JPH0995437A - Aqueous composition for cleaning periphery of anus - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain an aqueous composition for cleaning the periphery of an anus, capable of preventing the multiplication of seproshytes during storage and hygienically maintaining the anus and its periphery, and not causing skin roughness and allergy. SOLUTION: This aqueous composition for cleaning the periphery of anus contains an antimicrobial agent and a pH-buffering solution in an amount required for controlling the pH to 4.0-6.0. The volume of a 1/100 N aqueous sodium hydroxide solution required for raising the pH of 30ml of the 10 times diluted solution of the aqueous composition for cleaning the periphery of the anus is 2-10ml.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a water-based anal anus cleansing composition and a perianal cleaning material impregnated with the composition, which has a pH of skin
It is maintained at a weak acidity close to H, suppresses the growth of various bacteria, and has less irritation to the skin.

[0002]

2. Description of the Related Art As a site in the human body where treatment by application of a drug or daily care is difficult, there are mucous membrane parts such as oral cavity, vagina, nasal cavity and anus. it can. Of these, the anus is not only difficult to reach, but it is also inaccessible to the eyes, and thus it is difficult to provide daily care from a mental point of view. For this reason,
It is relatively easy to become unsanitary, and the prevalence of diseases such as hemorrhoids is considerably high. Therefore, it is necessary to clean the anus and its surroundings and keep the anus and its surroundings hygienic.

In addition, since infants and old people cannot excrete themselves, they often wear diapers regularly, but the skin in contact with the diaper is affected by the excretion in the diaper.
Often causes dermatitis (diaper rash). Therefore, also from the viewpoint of suppressing the occurrence of such dermatitis (diaper rash), it is necessary to clean the skin, particularly around the anus, and keep it hygienic.

The anus and its surroundings are generally wiped by wiping off foreign substances such as stool adhering to the anus and its surroundings with a toilet paper or a tissue paper. Such a wiping operation is performed. It is not possible to remove foreign matters such as stool sufficiently only by itself.

Conventionally, for cleaning the anus and its surroundings,
JP-A-61-85311, JP-A-2-15292
No. 0, Japanese Patent Application Laid-Open No. 4-99717 and Japanese Patent Application Laid-Open No. 4-99717.
Wiping with a wiping agent containing an antibacterial agent described in Japanese Patent No. 53531 is performed. Further, it is also possible to impregnate a cloth-like material or the like with the cleaning agent described in the above publication and use it as a cleaning material around the anus.

Further, in Japanese Patent Laid-Open No. 64-38018, a pH value of 4.
A milky skin cleansing agent adjusted to 0 to 6.0 is disclosed in JP-A-3-
Japanese Patent No. 264520 describes a skin cleansing / detergent composition having a pH adjusted to 3 to 6 by containing a buffer solution.

However, the above-mentioned JP-A-61-8531
No. 1, JP-A-2-152920, JP-A No. 4-152920
99717, JP-A-4-53531, JP-A-64-38018 and JP-A-3-264520.
The composition described in Japanese Patent Publication is not sufficient as a composition for cleaning the anus around the anus, and further improvement has been desired.

Further, when the cleaning agent is used for cleaning the baby's anus and its surroundings by impregnating a cloth-like material with the cleaning agent, a cleaning agent containing an oil component causes a sticky feeling and the like.
It was something I didn't like to feel. Furthermore, a wiping agent having no pH buffering ability cannot be expected to have an antibacterial action on the skin with a pH buffering effect that does not irritate the skin, and the antibacterial agent cannot be used at the optimum pH.

Therefore, an object of the present invention is to fully exert the effect of an antibacterial agent, to prevent germs from multiplying during storage, and to clean the anus and its surroundings hygienically when the anus and its surroundings are wiped. An object of the present invention is to provide a water-based anal anus cleansing composition which can be kept and does not cause skin roughness or allergies. Further, an object of the present invention is to prevent bacteria from multiplying during storage, and when the anus and its surroundings are wiped, it is possible to keep the anus and its surroundings hygienic, and cause rough skin and allergies. It is to provide a cleansing material around the anus that does not exist.

[0010]

Means for Solving the Problems As a result of intensive investigations, the present inventors have adjusted the pH of a composition for cleaning around the anus around the anus containing an antibacterial agent to a specific range, It was found that the above object can be achieved by adjusting the pH buffering capacity of the composition for use in a specific range.

The present invention has been made on the basis of the above findings, and is a composition for cleaning the anus around the anus containing an antibacterial agent and a pH buffer solution in an amount for adjusting the pH to 4.0 to 6.0. Therefore, a 10-fold diluted solution 30 of the water-based anal anus cleaning composition
Amount of 1/100 normal sodium hydroxide aqueous solution necessary to raise pH of 1.0 by 1.0 ml (hereinafter referred to as "pH buffering capacity" in the present specification, "10 Amount of 1 / 100N sodium hydroxide aqueous solution necessary to raise pH of 30 ml of double-diluted solution 1.0 "
It means that the water content around the anus is 2 to 10 ml.

The present invention also provides a material for cleaning the anus around the anus prepared by impregnating a cloth-like material with the above-described composition for cleaning the area around the anus.

[0013]

BEST MODE FOR CARRYING OUT THE INVENTION First, the water-based anal anus cleansing composition of the present invention will be described in detail. The composition for cleaning around the anus of the present invention has an antibacterial agent and a pH of 4.3 to 5.5.
The pH buffer solution is contained in an amount of 2 to 10 ml, and water is the main component other than the antibacterial agent and the pH buffer solution.

The antibacterial agent used in the present invention is not particularly limited as long as it is used for antibacterial skin, and examples thereof include benzethonium chloride, benzalkonium chloride, cetylpyridinium chloride, chlorhexidine hydrochloride, chlorhexidine gluconate, Triclocarban,
Examples thereof include triclosan, halocarban, and paraoxybenzoic acid ester. These antibacterial agents may be used alone or in combination of two or more.

The content of the above-mentioned antibacterial agent is preferably 0.001 to 0.4% by weight, more preferably 0.1 to 0.22% by weight in the whole composition. When the content of the antibacterial agent exceeds 0.4% by weight, the skin is strongly irritated, which may cause skin roughness and allergies. Further, if it is less than 0.001% by weight, general live bacteria and mold may be propagated.

The pH buffer solution used in the present invention is not particularly limited as long as it can adjust the pH of the water-based composition for cleaning the anus around the anus to a specific range.
For example, a buffer solution containing succinic acid, citric acid, lactic acid, acetic acid or phosphoric acid, or a salt thereof can be mentioned. The pH buffer solution may be a mixture of the acid and a salt thereof, or a mixture of the acid and an inorganic salt such as disodium phosphate. It is not limited to these as long as the pH of the composition for use can be adjusted within a specific range. As the above pH buffer, it is preferable to use a buffer containing succinic acid, citric acid, lactic acid, acetic acid, or a salt thereof from the viewpoint of skin irritation.

The amount of the above-mentioned pH buffer compounded is an amount for adjusting the pH of the water-based anal anus cleansing composition of the present invention to 4.0 to 6.0, preferably 4.3 to 5. The amount is adjusted to 5. In the present invention, as the above pH buffer, a liquid pH buffer prepared in advance can be added to the water-based anal anus cleansing composition so that the pH falls within the above range. The compounds that make up the pH buffer may be mixed directly into the aqueous perianal cleansing composition.

Therefore, the composition for cleaning the anus around the anus of the present invention contains the above pH buffer solution to have a pH of 4.0 to 6.0, preferably 4.3 to 5.5. It is adjusted and has a pH buffering capacity of 2 to 10 ml, preferably 5
It is adjusted to ~ 8 ml. When the pH and pH buffering ability of the water-based anal anus cleansing composition are within the above range,
During storage of the water-based anal peripheral cleaning composition, no germs propagate in the water-based anal perianal cleaning composition, and the periphery of the anus is cleaned using the water-based anal perianal cleaning composition. Does not cause skin irritation when wiped. When the pH is less than 4.0 and the pH buffering capacity exceeds 20 ml, the skin irritation problem occurs, and when the pH is more than 5.5 and the pH buffering capacity is less than 2 ml, the skin irritation problem similarly occurs.

The composition for cleaning around the anus of the present invention is a composition prepared by mixing and dissolving the above antibacterial agent and the above pH buffer solution in water. The water is not particularly limited, and purified water, distilled water, tap water, etc. can be used.

If desired, additives such as humectants such as propylene glycol, 1,3-butylene glycol and glycerin can be added to the water-based anal anus cleansing composition of the present invention. These additives can be added preferably in an amount of 0 to 10% by weight, more preferably 2 to 5% by weight, based on the total amount of the composition for cleaning the anus around the anus.

The composition for cleaning the anus around the anus of the present invention can be used as a cleaning material around the anus by impregnating it with a cloth-like material as described later. Further, it is also possible to apply the water-based anal anus cleansing composition of the present invention to toilet paper, tissue paper or the like to clean the anus and its surroundings.
The water-based composition for cleaning the anus around the anus of the present invention may be applied to the anus and its surroundings, and then wiped off with a toilet paper, a tissue paper or the like. When the water-based composition for cleaning the periphery of the anus of the present invention is applied to toilet paper or the like or when applied to the anus and its periphery, it can be used by filling it in a sprayer and spraying. In this case, it can be used by filling it into a conventionally known atomizer, but it is particularly preferable to use it as an aerosol preparation filled in an aerosol container or as a spray using a pressure-accumulation pump bottle.

The composition of the present invention for cleaning around the anus includes:
Since the antibacterial agent is contained, the anus and its surroundings can be kept hygienic when cleaning the anus and its surroundings. Further, since the content of the antibacterial agent can be made smaller than that of the conventional water-based anal anus cleansing composition, it does not cause irritation to the skin and does not cause skin irritation or allergies. Furthermore, the composition for cleaning around an anus of the present invention is p
Since H is adjusted to be weakly acidic, when the anus and its surroundings are wiped off, the growth of bacteria in the anus and its surroundings is suppressed, and resistance to bacteria can be imparted to the wiped skin. .

Next, the cleaning material around the anus of the present invention will be described. The cleaning material around the anus according to the present invention is obtained by impregnating a cloth-like material with the above-described composition for cleaning around the anus according to the present invention.

As the cloth-like material used for the cleaning material around the anus of the present invention, either woven cloth or non-woven cloth can be used. Examples of the woven fabric include cotton gauze. As the above-mentioned non-woven fabric, one having flexibility and exhibiting a cloth-like feel is used, and is composed of, for example, natural fibers such as cellulose, regenerated fibers such as rayon and synthetic fibers such as polyethylene, polypropylene and polyethylene terephthalate. There are things that have flexibility,
The material is not limited to these as long as it has a cloth-like feel. The above fibers may be used alone or in combination of two or more.

Thus, the cleaning material around the anus of the present invention is obtained by impregnating the above cloth-like material with the above-described composition for cleaning around the anus of the present invention. The impregnation amount of the water-based composition for cleaning the anus around the anus of the present invention in the cloth for cleaning anus in the vicinity of the anus of the present invention is preferably 10 per 100 parts by weight of the cloth-like material.
0 to 300 parts by weight, more preferably 200 to 26
0 parts by weight. When the impregnation amount exceeds 300 parts by weight, the wiping performance deteriorates, and when it is less than 100 parts by weight, dissatisfaction during use occurs due to lack of wet feeling.

Since the anus-cleaning material of the present invention is impregnated with the water-based composition for cleaning the anus of the present invention, it is possible to suppress propagation of various bacteria during storage. Further, when the anus and its surroundings are wiped using the perianal cleaning material of the present invention, the anus and its surroundings are sanitized by the antibacterial agent contained in the water-based anal anal cleaning composition of the present invention. It can be maintained, and the content of the antibacterial agent is small and the irritation to the skin is small, so that it does not cause skin irritation or allergies. Further, since the pH of the water-based composition for cleaning the anus around the anus impregnated in the material for cleaning the anus around the anus of the present invention is maintained at a weak acidity, the growth of various bacteria in the anus and its surroundings is suppressed.

The perianal cleansing material of the present invention uses a cloth-like material, and since the amount of the antibacterial agent contained in the water-based anal perianal cleansing composition is small and irritation to the skin is small, excretion should be performed by myself. It is suitable as a cleaning material around the anus for cleaning the anus of infants and their surroundings who cannot do it themselves.

[0028]

EXAMPLES The present invention will be described more specifically with reference to the following examples, but the present invention is not limited to the following examples. In addition, in this example, unless otherwise indicated, a part represents a weight part.

Example 1 The following formulations were mixed to obtain a water-based anal anus cleaning composition. Benzethonium chloride 0.030 parts Propylene glycol 3.000 parts 1,3-butylene glycol 2.000 parts Ethylparaben 0.090 parts Propylparaben 0.015 parts Succinic acid 0.300 parts Disodium phosphate 0.280 parts Purified water 94.285 parts The pH of the water-based anal anus cleansing composition having the above composition
Was 4.54. In addition, 6.92 ml of 1/100 normal sodium hydroxide aqueous solution was added to 30 ml of a 10-fold diluted solution of this water-based anal anus cleansing composition.
H was 5.54.

Regarding the above-mentioned water-based anal anus cleansing composition,
The evaluation was performed according to the following [Evaluation Criteria for Aqueous Anus Cleansing Composition].

[Evaluation Criteria for Aqueous Anus Cleansing Composition]
The water-based anal anus cleansing composition was applied to the shaved guinea pig skin once a day for 5 days, and the skin condition was observed for 5 days. As a result, no problem such as skin irritation was observed.

Comparative Example 1 The procedure of Example 1 was repeated except that the amounts of succinic acid and disodium phosphate were changed.
A composition for cleaning around the anus in the water system was obtained. 30 ml of a 10-fold diluted solution of the water-based anus-cleaning composition thus obtained
2.0 ml of 1/100 normal sodium hydroxide solution
Upon addition, the pH rose above 1.0. When the composition for cleaning around the anus around the anus thus obtained was evaluated in the same manner as in Example 1, there was skin irritation such as reddening of the skin.

[0033]

EFFECTS OF THE INVENTION The water-based anal anus cleansing composition of the present invention comprises:
Miscellaneous bacteria do not propagate during storage, and when the anus and its surroundings are wiped, the anus and its surroundings can be kept hygienic and there is no rough skin or allergies. In addition, the cleaning material around the anus of the present invention does not cause miscellaneous bacteria to proliferate during storage, and when cleaning the anus and its periphery, the anus and its periphery can be kept hygienic,
It does not cause skin irritation or allergies.

Claims (5)

[Claims] 1. A water-based anal anus cleansing composition comprising an antibacterial agent and a pH buffer solution in an amount for adjusting pH to 4.0 to 6.0. The water-based anal anus cleansing composition is characterized in that the amount of 1/100 normal sodium hydroxide aqueous solution required to raise the pH of 30 ml of the 10-fold diluted solution of 1 is 2 to 10 ml. 2. The water-based anal anus cleansing composition according to claim 1, wherein the pH buffer solution is a buffer solution containing succinic acid, citric acid, lactic acid, acetic acid or salts thereof. 3. The content of the antibacterial agent is 0.001 to 0.
The water-based anal anus cleansing composition according to claim 1 or 2, which is 4% by weight. 4. A cleaning material around an anus prepared by impregnating a cloth-like material with the water-based composition for cleaning around an anus according to claim 1. 5. The impregnated amount of the water-based anal anus cleansing composition is 100 to 300 with respect to 100 parts by weight of the cloth-like material.
The cleaning material around the anus according to claim 4, which is a weight part.