JPH09315950A - Thickening gelation agent and cosmetic containing the same - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a thickening gelation agent containing a specific branched aliphatic polyglycoside, having an excellent thickening gelation ability and persistently giving a good moisture-retaining property and a use touch, and to obtain a cosmetic containing the same. SOLUTION: This thickening gelation agent contains a branched aliphatic polyglycoside of the formula Gn-O-R Gn is a residue obtained by removing the hydroxyl group of the glycoside from the dehydrative condensation product [have a polymerization degree of (n)]} of a monosaccharide G. Therein, a breached aliphatic monoglycoside having a polymerization degree (n) of 1 is contained in an amount of >=5wt.% based on the whole amount of the branched aliphatic polyglycosides, and the bracbched aliphatic polyglycosides have an average polymerization degree of 1.8-2.1. The gelation ability and the using touch of the thickening gelation agent depend on the contents and the average polymerization degree of the branched aliphatic monoglycosides. The addition of the thickening gelation agent to the cosmetic gives a high moisture-retaining property and a persistent moist and stiff touch.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to an improvement in the composition of a thickening gelling agent, particularly a thickening gelling agent containing a branched aliphatic polyglycoside.

[0002]

2. Description of the Related Art Various aqueous thickening gelling agents are used in the fields of pharmaceuticals, cosmetics and the like to maintain their dosage forms. For example, as the organic compounds, polysaccharides, natural polymers such as casein, synthetic polymers such as polyoxyethylene and acrylic acid polymers, and as the inorganic compounds, various clay minerals such as montmorillonite are used. It is appropriately selected and used according to the effect.

When such a thickening gelling agent is used in medicines and cosmetics, it is required to have high safety for use on the human body, and at the same time, when it is used externally on the skin. Requires a good usability. Therefore, a thickening gelling agent is required to have both high safety, favorable usability, and good thickening gelling ability, but conventional thickening gelling agents sufficiently satisfy these three factors. I couldn't do it.

[0004] For example, a polymer type is relatively safe and exhibits a good thickening and gelling ability when added in a small amount.
There is a slimy feeling peculiar to polymers when used on the skin,
It was an unpleasant feeling. Further, the clay mineral has a high thixotropic property and has a refreshing and pleasant feeling to use, but syneresis is likely to occur and the gel is unstable.
From these problems, it has been desired to develop a thickening gelling agent that can satisfy all of safety, usability and thickening gelling ability.

In recent years, research on branched aliphatic polyglycosides has been advanced as a thickening gelling agent for solving such problems (Japanese Patent Laid-Open No. 4-76082). This branched aliphatic polyglycoside is an excellent substance which is excellent in stability and safety, and can exert a thickening gel capability even at a low concentration. However, even if the branched aliphatic polyglycoside has the same type of fatty chain and sugar, and the average degree of polymerization of sugar, its gelling ability and feeling of use are not constant, and when it is actually added to the product as a thickening gelling agent, There is a problem in that the amount to be blended cannot be specified and it is difficult to use.

The present invention has been made in view of the above problems of the prior art, and its purpose is to clarify the relationship between the structure and properties of a thickening gelling agent containing a branched aliphatic polyglycoside. Another object of the present invention is to provide a thickening gelling agent that constantly obtains an excellent gelling ability and a feeling of use, and a cosmetic containing the same.

[0007]

Means for Solving the Problems As a result of intensive investigations by the present inventors in order to achieve the above-mentioned object, the thickening gelling agent containing a branched aliphatic polyglycoside has a gelling ability and a feeling of use. The present invention has been completed by finding that it is influenced by the content of branched aliphatic monoglycoside and the average degree of polymerization of branched aliphatic polyglycoside.

That is, according to the present invention, in a thickening gelling agent containing a branched aliphatic polyglycoside represented by the general formula 2, a branched aliphatic monoglycoside having a degree of polymerization n of 1 is added to the total amount of the branched aliphatic polyglycoside. And 5% by weight or more, and the average degree of polymerization of the branched aliphatic polyglycoside as a whole is in the range of 1.8 to 2.1. It concerns cosmetics.

[0009]

Embedded image In the formula, Gn means a residue obtained by removing a glycosidic hydroxyl group from a monosaccharide G dehydrated and condensed at a degree of polymerization of n.
n is an integer of 1 or more. Further, R means a branched fatty chain having a glycoside bond with Gn and having a total carbon number of 8 to 32. )

[0010]

BEST MODE FOR CARRYING OUT THE INVENTION Embodiments of the present invention will be described in detail below. In the general formula 2, Gn is a monosaccharide G
Represents a residue obtained by removing a glycosidic hydroxyl group from a product dehydrated and condensed at a polymerization degree of n. Specific examples of the monosaccharide G include monosaccharides such as glucose, galactose, xylose, fructose, altrose, talose, mannose, arabinose, idose, lyxose, ribose and allose, and mixtures thereof. The degree of polymerization n is an integer of 1 or more. When n is 1, the monosaccharide is not dehydrated and condensed, and only one monosaccharide is R-glycoside-bonded.

Next, R is a branched fatty chain linked to Gn by a glycosidic bond and has a total carbon number of 8 to 32. Specific examples of the branched chain include, for example, methyl group, ethyl group, propyl group, isopropyl group, butyl group, pentyl group, hexyl group, heptyl group, octyl group, nonyl group,
Decyl group, undecyl group, dodecyl group, tridecyl group,
Examples thereof include a tetradecyl group, a heptadecyl group, a hexadecyl group, a heptadecyl group, and further higher fatty chains. The position and number of such branched chains are not particularly limited. Specific examples of R include 2-decyltetradecyl group, 2-tetradecyloctadecyl group, isostearyl group, 2,7-dimethylhexadecyl group, tetrahydrageranyl group, and 2,7-dimethyloctadecyl group. . R is a hydrophobic group, and the total number of carbon atoms is preferably 8 to 32 from the viewpoint of balance and industrial property.

The branched aliphatic polyglycoside according to the present invention can be obtained by a dehydration condensation reaction of a branched aliphatic alcohol and a sugar, a method using an acid catalyst for saccharide modification described in JP-A-63-84637, and generally glycosyl. The compound can be synthesized by the reaction used for the compound (König-Knol reaction, Helferreich method, other ether exchange method, etc.).

During the steps of these synthetic reactions, sugars used as raw materials are polymerized with each other, and thus the obtained branched aliphatic polyglycoside is usually obtained as a mixture having different degrees of polymerization of sugars and different bonding positions of sugars. In the present invention, even with such a mixture, the content of the branched aliphatic monoglycoside is 5% by weight based on the total amount of the branched aliphatic polyglycoside.
When the average degree of polymerization of the branched aliphatic polyglycoside is in the range of 1.8 to 2.1, the branched aliphatic polyglycoside can be used as it is. Of course, the mixture is appropriately purified to obtain a highly pure branched aliphatic polyglycoside, and these are prepared so as to have the branched aliphatic monoglycoside content and the average degree of polymerization of the branched aliphatic polyglycoside, which are the features of the present invention. You may fix it and use it.

The thickening gelling agent of the present invention is oily or solid at room temperature, and exhibits thickening gelling ability at a low concentration.
When blended in a cosmetic composition, it has a high moisturizing property and gives a moist and soft feeling during use, and the moist feeling is continuously obtained. Moreover, irritation is not particularly recognized. In addition, even at a low temperature, the rate of dissolution in water is fast, the system can be rapidly dissolved to thicken the system, and the viscosity-stabilized gelled system has good viscosity stability. Further, the branched aliphatic polyglycoside of the present invention is stable without being decomposed even in acid or alkali, so that it does not reduce the amount of acid or alkali in the system.

The branched aliphatic polyglycoside of the present invention can be blended in various cosmetics for hair such as shampoo, rinse, treatment, hair styling agent, hair dye, color rinse, etc., in addition to skin cosmetics. In particular, when the thickening gelling agent of the present invention is added to a hair dye or a color rinse, the hair dye does not drip during the hair dyeing treatment, and the extensibility and the coatability are good,
Further, it is possible to obtain a hair dye or color rinse which has no uneven dyeing on the finish and also has good dyeing properties and wash resistance.

Further, lower alcohols such as ethanol and isopropanol are often blended in the hair dye composition, and the conventional thickening gelling agent may reduce the thickening effect in such a system. However, in the thickening gelling agent according to the present invention, even when used in such a system, the thickening effect does not decrease, and a thickening gel can be formed with a small amount. Since the thickening gelling agent of the present invention is excellent in safety and stability, it can be applied to medicines.

The blending amount of the thickening gelling agent according to the present invention to be blended in the cosmetic of the present invention is not particularly limited as long as the effects of the present invention can be obtained, and the blending amount is appropriately adjusted before use. be able to. Further, in the cosmetic of the present invention, in addition to the branched aliphatic polyglycoside as the thickening gelling agent, other components usually used in cosmetics can be appropriately blended unless the effects of the present invention are impaired.

For example, liquid paraffin, squalane, petrolatum, cetyl alcohol, isostearyl alcohol, 2-ethylhexyl alcohol, cetyl-2-octyldodecyl alcohol 2-ethylhexanoate, glyceryl triisostearate, macadamian nut oil, lanolin, etc. Various hydrocarbons, oils and fats, oil components such as waxes, silicones, other surfactants, thickeners, neutralizers,
Preservative, bactericide, antioxidant, powder component, pigment, fragrance,
Examples thereof include, but are not limited to, ultraviolet absorbers, medicinal agents, sequestering agents, pH adjusting agents and the like.

Known components usually used in hair dyes, such as oxidation dyes, acid dyes, various alcohols,
Organic solvents, pH adjusters, inorganic acids, humectants, oily ingredients, sequestering agents, preservatives, cationic polymers, pH adjusters, fragrances, drugs, water, other amphiphilic substances and surfactants , Thickeners, protein hydrolysates and their tetrachlorides,
Antioxidants, stabilizers, alkaline agents, oxidizing agents and the like can also be added.

The thickening gelling agent of the present invention is a thickening gelling agent containing a branched aliphatic polyglycoside represented by the above Chemical Formula 2, in particular, a branched aliphatic monoglycoside having a degree of polymerization n of 1 is branched. It is characterized in that it is contained in an amount of 5% by weight or more based on the total amount of the aliphatic polyglycoside, and that the average degree of polymerization of the branched aliphatic polyglycoside is in the range of 1.8 to 2.1. The content of the branched aliphatic monoglycoside and the average degree of polymerization of the branched aliphatic polyglycoside have a great influence on the effect of the present invention.

For example, even if the content of the branched aliphatic monoglycoside is 5% by weight or more, when the average degree of polymerization of the branched aliphatic polyglycoside is out of the range of 1.8 to 2.1, sufficient gelation occurs. Noh is not demonstrated. Even if the average degree of polymerization of the branched aliphatic polyglycoside is in the range of 1.8 to 2.1, the dissolution rate is slow when the content of the branched aliphatic monoglycoside is less than 5% by weight, and The excellent moisturizing properties, the feeling of use and their durability as obtained by the present invention cannot be obtained. Therefore, in the present invention, the content of the branched aliphatic monoglycoside and the average degree of polymerization of the branched aliphatic polyglycoside are closely related to each other, and the excellent effects of the present invention are exhibited.

The embodiment of the present invention will be described in more detail below with reference to the case of the isostearyl polyglucoside in which R is an isostearyl group and G is glucose in the above Chemical Formula 2. First, a method for producing isostearyl polyglucoside will be described.

Production Example 1 Isostearyl polyglucoside Isostearyl alcohol 10.05 g (378 mmol)
Glucose (40.5 g, 225 mmol) and paratoluenesulfonic acid (0.19 g, 1 mmol) were added thereto, and the mixture was reacted for 8 hours under reduced pressure while introducing nitrogen while stirring. The reaction product was cooled to room temperature, and purified water, methanol, and ethyl acetate were added to the reaction system for partition. The aqueous layer was concentrated to give isostearyl polyglucoside. The average degree of polymerization of glucose in the obtained isostearyl polyglucoside was 25 mg of isostearyl polyglucoside, 0.5 ml of trimethylchlorosilane,
N, 0- (bistrimethylsilyl) acetamide 0.5m
1, 0.5 ml of N-trimethylsilylimidazole was added, and TMS was formed on a hot water bath at 80 ° C. for 30 minutes, and gas chromatography (column packing; manufactured by Nippon Chromato Kogyo Co., Ltd., Diasolid ZT inner diameter smm, length 50 c).
m, heating rate 100 to 340 ° C., 10 ° C./min, carrier gas and flow rate: nitrogen, 50 ml / min, detector:
The area intensity of the peak was calculated by FID),
The average degree of polymerization of glucose was 2.0. The obtained isostearyl polyglucoside was a mixture of isostearyl polyglucosides having various degrees of polymerization of glucose, and the composition ratio was as shown in Table 1.

[0024]

[Table 1] ──────────────────────────────────── Isostearyl polyglucoside Degree of polymerization n Composition ratio ( mol%) ──────────────────────────────────── Isostearyl monoglucoside 1 46 Isostearyl diglucoside 2 29 Isostearyl triglucoside 3 11 Isostearyl tetraglucoside 4 6 Isostearyl pentaglucoside 5 4 Isostearyl hexaglucoside 6 2 Isostearyl heptaglucoside 7 1 ──────────────────── ─────────────────

Production Example 2 Isostearyl monoglucoside
(G = glucose, n = 1) isostearyl alcohol 10.05 g (378 mmol)
Pentaacetyl glucoside 2g, molybdophosphoric acid 10
mg and toluene 20 ml were added, and the mixture was heated and stirred under a reduced pressure of 20 mmHg for 30 minutes, then air-cooled, and toluene,
Partitioned with water. The obtained toluene phase was concentrated under reduced pressure,
The obtained syrup was purified by a silica gel chromatogram method (Wako Gel C-200, hexane / ethyl acetate) to obtain an acetylated product of isostearyl monoglucoside. The resulting acetylated product was dissolved in methanol, deacetylated with sodium methylate, and then neutralized with a resin.
After the resin was filtered off, the obtained filtrate was concentrated to obtain the desired isostearyl monoglucoside.

Production Example 3 Isostearyl maltotrioxy
10.05 g (378 mmol) of isostearyl alcohol (G = glucose, n = 3 )
2 g of acetyl maltotrise and 10 m of molybdophosphoric acid
g and 20 ml of toluene were added, and the mixture was heated and stirred for 30 minutes at 90 ° C. under a reduced pressure of 20 mmHg, then cooled with air, and partitioned with toluene and water. The obtained toluene phase was concentrated under reduced pressure, and the obtained syrup was purified by a silica gel chromatogram method (Wakogel C-200, hexane / ethyl acetate) to obtain an acetylated product of isostearyl maltotrioside. The resulting acetylated product was dissolved in methanol, deacetylated with sodium methylate, and then neutralized with a resin. After the resin was filtered off, the obtained filtrate was concentrated to obtain the desired isostearyl maltotrioside.

Production Example 4 Isostearyl maltoside (G
= Glucose, n = 2) 10.05 g (378 mmol) of isostearyl alcohol
Acetyl maltose 2 g, molybdophosphoric acid 10 mg,
After adding 20 ml of toluene and heating and stirring under reduced pressure of 90 ° C. and 20 mmHg for 30 minutes, the mixture was air-cooled and partitioned with toluene and water. The obtained toluene phase was concentrated under reduced pressure, and the obtained syrup was purified by a silica gel chromatogram method (Wakogel C-200, hexane / ethyl acetate) to obtain an acetylated product of isostearyl maltoside. The resulting acetylated product was dissolved in methanol, deacetylated with sodium methylate, and then neutralized with a resin. After the resin was filtered off, the obtained filtrate was concentrated to obtain the desired isostearyl maltoside.

Test Example 1 Gelation Ability Isostearyl polyglucosides having various average degrees of polymerization were prepared, 5 g of this isostearyl polyglucoside was added to 100 ml of water and dissolved, and their viscosities were compared.
Adjustment of the average degree of polymerization of isostearyl polyglucoside,
It was carried out by adding the isostearyl monoglucoside obtained in Production Example 2 or the isostearyl maltotrioside obtained in Production Example 3 to the isostearyl polyglucoside having an average degree of polymerization of 2 prepared in Production Example 1. The viscosity is measured by an E-type viscometer (manufactured by Tokimec Co., VISCO
NIC ED type) and the temperature was 25 ° C. and the corn rotor was 0.5 rpm.

FIG. 1 shows the results. As can be seen from FIG. 1, when the average degree of polymerization is in the range of 1.8 to 2.1, the thickening gelling ability is exhibited, and the system becomes a transparent viscous liquid to gel. If it comes off, the system cannot be gelled. Therefore, it is understood that the average degree of polymerization of the branched aliphatic polyglycoside in the thickening gelling agent of the present invention needs to be in the range of 1.8 to 2.1.

Test Example 2 Dissolution Rate Next, the average degree of polymerization of isostearyl polyglucoside was 2
The rate of dissolution in water was examined when the content of isostearyl monoglucoside contained in isostearyl polyglucoside was changed by fixing the solution to water. The method for preparing the isostearyl polyglucoside having the average degree of polymerization of 2 used in the test was the same as the isostearyl monoglucoside obtained in Production Example 2 and the production example 3 in addition to the isostearyl maltoside obtained in Production Example 4. This was done by adding an equal mixture of isostearyl maltotrioside. The dissolution rate is 5g of isostearyl polyglucoside, which is the sample.
Was added to water to make 100 ml in total, and the time required for complete dissolution was measured under the conditions of a stirring speed of 100 revolutions / minute and a temperature of 25 ° C. for comparison. The complete dissolution was determined by visual observation.

Table 2 shows the dissolution rate of each sample solution and the properties after dissolution.

[Table 2] ──────────────────────────────────── Isostearyl monoglycolide content (% by weight) ) 0 1 3 5 10 ──────────────────────────────────── Dissolution time (min) 120 60 30 5.5 5 Properties after dissolution Gel-like gel-like gel-like gel-like gel-like ───────────────────────────────── ──── As can be seen from Table 2, all sample solutions became transparent gels after dissolution, but were dissolved depending on the content of isostearyl monoglucoside, even though the average degree of polymerization was 2. A significant difference in speed was observed. When the content of isostearyl monoglucoside is 5% by weight or more, the dissolution rate is faster than when it is less than 5% by weight, and when the isostearyl monoglucoside content is 0 (isostearyl maltoside content 100% In the case of), the dissolution rate was extremely slow.

Test Example 3 Moisture Retaining Property and Feeling in Use Using the sample of Test Example 2 above, further tests were carried out as to the moisturizing property and feel in use as follows. [Humidity test] 10 μl each of the sample solution or ion-exchanged water (control) prepared in Test Example 2 was placed on a glass cell and left in a thermostat at 25 ° C. for 8 minutes. The glass cell was weighed before and after being left in the constant temperature bath, the water evaporation amount was obtained, and the water evaporation coefficient K was calculated. The relative value of each sample solution was calculated with the reciprocal 1 / KH ₂ O of the water evaporation coefficient of ion-exchanged water (control) as 1, and this was evaluated as the moisturizing effect value. The larger this relative value is, the higher the moisturizing property is.

[Usage Test] Using the various isostearyl polyglucosides prepared in Test Example 1 as samples, jelly-like lotion was prepared according to the following formulation, and a usage test was conducted by 10 panelists. <Prescription> Ethanol 10.0 wt% Ethylparaben 0.1 Isostearyl polyglucoside 2.5 Perfume 0.2 Purified water Residual

Feeling of use immediately after application to the skin and after application 6
A questionnaire was sent to the panelists regarding the feeling of use of time and evaluated according to the following criteria. Immediately after use ○: When 8 or more respondents answered that they are moisturized and moisturized △: 4 to 4 when they are moisturized and moisturized
In the case of 7 people ×… When 3 people or less responded that they were moist with a feeling of use. Evaluation criteria after 6 hours ○ When 8 or more people answered that they still had a moist feeling △… Moist feeling If 4 to 7 respondents say that there is still a mark .... If there are 3 or fewer respondents that a moist feeling remains.

The results are shown in Table 3.

[Table 3] ──────────────────────────────────── Isostearyl monoglycolide content (% by weight) ) 0 1 3 5 10 ──────────────────────────────────── Moisturizing effect 1.1 1.2 1.2 1.5 1.7 Use Immediate usage feeling ○ ○ ○ ○ ○ Usage feeling after 6 hours △ △ △ ○ ○ ─────────────────────────────── ──────

As can be seen from Table 3, when the content of isostearyl monoglucoside was 5% by weight or more based on the total amount of isostearyl polyglucoside, it was revealed that the evaporation rate of water was slow and the moisture retention was high. . When it was applied to the skin, the moist feeling was maintained not only immediately after use but also after 6 hours, and excellent moisturizing properties were exhibited. On the other hand, when the content of isostearyl monoglucoside is less than 5% by weight, the feeling immediately after use is thick and there is also a moist feeling, but no moist feeling is felt after 6 hours, and the content rate is 5% by weight. The feeling of use was inferior to that in the case of more than%. It is considered that this is because the evaporation rate of water is high when the content of monoglucoside is less than 5% by weight.

As a comparative example, the same test was conducted for the case where the content of monoglucoside was 100% (monoglucoside alone). In this case, however, the average degree of polymerization was 1, so that the system was not gel-like. In addition, the moisturizing effect and the feeling of use were inferior to those of the present invention.

From the above, in the thickening gelling agent of the present invention, the content of the branched aliphatic monoglycoside is 5% by weight or more based on the total amount of the branched aliphatic polyglycoside, and the branched aliphatic polyglycoside is Has an average degree of polymerization of 1.8 to
It is important to exist in the range of 2.1, and it is understood that excellent gelling ability is obtained, and at the same time, excellent moisturizing property, usability and durability thereof are exhibited.

[0039]

[Examples] The production examples of branched aliphatic polyglycoside which is the thickening gelling agent according to the present invention and the blending examples of cosmetics containing the same are shown below, but the present invention is not limited thereto. . The blending amount is represented by wt% unless otherwise specified. Production Example 5 Isomyristyl polyglucoside Isomyristyl alcohol 7.97 g (378 mmol) was added with glucose 40.5 g (225 mmol) and paratoluenesulfonic acid 0.19 g (1 mmol), and nitrogen was introduced under reduced pressure for 8 hours while stirring. Reacted The reaction product was cooled to room temperature, and purified water, a small amount of methanol and hexane were added to the reaction system for partitioning. The aqueous layer was concentrated, and the obtained syrup was washed with acetone to obtain isomyristyl polyglucoside. When the average degree of polymerization of glucose in the obtained isomyristyl polyglucoside and the content rate of isomyristyl monoglucoside relative to the total amount of isomyristyl polyglucoside were examined in the same manner as in Production Example 1, the average degree of polymerization was 1.
8. The content of isomyristyl monoglucoside was 50%.

Formulation Example 1 Jelly-like lotion (1) Ethanol 10.0 wt% (2) Hyaluronic acid 5.0 (3) Ethylparaben 0.1 (4) Isostearyl polyglucoside 2.5 (Average degree of polymerization 2. 0, content of mono-body 20%) (5) Fragrance 0.2 (6) Purified water Residues (1) to (6) were well mixed and dissolved to obtain a jelly-like lotion. This lotion had an appropriate viscosity, and a moist and good feeling during use was continuously obtained. Further, when stored at 0 ° C., 25 ° C. and 50 ° C., all were stable and no separation or the like occurred.

Formulation Example 2 Nutritive emulsion oil phase part; (1) Beeswax 1.0 wt% (2) Deodorized lanolin 1.0 (3) Jojoba oil 6.0 (4) Cetylisooctanoate 4.0 (5) ) POE (3) 2-octidodecanol 2.0 (6) Ethylparaben 0.2 (7) Butylparaben 0.1 (8) Vaseline 2.0 (9) Fragrance 0.3 Water phase part; (1) Hydroxypropyl cellulose 0.2 wt% (2) Xanthan gum 0.5 (3) Isostearyl polyglucoside 1.0 (Average degree of polymerization 1.8, mono-content 21%) (4) Dipropylene glycol 2.0 (5 ) L-Arginine 0.2 (6) Purified water Residue

The oil phase part and the water phase part are respectively melted by heating,
The aqueous phase was added to the oil phase and the emulsion was cooled to obtain a nutrient emulsion. This emulsion had an appropriate viscosity, and a moist and good feeling during use was continuously obtained. Further, when stored at 0 ° C., 25 ° C. and 50 ° C., all were stable and no separation or the like occurred.

Formulation Example 3 Cream (1) Vaseline 2.0 wt% (2) Stearyl alcohol 1.0 (3) Stearic acid 0.5 (4) Methylpolysiloxane 2.0 (5) Batyl alcohol 1.5 (6) ) Liquid paraffin 5.0 (7) Preservative Suitable (8) Perfume Suitable (9) Isostearyl polyglucoside 2.0 (Average degree of polymerization 2.0, mono-body content 15%) (10) Glycerin 5. 0 (11) Ethanol 7.0 (12) Carboxyvinyl polymer Suitable (13) Ion-exchanged water Residual (14) Potassium hydroxide 0.1

After dissolving (9) to (13) and heating and stirring, (14) is added to form an aqueous phase. (1) to (8) are heated and stirred to form an oil phase. The oil phase was gradually added to the aqueous phase to emulsify and cool to obtain a cream. This cream had an appropriate viscosity, and a moist and good feeling during use was continuously obtained. Further, when stored at 0 ° C., 25 ° C. and 50 ° C., all were stable and no separation or the like occurred.

Formulation Example 4 Emulsion (1) Stearic acid 2.0 wt% (2) Cetyl alcohol 0.8 (3) Squalane 10.0 (4) Vaseline 2.0 (5) Isostearyl polyglucoside 3.0 (average) (Polymerization degree 1.9, Mono-body content 45%) (6) Lanolin 2.0 (7) Acetate α-tocopherol 0.05 (8) Perfume Suitable (9) Propylene glycol 5.0 (10) Triethanolamine 1.0 (11) Carboxyvinyl polymer 0.1 (12) Ion-exchanged water Residual

(1) to (8) are heated and dissolved at 70 to 75 ° C. (oil phase). (9) to (12) are heated and dissolved at 70 to 75 ° C,
While continuing stirring, the oil phase was gradually added to this and emulsified. Furthermore, after processing with an emulsifier, it was cooled to 30 ° C. to obtain an oil-in-water emulsion. This emulsion had an appropriate viscosity, and a moist and good feeling during use was continuously obtained.
Further, when stored at 0 ° C., 25 ° C. and 50 ° C., all were stable and no separation or the like occurred.

Formulation 5 Hair rinse (1) Stearyl trimethyl ammonium chloride 2.0 wt% (2) Liquid paraffin 3.0 (3) Cetanol 1.5 (4) Isomyristyl polyglucoside 3.0 (Average degree of polymerization 2.0 , Mono content 46%) (5) Citric acid suitable (6) Dye suitable (7) Perfume suitable (8) Ion-exchanged water residue

The hair rinse prepared by the conventional method with the above-mentioned formulation had an appropriate viscosity, and had a good moisturizing and good feeling of use, and a moist feeling on the hair after use was obtained. Also, 0
When stored at 0 ° C, 25 ° C and 50 ° C, all were stable and no separation or the like occurred.

Formulation 6 Shampoo (1) Sodium lauryl sulfate 5.0 wt% (2) Alkyldimethylaminoacetic acid betaine 2.0 (3) Coconut oil fatty acid diethanolamide 3.0 (9) Isomyristyl polyglucoside 10.0 ( (Average degree of polymerization: 1.9, content of mono-compound: 50%) (5) EDTA ・ 2 sodium is suitable (6) Fragrance is suitable (7) Ion-exchanged water

The shampoo prepared by the conventional method with the above-mentioned formulation has an appropriate viscosity, has a good and moisturizing and good feeling of use, has no squeaks during washing, and has a moist feeling on the washed hair. . Further, when stored at 0 ° C., 25 ° C. and 50 ° C., all were stable and no separation or the like occurred.

Formulation Example 7 Lipstick (1) Castor oil 45.0 wt% (2) Hexadecyl alcohol 25.0 (3) Lanolin 4.0 (4) Beeswax 4.0 (5) Isostearyl polyglucoside 3.0 ( (Average degree of polymerization 2.0, content of mono-compound 36%) (6) Ozokerite 3.0 (7) Candelilla wax 6.0 (8) Carnauba wax 2.0 (9) Antioxidant Suitable (10) Preservative Appropriate (11) Titanium oxide 2.0 (12) Red No. 202 0.5 (13) Red No. 204 2.5 (14) Red No. 227 AI chelate 2.5 (15) Orange No. 201 0.2 (16) ) Perfume suitable

(1) to (10) are heated and stirred to uniformly mix them. (1
(1) to (15) were added, and the mixture was kneaded with a funnel and uniformly dispersed, and then heated and dissolved again, (16) was added, and after defoaming, the mixture was poured into one direction and rapidly cooled to solidify. The solidified product was taken out of the mold and filled in a container. When applied to the skin, this lipstick has a moisturizing and good feeling when used at 0 ° C, 25 ° C, 50 ° C.
When stored at ℃, all were stable and no separation occurred.

Formulation 8 Base cream (1) Stearic acid 0.9 wt% (2) Stearyl alcohol 1.6 (3) Vaseline 3.0 (4) Methyl polysiloxane 2.4 (5) Liquid paraffin 7.0 ( 6) Batyl alcohol 1.3 (7) Preservative Suitable (8) Perfume Suitable (9) Isostearyl polyglucoside 10.0 (Average degree of polymerization 2.0, Monomer content 41%) (10) Carboxyvinyl Polymer Suitable (11) Glycerin 5.0 (12) Ethanol 7.0 (13) Ion-exchanged water Residual (14) Potassium hydroxide 0.1

(1) to (8) are heated and dissolved at 70 to 75 ° C. (oil phase). (9) to (12) are heated and dissolved at 70 to 75 ° C,
While continuing stirring, the oil phase was gradually added to this and emulsified. Furthermore, after processing with an emulsifier, it was cooled to 30 ° C. to obtain an oil-in-water base cream. This base cream had an appropriate viscosity, and a moist and good feeling for use was continuously obtained. Further, when stored at 0 ° C., 25 ° C. and 50 ° C., all were stable and no separation or the like occurred.

Formulation Example 9 Emulsion foundation (1) 1,3-butylene glycol 4.5 wt% (2) Bentonite 1.1 (3) Isostearyl polygalactoside 1.0 (average degree of polymerization 2.0, mono-body content rate) 39%) (4) Potassium hydroxide 0.1 (5) Vaseline 2.2 (6) Liquid paraffin 11.0 (7) Cetanol 2.5 (8) Monooleyl glyceryl ether 2.5 (9) Isopropyl myristate 2.5 (10) Preservative Suitable (11) Perfume Suitable (12) Titanium oxide 10.0 (13) Ion-exchanged water Residual

(1) to (4) are added to (13) and the mixture is heated and stirred to form an aqueous phase. (5) to (11) are heated and stirred to be dissolved to obtain an oil phase. (12) is added to the aqueous phase, mixed with stirring, and then the oil phase is added and emulsified. This was cooled to room temperature to obtain an emulsified foundation. This emulsified foundation has an appropriate viscosity, has a good feel with a rich body,
When stored at 0 ° C and 50 ° C, both were stable and no separation or the like occurred.

Formulation Example 10 Emulsion foundation (1) 1,3-butylene glycol 5.0 wt% (2) Bentonite 1.0 (3) Isostearyl polygalactoside 2.0 (average degree of polymerization 2.0, content of mono-body) 47%) (4) Potassium hydroxide 0.1 (5) Vaseline 2.0 (6) Liquid paraffin 10.0 (7) Cetanol 2.0 (8) Monooleyl glyceryl ether 2.0 (9) Isopropyl myristate 2.0 (10) Preservative Suitable (11) Perfume Suitable (12) Formulated powder * 20.0 (13) Ion-exchanged water balance * Formulated powder; titanium oxide 8, kaolin 5, talc 6, iron oxide 1

(1) to (4) are added to (13) and the mixture is heated and stirred to form an aqueous phase. (5) to (11) are heated and stirred to be dissolved to obtain an oil phase. (12) is added to the aqueous phase, mixed with stirring, and then the oil phase is added and emulsified. This was cooled to room temperature to obtain an emulsified foundation. This emulsified foundation had an appropriate viscosity, and a rich, moist and good feeling during use was continuously obtained. Further, when stored at 0 ° C., 25 ° C. and 50 ° C., all were stable and no separation or the like occurred.

Blending Example 11 Kneading toothpaste (1) Magnesium carbonate 4.5 wt% (2) Glycerin 1.1 (3) Isostearyl polygalactoside 1.0 (average degree of polymerization 2.0, mono-content 25%) ( 4) Sweetener 0.1 (5) Preservative Suitable (6) Flavor Suitable (7) Dye 2.5 (8) Ion-exchanged water Residue

The paste toothpaste produced by the usual method with the above formulation was stable at 0 ° C., 25 ° C. and 50 ° C., and was stable and did not separate.

Formulation Example 12 Shampoo (1) Ethylene glycol fatty acid ester 2.0 wt% (2) Lauryl sulfobetaine 10.0 (3) Isomyristyl polygalactoside 10.0 (average degree of polymerization 2.0, mono-content 42 %) (4) Diethanolamide laurate 5.0 (5) Propylene glycol 2.0 (6) Suitable for fragrance (7) Suitable for dye (8) Residual ion-exchanged water

The shampoo produced by the conventional method with the above-mentioned formulation had an appropriate viscosity, had a good and moisturizing and good feeling of use, no creaking during washing, and a moist feeling on the hair after washing. . Further, when stored at 0 ° C., 25 ° C. and 50 ° C., all were stable and no separation or the like occurred.

Formulation 13 Body soap (1) Polyoxyethylene (3) lauryl ether sodium sulfate 15.0 wt% (2) Polyoxyethylene (3) lauryl ether sodium sulfate 2.0 (3) Isomyristyl polygalactoside 5. 0 (Average degree of polymerization: 2.0, Mono-content: 21%) (4) Laurylamidopropyl betaine 5.0 (5) Ethanol 2.0 (6) Perfume suitable (7) Dye suitable (8) Ion exchange Water residue

The body soap produced by the conventional method with the above-mentioned formulation had an appropriate viscosity, had a rich and moisturizing good use feeling, and the skin after washing was moist and not moisturized. Further, when stored at 0 ° C., 25 ° C. and 50 ° C., all were stable and no separation or the like occurred.

Formulation Example 14 Body soap (1) Glycerin 5.0 wt% (2) Sodium lauryl sulfosuccinate 5.0 (3) Isostearyl polygalactoside 10.0 (Average degree of polymerization 2.0, mono-body content 56% ) (4) Coconut oil fatty acid diethanol amide 3.0 (5) Chelating agent 0.1 (6) Suitable for fragrance (7) Suitable for dye (8) Residue of deionized water

The body soap produced by the conventional method with the above-mentioned formulation had an appropriate viscosity, had a rich and moisturizing good use feeling, and the skin after washing was moist and not moisturized. Further, when stored at 0 ° C., 25 ° C. and 50 ° C., all were stable and no separation or the like occurred.

Formulation Example 15 Solid soap (1) Glycerin 5.0 wt% (2) Beef tallow 20.0 (3) Isostearyl polyglucoside 10.0 (Average degree of polymerization 2.0, mono-body content 54%) (4 ) Castor oil 12.0 (5) Olive oil 3.0 (6) Caustic soda 6.0 (7) Ethanol 20.0 (8) Sucrose 5.0 (9) Cyclohexylguanidine 3.0 (10) EDTA 0.1 (11) Fragrance suitable (12) Dye suitable (13) Ion-exchanged water residue

The solid soap produced by the usual method with the above-mentioned formulation had an appropriate viscosity, had a rich and moisturizing good use feeling, and the skin after washing was moist and not moisturized. Further, when stored at 0 ° C., 25 ° C. and 50 ° C., all were stable and no separation or the like occurred.

Formulation Example 16 Acid Hair Dye Black-401 0.2 wt% Purple-401 0.3 Yellow-4 0.3 Benzyl Alcohol 5.0 Isostearyl Polyglucoside 10.0 (Average Degree of Polymerization 2.0 , Mono-body content 42%) Tetrahydrofurfuryl alcohol 12.0 Citric acid 2.0 Soybean protein hydrolyzate 0.1 Perfume proper amount Ion-exchanged water residual

With the above formulation, tetrahydrofurfuryl alcohol and benzyl alcohol were added to ion-exchanged water, and isostearyl polyglucoside was gradually added to this to prepare a viscous liquid. Black-No. 401, purple-
Nos. 401, Yellow-4, and soybean protein hydrolyzate were added to adjust the pH to 4.0 to 4.2 to obtain a uniform and viscous acidic hair dye composition.

This acidic hair dye does not drip from the hair during the hair dyeing process, has good spreadability, applicability, leveling property, dyeing property, and wash resistance, and, moreover, is suitable for the scalp. It was a safe and highly acidic acidic hair dye. The hair after use had a moist finish. In addition, when an acidic hair dye using xanthan gum and / or bentonite, which is a thickener conventionally used for acidic hair dye instead of isostearyl polyglucoside, was prepared as a comparative example, the hair dye is applied to the hair. At the time, it was inferior to isostearyl polyglucoside in all of the spreadability on hair, spreadability on hair, coatability, leveling property, dyeing property, washing resistance, and feeling after use.

Formulation Example 17 Acid Hair Dye Black-401 0.2 wt% Purple-401 0.3 Yellow-4 0.1 0.1 Benzyl alcohol 5.0 Isostearyl polyglucoside 3.0 (Average degree of polymerization 1.8) , Mono-body content 23%) Xanthan gum 0.5 Crosslinkable sodium polyacrylate 0.2 Tetrahydrofurfuryl alcohol 12.0 Collagen hydrolysate 0.2 Citric acid 2.0 Fragrance Suitable amount Ion-exchanged water Residual

The acidic hair dye prepared according to the formulation example 16 according to the above formulation does not drip from the hair during the hair dyeing treatment, and has spreadability, applicability, leveling property, dyeing property, and wash resistance. It was a safe and acidic hair dye which was good and had no irritation to the scalp. In addition, the hair after use had a moist finish.

Formulation 18 Acidic hair dye Black-401 0.2 wt% Purple-401 0.3 Yellow-4 0.1 Benzyl alcohol 5.0 Isomyristyl polyglucoside 4.0 (Average degree of polymerization 1.9) , Mono-body content 19%) Xanthan gum 0.5 Bentonite (Kunipia G, Kunimine Industries) 0.2 Tetrahydrofurfuryl alcohol 12.0 Citric acid 2.0 Keratin hydrolyzate 0.1 Perfume proper amount Ion-exchanged water residue

The acidic hair dye prepared according to Formulation Example 16 with the above formulation does not drip from the hair during the hair dyeing treatment, and has spreadability, applicability, leveling property, dyeing property, and wash resistance. It was a safe and acidic hair dye which was good and had no irritation to the scalp. In addition, the hair after use had a moist finish.

Compounding Example 19 Acid Hair Dye Black-401 0.2 wt% Purple-401 0.3 Yellow-4 0.1 Benzyl alcohol 5.0 Isostearyl polyglucoside 4.0 (Average degree of polymerization 2.1) , Mono-body content 24%) Xanthan gum 0.5 Bentonite (Kunipia G, Kunimine Industries) 0.2 Dimethylpolysiloxane 0.5 Tetrahydrofurfuryl alcohol 12.0 Citric acid 2.0 Glycerin 0.5 Polyoxyethylene (100 ) Hardened castor oil ester 1.0 Silk protein hydrolyzate 0.1 Fragrance appropriate amount Ion-exchanged water Residual

The acidic hair dye prepared according to the formulation example 16 with the above formulation does not drip from the hair during the hair dyeing treatment, and has extensibility, applicability, leveling property, dyeing property, and wash resistance. It was a safe and acidic hair dye which was good and had no irritation to the scalp. In addition, the hair had little damage after use and had a moist finish.

Formulation Example 20 Acid Hair Dye Black-401 0.2 wt% Purple-401 0.3 Yellow-4 0.1 Benzyl Alcohol 5.0 Isostearyl Polyglucoside 10.0 (Average Degree of Polymerization 1.9 , Mono-body content 47%) Tetrahydrofurfuryl alcohol 12.0 Citric acid 2.0 Glycerin 0.5 Elastin hydrolyzate 0.2 Polyoxyethylene (100) hydrogenated castor oil ester 1.0 Perfume proper amount ion-exchanged water Remnant

The acidic hair dye prepared according to Formulation Example 16 with the above formulation does not drip from the hair during the hair dyeing treatment, and has extensibility, coating property, leveling property, dyeing property, and wash resistance. It was a safe and acidic hair dye which was good and had no irritation to the scalp. In addition, the hair after use had a moist finish.

Blending Example 21 Acid Hair Dye Black-401 0.2 wt% Purple-401 0.3 Yellow-4 0.1 Benzyl alcohol 5.0 Isostearyl polygalactoside 10.0 (Average degree of polymerization 2.1) , Mono-body content 27%) Polyether-modified polysiloxane 0.5 Dimethylpolysiloxane 0.5 Tetrahydrofurfuryl alcohol 12.0 Citric acid 2.0 Glycerin 0.5 Carboxymethylcellulose 0.1 Polyoxyethylene (100) curing Castor oil ester 1.0 Keratin protein hydrolyzate quaternized salt 0.2 Fragrance appropriate amount ion-exchanged water residue

The acidic hair dye prepared according to the formulation example 16 with the above-mentioned formulation does not drip from the hair during the hair dyeing treatment, and has extensibility, coating property, leveling property, dyeing property, and wash resistance. It was a safe and acidic hair dye which was good and had no irritation to the scalp. In addition, the hair after use had a moist finish.

Formulation Example 22 Color rinse type hair dye Black-401 0.02 wt% Purple-401 0.03 Yellow-4 0.01 0.01 Benzyl alcohol 3.0 Isostearyl polyglucoside 10.0 (Average degree of polymerization 1 .8, mono content 56%) Polyether-modified polysiloxane 0.6 Tetrahydrofurfuryl alcohol 8.0 Citric acid 0.6 Glycerin 0.5 Octamethylcyclotetrasiloxane 3.0 Polyoxyethylene (100) Cured castor Oil ester 0.7 1,3-butylene glycol 15.0 Quaternized collagen protein hydrolyzate 0.2 Fragrance appropriate amount ion-exchanged water residual

The color-rinse type hair dye prepared according to Formulation Example 16 with the above-mentioned formulation does not drip from the hair during hair dyeing treatment, and has extensibility, coating property, leveling property, dyeing property, and durability. It was a safe acidic hair dye with good detergency and no irritation to the scalp. In addition, the hair after use had a moist finish. In addition, when an acidic hair dye using xanthan gum and / or bentonite, which is a thickener conventionally used for acidic hair dye instead of isostearyl polyglucoside, was prepared as a comparative example, the hair dye is applied to the hair. At the time, it was inferior to isostearyl polyglucoside in all of the spreadability on hair, spreadability on hair, coatability, leveling property, dyeing property, washing resistance, and feeling after use.

Formulation Example 23 Color rinse type hair dye Black-401 0.02 wt% Purple-401 0.03 Yellow-4 0.01 0.01 Benzyl alcohol 3.0 Isostearyl polyglucoside 10.0 (Average degree of polymerization 2 0.0, mono content 43%) Polyether-modified polysiloxane 0.2 Dimethylpolysiloxane 0.5 Tetrahydrofurfuryl alcohol 8.0 Citric acid 0.6 Glycerin 0.5 Octamethylcyclotetrasiloxane 3.0 Polyoxy Ethylene (100) hydrogenated castor oil ester 0.7 1,3-butylene glycol 15.0 xanthan gum 0.5 bentonite 0.3 quaternized silk protein hydrolyzate 0.2 perfume proper amount ion-exchanged water residual

The color rinse type hair dye prepared according to the formulation example 16 with the above-mentioned formulation does not drip from the hair during the hair dyeing treatment, and has extensibility, applicability, leveling property, dyeing property, and durability. It was a safe acidic hair dye with good detergency and no irritation to the scalp. In addition, the hair after use had a moist finish.

Formulation 24 Color rinse type hair dye Black-401 0.02 wt% Purple-401 0.03 Yellow-4 0.01 0.01 Benzyl alcohol 3.0 Isostearyl polyglucoside 7.0 (Average degree of polymerization 2 .1, mono content 27%) Polyether modified polysiloxane 0.2 Amino modified polysiloxane 0.5 Tetrahydrofurfuryl alcohol 8.0 Citric acid 0.6 Glycerin 0.5 Octamethylcyclotetrasiloxane 3.0 Chloride Stearyl trimethyl ammonium 0.1 Polyoxyethylene (100) hydrogenated castor oil ester 0.7 1,3-butylene glycol 15.0 Xanthan gum 0.5 Keratin protein hydrolyzate 0.2 Crosslinked sodium polyacrylate 0.3 Perfume Appropriate amount of deionized water

The color-rinse type hair dye prepared according to the formulation example 16 with the above-mentioned formulation does not drip from the hair during the hair dyeing treatment, and has extensibility, coating property, leveling property, dyeing property, resistance to It was a safe acidic hair dye with good detergency and no irritation to the scalp. In addition, the hair after use had a moist finish.

Formulation Example 25 Color rinse type hair dye Black-401 0.02 wt% Purple-401 0.03 Yellow-4 0.01 0.01 Benzyl alcohol 3.0 Isostearyl polyglucoside 10.0 (Average degree of polymerization 1 9.9, mono-content 52%) Amino-modified polysiloxane 0.6 Tetrahydrofurfuryl alcohol 8.0 Citric acid 0.6 Glycerin 0.5 Octamethylcyclotetrasiloxane 3.0 Polyoxyethylene (100) hydrogenated castor oil Ester 0.7 1,3-butylene glycol 15.0 Bentonite 0.3 Soybean protein hydrolyzate 0.1 Perfume proper amount Ion-exchanged water residual

The color rinse type hair dye prepared according to Formulation Example 16 with the above formulation did not drip from the hair during the hair dyeing treatment, and had extensibility, coating property, leveling property, dyeing property, resistance to dyeing. It was a safe acidic hair dye with good detergency and no irritation to the scalp. In addition, the hair after use had a moist finish.

Formulation 26 Oxidizing hair dye first agent Propylene glycol 5.0 wt% Polyethylene glycol 400 5.0 Isopropanol 0.1 Sodium hydrosulfite 0.5 Isostearyl polyglucoside 7.0 (Average degree of polymerization 1.9, Mono-body content rate 49%) L-ascorbic acid 0.5 EDTA 0.5 ammonia water 7.0 para-phenylenediamine 1.0 resorcin 1.0 meta-aminophenol 0.1 meta-phenylenediamine 0.01 perfume proper amount ion exchange Water Residual second agent Hydrogen peroxide 30% 15.0 Phosphate buffer adjusted to pH 3 Methylparaben 0.1 Sodium stannate 0.1 EDTA ・ 2 sodium 0.1 Deionized water Residual

A first agent and a second agent having the above-mentioned formulation were prepared by a conventional method, and these were mixed at a weight ratio of 1: 1 before use to obtain an oxidative hair dye. This oxidative hair dye does not drip from the hair during hair dyeing, has good spreadability, applicability, level dyeability, and dyeability, and is a safe oxidative dye that does not irritate the scalp. It was hair. In addition, the hair had little damage after use and had a moist finish.

An oxidative hair dye using polyoxyethylene (5) octyl phenyl ether, which is a thickener conventionally used for oxidative hair dye, instead of isostearyl polyglucoside was prepared as a comparative example. When the hair dye is applied to the hair, it drips or spreads on the hair,
It was inferior to isostearyl polyglucoside in all of the coatability, level dyeability, dyeability, and feel after use.

[0093]

As described above, the thickening gelling agent of the present invention has a content of branched aliphatic monoglycoside with respect to the total amount of branched aliphatic polyglycoside of 5% by weight or more, and
The average degree of polymerization of the branched aliphatic polyglycoside is 1.8 to 2.
By setting it to 1, it has an effect of exhibiting an excellent thickening gelling ability, and when applied to the skin, an excellent moisturizing property and a feeling of use are continuously obtained.

[Brief description of drawings]

FIG. 1 is a diagram showing a change in viscosity-enable gel according to the average degree of polymerization of isostearyl polyglucoside, which is an example of the present invention.

Claims (2)

[Claims] 1. In a thickening gelling agent containing a branched aliphatic polyglycoside represented by the following general formula 1, a branched aliphatic monoglycoside having a degree of polymerization n of 1 is added to the total amount of the branched aliphatic polyglycoside. Content of 5% by weight or more, and the average degree of polymerization of the branched aliphatic polyglycoside as a whole is 1.
A thickening gelling agent characterized by being present in the range of 8 to 2.1. ## STR00001 ## Gn-O-R (In the formula, Gn means a residue obtained by removing a glycosidic hydroxyl group from a monosaccharide G dehydrated and condensed at a degree of polymerization of n.
n is an integer of 1 or more. Further, R means a branched fatty chain having a glycoside bond with Gn and having a total carbon number of 8 to 32. ) 2. A cosmetic containing the thickening gelling agent according to claim 1.