JPH08336926A - Oxygen barrier transparent packaging material and bag made of the same material - Google Patents

Abstract

PURPOSE: To provide a bag having not only excellent gas barrier properties (particularly oxygen barrier properties and transparency but also scarcely causing a pinhole even when a thick article lick an infusion bag is packaged and its molding material. CONSTITUTION: The bag is formed of an oxygen barrier transparent packaging material containing at least one gas barrier layer 1 made of an aluminum oxide- deposited nylon film 3 or a silicon oxide-deposited nylon film 3, used for packaging an article having substantially thickness and adapted to have the bottom of a gusset.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an oxygen-blocking transparent packaging material and a bag made of the packaging material. More specifically, it is excellent in transparency and barrier property against gases such as oxygen and has a large thickness. The present invention relates to a bag body in which pinholes are less likely to occur when an article is packaged and a forming material thereof.

INDUSTRIAL APPLICABILITY The present invention can be used, for example, for packaging medicines and foods, and is particularly suitable for use as an outer bag for a so-called infusion bag, which is obtained by filling a relatively large volume of injectable solution into a flexible plastic container. it can.

[0003]

2. Description of the Related Art Infusions, which are relatively large volume injections,
Conventionally, it was filled in a glass bottle, but in recent years, from the viewpoint of weight reduction, reduction of waste, and the like, the number of flexible bag-shaped plastic containers (so-called infusion bag) has been increasing.

[0004] Various chemicals such as amino acid preparations, glucose preparations and fat emulsions filled in infusion bags are easily deteriorated by gas, especially oxygen, but the gas barrier property of the material of the bag is not always sufficient. Therefore, if the infusion bag is left unattended, a gas such as oxygen in the atmosphere passes through the wall of the container and dissolves in the drug solution, which causes the chemical solution to deteriorate over time. Therefore, it has been practiced to coat the infusion bag with a bag having a good gas barrier property.

As described above, the outer bag of this infusion bag is required to have a barrier property against gases such as oxygen. However, in addition to this, it is transparent for visually inspecting the quality of the drug solution as the content. Properties, hand tearability to facilitate bag removal, and pinhole resistance to maintain gas barrier properties during transportation and storage are required.

At present, as an exterior material for an infusion solution,
EVOH film (saponified film of ethylene-vinyl alcohol copolymer), PVA film (polyvinyl alcohol film), polyvinylidene chloride film (PVDC film), PVDC-coated polyethylene terephthalate film (PVD) as a gas barrier layer
A packaging material in which C-coated PET film) and the like are laminated is known. Further, in JP-A-3-142231, the innermost layer is an unstretched polyolefin resin film, the intermediate layer is a biaxially stretched vinylidene chloride / acrylic acid ester-based copolymer film, and the outermost layer is an aluminum oxide-deposited polyethylene terephthalate. However, the intermediate layer and the outermost layer in this packaging material are gas barrier layers.

All of these exterior materials have good gas barrier properties and transparency. However, EVOH, PVA, vapor-deposited PE contained in these exterior materials
Since T and PVDC have high rigidity and little elongation,
If the outer bag bends, rubs, or is subjected to a drop impact due to vibration during transportation of the infusion solution, tissue fatigue is likely to occur. For this reason, pinholes are likely to occur, which may lead to a significant decrease in gas barrier properties.

In addition, crystalline resins such as EVOH and PVA
In the case of PVDC and PVDC, pinholes are more likely to occur because crystallization progresses after melting in the vicinity of the heat-sealed portion, causing an increase in rigidity and a decrease in elongation of that portion.

Particularly, the portion where the pinholes are likely to occur is the bottom portion of the outer bag, and among them, the bent portions (wrinkle portions) on both sides of the bottom portion caused by the bag wall being pushed by the contained infusion bag. At present, infusion bags are packaged in flat bag type outer bags, and some of the outer bags are collectively packaged in a cardboard box for shipment, transportation and storage. In this shipping form, the outer bag is bent, rubbed, or is subject to a drop impact in the cardboard box, but at the same time, the weight of the transfusion agent itself is concentrated on the bottom side of the bag. Therefore, the external force such as bending naturally becomes stronger on the bottom side, and the pinhole is more likely to occur accordingly. In addition, the flat bag type outer bag does not sufficiently follow the shape of the infusion bag to be stored, and the distortion is concentrated on both sides of the bottom of the outer bag to form a significantly bent portion (wrinkle) ( (See FIG. 6). This bent portion is repeatedly bent due to vibration during transportation and the stress of rubbing or drop impact is also concentrated on this portion, so that a pinhole is particularly likely to occur.

[0010]

SUMMARY OF THE INVENTION The present invention has been accomplished in view of the above circumstances, and its object is not only to have good gas barrier properties (particularly oxygen barrier properties) and transparency, but also For example, the present invention relates to a bag body in which pinholes are less likely to be formed due to bending or the like even when a thick article such as an infusion bag is packaged, and a forming material thereof.

[0011]

In order to achieve the above object, the present invention is characterized in that the packaging material contains at least one gas barrier layer composed of an aluminum oxide-deposited nylon film or a silicon oxide-deposited nylon film. And an oxygen-blocking transparent packaging material.

Further, in the present invention, a bag using the above packaging material is provided with an oxygen-blocking transparent packaging material containing at least one gas barrier layer composed of an aluminum oxide vapor-deposited nylon film or a silicon oxide vapor-deposited nylon film. The bag body is characterized in that it is formed and is used for packaging an article having a substantial thickness.

The bag body is preferably constructed such that at least one of the gas barrier layers serves as an intermediate layer. Further, as another preferable aspect, the bag body, having a bottom surface portion of a gusset provided with a flat front surface portion and a rear surface portion facing each other and a valley fold line folded inward in a fold-like shape,
The inner width of the bottom face in the front-rear direction is configured to be equal to or larger than the thickness of the portion of the article located on the bottom face side when stored.

[0014]

The packaging material of the present invention contains at least one gas barrier layer composed of an aluminum oxide-deposited nylon film or a silicon oxide-deposited nylon film as a gas barrier layer. These gas barrier layers have good oxygen barrier properties and transparency. Moreover, since it has higher flexibility and greater elongation than the conventionally used transparent gas barrier layer such as EVOH, pinholes are less likely to occur.

Causes of pinholes include tissue fatigue of the packaging material due to repeated bending, outermost layers of the bag, innermost layers of the bag and stored items, or outermost layers of the bag and inner walls of the outer packaging box. Abrasion of the packaging material due to rubbing between the
Examples include drop impact.

On the other hand, since the packaging material of the present invention is highly flexible, fatigue of the material structure is unlikely to occur even after repeated bending, and pinholes are less likely to occur.
In addition, a bag formed of a highly flexible packaging material has excellent conformability even when a thick article is stored inside, and since it is not stiff, it is difficult for the bent portion to be formed, and the bent portion Even if a ridge is formed, the protrusion is not sharp. Therefore, it is possible to prevent the protruding ridgelines and vertices in the bent portion from being intensively worn, and pinholes are less likely to occur. Furthermore, since the packaging material of the present invention has a large elongation, it is possible to sufficiently absorb a drop impact, and in this respect also pinholes are unlikely to occur.

Another cause of the pinholes is that the packaging material is crystallized in the vicinity of the heat-sealed portion, causing an increase in rigidity and a decrease in elongation in that portion. On the other hand, the gas barrier layer adopted in the present invention has a vapor deposition layer, and since this vapor deposition layer is not a crystalline resin,
Crystallization does not occur near the heat seal part.

As described above, according to the packaging material of the present invention, various causes that cause pinholes can be eliminated at the same time. Therefore, the bag body of the present invention formed by using the packaging material is a thick article. Excellent pinhole resistance even when packaged.

The bag of the present invention is preferably constructed so that at least one of the gas barrier layers serves as an intermediate layer. When the gas barrier layer is used as the intermediate layer, the influence of external stress such as friction or bending on the gas barrier layer is reduced. Since the expansion and contraction of the gas barrier layer due to bending is smaller in the intermediate layer than in the outermost layer, the influence of bending as well as friction is reduced. Furthermore, in the laminating process of the vapor-deposited nylon film, the deterioration of the oxygen barrier property due to rubbing between the vapor-deposited surface and the guide roll becomes a problem, but if the gas barrier layer is an intermediate layer, such rubbing etc. will be minimized. It can be fed out as little as possible. Therefore, pinholes are less likely to occur.

In another preferred embodiment, the bag body of the present invention is
It has a bottom surface of a gusset provided with a front surface portion and a rear surface portion that face each other and a valley fold line that is folded inward in a fold shape, and the inner width of the bottom surface portion in the front-rear direction is the time of storage. The thickness of the article is equal to or greater than the thickness of the portion of the article located on the bottom surface side.

When the bag of the present invention has the above-mentioned structure,
Due to the excellent flexibility of the forming material itself and the gusset of the bottom portion capable of sufficiently absorbing the distortion of the bag generated when a thick article is stored, the shape of the stored article can be followed very well. For this reason, the significantly bent portions that have conventionally occurred on both sides of the bottom of the bag are not formed at all. Therefore, the pinholes that are concentratedly generated in such a significantly bent portion do not occur in the bag body of the above-described preferred embodiment.

[0022]

EXAMPLES Next, examples of the present invention will be shown to explain the present invention more specifically. 1 is a partial cross-sectional view schematically showing the layer structure of an example (101) of the oxygen-blocking transparent packaging material of the present invention. FIG. 2 is a front view of an example (102) of the bag body of the present invention, and FIG. 3 is a perspective view thereof. Further, FIG. 4 is a front view showing a state in which the infusion bag is stored in the bag body (102), and FIG. 5 is an explanatory view showing a state inside thereof. Further, FIG. 6 is a front view showing a packaging state according to an example (201) of a conventional outer layer bag.

The oxygen-blocking transparent packaging material (101) of the present invention shown in FIG. 1 is a stretched nylon film (ON) as the outermost layer 4 and a uniaxial as the first intermediate layer 5 from the outermost layer side toward the innermost layer side. Stretched polypropylene film (uniaxially stretched PP), stretched nylon film (VM-ON) that has undergone aluminum oxide vapor deposition or silicon oxide vapor deposition as gas barrier layer 1 of the second intermediate layer, and linear low density polyethylene film (as innermost layer 6) ( LLDPE) are sequentially laminated, and the layers are adhered to each other via adhesive layers 7-a, 7-b, or 7-c.

In the packaging material of the present invention, one layer or two or more layers of the gas barrier layer 1 composed of an aluminum oxide vapor-deposited nylon film or a silicon oxide vapor-deposited nylon film, preferably an aluminum oxide vapor-deposited nylon film, must be laminated. is there. This gas barrier layer has good oxygen barrier properties and transparency, but it has excellent flexibility and extensibility, and since it does not deteriorate due to crystallization near the heat seal part, it has excellent pin resistance. It also has hall characteristics. Nylon to be vapor-deposited is not particularly limited, but for example, 6-nylon or 6,6-nylon can be used.

The gas barrier layer 1 made of a vapor-deposited nylon film may be the outermost layer, but is preferably an intermediate layer as shown in FIG. When the gas barrier layer 1 is an intermediate layer, the influence of external stress such as friction and bending on the gas barrier layer 1 is reduced, which is advantageous for preventing pinholes. When the gas barrier layer is the intermediate layer, the difference in expansion and contraction of the gas barrier layer due to bending is smaller than when the gas barrier layer is the outermost layer, and therefore the influence of bending is small. Also, atmospheric conditions such as humidity affect the oxygen barrier property of the gas barrier layer, but the intermediate layer has little effect. Furthermore, if the gas barrier layer is an intermediate layer, it is necessary to minimize the deterioration of the oxygen barrier property due to the rubbing of the vapor-deposited nylon film between the guide roll and the vapor-deposited surface during the laminating step for producing the packaging material. You can take it out.

As the laminating material other than the gas barrier layer 1 made of the aluminum oxide vapor-deposited nylon film or the silicon oxide vapor-deposited nylon film, any material can be laminated as long as the object of the present invention is not impaired. In the above packaging material 101, the stretching ON of the outermost layer 4 is laminated to prevent pinholes due to bending and friction and to absorb a drop impact, and the uniaxial stretching PP of the first intermediate layer 5 improves hand tearability. The LLDPE of the innermost layer 6 is laminated for the purpose of ensuring heat sealability at the time of manufacturing and processing into a bag and slipperiness with an article to be packaged and tightly packaging.

The layer thickness of the gas barrier layer 1 is not particularly limited, but from the viewpoint of ensuring sufficient oxygen barrier property and pinhole resistance, the thickness of the nylon film which is the substrate for vapor deposition is usually 12 to 25 μm, preferably The thickness of the vapor-deposited film is usually 12 to 15 μm and is usually 100 to 1000 Å, preferably 200.
~ 600Å The thickness of each layer of the packaging material 101 is
The outermost layer 4, ON, is 12 to 25 μm, the first intermediate layer 5 is uniaxially stretched PP, 10 to 40 μm, the gas barrier layer 1 is VM-ON, and the innermost layer 6 is L.
LDPE is 30 to 80 μm.

To produce the packaging material of the present invention, a nylon film may be vapor-deposited with aluminum oxide or silicon oxide to obtain a vapor-deposited nylon film, and other layers may be laminated with or without an adhesive. . As the vapor deposition method and the laminating method of each layer, conventionally known methods can be appropriately adopted.

The bag body of the present invention formed by using the above-mentioned packaging material has very excellent pinhole resistance, and even if a three-dimensional article having a thickness is packaged, the bag is not distorted. Even if it occurs, the bent portion is hard to be formed. Further, even if a bent portion is formed, it can endure repeated bending well, and furthermore, a sharp apex where the wear of the bag is concentrated is not formed. Therefore, pinholes are unlikely to occur.

In the bag of the present invention, it is preferable that the bottom portion is a gusset having a predetermined width. FIG. 2 is a front view showing a state where the bag body 102 having such a preferable mode is folded, and FIG. 3 is a perspective view showing a state where the bag body 102 is expanded.

The bag body 102 has a flat front surface portion 1 facing each other.
1 and a rear surface portion 12 (not shown) and a bottom portion 13 of a gusset having a valley fold line 14 folded inward in a fold shape, and bonded at a side edge seal portion 17 and a bottom seal portion 16. Is a three-sided sealed bag body. A notch 19 is provided on the top side of the side edge to facilitate opening. Both side edges 18 of the bottom portion 13 are the bag body 10.
As described in 2, it is preferable that the side edge seal portion 17 is integrally heat-sealed in a state of being sandwiched between the front surface portion and the rear surface portion.

4 and 5 show a state in which the infusion bag is stored in the bag body 102 and packaged. In these drawings, the infusion bag is folded in half and stored, and the top of the bag is sealed (15). As shown in FIG. 5, the inner width m of the bottom surface in the front-rear direction needs to be greater than or equal to the thickness n of the portion of the stored article located on the bottom surface side. It is preferable that the inner width m be as close as possible to the thickness n as long as it does not hinder the loading of articles into the bag.
The reason why the inner width m is made close to the thickness n of the article is to more reliably prevent the formation of bending by packaging the article as tightly as possible.

A conventional outer bag for an infusion bag is a flat bag type, and after packaging, as shown in FIG. 6, bent portions are mainly formed on both sides of the bottom portion, which is a significant cause of pinholes. It was On the other hand, the bag body of the present invention having the bottom portion of the gusset closely follows the shape of the infusion bag as shown in FIGS. 4 and 5, and the bent portion is not formed at all, so that the pinhole is not formed. Is extremely rare.

Experimental examples are shown below. 1. Bending test For the following transparent packaging material test pieces, a bending test is performed using a gelbo flex tester (manufactured by Rigaku Kogyo Co., Ltd.),
The number of pinholes appearing when the predetermined number of bends was reached was counted. The test was performed twice for each sample. The test results are shown in Table 1. According to the test results, the number of pinholes appearing in the example was obviously smaller than that in the comparative example.

Example 1 Outermost layer ← [ON (15 μm) / uniaxially stretched PP (17 μm)
m) / aluminum oxide VM-ON (15 μm) / LL
DPE (50 μm)] → innermost layer Example 2; outermost layer ← [aluminum oxide VM-ON (15 μm) /
Uniaxially stretched PP (17 μm) / ON (15 μm) / LLD
PE (50 μm)] → innermost layer Comparative Example 1; outermost layer ← [aluminum oxide VM-PET (12 μm)]
/ PVDC (15 μm) / PE (50 μm)] → innermost layer Comparative Example 2; outermost layer ← [aluminum oxide VM-PET (12 μm)]
/ PVDC (15 μm) / PP (50 μm)] → innermost layer

[0036]

[Table 1] * 1; average of two test values * 2; measured value of each sample 2. Oxygen barrier property test There was no difference in the number of pinholes appearing between Example 1 and Example 2. However, since it was expected that the oxygen barrier layer would deteriorate as a pre-stage of the occurrence of pinholes, an oxygen barrier property test was conducted on both of them. As a test piece,
Each packaging material was used before and after the bending test by the Gelbo flex tester and after the bag was subjected to the drop test. In addition, the test piece of the comparative example was clearly excluded from the subject of the present test because the appearance of more pinholes than that of the example was recognized in the bending test.

As the test piece after the bending test, one that was bent 20 times was used. On the other hand, in order to obtain a test piece after the drop test, the packaging material of each example was heat-sealed to form a flat bag having a height of 320 mm and a width of 300 mm as shown in the middle row of Table 3, and 900 ml thereof was formed. The infusion bag of No. 1 was packaged and packed in a cardboard box, and then dropped from a height of 1.2 m 10 times. Then, the wrinkled portions at the four corners of the outer bag were cut out to obtain test pieces. Second test result
Shown in the table. From the test results, it was confirmed that among the packaging materials of the present invention, the one having the gas barrier layer as the intermediate layer was excellent in the oxygen barrier property even before the test and was less deteriorated after the test.

[0038]

[Table 2] 3. Drop Test A drop test was performed to evaluate the difference in pinhole resistance based on the difference in bag shape. The packaging material of Example 1 was used to produce bags with gusset bottoms, flat bags, and pillow type bags. As shown in Table 3, the dimensions were 320 mm in height and 300 mm in width, and for the gusset bottom, the height of the valley fold line from the bottom was 46 mm. A 900 ml infusion bag is packed in these bags, packed in a cardboard box, and then dropped from a height of 1.2 m, and pinholes are dropped at each of 10, 20, 30, and 40 times. The number of appearances of was counted. The test was performed twice for each bag of the same type.

The test results are shown in Table 4. In the flat bag and pillow bag, pinholes began to appear after dropping 30 times, but three pinholes appeared after dropping 40 times, but for gusset bottom, pinholes appeared even after dropping 40 times. Was not recognized.

[0040]

[Table 3]

[0041]

[Table 4] * 1; Average of two test values * 2: Measured value of each sample

[0042]

As described above, the oxygen-shielding transparent packaging material of the present invention has good transparency and oxygen barrier properties, as well as excellent pinhole resistance. Therefore,
It can be used as a bag for packaging thick articles in various fields including medical articles and foods. In particular, it can be suitably used as a bag for medical use, which is highly demanding for transparency and gas barrier properties.

The bag of the present invention provided with a gusset having a predetermined width on the bottom surface is suitable for packaging thick articles, particularly flat or generally flat shape articles. It can be used as an outer bag of a bag.

[Brief description of drawings]

FIG. 1 shows an example of an oxygen-blocking transparent packaging material of the present invention (10
It is a fragmentary sectional view which shows typically the layer constitution of 1).

FIG. 2 is a front view of an example (102) of the bag body of the present invention.

3 is a perspective view of the bag body (102) of FIG. 2. FIG.

FIG. 4 is a front view showing a state where an infusion bag is stored in the bag body (102) of FIG.

5 is an explanatory view showing a state inside the packaging body of FIG. 4. FIG.

FIG. 6 is a front view showing a packaging state of an example (201) of a conventional outer bag.

[Explanation of symbols]

 101 ... Oxygen-blocking transparent packaging material of the present invention 102 ... Bag of the present invention 201 ... Conventional outer bag 1 ... Gas barrier layer 2 ... Deposition film 3 ... Nylon film 4 ... Outermost layer 5 ... Intermediate layer 6 ... Innermost layer 7 ( 7-a, 7-b, 7-c) ... Adhesive layer 11 ... Front part 12 ... Rear part 13 ... Bottom part 14 ... Valley fold line 15 ... Top seal part 16 ... Bottom seal part 17 ... Side edge seal part 18 ... Side edge of bottom part 19 ... Notch 20 ... Opening part 21 ... Infusion bag 22 ... Bending part (wrinkle) 23 ... Apex of bending m ... Inner width of bottom part n ... Thickness of infusion bag on bottom part side

Continuation of front page (51) Int.Cl. ⁶ Identification code Office reference number FI technical display location C23C 14/20 A61J 1/00 390S

Claims (4)

[Claims] 1. An oxygen-blocking transparent packaging material comprising at least one gas barrier layer made of an aluminum oxide vapor-deposited nylon film or a silicon oxide vapor-deposited nylon film. 2. For packaging an article having a substantial thickness, which is formed by an oxygen-blocking transparent packaging material containing at least one gas barrier layer comprising an aluminum oxide vapor-deposited nylon film or a silicon oxide vapor-deposited nylon film. A bag body characterized by being used for. 3. At least one of the gas barrier layers comprises:
The bag according to claim 2, which is an intermediate layer. 4. A gusset bottom surface portion having a front surface portion and a rear surface portion facing each other and a valley fold line folded inward in a fold shape, and an inner dimension width of the bottom surface portion in a front-rear direction. 3. The bag according to claim 2, wherein the thickness is equal to or greater than the thickness of the portion of the article located on the bottom surface side when the article is stored.