JPH09157114A - Fumigant composition for controlling noxious insect - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide the subject composition containing 3-(2-methoxyphenyl)-5- methoxy-1,3,4-oxadiazol-2-(3H)-one as an active component and enabling the fumigation with the active component at a prescribed concentration. SOLUTION: The objective composition contains 3-(2-methoxyphenyl)-5- methoxy-1,3,4-oxadiazol-2(3H)-one as an active component in an amount to keep the concentration of >=45mg/m<3> , especially 45-70mg/m<3> in fumigation treatment. The composition exhibits especially excellent controlling effect on pyrethroid-resistant cockroach. The composition enables the control of cockroach living under furniture or at a corner of a room in high efficiency. The controlling effect is higher than the effect attained by the combined use of pyrethroidal compounds and the agent exhibits sufficient effect even by the single use to ensure economical merit and safety.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a fumigant composition for controlling pests, and more particularly to a fumigant composition for controlling pests capable of exerting an excellent controlling effect on pyrethroid-resistant cockroaches.

[0002]

2. Description of the Related Art Conventionally, as a method for exterminating insect pests by fumigating an insecticidal drug in a short time, a so-called fumigant which mixes the drug with a combustion agent and emits the agent by burning and smoke of the combustion agent is known. The method used is generally used, but since this method requires the combustion of a combustion agent that generates highly toxic smoke, it has the drawback of being accompanied by irritating odor due to smoke emission, danger to the human body, and risk of fire. Therefore, in order to eliminate the drawbacks, an insecticide is mixed with azodicarbonamide, and the mixture is indirectly heated to thermally decompose azodicarbonamide without combustion, and the action of the thermally decomposed gas causes insecticide. A method for exterminating harmful insects by effectively fumigating a drug (Japanese Patent Publication No. 52-28842) has been proposed.

As a drug used in such a method for exterminating pests, various pyrethroid-type insecticides and various other insecticides are known. For example, a pyrethroid-type compound is smoked in the air. A method for exterminating cockroaches, which is characterized in that they are dispersed in an aqueous solution, has been disclosed (JP-A-53).
-96321). In addition to these, organic phosphorus compounds, carbamate compounds, and the like have been used as the active ingredients of fumigant compositions used for these fumigants. Among them, pyrethroid compounds have a unique mechanism of action,
It has also become widely used due to its low toxicity. Thus, as one of the effective means for controlling cockroaches, it has been known to fumigate the active ingredient as a fumigant in the air. However, as the frequency of use has increased, cockroaches have significantly developed resistance to pyrethroid insecticides, making it impossible to obtain a sufficient control effect.

In order to solve this problem, the pyrethroid compound is highly lethal to cockroaches resistant to 3-
(2-Methoxyphenyl) -5-methoxy-1,3,4
-Oxadiazol-2 (3H) -one was developed and its excellent pest control effect is known (D. Ambro.
si et al (1979): Proc. Brit. P
rot. Conf, Pests and diseases
es, p. 533). Then, this drug attracted attention for its use as a fumigant for a pyrethroid resistance preparation,
Since the stability, especially the thermal stability, was poor, it was necessary to use a stabilizer in combination. As a result of studying this, it has been found that a phenolic compound and / or sorbitan monooleate as a stabilizer, or piperonyl butoxide as the stabilizer can be used as a fumigant for heating (Patent Publication 4). -11523 publication).

The use of the above-mentioned compound as a fumigant was examined, and it was found that it is preferable to use it in combination with a pyrethroid compound, since it has a poor knockdown effect and a flushing effect. For example, it has been shown that the combined use with permethrin improves transpiration and lethal effects (Sumitomo Chemical (19
88), pp. 37-45). However, as described above, cockroaches have already developed resistance to pyrethroid compounds, and in recent years resistance has further developed, and the effect of using a pyrethroid compound in combination has not been obtained. Rather, the pyrethroid-type compound has a repellent action against cockroaches, and a sufficient control effect has not been obtained.

[0006]

SUMMARY OF THE INVENTION An object of the present invention is to solve the above problems and provide a fumigant composition for controlling pests, which is excellent in controlling pyrethroid-resistant cockroaches.

[0007]

Means for Solving the Problems As a result of intensive investigations by the present inventors, conventionally, it is considered that the cockroaches are not sufficiently effective in actual use, and that they must be used in combination with pyrethroid compounds. 3- (2-methoxyphenyl) -5-methoxy-1,3,4-oxadiazole-
The present invention has been accomplished by finding a fumigant composition for controlling pests which solves the above problems by fumigating the above-mentioned active ingredient at a specific concentration with 2 (3H) -one as the active ingredient. That is, the above-mentioned active ingredient has a basic lethal effect on cockroaches sufficiently, but in actual use scenes, for example, in order to fully exert its control effect in indoors and warehouses, the flushing effect and the pyrethroid compound have. It was largely due to the synergistic action with the knockdown effect. However, by fumigating at a specific concentration different from the conventional one, it is possible to efficiently control cockroaches that live in the shade and room corners, and further to increase the control effect compared with the case where a pyrethroid compound is used in combination. I found it. Further, the pyrethroid compound has a repellent action, and if the amount used is increased, the repellent action is enhanced, leading to a decrease in the controlling effect, which is a problem. Therefore, even if the amount used is increased, such a problem does not occur, and as a result of studying the usable active ingredient and its usage form, the present invention has been achieved.

That is, the object of the present invention is solved by the following fumigant composition for controlling pests. (1) An amount of 3- (2-methoxyphenyl) -5 that can be present in the air by fumigation at 45 mg / m ³ or more.
-Methoxy-1,3,4-oxadiazole-2 (3
H) -one as an active ingredient, a fumigant composition for controlling pests. (2) An amount of 3- (2-methoxyphenyl)-that can be present in the air at 45 to 70 mg / m ³ by fumigation.
5-methoxy-1,3,4-oxadiazole-2 (3
H) -one as an active ingredient, a fumigant composition for controlling pests.

The active ingredient of the fumigant composition for controlling pests of the present invention is 3- (2-methoxyphenyl) -5-methoxy-
1,3,4-oxadiazol-2 (3H) -one (generic name methoxadiazone, trade name Elemic: manufactured by Sumitomo Chemical Co., Ltd., hereinafter referred to as "methoxadiazone"), and as a pest to be controlled. Is, for example, the housefly,
Sanitary pests such as mosquitoes, cockroaches, fleas, bedbugs, house dust mites and dust mites, and agricultural pests such as aphids, planthoppers and spider mites. If the above-mentioned active ingredient is a target pest, it is not limited to the exemplified range.

[0010]

BEST MODE FOR CARRYING OUT THE INVENTION In the fumigant composition for controlling pests of the present invention, the concentration of methoxadiazone fumigated in air is 45 mg / m ³ or more (about 123 mg / m ² or more when converted per projected area on a plane). As long as they are sensitive to cockroaches, which are particularly problematic, even if they are resistant to pyrethroid compounds, they show a sufficient controlling effect. This active ingredient, methoxadiazone, appears to have a certain effective concentration, because its efficacy is not just proportional to its concentration, but that it becomes effective when it reaches a certain concentration. It was previously unknown that methoxadiazone effectively acts at such a concentration in the present invention, and was not expected.

In this case, it is not necessary to dare to set an upper limit to the concentration of the active ingredient to be fumigated, but in view of economic efficiency and safety to the human body, 70 mg / m ³ or less (per projected area on a plane) 185 mg if converted
/ M ² or less) is preferable. That is, when the above-mentioned effective ingredient concentration is fumigated more than 70 mg / m ³ , the effective ingredient will be present in the air more than necessary, which is not appropriate from the viewpoint of economical efficiency and safety. Since the fumigant is used in an unoccupied enclosed space, its toxicity to the human body does not pose a problem, but it is not preferable to use it in an amount more than necessary. Further, it has not been known so far that the concentration of the above-mentioned active ingredient is 70 mg / m ³ or less, and it has been clarified by the study of the present inventor that the concentration of such a specific range is It can act effectively at concentrations.

When fuming methoxadiazone in the present invention, it is efficient and preferable to fumigate almost all the amount of the active ingredient usually in about 2 minutes. But,
The present invention is not limited to being appropriately adjusted and used depending on the use conditions and the size of the space, as long as the concentration of the active ingredient in the air by fumigation falls within the range of the present invention. In the fumigant composition for controlling pests of the present invention, although there are some differences depending on the fumigation method, since the volatilization rate of methoxadiazone is about 60 to 90%, the amount of methoxadiazone contained in the drug is The amount should take the rate into consideration.
The fumigant composition for controlling pests of the present invention, when used as a fumigant, includes a jetting agent, an ignition method such as a rod agent, a hydrothermal heating type, a chemical reaction method such as an air oxidation heating type, and an electric heating method. However, other schemes can also be used.

The base of the jetting agent is a mixture containing a nitrate or nitrite and a thermal decomposition accelerator (for example, an alkaline earth metal salt, an alkali metal salt) as a main base, a guanidine salt and a thermal decomposition accelerator. An example is one in which a mixture of agents (for example, dichromate and chromate) is used as the main base nitrocellulose compound. The base of the rod agent is a mixture of a combustion agent (eg ethyl cellulose, nitrocellulose), an anti-inflammatory agent (eg melanin, wheat starch), a bulking agent (eg diatomaceous earth) and an excipient as a main base. Is mentioned. The base of the rod agent is a combustion agent (eg, ethyl cellulose, nitrocellulose),
Those based on a mixture of an anti-inflammatory agent (for example, melanin, wheat starch), a bulking agent (for example, diatomaceous earth) and an excipient can be mentioned. As the evaporation aid, any of various ordinary organic foaming agents which are thermally decomposed to mainly generate nitrogen gas can be used, but those having a foaming temperature of 300 ° C. or lower are preferable. Representative organic foaming agents are shown in Table 1 below.

[0014]

[Table 1]

The above-mentioned organic foaming agent is an additive such as Cd-stearate, Ca-stearate, Zn-stearate, Zn-octate, ZnO, Sn-malate, urea, chrome yellow, carbon black or the like which is usually added to these. Can be used in combination to lower the foaming temperature. In the present invention, the mixing ratio of the foaming agent to the insecticidal agent is preferably about 1/2 times the weight of the foaming agent with respect to the so-called insecticidal effect of the obtained pesticide. The effective volatilization rate of the insecticide increases as the mixing ratio of the foaming agent increases, but the effect does not improve even if it increases too much. It is usually preferable to use the foaming agent in an amount of about 1/2 to 30 times the weight of the insecticide. Further, the mixed form of the insecticide and the foaming agent is not particularly limited, considering the workability and the ease of production and use of the resulting pesticide, suitable granules, lumps, pellets, pastes, tablets. In addition, it is preferable to coat these dosage forms with various coating agents and enclose them in a hot-melt resin bag or the like, and various binders, solvents and the like can be used depending on the respective usage forms.

Examples of the exothermic substance are substances such as calcium oxide, magnesium chloride, aluminum chloride, calcium chloride, iron chloride, etc., which generate an exothermic reaction only by adding water. Using this exothermic substance as a heat source, the mixture of various forms obtained by mixing the above-mentioned insecticide and foaming agent and, if necessary, suitable additives, is heated indirectly without burning the mixture. The foaming agent is pyrolyzed. As the air-oxidation exothermic type base, a transpiration agent consisting of the above-mentioned inducing foaming agent and a sulfide of an alkali metal, a polysulfide, a hydrosulfide or a hydrous salt or the like, a catalyst substance (for example, carbon black, activated carbon, Charcoal, coke, asphalt)
In addition, those containing a combination of a filler (for example, a natural fiber, a synthetic fiber, a synthetic resin foam) as a main base are included. As a method utilizing the oxidation reaction of metal sulfide, a method of bringing a mixture of sodium sulfide and iron carbide into contact with oxygen can be exemplified.

Further, as a heat source for thermally decomposing the foaming agent in the mixture of various forms obtained by mixing the above-mentioned insecticide and foaming agent and, if necessary, suitable additives, an electric heat source which generates heat by energization can also be used. For example, a ferrochrome wire, a nichrome wire, a positive temperature coefficient thermistor (PCT), a sheet heater, a heater using a semiconductor, and the like can be exemplified. Among these, the chemical reaction agent type, the electric heating type, and the water heating type are preferable from the viewpoint of safety without using a flame by a match or an igniter. Further, in the fumigant for controlling pests of the present invention, the active ingredient is volatilized in the air, also means a dosage form to evaporate, fumigants such as the above, fumigants, in addition to the vaporizer contents It may be in a form of ejecting (a whole amount of the content is injected into the air in a short time), for example, a so-called mass-injection type aerosol agent.

As its base, solvents (kerosene, alcohol solvents such as methanol and ethanol, amphipathic substances such as glycol and ether, water), propellants (liquefied petroleum gas, dimethyl ether, carbon dioxide, CFCs) are used. A mixture containing a mixture as a main base may be used, and at this time, a special valve such as a mass injection valve may be attached to adjust the ejection amount. In the fumigant composition for controlling pests of the present invention, if it does not hinder in achieving the intended effect of the present invention, for example, if volatilization or diffusion of the active ingredient is not hindered, then There is no limitation to properly blend other ingredients such as fragrances and germicides.

According to the studies by the present inventors, methoxadiazone, which was considered to have a sufficient controlling effect when used in combination with a pyrethroid compound, was administered at 45 mg / m ³ or more,
It is preferable to fumigate in air at a specific concentration of 45 to 70 mg / m ³ to obtain a better control effect than when it is used in combination, and particularly effective against insect pests having pyrethroid resistance. Found out. The detailed principle is not clear, but by fumigating at this concentration, the active ingredient sufficiently acts on the cockroaches living in the shade and the corners of the room, and the pyrethroid resistant It also shows an excellent control effect on the plants due to the difference in the mechanism of action. Furthermore, it was found that methoxadiazone itself does not show repellent action even at the above-mentioned specific concentration, and it does not cause defects such as escape of cockroaches from the treatment space, which is seen in pyrethroid compounds. Conventionally, in the presence of an object that serves as a shelter, when methoxadiazone alone is used against cockroaches, it shows resistance, and its sensitivity does not seem to be effective. In the present invention, it has been found that the combined use with the pyrethroid compound effectively acts even in the presence of an object serving as a shelter in a specific concentration range.

[0020]

The present invention will be specifically described below with reference to examples. However, the present invention is not limited to only this embodiment. Example 1 a. Biological activity test a-1. Preparation of test preparations Insecticide granules consisting of active ingredient (methoxadiazone), starch binder, antioxidant, transpiration aid (azodicarbonamide), transpiration aid additive (zinc oxide), exothermic agent (calcium oxide) ) And a fumigant for controlling harmful insects of the hydrothermal exothermic type prepared by separately storing the granules and the exothermic agent. Table 2 shows the composition of the fumigant for controlling pests. In addition, fumigants a (permethrin as an active ingredient, fumigation concentration of 28 mg / m ³ and methoxadiazone, fumigation concentration of 22 mg / m ³ , total active ingredient concentration of 50 mg / m ³ ), b (permethrin as an active ingredient) were compared. A fumigation concentration of 8.5 mg / m ³ and dichlorphos,
Fumigation concentration is 34 mg / m ³ , total active ingredient concentration is 50 m
g / m ³ ) was prepared and used for the next test.

[0021]

[Table 2]

A-2. Test method The above fumigant is shown in FIG. 1 at 35 m ³ (3.6 × 3.6 ×).
2.7 m, the volume of the chamber is equivalent to a Japanese-style room of 8 tatami mats). Further, pyrethroid-resistant cockroaches (30 adults, 20 old larvae, 30 young larvae) were respectively housed in two containers with a shelter, and these were placed on the floor in the chamber 1 shown in FIG. I placed it in two places. A pest control fumigant 2 is placed in the center of the floor in the chamber 1, and the pest control fumigant is fumigated therein so that the concentration of the active ingredient in the space shown in Table 2 becomes a predetermined value. After 2 hours, the two containers were taken out, the cockroaches were placed in another polycup, and knockdown and mortality with time were investigated. The container 3 used here has a shape with an open upper part, and calcium carbonate is applied to the upper part of the surrounding wall to prevent cockroaches from being exposed to the outside, and a shelter 4 is formed inside to form a zigzag cross section. A folded product (cardboard material) having three stacked shapes is placed, and a feed container 5 and a water container 6 are provided inside. After preliminarily breeding it for 1 to 2 nights, the container 3 was put into the chamber 1 and subjected to the test. that time,
Most of the cockroaches are inhabited between the folded pieces of paper inside the shelter 4. The specific installation locations are shown in FIGS. 1 and 2, and the results are shown in Table 3.

[0023]

[Table 3]

A-3. Test Results The fumigant of the present invention has a fumigant concentration of the active ingredient in the air of 4
It showed a remarkable knockdown rate and lethality rate at 5 mg / m ³ or more, and was used as a fumigant for the subject a (permethrin as an active ingredient, fumigation concentration is 28 mg / m ³ and methoxadiazone 22 mg / m ³ ), b (as an active ingredient). Permethrin, fumigation concentration of 8.5 mg / m ³ and dichlorphos 3
4 mg / m ³ ). In particular, in the case of the fumigant of the present invention, the knockdown rate and the lethality rate show values of 100% or close to 100%, respectively, and being 100% or close to this means that insects are completely or almost completely killed. On the other hand, when the numerical value is lower than this, such as the target b or the target a, that is, if some living insects are present, a product with excellent reproductive ability such as a cockroach, Since the population density is restored within a short period of time, the effect is not only recognized as the difference in the numerical value, but the difference in the actual effect is more significant, so it must be evaluated at that point. . The above-mentioned effects were remarkably observed even in a container with a shelter in which the control agent was hard to reach due to diffusion, and it was confirmed that the effect is also effective against cockroaches inhabiting shade and room corners.

[0025]

The fumigant composition for controlling pests according to the present invention has an air content of 45 mg / m ³ or more, preferably 45 to 70 mg.
By containing methoxadiazone in an amount capable of being fumigated so that it is present at a specific concentration of / m ³ , methoxadiazone can be fumigated so that it is present in the air at a specific concentration when used, thereby providing a pyrethroid insecticide. Without concomitant use, there is no repellency due to this concentration,
An excellent control effect can be obtained even against pyrethroid-resistant pests. In addition, since it is possible to obtain a sufficient effect by itself, it is economical and safe.

[Brief description of the drawings]

FIG. 1 is a schematic view of a chamber in which a container containing cockroaches is installed in an embodiment of the present invention.

FIG. 2 is an enlarged view showing a container accommodating the cockroaches used in FIG. 1, a is a plan view thereof, and b is the a
A sectional view taken along line AA ′ of FIG.

[Explanation of symbols]

 1 Chamber 2 Fumigant 3 Container 4 Shelter 5 Feed Container 6 Water Container 7 Cockroach

Claims (2)

[Claims] 1. An amount of 3- (2-methoxyphenyl) -5-methoxy-1,3,4-oxadiazole-which can be present in air by fumigation at 45 mg / m ³ or more.
A fumigant composition for controlling pests, which comprises 2 (3H) -one as an active ingredient. 2. 45 to 70 mg / m in air by fumigation
³ Pest control characterized by containing as an active ingredient 3- (2-methoxyphenyl) -5-methoxy-1,3,4-oxadiazol-2 (3H) -one in an amount that can be present Fumigant composition for use.