JPH088929B2 - Medical syringe - Google Patents

Description

Description: TECHNICAL FIELD The present invention relates to a medical injector, and a syringe cylinder and at least one movable in the cylinder by using a piston rod.
One syringe piston, as well as one with a cannula-side closure for the syringe cylinder and a finger support at the end of the syringe cylinder opposite the closure.

[Prior Art and Problems to be Solved by the Invention] The syringe as described above is known and is on the market in many embodiments. However, these syringes are assembled from many single components, which are often made in a wasteful manufacturing process, which makes the cost for single-use syringes extremely high. It has some drawbacks.

A syringe as mentioned at the beginning can be assembled with fewer and easier components than are easily made,
Furthermore, the subject of the present invention is to configure the individual components of the respective required applications and the correspondingly modified shape of the embodiments in such a way that they can be used in the same way. ing.

[Means and Action for Solving the Problems] According to the present invention, the syringe cylinder is configured as a cylindrical tube, and the cylindrical tube has a relatively soft rubber elastic material at the axial end. In a syringe for abutting a flat cylindrical sealing disc of material, which disc is fitted in a receiving flange of the closure and seals the syringe cylinder against the closure, said syringe cylinder being at least its At the cannula end there is a ring flange which is a radially outwardly projecting locking projection for the closure, the closure being closed with a releasably mounted tip cap. And the cap has an axially oriented jar that projects into a passage hole in the closure that is provided for receiving a cannula. Has a le, sealing disc is provided with a central opening, the free end of the journal is the problems are solved by that closely contact with the inner edge of the opening.

The essence of the advantages achieved by the invention lies in the possibility, in large part, of the possibility of using a simple cylindrical tube, mainly of glass, as a base body for a syringe which can be easily cut to the desired extent from a longer tube. . By melting the glass tube on the front side for the treatment of sharply angled cut surfaces, a ring-shaped flange provided on the front side can be constructed at the same time. Following this, a closure adapted for the respective application can be mounted and locked without any special adaptation.

In a first embodiment of the invention the closure may comprise a rigidly attached cannula carrying a radially outwardly directed ring-shaped flange,
Mounted on the flange is a cannula protective cap that surrounds the cannula, the end of the cannula facing the syringe cylinder protruding into the receiving flange and of the central opening in the sealing disc. It abuts the edge. In said embodiment, the syringe is already completed for use, so that for use only the cannula protective cap has to be removed and an already pre-filled finished syringe poses a problem. As far as is possible, subsequently only the substance to be administered has to be sucked up into the syringe. In this case, in a purposeful refinement, the cannula protective cap is made of a hard-flexible technical material and has a hollow interior, the hollow space surrounding the cannula being at least in the region of the cannula tip. It may be intended to be filled with a soft-flexible, hermetically-sealed industrial material. In this way a suitable protection of the cannula is obtained, while at the same time
It is guaranteed that the cannula is sealed without the risk of damage to its tip.

However, likewise, the closure is closed with a releasably fastened tip cap, which cap comprises an axially oriented journal, the journal for receiving a cannula of the closure. It is also possible to plan to project into the provided passage hole. The free end of the journal may then project at most to the sealing disc, or the sealing disc may have a central opening and the free end of the journal abuts the inner edge of the opening.

Furthermore, within the framework of the invention, the closure may also comprise a connecting neck for the attachment of a cannula with a needle sleeve. There, the needle is placed on the connecting neck after removal of the tip cap.

The syringe is configured as a pre-filled finished syringe, the finished syringe being provided with a central stopper, the chamber for receiving solvent being between the syringe piston and the central stopper, And the chamber on the cannula side contains the active substance in unmelted, freeze-dried form, and the syringe cylinder has a bypass for the passage of the solvent into the chamber on the cannula side. If, in addition, within the framework of the invention, the closure has at least two locking positions on the syringe cylinder, and the closure is connected to the receiving flange and runs radially. A boring is provided, the passing boring being connected to the chamber on the cannula side in the first locking position in the direction of attachment of the closure on the syringe cylinder, the front side of the syringe cylinder being In contact with the second locking position in the closed disk, to be covered by the overmold surface of the syringe cylinder it has been scheduled. In this case, as long as the closure is in its first locking position, there is an external connection of the chamber on the cannula side to the outside through the passage hole, so that in the melted form The active substance introduced into the chamber can be freeze-vacuum dried through a through hole. Subsequently, the chamber is aseptically closed by simply further pressing the closure into the second locking position.

In a syringe as described above, the piston rod may have a male thread on the side facing the syringe piston and a corresponding female thread on the finger support, while the side of the piston rod opposite the syringe piston is the rod. It has a relatively small diameter which allows for free movement of the. Therefore, the syringe piston can only be moved from its starting position to the cannula end by the rotational movement of the syringe piston, which automatically limits the speed of movement of the piston. This causes the solvent to
It is guaranteed to be guided slowly into the anterior chamber containing the active substance. Only after the screw of the piston rod has been released from the finger support, the syringe piston can then be displaced only by pressing on the piston rod for the administration of the dissolved active substance.

Finally, within the framework of the invention, a protective cap is placed on the closure, which cap surrounds the closure in form connection, the protective cap being directed towards its own finger support. The side carries a clamping ring which is connected via a thin separating web to a protective cap, which is permanently attached in a non-releasable manner to the closure, and A protective cap carries an inwardly axially arranged journal, which may be intended to close the cannula opening of the closure. The integrity of the protective cap then ensures that the contents of the syringe are still in their original, sterile condition.

[Examples] In the following, the present invention will be described in detail using the examples depicted in the drawings.

The illustrated medical syringe comprises a syringe cylinder 1 and at least one syringe piston 3 movable with a piston rod 2 in the cylinder. The syringe cylinder 1 is provided at one end with a closure 4, which at the same time serves for the reception of the cannula 5.
On the other hand, a conventional finger support 6 is arranged at the other end.

In detail, the syringe cylinder 1 is constructed as a cylindrical tube, which has a ring flange 1.1 at the end on the cannula side. The ring flange 1.1 forms a locking projection for the closing part 4 which projects radially outward, the front side in the axial direction consisting of a relatively softly adjusted rubber elastic industrial material flat cylinder. It is in contact with the closed disk 7 in the shape of a circle. The sealing disk 7 is a closing part 4
It is fitted in the receiving flange 4.1 of 1. and seals the syringe cylinder 1 against the closure 4.

In the embodiment depicted in FIGS. 1 and 2, the closure 4 comprises a rigidly attached cannula 5, which closure 4 further extends radially outwards. It carries an oriented ring flange 8. The ring flange 8 acts as a stop fit for a cannula protective cap 9 surrounding the cannula 5.
The end of the cannula 5 towards the syringe cylinder 1 then projects into the receiving flange 4.1 and abuts against the edge of the central opening 10 in the sealing disc 7. At this point, the cannula protective cap 9 is such that at least the tip of the cannula 5 is tightly surrounded by the substance of the cannula protective cap 9, so that the cannula 5 is pierced into it during the installation of the cannula protective cap 9. Is formed in. Corresponding to FIG. 1, the cannula protective cap 9 can be wholly or partly made of a suitable material. On the other hand, it is most convenient for the embodiment according to FIG. 2 in which the cannula protective cap 9 is made of a hard-resilient technical material and is hollow on the inside. And
On the other hand, the hollow space surrounding the cannula 5, at least in the region of the cannula tip, is filled with a soft elastic, dense technical material, which is marked 11 in FIG. This allows soft elastic technical materials to be selected with optimum density, while hard-flexible technical materials are better suited to retain the mechanical influence from the external conditions.

However, there is likewise the possibility of first closing the syringe with the tip cap 12 releasably mounted on the closure 4. To that end, the tip cap 12 is provided with an axially aligned journal 12.1, which projects into the passage hole of the closure 4 provided for receiving a cannula. If the sealing disc 7 already has a central opening 10 from the beginning,
The journal 12.1 may extend through the sealing disc 7, with the free end of itself (12.1) abutting against the inner edge of the opening 10. On the other hand, if the closing disc 7 is first pierced by the end of the needle 5 mounted on the closure 4, the journal 12.1 ends just before the closing disc 7, as is apparent from FIG. In each case, the closure 4 comprises a connecting neck 13 for attachment of the cannula 5 carrying a needle sleeve 14. In FIG. 5, the syringe is depicted with a needle 5 attached.

6 to 8 show the so-called two-chamber syringe,
The syringe is additionally provided with a central plug 15, the chamber 16 between the syringe piston 3 and the central plug 15 serving for receiving the solvent. The chamber 17 on the cannula side is not melted,
Mostly it contains the active substance in freeze-dried form. In addition, the syringe cylinder 1 is a bypass that allows passage of solvent from the rear chamber 16 to the cannula-side chamber 17.
Has 18. The syringes as described above are pre-packed and sold as so-called finished syringes, the freeze-vacuum drying being carried out directly in the syringe. To that end, the closure 4 is provided with a through-going boring 19 which is connected to the receiving flange 4.1 and runs radially, the closure 4 having at least two locking positions on the syringe cylinder 1. There is.
In the first locking position in the direction of application of the closure 4 on the syringe cylinder 1, a throughbore 19 is connected to the chamber 17 on the cannula side, so that the solvent freed during freeze-vacuum drying is It can come out through the passage hole 19. After the end of the freeze-vacuum drying, the closure 4 is brought into the second locking position, in which the syringe cylinder 1 has its front side abutting the sealing disc 7 and the passage bore 19 of the syringe cylinder 1. It is covered by the outer covering surface.

In order to ensure a continuous transfer of the solvent from the rear chamber 16 into the chamber 17 on the cannula side, the male rod 2.1 and the finger support 6 are provided on the side where the piston rod 2 is directed towards the syringe piston 3. Equipped with a corresponding female screw. This causes the syringe piston 3 to be moved forward only by rotation of the piston rod 2 until the screw 2.1 of the piston rod 2 is released from the finger support 6. On the other hand, the side of the piston rod 2 facing away from the syringe piston 3 has a smaller diameter which allows the rod to move freely, so that it is subsequently present in molten form. Administration of the agent can be conventional.

A protective cap 20 may be placed over the closure 4, in particular as shown in FIG. 9, to ensure that the pre-filled finished syringe is in its original closed state. The protective cap 20 encloses the closure 4 in a form-fitting manner, the protective cap 20 carrying on its side facing the finger support 6 a clamping ring 20.1. The tightening ring 20.1 is connected to the protective cap 20 via a thin separating web, which is not depicted in detail in the drawing, and is permanently released on the closure 4 when it is permanently attached. It is connected to the. There, the syringe can only be opened on the cannula side, but not closed again, by removing the protective cap 20 on the separating web configured as a potential break. The protective cap 20 may carry an axially aligned journal 20.1 therein, which closes the cannula opening of the closure 4, so that the protective cap 20 simultaneously serves as a tip cap.

[Advantages of the Invention] The syringe as described at the beginning can be assembled with less difficulty and more easily than the components that are easily manufactured,
Furthermore, the individual components of the respectively required application and the correspondingly modified shape of the embodiment can likewise be used.

[Summary] A medical injector comprises a syringe cylinder (1), at least one syringe piston (3) movable in the cylinder via a piston rod (2), and further a cannula for the syringe piston (1). It comprises a side closure (4) and a finger support (6) at the end of the syringe cylinder (1) opposite the closure (4). Syringe cylinder (1)
As a cylindrical tube, which at least at the cannulated end has a ring flange (1.1) which is radially outward for the closure (4). The protruding protrusion is formed.
The ring flange (1.1) is in the axial direction on the front side,
Abutting against a flat cylindrical sealing disk (7) made of a relatively softly tuned rubber elastic industrial material,
The disc fits into the receiving flange (4.1) of the closure (4) and seals the syringe cylinder (1) against the closure (4). (Fig. 1)

[Brief description of drawings]

1 shows the object of the invention of the first embodiment with a cannula affixed in the closure and an attached cannula protection cap, and FIG. 2 comprises a modified cannula protection cap. FIG. 1 shows the object of FIG. 1, FIG. 3 shows the object of FIG. 1 but with an attached tip cap, and FIG. 4 shows the object of FIG. FIG. 5 is the subject of FIGS. 3 and 4 but with a cannula attached, FIG. 6 shows a variant of implementation suitable for freeze vacuum drying in the freeze vacuum drying position, FIG. Figure 6, but with a fully seated closure after freeze-vacuum drying, Figure 8 shows another configuration of the syringe of Figures 6 and 7, The figure shows a syringe having a shape corresponding to that of FIG.
With an original closure. [Explanation of symbols] 1 …… syringe cylinder 1.1 …… ring flange 2 …… piston rod 2.1 …… male thread 3 …… syringe piston 4 …… closed part 4.1 …… reception flange 5 …… cannula 6 …… finger support 7 …… Sealing disk 8 …… Ring flange 9 …… Cannula protection cap 10 …… Central opening 11 …… Industrial material 12 …… Tip cap 12.1 …… Journal 13 …… Connection neck 14 …… Needle sleeve 15 …… Central plug 16, 17 …… Chamber 18 …… Bypass 19 …… Passage hole boring 20 …… Protective cap 20.1 …… Tightening ring 20.2 …… Journal

 ─────────────────────────────────────────────────── ─── Continuation of the front page (56) References JP-A-52-58285 (JP, A) Actually open 2-49540 (JP, U) Actually open 1-68055 (JP, U) Actually open 58- 126839 (JP, U) Japanese Patent Publication Sho 51-13954 (JP, B2)

Claims (5)

[Claims] 1. A syringe for medical use, comprising a syringe cylinder (1).
And at least one syringe piston (3) movable in the cylinder by means of a piston rod (2), and a cannula-side closure (4) for the syringe cylinder (1).
And a finger support (6) at the end of the syringe cylinder (1) opposite the closure, the syringe cylinder (1) being configured as a cylindrical tube, At its axial end, the tube bears against a flat cylindrical sealing disc (7) made of a relatively soft rubber elastic material, which disc fits into the receiving flange (4.1) of the closure (4). Is inset,
A syringe for sealing a syringe cylinder (1) against a closure (4), said syringe cylinder (1) having a ring flange (1.1) at least at its cannula end, the ring flange (1.1) For the closure (4),
It is a locking projection that protrudes outward in the radial direction, and the closure (4) is releasably attached to the tip cap (1
Closed in 2), the cap comprises a closure (4)
With an axially oriented journal (12.1) protruding into the throughbore provided for receiving the cannula (5) and the sealing disc (7) with a central opening (10) And the free end of the journal (12.1) is in close contact with the inner edge of the opening (10). 2. A syringe according to claim 1, wherein the closure (4) comprises a connecting neck (13) for the attachment of a cannula (5) with a needle sleeve (14). A syringe characterized by being. 3. Syringe according to claim 1, as a complete prefilled syringe additionally provided with a central plug (15), for receiving a solvent. Chamber (16) between piston (3) and central plug (15)
And the cannula-side chamber (17) contains the active substance in a freeze-dried, undissolved form, and the syringe cylinder (1) is inserted into the cannula-side chamber (17). A bypass (18) for the passage of solvent, the closure (4) having at least two locking positions on the syringe cylinder (1) and receiving A through hole (19) connected to the flange (4.1) and running in the radial direction, wherein the through hole (19) is fitted with the closure (4) on the syringe cylinder (1) In a first locking position in the direction, the syringe cylinder (1) is in a second locking position which is connected to the cannula-side chamber (17) and the front side of the syringe cylinder (1) abuts the sealing disc (7). ) Outer cover surface Syringe according to claim. 4. The syringe according to claim 3, wherein the piston rod (2) has a male screw (2.1) on the side facing the syringe piston (3) and the finger support (6) corresponds to the female screw. Provided with threads, on the other hand, the side of the piston rod (2) opposite the syringe piston (3) has a relatively (smaller) diameter which allows its own free movement A syringe characterized in that. 5. The syringe according to any one of claims 1 to 4, wherein a protective cap (20) is placed on the closing part (4), and the cap is provided on the closing part (4). 4) form-connectingly surrounds, the protective cap (20) carrying a clamping ring (2.1) on the side facing the finger support (6), which ring is provided via a thin separating web. Connected to the protective cap (20), in a fully seated state, irreversibly connected to the closure (4), the protective cap (20) being inwardly, axially Syringe, characterized in that it carries a trimmed journal (20.2) which closes the cannula opening of the closure (4).