JPH0740425A - Method and apparatus for molding liquid container by hollow molding, and molding of medical dissolving solution container - Google Patents

Abstract

PURPOSE:To insert an insert part in a parison directly or after heating to subject the parison to hollow molding and certainly integrate the insert part and the parison in such a state that a membrane is provided to the insert part. CONSTITUTION:In a method and apparatus for molding a liquid container by hollow molding, the insert part 4 to be inserted in a parison 1A is inserted in the parison 1A from below directly or after heating and the parison 1A is subjected to hollow molding in a mold 3 to insert the insert part 4 by one molding process and an insert part built-in type hollow product (medical dissolving soln. container) good in a bonding state can be obtained.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a device for molding a liquid container by hollow molding and a method for molding a medical solution container, and more particularly, to insert or insert an insert component into a parison for hollow molding. According to the present invention, the present invention relates to a novel improvement for ensuring a good connection between a parison and an insert part in a state where the insert part has a thin film, and obtaining a good-quality liquid container and medical solution container.

[0002]

2. Description of the Related Art Generally, among antibiotics and blood products,
Due to the problem of pharmaceutical stability, it is supplied to medical care as a solid preparation, dissolved immediately before use and administered intravenously as an injection.The drug dissolution work at this time is carried out by a drug vial sealed with a rubber stopper. The solution container and the solution container were communicated with each other by means of a hollow double-ended needle having blade edges at both ends. Therefore, in this communication work, if the rubber stoppers and the double-headed needles are exposed to the outside air, there is a risk that the medicine will be contaminated. Therefore, various medical containers have been proposed in which this communication work can be performed in a sealed system. For example, Japanese Examined Patent Publication (Kokoku) No. 3-49262 discloses a configuration in which a capsule containing a drug vial and a flexible solution container are connected by a conduit means, and the conduit means is provided with a communicating means. In addition, Japanese Patent Laid-Open No. 2-1277 discloses
A medical container is disclosed in which the communication mechanism is improved so that the communication operation can be performed easily and reliably. The present invention is
The present invention relates to a solution container as shown in FIG. 11 of Japanese Patent Application Laid-Open No. 2-1277, and as a typical method for manufacturing this type of container, Japanese Patent Application Laid-Open No. 19103/1992.
No. 2, JP-A-4-191033 and JP-A-1
There is an inflation method disclosed in Japanese Patent Laid-Open No. 185264, and in this inflation method, a die member (corresponding to an insert part) is attached to two film sheet materials or inflation tube materials, and heat sealing or high frequency sealing is performed as a post process. It was welded. Further, in the blow molding method disclosed in Japanese Patent Publication No. Sho 63-36781 and Japanese Unexamined Patent Publication No. 5-924479, the above-mentioned die member is attached to two sheet-shaped parisons or tubular parisons,
It was blow molded.

[0003]

Since the conventional method is configured as described above, the following problems exist. That is, in the case of the above-mentioned inflation method, in the method in which the die member and the film sheet material or the inflation tube material are joined by heat sealing or high frequency sealing, a welding defect of both easily occurs, and the manufacturing process is two steps of molding and welding. Was required, which increased manpower and time, resulting in higher costs. In addition, there is a risk that foreign matters and the like may be mixed in during the sealing work, and it is not suitable for chemicals. Further, in the case of the above-mentioned blow molding method, the mouthpiece member is attached to the parison or the tubular parison, and air is blown through the mouthpiece member to perform the hollow forming, so that a thin film is formed on the mouthpiece member. However, it has not been achieved that the requirements for maintaining the hermeticity and the requirements for forming a closed mouth on the mouthpiece member of the container are satisfied.

The present invention has been made to solve the above problems, and in particular, the insert part has a thin film by being directly or after being heated and then inserted into a parison to be hollow-molded. Molding method and device for a liquid container by hollow molding that ensures a good connection between the parison and the insert part in the state to obtain a good-quality liquid container and a medical dissolving liquid container, and molding of the medical dissolving liquid container The purpose is to provide a method.

[0005]

A method for molding a liquid container by hollow molding and a method for molding a medical solution container according to the present invention include sandwiching a parison from a crosshead with a mold and letting air inside the parison. In a method for molding a liquid container by hollow molding so as to obtain a hollow molded article by supplying, after heating an insert part for inserting into the parison, the insert part is inserted from below the parison, and the insert part is the parison. It is a method of hollow molding in the mold by supplying air from above the parison in a state of being inserted in the mold.

More specifically, it is a method of heating the inner surface and the outer surface of the insert part.

The method for molding a medical solution container according to the present invention is a hollow molding in which a parison from a crosshead is sandwiched between molds and air is supplied into the parison to obtain a medical solution container. In the method for molding a medical solution container, in a state where an insert part having a thin film is inserted from below the parison, air is supplied from above the parison to perform hollow molding in the mold, and to dissolve the medical solution. It is a method of forming a closed port and an opening at both ends of a liquid container.

In the molding apparatus for a liquid container by hollow molding according to the present invention, the parison from the crosshead is sandwiched by molds, and air is supplied into the parison to obtain a hollow molded product. In a container container forming apparatus, a moving body located below the mold and moving in synchronization with the mold, a heating body fixedly arranged on the moving body, and an elevating device provided on the moving body move up and down. And a component support portion for freely mounting an insert component, wherein the insert component is heated by the heating body and then inserted into the parison.

More specifically, a guide space for guiding a heat medium is formed in the component support part, and the heating element is arranged at an outer peripheral position of the component support part.

[0010]

In the method and apparatus for molding a liquid container by hollow molding and the method for molding a medical solution container according to the present invention, the insert part located below the mold is heated directly or after heating the inner and outer surfaces thereof. The insert part is inserted into the lower part of the parison that has drooped into the opened mold through the elevating device. Then, after closing the mold, the upper part of the parison is cut by a cutter and the mold is moved to below the air blowing nozzle. After that, drive this air blowing nozzle from above the parison to the top,
By supplying air into the parison, the parison in the heat state and the insert part in the room temperature or in the heated state are firmly connected to each other, so that the hollow molding and the insert of the insert part can be performed in one hollow molding process. Can be done at the same time. Therefore, when the insert part has a thin film inside, a liquid container or a medical solution container having the thin film can be obtained.

[0011]

The preferred embodiments of the method and apparatus for molding a liquid container by hollow molding and the method for molding a medical solution container according to the present invention will be described in detail below with reference to the drawings.
An extruder 2 is shown in FIG. 1 and FIG.
This crosshead is a crosshead connected to
An openable and closable mold 3 is disposed below the nozzle port 1a of the above, and a movable body 5 for moving the insert component 4 is provided below the mold 3.

The moving body 5 is constructed so that it can be moved synchronously with the movement of the mold 3 by a moving means (not shown). The moving body 5 holds the main body 6 and the insert part 4 provided on the main body 6. And a heating unit 9 fixed to the main body 6 and provided at an outer peripheral position of the insert component 4.

As shown in FIG. 7, the insert part 4 has an H-shaped cross section, and a thin film 4a is formed in the central diametrical direction. The lifting device 8 is, as shown in FIG.
The piston 8c is configured to vertically move air or oil through the first hole 8a and the second hole 8b.
The lower portion of the component support portion 7 is integrally connected to the upper portion of an upright rod 8d provided at c.

A small-diameter upper portion 7a of the component support portion 7
The insert component 4 is fitted in the guide gap 7b formed in the component support portion 7, and the partition plate 7c is inserted in the guide gap 7b.
Is provided by the partition plate 7c.
Is configured to form a longitudinal flow path as indicated by the arrow.

At the bottom of the parts support section 7, air,
Inlet 2 for supplying a temperature-controlled medium such as oil or water
0 and an outlet 21 are formed, and the heat medium supplied from the inlet 20 moves in the guide space 7b along the arrow and heats the inner surface of the insert component 4 through the ceiling portion 7d that joins with the insert component 4. is doing.

Next, the operation will be described. First of all,
As shown in FIG. 2, the insert part 4 is inserted into the upper part 7a of the part support part 7, and the temperature at which the surface of the insert part 4 can be fused by the heating body 9 (40 to 120 ° C., 94 ° C. as an example). ), The mold 3 moves to the position directly below the parison 1A hanging from the crosshead 1 in the open state. (The insert part 4 also moves together with the mold 3.)
In this case, the component support 7 is 1 at 40 to 120 ° C.
As an example, it is heated to 78 ° C. to heat the inner surface of the insert part 4. Therefore, this heating prevents the surface temperature of the insert component 4 from decreasing and the adhesive strength from decreasing. The insert component 4 is raised to a predetermined height (shown by the dotted line in FIG. 8) between the molds 3 by the elevating device 8 via the component support part 7. After the parison 1A hanging from above completely covers the insert part 4, the mold 3 is closed and the mold is closed and clamped. Therefore, the insert part 4 is the parison 1
It has been inserted from below A. The insert part 4 is pressure-bonded between the mold 3 and the part support part 7, and is fused with the inner surface of the parison 1A as shown in FIG. 4 and then cooled and solidified by the cooled mold 3 to form the mouth of the parison 1A. Insert molding of the part is performed. The insert part 4 is not heated and only the heat of the parison 1A is used.
It is also possible to bind to A.

Next, after performing the above-mentioned mold clamping, FIGS.
As shown in, the parison 1A has a crosshead 1 and a mold 3
After cutting the parison to a predetermined length by the parison cutting device 1B, the parison 1A is clamped by the mold 3 and the mold is moved to just below the air blowing nozzle 30 (shown in FIGS. 5 and 6). ) Do. (The insert part 4 also moves together with the mold 3.)

After the air blowing nozzle 30 descends from above the mold 3 and is driven into the upper part of the parison 1A, compressed air (4 to 5 kg / cm ² ) is blown into the parison 1A to make the parison 1A. Blow. The parison 1A is pressure-bonded to the inner surface of the mold 3 with compressed air (blow air) and cooled, and is hollow-molded in the shape of the cavity of the mold 3. After this cooling and solidification, air is discharged, the blowing nozzle 30 rises upward, and the mold 3 opens,
The hollow molded product in which the insert component 4 is inserted into one end of the parison 1A is taken out.

Therefore, by going through the above-mentioned steps, the parison 1A can be used upside down from that at the time of molding to obtain the hollow molded product 40 having the insert component 4 in the upper part. This hollow molded product 40 The lower portion 41A is attached with the chemical solution outlet 41 disclosed in FIG. 1 of Japanese Patent Laid-Open No. 2-1277. Further, as a practical use example, this hollow molded article 40 is connected via a liquid passage 44 to a capsule 43 having a liquid drug vial 42 containing a solid preparation, as shown in FIG.
By actuating the hollow needle 45 provided in the capsule 43 to break the thin film 4a of the insert part 4, the solid formulation in the drug vial 42 drops into the solution container 40, which is a hollow molded article, and the predetermined drug solution is obtained. Is what you can get. It should be noted that the tip end portion of the component support portion 7 supporting the insert component 4 has been described in the case where the temperature-controlled medium (hot water or hot oil) is flown inside, but it may be heated by another heating body. In addition, in the above-described embodiment, the hollow molded product 40
As described above, the case of the liquid container has been described, but as described above, the thin film 4A is provided in the insert part 4, and as shown in FIG.
Also, it can be manufactured as a medical solution container having a configuration having an opening 40N formed in the drug solution outlet 41. In addition, in the above-mentioned embodiment, the case where a heated medium is used as the temperature-adjusted medium has been described, but it is also possible to cool using a cooled medium.

[0020]

Since the method and apparatus for molding a liquid container by hollow molding according to the present invention is configured as described above, the following effects can be obtained. 1) Since it is possible to perform collective molding in the molding machine without manufacturing (bonding) the liquid passage portion in a separate process, the manufacturing process is shortened, manpower and time are reduced, and cost is reduced. 2) Since the resin temperature of the liquid container and the surface temperature of the insert part can be controlled uniformly, defective adhesion (defects, pinholes) can be prevented and quality can be improved. 3) Since the inserts can be collectively molded in a clean room, it is possible to prevent the risk of foreign matter from entering, and it is possible to obtain an optimum hollow molded product especially for chemicals. 4) Further, since the opening on the side used as the discharge port can also be blow-molded, the number of parts can be reduced as compared with the inflation method, and the manufacturing cost can be reduced. 5) In addition, since there are few bonding points with the parts, pinholes from the bonding points are reduced, and because of blow bonding, the production capacity is higher and the equipment cost of the machine is cheaper than the conventional inflation molding. 6) Furthermore, when a hollow molded article is used as a medical dissolution liquid container, the conventional inflation molded article becomes elongated, which makes it inconvenient for medical use and reduces the drop to the drip administration site. Although the injection pressure into the inside may be lowered and it may be difficult to inject, the container according to the present invention can have a short overall length and a large diameter shape, and even when used for intravenous drip, a sufficient drop is obtained. It is possible to obtain a reliable injection pressure.

[Brief description of drawings]

FIG. 1 is a front view showing a molding apparatus for a liquid container by hollow molding according to the present invention.

FIG. 2 is a side view of a main part of FIG.

FIG. 3 is a front view showing a hanging state of a parison.

FIG. 4 is a side view of FIG.

FIG. 5 is a front view showing the mold after the mold is closed.

FIG. 6 is a side view of FIG.

FIG. 7 is a cross-sectional view showing an insert part.

FIG. 8 is an enlarged cross-sectional view of the main part of FIG.

FIG. 9 is a front view showing a hollow molded product after molding.

10 is a cross-sectional view taken along the line AA of FIG.

FIG. 11 is a cross-sectional view showing a usage example of a hollow molded product.

[Explanation of symbols]

 1 Crosshead 1A Parison 3 Mold 4 Insert part 5 Moving body 7 Parts support part 7b Guide space 8 Elevating device 9 Heating body 40 Hollow molding (medical solution container) 40M Closing 40N Opening

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[Procedure amendment]

[Submission date] August 3, 1993

[Procedure Amendment 1]

[Document name to be amended] Statement

[Name of item to be corrected] Claim 5

[Correction method] Change

[Correction content]

[Procedure Amendment 2]

[Document name to be amended] Statement

[Correction target item name] 0009

[Correction method] Change

[Correction content]

More specifically, a guide gap for guiding a temperature-controlled medium is formed in the component support part, and the heating element is arranged at an outer peripheral position of the component support part. .

 ─────────────────────────────────────────────────── ─── Continuation of the front page (72) Hirofumi Sagawa Inventor Hirofumi Sagawa 2-2-1 Fukuura, Kanazawa-ku, Yokohama-shi Kanagawa (72) Inventor Hiroshi Iwano 2-chome Fukuura, Kanazawa-ku, Yokohama No. 1 Japan Steel Works (72) Inventor Koji Umekita 1658 Oshinohara, Yasu-cho, Yasu-gun, Shiga Prefecture Rushi Morishita Co., Ltd. Inside Shiga Factory (72) Satoshi Taguchi 1658 Oshinohara, Yasu-cho, Shiga Prefecture Rushi Morishita Shiga Factory Co., Ltd.

Claims (5)

[Claims] 1. A hollow in which a parison (1A) from a crosshead (1) is sandwiched by a mold (3) and air is supplied into the parison (1A) to obtain a hollow molded product (40). In the method of molding a liquid container by molding, after heating the insert part (4) for inserting into the parison (1A), the parison (1A) is inserted from below, and the insert part (4) is the parison. A method for molding a liquid container by hollow molding, characterized in that air is supplied from above the parison (1A) while being inserted into (1A) to perform hollow molding in the mold (3). 2. The method for molding a liquid container by hollow molding according to claim 1, wherein the inner surface and the outer surface of the insert part (4) are heated. 3. A parison (1A) from the crosshead (1) is sandwiched by a mold (3), and air is supplied into the parison (1A) to obtain a medical solution container (40). In the method of molding a medical solution container by hollow molding, the insert part (4) having the thin film (4a) is inserted from below the parison (1A), and air is supplied from above the parison (1A). Hollow molding in the mold (3), and forming a closed (40M) and an opening (40N) at both ends of the medical solution container (40) for medical dissolution by hollow molding. Liquid container molding method. 4. A hollow formed by sandwiching a parison (1A) from a crosshead (1) with a mold (3) and supplying air into the parison (1A) to obtain a hollow molded article (40). In a molding device for a liquid container by molding, a movable body (5) located below the mold (3) and moving in synchronization with the mold (3), and the movable body.
A heating element (9) fixedly arranged on (5), and a component support part for vertically mounting an insert component (4) which is vertically movable by an elevating device (8) provided on the moving body (5). (7), the insert part (4) is configured to be inserted into the parison (1A) after being heated by the heating body (9), for liquid by hollow molding Container forming equipment. 5. A guide space (7b) for guiding a humidity-controlled medium is formed in the component support part (7),
The apparatus for molding a liquid container by hollow molding according to claim 4, wherein the heating body (9) is arranged at an outer peripheral position of the component support section (7).