JPH09135879A - Ophthalmic medicine administration implement - Google Patents

Abstract

PROBLEM TO BE SOLVED: To surely and precisely apply a predetermined quantity of a medicine and to prevent a human hand from touching the medicine by forming a medicine storage part for storing therein the medicine in the one opening side of a cylindrical casing, and by providing a squeeze-out mechanism for squeezing out the medicine by a predetermined volume at each time, on the other opening side. SOLUTION: A part in the vicinity of an one opening side near to a medicine storage part 30 is tapered toward its tip end so as to depict a gentle curve, and a squeeze-out mechanism 55 is provided the other opening side. Further, a cap 105 and a clip part 120 for unusing are provided, and a scale for squeezing out a predetermined quantity of a medicine 45 is provided to each of a rotary grip 65 and the grip 65 side of the cylindrical casing 15. Upon use, the grip 65 is turned so as to align the scale on the cylindrical casing 15 side with the scale on the grip 65. When the grip 65 is turned, a protrusion 80 in the squeeze- out mechanisms 55 is turned so that a medicine squeeze-out part 90 is moved toward the side opposite to the grip 65, and accordingly, the medicine 45 stored in the cylindrical casing 15 is squeezed out by a predetermined quantity under pressure.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to an ophthalmic drug administration device.

[0002]

2. Description of the Related Art Conventionally, an ointment containing a calcium salt is known as a therapeutic agent for dry eye (US Pat. No. 5,290,572). In addition, as a method of continuously administering a drug to the cornea for the treatment of dry eye, the ointment is applied to the side of the lower eyelid of the edge of the eye by hand, and a small amount of the drug is continuously applied to the eye by blinking. A method of incorporating it has been disclosed (US Pat. No. 5,366,739).

According to this treatment method, the medicine can be naturally taken into the eye by blinking, so that continuous treatment is necessary, for example, from the condition where the eye is always dry such as dry eye. In the case of protecting the eyes, a treatment method in which calcium, which is one of the components of tears, is continuously administered to the eyes with an ointment is more effective than a treatment to temporarily relieve the dry symptoms with eye drops. It was

[0004]

The conventional ointment is usually
I used it by applying an appropriate amount from the container to the edge of the eye by hand.
However, there are considerable individual differences in determining how much ointment should be used, and it is difficult for the patients who use it to determine the appropriate amount. Or the effect was reduced because it was too small.

Further, when the ointment is directly applied by hand, there is a possibility that bacteria attached to the hand may adhere to the ointment and be taken into the eye together with the ointment.

[0006] Therefore, an object of the present invention is to provide an ophthalmic drug administration device which can be used conveniently and hygienically without the conventional problems.

[0007]

In order to achieve the above-mentioned object, an ophthalmic drug administration device of the present invention comprises a cylindrical case 15,2.
An extruding mechanism that has medicine storage parts 30, 35, 40 for storing the medicines 45, 48, 50 on one opening side of 0, 25 and pushes out the stored medicines 45, 48, 50 by a fixed amount on the other opening side. The parts 55, 60 and 63 are provided to prevent a certain amount of reliable application and touch.

Then, the medicine container 30 of the cylindrical case 15
The side opening is tapered toward the tip so as to draw a gentle curve, and the rotary grip 65 is provided on the other opening side.
Then, the pushing-out mechanism 55 can be provided, which includes a projecting portion 80 in the shape of a rod integrally provided inside the tubular case, and a drug pushing-out portion 90 provided so as to be screwed with the rod of the projecting portion.

Further, the vicinity of the opening of the cylindrical case 20 on the side of the medicine storage portion 35 is tapered toward the tip so as to draw a gentle curve, and the groove 27 provided in a corrugated shape on the side of the cylindrical case on the other opening side. From a lever 70 that has a stopper 68 that moves back and forth inside, and a drug push-out portion 95 that pushes the drug out of the tubular case by connecting it to the drug storage portion through the inside of the bellows-shaped tubular case integrally formed with the lever. It is also possible to provide an extruding mechanism section 60.

[0010] And, having a protrusion 130 on the outside, the drug 5
0, a cutout 125 and a grip 75 that slidably engage with the protrusion 130.
And a spiral groove 2 for accommodating the inner case 85 and having the protrusion 130 of the medicine accommodating portion 40 fitted therein.
Extrusion mechanism portion 63 including a cylindrical case 25 having 8
It is also possible to provide an ophthalmic drug administration tool in which the vicinity of the opening side of the middle case 85 and the vicinity of the opening side of the tubular case 25 are tapered toward the distal end so as to draw a gentle curve.

Further, in the case of dry eye treatment, a cylindrical case 15, 20, 15 for containing a dry eye treatment drug in which a part of components contained in normal tears is mixed in a carrier.
It is also possible to use the ophthalmic drug administration tools 1, 5, 10 provided with push-out mechanism parts 55, 60, 63 for pushing out the drugs 45, 48, 50 by a fixed amount on one opening side.

Further, there is provided a drug storage portion 30, 35, 40 for storing the drug on one opening side of the cylindrical case 15, 20, 25 for storing the dry eye treatment drug in which at least calcium carbonate is mixed in a carrier, On the other hand, a push-out mechanism section 55 that pushes out the stored medicine to the opening side by a fixed amount,
The ophthalmic drug administration tools 1, 5, 10 provided with 60, 63 are provided.

Further, the ophthalmic drug administration tools 1, 5, 10
It is effective to store a drug for treating dry eye containing approximately 10% of calcium carbonate.

Further, pushing mechanism parts 55, 60, 63 for pushing out a certain amount of the drug into one opening side of the cylindrical cases 15, 20, 25 for accommodating the drug for treating dry eye in which calcium carbonate and potassium acetate are mixed in a carrier. May be provided.

Further, it is effective that the carrier used for the drug in the ophthalmic drug administration device is petrolatum.

Further, the ophthalmic drug administration tools 1, 5 and 10 in which the contained drug is 2% to 10% calcium carbonate and 0.4% to 2% potassium acetate mixed in petrolatum can be used.

[0017]

BEST MODE FOR CARRYING OUT THE INVENTION Embodiments of the present invention will be described with reference to the drawings.

FIG. 1 is a longitudinal sectional view of an ophthalmic drug administration device 1 showing an embodiment of the present invention.

The ophthalmic drug administration device shown in FIG.
The vicinity of the 0-side opening is tapered toward the tip so as to draw a gentle curve, while the rotary grip 6 is provided on the other side of the opening.
5, a push-out mechanism portion 55 including a screw-rod-shaped protrusion 80 integrally provided inside the tubular case 15 and a drug push-out portion 90 provided so as to be screwed with the screw rod of the protrusion, Cap 105 and clip portion 12 when not in use
It is equipped with 0.

The rotary grip 65 and the rotary grip side of the cylindrical case 15 are provided with scales for dispensing a certain amount of medicine. The ointment used as the chemical agent 45 inside has a viscosity such that it can be easily deformed when extruded by the extrusion mechanism and can maintain its shape when extruded to the outside of the cylindrical case. Here, petrolatum or glycerol (15-20%) or mineral oil or wax is used as a carrier, and a dry eye medicine 45 is prepared by mixing 10% calcium carbonate or 10% calcium carbonate with 2% potassium acetate.

In use, the grip 65 is attached to the cylindrical case 1.
Rotate the scale so that the scale on the 5 side and the scale on the grip are aligned. When the grip portion 65 is turned, the pushing mechanism portion 55
Of the protrusion 80 of the rotating and screwed medicine pushing portion 90
Moves toward the side opposite to the grip 65, and the pressure causes the medicine 45 held in the cylindrical case 15 to move to the cylindrical case 1.
Push a fixed amount out of 5. Then, the dry eye drug administration device 1 is brought to the vicinity of the eye, and the dry eye drug 45 is applied to the edge of the eye on the side surface of the lower eyelid as it is. afterwards,
The dry eye drug 45 applied to the side edge of the lower eyelid by normal blinking is naturally administered to the eye in minute amounts.

When the dry eye drug administration tool 1 is not used, the drug 45 is stored with a cap 105 provided so that the drug 45 does not become dusty. Further, as shown in FIG. 1, a clip 120 is provided on the side of the cylindrical case on the grip 65 side.
It is more convenient and convenient to keep it in your pocket and carry it in the pocket of your clothes or the edge of your bag. Furthermore, if at least the cylindrical case 15 of the ophthalmic drug administration device 1 is made of a transparent member, the remaining amount inside can be easily understood, and the determination of the end time can be easily predicted, which is convenient.

FIG. 2 shows an ophthalmic drug administration device 5 according to an embodiment of the present invention. In the figure, (a) is a vertical sectional view of the whole image, (b) is a partially enlarged vertical sectional view of the vicinity of the lever,
(C) is a cross-sectional view of the lever portion.

In the ophthalmic drug administration device 5 of FIG. 2, the vicinity of the drug storage portion 35 for accommodating the drug 48 of the cylindrical case 20 is tapered toward the tip so as to draw a gentle curve, and the other opening side. The corrugated surface 69 and the groove 2 on the side of the cylindrical case
7 and a stopper 68 that contacts the corrugated surface inside, and a lever 70 that moves back and forth in the groove 27, and a bellows-shaped groove 27 formed integrally with the lever and the inside of the cylindrical case. A push-out mechanism unit 60 including a drug pushing-out unit 95 that pushes the drug 48 to the outside of the cylindrical case in connection with the through drug storage unit 35 is provided, and a cap 110 for when not in use
It is provided with. As the medicine used here, the medicine 48 having the same viscosity as that of the embodiment shown in FIG. 1 is used.

In use, the lever 70 is moved along the corrugated surface 69. Since the lever is a push-out mechanism unit that is integrated with the bellows-shaped drug push-out unit 95, it slides in the groove 27 provided in the tubular case from the side surface of the tubular case.
The medicine 48 held in the medicine container 35 can be pushed out of the cylindrical case 20. Since the pushing amount is a fixed amount for each peak of the corrugated surface 69, a fixed amount can be adjusted depending on how many peaks of the corrugated surface are moved. Further, since the stopper 68 is provided in the lever, the lever is fixed at each crest of the corrugated surface, so it is not necessary to return the lever once lowered. Further, when the lever is lowered to the lowest position, the medicine 48 inside the cylindrical case is completely ejected, so that the remaining amount of the medicine inside the cylindrical case is reduced to the lever 70.
Depending on the position of, it is easy to see at a glance. Further, FIG.
At least the cylindrical case 20 can be made of a transparent member as in the above embodiment, and it is possible to easily know the remaining amount inside by matching the position of the lever. When not in use, the cap 110 provided as in FIG. 1 is used for hygienic storage, and a clip is provided on the side of the cylindrical case that faces the lever on the side opposite to the cap. It can be stored on the edge of the garment and is convenient to carry.

FIG. 3 shows a perspective view of an ophthalmic drug administration device 10 which is an embodiment of the present invention. 4 is a side view of each component of the ophthalmic drug administration device 10 shown in FIG.

The ophthalmic drug administration device shown in FIGS. 3 and 4 is provided integrally with a tubular case 25 having a spiral groove 28 in the inner diameter, a rotary grip 75 on the one opening side, and a tubular case inside the tubular case 25. A tubular middle case 85 having a cutout 125 for vertically moving the medicine to be held therein, and a rod-shaped medicine 50 inside the tubular middle case, and a cutout and a tube of the tubular middle case. The push-out mechanism portion 63 is provided with a drug push-out portion 100 having a protrusion 130 that goes back and forth in the spiral groove 28 of the cylindrical case on the lower side surface, and is provided with a cap 115 for when not in use. In the present embodiment, the medicine 50 inside the cylindrical case is an ointment having a viscosity sufficient to maintain a rod-like shape.

At the time of use, the grip 75 is scaled 135
Cut out the protruding part 85 of the grip
25 and the protrusion 130 of the drug pushing-out portion 100 holding the drug on the spiral groove 28 provided inside the tubular case 25 on the outer side thereof, an appropriate amount of the drug as shown in FIG. Is placed above the cylindrical case 25. Then, it is applied to the edges of the eyes in the same manner as in the embodiment shown in FIGS.

The agents 45, 48 and 50 used in the ophthalmic drug administration tools 1, 5 and 10 of the present invention are prepared by adjusting the viscosity of the ointment according to the therapeutic and disease prevention applications as described in the above examples. be able to.

Further, petrolatum or glycerol (15-20%) or mineral oil or wax can be used as a carrier, and electrolytes such as calcium and potassium are mixed with these carriers to prepare ophthalmic drug administration tools 1, 5 It can also be used as 10.

Further, SOD, EGF,
By mixing KGF, growth factors such as vitamins, proteins, and vitamins, the administration tools 1, 5, and 10 of the present invention can be used as a treatment for other diseases including ophthalmology and a tool for preventing those diseases. In particular, in the treatment of dry eye, it is effective to administer 10% calcium carbonate alone to petrolatum or to use a drug in which 10% calcium carbonate and 2% potassium acetate are mixed.

There are various administration methods of calcium,
Since calcium carbonate is transparent and neither acid nor alkali,
Easy to use. For example, calcium chloride has a strong acidity and is not suitable as a drug. Further, since physiological calcium in tears exists as calcium carbonate, calcium carbonate is also suitable from this aspect. Further, various investigations regarding the concentration revealed that 25% had strong irritation and 2% had insufficient effect. When it is about 10%, calcium can be sufficiently supplied, and it is comfortable with little irritation. Furthermore, although it is well mixed with petrolatum, which is a carrier, and has a slight cloudiness, it can maintain a certain degree of transparency.

At least the cylindrical cases 15 and 2
If 0 and 25 are made of transparent members, the remaining amount of the drug inside can be known and the judgment at the end can be easily made.

[0034]

Since the present invention is configured as described above, it has the following effects.

Scale 135 or stopper 68 when used
As a result, a fixed amount is used and used, so it is easy to determine an appropriate amount and it can be handled easily.

Further, since it is not necessary to pick up the ointment by hand, it is hygienic, and since it is possible to keep the hands clean, it can be used more speedily than before and is convenient.

[Brief description of the drawings]

FIG. 1 is a longitudinal sectional view of an ophthalmic drug administration device according to an embodiment of the present invention.

FIG. 2 is an ophthalmic drug administration device according to one embodiment of the present invention, in which (a) is a vertical cross-sectional view of the overall image, (b) is a partially enlarged vertical cross-sectional view of the vicinity of the lever, and (c) is the lever portion. FIG.

FIG. 3 shows a perspective view of an ophthalmic drug administration device according to an embodiment of the present invention.

4 shows a vertical cross-sectional view of each component of the embodiment shown in FIG.

[Explanation of symbols]

1,5,10 Ophthalmic drug administration device, 15, 20, 25
Cylindrical case, 27, 28 groove, 30, 35, 40 medicine container, 45, 48, 50 medicine, 55, 60, 63
Extrusion mechanism part, 65, 75 grip, 90, 95,
100 drug extruding part, 105, 110, 115 cap, 68 stopper, 69 corrugated surface, 70 lever, 80 protruding part, 85 middle case, 120 clip part, 125 cutout, 130 protrusion, 135 scale.

Claims (10)

[Claims] 1. A medicine container 30 for accommodating medicines 45, 48, 50 in one opening side of the cylindrical cases 15, 20, 25.
35 and 40, and the stored medicine 4 on the other opening side
Extrusion mechanism 5 for extruding 5, 48, 50 by a fixed amount
Ophthalmic drug administration tools 1, 5, 1 provided with 5, 60, 63
0. 2. The cylindrical case 15 has a taper portion near the opening on the side of the storage portion 30 for storing the medicine 45, which is tapered toward the tip, and a rotary grip 65 on the other opening side. The push-out mechanism section 55 is provided, which is provided with a rod-shaped projecting portion 80 integrally provided inside the tubular case, and a drug pushing-out portion 90 provided so as to be screwed with the screw rod of the projecting portion. Ophthalmic drug administration device 1. 3. The cylindrical case 20 is tapered toward the tip in the vicinity of an opening on the side of the medicine storing portion 35 for accommodating the medicine 48 so as to draw a gentle curve, and on the other opening side, a corrugated shape is formed on the side surface of the cylindrical case. This corrugated surface 6 has a surface 69 and a groove 27.
A lever 70 having a stopper 68 that abuts against the groove 27, and a lever 70 that moves back and forth in the groove 27 and a bellows-shaped integrally formed with the lever that passes through the groove 27 and the inside of the cylindrical case.
The ophthalmic drug administration device 5 according to claim 1, further comprising a push-out mechanism unit 60 that is connected to the push-out unit 5 and pushes out the drug to the outside of the cylindrical case. 4. A middle case 85 having a protrusion 130 on the outside, a medicine storage portion 40 for accommodating a medicine 50, a cutout 125 slidably fitted to the protrusion 130, and a grip 75, and a middle case. A push-out mechanism portion 63 is provided which is configured to house 85 and a cylindrical case 25 having a spiral groove 28 into which the protrusion 130 of the medicine storage portion 40 is fitted. The pushing mechanism portion 63 is provided near the opening side of the middle case 85 and the cylindrical case. Two
The ophthalmic drug administration device 10 according to claim 1, wherein the vicinity of the opening side of 5 is tapered toward the tip so as to draw a gentle curve. 5. A medicine container 30 for accommodating a medicine in one opening side of a cylindrical case 15, 20, 25 for accommodating a medicine for dry eye treatment in which a part of components contained in normal tears is mixed in a carrier. An ophthalmic drug administration device having 35, 40 and extrusion mechanism parts 55, 60, 63 that push out the stored drugs 45, 48, 50 by a fixed amount on the other opening side. 6. A cylindrical case 1 for accommodating a drug for treating dry eye in which at least calcium carbonate is mixed in a carrier.
5, 20 and 25 have drug storage parts 30, 35 and 40 for storing a drug on one opening side, and push-out mechanism parts 55 and 60 for pushing out the stored drug by a fixed amount on the other opening side.
The ophthalmic drug administration device 1, 5 according to claim 5, which is provided with 63.
10. 7. The ophthalmic drug administration device 1, 5, 10 according to claim 6, which contains a drug for treating dry eye having a calcium carbonate content of about 10%. 8. Extrusion mechanism parts 55, 60 for extruding a certain amount of a drug into one opening side of a cylindrical case 15, 20, 25 for accommodating a drug for treating dry eye in which at least calcium carbonate and potassium acetate are mixed in a carrier. The ophthalmic administration device 1, 5, 10 according to claim 5, which is provided with 63. 9. The ophthalmic drug administration device 1, 5, 10 according to claim 6, 7 or 8, wherein the carrier is petrolatum. 10. The ophthalmic agent according to claim 8, wherein the stored medicines 45, 48 and 50 are obtained by mixing 2% to 10% of calcium carbonate and 0.4% to 2% of potassium acetate into petrolatum. Administration tools 1, 5, 10.