed into blood and carried into the body when returning to the human body. In FIG. 1, an embodiment of such a bubble detector is shown.

【0007】同図において、この気泡検知器は、超音波
振動駆動回路1と、発信用超音波振動子2と、受信用超
音波振動子3と、血液回路(試料回路)を構成している
チューブ4と、増幅回路5と,第1ハイパスフィルタ6
と、整流回路7と、ローパスフィルタ8と、第2ハイパ
スフィルタ9及び比較回路10とを備えている。
In the figure, this bubble detector comprises an ultrasonic vibration drive circuit 1, an ultrasonic oscillator 2 for transmission, an ultrasonic oscillator 3 for reception, and a blood circuit (sample circuit). Tube 4, amplifier circuit 5, first high-pass filter 6
A rectifier circuit 7, a low pass filter 8, a second high pass filter 9 and a comparison circuit 10.

【0008】なお、血液回路(試料回路)を構成してい
るチューブ4を挟むように発信用超音波振動子2と受信
用超音波振動子3とが対向せしめられて装着されている
が、発信用超音波振動子2は、発信用超音波振動子3の
共振周波数に等しい、すなわち、具体的には、1MHz
の連続した矩形波で駆動する超音波振動駆動回路1によ
り駆動される。
It should be noted that although the ultrasonic transducer 2 for transmission and the ultrasonic transducer 3 for reception are mounted so as to face each other so as to sandwich the tube 4 constituting the blood circuit (sample circuit), Ultrasonic transducer 2 is equal to the resonance frequency of transmitting ultrasonic transducer 3, that is, specifically, 1 MHz.
Is driven by the ultrasonic vibration drive circuit 1 which is driven by a continuous rectangular wave.

【0009】一方、受信用超音波振動子3は、チューブ
4内の血液を通過してきた超音波を受信し、そして、こ
の受信用超音波振動子3から出力される電気信号が、増
幅回路5により増幅され、以下、第1ハイパスフィルタ
6、整流回路7、ローパスフィルタ8、第2ハイパスフ
ィルタ9、比較回路10を経て所定の検出信号を得るこ
とができる。
On the other hand, the receiving ultrasonic transducer 3 receives the ultrasonic waves that have passed through the blood in the tube 4, and the electric signal output from the receiving ultrasonic transducer 3 is amplified by the amplifying circuit 5. Then, a predetermined detection signal can be obtained through the first high-pass filter 6, the rectifier circuit 7, the low-pass filter 8, the second high-pass filter 9, and the comparison circuit 10.

【0010】その際、受信用超音波振動子3と増幅回路
5間は、インピーダンスが高くて雑音が乗り易いが、受
信用超音波振動子3の共振周波数では、受信用超音波振
動子3の出力インピーダンスは非常に小さい為、雑音が
乗り難くなる。しかし、共振周波数より大きな周波数成
分では、増幅回路5に十分な増幅特性が無い為、信号周
波数に比べて低い周波数、特に電源周波数の雑音が問題
になる。そこで、増幅回路5の出力信号のうち信号成分
である高周波成分のみを通過させる第1ハイパスフィル
タ6を設け、これにより雑音成分を取り除いている。
At this time, the impedance between the receiving ultrasonic transducer 3 and the amplifying circuit 5 is high and noise is likely to be generated, but at the resonance frequency of the receiving ultrasonic transducer 3, the receiving ultrasonic transducer 3 has a resonance frequency. Since the output impedance is very small, it is difficult for noise to ride. However, with a frequency component larger than the resonance frequency, the amplification circuit 5 does not have sufficient amplification characteristics, and therefore, noise at a frequency lower than the signal frequency, particularly noise at the power supply frequency, becomes a problem. Therefore, the first high-pass filter 6 that passes only the high-frequency component that is the signal component of the output signal of the amplifier circuit 5 is provided to remove the noise component.

【0011】また、第1ハイパスフィルタ6の出力信号
を整流する整流回路7と、整流回路7の出力信号を平滑
する中低周波成分のみを通過させるローパスフィルタ8
とを設け、信号成分を直流信号に変えると共にローパス
フィルタ8によって、雑音成分や気泡のうち、人体に害
が無く再度、血液中に溶けてしまうような小さな気泡に
よる信号を減衰させている。
A rectifier circuit 7 for rectifying the output signal of the first high-pass filter 6 and a low-pass filter 8 for passing only the low and medium frequency components for smoothing the output signal of the rectifier circuit 7.
And the signal component is changed to a DC signal, and the low-pass filter 8 attenuates the noise component and bubbles, which are small bubbles that are dissolved in the blood again without harm to the human body.

【0012】また、ローパスフィルタ8の出力信号のレ
ベルは、発信用超音波振動子2又はは受信用超音波振動
子3の特性のばらつきにより大きく変動するので、信号
の変化成分のみを通過させる第2ハイパスフィルタ9を
設け、これにより、発信用超音波振動子2又は受信用超
音波振動子3の特性のばらつきによる信号レベルの変動
の影響を回避している。
The level of the output signal of the low-pass filter 8 fluctuates greatly due to variations in the characteristics of the transmitting ultrasonic transducer 2 or the receiving ultrasonic transducer 3, so that only the signal change component is passed. By providing the 2 high-pass filter 9, the influence of the fluctuation of the signal level due to the variation of the characteristics of the transmitting ultrasonic transducer 2 or the receiving ultrasonic transducer 3 is avoided.

【0013】更に、雑音や小さな気泡の影響を避ける
為、小さな変化は検出しないで、ある程度以上の変化を
捕らえる比較回路10を設け、これにより、気泡を確実
に検知し得るようにしている。
Further, in order to avoid the influence of noise and small air bubbles, a comparator circuit 10 is provided which detects a certain amount of change without detecting a small change, thereby making it possible to surely detect the air bubble.

【0014】よって、本発明に係る気泡検知器による
と、受信用超音波振動子により受信した信号を増幅し、
その特定成分だけを各種のフィルタを通過させるように
して雑音や小さな気泡の影響を除去できるので、確実に
気泡を検知することができる。
Therefore, according to the bubble detector of the present invention, the signal received by the ultrasonic transducer for reception is amplified,
Since the influence of noise and small bubbles can be removed by allowing only the specific component to pass through various filters, it is possible to reliably detect the bubbles.

【0015】以上、本発明に係る気泡検知器の一実施例
について述べたが、本発明においては、血液以外の他の
試料であってもよく、その場合においては、チューブ4
で所定の試料回路を構成すればよい。
Although one embodiment of the bubble detector according to the present invention has been described above, in the present invention, a sample other than blood may be used. In that case, the tube 4 is used.
The predetermined sample circuit may be configured with.

【0016】[0016]

【発明の効果】上述の如く、請求項1,2に記載の発明
によると、雑音や小さな気泡の影響を避けて確実に気泡
を検知することができ、特に、人工透析装置等の医療装
置において用いるに好適な高精度の気泡検知器を得るこ
とができる。
As described above, according to the first and second aspects of the present invention, it is possible to reliably detect air bubbles while avoiding the influence of noise and small air bubbles, and especially in medical devices such as artificial dialysis machines. A high-precision bubble detector suitable for use can be obtained.

【図面の簡単な説明】[Brief description of drawings]

【図1】本発明の一実施例に係る気泡検知器の構成を示
すブロック図である。
FIG. 1 is a block diagram showing a configuration of a bubble detector according to an embodiment of the present invention.

【符号の説明】[Explanation of symbols]

1 超音波振動駆動回路 2 発信用超音波振動子 3 受信用超音波振動子 4 血液回路(試料回路)を構成しているチューブ 5 増幅回路 6 第1ハイパスフィルタ 7 整流回路 8 ローパスフィルタ 9 第2ハイパスフィルタ 10 比較回路 1 ultrasonic vibration drive circuit 2 ultrasonic transducer for transmission 3 ultrasonic transducer for reception 4 tube constituting blood circuit (sample circuit) 5 amplification circuit 6 first high-pass filter 7 rectification circuit 8 low-pass filter 9 second High-pass filter 10 Comparison circuit

Claims (2)

【特許請求の範囲】[Claims] 【請求項1】 試料回路を構成しているチューブを挟む
ように発信用超音波振動子と受信用超音波振動子とを装
着した気泡検知器において、前記発信用超音波振動子を
連続した矩形波で駆動する超音波振動駆動回路と、前記
受信用超音波振動子により受信した信号を増幅する増幅
回路と、前記増幅回路の出力信号のうち高周波成分のみ
を通過させる第1ハイパスフィルタと、前記第1ハイパ
スフィルタの出力信号を整流する整流回路と、前記整流
回路の出力信号を平滑する中低周波成分のみを通過させ
るローパスフィルタと、前記ローパスフィルタの出力信
号の変化成分を通過させる第2ハイパスフィルタと、前
記第2ハイパスフィルタを通過した変化成分のうち、大
きな変化成分のみを検出する比較回路とを備えたことを
特徴とする気泡検知器。
1. A bubble detector in which an ultrasonic transducer for transmission and an ultrasonic transducer for reception are mounted so as to sandwich a tube constituting a sample circuit, and the ultrasonic transducer for transmission has a continuous rectangular shape. An ultrasonic vibration drive circuit driven by waves, an amplifier circuit that amplifies a signal received by the receiving ultrasonic vibrator, a first high-pass filter that passes only a high frequency component of an output signal of the amplifier circuit, and A rectifier circuit that rectifies the output signal of the first high-pass filter, a low-pass filter that smoothes the output signal of the rectifier circuit, and that passes only low- and medium-frequency components, and a second high-pass filter that passes the change component of the output signal of the low-pass filter. Bubble detection comprising a filter and a comparator circuit that detects only a large change component of the change components that have passed through the second high-pass filter. vessel.
【請求項2】 試料回路が血液回路であることを特徴と
する請求項1に記載の気泡検知器。
2. The bubble detector according to claim 1, wherein the sample circuit is a blood circuit.
JP31171095A 1995-10-04 1995-10-04 Bubble detector Pending JPH0999062A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP31171095A JPH0999062A (en) 1995-10-04 1995-10-04 Bubble detector

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP31171095A JPH0999062A (en) 1995-10-04 1995-10-04 Bubble detector

Publications (1)

Publication Number Publication Date
JPH0999062A true JPH0999062A (en) 1997-04-15

Family

ID=18020542

Family Applications (1)

Application Number Title Priority Date Filing Date
JP31171095A Pending JPH0999062A (en) 1995-10-04 1995-10-04 Bubble detector

Country Status (1)

Country Link
JP (1) JPH0999062A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005189003A (en) * 2003-12-24 2005-07-14 Ueda Japan Radio Co Ltd Integration system capable of flow rate measurement and bubble detection
JP2008020222A (en) * 2006-07-11 2008-01-31 Ngk Insulators Ltd Passage detection device of object
JP2010518395A (en) * 2007-02-06 2010-05-27 フレゼニウス メディカル ケア ホールディングス インコーポレーテッド An ultrasonic system for detecting and quantifying at least one of bubbles and particles contained in a flowing liquid

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005189003A (en) * 2003-12-24 2005-07-14 Ueda Japan Radio Co Ltd Integration system capable of flow rate measurement and bubble detection
JP2008020222A (en) * 2006-07-11 2008-01-31 Ngk Insulators Ltd Passage detection device of object
JP2010518395A (en) * 2007-02-06 2010-05-27 フレゼニウス メディカル ケア ホールディングス インコーポレーテッド An ultrasonic system for detecting and quantifying at least one of bubbles and particles contained in a flowing liquid
EP2126557A4 (en) * 2007-02-06 2016-03-30 Fresenius Med Care Hldg Inc Ultrasonic system for detecting and quantifying of air bubbles/particles in a flowing liquid

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Effective date: 20050412