JPH08154902A - Noninvasively continuously sugar value measuring apparatus - Google Patents

Abstract

PURPOSE: To enable measuring of a sugar value continuously without inflicting pains on a patient by a method wherein a dilution liquid is fed with a feed liquid pump to a sensor section containing a glucose sensor, a suction tissue liquid is measured with a sample measuring section and an output signal of the sensor is inputted into data processing control section to be displayed. CONSTITUTION: A sample measuring section 5 is mounted on skin and a suction is performed by a suction pump 2. A sensor section 6 is filled with a dilution liquid by a feed liquid pump 4 beforehand. Then, a fixed amount of a suction tissue liquid is fed into the sensor section 6 together with the dilution liquid by a constant amount feed liquid pump 3 to dilute the suction tissue liquid in the sensor section 6. Then, a glucose sensor is caused to react with glucose and an output signal proportional to the concentration of the glucose is fetched into a data processing control section 1. The data processing control section 1 performs a control of a suction pump 2, the constant amount feed liquid pump 3 and a feed liquid pump 4, a control of a motor for rotating a measuring valve 9, an A/D inputting of an output of the glucose sensor and a treating for the conversion of a sugar value.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to blood glucose level measurement, and more particularly to a device for continuously measuring blood glucose level by collecting aspiration tissue fluid.

[0002]

2. Description of the Related Art Conventionally, a diabetic patient collects blood several times a day, puts the blood in a test device to measure the blood sugar level, and manages the time-dependent change of the blood sugar level.

[0003]

In the conventional blood sugar level control method, since blood is collected by a syringe, there is a problem that the patient is distressed by the invasion of the skin. Further, since it is difficult to measure continuously, there is a problem that it is not easy to know the change with time of blood glucose level.

[0004]

[Means for Solving the Problem] When negative pressure suction is applied to the skin,
Although a suctioned tissue fluid containing glucose in proportion to the blood glucose level can be obtained, the non-invasive continuous blood glucose level measurement system of the present invention sucks the suctioned tissue fluid, and in order to automatically measure the blood glucose level, a suction pump and a glucose sensor are used. The built-in sensor unit, the liquid feed pump that feeds the diluent to the sensor unit, the sample weighing unit that weighs the aspirated tissue fluid, the quantitative liquid feed pump that feeds the aspirated tissue fluid to the sensor unit, and controls the entire system. , And a data processing control unit for inputting and displaying the output signal of the sensor.

[0005]

The present invention will be described below with reference to the drawings. FIG. 1 is a block diagram of an embodiment of the present invention. The sample weighing unit 5 is attached to the skin, and the suction pump 2 sucks negative pressure. The sensor unit 6 is previously filled with the diluting liquid in the diluting liquid unit 7 by the liquid feeding pump 4. After the suction is started, the suctioned tissue fluid necessary for the measurement can be obtained in several tens of minutes, so that the fixed amount of the suctioned tissue fluid together with the diluting liquid is sent to the sensor unit 6 by the quantitative layer liquid pump 3. The suctioned tissue fluid is diluted in the sensor unit, the glucose sensor incorporated therein reacts with glucose contained in the suctioned tissue fluid, and an output signal proportional to the glucose concentration is taken into the data processing control unit 1. Has become. The data processing control unit includes a suction pump, a fixed-quantity liquid feed pump, a liquid feed pump ON,
The OFF control, the control of the motor 10 for rotating the weighing valve 9 incorporated in the sample weighing unit, the A / D input of the glucose sensor output, and the blood glucose conversion are performed.

FIG. 2 shows a sectional view of the sample weighing section. The sample weighing unit is attached so as to be in close contact with the skin 11. First, when the weighing valve 9 is set in the vertical direction and suction is started, suction is performed in the direction of the arrow, and the suctioned tissue fluid 12 is eventually obtained in the weighing valve. Next, set the weighing valve to the motor 10
To set in the horizontal direction by rotating in the direction of arrow d. Here, when a fixed amount of liquid is fed from the direction of the arrow b by a fixed amount, the suctioned tissue fluid is pushed out in the direction of the arrow c and reaches the sensor unit. After this, the weighing valve is returned to the vertical direction again, and suction is restarted. By repeating the above operation, it is possible to measure the blood glucose level at regular time intervals.

FIG. 3 is a diagram showing a basic flow chart of this apparatus system. When the power is turned on, the program of the data processing control unit starts, the suction pump is driven, and suction is started. After several tens of minutes, visually confirm whether the aspirated tissue fluid was collected. If the aspirated tissue fluid is sufficiently collected, the data processing control unit is operated, the weighing valve is rotated, and the aspirated tissue fluid is sent to the sensor unit. The measurement is started immediately after the liquid is sent, the output signal of the glucose sensor is input to the data processing control unit, and the glucose value is converted and displayed. After the measurement is completed, the sensor unit is washed with the liquid feed pump to prepare for the next measurement. The data processing control unit monitors the clock so that it can be measured at regular time intervals,
It has a function of displaying a message prompting the next measurement at the designated time. By repeating the measurement, washing, and time monitoring as described above, it is possible to continuously measure the blood glucose level from the aspirated tissue fluid.

[0008]

As described above, according to the present invention, a series of operations for automatically collecting, weighing, measuring and washing aspirated tissue fluid that does not require blood sampling are integrated, so that the blood glucose level can be continuously measured. Has the effect that it is possible.

[Brief description of drawings]

FIG. 1 is a block diagram of one embodiment of the present invention.

FIG. 2 is a sectional view of a sample weighing unit.

[Fig. 3] System flow chart

[Explanation of symbols]

 1 Data processing control unit 2 Suction pump 3 Fixed amount liquid feeding pump 4 Liquid feeding pump 5 Sample weighing unit 6 Sensor unit 7 Diluting liquid unit 8 Waste liquid unit 9 Weighing valve 10 Motor 11 Skin 12 Suction tissue liquid

Claims (1)

[Claims] 1. A suction pump for sucking a negative pressure on the surface of the skin, a sensor unit containing a glucose sensor, a liquid feed pump for feeding a diluent to the sensor unit, and a sample weighing unit for weighing aspiration tissue fluid. A non-invasive continuous blood glucose level measuring device, comprising: a fixed-quantity liquid-feeding pump that feeds aspirated tissue fluid to a sensor unit; and a data processing control unit that controls the entire system and inputs and displays an output signal of the sensor.