JPH0496762A - Therapeutic injector - Google Patents

Abstract

PURPOSE: To assemble an injector without any difficulty (quickly) by forming a lock projection projecting outward in the radial direction for a sealing part in a flange, bringing them in contact with a flat, cylinder-shaped, sealing disc whose front face side in the axial direction is composed of a rubber elastic industrial material comparatively softly adjusted, fitting the disc in a receiver flange for the sealing part, and sealing an injector cylinder in relation to the sealing part. CONSTITUTION: An injector cylinder 1 is constituted of a cylinder tube and the tube is provided with a ring flange 1.1 in a cannula side end part. The ring flange 1.1 which has a lock projection for a sealing part 4 projected outward in the radial direction is brought into contact with a flat, cylinder-shape, sealing disc 7 whose front face in the axial direction is composed of a rubber elastic (flexible) industrial material comparatively softly adjusted. The sealing disc 7 is fitted into a receiver flange 4.1 in the sealing part and seals the cylinder 1 to the injector in relation to the sealing part 4.

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial Application] The present invention relates to a medical syringe, which comprises a syringe cylinder, at least one syringe piston movable in the cylinder using a piston rod, and a syringe cylinder. a cannula-side closure for the syringe cylinder and a finger support at the end of the syringe cylinder opposite the closure.

[Prior Art and Problems to be Solved by the Invention] Syringes as described above are known and are available on the market in many embodiments. However, these syringes are assembled from many single components (parts), which are often made using wasteful manufacturing methods, thereby increasing the cost for a syringe that is only used once. It has the disadvantage of being extremely high.

A syringe as mentioned at the outset can be assembled easily (quickly) with fewer and more easily produced components and, moreover, can be adapted to the respective required use and correspondingly modified shape of the embodiment. The problem underlying the invention is to design the individual components in such a way that it is possible to use them in the same way.

According to the invention, the syringe cylinder is constituted by a cylindrical tube having at least one ring-shaped flange at its cannula-side end, which flange is provided for the closure part. forming a locking projection projecting outward in the radial direction, which abuts on its front side in the axial direction a flat cylindrical sealing disc made of a rubber-elastic industrial material adjusted in this way, which disc This problem is solved by sealing the syringe cylinder against the closure.

The essence of the advantages achieved by the invention can be summarized as follows:
A relatively simple cylindrical tube made mainly of glass (
There is a possibility that it can be used as a base body for a syringe that can be easily cut to the desired extent from a long tube. By melting the glass tube on the front side for the treatment of cut surfaces with sharp edges, a ring flange provided on the front side can be constructed at the same time.

Following this, the closure adapted to the particular application can be put on and fitted (locked) without any special adaptations being required.

In a first embodiment of the invention, the closure may be provided with a firmly affixed cannula and carry a radially outwardly directed ring [shaped coflange]. A cannula protection cap is placed on the flange and surrounds the cannula, the end of the cannula pointing towards the syringe cylinder protruding into the receiving flange and engaging the central opening in the sealing disc. It touches the edge. In the embodiment,
The syringe is already completely (finished) for use (utilization)
made so that for use the cannula protective cap only has to be removed, and
Insofar as already prefilled finished syringes are concerned, subsequently only the substance to be used has to be drawn up [into the syringe]. In this case, in an expedient refinement, the cannula protective cap is made of a hard-flexible technical material and is hollow on the inside, the hollow space surrounding the cannula being at least in the area of the cannula tip. It is planned (intended) to be filled with a soft, flexible, and airtight industrial material.
It's good that it has been done. In this way, a suitable protection of the cannula is obtained and at the same time it is ensured that the cannula is sealed with its own tip (without risk of damage to its own tip).

However, the closure is also releasably closed with a tip cap affixed thereto, the cap being provided with an axially oriented journal, the journal being in the cannula of the closure. Projection into a throughbore provided for reception can also be envisaged. In this case, the free end of the journal may protrude at most up to the sealing disk, or the sealing disk may be provided with a central opening and the free end of the journal may rest against the inner edge of the opening.

Furthermore, within the framework of the invention, the closure can also be provided with a connecting neck for attachment of a cannula with a needle sleeve. The needle is then placed on the connection neck after removal of the tip cap.

the syringe is configured as a prefilled finished syringe, the [finished] syringe is provided with a central stopper, and the syringe is provided with a central stopper;
The chamber between the syringe piston and the central stopper for receiving the solvent and the chamber on the cannula side contain the active substance in unmelted and lyophilized form and in which case the syringe If the cylinder has a bypass for the passage of the solvent into the chamber on the cannula side, it is further provided within the framework of the invention that the closure has at least two locking positions on the syringe cylinder. , and [the closure] is provided with a radially running throughbore connected to the receiving flange, the throughbore being in the direction of attachment (fastening) of the closure on the syringe cylinder. Connected to the chamber on the cannula side in the first locking position,
the second, where the front side of the syringe cylinder abuts the sealing disc;
In the locked position, it is intended to be covered by the outer covering surface of the syringe cylinder. in this case,
Insofar as the closure is in its first locking position, there is a connection to the outside of the chamber on the cannula side via the two-pass bore, so that the melted form into the chamber The resulting active substance can be freeze-vacuum dried via a through-hole. Subsequently, said chamber is closed in a sterile manner by simply further pressing the closure into the second locking position.

In such a syringe, the piston rod may be provided with a male thread on the side facing the syringe piston and the finger support with a corresponding female thread, while the side of the piston rod opposite the syringe piston may be provided with a male thread on the side facing the syringe piston. It has a relatively small diameter that allows free movement of the. The syringe piston can therefore only be moved from its starting position to the cannula end by a rotational movement of the syringe piston, which automatically limits the speed of movement of the piston.

This ensures that the solvent is slowly introduced into the antechamber containing the active substance.

The syringe piston was then melted only when the piston rod screw was released from the finger support.
For utilization (dosing) of the active substance, it can only be moved by pressure onto the piston rod.

Finally, within the scope of the invention, a protective cap is placed on the closure, which encloses the closure in a form-fitting manner, with the protective cap being directed towards its own finger support. carries a tightening ring on the side, which ring is connected to the protective cap via a thin separating web and irreleasably connected to the closure in the fully seated state, and in this case: The protective cap may carry an axially aligned journal on the inside, which journal is intended to close the cannula opening of the closure. The integrity of the protective cap then ensures that the contents of the syringe are still in their original sterile state.

[Embodiments] In the following, the invention will be explained in detail using embodiments illustrated in the drawings.

The illustrated medical syringe consists of a syringe cylinder 1 and at least one syringe piston 3 movable in the cylinder by means of a piston rod 2 . The syringe cylinder 1 is equipped at one end with a closure 4, which serves at the same time to receive a cannula 5, while at the other end a conventional finger support 6 is arranged.

In detail, the syringe cylinder 1 is constructed as a cylindrical tube, the protective tube having a ring flange 1, 1 at its cannula-side end. The ring flange 1.1 forms a latching projection for the closure part 4 which projects radially outwards, and has a rubber-resilient (flexible) industrial material adjusted in accordance with the comparative conditions on the front side in the axial direction. It rests on a flat cylindrical sealing disc 7 made of material. The sealing disc 7
is fitted into the receiving flange 4.1 of the closure 4 and seals the syringe cylinder l against the closure 4. In the embodiment depicted in FIGS. 1 and 2, the closure 4 is provided with a tightly attached (embedded) cannula 5, the closure 4 also having a radius of It carries a ring flange 8 directed outward in the direction. The ring flange 8 serves as a locking fit for a cannula protection cap 9 surrounding the cannula 5. The end of the cannula 5 facing the syringe cylinder 1 then projects into the receiving flange 4.1 and rests against the edge of the central opening 10 in the sealing disc 7.

In this case, the cannula protective cap 9 is such that at least the tip of the cannula 5 is tightly surrounded by the substance of the cannula protective cap 9, and the cannula 5 is attached to the cannula protective cap 9.
It is formed so as to pierce [inside] the cap when Corresponding to FIG. 1, the cannula protective cap 9 can then consist entirely or partially of a material suitable for this purpose. By contrast, more advantageous is usually the embodiment of FIG. 2, in which the cannula protective cap 9 is made of a hard-flexible (resilient) technical material and the inside is composed of a hollow structure,
On the other hand, the hollow space surrounding the cannula 5 is filled, at least in the area of the cannula tip, with a soft, flexible (elastic) and dense engineered material, which material (space) is marked 11 in FIG. ing. This allows soft-flexible engineering materials to be selected with optimal density, while hard-flexible engineering materials are better suited to retain mechanical influences from external conditions. There is.

However, there is also the possibility of first closing the syringe using a tip cap 12 releasably placed on the closure 4. To this end, the tip cap 12 is provided with an axially arranged journal 12.1, which projects into a passage bore of the closure 4, which is provided for receiving a cannula. If the sealing disk 7 is already provided with a central opening 1o from the beginning, the journal 12.1 can extend through the sealing disk 7, with its free end (12,1) touching the inner edge of the opening 10. It may be in close contact with the part. On the other hand, if the sealing disc 7 is pierced for the first time by the end of the needle 5 resting on the closure 4, the journal 12
．． J ends just before the sealing disc 7, as is clear from FIG. In each case, the closure 4 is provided with a connecting neck 13 for the attachment of a cannula 5 carrying a needle sleeve 14. In FIG. 5, the syringe is depicted with a needle 5 attached.

6 to 8 show a so-called double-barrel syringe, which is additionally equipped with a central stopper 15, the chamber I6 between the syringe piston 3 and the central stopper 15 containing a solvent. This will help in acceptance. The cannula-side chamber 17 contains the active substance in undissolved, usually freeze-vacuum dried form. Furthermore, the syringe cylinder 1 is connected to the rear chamber 1.
It has a bypass 18 that allows the passage of solvent from 6 to the chamber 17 on the cannula side. Such a syringe is sold pre-packed as a so-called finished syringe, in which case:
Freeze-vacuum drying is carried out directly in the syringe. for that,
The closure part 4 is connected to the receiving flange 4.1 and is provided with a radially running through bore 19, the closure part 4 having at least two locking positions on the syringe cylinder 1. . In the first locking position in the mounting direction of the closure 4 on the syringe cylinder l, the passage bore 1
9 is connected to the chamber 17 on the cannula side, so that the solvent freed during the freeze-vacuum drying is passed through the borehole 19.
It can come out through. After the end of the freeze-vacuum drying, the closure 4 is brought into a second locking position, in which the syringe cylinder l rests on the front side against the sealing disc 7 and the passage bore 19 is inserted into the syringe cylinder l. Covered by an outer covering surface.

In order to ensure a continuous transfer of the solvent from the rear chamber 16 into the chamber 17 on the cannula side, the piston rod 2 has an external thread 2.1 on the side facing the syringe piston 3 and a finger support. 6 is provided with a corresponding female thread. By this, the syringe piston 3 is attached to the screw 2 of the piston rod 2.
．． 1 is moved forward only by rotation of the rod until it is released from the finger support 6. In contrast, the side of the piston rod 2 opposite the syringe piston 8 has a relatively (smaller) diameter that allows free movement of the rod, so that it can be subsequently melted. Administration (application) of the active substance present in form can take place in the conventional manner. In order to in particular ensure that the pre-filled finished syringe remains in its original closed state, a protective cap 2 is placed on the closure 4, as is clear from FIG.
It is okay if 0 is placed on it.

The protective cap 20 encloses the closure 4 in a form-locking manner, with the protective cap 20 surrounding the closure 4 by its own finger support 6.
On the side facing towards, it carries a tightening ring 20.1. The clamping ring 20.1 is connected to the protective cap 20 via a thin separating web, which is not shown in detail in the drawing, and is irreleasably connected to the protective cap 20 when fully resting on the closure 4. connected to the closure. The syringe can then only be opened on the cannula side by removing the protective cap 2o at the separating web, which is configured as a predetermined failure point, but cannot be closed again. The protective cap 20 can then carry an axially aligned journal 20.1 on the inside, which journal closes the cannula opening of the closure 4, so that the protective cap 20 simultaneously acts as a tip cap. work.

[Effects of the invention] A syringe as mentioned at the outset can be assembled more easily (instantly) with fewer and more easily produced components and, moreover, can be used in each case and modified accordingly. The individual components of the shape embodiment can be used (fitted) in the same way.

[Summary] A medical syringe comprises a syringe cylinder (1) and at least one cylinder movable through the cylinder via a piston rod (2).
one syringe piston (3) and a further syringe piston (
1) and a finger rest (6) at the end of the syringe cylinder (1) opposite the closure (4). The syringe cylinder (1) is constructed as a cylindrical tube, and the protective tube has, at least at its cannula-side end, a ring flange (1,1), which flange is provided for the closure (4). A locking protrusion is formed that protrudes outward in the radial direction.

The ring flange (1, 1) abuts in the axial direction on the front side against a flat cylindrical sealing disc (7) made of a rubber-flexible (elastic) industrial material adjusted in this way, The disc is fitted into the receiving flange (4,1) of the closure (4) and seals the syringe cylinder (1) against the closure (4). (Figure 1)

[Brief explanation of the drawing]

FIG. 1 shows the subject of the invention in a first embodiment with a cannula stuck in the closure and a cannula protection cap attached, FIG. 2 with a modified cannula protection cap. 3 shows the object of FIG. 1 (albeit with an attached tip gap); FIG. 4 shows the object of FIG. 3 in a modified embodiment. , FIG. 5 shows the subject of FIGS. 3 and 4 but with a cannula attached, FIG. 6 shows a variant of the implementation suitable for freeze-vacuum drying, and FIG. 7 shows a variant of the implementation suitable for freeze-vacuum drying, and FIG. , the subject of Figure 6, but with a fully loaded closure after freeze-vacuum drying; Figure 8 shows an alternative configuration of the syringe of Figures 6 and 7; Although Fig. 9 shows a syringe with a shape corresponding to Fig. 3,
It shows one with an original closing part (shutter). [Explanation of symbols] 1...Syringe cylinder 1.1...Ring flange 2...Piston rod 2.1...Male thread 3... ...Syringe piston 4...Closing part 4.1...Receiving flange 5...Cannula 6...Finger support 7...Sealing disc (Washer) 8...
・Ring flange 9... Cannula protection cap 10...
・Central opening 11...Industrial material 12...Chip cap 12.1...Journal (pin) 13...
... Connection neck 14 ... Needle sleeve 15 ... Central plug 16.17 ... Chamber 18 ... Bypass 19 ... Passing hole 20... Protective cap 20.1... Tightening ring FIo, 1 FIG, 2 FIG, 3 20.2... Journal

Claims (1)

Claims: 1. A medical syringe comprising a syringe cylinder (1), at least one syringe piston (3) movable in the cylinder by means of a piston rod (2), and a syringe cylinder (1). ) with a cannula-side closure (4) for the syringe cylinder (1) and a finger rest (6) at the end of the syringe cylinder (1) opposite the closure.
), but at least the ring flange (
1.1), the flange forming a radially outwardly projecting locking projection for the closure (4) and axially
On the front side, it abuts a flat cylindrical sealing disc (washer) (7) made of a relatively soft and tuned rubber-elastic industrial material, which disc is connected to the closure part (4).
A syringe, characterized in that it is fitted into a receiving flange (4.1) of ), sealing the syringe cylinder (1) against the closure (4). 2. A syringe according to claim 1, in which the closure (4) is provided with a tightly affixed cannula (5) and directed radially outwards. It carries a ring flange (8), on which is a cannula protection cap (9) surrounding the cannula (5).
) of the cannula (5),
characterized in that the end directed towards the syringe cylinder (1) projects into the receiving flange (4.1) and abuts the edge of the central opening (10) in the sealing disc (7). Syringe. 3. The syringe according to claim 2, in which the cannula protective cap (9) is made of a hard and flexible industrial material and is hollow on the inside;
A syringe, characterized in that the hollow space surrounding the cannula (5), at least in the region of the cannula tip, is constructed using a soft, flexible, sealed engineering material. 4. A syringe according to claim 1, in which the closure (4) is closed with a releasably attached tip cap (12), which cap is attached to the closure (4).
), characterized in that it is equipped with an axially oriented journal (pin) (12.1) projecting into a passage bore provided for receiving a cannula (5). 5. Syringe according to claim 4, characterized in that the free end of the journal (12.1) projects at most as far as the sealing disc (7). 6. A syringe according to claim 4, in which the sealing disc (7) is provided with a central opening (10) and the free end of the journal (12.1) is located at the inner edge of said opening (10). A syringe characterized by close contact. 7. In the syringe according to claims 1 and 4 to 6, the closure part (4) comprises a needle sleeve (14).
Syringe characterized in that it is equipped with a connecting neck (13) for the attachment of a cannula (5) with a. 8. Syringe according to claim 1 as a prefilled finished syringe, additionally provided with a central stopper (15), in which case a syringe piston (3) for receiving the solvent ) and a chamber (16) between the central stopper (15);
The cannula-side chamber (17) contains the active substance in unmelted, freeze-vacuum dried form, and the syringe cylinder (1) injects the solvent into the cannula-side chamber (17). With a bypass (18) for passage (transition), the closure (4) is connected to the syringe cylinder (
1) with a through bore (19) having at least two locking positions on the top and running radially into the receiving flange (4.1), with
The passage bore (19) is connected to the chamber (17) on the cannula side in the first locking position in the direction of installation of the closure (4) on the syringe cylinder (1), and is connected to the chamber (17) on the cannula side. A syringe, characterized in that it is covered by the outer covering surface of the syringe cylinder (1) in the second locking position, in which the front side of the syringe abuts the sealing disc (7). 9. The syringe according to claim 8, wherein the piston rod (2) has a male thread (2.1) on the side facing the syringe piston (3), and the finger support (6) has a corresponding female thread. and, on the other hand, the side of the piston rod (2) opposite the syringe piston (3) has a relatively small diameter to allow its free movement. A syringe featuring: 10. The syringe according to any one of claims 1 and 4 to 9, wherein a protective cap (20) is placed on the closure part (4), and the cap is attached to the closure part (4). (4) in a form-fitting manner, the protective cap (20) carrying on the side facing the finger support (6) a tightening ring (2.1), which ring has a thin separating web. is connected to the protective cap (20) via the protective cap (20), and in the fully loaded state is irreleasably connected to the closure (4), and the protective cap (20) is A syringe characterized in that it carries an axially aligned journal (20.2), which journal closes the cannula opening of the closure (4).