JPH09202725A - Cosmetic - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a cosmetic excellent in moisture retaining effect on skin, slight in sticky feeling and improved in emulsion stability, by blending a cosmetic prescription with a specific component. SOLUTION: This cosmetic is obtained by a cosmetic prescription with a glycosylpolyglycerol of formula I (one of R groups is a glucose residue and the rest are H; (n) is 1-9). The glycosylpolyglycerol of formula I is obtained, for example, by reacting a polyglycerol of formula II ((n) is 1-9) with a saccharide containing a glycerol skeleton using a glycosyltransferase or a glucohydrolase or a saccharide phosphorylase. The cosmetic is useful, for example, as a skin lotion, a milky lotion, a cream, a pack, a foundation, a hair dressing agent, a shampoo, a rinse, etc.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cosmetic having a high moisturizing effect on the skin, no sticky feeling, and good emulsion stability by incorporating glucosyl polyglycerol as an active ingredient.

[0002]

2. Description of the Related Art Conventionally, many cosmetics which are expected to have a skin improving effect and a moisturizing effect are commercially available. Moisture retention in the skin is an indispensable factor for keeping the skin healthy, and studies on substances relating to moisturization have been actively conducted, and various moisturizers have been provided. Among them, water-soluble polyhydric alcohols have been widely used in many cosmetics because they are excellent in water retention and hygroscopicity. However, among these water-soluble polyhydric alcohols, widely used, for example, cosmetics containing glycerin, polyglycerin, maltitol, etc., have excellent skin improving effect and moisturizing effect, but have a strong sticky feeling at the time of use. However, the coating property (spreading to the skin at the time of coating) was poor, which was not desirable because it was functional. On the other hand, cosmetics containing propylene glycol, 1,3-butylene glycol, etc. have less sticky feeling at the time of use and have good coatability, but lack the skin-improving effect and moisturizing effect. It only lasted about 2 hours, and it was not always satisfactory such as lack of sustainability. In addition, there is a problem that the stability of the system is impaired by adding an amount in which the effect can be obtained.

[0003]

The present inventor has conducted diligent research to solve the above-mentioned drawbacks in view of such circumstances, and as a result, by incorporating a specific component in a cosmetic formulation, On the other hand, they have found that a cosmetic having an excellent moisturizing effect, a less sticky feeling, and good emulsion stability can be obtained, and thus completed the present invention.

[0004]

Means for Solving the Problems That is, the present invention is characterized in that glucosyl polyglycerol represented by the following general formula (1) is added as an active ingredient in a cosmetic formulation, to impart a moisturizing effect and a wet feeling. The present invention relates to a cosmetic composition which has an effect, lasts for a long time, has less sticky feeling, and has good emulsion stability.

[0005]

[Chemical 1]

Hereinafter, the configuration of the present invention will be described in detail. The glucosyl polyglycerol used in the present invention is obtained by reacting polyglycerin with a saccharide having a glucose skeleton using a glycosyltransferase, a sugar hydrolase, or a glycosyl phosphatase. Chemically, it can be obtained by reacting polyglycerin or polyglycerin partially protected with hydroxyl groups with glucose or glucose partially protected with hydroxyl groups.

Polyglycerin is represented by the following general formula (2):

Embedded image

Specific examples thereof include diglycerin, triglycerin, tetraglycerin, pentaglycerin, hexaglycerin, heptaglycerin, octaglycerin, nonaglycerin and decaglycerin. Even if a mixture of these polyglycerins is used, there is no problem. There is no.

From the viewpoint of safety, cost, and easiness of production, a production method of reacting polyglycerin with a saccharide having a glucose skeleton using a glycosyltransferase, a sugar hydrolase, or a glycosyl phosphate degrading enzyme is preferable. For example, glucosyl polyglycerol can be obtained by dehydration condensation reaction of polyglycerin and glucose using glucoamylase as an enzyme, but all the raw materials used are highly safe, inexpensive and easily available. Further, by using polyglycerin in excess with respect to glucose, the main composition of the reaction becomes glucosyl polyglycerol and unreacted polyglycerin.
Unreacted polyglycerin can be removed by operations such as distillation, solvent fractionation, and chromatography, so that high-purity glucosyl polyglycerol can be easily obtained.

The cosmetic of the present invention uses glucosyl polyglycerol as a moisturizing active ingredient, but may contain other known moisturizing ingredients within the scope of achieving the object of the present invention. Known moisturizing components include, for example, polyethers such as polyethylene glycol and polypropylene glycol, glycerin, 1,3-butylene glycol, propylene glycol, polyhydric alcohols such as maltitol, further amino acids, pyrrolidone carboxylate, Examples include NMF components such as lactate and urea, mucopolysaccharides and proteins. Further, in the skin cosmetic of the present invention, if desired, various components conventionally used in cosmetics such as oil, lower alcohol, surfactant, antiseptic, antiseptic, fragrance, thickener, and antioxidant Agent, chelating agent, p
An H preparation agent, a dye, an ultraviolet absorber, a skin activator, water and the like can be added.

The cosmetic composition of the present invention can be formulated, for example, as a lotion, an emulsion, a cream, a pack, a foundation, etc. by appropriately blending the moisturizing component and any of these optional components.
It can be used in various product forms. Furthermore, glucosyl polyglycerol, which is the active ingredient of the present invention, is also used for cosmetics required to have a wet feeling-imparting effect on hair, for example, hair dressing, shampoo, scalp such as rinse, and cosmetics for hair. be able to. Hereinafter, the present invention will be described in detail with reference to Synthesis Examples, Examples, and Comparative Examples, but the present invention is not limited thereto. In the synthesis examples, examples and comparative examples,% is wt%.

[0012]

[Synthesis Example 1] 100 g of water, 740 g of diglycerin, and 160 g of glucose were mixed and dissolved, and glucoamylase (manufactured by Novo Nordisk Industries Ltd., trade name "AMG30"
0 L ") was added and reacted at 50 ° C for 96 hours.
The reaction product contained 23% glucosyl diglycerol by gas chromatographic analysis. After removing the enzyme as usual, diglycerin was removed by thin film distillation. Purification with an ion exchange resin gave 302 g of a colorless transparent viscous liquid. It contained 79% glucosyl diglycerol by gas chromatographic analysis.

[0013]

[Synthesis Example 2] 10 g of the composition obtained in Synthesis Example 1 was subjected to activated carbon chromatography and fractionated with an ethanol concentration gradient to obtain 7.6 g of a colorless transparent viscous liquid. This one is
It contained 99% glucosyl diglycerol by gas chromatographic analysis.

[0014]

Example 1 and Comparative Examples 1-2 A lotion having the composition shown in Table 1 was prepared, and the moisture content in the stratum corneum was measured to evaluate the moisturizing property. The results are shown in FIG. (Evaluation Method of Moisturizing Property) 20 μl / 16 cm of the lotion of Example 1 and Comparative Examples 1 and 2 was applied to the forearm flexion side of 10 female panels.
Apply evenly to ² and temperature 20 ℃, humidity 60%
The water content in the corneum was measured with the use of a high frequency conductivity measuring device for 120 minutes under the above condition, and the average value of 10 panelists was shown.

[0015]

[Table 1]

[0016]

FIG.

As is apparent from FIG. 1, the cosmetic of the present invention has excellent moisturizing properties, and its moisturizing effect lasted for a long period of time.

[0018]

Examples 2 to 3 and Comparative Examples 3 to 4 Creams having the compositions shown in Table 2 were prepared and their usability was evaluated. The results are also shown in Table 2. (Evaluation of usability) A use test was conducted by 10 female panels, and "less sticky feeling", "moderately moisturizing feeling", and "about sticky feeling", "moisturizing feeling", and "applicability" were selected. The number of respondents who answered, "It spreads well when applied."

[0019]

[Table 2]

As is clear from the results shown in Table 2, the cosmetics of the present invention showed excellent performance in terms of usability.

[0021]

Example 4 and Comparative Example 5 An emulsion having the composition shown in Table 3 was prepared and the emulsion stability was evaluated. The results are shown in Table 3. (Evaluation of Emulsion Stability) After the emulsions of Example 4 and Comparative Example 5 were prepared, they were allowed to stand at 50 ° C. for 20 days, and the emulsified particle diameters before and after the standing were measured using a laser diffraction type particle size distribution measuring device.

[0022]

[Table 3]

As is clear from the results shown in Table 3, the cosmetics of the present invention had excellent emulsion stability.

[0024]

Example 5 Foundation (%) Stearic Acid 8.0 Cetostearyl Alcohol 2.0 Liquid Isoparaffin 10.0 Isocetyl Octanoate 6.0 Lanolin 2.0 Cholesterin 0.5 Sorbitan Monostearate 2.0 Monostearin Acid polyoxyethylene (20) sorbitan 1.0 Butylparaben 0.2 Propylene glycol 3.0 Glucosyl polyglycerol (Synthesis example 1) 4.0 Triethanolamine 1.0 Pigment 15.0 Fragrance Suitable amount Purified water Amount to do

[0025]

Example 6 Cleansing Cream (%) Paraffin 5.0 Cetyl Alcohol 1.5 Vaseline 18.0 Liquid Paraffin 28.0 Glycerin Monostearate 3.0 Polyoxyethylene (20) Monolaurate 3.0 Glucosyl Polyglycerol (Synthesis example 1) 3.0 Propylene glycol 2.0 Perfume Suitable amount Purified water Amount based on 100 as a whole

[0026]

Example 7 Pack (%) Vinyl acetate resin emulsion 15.0 Polyvinyl alcohol 10.0 Olive oil 3.0 Zinc white 8.0 Kaolin 7.0 Ethyl alcohol 5.0 Glucosyl polyglycerol (Synthesis example 1) 5.0 Perfume Suitable amount Purified water 100%

[0027]

Example 8 Hair rinse (%) Cetyl trimethyl ammonium chloride 1.0 Cetyl alcohol 3.0 Liquid paraffin 3.0 Methyl paraben 2 Polyoxyethylene (60) glyceryl monoisostearyl ether 0.7 Glycerin monooleate 0. 5 Glycerin 5.0 Glucosyl polyglycerol (Synthesis Example 1) 3.0 Perfume Suitable amount Purified water 100 parts as a whole

[0028]

[Example 9] Aerosol hair styling agent (%) Stearyl trimethyl ammonium chloride 0.8 Cetyl alcohol 1.0 Dimethyl silicone oil 2.0 Polyoxyethylene (60) hydrogenated castor oil 2.5 Polyvinylpyrrolidone 0.5 Liquid paraffin 1. 0 Glycerin 3.0 Glucosyl polyglycerol (Synthesis example 1) 2.0 Methylparaben 0.2 Ethyl alcohol 10.0 Perfume Suitable amount Purified water 100 parts based on total

[0029]

[Effects of the Invention] The cosmetics containing glucosyl polyglycerol of the present invention as an active ingredient have a sufficient moisturizing effect and an effect of imparting a wet feeling, and the moisturizing effect lasts for a long time and has a small sticky feeling, and emulsion stability It was excellent.

[0030]

[Brief description of drawings]

FIG. 1 is a diagram showing the results of the moisturizing test of Example 1 and Comparative Examples 1 and 2.

Claims (1)

[Claims] 1. A cosmetic comprising glucosyl polyglycerol represented by the following general formula (1) as an active ingredient. Embedded image