JPH09202355A - Sterilizing blister packaging cardboard and blister package - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a sterilizing blister packaging cardboard which is air- permeable and which does not generate paper powder or the like on unsealing and leaves a trace at the unsealing time and a blister package by use of the cardboard. SOLUTION: This blister packaging cardboard is made of a composite sheet in which thin paper 11 and a laminate film 13 are stuck to each other. The laminate film 13 is provided with a heatseal layer on the blister body to be sealed, as one surface layer and an easily separable part which is separated by a weaker force than the heatseal strength between the seal layer and the blister. A number of pierced holes are bored on respective layers except the thin paper of the composite sheet.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a mount for a sterilization blister package suitable for packaging medical instruments such as syringes, and more particularly, to facilitate and unsealing of a mount heat-sealed by heat sealing. The present invention relates to a sterilization blister packaging mount in which a trace of unsealing is left on the part and a sterilization blister packaging body blister-packed using the blister packaging mount.

[0002]

2. Description of the Related Art Attempts have been made to apply blister packaging to the packaging of medical instruments such as syringes and surgical gloves. This is because a blister formed by molding a plastic sheet to form a storage section, and a blister mount sealing the storage section of the blister are heat-sealed at the periphery of the blister, and the contents such as a syringe are sealed, and then ethylene oxide is sealed. Gas (EO
G) Sterilization, γ-ray sterilization, and the like are performed to sterilize the contents of each package. For the characteristics required as a backing sheet for packaging medical equipment, from the viewpoint of preventing unauthorized opening and guaranteeing safety, there are traces of opening in the opening part, and it is necessary to perform sterilization work such as EOG sterilization so that gas permeation is possible. It has the property that there is no generation of paper powder or dropping of paper fibers when opened, and
There is a so-called easy peel property that can be easily opened without using a device.

The sterilizable mount has a heat-sealing property obtained by coating sterilized paper having sterilization suitability with a sealing agent or a heat-seal lacquer, or sterilized paper mixed with fibers of polyethylene resin or polypropylene resin. They were things that were held, sheet-like non-woven fabrics made from high-density polyethylene fibers, and the like. However, a mount coated with a sealing agent or a heat-seal lacquer is difficult to achieve both the gas permeability, the trace of opening, and the easy peeling, which are the required qualities of a blister mount for medical device packaging.
Sheet-like non-woven fabric made of high density polyethylene fiber and polyethylene resin or polypropylene resin mixed fiber is difficult to leave traces when opened, cost is high, blister material is restricted There is.

[0004]

SUMMARY OF THE INVENTION The present invention has been made in order to eliminate the above-mentioned problems relating to a sterilization blister packaging mount made of thin paper and a plastic film, and has gas permeability and is opened. An object of the present invention is to provide a mount for sterilization blister packaging in which paper dust or the like is not generated at some time and a trace at the time of opening and a blister package which is blister-packed using the mount for blister packaging.

[0005]

Means for Solving the Problems A first invention of the present invention is:
What is claimed is: 1. A blister packaging mount comprising a composite sheet obtained by laminating thin paper and a laminated film, wherein the laminated film has as one surface layer a sealing layer that is heat-sealed to a blister to be sealed, the sealing layer Each layer other than the thin paper of the composite sheet, comprising an easy-separation portion that separates with a strength weaker than the heat-sealing strength between the blister and the blister, characterized in that a large number of through holes are formed, It is a mount for blister packaging.

A second aspect of the invention is a sterilization blister packaging mount characterized in that the air permeability of the composite sheet is 1000 seconds or less (according to JIS P8117).

The third invention is that the delamination strength between the sealing layer and the non-sealing layer of the laminated film or the cohesive failure strength of the non-sealing layer is 100 to 2000 g / 15 mm width (J
(According to ISZ1707), a mount for sterilization blister packaging.

The fourth invention is characterized in that the through holes formed in each layer other than the thin paper have a diameter of 100 to 1500 μm or a density of 50 to 200 holes / cm ^2. It is a mount for blister packaging for sterilization.

A fifth aspect of the invention is a sterilization blister packaging mount characterized in that the through-holes are melting holes formed by laser light irradiation.

The sixth invention is the first invention to the fifth invention.
It is a blister package for sterilization, which is blister-packed using the mount for blister packaging for sterilization according to the invention.

As described above, the sterilization blister packaging mount of the present invention is a composite sheet obtained by laminating thin paper and a laminated film containing a portion having an interlayer strength weaker than the adhesive strength between the seal layer and the body to be sealed. Since each layer other than the thin paper is provided with a large number of through holes, it is possible to maintain appropriate air permeability and allow gases, vapors and the like necessary for sterilizing the contents to pass through. In addition, since the thin paper itself has no through holes, bacteria do not enter inside. Furthermore, since the easy-opening property and the trace of the opening can be exhibited by the laminated film serving as the sealant layer, it is difficult to generate the fluff of the thin paper fiber and the peeling, which are problems when the heat-sealed portion is opened.

[0012]

BEST MODE FOR CARRYING OUT THE INVENTION The present invention will be described below with reference to Examples. 1 and 2, reference numeral 10 denotes a blister packaging mount for sterilization according to the present invention. The blister packaging mount 10 is configured by laminating a laminated film 13 to a thin paper 11 with an adhesive layer 12 interposed therebetween. Through holes 14 are formed in the adhesive layer 12 and the laminated film 13 other than 11.

As the thin paper 11, fine paper, pure white roll paper, bleached kraft paper, and the like can be suitably used in addition to normally used sterilized paper. Use basis weight is 40-100g / m
It is about ² . Since it is used as a packaging material for medical equipment, it needs to have sterilization suitability such as EOG sterilization, and of course appropriate air permeability is required. Strong tensile strength is also an important factor when selecting thin paper. The tensile strength of the thin paper 11 is 3.0 to 20.0 kg / 15 in the longitudinal direction.
mm width, lateral direction 1,0 to 15.0 kg / 15 mm
The width is preferably about (according to JIS P8113), and the air permeability is preferably about 10 to 500 seconds. If necessary, the display layer 15 may be provided with printing ink or the like on the side of the thin paper laminated film not bonded.

The adhesive layer 12 is for laminating and adhering a laminated film 13 to be described later to the thin paper 11, and the thin paper 11 and the laminated film 13 are laminated by dry laminating via the adhesive layer 12. As the adhesive layer 12, a well-known two-component reactive adhesive for dry lamination such as a polyester adhesive or a polyurethane adhesive can be used, and the coating amount thereof is preferably 0.5 to 10 g / m ² .

The laminated film 13 is for thermally adhering the blister packaging mount 10 to the blister 20 and for causing delamination between the layers of the laminated film when the blister packaging mount 10 is peeled from the blister 20. As the layer structure of the laminated film 13, for example, a polyethylene-based multilayer co-extrusion easy-opening film can be used. If a specific example is shown, the layer structure is polyethylene 13a / tie layer 13b / polyethylene 1 as shown in FIG.
It is composed of 5 layers of 3c / tie layer 13d / polyethylene 13e. The total thickness is preferably from 40 to 80 μm. If it is less than 40 μm, it is difficult to control the thickness of each layer, and problems such as difficulty in developing stable easy-opening property occur. If it exceeds 80 μm, the total thickness of the blister packaging mount 10 increases and heat transfer deteriorates, resulting in poor sealing. This is not preferable because problems such as easy to occur occur. The tie layer here is an adhesive polyolefin resin. This example is preferable when the material of the blister 20 is polyethylene, polypropylene, polystyrene, polyvinyl chloride or the like. It can be applied to various blisters by changing one outer surface layer of the laminated film according to the material of the blisters.

When the outermost polyethylene 13e surface of the laminated film is superposed on the blister 20 which is the object to be sealed and the peripheral portion thereof is heat-sealed, and then the blister packaging mount 10 is peeled from the sealing portion, the laminated film 1
The peel strength at the film interface (13d / 13e) of No. 3 is set to be weaker than the adhesion strength between the polyethylene 13e as the sealing layer and the blister 20 as the sealed body, and weaker than the cohesive failure strength of the tie layer 13d. Because there is
The film interface (13d / 13e) becomes an easy peel and is peeled off smoothly from the interface between the tie layer 13d and the polyethylene 13e, and the polyethylene 13e remains as a trace A on the periphery of the blister 20 (see FIG. 2 (a)).

Further, the cohesive failure strength of the tie layer 13d is weaker than the adhesive strength between the polyethylene 13e which is the sealing layer and the blister 20 which is the sealed body, and is weaker than the film interface (13d / 13e) of the laminated film 13. By setting, the tie layer 13d is cohesively destroyed and halved, and a part of the tie layer 13d is caught on the blister packaging mount 10 side, but a part of the tie layer 13d remains as a trace B on the periphery of the blister 20 (see FIG. 2 (b )reference).

The composite sheet composed of the thin paper 11 and the laminated film 13 dry-laminated through the adhesive layer 12 described above has a through-hole formed in the adhesive layer and the laminated film excluding the thin paper by being irradiated with laser light from the laminated film surface. 14 is drilled. This through hole 14 is used for the sterilization blister package 50.
When introducing sterilization such as EOG sterilization after, the gas and steam are introduced, and the size of the through holes is 100 to 1500 μm in diameter or 50 to 200 in density.
The number of pieces / cm ² is preferable. If the diameter is less than 100 μm or the density is less than 50 pieces / cm ² , the introduction of gas or vapor may be insufficient or it may take more time than necessary, which may impair sterilization and workability. .
In addition, the diameter is 1500 μm or more, or the density is 200
If the number of cells / cm ² or more is reached, bacteria may enter the inside of the blister package through the through holes after sterilization, which is not preferable.

[0019]

Embodiments of the present invention will be described below in more detail with reference to FIGS. <Example 1> As the thin paper 11, a high-quality paper having a basis weight of 64 g / m ² (trade name: KFD, manufactured by Nippon Paper Industries Co., Ltd.) is prepared, and a display layer 15 is provided on one surface thereof with a printing ink. 50 μm as laminated film 13 having easy opening property
Thick polyethylene-based 5-layer co-extruded film (trade name Reyopeel RX, UCB Transpac)
S. A. Prepared). Display layer 1 of prepared thin paper 11
On the side not subjected to 5, the laminated film 13 is coated with a two-component reactive polyurethane adhesive (trade name: Adcoat 30
No. 0, manufactured by Toyo Morton Co., Ltd.) and laminated by a dry lamination method (coating amount 5 g / m ² ) to form a composite sheet.

Next, a laser beam is applied from the laminated film surface side of this composite sheet using a laser aperture machine (manufactured by Nidaiki Co., Ltd.) to form 100 to 120 holes / cm ² of 200 to 300 μm in diameter. Then, the mount 10 for blister packaging for sterilization was obtained. Since it is a laser beam, it is possible to open the fine holes in all layers except the thin paper without opening the thin paper.

As the blister 20, a sheet whose innermost surface is made of polyethylene resin is molded, and a container 30 such as a syringe is placed inside the molded sheet, and the laminated film 13 surface of the sterilization blister packaging mount 10 is blister 2.
The blister packaging mount was placed so as to overlap the inner surface of No. 0, and the periphery of the blister was heat-sealed and hermetically sealed to prepare a sterilization blister package 50.

In order to confirm the effect of easy opening, the blister packaging mount was peeled off from the heat-sealed part. It was peeled off from the film interface (13d / 13e) of the laminated film, and the polyethylene 13e of the innermost layer of the laminated film was broken. Then, it remained as an opening trace A on the heat-sealed portion of the blister. The thin paper did not cause delamination or generate paper dust.

[0023]

EFFECTS OF THE INVENTION Since the present invention has the above-mentioned constitution, it is possible to leave a trace of the innermost layer film of the laminated film layer on the heat-sealed portion of the blister at the time of opening, and it is obvious that the opening has been made. . In addition, the peeling strength between the mount and the blister and the trace of unsealing at the time of unsealing can be expressed by the laminated film, so fluffing and paper peeling of the paper fiber which is a problem when unsealing is less likely to occur Since there is no need for delamination strength, there is an effect that the selection range of paper is expanded.

[Brief description of drawings]

FIG. 1 is a cross-sectional view of a mounting sheet for blister packaging for sterilization according to one embodiment of the present invention.

FIG. 2 is a partial cross-sectional view showing a state in which a part of the mounting sheet for sterilizing blister packaging heat-sealed in the blister is opened, and (a) is a tie layer 13d and polyethylene 13e.
The polyethylene 13e is peeled off smoothly from the interface of the blister 20 and remains as a trace A on the peripheral edge of the blister 20. In FIG.
Blister 2 partially with polyethylene 13e
This shows a state in which trace B remains on the periphery of 0.

FIG. 3 is a cross-sectional view of a laminated film.

[Explanation of symbols]

 10 ... Sterilization blister packaging mount 11 ... Thin paper 12 ... Adhesive layer 13 ... Laminated film 13a ... Polyethylene 13b ... Tie layer 13c ... Polyethylene 13d ... Tie layer 13e ... Polyethylene 14 ... Through hole 15 ... Indication Layer 20 Blister 30 Inclusions 50 Sterilization blister package A Trace B Trace

Claims (6)

[Claims] 1. A blister packaging mount comprising a composite sheet obtained by laminating a thin paper and a laminated film, wherein the laminated film has a seal layer for heat-sealing in a blister as an object to be sealed as one surface layer. However, each layer other than the thin paper of the composite sheet is provided with a large number of through holes. Characteristic blister packaging mount for sterilization. 2. The sterilization blister packaging mount according to claim 1, wherein the composite sheet has an air permeability of 1000 seconds or less (according to JIS P8117). 3. The delamination strength between the sealing layer and the non-sealing layer of the laminated film or the cohesive failure strength of the non-sealing layer is 1.
00-2000g / 15mm width (JIS Z1707
The blister packaging mount for sterilization according to claim 1 or 2, characterized in that 4. The through holes formed in each layer other than the thin paper have a diameter of 100 to 1500 μm or a density of 50 to 200 holes / cm ^2. 2. The sterilization blister packaging mount according to 2 or 3. 5. The through hole is a fusion hole formed by irradiation with a laser beam.
The blister packaging mount for sterilization according to. 6. A sterilization blister package, which is blister-packed using the sterilization blister packaging mount according to any one of claims 1 to 5.