JPH0871122A - Medicinal liquid container with communicating means - Google Patents

Abstract

PURPOSE: To provide a medicinal liquid container with a communicating means with which an operation is simple and rapid sterile transfer is possible even if this container is a medicinal liquid container with small rubber plugs. CONSTITUTION: A pump chamber 32 is formed between a pair of pricking needles 30A and 30B. Both pricking needles 30A and 30B are pricked into the rubber plugs 5a, 6a of a vial 5 and the medicinal liquid container 6 for mixed injection and thereafter, a container holder 2 in which the vial 5 is housed and fixed is vertically moved. As a result, the medicinal liquid L in the vial 5 is forcibly fed into the medicinal liquid container 6 for mixed injection by a pump.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a drug solution container with a communicating means for aseptically transferring a drug solution from one drug solution container to another drug solution container.

[0002]

2. Description of the Related Art Conventionally, in medical institutions such as hospitals, an infusion solution may be obtained by transferring a drug solution contained in a drug solution container such as a vial into a mixed injection drug container. Such a transfusion operation is carried out by inserting the injection needle of the syringe into the rubber stopper of the vial to inhale the drug solution from the vial, then pulling out the injection needle, and then inserting the injection needle into the rubber stopper of the mixed injection drug container, It is made by co-injecting the drug solution.

[0003]

However, the transfusing operation using such a syringe requires a long working time, and there is a possibility that the chemical solution may be contaminated. In particular, when the vial is an extremely small container, the diameter of the part to be pierced by the rubber stopper becomes small, for example, about 3 mm, and a thick injection needle cannot be pierced. It takes a lot of time for the transfusion operation. Further, it takes skill to insert the injection needle into the rubber stopper, and the operation is troublesome.

[0004] On the other hand, conventionally, various drug solution containers with communication means for penetrating the puncture part of a double-ended needle into the two rubber plugs in a posture in which the rubber plugs of the two drug containers are opposed to each other and transferring the drug solution have been proposed. (For example, Japanese Patent Laid-Open No. 2-1277)
No. 3-37067, and No. 4-253863). However, as described above, when the vial is a small container, the piercing needle needs to be formed to have a small outer diameter because the pierced portion is small. In this case, in the double-headed needle transfusing tool of the prior art, since the inner diameter of the puncture portion is also small, the medicinal solution to be transfused cannot naturally flow down in the medicinal solution passage of the double-headed needle, and is forced to flow down by pumping. Even when it is used, the flow-down speed is remarkably slowed, and therefore the transfusion time is lengthened.

The present invention has been made in view of the above-mentioned conventional problems, and an object of the present invention is to provide a chemical solution container that has a small rubber stopper and can be used aseptically in a short time and with a simple operation. It is an object of the present invention to provide a drug solution container with a communication means capable of transferring.

[0006]

Means and Actions for Solving the Problems In order to achieve the above-mentioned object, a chemical solution container with a communicating means of the present invention is a chemical solution container whose mouth is sealed with a rubber stopper, and a container for storing and holding the chemical solution container. A holder, a communicating means mounted axially movably on the container holder, and a cap member provided with a top surface and a skirt for covering the communicating means and axially movably capped on the container holder. , A first puncture needle of the communication means is pierced into a rubber stopper of the drug solution container, and a second puncture needle of the communication means is pierced into a rubber stopper of another drug container so that the drug solution is transferred from the drug solution container to another drug container. A drug solution container with a communicating means capable of being transfused, wherein the communicating means is the first and second puncture needles of the first and second puncture needles.
And second and second pump walls each of which has a respective hub and axially faces each other of the puncture needles, and a pump which is formed between the pump walls and communicates with hollow portions of the puncture needles. A chamber and a check valve that suppresses the flow of fluid from the second puncture needle to the pump chamber, and the cap member is pushed against the container holder to move the communication means. It is provided with a pressing means for inserting the first puncture needle into the rubber stopper of the drug solution container.

In the present invention, first, the cap member is pushed into the container holder, and the first puncture needle is pierced through the rubber stopper of the drug solution container in the container holder. Subsequently, the cap member is removed, the second puncture needle is pierced through the rubber stopper of another drug container, and then the upper drug solution container is placed on the lower drug container with the second puncture needle facing downward. By moving up and down with respect to each other, the first and second pump walls approach and separate from each other, and the liquid medicine is sucked from the liquid medicine container into the pump chamber, and the sucked liquid medicine is forcibly pumped to the other medicine container. It Therefore, even if the puncture needle pierced in a small drug solution container is thin,
The drug solution can be transferred quickly.

In the present invention, the second pump wall is elastically deformable by resin elasticity so as to move forward and backward with respect to the first pump wall, and restores the contracted state of the pump chamber to the expanded state. It is preferable to have power.

Further, in the present invention, the container holder is movably held by engaging the communicating means at the non-piercing position where the cutting edge of the first puncture needle faces the rubber stopper of the drug solution container. And a guide portion that guides the communicating means in the axial direction with the communication means positioned in the radial direction of the container holder up to the piercing position where the blade tip of the first puncture needle pierces the rubber stopper of the drug solution container. Preferably.

Further, in the present invention, it is preferable that the communication means is mounted on the inner peripheral side of the container holder, while the cap member is mounted on the outer peripheral side of the container holder so as to be able to be pushed.

[0011]

An embodiment of the present invention will be described below with reference to the drawings. In FIG. 1, the drug solution container 1 with the communicating means is
A vial holder (container holder) 2, a communication means 3 and a cap (cap member) 4 are provided. The vial holder 2 is a cylindrical container having a bottom as a whole,
For example, a drug solution container such as the vial 5 is held and stored. The communicating means 3 is mounted on the inner peripheral side of the vial holder 2, while the cap 4 is mounted on the outer peripheral side of the vial holder 2. In addition, vial 5
Has a drug solution L, such as a multivitamin preparation, inside, and its mouth is sealed by a rubber stopper 5a shown by a broken line.

Next, each component will be described in detail. As shown in FIG. 2 (b), the vial holder 2 is provided with a vial fixing ridge 21 protruding inward from the cylindrical portion 20 and extending in the axial direction S of the vial holder 2.
They are integrally formed with a 90 ° pitch. These vial fixing ridges 21 are in contact with the outer peripheral surface of the vial 5 and hold the vial 5 at a predetermined position. As shown in FIG. 1, a guide portion 22 and a stopper portion 23, which will be described later, are connected to the upper portion of the vial fixing ridge 21.

Next, the structure of the communication means 3 which is the main part of the present invention will be described. The communication means 3 includes the first cutting edge 30.
A first puncture needle 30A having a and a second puncture needle 30B having a second cutting edge 30b are provided. The first and second puncture needles 30A and 30B are separate from each other and fixed to first and second hubs 31a and 31b integrally formed with the first and second pump walls 31A and 31B, respectively. Has been done. At the non-piercing position P1 of FIG. 1, the first puncture needle 30A has a blade edge 30a protruding downward and facing toward the center of the rubber stopper 5a. On the other hand, the second puncture needle 30B projects in a direction (upward) opposite to the first puncture needle 30A and faces the inner surface of the cap 4. In addition,
The axes C of the first and second puncture needles 30A and 30B, the vial holder 2 and the vial 5 coincide with each other.

The pump walls 31A and 31B are opposed to each other in the axial direction S, and the pump chamber 32 communicating with the hollow portions of the first and second puncture needles 30A and 30B is located between the walls 31A and 31B. Is formed. The second pump wall 31B is relatively thinner than the first pump wall 31A,
The resin elasticity makes it elastically deformable so as to move forward and backward with respect to the first pump wall 31A.
Has a restoring force to restore the pump chamber 32 from the contracted state to the expanded state as shown in FIG. The second pump wall 31B has a thick wall in the vicinity of the hub 31b and in the outer peripheral portion 31c, and is welded to the first pump wall 31A at the outer peripheral portion 31c.

A valve body 31d is formed integrally with the second pump wall 31B. As shown in FIG. 3A, the valve body 31d has a second puncture needle 30.
Check valve 3 for suppressing the flow of fluid from B to pump chamber 32
It forms part of 3. That is, the valve body 31
A valve body 34 made of, for example, a ball is movably accommodated in d, and the valve body 34 comes into contact with a valve seat 36 integrally formed with the second pump wall 31B, whereby the valve passage 3
5 is closed. A rib-shaped piece 37 for stabilizing the operation of the valve body 34 is provided on the valve body 31d.
It is integrally formed as shown in (c).

On the other hand, the first pump wall 31A in FIG. 1 is thicker and has higher rigidity than the second pump wall 31B, and constitutes a part of the cap-shaped communicating means frame 38. In the communication means frame 38, there are provided a cylindrical portion 38a continuously provided from the outer peripheral edge of the disk-shaped first pump wall 31A, and four guided portions projecting downward from the cylindrical portion 38a in the axial direction S. The part 38b is integrally formed. Guided part 38b
Is engaged with a pair of holding portions 24A and 24B protruding inward from the vial holder 2, and is held by the resin elasticity so as to be movable in both directions in the axial direction S. Further, each of the guided portions 38b is fitted into the groove-shaped guide portion 22 of the vial holder 2, and therefore, the guide portion 38b of FIG.
The guided portion 38b of (b) is positioned in the radial direction R of the vial holder 2 by the guide portion 22, and the blade tip 30a of the first puncture needle 30A of FIG. Axial direction S up to the piercing position P2 for piercing 5a
Will be guided to. The stopper portion 23 comes into contact with the guided portion 38b to prevent the communication means 3 from being pushed below the predetermined piercing position P2.

Next, the cap 4 will be described. In FIG. 1, the cap 4 includes a top surface 40 and a skirt 41, covers the communication means 3, and is capped on the vial holder 2 so as to be pushed in the axial direction S. Therefore, in the state before use in FIG. 1, the first and second puncture needles 30A and 30B of the communication means 3 and the vial 5 are stored in the vial holder 2 and the cap 4, and are contaminated by various bacteria in the air. It is supposed not to be done. The cap 4 is integrally provided with an engaged portion 41a that protrudes inward from the lower end of the skirt 41, and the engaged portion 41a is a pair that protrudes outside the vial holder 2. Is engaged with the engaging portion 25 of. By this engagement, the cap 4 is held at the position shown in FIG. 1 before use, and the cap 4 can be pushed in due to resin elasticity during use as shown in FIG. 2A. There is. In the cap 4, for example, a cylindrical pressing portion (pressing means) 42 is formed integrally with the skirt 41 in a concentric shape. The pressing surface 42a at the tip of the pressing portion 42 is close to (or adjacent to) the outer peripheral portion 31c of the communicating means 3 and faces the state before use in FIG. 1, that is, in the non-piercing position P1. Therefore, FIG.
As shown in (a), by pushing the cap 4 into the vial holder 2, the pressing portion 42 pushes the communication means 3 toward the depth of the vial holder 2 in the axial direction S to the piercing position P2.

The vial holder 2, the communication means 3 and the cap 4 are provided with the first and second puncture needles 30A, 30.
In addition to B being made of metal, it is made of a synthetic resin having flexibility and chemical resistance, such as polypropylene or polyethylene. The vial 5 is made of glass or synthetic resin.

Next, how to use the chemical liquid container 1 with the communicating means will be described. From the state of FIG. 1, first, the cap 4
When is pushed downward, the pressing surface 42a of the pressing portion 42 contacts the outer peripheral portion 31c of the communicating means 3, and the communicating means 3 is pushed from the non-piercing position P1 to the piercing position P2 of FIG. 2A. . At this time, in the communication means 3, the guided portion 38b is guided by the guide portion 22, and therefore, the central portion of the rubber stopper 5a of the vial 5 is accurately pierced without rotating the first puncture needle 30A. To do. Therefore, the first puncture needle 30A can be easily and quickly pierced into the rubber plug 5a even when the range in which the rubber plug 5a can be pierced, that is, the diameter of the part to be pierced is small. The rubber plug 5a due to the rotation of the puncture needle 30A (referred to as "coring")
The problem of can be avoided.

After the piercing operation, the cap 4 is removed, and then the second puncture needle 30B shown in FIG. 4 is pierced through the rubber stopper 6a of the mixed injection drug container 6 such as a drip container. Thus, the rubber stoppers 5a of the vial 5 and the mixed injection drug container 6 are
6a are pierced by the first and second puncture needles 30A, 30B in a posture in which they face each other, whereby the inside of the vial 5 and the inside of the mixed injection drug container 6 communicate with each other via the communication means 3.

After the communication, the second puncture needle 3 as shown in FIG.
The vial holder 2 is reciprocated up and down with OB facing downward. Due to this reciprocal movement, the pump chamber 32 repeatedly contracts and expands. When the pump chamber 32 expands,
Since the valve body 34 of FIG. 3A is pressed against the valve seat 36 to prevent the fluid from flowing from the mixed injection drug container 6 of FIG. 4 to the pump chamber 32, the negative pressure in the pump chamber 32 is prevented. The drug solution L in the vial 5 is sucked into the pump chamber 32. on the other hand,
When the pump chamber 32 contracts, as shown in FIG.
The check valve 33 is opened, and the chemical liquid L in the pump chamber 32 in FIG.
Flows into the mixed injection drug container 6. The mixed liquid into which the chemical liquid L has flowed is connected to a not shown ring fluid tube or the like and used as a ring fluid.

As described above, the liquid medicine container 1 with the communicating means is provided.
Causes the liquid L to be forcibly transferred by the pump,
Unlike the natural flow-down, even if the diameter of the first puncture needle 30A is small, that is, even if the rubber stopper 5a of the vial 5 is small, the mixed injection of the drug solution L can be performed quickly. Also,
In this way, mixed injection can be performed quickly, and the possibility that the chemical liquid L is contaminated is reduced.

Further, in this embodiment, as shown in FIG.
The vial holder 2 is formed into a bottomed cylindrical shape for accommodating the vial 5, and the vial holder 2 is equipped with the communication means 3 and the cap 4. Therefore, in a state where the communication means 3 and the vial 5 are set. Can be transported and stored. Therefore, unlike the conventional method of performing mixed injection using a syringe, the mixed injection operation can be performed immediately when the drug solution L is mixed.

In this embodiment, the puncture needles 30A, 30
Since the pump chamber 32 is configured by the pump walls 31A and 31B to which B is fixed, and the second pump wall 31B elastically deforms to exert a restoring force, the structure of the pump is simplified. However, the present invention does not limit the structure of the pump, and the pump includes a pair of puncture needles 30A, 30A.
Alternatively, a bellows-shaped flexible tubular portion may be formed between the pair of pump walls 31A and 31B to which B is fixed.
When the restoring force of the flexible tubular portion is weak, a coil spring may be integrally molded in the flexible tubular portion.

Further, although the valve element 34 made of a ball is adopted in the present embodiment, the present invention does not limit the shape and structure of the check valve 33. For example, the valve element 34 is shaped like a tongue piece. Alternatively, it may be formed of a bird's beak-shaped silicon rubber or the like.

On the outer periphery of the upper part of the vial holder 2,
A seal ring may be attached to improve the sealing property between the cap 4 and the vial holder 2 so that germs may be reliably prevented from entering the drug solution container 1 with the communicating means.

[0027]

As described above, according to the present invention,
Even if the rubber stopper of a drug solution container such as a vial is small, and therefore the diameter of the puncture needle is small, the drug solution can be forcibly pressure-fed by the pump provided in the communication means, so that the drug solution can be quickly transferred. it can. Furthermore, since the communication means and the cap can be stored in the container holder that stores and holds the drug solution container such as the vial, immediately,
The transfer operation can be started, and the transfer operation can be performed more quickly than when a syringe is used. Also, until just before inserting the second puncture needle into another drug container,
Since the second puncture needle is hygienically protected by the cap, there is less risk of the chemical liquid being contaminated.

When the pump wall itself has a restoring force as in the second aspect, the structure of the pump is simplified.

Further, as described in claim 3, if the communicating means to which the first puncture needle is fixed is axially guided and movable while being positioned in the radial direction with respect to the container holder, the liquid medicine container Even if the rubber plug is small, the rubber plug can be pierced easily and quickly, and the problem of coring does not occur.

[Brief description of drawings]

FIG. 1 is a vertical cross-sectional view of a chemical liquid container with a communicating means in a non-piercing state showing an embodiment of the present invention.

FIG. 2 (a) is a vertical cross-sectional view of a chemical liquid container with a communicating means in a pierced state, and FIG. 2 (b) is a cross-sectional view taken along line bb of (a).

FIG. 3 is an enlarged sectional view showing a check valve.

FIG. 4 is a vertical cross-sectional view of a drug solution container with a communicating means showing an injection method.

[Explanation of symbols]

 1: Chemical solution container with communication means 2: Container holder 3: Communication means 4: Cap member 5: Chemical solution container 5a: Rubber stopper 6: Mixed injection chemical container 6a: Rubber stopper 22: Guide part 24A, 24B: Holding part 30A: No. First puncture needle 30B: Second puncture needle 31A: First pump wall 31B: Second pump wall 31a: First hub 31b: Second hub 32: Pump chamber 33: Check valve 40: Top surface 41: skirt 42: pressing means P1: non-piercing position P2: piercing position S: axial direction

 ─────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor Tadatoshi Uchida 3-9-3 Honjo-nishi, Kita-ku, Osaka City Nissho Co., Ltd.

Claims (4)

[Claims] 1. A drug solution container whose mouth is sealed with a rubber stopper,
A container holder for accommodating and holding the drug solution container, a communication means axially movably attached to the container holder, and a top surface and a skirt for covering the communication means are provided in the container holder movably in the axial direction. Consisting of a capped cap member,
The first puncture needle of the communication means is pierced into the rubber stopper of the drug solution container, and the second puncture needle of the communication means is pierced into the rubber stopper of the other drug container to transfer the drug solution from the drug solution container to the other drug container. A drug solution container with a communication means, which is capable of being transferred, wherein the communication means has first and second hubs of the first and second puncture needles, respectively, and the both puncture needles are provided. First and second pump walls facing each other in the axial direction of the needle, a pump chamber formed between these pump walls and communicating with the hollow portions of the both puncture needles, and the second puncture needle to the pump A check valve for suppressing the flow of fluid to the chamber, wherein the cap member is pushed into the container holder to move the communication means to move the first puncture needle into the rubber stopper of the drug solution container. Drug with communication means equipped with pressing means for piercing Container. 2. The second pump wall according to claim 1,
A liquid medicine container with a communicating means that is elastically deformable by resin elasticity so as to move forward and backward with respect to the first pump wall and has a restoring force that restores the contracted state of the pump chamber to the expanded state. 3. The container holder according to claim 1, wherein the container holder is engaged with the communicating means to move the communicating means at a non-piercing position where a blade edge of the first puncture needle faces the rubber stopper of the drug solution container. A holding portion for holding and a guide portion for guiding the communicating means in the axial direction with the communication means positioned in the radial direction of the container holder up to the piercing position where the blade tip of the first puncture needle pierces the rubber stopper of the drug solution container. A drug solution container with a communication means. 4. The chemical liquid container with the communicating means according to claim 1, wherein the communicating means is mounted on the inner peripheral side of the container holder, while the cap member is mounted on the outer peripheral side of the container holder so as to be pushed in.