JPH08278311A - Automatic analysis device for analyzing samples such as blood and urine - Google Patents

Abstract

PURPOSE: To provide a compact automatic analysis device which can cope with more inspection items as compared with an automatic analysis device at an equal scale and can be easily handled. CONSTITUTION: An automatic analysis device is provided with a sample table 2 where a number of samples are arranged, a reagent table 9 a number of specific reagents used only for a specific inspection and a common reagent commonly used for a plurality of inspections are arranged, and a reaction table 5 for enabling the sample to react with the regent by mixing them. Also, it is provided with a first carrier arm for carrying the sample from the sample table 2 to the reaction table 5, a second carrier arm for carrying the reagent from the reagent table 9 to the reaction table 5, and a control device for controlling each table and each arm in synchronization and allowing at least one type of reagent to react with the sample on the reaction table 5.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a simple automatic analyzer for analyzing a sample such as blood or urine in an emergency,
In particular, the present invention relates to a discrete type automatic analyzer for reacting a plurality of kinds of analysis items on the same reaction line.

[0002]

2. Description of the Related Art An example of a discrete type automatic analyzer for reacting a plurality of types of analytical items on the same reaction line is disclosed in U.S. Pat. No. 4,451,433. Further, as a simple type automatic analyzer, there is one described in JP-A-58-2114857.

In all of these analyzers, a sample table on which a large number of samples are arranged, a reagent table on which reagents are arranged, a reaction table for mixing the samples and the reagents to cause a reaction, and the sample A transfer arm for transferring a sample from the table to the reaction table, a transfer arm for transferring a reagent from the reagent table to the reaction table, and the tables and the arms are controlled in synchronization with each other. It is composed of a control device for reacting the sample and the reagent on the reaction table.

[0004]

The problem to be solved by the invention will be described with reference to FIG. In each of the above-described automatic analyzers, the reagent is arranged on the reagent table for each inspection item. That is, for example, for the inspection item 1, the specific reagent A-R
In the case of using 1, A-R2 and common reagent a and specific reagent B-R1, B-R2 and common reagent a for test item 2, as shown in FIG. 3 (A). In addition, the conventional device requires two common reagents. For this reason,
As the number of inspection items increases, the number of reagent bottles that is close to the number of inspection items is required, and it is inevitable that the reagent table becomes large and the analysis apparatus as a whole becomes large.

The object of the present invention is to be able to urgently deal with a larger number of inspection items as compared with an automatic analyzer of the same scale.
Another object is to provide a small automatic analyzer that is easy to handle.

[0006]

In order to achieve the above object, the present invention is configured as follows.

In the automatic analyzer according to the first aspect of the present invention, a sample table on which a large number of the above-mentioned samples are arranged, a large number of specific reagents used only for a specific test and a plurality of tests are commonly used. A reagent table in which a common reagent is arranged, a reaction table for mixing the sample and the reagent to cause a reaction, a first transfer arm for transferring the sample from the sample table to the reaction table, and the reagent table Second for transporting reagents from the above to the reaction table
A transfer arm, a control device that controls the tables and the arms while synchronizing with each other, and causes the sample to react with at least one type of reagent on the reaction table are provided. When the automatic analyzer is used, reagents A, B, which are commonly used for a plurality of test items,
With regard to, all common reagents, one for each, are mixed with a large number of specific reagents and arranged on the reagent table. More specifically, the memory in the control device includes
One reagent and its arrangement position are stored only in a one-to-one relationship, and in the control device, the second transfer arm is previously determined in a one-to-one relationship with respect to one reagent, and the above-mentioned arrangement is performed only from the arrangement position. The second transfer arm is controlled so that one reagent is taken out.

Also, in the automatic analyzer according to the second aspect of the present invention, the sample table, the reagent table, the reaction table, the first transfer arm, and the second transfer arm. −
The printer, the printer, and the display device are installed in a very narrow area of 0.56 square meters or less, concentrated on the top of the main body of the automatic analyzer.

Further, in the automatic analyzer according to the third aspect of the present invention, the display surface of the display device is arranged at the position closest to the access position of the operator together with the power source of the main body of the automatic analyzer. There is.

[0010]

In the automatic analyzer according to the first aspect of the present invention,
In the memory in the control device, one reagent and its arrangement position are stored only in a one-to-one relationship, the control device,
The second transfer arm is previously defined in a one-to-one relationship with one reagent and is configured to take out the one reagent only from the arrangement position. Therefore, for the reagents A, B, ... Commonly used for a plurality of inspection items, only one common reagent may be mixed with a large number of specific reagents and arranged on the reagent table. . That is, even when the common reagent a is used for many test items 1, 2, etc., only one common reagent a needs to be arranged in the reagent table. Therefore, even if the reagent table is small, more reagents can be arranged and more test items can be accommodated.

Further, in the automatic analyzer according to the second aspect of the present invention, in addition to the above configuration, a printer and a display device for outputting the above reaction results are provided integrally with the main body of the automatic analyzer. In that device, the sample table
Table, the reagent table, the reaction table, the first
The transfer arm, the second transfer arm, the printer, and the display device are installed on the top of the automatic analyzer.
It is located in an extremely narrow area of 56 square meters or less. The reason why it can be arranged in such a narrow area is that the installation space of the reagent table can be minimized by adopting the above-mentioned configuration.
This is because the arm length of the transfer arm can be reduced.

Further, in the automatic analyzer according to the third aspect of the present invention, the display surface of the display device is arranged at the position closest to the access position of the operator together with the power source of the main body of the automatic analyzer. There is. Therefore, not only is the display surface extremely easy to see, but it is also easy to check whether the power supply is on or off.

[0013]

1 is a schematic configuration diagram of an embodiment of an automatic analyzer according to the present invention, and FIG. 2 is an external view of the device shown in FIG.

In FIGS. 1 and 2, 1 is a sample container containing a sample to be analyzed, 2 is a sample disk on which the sample container 1 is placed, 3 is a sample identification of a bar code label attached to the sample container 1. It is a bar code reader for reading the bar code 4 for use.

The sample in the sample container 1 is the reaction disk 5
It is dispensed into the reaction container 6 of. This dispensing is performed by the sample dispensing device 7. Reference numeral 8 is a reagent container containing a reagent to be reacted with the sample, 9 is a reagent disk holding the reagent container 8, and 10 is a content of a reagent identifying bar code 11 of a bar code label attached to the reagent container 8. Is a bar code reader for reading. Reference numeral 12 is a reagent dispensing device that dispenses the reagent in the reagent container 8 into the reaction container.

Reference numeral 13 is a sample syringe for sucking the sample in the sample container 1 into the sample dispensing device 7 and discharging it into the reaction container 6, and 14 is sucking the reagent into the reagent dispensing device 12 and discharging it into the reaction container 6. A reagent syringe 15 for performing the operation is an agitating device for agitating the sample and the reagent contained in the reaction container 6. Reference numeral 16 is a photometer for measuring the change in absorbance of the sample that has reacted with the reagent, 17 is a light source, 18 is a constant temperature bath for keeping the reaction container 6 at a constant temperature, 19 is a washing device for washing the reaction container 6 after analysis, and 20 is washing. This is a cleaning water supply device that supplies water to the device 19 and sucks waste liquid.

Reference numeral 21 is a computer for performing control processing and measurement signal processing. The computer 21 has a CPU.
Logarithmic amplifier (LOG amplifier) and AD via bus 22
A converter 23, a memory 24, a floppy disk drive 25, a printer 26, a keyboard 27 and a display device 28 are connected. This display device 2
The reference numeral 8 is attached to the top of the main body of the automatic analyzer and at a position close to the position accessed by the operator. Also,
A power switch 40 of the apparatus main body is provided near it.

Reference numeral 29 is an external computer which has data relating to samples and reagents and which provides the data to the automatic analyzer. The identification code of the reagent and the sample obtained by the automatic analyzer is sent to the external computer 29,
Further, a communication device 30 and a communication line 31 for receiving data from an external computer and sending it to the automatic analyzer and a communication device 32 of the external computer are added.

In addition, in FIG. 2, in order to improve the handling of the reagent, the display device may be further elongated and the sample table may be installed on the front side (access direction). Also in this case, it is preferable that the depth is about 700 mm and the maximum width is 800 mm in view of installation space and operability.

Referring to FIG. FIG. 3A shows an example of arrangement of conventional reagent bottles. In addition, FIG.
3 shows an example of arrangement of reagent bottles in the automatic analyzer of the present invention. In the figure, 8 is a reagent bottle and 9 is a reagent disc. As is apparent from FIG. 3, in the past,
For example, the reagent a is the inspection item 1 (used reagents A-R1, A-R).
2, a) and inspection item 2 (reagents B-R1, B-R used)
When both 2 and a) are used, it is necessary to prepare reagent bottles of the number of reagent bottles (here, 2) corresponding to the number of items used. Therefore, when the number of inspection items is large, the number of required reagent bottles is increased, and as a result, it is necessary to reduce the number of inspection items or increase the size of the reagent disc. On the other hand, in the present invention, for reagents commonly used for a plurality of test items,
Only one common reagent may be mixed with a large number of specific reagents and placed on the reagent table. That is, even when the common reagent a is used for many test items 1, 2, etc., only one common reagent a needs to be arranged in the reagent table. Therefore, the size of the reagent disk can be made smaller than the conventional one with respect to the generally desired number of inspection items.

Next, the operation of the automatic analyzer according to the present invention using such a small reagent disk will be described.

First, referring again to FIG. 1, the overall analysis operation will be briefly described. In normal analysis, the sample is placed in the sample container 1 and the sample disc 2
Set on. Then, the sample in the sample container 1 is sucked and discharged into the reaction container 6 by the sample pipetting mechanism and the sample dispensing mechanism. next,
Necessary reagents are taken out from the reagent container 8 on the reagent disk 9 by the reagent pipetting mechanism and the reagent dispensing mechanism and dispensed into the reaction container 6. Then, the sample and the reagent in the reaction container 6 are stirred and reacted by the stirring mechanism.

The sample reacted in the reaction vessel 6 is measured by a photometer, amplified by a LOG amplifier, then digitized by an A / D converter 23, and converted into C
It is taken into the memory 24 via the PU bus 22. All of these operations are controlled by the control CPU 21,
The results of the analysis are processed and the floppy disk 2
5 is displayed on the display device 28 and printed on the printer 26 at the same time.

Next, the reagent dispensing operation will be described with reference to FIG. FIG. 4 is a flow chart showing the reagent dispensing operation in the automatic analyzer according to the present invention. In step S1, the apparatus is turned on and preparations for reagent dispensing are made. Next, in step S2, the inspection item name,
The types of reagents R1, R2, ... Used and the set positions of the reagent bottles are set. That is, step S
In 2, the inspection item, the reagent type used for it, and the set position of the reagent bottle are stored in the memory of the control device in a one-to-one relationship. After that, the start of reagent dispensing is determined (step S3). If the preparation for starting the reagent dispensing is completed, the inspection item to be analyzed is first inquired and specified by the CPU in step S4. If the preparation for starting the reagent dispensing is not completed, the process returns to step S2. When the inspection item is specified in step S4, the type of reagent used for the next inspection is inquired to the CPU and specified (step S5). Subsequently, based on the information obtained in the previous steps S4 and S5, the bottle position of the reagent to be dispensed is determined in step S6, the reagent pipette is moved to a predetermined position in step S7, and the reagent bottle is removed from the reagent bottle. Aspirate the reagent and transport it to the reaction disc. The reagent is dispensed in step S8, and the reagent dispensing operation ends (step S9).

[0025]

According to the present invention, since the reagent disk and the like can be downsized, more test items can be handled and the handling is easier, as compared with the automatic analyzer of the same scale. A small automatic analyzer is provided.

[Brief description of drawings]

FIG. 1 is an overall schematic configuration diagram of an embodiment of the present invention.

FIG. 2 is an external view of an embodiment of the present invention.

FIG. 3 is a schematic diagram showing a comparative example of arrangement of reagent bottles in the related art and the present invention.

FIG. 4 is a schematic flowchart showing a reagent dispensing operation in the present invention.

[Explanation of symbols]

 2 sample disk 5 reaction disk 9 reagent disk 12 reagent pipetting 24 memory 26 printer 28 CRT 100 automatic analyzer body

Claims (5)

[Claims] 1. An automatic analyzer for analyzing a sample such as blood or urine, comprising a sample table on which a large number of the above samples are arranged, a large number of specific reagents used only for a specific test, and a plurality of tests. A reagent table on which a common reagent commonly used is arranged, a reaction table for mixing the sample and the reagent to cause a reaction, and a first transfer arm for transferring the sample from the sample table to the reaction table. A second transfer arm for transferring the reagent from the reagent table to the reaction table, the tables and the arms are controlled in synchronization with each other, and at least one kind of the sample and the sample on the reaction table are controlled. In an automatic analyzer having a controller for reacting a reagent, the memory in the controller stores only one reagent and its arrangement position in a one-to-one relationship. The control device controls the second transport arm so that the second transport arm is predetermined in a one-to-one relationship with one reagent and the one reagent is taken out only from the arrangement position. An automatic analyzer characterized by: 2. The automatic analyzer according to claim 1, further comprising a printer and a display device for outputting the reaction result, the sample table, the reagent table, the reaction table, and the reaction table. First transport arm, second above
An automatic analyzer, wherein the transport arm, the printer and the display device are installed in an area of 0.56 square meters or less on the top of the automatic analyzer. 3. The automatic analyzer according to claim 2, wherein the display surface of the display device is arranged at a position closest to the access position of the operator together with the power source of the main body of the automatic analyzer. Automatic analyzer. 4. An automatic analyzer for analyzing a sample such as blood or urine, comprising a sample table on which a large number of the samples are arranged, a large number of specific reagents used only for a specific test and a plurality of tests. A reagent table in which common reagents commonly used are mixedly arranged, a reaction table for mixing the sample and the reagent to perform a reaction, and a first for transporting the sample from the sample table to the reaction table The transfer arm, the second transfer arm for transferring a reagent from the reagent table to the reaction table, the tables and the arms are controlled in synchronization with each other, and at least one type of sample and at least one type of sample is displayed on the reaction table. An automatic analyzer equipped with a controller for reacting a reagent. 5. The automatic analyzer according to claim 4, further comprising a display device for displaying the reaction result, the display device being integrated with the main body of the automatic analyzer, and the display device. An automatic analyzer characterized in that the display surface of the device is arranged at the position closest to the access position of the operator together with the power source of the main body of the automatic analyzer.