JP3616144B2 - Chemical container with communication means - Google Patents

Description

[0001]
[Industrial application fields]
The present invention relates to a chemical solution container with communication means for aseptically transferring a chemical solution from one chemical solution container to another drug container.
[0002]
[Prior art]
2. Description of the Related Art Conventionally, in medical institutions such as hospitals, an infusion may be obtained by transferring a liquid medicine contained in a liquid medicine container such as a vial into a mixed liquid medicine container. In this transfer operation, the syringe needle is pierced through the rubber stopper of the vial and the liquid medicine is drawn from the vial. It is made by mixing the chemical solution.
[0003]
[Problems to be solved by the invention]
However, the transfer operation using such a syringe takes a long working time and may contaminate the chemical solution. In particular, when the vial is a very small container, the diameter of the pierced portion of the rubber stopper is as small as about 3 mm, for example, and a thick injection needle cannot be pierced. The transfer operation takes time. Further, skill is required to pierce the injection needle through the rubber stopper, and the operation is troublesome.
[0004]
On the other hand, various chemical liquid containers with communication means have been proposed in the past in which the rubber plugs of the two drug containers face each other and the puncture portion of the double-ended needle is inserted into the two rubber plugs to transfer the chemical liquid. (For example, refer to JP-A-2-1277, JP-A-3-37067, and JP-A-4-253863). However, when the vial is a small container as described above, since the pierced portion is small, it is necessary to make the outer diameter of the puncture needle small. In this case, in the prior art double-ended needle transfer device, the inner diameter of the puncture portion is also reduced, so that the transferred drug solution cannot naturally flow down in the drug solution passage of the double-ended needle and is forced to flow down by pumping. Even if it is made to flow, the flow-down speed becomes remarkably slow, and therefore the transfer time becomes long.
[0005]
The present invention has been made in view of the above-described conventional problems, and the purpose thereof is to aseptically transfer a chemical solution in a simple operation and in a short time even for a chemical solution container having a small rubber stopper. It is an object of the present invention to provide a chemical container with communication means that can be used.
[0006]
[Means and Actions for Solving the Problems]
In order to achieve the above object, the chemical container with communication means of the present invention comprises a chemical container having a mouth sealed with a rubber stopper, a container holder for storing and holding the chemical container, and an axial movement to the container holder. A communication means that is freely mounted, and a cap member that includes a top surface and a skirt that covers the communication means, and is crowned by the container holder so as to be movable in the axial direction, and the first puncture needle of the communication means is Communicating in which the chemical solution can be transferred from the chemical solution container to the other drug container by piercing the rubber plug of the drug solution container and the second puncture needle of the communication means inserted into the rubber plug of the other drug container A medical solution container with means, wherein the communication means has first and second hubs of the first and second puncture needles, and is opposed to each other in the axial direction of the both puncture needles. And the second pump wall and both of these pumps A pump chamber that is formed between the two puncture needles and communicates with the hollow portion of the both puncture needles, and a check valve that suppresses the flow of fluid from the second puncture needle to the pump chamber. There is provided a pressing means for moving the communication means by being pushed into the holder so that the first puncture needle is inserted into the rubber stopper of the drug solution container.
[0007]
In the present invention, first, the cap member is pushed into the container holder, and the first puncture needle is pierced through the rubber stopper of the chemical solution container in the container holder. Subsequently, after removing the cap member and inserting the second puncture needle into the rubber stopper of another drug container, the upper drug solution container is moved to the lower drug container with the second puncture needle facing downward. By moving up and down, the first and second pump walls approach and separate, and the chemical solution is sucked into the pump chamber from the chemical solution container, and the sucked chemical solution is forcibly pumped to the other drug container. The Therefore, even when the puncture needle pierced through the small drug solution container is thin, the drug solution is quickly transferred.
[0008]
In the present invention, the second pump wall can be elastically deformed so as to move forward and backward with respect to the first pump wall by resin elasticity, and has a restoring force for restoring the contracted pump chamber to the expanded state. It is preferable.
[0009]
In the present invention, the container holder is a holding portion that engages with the communication means and holds the communication means movably at the non-piercing position where the cutting edge of the first puncture needle faces the rubber stopper of the drug solution container. And a guide portion for guiding the communicating means in the axial direction in a state in which the communicating means is positioned in the radial direction of the container holder until the cutting edge of the first puncture needle pierces the rubber stopper of the drug solution container. Is preferred.
[0010]
In the present invention, it is preferable that the communication means is mounted on the inner peripheral side of the container holder, and the cap member is mounted on the outer peripheral side of the container holder so as to be able to be pushed.
[0011]
【Example】
Hereinafter, an embodiment of the present invention will be described with reference to the drawings.
In FIG. 1, a chemical container 1 with communication means includes a vial holder (container holder) 2, communication means 3, and a cap (cap member) 4. The vial holder 2 is a bottomed cylindrical container as a whole, and holds and stores a chemical solution container such as a vial 5. The communication means 3 is mounted on the inner peripheral side of the vial holder 2, while the cap 4 is mounted on the outer peripheral side of the vial holder 2. The vial 5 contains, for example, a drug solution L such as a general vitamin, and has a mouth sealed by a rubber stopper 5a indicated by a broken line.
[0012]
Next, each component will be described in detail.
A vial fixing ridge 21 protruding inward from the cylindrical portion 20 and extending in the axial direction S of the vial holder 2 is integrated with the vial holder 2 at a 90 ° pitch as shown in FIG. Is formed. These vial fixing ridges 21 are in contact with the outer peripheral surface of the vial 5 and hold the vial 5 in a predetermined position. As shown in FIG. 1, a guide portion 22 and a stopper portion 23 described later are connected to the upper portion of the vial fixing ridge 21.
[0013]
Next, the structure of the communication means 3 that is the main part of the present invention will be described.
The communicating means 3 includes a first puncture needle 30A having a first blade edge 30a and a second puncture needle 30B having a second blade edge 30b. The first and second puncture needles 30A and 30B are separate from each other and fixed to first and second hubs 31a and 31b formed integrally with the first and second pump walls 31A and 31B, respectively. Has been. The first puncture needle 30A is opposed to the blade tip 30a protruding downward, that is, toward the center of the rubber plug 5a, at the non-piercing position P1 in FIG. On the other hand, the second puncture needle 30B protrudes in the direction (upward) opposite to the first puncture needle 30A and faces the inner surface of the cap 4. Note that the axes C of the first and second puncture needles 30A and 30B, the vial holder 2 and the vial 5 coincide with each other.
[0014]
The pump walls 31A, 31B are opposed to each other in the axial direction S, and a pump chamber 32 communicating with the hollow portion of the first and second puncture needles 30A, 30B is formed between the walls 31A, 31B. ing. The second pump wall 31B is relatively thinner than the first pump wall 31A, and can be elastically deformed so as to move forward and backward relative to the first pump wall 31A by its resin elasticity. The pump chamber 32 has a restoring force for restoring from the contracted state to the expanded state of the pump chamber 32 as shown in FIG. In the second pump wall 31B, the vicinity of the hub 31b and the outer peripheral portion 31c are thick, and the outer peripheral portion 31c is welded to the first pump wall 31A.
[0015]
A valve body 31d is formed integrally with the second pump wall 31B. As shown in FIG. 3A, the valve body 31 d constitutes a part of a check valve 33 that suppresses the flow of fluid from the second puncture needle 30 </ b> B to the pump chamber 32. That is, a valve body 34 made of, for example, a ball is movably accommodated in the valve body 31d, and the valve body 34 comes into contact with a valve seat 36 formed integrally with the second pump wall 31B. The inner passage 35 is closed. In addition, a rib-like piece 37 for stabilizing the operation of the valve body 34 is integrally formed in the valve body 31d as shown in FIG.
[0016]
On the other hand, the first pump wall 31A in FIG. 1 is thicker and more rigid than the second pump wall 31B, and constitutes a part of the cap-shaped communication means frame 38. The communication means frame 38 has a cylindrical portion 38a continuously provided from the outer peripheral edge of the disk-shaped first pump wall 31A, and four guided members projecting downward in the axial direction S from the cylindrical portion 38a. The part 38b is integrally formed. The guided portion 38b is engaged with a pair of holding portions 24A and 24B protruding inward from the vial holder 2, and is held so as to be movable in both directions in the axial direction S by resin elasticity. . Each guided portion 38b is fitted into the groove-shaped guide portion 22 of the vial holder 2. Therefore, the guided portion 38b in FIG. In a state of being positioned in the radial direction R, the cutting edge 30a of the first puncture needle 30A in FIG. 2A is guided in the axial direction S to the piercing position P2 where the rubber stopper 5a of the vial 5 is pierced. In addition, the above-mentioned stopper part 23 contacts the guided part 38b, thereby preventing the communication means 3 from being pushed below the predetermined piercing position P2.
[0017]
Next, the cap 4 will be described.
In FIG. 1, the cap 4 includes a top surface 40 and a skirt 41, covers the communication means 3, and is covered with the vial holder 2 so as to be able to be pushed in the axial direction S. Therefore, in the state before use of FIG. 1, the first and second puncture needles 30A and 30B and the vial 5 of the communication means 3 are housed in the vial holder 2 and the cap 4 and are contaminated by germs in the air. Not to be. The cap 4 is integrally provided with an engaged portion 41 a that protrudes inward from the lower end of the skirt 41, and the engaged portion 41 a protrudes outward from the vial holder 2. Is engaged with the engaging portion 25. By this engagement, the cap 4 is held at the position shown in FIG. 1 before use, and at the time of use, the cap 4 can be pushed in by resin elasticity as shown in FIG. 2A. Yes. In the cap 4, for example, a cylindrical pressing portion (pressing means) 42 is integrally formed concentrically with the skirt 41. The pressing surface 42a at the tip of the pressing portion 42 faces the outer peripheral portion 31c of the communicating means 3 in proximity (or adjacent) to the state before use in FIG. 1, that is, the non-piercing position P1. Therefore, as shown in FIG. 2A, when the cap 4 is pushed into the vial holder 2, the pressing portion 42 pushes the communication means 3 toward the piercing position P <b> 2 toward the back in the axial direction S of the vial holder 2. .
[0018]
The vial holder 2, the communication means 3, and the cap 4 are flexible and chemical resistant, such as polypropylene and polyethylene, except that the first and second puncture needles 30A and 30B are made of metal. It is made of some synthetic resin. The vial 5 is made of glass or synthetic resin.
[0019]
Next, how to use the chemical container 1 with communication means will be described.
From the state of FIG. 1, first, when the cap 4 is pushed downward, the pressing surface 42a of the pressing portion 42 comes into contact with the outer peripheral portion 31c of the communicating means 3, and the communicating means 3 moves from the non-piercing position P1 to FIG. It is pushed to the piercing position P2 of a). At this time, in the communicating means 3, the guided portion 38b is guided by the guide portion 22, and therefore the central portion of the rubber stopper 5a of the vial 5 is accurately pierced without rotating the first puncture needle 30A. To do. Therefore, the first puncture needle 30A can be easily and quickly inserted into the rubber plug 5a even if the rubber plug 5a can be pierced, that is, the diameter of the portion to be pierced is small. The problem of cutting off the rubber stopper 5a (referred to as “coring”) due to the rotation of the puncture needle 30A can be avoided.
[0020]
After the piercing operation, the cap 4 is removed, and then the second puncture needle 30B shown in FIG. 4 is pierced through the rubber stopper 6a of the mixed injection drug container 6 such as an infusion container. Thus, the rubber stoppers 5a, 6a of the vial 5 and the mixed injection drug container 6 are pierced by the first and second puncture needles 30A, 30B in a posture facing each other, whereby the inside of the vial 5 and the mixed injection drug container 6 communicates with each other through the communication means 3.
[0021]
After the communication, the vial holder 2 is reciprocated up and down with the second puncture needle 30B directed downward as shown in FIG. By this reciprocation, the pump chamber 32 repeatedly contracts and expands. When the pump chamber 32 expands, the valve body 34 in FIG. 3A presses against the valve seat 36 to prevent fluid from flowing into the pump chamber 32 from the mixed drug container 6 in FIG. Therefore, the liquid L in the vial 5 is sucked into the pump chamber 32 due to the negative pressure in the pump chamber 32. On the other hand, when the pump chamber 32 contracts, as shown in FIG. 3 (b), the check valve 33 is opened, and the drug solution L in the pump chamber 32 of FIG. 4 flows into the mixed injection drug container 6. The mixed liquid into which the chemical liquid L has flowed is connected to a ring liquid tube (not shown) or the like and used as a ring liquid.
[0022]
In this way, since the chemical liquid container 1 with the communication means forcibly transfers the chemical liquid L by the pump, unlike the natural flow down, even if the diameter of the first puncture needle 30A is small, that is, the vial Even if the rubber plug 5a of 5 is small, the chemical solution L can be mixed and injected quickly. Moreover, since mixed injection can be performed quickly in this way, the possibility that the chemical liquid L is contaminated is reduced.
[0023]
Further, in this embodiment, as shown in FIG. 1, the vial holder 2 is formed in a bottomed cylindrical shape for housing the vial 5, and the communication means 3 and the cap 4 are attached to the vial holder 2, and therefore The communication means 3 and the vial 5 can be transferred and stored in a set state. Therefore, unlike the conventional method of performing co-infusion using a syringe, co-infusion operation can be performed immediately when the chemical solution L is co-injected.
[0024]
Further, in this embodiment, the pump wall 31A, 31B to which the puncture needles 30A, 30B are fixed constitutes the pump chamber 32, and the second pump wall 31B is elastically deformed to exert a restoring force. The structure of the pump becomes simple. However, the present invention does not limit the structure of the pump, and the pump has a bellows-like flexible cylindrical portion between the pair of pump walls 31A and 31B to which the pair of puncture needles 30A and 30B are fixed. It may be provided and formed. In addition, when the restoring force of the flexible tubular portion is weak, a coil spring may be integrally formed in the flexible tubular portion.
[0025]
Further, in the present embodiment, the valve body 34 made of a ball is adopted. However, the present invention does not limit the shape and structure of the check valve 33. You may form with a cage-like silicon rubber.
[0026]
Further, by attaching a seal ring to the outer periphery of the upper portion of the vial holder 2 and improving the sealing performance between the cap 4 and the vial holder 2, it is possible to reliably prevent germs from entering the chemical solution container 1 with communication means. May be.
[0027]
【The invention's effect】
As described above, according to the present invention, even when the rubber stopper of the drug solution container such as a vial is small and the diameter of the puncture needle is small, the drug solution is forcibly pumped by the pump provided in the communicating means. Therefore, the chemical solution can be quickly transferred. Furthermore, since the communication means and the cap can be stored in an assembled state in a container holder for storing and holding a chemical solution container such as a vial, the transfer operation can be started immediately, and the transfer operation compared to the case of using a syringe. Can be performed even more quickly. In addition, since the second puncture needle is hygienically protected by the cap until just before the second puncture needle is pierced into another drug container, the possibility of contamination with the chemical solution is reduced.
[0028]
Further, if the pump wall itself has a restoring force as in claim 2, the structure of the pump is simplified.
[0029]
Further, as in claim 3, if the communicating means to which the first puncture needle is fixed is positioned in the radial direction with respect to the container holder and can be moved while being guided in the axial direction, the rubber stopper of the chemical solution container Even if it is small, the rubber plug can be pierced easily and quickly and the problem of coring does not occur.
[Brief description of the drawings]
FIG. 1 is a longitudinal sectional view of a chemical container with communication means in one non-piercing state according to an embodiment of the present invention.
FIG. 2A is a longitudinal sectional view of a chemical solution container with communication means in a pierced state, and FIG. 2B is a sectional view taken along line bb of FIG.
FIG. 3 is an enlarged sectional view showing a check valve.
FIG. 4 is a longitudinal sectional view of a chemical solution container with communication means showing an injection method.
[Explanation of symbols]
1: Chemical container 2 with communication means 2: Container holder 3: Communication means 4: Cap member 5: Chemical liquid container 5a: Rubber plug 6: Mixed injection drug container 6a: Rubber plug 22: Guide portions 24A, 24B: Holding portion 30A: No. 1 puncture needle 30B: second puncture needle 31A: first pump wall 31B: second pump wall 31a: first hub 31b: second hub 32: pump chamber 33: check valve 40: top surface 41: Skirt 42: Pressing means P1: Non-piercing position P2: Piercing position S: Axial direction

Claims (5)

A chemical solution container whose mouth is sealed with a rubber stopper, a container holder for storing and holding the chemical solution container, communication means mounted on the container holder so as to be movable in the axial direction, and a top surface and a skirt covering the communication means And a cap member that is covered with the container holder so as to be movable in the axial direction. The first puncture needle of the communication means is pierced through the rubber stopper of the drug solution container and the second puncture needle of the communication means A chemical container with communication means that allows the chemical liquid to be transferred from the chemical container to the other chemical container by piercing the rubber stopper of the other chemical container,
The communication means has first and second hubs to which a second puncture needle separate from the first puncture needle and the first puncture needle is fixed , and both the puncture needles First and second pump walls that face each other in the axial direction, a pump chamber that is formed between these pump walls and communicates with the hollow portion of both puncture needles, and from the second puncture needle to the pump chamber And a check valve that suppresses the flow of fluid.
Said cap member, e Bei a pressing means for pierced first puncture needle by moving the communication means to the rubber stopper of the drug solution container by being pressed against the container holder,
The second puncture needle is covered with the cap member until just before the second puncture needle is pierced into the other drug container, and the cap member is pushed in so that the first puncture needle is inserted into the drug solution container. A chemical solution container with communication means that allows the second puncture needle to be pierced into the other drug container by removing the cap member after being pierced through the rubber stopper . 2. The second pump wall according to claim 1, wherein the second pump wall is elastically deformable so as to move forward and backward relative to the first pump wall by resin elasticity, and has a restoring force for restoring the contracted pump chamber to an expanded state. A chemical container with communication means. The container holder according to claim 1,
A holding portion that engages the communication means and movably holds the communication means at a non-piercing position where the cutting edge of the first puncture needle faces the rubber stopper of the drug solution container;
A communicating means having a guide portion for guiding the communicating means in the axial direction in a state where the communicating means is positioned in the radial direction of the container holder until the cutting edge of the first puncture needle penetrates the rubber stopper of the drug solution container With chemical solution container. 2. The chemical solution container with communication means according to claim 1, wherein the communication means is attached to the inner peripheral side of the container holder, while the cap member is attached to the outer peripheral side of the container holder so as to be pushed. 5. The check valve according to claim 1, wherein the check valve includes a valve seat and a valve passage formed in the second pump wall, and a valve body movably accommodated in the valve passage. A chemical container with communication means.

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