JPH09108204A - Measurement position reproduction method, measurement position reproduction device, and body fluid component concentration measuring device using it - Google Patents

Abstract

PROBLEM TO BE SOLVED: To measure the body fluid component concentration by projecting the measuring light on the sole of the foot part of a person to be measured in the superior reproductivity so as to provide fixed measuring conditions all the time. SOLUTION: A measuring light is projected on the foot part of a person to be measured mounted on an subject mount 2 of a spectral analysis device 3, the intensity of the reflected or transmitted light is operated by an operation control device 4, and output on a CRT display 6 and a printer 7. In the first measurement, a measurement position of the sole of the foot part is selected and the position of the foot part is registered as the position of a foot part positioning member 41 in a storage device 5 as well as the contact pressure of a foot arch contact plate 57 with the arch of the foot, the weight, and information specifying the person to be measured. In and after the second measurement, the position of the foot part positioning member 41 is reproduced based on the information stored in the storage device 5 so that the person be be measured positions the foot part on the subject mount 2 and at the same time the foot arch contact plate 57 contacts with the arch of the foot part by the registered contact pressure.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention is obtained by detecting transmitted or reflected light obtained by projecting measurement light at a predetermined measurement position on the back of the foot of a person to be measured. When measuring the concentration of a specific component in the body fluid of the person to be measured based on the detected light, a measurement position reproducing method and measurement in which the predetermined measurement position is reproduced by reproducing the foot of the person to be measured at a pre-registered position The present invention relates to a position reproducing device and a body fluid component concentration measuring device using the position reproducing device.

[0002]

2. Description of the Related Art In recent years, in the field of clinical examinations, non-invasive monitors for measuring the concentration of specific components in urine, blood or a living body by non-invasive method have been studied. When measuring the concentration of a specific component in a living body using this type of non-invasive monitor, when measuring using the light that has passed through the tissue of the living body, and when using the light reflected from the tissue of the living body There is. In a scattering system such as biological tissue, unless the effective optical path length due to scattering and the amount of light incident on the measurement target are determined,
It is not possible to determine the absolute value of the absorbance and therefore the concentration of the light absorbing substance. Further, the amount of incident light on the measurement target changes due to direct reflection from the surface of the measurement target due to the difference in the surface condition and the light incident angle.
For this reason, when measuring the concentration of a specific component in a living body using a non-invasive monitor, it is necessary to project and receive light at the same position and under the same conditions for each measurement object each time.

[0003]

By the way, in measuring non-invasively the concentration of a specific component in a living body, factors affecting the reproducibility of the measurement include, in addition to environmental conditions, Color, shape, physiological state change, combination of physiological functions shown as characteristic difference or site difference in the measured object, ・ Setting state by repositioning the measured object at each measurement, which is shown as an error in the measurement method -The change in the contact pressure between the measurement opening and the site to be measured of the measurement part including the light incident part and the light receiving part. Changes in measurement data due to changes in the measurement conditions are shown in FIGS. 11 and 12.

The measurement data of FIG. 11 is obtained as follows. That is, (1) an optical fiber is used to irradiate the measurement site selected first on the palm of the subject, which is a part of the living body, with light to receive reflected light, and measure a reference energy spectrum (A). . (2) The light irradiation position is shifted by 1 mm from the initially selected position, the light is irradiated without changing the irradiation angle, and the energy spectrum (B) is similarly measured. (3) The light irradiation position is further shifted by 1 mm, for convenience, by 2 mm from the position initially selected, and the light is irradiated without changing the irradiation angle, and the energy spectrum (C) is similarly measured. (4) The irradiation position of the light is returned to the initially selected position, the test subject is allowed to drink the aqueous solution for "Torran 75" glucose tolerance test manufactured by Shimizu Pharmaceutical, and the irradiation angle is changed when the blood glucose level of the test subject changes by 15 mg / dl. Is radiated without changing, and the energy spectrum (D) is similarly measured. (5) In the energy spectrum (A) measured in the step (1), the energy spectrum (A),
Dividing (B), (C), and (D) respectively, multiplying the result by 100, respectively, (E) = {(A) /
(A)} × 100, (F) = {(B) / (A)} × 10
0, (G) = {(C) / (A)} × 100, (H) =
It is set to {(D) / (A)} × 100. (6) Then, (E) is subtracted from the above (F) to obtain the result shown in FIG.
Curve h _1, curve h ₂ in FIG. 11 by subtracting the (E) from the (G), obtaining the curve h ₃ of FIG. 11 by subtracting the (H) from (E).

In FIG. 12, the position and the angle of the optical fiber are fixed, and the first selected measurement site of the palm of the subject, which is a part of the living body, is irradiated with light to receive reflected light,
An energy spectrum (A) serving as a reference is measured, and thereafter, in (2) and (3), instead of changing the position of the measurement site selected first, an optical fiber is set to 1 mm or 2 mm with respect to the measurement site. The energy spectrum when pressed by pressing 3 mm and 4 mm is measured. Then, the blood glucose level of the subject due to drinking the aqueous solution for glucose tolerance test according to (4) above was 15 mg.
The energy spectrum at the time when / dl is changed is measured, and the curves h ₂₁ , h ₂₂ , h ₂₃ , and h ₂₄ of FIG. 12 are obtained by the same calculation as in (5) and (6) above.

In FIGS. 11 and 12, the absorption wavelength of glucose is 1667 nm (6000 cm ^-1 ).
Blood sugar level of the glucose tolerance test 15mg
The energy spectrum is about 2.75 with respect to the change of / dl.
%, The energy spectrum changes by about 4.88% when the measurement site moves about 1 mm, and changes by about 2.89% when the pressure is increased by 1 mm of the optical fiber length. When actually measuring glucose in vivo, 1 mg /
Since a resolution of dl is required, it is necessary to measure a change of 0.18% when converted. Therefore, about 0.04 mm is required for the position of the measured portion and 0.06 mm for the optical fiber length is required for the reproducibility.

An object of the present invention is to provide a measurement position reproducing method for projecting the measurement light with good reproducibility onto a measurement site set on the back of the foot of the person to be measured in order to always obtain a constant measurement condition. .

Another object of the present invention is to provide a measurement position reproducing device which reproduces a constant measurement condition by projecting measurement light onto a measurement site set on the back of a person's foot with high reproduction accuracy. It is to be.

Still another object of the present invention is to provide a body fluid component concentration measuring apparatus capable of obtaining highly reliable measurement data with little variation in data for each measurement.

Still another object of the present invention is to provide a body fluid component concentration measuring device for correcting the body fluid component concentration measured by the body weight of a subject who measures the concentration of a specific component of body fluid.

Still another object of the present invention is to measure the body fluid component concentration measured by the contact pressure of a member which is in contact with the sole of the foot of the person to be measured for measuring the specific component concentration of the body fluid and projects the measurement light. An object of the present invention is to provide a body fluid component concentration measuring device for correction.

[0012]

In order to achieve the above object, the invention according to claim 1 projects measuring light on the back of the foot of the person to be measured, and transmits or reflects from the foot of the person to be measured. When measuring the specific component concentration of the body fluid of the person to be measured based on the detected light obtained, the measurement position reproduction method in which the measurement light is made incident on a predetermined measurement position which is preselected and registered. That is, when registering the measurement position, the position of the specific part of the foot of the measurement subject is registered, and when reproducing the measurement position, the specific part of the foot of the measurement subject is set to the position at the time of registration. It is characterized by positioning.

[0013] The invention according to claim 2 is based on claim 1.
In the invention described in (3), the specific part of the foot of the subject is the heel and the ankle.

Further, the invention according to claim 3 is characterized in that, in the invention according to claim 1 or 2, information for specifying a person to be measured for measuring a specific component concentration of the body fluid is registered together with the measurement position. And

Furthermore, the invention according to claim 4 is the invention according to any one of claims 1 to 3, characterized in that the measurement position is set to the arch of the foot of the subject.

The invention according to claim 5 is characterized in that, in the invention according to any one of claims 1 to 4, the concentration of the specific component is a glucose concentration.

Further, the invention according to claim 6 projects the measurement light from the projection optical system to the back of the foot of the person to be measured, and detects the light transmitted or reflected from the foot of the person to be measured,
A measurement position reproducing device for making the measurement light incident on a predetermined measurement position selected in advance when measuring the concentration of a specific component of a body fluid of a measurement subject based on the obtained detection light, The object table means for placing the foot of the person to be measured, the foot part positioning means for positioning the foot part of the person to be measured by the specific portion on the object table means, and the foot part positioning means described above. Position adjusting means for adjusting the position on the object table means, position registering means for registering the position information of the foot positioning means adjusted by the position adjusting means, and the position stored in the position registering means Arithmetic control means for controlling the position adjusting means based on information to adjust the position of the foot positioning means.

Further, the invention according to claim 7 is the invention according to claim 6, wherein the object stage means supports the object stage means so as to be two-dimensionally movable relative to the projection optical system. It is characterized in that it is supported on a support mechanism.

Further, the invention according to claim 8 is the invention according to claim 6 or 7, wherein the foot positioning means is a heel contact plate for contacting the heel and ankle of the foot of the subject, respectively. It is characterized by comprising an ankle contact plate.

Further, the invention according to claim 9 is the invention according to any one of claims 6 to 8, wherein the position registration means measures the concentration of a specific component of the body fluid together with the measurement position. Is stored.

Furthermore, the invention according to claim 10 is
The invention according to any one of claims 6 to 9 is characterized in that the measurement position is set on the arch of the foot of the subject.

Furthermore, the invention according to claim 11 is
In the invention according to any one of claims 6 to 10,
The specific component concentration is a glucose concentration.

Furthermore, the invention according to claim 12 is
In the invention according to any one of claims 6 to 11,
The arithmetic and control unit is a personal computer.

Furthermore, the invention according to claim 13 is
The measurement light is projected to a predetermined measurement position on the back of the foot of the person to be measured, the light transmitted or reflected from the foot of the person to be measured is detected, and the object to be measured is detected based on the obtained detection light. A body fluid component concentration measuring device for measuring a concentration of a specific component of a body fluid of a measurer, comprising an object stage means on which the foot of the person to be measured is placed, and an object to be measured of the person to be measured on the object stage means. Foot part positioning means for positioning the foot part by the specific part, position adjusting means for adjusting the position of the foot part positioning means on the object table means, and the foot part positioning adjusted by the position adjusting means. Position registration means for registering the position information of the means, projection optical system means for projecting the measurement light to the measurement position, and light reception for receiving the light that the projected measurement light transmits or reflects on the foot of the person to be measured. Optical system means and light receiving by the light receiving optical system means The detected light intensity detecting means for detecting the intensity of the detected light transmitted or reflected from the foot of the measured subject, and the position adjusting means is controlled based on the position information stored in the position registering means. And adjusting the position of the foot-positioning means and calculating the specific component concentration in the body fluid of the measurement subject based on the intensity of the detected light, and outputting the calculated specific component concentration And output means.

Furthermore, the invention according to claim 14 is
According to a thirteenth aspect of the present invention, the object table means is supported on an object table support mechanism that supports the object table means so as to be movable two-dimensionally relative to the projection optical system.

Furthermore, the invention according to claim 15 is
The invention according to claim 13 or 14 is characterized in that the foot positioning means comprises a heel contact plate and a heel contact plate which respectively contact the heel and heel of the foot of the subject.

Further, the invention according to claim 16 is
The invention according to any one of claims 13 to 15 is characterized in that a weight sensor is provided, and the object table is supported on the weight sensor.

Furthermore, the invention according to claim 17 is
The invention according to claim 16 is characterized in that the concentration of the specific component in the body fluid of the measurement subject calculated by the calculation control means is corrected based on the weight output from the weight sensor.

Further, the invention according to claim 18 is
The invention according to any one of claims 13 to 17, wherein an arch contact member that abuts on the arch of the foot of the person to be measured and projects the measurement light emitted from the projection optical system means onto the arch, An elevating mechanism for elevating the arch contact member in a direction perpendicular to the object table is provided.

Furthermore, the invention according to claim 19 is
The invention according to any one of claims 13 to 15, wherein the elevating mechanism includes a contact pressure detection sensor that detects a contact pressure of the arch contact member on the arch of the foot of the subject. It is characterized by

Furthermore, the invention according to claim 20 is
The invention according to claim 19, wherein the concentration of the specific component in the body fluid of the measurement subject calculated by the calculation control means is corrected based on the contact pressure of the contact member output from the contact pressure detection sensor. Is characterized by.

Furthermore, the invention according to claim 21 is
The invention according to any one of claims 13 to 20 is characterized in that the projection optical system means and the light receiving optical system means are constituted by optical fibers.

Furthermore, the invention according to claim 22 is
The invention according to any one of claims 13 to 20 is characterized in that the projection optical system means and the light receiving optical system means are constituted by integrating spheres.

Furthermore, the invention according to claim 23 is
The invention according to any one of claims 13 to 22 is characterized in that the position registration means stores, together with the measurement position, information for specifying a person to be measured who measures the concentration of a specific component of the body fluid.

Furthermore, the invention according to claim 24 is
In the invention according to any one of claims 13 to 23, the specific component concentration is a glucose concentration.

Furthermore, the invention according to claim 25 is
In the invention according to any one of claims 13 to 24, the arithmetic and control unit is a personal computer.

[0037]

BEST MODE FOR CARRYING OUT THE INVENTION Embodiments of the present invention will be described below with reference to the accompanying drawings.

(Embodiment 1) FIG. 1 and FIG. 2 show the system configuration of one embodiment of a body fluid component concentration measuring apparatus equipped with a measuring position reproducing apparatus according to the present invention. The body fluid component concentration measuring device 1 detects a spectral intensity signal of the reflected light of the measuring light projected on the sole of the person to be measured, and detects the glucose concentration based on the spectral intensity signal. The body fluid component concentration measuring apparatus 1 detects the glucose concentration by performing a calculation process on the spectroscopic analysis device 3 provided with the object table 2 on which the person to be measured is placed and the spectroscopic intensity signal output from the spectroscopic analysis device 3. A calculation control device 4 for controlling a mechanical part of the spectroscopic analysis device 3 which will be described later
A storage device 5 of the arithmetic and control unit 4, a CRT display 6 for displaying data output from the arithmetic and control unit 4, and a printer 7 for obtaining a hard copy of the data output from the arithmetic and control unit 4. ing.

As shown in FIG. 3, the spectroscopic analysis device 3 is provided with an object base 2 and a box-shaped lower housing 8 having a rectangular parallelepiped shape located below the object base 2 and opening upward. The lower housing 8 and the object table 2 are connected to each other by a bellows 9. In the lower housing 8 of the spectroscopic analysis device 3, a light source 11 for measuring light that generates a measuring light having a wavelength absorbed by glucose, a reference light sensor 12 for monitoring the light intensity of the light source 11, and The light receiving sensor 13 is housed. The measuring light emitted from the light source 11 is an arch 16 on the back of the foot 15 of the person to be measured who is on the object table 2 by the measuring light optical fiber 14.
(See arrow A _{1 in} FIG. 3). The light reflected from the foot portion 15 of the person to be measured (see arrow A _{2 in} FIG. 3) is guided to the light receiving sensor 13 by the light receiving optical fiber 17.

In the lower housing 8 of the above-mentioned spectroscopic analysis device 3, a square base plate 18 having a large thickness is also provided on the bottom surface thereof.
Are arranged, and load cells 19 for detecting the weight of the person to be measured are arranged at respective corners on the base plate 18. Each load cell 19 has a cylindrical protrusion 1 on its upper surface.
9a, each of which has the above-described object table 2 on the protrusion 19a.
One end of a coil spring 21 that elastically supports is externally fitted. Each of the coil springs 21 has the other end from each corner of the rectangular reference table 23 of the object support mechanism 22 that supports the object table 2 to the protrusion 19 of the load cell 19.
It is externally fitted to the protrusion 23a protruding toward a.

The inspection table supporting mechanism 22 includes an x-axis direction moving table 24 movably supported on the reference table 23 in the x-axis direction and a y-axis direction on the x-axis direction moving table 24. A y-axis direction moving table 25 movably supported is provided. On the reference table 23, FIG.
As shown in, two x-axis direction guide grooves 2 running in the x-axis direction
6 are formed, and a roller bearing unit 27 (see FIG. 3) fixed to the lower surface of the x-axis direction moving table 24 is guided in these x-axis direction guide grooves 26. As a result, the x-axis direction moving table 24 becomes the reference table 23.
It is supported movably in the x-axis direction above. Also, the above x
Two y-axis direction guide grooves 28 running in the y-axis direction are formed on the axial direction moving table 24, and the inside of these y-axis direction guiding grooves 28 are fixed to the lower surface of the y-axis direction moving table 25. The roller bearing unit 29 is guided. As a result, the y-axis direction moving table 25 becomes the reference table 2
3 is supported so as to be movable in the y-axis direction.

An x-axis movement motor Mx for moving the x-axis direction movement table 24 in the x-axis direction is fixed on the reference table 23. In the x-axis movement motor Mx, a screw shaft 32 attached to an output shaft 31 of the x-axis movement motor Mx is screwed into a bracket 33 connected to the x-axis direction movement table 24. As a result, when the x-axis moving motor Mx rotates, the x-axis direction moving table 24 moves in the x-axis direction according to the rotation amount of the output shaft 31. The amount of movement of the x-axis movement table 24 in the x-axis direction is detected by the x-axis position sensor 34 attached to the x-axis movement motor Mx. The x-axis position sensor 34
Detects the amount of rotation of the output shaft 31 of the x-axis movement motor Mx, and detects the amount of x with respect to the reference table 23 based on the detected amount.
The x-axis direction position of the axial movement table 24 is detected.

On the other hand, on the x-axis direction moving table 24, a y-axis moving motor My for moving the y-axis direction moving table 25 in the y-axis direction is fixed. In the y-axis moving motor My, a screw shaft 36 attached to an output shaft 35 of the y-axis moving motor My is screwed into a bracket 37 connected to the y-axis direction moving table 25. As a result, when the y-axis movement motor My rotates, the output shaft 35
The y-axis direction moving table 25 moves in the y-axis direction according to the amount of rotation. The amount of movement of the y-axis direction moving table 25 in the y-axis direction is detected by the y-axis position sensor 38 attached to the y-axis moving motor My. The y-axis position sensor 38 detects the rotation amount of the output shaft 35 of the y-axis movement motor My, and the reference table 23 is detected based on the detected amount.
The y-axis direction position of the y-axis direction moving table 25 with respect to is detected.

The object table 2 is fixed on the y-axis direction moving table 25. A foot positioning member 4 for positioning the foot portion 15 (see FIG. 3) of the person to be measured on the object table 2 with respect to the object table 2 is provided.
1 is movably supported in the y-axis direction, and the foot part positioning member 41 is moved in the y-axis direction on the object table 2 to move the foot part positioning member 41 on the object table 2. A position adjusting motor 42 for adjusting the position of 41 is arranged. The position adjusting motor 42 is provided with a position detecting sensor 43 for detecting the position of the foot positioning member 41. The foot part positioning member 41 is curved in a substantially arc shape, and as shown in FIG. 5, the foot part 15 of the subject is measured.
Heel contact plate 44 that contacts the outer surface of each heel 15a
And an ankle contact plate 45 that abuts against the ankle 15b on the inside of the foot 15 of the subject.

As shown in FIG. 4, the foot portion positioning member 41 is configured such that the left and right heel contact plates 44 and the left and right heel contact plates 45 are connected to each other by a connecting member 46, and the object to be inspected. A guide member 47 arranged on the table 2 enables movement in the y-axis direction. The position adjusting motor 42 is
The screw shaft 49 attached to the output shaft 48 is screwed into the screw member 50 provided on the coupling member 46 of the foot positioning member 41, and when the position adjusting motor 42 rotates, the output The foot positioning member 41 moves in the y-axis direction according to the amount of rotation of the shaft 48. The amount of movement of the foot positioning member 41 in the y-axis direction is detected by the position detection sensor 43 attached to the position adjustment motor 42. The heel contact plate 44 of the foot positioning member 41 has a heel contact sensor 51 that outputs a contact signal when the heel contact plate 44 contacts the heel 15a of the foot 15 (see FIG. 3). (See) is provided.

Returning to FIG. 3 again, the above reference table 23
The optical fiber holding pipe 5 is inserted into the fitting hole 52 formed in
3 is fitted in a direction perpendicular to the reference table 23 (hereinafter, referred to as z-axis direction) so as to freely move back and forth, and the tip of the arch 16 of the foot portion 15 on the right side of the person to be measured on the object table 2 You can move back and forth toward. The optical fiber holding pipe 53 has a hole 5 formed in the moving table 24 in the x-axis direction.
4, a hole 55 formed in the y-axis direction moving table 25 and a hole 56 formed in the object table 2 are loosely fitted to each other, and the tip thereof is curved upward to the right side of the person to be measured. Arch contact plate 5 that contacts the arch 16 of the foot portion 15
7 is attached. The optical fiber for measuring light 14 and the optical fiber for receiving light 17 are held inside the optical fiber holding pipe 53, and the optical fiber for measuring light 14 is held.
The emitting end of the measuring light and the incident end of the reflected light of the light receiving optical fiber 17 are fixed so as to penetrate substantially the central portion of the arch contact plate 57 and face the arch 16 of the foot portion 15.

A moving plate 58 is attached to the rear end of the optical fiber holding pipe 53. The moving plate 58 has a cylindrical guide member 61 which is fitted onto a guide post 59 fixed to the reference table 23 so as to vertically project downward and is guided vertically. A motor support plate 62 is fixed to the tip of the guide post 59, and a z-axis position sensor 63 for detecting the position of the arch contact plate 57 in the z-axis direction and the arch contact plate are fixed on the motor support plate 62. The moving motor Mz of the contact plate 57 is fixed. A moving plate bracket 65 is arranged between the moving motor Mz and the moving plate 58, and a screw shaft 66 attached to the output shaft 64 of the moving motor Mz is screwed to the moving plate bracket 65. ing. Between the moving plate bracket 65 and the moving plate 58, the arch contact plate 57 is provided on the arch 1 of the foot 15.
A contact pressure sensor 67 for detecting the contact pressure to 6 is provided.

When the moving motor Mz rotates, the arch contact plate 57 moves in accordance with the amount of rotation of the output shaft 64.
Move in the axial direction. The amount of movement of the contact plate 57 in the z-axis direction is detected by the z-axis position sensor 63. When the arch contact plate 57 moves in the z-axis direction and contacts the arch 16 of the foot portion 15, the contact pressure is output from the contact pressure sensor 67. The emission position of the measurement light emitted from the arch contact plate 57 and the incident position of the reflected light are loosely fitted in the holes 2a and 2b formed in the object table 2 of FIG. The object table 2 is set as an intersection P in the direction indicated by the illustrated indexes 68 and 69.
It can be confirmed by the operator from above.

The light receiving sensor 13, the reference light sensor 12, the load cell 19, the x-axis position sensor 34, and the y-axis position sensor 3 provided in the spectroscopic analyzer 3 having the above-described structure.
The signal output from the 8 or the like is the arithmetic and control unit 4 described below.
Supplied to The arithmetic and control unit 4 is composed of a personal computer, and as shown in FIG. 2, a central processing unit (hereinafter referred to as CPU) 71, a read-only memory (hereinafter referred to as ROM) 72, a read / write memory. (Hereinafter referred to as RAM) 73 and interface circuits 74 to 79 and interface circuits 81 to 85. The CPU 71 uses the bus 86 to
It is connected to the ROM 72, the RAM 73, the interface circuits 74 to 79 and the interface circuits 81 to 85.

In the interface circuit 74, the x-axis direction position signal from the x-axis position sensor 34 and the x-axis direction movement table 24 is sent from the y-axis position sensor 38 to the y-axis direction movement table 25.
And the z-axis position signal of the arch contact plate 57 are input from the z-axis position sensor 63 and the contact pressure sensor 67 from the contact pressure sensor 67, respectively.
The contact pressure signal of the foot 15 to the arch 16 is input, and the heel contact signal is input from the heel contact sensor 51. Further, the spectrum intensity signal of the reflected light of the measuring light reflected from the foot 15 of the person to be measured is input to the interface circuit 75 from the light receiving sensor 13, and the interface circuit 12 monitors the fluctuation of the light source 11 of the measuring light. A monitor signal is input from the reference light sensor 12 to
The weight signal of the person to be measured is input from the load cell 19 to 7. Furthermore, a necessary operation command signal is input from the keyboard 87 to the interface circuit 78 in accordance with the operation content of the operator's keyboard 87. The interface circuit 79 is connected to a communication port 88 used when communicating with a host computer connected to the arithmetic processing unit 4.

On the other hand, a motor drive circuit 91 is connected to the interface circuit 81. The motor drive circuit 91 is composed of a power device such as a power transistor,
As shown in FIG. 1, it is attached to the side surface of the lower housing 8 of the spectroscopic analysis device 3. The motor drive circuit 91 has a structure shown in FIG.
The x-axis movement motor Mx, the y-axis movement motor My, the z-axis movement motor Mz, and the position adjustment motor 42 described in FIG. 4 are connected. Further, the interface circuit 8
A storage device 5 such as a hard desk is connected to 2.
Furthermore, the CRT display 6 is connected to the interface circuit 83, and the printer 7 is connected to the interface circuit 84. A light source control circuit 92 for controlling the light source 11 of the measurement light is connected to the interface circuit 85.

Next, referring to the flow charts shown in FIGS. 6 and 7, the operation of the body fluid component concentration measuring apparatus 1 equipped with the position reproducing apparatus having the above-described structure will be described in advance. The method of reproducing the measurement position to the selected position will be described.

Measurement Position Registration Mode In the measurement position registration mode shown in FIG. 6, the body fluid component concentration measuring apparatus 1 is turned on and the operator operates the keyboard 8
When the measurement position registration mode is selected from 7, and the start of the measurement position registration mode is instructed, the measurement position registration routine starts, the CPU 71 of the arithmetic and control unit 4 is initialized (step S1), and the RAM 73 is cleared. (Step S2). After that, the CPU 71 of the arithmetic and control unit 4
The initial data stored in the storage device 5 is loaded into the RAM 73 (step S3), and the x-axis direction movement table 2 is loaded.
4, the y-axis direction moving table 25, the arch contact plate 57, and the foot positioning member 41 are moved to their initial positions (step S4).

A number for specifying the person to be measured from the keyboard 87, for example, No. 3 is input (step S5). After that, the entered number No. The person to be measured 3 rides on the object table 2 (step S6). At this time, the arch contact plate 57 is located below the arch 16 of the right foot 15, and the inside ankle 15b of the right foot 15 contacts the ankle contact plate 45 of the foot positioning member 41. As described above, the measurement subject moves the position of the right foot 15 on the object table 2. In this state, the operator operates the keyboard 87 so that the intersection point P between the direction of the index 68 and the direction of the index 69 is approximately in the center of the arch 16 of the foot 15, as shown in FIG. The moving table 24 and the y-axis direction moving table 25 are moved to select a measurement point (step S7).

Next, the foot positioning member 41 is moved (step S8), the heel contact plate 44 contacts the heel 15a of the foot 15, and when the heel contact sensor 51 outputs a contact signal, the foot contact sensor 51 outputs the contact signal. The part positioning member 41 is stopped (steps S8 and S9). Further, the contact plate 57 is raised by the output of the contact signal (step S1).
0). The arch contact plate 57 contacts the arch 16 of the foot 15 of the subject, and when the contact pressure reaches a preset value, the arch contact plate 57 stops (steps S10 and S11). .

In this state, the weight of the person to be measured is measured from the output of the load cell 19 (step S12). After that, the blood glucose level measurement routine of FIG.
The glucose concentration detection routine from step (step S13-1) to step (step S13-7) in 3) is executed to measure the blood glucose level of the subject. Further, the weight obtained by the measurement, the contact pressure of the arch contact plate 57, the position of the foot positioning member 41, the x-axis direction moving table 24.
, The position of the y-axis direction movement table 25, and the number No. for specifying the person to be measured, which is input in the step (step S5) of already inputting the number to specify the person to be measured from the keyboard 87 and stored in the RAM 73. Each data item 3 is registered in the storage device 5 (step S14).

After the above steps (steps S1 to S14) are completed, the person to be measured descends from the object table 2 of the spectroscopic analyzer 3 (step S15), and it is determined that there is the next measurement (step S16). Then, returning to the execution of step S3, if it is determined that there is no next measurement (step S16),
The measurement position registration routine ends.

Blood glucose level measurement mode When the blood glucose level measurement mode shown in FIG. 7 starts, the CPU 71 of the arithmetic and control unit 4 is initialized (step S2).
1), the RAM 73 is cleared (step S22).
After that, the CPU 71 of the arithmetic and control unit 4 loads the initial data stored in the storage unit 5 into the RAM 73 (step S23), and the x-axis direction moving table 24, the y-axis direction moving table 25, the arch contact plate 57 and The foot positioning members 41 are moved to their initial positions (step S24).

The registration number of the person who measures the glucose concentration registered in the registration mode shown in FIG. 3 is input from the keyboard 87 (step S25), the CPU 71 of the arithmetic and control unit 4 has the No. 3 which is already registered in the storage unit 5 in the registration mode. 3
The weight of the person having the registration number of, the contact pressure of the arch contact plate 57, the position of the foot positioning member 41, the position of the x-axis direction moving table 24, the y-axis direction moving table 25.
Each data at the position of is loaded into the RAM 73.
Then, the CPU 71 of the arithmetic and control unit 4 determines the position of the foot part positioning member 41 based on each data of the position of the foot part positioning member 41, the position of the x-axis direction moving table 24, and the position of the y-axis direction moving table 25. , The position of the x-axis direction moving table 24 and the position of the y-axis direction moving table 25 are reproduced (step S26).

In the above state, the registration number No. 3 said person to be measured rides on the object table 2 of the spectroscopic analyzer 3 (step S27), and the heel 15b and heel 15a inside the foot 15 on the right side thereof are respectively applied to the heel of the foot positioning member 41. The contact plate 45 and the heel contact plate 44 are brought into contact with each other. After that, the arch contact plate 57 rises (step S28) to contact the arch 16 of the foot portion 15, and when the contact pressure signal output from the contact pressure sensor 67 reaches a predetermined value set in advance,
The arch contact plate 57 stops (step S2).
9). Thereby, the registration number No. The position of the foot part 15 on the right side of the person to be measured in No. 3 is reproduced to the position at the time of registration, and the contact pressure of the arch contact plate 57 is also reproduced to the value at the time of registration. Then, after the weight measurement is executed by the output of the load cell 19 (step S30), the next glucose concentration detection routine (step S13) is executed.

In the glucose concentration detection routine (step S13), the CPU 71 of the arithmetic and control unit 4 operates as shown in FIG.
Also, the absorbance is calculated based on the spectral intensity of the reflected light from the foot 15 input from the light receiving sensor 13 described in FIG. 3 (step S13-1), and the glucose concentration calculation is executed (step S13-2). The CPU 71 of the arithmetic and control unit 4 then receives the arch contact plate 57.
It is determined whether or not the contact pressure correction command signal for correcting the detected glucose concentration is present in the RAM 73 based on the contact pressure of (step S13-3). CPU 7 above
1 is the glucose concentration calculation step (step S when the contact pressure correction command signal exists in the RAM 73).
The glucose concentration calculated in 13-2) is corrected by the contact pressure (step S13-4), and when the contact pressure correction command signal does not exist in the RAM 73, the correction by the contact pressure is not performed. . The CPU 71 of the arithmetic and control unit 4 then transmits the registration number No. 1 measured in the weight measuring step (step S30). It is determined whether or not the weight correction command signal for correcting the detected glucose concentration exists in the RAM 73 according to the body weight of the person to be measured 3 (step S13-5). When the weight correction command signal is present in the RAM 73, the CPU 71 corrects the glucose concentration with the weight (step S13-6), and when the weight correction command signal is not present in the RAM 73, the weight correction is not performed. Not performed. The CPU 71 of the arithmetic and control unit 4
The glucose concentration data and body weight data detected in steps S13-1 to S13-6 are output to the CRT display 6. Also, CRT
The data displayed on the display 6 can be printed out by the printer 7 according to a command from the keyboard 87 (step S13-7).

After the above steps are completed, the person to be measured descends from the object table 2 of the spectroscopic analyzer 3 and it is judged that there is the next measurement (step S31), and the process returns to the execution of step S24 to perform the next measurement. If it is determined that there is not, the blood glucose level measurement mode ends.

As described above, the person to be measured gets on the object table 2 of the spectroscopic analyzer 3 and the first selected measurement position is registered in the arch 16 of the foot 15 of the person to be measured. When measuring the blood glucose level thereafter, the blood glucose level can always be measured at the same measurement position. As a result, when the glucose concentration is measured by detecting the reflected light of the measurement light projected on the arch 16 of the foot 15 of the measurement subject, the reproducibility of the measurement position is significantly improved, and the measurement value due to the change in the measurement position. Can be suppressed. Further, the contact pressure of the arch contact plate 57 on the arch 16 is always the same value, the optical path length of the incident measurement light and the optical path length of the reflected light are constant, and the glucose concentration calculated by the absorbance calculation is brought into contact with the arch. By correcting the contact pressure of the plate 57, it is also possible to correct the variation in the measurement of the glucose concentration due to the contact pressure of the arch contact plate 57. Further, by correcting the glucose concentration detected by the absorbance calculation based on the body weight of the person to be measured, it is possible to correct the change in glucose concentration due to the body weight. Furthermore, the measurement light is projected onto the measurement position of the arch 16 of the foot portion 15 of the person to be measured using the measurement light optical fiber 14, and the reflected light is guided to the light receiving sensor 13 by the light receiving optical fiber 17. Therefore, the degree of freedom in arranging the light source 11 and the light receiving sensor 13 for the measurement light is increased, and the body fluid component concentration measuring device 1 can be designed easily and compactly.

(Second Embodiment) A spectroscopic analyzer 3 of a body fluid component concentration measuring apparatus according to another embodiment of the present invention.
a is shown in FIG. The spectroscopic analyzer 3a is the same as that of the first embodiment.
In the spectroscopic analysis device 3 of the body fluid component concentration measuring device 1 described in 1., the measuring light optical fiber 14 that guides the measuring light to the measuring position of the arch 16 of the foot 15 of the subject and the measuring light projected at the measuring position. Receiving light from sensor 13
In place of the optical fiber 17 for receiving light which is guided to, the integrating sphere 101 is arranged below the arch contact plate 57 and the measuring light is generated between the integrating sphere 101 and the moving plate 58, as shown in FIG. The measuring light source 11 is arranged, and the measuring light is projected from the measuring light source 11 to the measuring position through the measuring light projection holes 102, 103 and 104 provided in the integrating sphere 101 and the arch contact plate 57, and the foot 15 The reflected light from the light may be detected by the light receiving sensor 13 arranged on the integrating sphere 101. In this way, the integrating sphere 101
More reflected light can be collected by the light receiving sensor 1
Since the output level of 3 increases, an amplifier with a small gain can be used as an amplifier for amplifying the output of the light receiving sensor 13, and the cost of the signal processing circuit can be reduced. In addition, in FIG. 8, the portions corresponding to those in FIG. 3 are denoted by the corresponding reference numerals, and the duplicate description will be omitted. In addition, in the second embodiment, the system configuration other than the spectroscopic analysis device 3a is exactly the same as that described in FIGS. 1 and 2, and therefore the description thereof is omitted.

(Embodiment 3) A spectroscopic analyzer 3 of a body fluid component concentration measuring apparatus according to another embodiment of the present invention.
b is shown in FIG. This spectroscopic spectroscopic device 3b is the spectroscopic analysis device 3 of the first embodiment described with reference to FIGS.
In the above, in the arch 16 of the foot 15 of the person to be measured, the transmitted light of the measuring light projected from the optical fiber 14 for measuring light is received by the optical fiber 17 for light receiving arranged on the instep of the foot 15. The light is received by the portion 111. In the light receiving portion 111, the tip of the optical fiber 17 for receiving the transmitted light opposes the tip of the optical fiber 14 for measuring light on the side of the arch contact plate 57, and moves vertically to a post 112 fixed to the reference table 23. It is fixed to the tip of an arm 114 that is movably attached, and the foot 15 of the person to be measured is arranged between the optical fiber 14 for measurement light and the optical fiber 17 on the side receiving the transmitted light. The configuration of the portion of the spectroscopic analysis device 3b of FIG. 9 other than the light receiving portion 111 of the above-described light receiving optical fiber 17 is exactly the same as the configuration of the corresponding portion of the spectroscopic analysis device 3 described in FIG. Therefore, in FIG. 9, the portions corresponding to those in FIG. 3 are denoted by the corresponding reference numerals, and the duplicate description will be omitted. Further, in Embodiment 3, the system configuration other than the spectroscopic analysis device 3b is exactly the same as that described in FIG. 1 and FIG.

With such a configuration, it is possible to detect the transmitted light transmitted through the foot portion 15 and detect the glucose concentration based on the detected light.

(Embodiment 4) The body fluid component concentration measuring apparatus shown in FIG. 10 is an arithmetic and control unit 4, a storage device 5, a CRT of the body fluid component concentration measuring apparatus 1 of the embodiment 1 described in FIGS. The display 6 and the printer 7 are housed in one case 113, and the lower housing 8 of the spectroscopic analysis device 1 is housed.
The case is fixed to the tip of a column 115 fixed to the front part of the. By providing the body fluid component concentration measuring device 1b having such a configuration, the person to be measured can easily measure his or her blood glucose level, other body fluid component concentrations, and body weight in a manner that measures the weight with a so-called weight scale. It can be used for daily health management.

[0068]

As described above in detail, according to the invention of claim 1 of the present invention, the position of the specific part of the foot of the subject is registered and the measured position is reproduced. Since the foot of the person to be measured is positioned at the registered position, the measurement position can be reproduced with high accuracy.

According to the invention of claim 2, in addition to the effect of the invention of claim 1, by registering the positions of the heel and ankle of the foot of the person to be measured, high reproducibility is achieved. The measurement position can be reproduced.

Further, according to the invention of claim 3,
In addition to the effect of the invention according to claim 1 or 2, since the information for specifying the person to be measured is registered together with the position of the specific part of the foot of the person to be measured, the information for specifying the person to be measured is registered. The measured position of the foot can be easily reproduced.

Further, according to the invention of claim 4, in addition to the effect of the invention of any one of claims 1 to 3, the arch of the foot is curved upward, and the curved portion Since the measurement position is set at, the reproducibility of the measurement conditions is improved.

Furthermore, according to the invention of claim 5, in addition to the effect of the invention of any one of claims 1 to 4, the glucose concentration can be measured by the foot of the subject. .

According to the invention of claim 6, the position of the foot positioning means is reproduced based on the position information of the foot positioning means of the subject registered in the position registration means.
By positioning the foot of the person to be measured by the foot positioning means whose position has been reproduced, the measurement position can be reproduced with high reproduction accuracy.

According to the invention of claim 7, in addition to the effect of the invention of claim 6, the object table supporting mechanism is used to two-dimensionally move the object table to the projection optical system. Since it can be moved in the x-axis direction and the y-axis direction, the object table is moved according to the size of the subject's foot, and the measurement position is selected regardless of the size of the subject's foot. be able to.

Further, according to the invention of claim 8,
In addition to the effect of the invention as set forth in claim 6 or 7, in addition to the heel contact plate and the heel contact plate of the foot position locating means, the heel part and the heel part of the measurement subject's foot part are brought into contact, respectively The position of can be reproduced.

Further, according to the invention of claim 9, in addition to the effects of the inventions of claims 6 to 8, the registration means provides information for specifying the person to be measured to specify the foot of the person to be measured. Since the position is registered together with the position of the part, the registered measurement position of the foot can be easily reproduced from the information specifying the person to be measured.

Further, according to the invention of claim 10, in addition to the effect of the invention of any one of claims 6 to 9, the arch of the foot portion is curved upward, and the curved portion Since the measurement position is set at, the reproducibility of the measurement conditions is improved.

Furthermore, according to the invention of claim 11, in addition to the effect of the invention of any one of claims 6 to 10, the measurement position of the foot is reproduced at a preselected position. The glucose concentration can always be measured under constant measurement conditions.

Furthermore, according to the invention of claim 12, in addition to the effect of the invention of any one of claims 6 to 11, since the arithmetic control means is constituted by a personal computer, the position reproduction The device can be realized at low cost.

According to the thirteenth aspect of the present invention, there is provided a registration means for registering the position information of the foot positioning means adjusted by the position adjusting means, and the foot whose position is reproduced based on the registered position information. The positioning means reproduces the position of the subject's foot on the object table means, projects the measurement light from the projection optical system to the measurement position of the foot, and receives the light transmitted or reflected from the measurement position. Then, the light transmitted or reflected from the measurement position is detected, and the concentration of a specific component of the body fluid of the measurement subject is detected based on the obtained detection light. Can be higher.

According to the invention of claim 14,
In addition to the effect of the invention as set forth in claim 13, the object table support mechanism is used to two-dimensionally x the object table with respect to the projection optical system.
Since it can be moved in the axial direction and the y-axis direction,
Move the object table according to the size of the foot of the person to be measured,
It is possible to measure the concentration of a specific component of the body fluid of the subject regardless of the size of the foot of the subject.

Further, according to the invention of claim 15, in addition to the effect of the invention of claim 13 or 14, the heel contact plate and the heel contact plate of the foot positioning means reproduced at the registered position The measurement position is reproduced by bringing the ankle and heel of the person's foot into contact with each other, and the body fluid component concentration can always be detected under constant conditions.

Furthermore, according to the invention of claim 16, in addition to the effect of the invention of any one of claims 13 to 15, the object table is supported on the weight sensor. In addition to the specific body fluid component concentration of the subject on the subject table, the weight can also be measured.

Furthermore, according to the invention of claim 17, in addition to the effect of the invention of claim 16, a specific body fluid component concentration to be measured based on the weight of the subject output from the weight sensor is measured. Can be corrected. In addition, the body weight change of the person to be measured is measured in advance, and the standard value of the body weight for measuring the body fluid component concentration is set and stored at a value higher than the maximum value of the body weight change, and the body weight sensor measures the body fluid component concentration during measurement. By correcting the deficient amount of the measured body weight with respect to the standard value of the stored body weight, it becomes unnecessary to correct the specific body fluid component concentration measured by the arithmetic and control unit, and at the same time, the foot of the measured person is measured. The contact condition of the arch contact member can be stabilized.

Furthermore, the invention according to claim 18 is
In the invention according to any one of claims 13 to 17, since the arch contact member moves up and down in a direction perpendicular to the object table by the elevating mechanism, the degree of curvature of the arch of the foot of the subject is measured. Regardless of the above, the arch contact mechanism can be brought into contact with the arch of the foot of the subject.

Furthermore, the invention according to claim 19 is
In the invention according to any one of claims 13 to 15, since the contact pressure of the arch contact member to the arch of the foot of the person to be measured can be known by the contact pressure detection sensor, the contact pressure is detected. The contact pressure of the arch contact member to the arch of the foot of the person to be measured can be controlled to be constant by the output of the sensor.

Further, the invention according to claim 20 is
In addition to the effect of the invention described in claim 19, it is possible to correct the specific body fluid component concentration measured based on the weight of the measurement subject output from the weight sensor.

Furthermore, the invention according to claim 21 is as follows.
In addition to the effect of the invention described in any one of claims 13 to 20, since the projection optical system means and the light receiving optical system means are made of flexible optical fibers, the degree of freedom of arrangement of the light source and the light receiving sensor is increased. As a result, the degree of freedom in designing the body fluid component concentration measuring device is increased, and the shape can be made compact.

Furthermore, the invention according to claim 22 is
In addition to the effect of the invention described in any one of claims 13 to 20, since the light receiving optical system means is composed of an integrating sphere, a large amount of light reflected or transmitted from the foot of the subject can be collected. Since the output level of the light receiving sensor is large and the signal processing is easy, an inexpensive amplifier for amplifying the output of the light receiving sensor can be used.

Furthermore, the invention according to claim 23 is
In addition to the effect of the invention according to any one of claims 13 to 22, in addition to the information on the measurement position of the foot of the subject whose registration means measures the body fluid component concentration, information for identifying the subject is provided. Since it is stored, the measurement position of the foot of the person to be measured can be easily reproduced by the information specifying the person to be measured.

Furthermore, the invention according to claim 24 is
In addition to the effect of the invention described in any one of claims 13 to 23, the glucose concentration can be constantly measured at a fixed position of the foot of the subject.

Furthermore, the invention according to claim 25 is
In addition to the effect of the invention described in any one of claims 13 to 24, since the arithmetic and control unit is composed of a personal computer, the cost of the body fluid component concentration measuring device can be reduced.

[Brief description of the drawings]

FIG. 1 is a system configuration diagram of a first embodiment of a body fluid component concentration measuring apparatus according to the present invention.

FIG. 2 is a block diagram showing a system configuration of the body fluid component concentration measuring apparatus of FIG.

FIG. 3 is a vertical cross-sectional view showing a configuration of a spectroscopic analyzer of the body fluid component concentration measuring apparatus of FIG.

FIG. 4 is an explanatory diagram showing a configuration of an object table support mechanism of the spectroscopic analyzer of FIG.

FIG. 5 is an explanatory view showing a state in which the heel and the heel of the foot are in contact with the heel contact plate and the heel contact plate of the foot positioning member, respectively.

FIG. 6 is a flow of a registration mode.

FIG. 7 is a flow of measurement mode.

FIG. 8 is a vertical cross-sectional view of a spectroscopic analysis device in a body fluid component concentration measurement device according to a second embodiment.

FIG. 9 is a longitudinal sectional view of a spectroscopic analysis device in a body fluid component concentration measurement device according to a third embodiment.

FIG. 10 is a perspective view showing an overall configuration of a body fluid component concentration measuring device according to a fourth embodiment.

FIG. 11 is measurement data showing a change in the measured value of the blood glucose level due to a change in the incident position of the incident light incident on the measurement object.

FIG. 12 is measurement data showing changes in the measurement pressure of the blood glucose level due to changes in the contact pressure between the measurement target and its mounting table.

[Explanation of symbols]

1 Body fluid component concentration measuring device 1b Body fluid component concentration measuring device 2 Specimen table 2a hole 2b hole 3 spectroscopic analysis device 3a spectroscopic analysis device 3b spectroscopic analysis device 4 arithmetic control device 5 storage device 6 CRT display 7 printer 8 lower housing 9 bellows Reference Signs List 11 light source 12 reference light sensor 13 light receiving sensor 14 optical fiber for measurement light 15 foot 15a heel 15b heel 16 arch of foot 17 light receiving optical fiber 18 base plate 19 load cell 19a protrusion 21 coil spring 22 specimen base support mechanism 23 reference table 23a Protrusion 24 x-axis direction moving table 25 y-axis direction moving table 26 x-axis direction guide groove 27 roller bearing unit 28 y-axis direction guide groove 29 roller bearing unit 31 output shaft 32 screw shaft 33 bracket 34 x-axis position sensor 35 output Axis 36 Skrillyu shuff 37 bracket 38 y-axis position sensor 41 foot positioning member 42 position adjustment motor 43 position detection sensor 44 heel contact plate 45 heel contact plate 46 coupling member 47 guide member 48 output shaft 49 screw shaft 50 screw member 51 heel contact Sensor 52 Fitting hole 53 Optical fiber holding pipe 54 Hole 55 Hole 56 Hole 57 Arch contact plate 58 Moving plate 59 Guide post 61 Guide member 62 Motor support plate 63 z axis position sensor 64 Output shaft 65 Moving plate bracket 66 Skrill shaft 67 Contact pressure sensor 68 Index 69 Index 71 Central processing unit (CPU) 72 Read only memory (ROM) 73 Read / write memory (RAM) 74 to 79 Interface circuit 81 to 85 Interface circuit 86 Bus 87 Keyboard 88 Communication port 91 Mo Drive circuit 92 light source control circuit 101 integrating sphere 102 measurement light projection hole 103 measurement light projection hole 104 measurement light projection hole 111 light receiving portion 112 post 113 case 114 arm 115 pillar Mx x axis drive motor My y axis drive motor Mz z axis drive Motor A ₁ Direction of flow of measurement light A ₂ Direction of light transmitted and reflected from the subject P Intersection point

Claims (25)

[Claims] 1. The measurement light is projected onto the sole of the foot of the person to be measured,
When the light transmitted or reflected from the foot of the person to be measured is detected and the concentration of the specific component of the body fluid of the person to be measured is measured based on the obtained detection light, the measurement light is preselected and registered. A method for reproducing a measurement position in which the light is incident on a predetermined measurement position, the position of a specific part of the foot of the person being measured is registered when the measurement position is registered, and the foot of the person being measured is reproduced when the measurement position is reproduced. A method for reproducing a measured position, characterized in that the above-mentioned specific part of the part is positioned at the position at the time of registration. 2. The method for reproducing a measurement position according to claim 1, wherein the specific parts of the foot of the person to be measured are the heel and the ankle. 3. The method for reproducing a measurement position according to claim 1, wherein the measurement position is registered with information for specifying a person to be measured who measures the concentration of the specific component of the body fluid. 4. The measurement position reproducing method according to claim 1, wherein the measurement position is set on the arch of the foot of the subject. 5. The measurement position reproducing method according to claim 1, wherein the specific component concentration is a glucose concentration. 6. The projection optical system projects measurement light on the back of the foot of the person to be measured, detects the light transmitted or reflected from the foot of the person to be measured, and detects the light based on the detected light obtained. A measurement position reproducing device for making the measurement light incident on a predetermined measurement position selected in advance when measuring the concentration of a specific component of the body fluid of the measurement subject, the test subject placing the foot portion of the measurement subject. An object stand means, a foot part positioning means for positioning the foot of the person to be measured on the object table means by a specific portion thereof, and a position of the foot part positioning means on the object table means. Position adjusting means for adjusting, position registering means for registering the position information of the foot positioning means adjusted by the position adjusting means, and the position adjusting means based on the position information stored in the position registering means. Controlling the above-mentioned foot positioning means Position measuring position repeatability apparatus being characterized in that and a calculation control means for adjusting the. 7. The object table support mechanism is supported on an object table support mechanism that two-dimensionally relatively movably supports the projection optical system. Measuring position reproduction device. 8. The measurement position according to claim 6 or 7, wherein the foot positioning means includes a heel contact plate and a heel contact plate that respectively contact the heel and heel of the foot of the subject. Reproduction device. 9. The measurement according to claim 6, wherein the position registration means stores, together with the measurement position, information for specifying a person to be measured who measures the concentration of the specific component of the body fluid. Position reproduction device. 10. The measurement position is set on the arch of the foot of the person to be measured.
The measurement position reproducing device according to any one of 1. 11. The measurement position reproducing device according to claim 6, wherein the specific component concentration is a glucose concentration. 12. The measurement position reproducing device according to claim 6, wherein the arithmetic and control unit is a personal computer. 13. The detection obtained by projecting the measurement light on a predetermined measurement position on the back of the foot of the person to be measured and detecting the light transmitted or reflected from the foot of the person to be measured. A body fluid component concentration measuring device for measuring the concentration of a specific component of a body fluid of a subject based on light, comprising: a subject table means on which a foot of the subject person is placed; and the subject table means. Foot part positioning means for positioning the foot part of the person to be measured by the specific part, position adjusting means for adjusting the position of the foot part positioning means on the object table means, and position adjusting means for adjusting the position. The position registration means for registering the position information of the foot part positioning means, the projection optical system means for projecting the measurement light to the measurement position, and the projected measurement light transmitted or reflected through the foot part of the measurement subject. A light receiving optical system unit for receiving light, and the light receiving unit Detecting light intensity detecting means for detecting the intensity of the detecting light transmitted or reflected from the foot of the person to be measured received by the academic system means, and the position based on the position information stored in the position registering means. Calculation control means for controlling the adjusting means to adjust the position of the foot positioning means and calculating the concentration of a specific component in the body fluid of the measurement subject based on the intensity of the detected light; A body fluid component concentration measuring device comprising: an output unit that outputs a component concentration. 14. The object stage support means is supported on an object table support mechanism that two-dimensionally relatively movably supports the projection optical system. Body fluid concentration measuring device. 15. The body fluid component according to claim 13, wherein the foot positioning means comprises a heel contact plate and a heel contact plate that respectively contact the heel and ankle of the foot of the subject. Concentration measuring device. 16. The body fluid component concentration measuring apparatus according to claim 13, further comprising a weight sensor, wherein the object table is supported on the weight sensor. 17. The method according to claim 1, wherein the concentration of the specific component in the body fluid of the measurement subject calculated by the calculation control means is corrected based on the weight output from the weight sensor.
6. The body fluid component concentration measuring device according to 6. 18. An arch contact member for abutting the arch of the foot of the subject and projecting the measurement light emitted from the projection optical system means onto the arch, and the arch contact member for the arch contact member. The body fluid component concentration measuring device according to any one of claims 13 to 17, further comprising an elevating mechanism that elevates and lowers in a direction perpendicular to the table. 19. The elevating mechanism includes a contact pressure detection sensor for detecting a contact pressure of the arch contact member on the arch of the foot of the person to be measured.
16. The body fluid component concentration measuring device according to any one of 1 to 15. 20. The concentration of the specific component in the body fluid of the measurement subject calculated by the calculation control means is corrected based on the contact pressure of the contact member output from the contact pressure detection sensor. The body fluid component concentration measuring device according to claim 19. 21. The body fluid component concentration measuring device according to claim 13, wherein the projection optical system means and the light receiving optical system means are constituted by optical fibers. 22. The body fluid component concentration measuring apparatus according to claim 13, wherein the projection optical system means and the light receiving optical system means are formed by integrating spheres. 23. The position registration means stores, together with the measurement position, information for specifying a person to be measured who measures a concentration of a specific component of the body fluid.
2. The body fluid component concentration measuring device according to any one of 2. 24. The body fluid component concentration measuring device according to claim 13, wherein the specific component concentration is a glucose concentration. 25. The body fluid component concentration measuring device according to claim 13, wherein the arithmetic and control unit is a personal computer.