JPH08175971A - Pasty wafer - Google Patents
Pasty waferInfo
- Publication number
- JPH08175971A JPH08175971A JP34084794A JP34084794A JPH08175971A JP H08175971 A JPH08175971 A JP H08175971A JP 34084794 A JP34084794 A JP 34084794A JP 34084794 A JP34084794 A JP 34084794A JP H08175971 A JPH08175971 A JP H08175971A
- Authority
- JP
- Japan
- Prior art keywords
- medicine
- wafer
- pasty
- taste
- facilitate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
Description
【0001】[0001]
【産業上の利用分野】 内用薬、特に散剤はその味や物
性などにより服用しにくいことがある。また、高齢者や
乳幼児においては散剤のみならず、錠剤やシロップ剤で
さえも服用拒否を示すことがある。本発明は内用薬を服
用し易く変えるための添加剤である。[Industrial field] Internal medicines, especially powders, may be difficult to take due to their taste and physical properties. In addition, not only powders but also tablets and syrups may be rejected in the elderly and infants. The present invention is an additive for changing the internal medicine to be easy to take.
【0002】[0002]
【従来の技術】 紙状オブラートで包むか、清涼飲料水
などに混合して服用。[Background Art] Wrapped in a paper-like wafer or mixed with soft drinks and taken.
【0003】[0003]
【発明が解決しようとする課題】 従来の技術ではオブ
ラートが破れたり口腔内に張り付いて飲み下せない、清
涼飲料水に混合したところ容量が多くなり過ぎたり味が
まずくなって飲み残した、などの課題があった。[Problems to be Solved by the Invention] In the prior art, the oblate broke or stuck to the oral cavity and could not be swallowed, and when mixed with soft drink, the volume became too large or the taste became unpleasant and left uneaten. There was such a problem.
【0004】[0004]
【課題を解決するための手段】 ペースト状にするため
の基剤(例えば高粘度タイプのヒドロキシプロピルメチ
ルセルロース、ゼラチン、でんぷん、デキストラン、ア
ルギン酸塩、カゼインナトリウム、フィブロイン、ポリ
エチレングリコールなど)に必要に応じて粘稠度調節剤
(例えば軽質無水ケイ酸、グリセリンなど)、矯味剤
(例えばショ糖、ブドウ糖、ステビア、アスパルテー
ム、サッカリン、クエン酸など)、芳香剤(例えばオレ
ンジフレーバー、イチゴフレーバー、コーヒーフレーバ
ーなど)、および防腐剤(例えばパラオキシ安息香酸エ
チル、パラオキシ安息香酸メチル、パラオキシ安息香酸
プロピル、パラベン類、ソルビン酸類など)、着色料な
どを添加、混合して本発明のペースト状オブラートを調
製し、その適量を内用薬に添加、混合する。[Means for Solving the Problems] A base for making a paste (eg, high-viscosity type hydroxypropylmethylcellulose, gelatin, starch, dextran, alginate, sodium caseinate, fibroin, polyethylene glycol, etc.) is added as necessary. Consistency modifiers (eg light anhydrous silicic acid, glycerin etc.), flavoring agents (eg sucrose, glucose, stevia, aspartame, saccharin, citric acid etc.), fragrances (eg orange flavor, strawberry flavor, coffee flavor etc.) , And a preservative (for example, ethyl paraoxybenzoate, methyl paraoxybenzoate, propyl paraoxybenzoate, parabens, sorbic acid, etc.), a colorant, etc. are added and mixed to prepare the pasty wafer of the present invention, and an appropriate amount thereof is added. Internal medicine Add to and mix.
【0005】[0005]
【作用】 内用薬の口腔内における流動性(滑り)の改
善、および味、臭いなどのマスキング。[Function] Improvement of fluidity (slippage) in the oral cavity of an internal medicine and masking of taste, smell and the like.
【0006】[0006]
第1例 ペースト状にするための基剤として高粘度タイプのヒド
ロキシプロピルメチルセルロースを用い、これに粘稠度
調節剤として軽質無水ケイ酸を添加した。配合比はヒド
ロキシプロピルメチルセルロース:軽質無水ケイ酸:水
=1:0.5:40とし、さらに防腐剤としてパラオキ
シ安息香酸エチルを0.005%、矯味剤としてサッカ
リンナトリウムを0.012%、芳香剤としてオレンジ
油を0.75%添加して本発明のペースト状オブラート
を調製した。その5gを苦みと臭いの強い散剤1.3g
(消化薬)に添加、混合して服用させた。 第2例 ペースト状にするための基剤としてゼラチンとグリセリ
ンの混合物であるグリセロゼラチンを用いた。ゼラチ
ン:水:グリセリン=5:20:75の組成とし、さら
に防腐剤としてパラオキシ安息香酸エチルを0.005
%、矯味剤としてサッカリンナトリウムを0.012
%、芳香剤としてオレンジ油を0.75%添加して本発
明のペースト状オブラートを調製した。その5gを苦み
と臭いの強い散剤1.3g(消化薬)に添加、混合して
服用させた。First Example A high-viscosity type hydroxypropylmethylcellulose was used as a base material for forming a paste, and light anhydrous silicic acid was added to this as a viscosity adjusting agent. The compounding ratio was hydroxypropylmethylcellulose: light anhydrous silicic acid: water = 1: 0.5: 40, and 0.005% ethyl paraoxybenzoate as a preservative, 0.012% sodium saccharin as a flavoring agent, and an aromatic agent. 0.75% of orange oil was added to prepare the pasty wafer of the present invention. 1.3g of powder with strong bitterness and odor
It was added to (digestive), mixed and taken. Second Example Glycerogelatin, which is a mixture of gelatin and glycerin, was used as a base for forming a paste. Gelatin: water: glycerin = 5: 20: 75, and ethyl paraoxybenzoate 0.005 as a preservative.
%, 0.012 saccharin sodium as a corrigent
%, And 0.75% of orange oil as a fragrance were added to prepare the pasty wafer of the present invention. 5 g thereof was added to 1.3 g (digestive) of powder having a strong bitterness and odor, mixed, and taken.
【0007】[0007]
【発明の効果】 内用薬の口腔内における流動性(滑
り)が改善され飲み下すのが容易になった。内用薬の味
や臭いなどがマスキングされ飲み易くなった。また、混
合後の医薬品の容量があまり増えず、しかも少量ずつ服
用できるので飲み残しがなくなった。EFFECTS OF THE INVENTION The fluidity (slippage) of the internal medicine in the oral cavity was improved and it became easy to swallow. The taste and smell of the internal medicine were masked, making it easier to take. In addition, the volume of the medicine after mixing did not increase so much, and since it could be taken in small amounts, there was no leftover drink.
Claims (1)
くするための添加剤1. An additive for making it easy to take by mixing with an internal medicine to form a paste.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP34084794A JP3294033B2 (en) | 1994-12-24 | 1994-12-24 | Oblate |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP34084794A JP3294033B2 (en) | 1994-12-24 | 1994-12-24 | Oblate |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH08175971A true JPH08175971A (en) | 1996-07-09 |
JP3294033B2 JP3294033B2 (en) | 2002-06-17 |
Family
ID=18340858
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP34084794A Expired - Lifetime JP3294033B2 (en) | 1994-12-24 | 1994-12-24 | Oblate |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP3294033B2 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6277395B1 (en) | 1998-07-31 | 2001-08-21 | Ryukakusan Co. Ltd. | Swallowing-assistive drink |
JP2002512953A (en) * | 1998-04-29 | 2002-05-08 | 住友製薬株式会社 | Oral formulation of biguanide drug |
USRE39125E1 (en) * | 2000-03-13 | 2006-06-13 | Ryukakusan Co. Ltd | Swallowing-assistive drink |
JP2010195839A (en) * | 1998-04-29 | 2010-09-09 | Dainippon Sumitomo Pharma Co Ltd | Orally administered preparation of biguanide-based medicine |
-
1994
- 1994-12-24 JP JP34084794A patent/JP3294033B2/en not_active Expired - Lifetime
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002512953A (en) * | 1998-04-29 | 2002-05-08 | 住友製薬株式会社 | Oral formulation of biguanide drug |
JP2010195839A (en) * | 1998-04-29 | 2010-09-09 | Dainippon Sumitomo Pharma Co Ltd | Orally administered preparation of biguanide-based medicine |
US6277395B1 (en) | 1998-07-31 | 2001-08-21 | Ryukakusan Co. Ltd. | Swallowing-assistive drink |
USRE39125E1 (en) * | 2000-03-13 | 2006-06-13 | Ryukakusan Co. Ltd | Swallowing-assistive drink |
Also Published As
Publication number | Publication date |
---|---|
JP3294033B2 (en) | 2002-06-17 |
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