JPH0789814A - Agent for preventing removing aquatic injurious organism adhesion - Google Patents

Abstract

PURPOSE:To provide the subject agent maintaining marine injurious organism adhesion-repelling effect at least comparable to the case in which a conventional heavy metal compound is used, and safe for both human bodies and environments. CONSTITUTION:The subject agent contains as an active ingredient 3- acetoxypukalide of the formula, which is obtained by extracting Sinularia sp., a kind of Octactiniaria, etc., and subsequently purifying the extract. The agent is prepared in the form of a coating, a solution or an emulsion and subsequently used. Therein, the compound of the formula is compounded in an amount of 1-45wt.%, preferably 5-20wt.%, in the case of the coating, 2-40wt.%, preferably 5-20wt.%, in the case of the solution prepared together with a coating film- forming agent, or 5-50wt.%, preferably 10-20wt.%, in the case of the the emulsion.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to the bottom of ships, fishing nets for aquaculture and stationary, equipment placed under the sea such as buoys, condenser cooling water for nuclear power and thermal power plants, or heat exchanger cooling for the petrochemical industry. The present invention relates to a novel agent for controlling harmful organisms in water that prevents harmful marine organisms from adhering to and multiplying intake channels of water.

[0002]

2. Description of the Related Art Barnacles, oysters, mussels, hydras, serpras, squirts, and sea squirrels are used in parts that are constantly in contact with seawater, such as the bottom of ships, underwater structures, and intake channels for cooling water.
Shellfish and algae such as bryozoans, sea lettuce, sea bream, and green algae attach and grow. These organisms cause an increase in fluid resistance by attaching to the bottom of ships, resulting in loss of fuel. Further, if it adheres to the cooling equipment part, it causes a decrease in thermal conductivity, which reduces the capacity of equipment and the like, which causes great economic damage.

Conventionally, various control agents have been used in order to prevent such adhesion and overgrowth of marine pests. As active ingredients of such control agents, cuprous oxide, organotin compounds and the like are known and are still widely used. These active ingredients are contained in the paint in an amount of 10 to 50% by weight, and the active ingredients are applied to the bottom of a ship or the like and continuously eluted in seawater to prevent the attachment of pests.

[0004]

Recently, heavy metals and harmful elements pollute the environment such as rivers and seawater,
In addition, since it is a persistent compound or a highly accumulative compound, it may harm human health through the media of fish and shellfish.Therefore, guidance was given on the use of the most frequently used organotin compounds. It is the current situation. Therefore, there is an urgent need for the development of safe and effective active ingredients that replace conventional control agents.

[0005]

[Means for Solving the Problems] In view of such a current situation,
The present inventors have conducted intensive studies to develop a compound having a high safety and an excellent control effect, and as a result, found that 3-acetoxypcalide has a control effect against harmful marine periphytic organisms, and based on this finding Based on this, the present invention has been completed.

That is, the present invention is an agent for controlling harmful organisms in water, which comprises 3-acetoxypcalide represented by the formula (I) as an active ingredient.

[0007]

[Chemical 2]

3-Acetoxycuprate is a known compound (BFBowden, JCColl, and ADWright: Aus.
tJChem., 42 , 757-763 (1989)), for example, extracted and purified from Sinularia sp. The extraction solvent used here is generally an organic solvent, preferably acetone or ethanol. As the purification method, known methods such as partition purification and chromatography can be used, but silica gel chromatography using a mixed solvent of hexane and chloroform as an eluent is preferably used. Also,
In addition to the method of extracting from the organism as described above, it can be chemically synthesized.

3 used as an active ingredient in the present invention
The acetoxypcalide may be used alone or in a mixture with other controlling agents. The control agent of the present invention is used by being prepared in the form of paint, solution, emulsion, etc.,
These formulations can be carried out without any problem by using a commonly used general formula. For example, when used as a paint, the above-mentioned active ingredient can be mixed with a paint composition to prepare an antifouling paint, which can be applied to the bottom of the ship, the undersea structure and the cooling water intake passage. The antifouling paint is prepared by mixing the active ingredient, a film-forming agent, and a general solvent, extender pigment, coloring pigment, and additive as desired. Examples of the coating film forming agent used at this time include chlorinated rubber resins, vinyl acetate resins, acrylic resins and natural resins. In this case, the active ingredient is blended in a proportion of 1 to 45%, preferably 5 to 20% based on the weight of the coating material.

When the control agent of the present invention is used as a solution, for example, the active ingredient is mixed with a film-forming agent and dissolved in a solvent to prepare a solution, which is used for the purpose of preventing the adhesion and growth of marine organisms. , Can be applied to stationary fishing nets. The coating film forming agent used at this time includes, for example, chlorinated rubber resin, vinyl acetate resin, acrylic resin, natural resin and the like, and the solvent includes toluene, xylene, cumene, methyl isobutyl ketone and the like. If necessary, additives such as a plasticizer can be added to the solvent. When used as a solvent, the active ingredient is 2-40% by weight, preferably 5-20% by weight, based on the weight of the solution.
It is mixed in the ratio of.

When used as an emulsion, the active ingredient is dissolved in a solvent, and a surfactant is further added to prepare an emulsion by a conventional method. As the surface active agent, a generally used one can be used. When used as an emulsion, the active ingredient is incorporated in an amount of 5 to 50% by weight, preferably 10 to 20% by weight, based on the weight of the emulsion. The control agent of the present invention can also be used by kneading it into a polymeric resin material such as a fishing net or a material for undersea use such as concrete.

Hereinafter, the present invention will be described in detail with reference to Examples, but the scope of the present invention is not limited to these Examples.

[0013]

【Example】

Example 1 Sinulari corals collected in Palau
a sp.) was shredded, 500 ml of acetone was added, and the components were extracted at room temperature. The extract was filtered to remove the residue, and the filtrate was concentrated under reduced pressure at room temperature to remove acetone.
To this, 250 ml of ethyl acetate and 250 ml of water were added and distributed, and the upper layer, ethyl acetate, was separated and distilled off at room temperature under reduced pressure to obtain 2.7 g of an oily substance. This oily substance was subjected to silica gel chromatography (eluent: a mixture of chloroform and hexane 4: 1) and chromatography using Sephadex LH20 (eluent: a mixture of chloroform and hexane 4: 1). 135 mg of an oil containing acetoxypcalide was obtained. This was purified by high performance liquid chromatography (eluent: 90% methanol, column: 10 × 25 cm reverse phase column), and 3-
About 19 mg of acetoxypcalide was obtained as a powder.

Regarding this 3-acetoxypcalide,
The anti-adhesion effect was examined using the most important adherent organism, Taedema barnacle larvae. That is, 0.
Dissolve 005 mg in 0.1 ml of methanol, apply it evenly on a circular petri dish with a diameter of 4 cm, dry the methanol,
Furthermore, 5 ml of filtered seawater and the larvae of the adhering stage of Tatemima barnacle 10
The animals were placed and left in the dark at 23 ° C. Take out after 24 hours,
The number of barnacles that had undergone adhesion transformation on the bottom surface of the petri dish was examined to determine the adhesion prevention effect.

A similar test was conducted using TBTO (bistributyltin oxide). The test was repeated 3 times and the average was obtained. As a result, it was found that the compound of the present invention has the same effect as that of the conventional pest control agent for harmful adherence to water.

[0016]

[Table 1] ─────────────────────────── Adhesion rate (%) of the test compound barnacles ────────── ────────────────── 3-acetoxypcalide 0 TBTO 0 No treatment 85 ───────────────────── --Example-- (Example 2) An example of prescription when the control agent of the present invention is used as an antifouling paint is shown below.

[0017]

[Table 2] ────────────────────── Composition weight% ──────────────────── Inventive Compound 15 Rosin WW 6 VYHH (Vinyl Synthetic Resin) 6 Tricresyl Phosphate 2 Talc 15 Barium Sulfate 15 Rouge 10 Xylene 26 Methyl Isobutyl Ketone 5 ─────────────── ──────── Total 100 ──────────────────────

[0018]

EFFECTS OF THE INVENTION The control agent of the present invention was found to be excellent in the effect of repelling harmful organisms adhering to marine organisms, and the use of this control agent has the same or higher effect as the conventional control method using a heavy metal compound, while suppressing the effects on human bodies And environmentally safe control technology is provided.

Claims (1)

[Claims] 1. An agent for controlling harmful organisms in water, which comprises 3-acetoxypcalide represented by formula (I) as an active ingredient. [Chemical 1]