JPH08206229A - Medicine dosing device - Google Patents

Abstract

PURPOSE: To make it possible to correctly dose medicines to a lesion by preventing the occurrence of clogging in a tube with an inexpensive and simple structure. CONSTITUTION: The inside of a guide tube 10 is nearly hermetically closed by the effect of a leaf spring 13 to prevent the occurrence of clogging in the tube 4 for dosing the internal medicines at the time of not-dosing the medicines. The tube 4 is extruded to expose its front end outside and the medicines are injected together with a compressed gas toward the lesion when the stage for dosing the medicines is attained.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a drug administration device, and more particularly to a drug administration device which administers a drug by the action of compressed gas.

[0002]

2. Description of the Related Art The applicant of the present application has proposed a technique in which a drug is inserted into a forceps port provided in an endoscope and a drug is administered to an affected area by the action of compressed gas compression (Japanese Patent No. 1735127).
issue).

According to the proposal, particularly in the case of a powdered medicine, for example, it is possible to spray the affected area evenly and evenly, so that a very excellent effect as a therapeutic method can be achieved.

[0004]

Generally, when a subject to be administered is a hollow organ such as stomach, the empty channel (forceps port) of the endoscope is thrown to send air into the stomach to expand the stomach. After that, the stomach wall is observed or diagnosed. And when using the device disclosed in the above patent,
First, this operation is required.

In any case, since the stomach is filled with air (or carbon dioxide gas) in order to facilitate observation with an endoscope, the air pressure inside the stomach is naturally high. Therefore, when the device of the above patent is used, the liquid in the stomach (such as secretory liquid or water for cleaning the lens of the endoscope) may easily flow back from the tip of the drug administration tube. become.

However, if the liquid enters the inside of the tube, it is naturally difficult to properly administer the drug. In particular, the smaller the particle size of the drug such as powder, the higher the incidence of this problem.

Further, even in the process of inserting the endoscope through the mouth of the patient, the tip of the endoscope may get wet. Even if the tube of the above patent is then inserted through the forceps mouth, this problem occurs. There is no denying the possibility of doing so.

[0008]

[Means for Solving the Problems] and

The present invention has been made in view of the above problems, and it is possible to prevent clogging in a tube with an inexpensive and simple structure and to administer a drug to the affected area correctly. It is intended to provide a drug administration device.

In order to solve this problem, the drug administration device of the present invention has the following configuration. That is, a tube for passing a medicine, a compressed gas generating means for generating a compressed gas, a holding means for holding a medicine to be administered between the tube and the compressed gas generating means, and the compressed gas generating means. And a supply means for supplying the gas generated in 1. to the holding means, and the medicine is administered by releasing the medicine from the tip of the tube by the action of the compressed gas supplied by the supply means. And
A second tube that allows sliding of the tube is provided outside the tube, and a lid portion that seals the tip portion of the second tube with a predetermined pressure is provided at a tip position of the second tube. Is characterized by.

According to a preferred embodiment of the present invention, a direction in which the second tube is hermetically closed at the end of the second tube at the lid portion with a predetermined pressure. It is desirable to have a spring acting on. As a result, the sealed state can be maintained at any time except when the drug is administered.

According to another preferred embodiment, the lid portion is a detachable cover for covering the distal end portion of the second tube with a predetermined pressure, and is made of a harmless material that is at least dissolved in the human body. It is desirable to be done. This allows the structure to be extremely simple and inexpensive.

According to another preferred embodiment, it further comprises a second supply means for supplying the compressed gas generated by the compressed gas generating means directly to the tube, bypassing the holding means. Is desirable. As a result, even if liquid enters the tube, that portion can be blown off, so that even if there is clogging, it can be removed.

According to a preferred embodiment, the second
The outer shape of the tube is preferably at least equal to or smaller than the diameter of the forceps port provided in the endoscope. With this structure, it becomes possible to directly administer the drug to the stomach or the like through the endoscope.

[0014]

Embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

FIG. 2 shows the appearance of the endoscope 20 to which the embodiment is applied. In the figure, reference numeral 21 denotes a distal end portion of the flexible tube 27 through which the affected area is observed and various treatment groups are put in and taken out. Reference numeral 22 denotes an eyepiece, from which the vicinity of the tip 21 is observed. 23 is the tip 2
Angle knob for controlling the bending direction in the vicinity of 1, 25
Is a cable for connecting to a light source, a suction / intake pump, and various processing devices. Inside the tube 27, an optical path for guiding the image from the distal end portion 21 to the eyepiece 22 (often composed of a bundle of glass fibers), a path for inhaling air, and a light for the affected area. The optical path for irradiating the laser beam is provided, as well as a path for passing various forceps inserted from the forceps port 26 shown in the figure.

The drug administration device in the embodiment utilizes this forceps port 26. The endoscope shown in FIG. 2 is a general one, not a special one.

FIG. 1 is a structural cross section of the main body of the drug administration device according to the embodiment.

In the figure, 1 is a forceps device, 2 is a compressed gas chamber, 3 is a drug chamber for holding a drug to be administered, and 4 is a tube for guiding the drug to an affected area. Reference numeral 10 is a guide tube for guiding the tube 4, the details of which will be described later. The tube 4 and the guide tube 10
Has a length such that its tip is exposed from the tip 21 of the endoscope 20 at least when it is inserted into the forceps port 26 of the endoscope 1. A cartridge 8 containing a drug (pills in this case) 9 can be stored in the medicine chamber 3.

Reference numeral 6 denotes a valve for preventing the compressed gas from being filled into the compressed gas chamber 2 and preventing the compressed gas from leaking, and is normally positioned at the solid line position by the action of a spring (not shown). When the high-pressure gas is supplied from the outside, the compressed gas is retracted to the position shown by the broken line, whereby a predetermined amount of the compressed gas can be stored in the compressed gas chamber 2. 7
Is a switch for controlling opening / closing of the passage between the compressed gas chamber 2 and the medicine chamber 3. This switch 7
Is normally in the position shown in the figure by the action of the compression spring 7c, and the ventilation passage 7a maintains the compressed gas chamber 2 and the drug chamber 3 in a blocked state. The switch 7 has an O-ring 7b.
Etc. are provided so that the compressed gas does not leak to the outside.

Now, in the structure shown in the figure, when the switch 7 is pushed in now, the compressed gas chamber 2 and the chemical chamber 3 are connected to the ventilation passage 7a.
The connection is established via. As a result, the compressed gas in the compressed gas chamber 2 is released toward the drug chamber 3. When the compressed gas is released into the medicine chamber 3, the pills 9 settled in the cartridge 8 are pushed out toward the tube 4 by the compressed gas (or released together with the compressed gas).

Therefore, under such a circumstance, if the tube 4 and the guide tube 10 are inserted into the forceps port 26 provided in the endoscope 20, it is possible to discharge the pill from the tip portion 21 thereof. become. Also, with pills,
Above all, it was confirmed that the one having a low hardness was broken into small pieces while passing through the tube. As a result, it is appropriately spread over the affected area (the extent of the spread depends on the tip of the endoscope 2
1 can be changed depending on the distance between the affected area) and the drug can be uniformly administered.

Particularly, a good drug is not a pill as shown in FIG. 1 but a powdered drug. At this time,
The drug could be administered only to the affected area and evenly.

Incidentally, although the description will be mixed up, it is needless to say that the compressed gas used in the examples is carbon dioxide or the like which does not adversely affect the human body.

Now, the reason why the guide tube 10 is provided outside the tube through which the medicine passes in the above structure will be described.

FIG. 3 shows a cross section of the forceps device 1 of the embodiment in the vicinity of the distal ends of the tube 4 and the guide tube 10.

FIG. 3A shows a normal state (when no drug is administered). As shown in the figure, a lid 12 is provided at the tip of the guide tube to prevent backflow of foreign matter (such as gastric juice) into the guide tube 10. The lid 12 and the guide tube 10 are provided with a leaf spring 13 By the action of, the closed state is maintained as illustrated.

Returning to FIG. 1, when the knob 11 provided at the end of the guide tube 10 is pulled or the device 1 is pushed out with respect to the knob 11, the tube 4 moves inside the guide 10. As a result of sliding, the tip of the tube 4 pushes out the lid 12 shown in FIG. 2 (A). FIG. 2B shows a state in which this extrusion is completed. It should be noted that the tube 4 needs to slide smoothly with respect to the guide tube 10, although the description will be mixed up. Therefore, the inner surface of the guide tube and the outer surface of the tube 4 are used after being subjected to the corresponding processing. Since such processing technology itself is known,
The description is omitted.

Here, as described above, since the drug and the gas pass by the gas compression, the tip of the tube 4 has a relatively relatively large portion so that the drug can be surely released. The discharge part 14 made of a hard material is provided. As a result, a certain amount of opening is ensured at the drug administration port by the discharge part 14, and good drug administration can be performed. If the tube 4 itself has a certain degree of hardness, the emission portion may be formed by extending it.
Therefore, it is not always necessary to provide the discharge part 14 made of a different material as shown.

By using the forceps device 1 of the embodiment having the above structure, the following effects can be obtained.

That is, the process of inserting the endoscope 20 through the patient's mouth or the like, and the distal end portion 2 of the affected part (stomach, etc.).
When 1 arrives, even if the tip is wet with secretion liquid or washing water (water discharged from the mechanism for washing the tip of the endoscope), the guide tube 10 and the lid 12 keep the medicine in It is possible to prevent the tube 4 for guiding the liquid from getting wet.

Therefore, even when the powdered drug is administered by the action of the compressed gas, it is solidified in the tube 4 (mostly in the vicinity of the tip end) thereof, which adversely affects the injection of the drug. It becomes possible not to give.

In the above embodiment, the guide tube 10 is used.
The lid 12 is connected to the tip of the plate by the leaf spring 13, but the present invention is not limited to this.

FIG. 4 is a view showing an example in which the lid 12 'and the guide tube are integrated. As shown in the figure, this structure is sufficient as long as it is possible to maintain a hermetically sealed state to some extent, and it is advantageous in terms of cost as compared with the above example.

In the above embodiment, the cartridge 8 containing the medicine has been described as being contained in the medicine chamber 3. However, in this case, the loading operation of the next medicine cartridge is performed every time the medicine is administered once. It must be made.

FIG. 5 shows the structure of a forceps device capable of continuously administering a drug. In the figure, reference numeral 40 is a chamber for accommodating a medicine, which is connected to the medicine chamber 3 via a valve 41. With this configuration, each time the medicine is administered, the medicine in the chamber 40 is filled in the medicine chamber 3 so that treatment can be performed many times. In addition, in FIG. 5, the example which used the powdery chemical | medical agent was shown.

<Description of Second Embodiment> In the above embodiment,
An example in which the guide tube 10 and the tube through which the medicine actually passes has a double structure and a lid is provided at the tip of the guide tube has been shown. The lid is provided on the tube 4 for spraying the medicine.
However, the present invention does not limit the present invention by the fact that it does not get wet (or does not get wet) when the drug is administered. For example, a cover made of the same material as the packaging material for the commonly used capsules for internal use may be attached to the tip of the guide tube 10.

FIG. 6 shows a tube 4 according to the second embodiment.
3 is a structural diagram of the vicinity of the tip of the guide tube 10. FIG.
The forceps device itself has the structure of FIG. 1 or 5 described in the above embodiment.

In the figure, 15 is a cover of the same quality as the capsule of the oral capsule. However, the outer diameter of the guide tube of the starting device assumed in the embodiment is at most a few millimeters, and it is necessary to make it suitable for it.

When the drug is injected (sprayed), the tube 4 is pushed out to drop the cover 15 as shown in the figure, and then the drug is sprayed. However, once the cover is dropped, it cannot be reattached during treatment. In this respect, it can be said that the first embodiment is superior.

As a matter of course, the cover 15
Is harmless to the human body and does not adversely affect the human body.

<Explanation of Third Embodiment> In the first and second embodiments described above, it is intended to prevent the tip of the tube from getting wet. On the contrary, when it gets wet, the liquid portion of the tube is used as an embodiment. It may be removed by the action of the compressed gas. This example will be described as a third embodiment.

FIG. 7 shows a schematic circuit diagram of the forceps device according to the third embodiment as viewed from above. Further, FIG. 8 shows a sectional view taken along line AA in FIG. 7.

The difference from the structure of FIG. 1 or 5 described above is that a bypass air passage 70 is newly provided.
The point is that a switch 71 is provided for controlling connection / disconnection between the tube 4 and the air passage 70 and connection / disconnection between the tube 4 and the drug chamber.

The switch 7 is assumed to be the same as that shown in FIG. 1 or 5, and only the switch 71 will be described here.

The switch 71 is normally in the position shown by the action of the compression spring 71c. That is, the ventilation path 7
a is in a state of connecting the medicine chamber 3 and the tube 4.
Therefore, when the switch 7 is pushed down in this state, the drug can be administered to the affected area as described in the above embodiment.

When the switch 71 is pushed down, the medicine chamber 3 and the tube 4 are shut off from each other. When it is further pushed down, the air passage 71d bypasses the air passage 70 and the tube 4.
The state of connecting and. Here, the air passage 71d and the tube 4 on the right side in the figure have an L-shape extending in the front direction of the drawing.

With the above configuration, for example, when the compressed gas is stored in the compressed gas chamber 2 and the switch 71 is depressed,
Compressed gas only (I explained that the chamber 3 is shut off)
Will flow out into the tube 4. Therefore, even if liquid enters the tip of the tube 4, the liquid portion can be blown off.

In the experiment, it was confirmed that most of the liquid can be removed by using the above structure.

However, a greater effect can be obtained by using the structure of the third embodiment and the mechanism of the first or second embodiment in combination.

That is, although the structure of the third embodiment is also useful, in order to administer the drug more efficiently, it is desirable to use it in combination with the first or second embodiment.

It is needless to say that the combined use method is simply required to provide the guide tube as shown in FIG. 1 on the outer side of the tube 4 in FIG.

As described above, according to the embodiment, in the forceps device for injecting (injecting) the drug through the tube by the action of the compressed gas, the tip of the tube gets wet with the liquid (body fluid or the like). Since it can be prevented, even a powdered drug does not cause clogging, and the drug can be well administered to the affected area.

In particular, by using the apparatus structure described in the third embodiment and the structure described in the first or second embodiment in combination, the above effect can be further improved. .

In the embodiment, the example in which the drug is administered to the affected area via the endoscope has been described, but it may be unnecessary for an extremely shallow portion, for example, a portion in the mouth where direct observation is possible. In this case, the tube 4 and the guide tube 10 do not need to be so long, and it is easy to reflect the action of the compressed gas even on the tip of the tube.
It is possible to obtain a sufficient effect with only one of the embodiments described above. Therefore, the present invention is not limited to the device used for the endoscope.

However, when the internal compression of the stomach or the like is increased (expanded) and the treatment is performed while observing the inside,
Naturally, it would be a prerequisite to use an endoscope.

Further, in the above embodiment, the compressed gas chamber 2 was filled from the outside (for example, the compressor), and then the switch 7 was operated to administer the drug. However, it goes without saying that a portion for generating the compressed gas may be provided in the present apparatus, and the generation source thereof may be located anywhere. However, since a mechanism that expels air inadvertently cannot obtain a very high gas compression, it is advantageous to once store the gas in the compression chamber 2 as in the above embodiment.

[0057]

As described above, according to the present invention, when a drug is administered to an affected area through a flexible tube by the action of compressed gas, the tube has a simple structure and a low cost. It is possible to prevent clogging and reliably administer the drug.

[Brief description of drawings]

FIG. 1 is a structural cross section of a main body portion of a drug administration device according to an embodiment.

FIG. 2 is a diagram showing an external appearance of an endoscope to which an embodiment is applied.

FIG. 3 is a diagram showing a cross section of a forceps device tube and a guide tube in the vicinity of the tip end portion of the embodiment.

FIG. 4 is a view showing an example in which a lid and a guide tube are integrated.

FIG. 5 is a diagram showing a structure of a forceps device that can continuously administer a drug.

FIG. 6 is a structural diagram in the vicinity of tips of a tube and a guide tube in a second embodiment.

FIG. 7 is a schematic diagram of a circuit when viewed from above the forceps device in the third embodiment.

8 is a diagram showing a cross-sectional view taken along the line AA in FIG.

[Explanation of symbols]

 1 forceps device 2 compressed gas chamber 3 drug chamber 4 tube 6 valve 7 switch 8 cartridge 9 drug 10 guide tube

Claims (5)

[Claims] 1. A tube for passing a medicine, a compressed gas generating means for generating a compressed gas, and a tube between the tube and the compressed gas generating means,
A holding means for holding the drug to be administered, and a supply means for supplying the gas generated by the compressed gas generating means to the holding means, and the tip of the tube by the action of the compressed gas supplied by the supply means. A drug administration device which administers a drug by releasing the drug from a second tube, the second tube allowing the slide of the tube outside the tube, and a predetermined pressure at a tip position of the second tube. Therefore, a drug administration device comprising: a lid portion that seals the distal end portion of the second tube. 2. The lid portion is provided with a spring that is openable and closable at the tip of the second tube and that acts in a direction to seal the second tube with a predetermined pressure. The drug administration device according to item 1. 3. The lid is a detachable cover that covers the distal end of the second tube with a predetermined pressure, and is made of a harmless material that at least dissolves in the human body. The drug administration device according to item 1. 4. The second supply means for directly supplying the compressed gas generated by the compressed gas generating means to the tube by bypassing the holding means. The drug administration device according to the item. 5. The drug administration device according to claim 1, wherein the outer shape of the second tube is at least equal to or smaller than the diameter of the forceps port provided in the endoscope.