JPH0735322B2 - Tick control agent - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to a novel tick control composition and a tick control material.

[Conventional technology]

Mites can be said to inhabit indoor dust of general households, but in recent years, a large number of mites have been seen due to changes in housing and lifestyle. Conventionally, as a tick control agent against such indoor dust mites, for example, fenitrothion, phenthion, DDVP, phosphorus compounds such as diazinon, boxer, carbamate compounds such as NAC, and viresuloid such as resmethrin forte. The compound is known.

[Problems to be solved by the invention]

These known tick control agents are used by holding them on tatami mats or insect-proof paper for carpets, or by spraying or spraying them as they are, but they have the following disadvantages. That is, phosphorus-based tick control agent is highly toxic, has a bad smell, has the disadvantage of low effect on Dermatophagoides mite, pyrethroid-based tick control agent is expensive, the disadvantage that it is low effect on the mosquito mites. It also has various problems such as difficulty in use when these mite control agents are used in combination.

[Means for solving problems]

Therefore, the present inventor has conducted various studies to provide an inexpensive tick control agent having low toxicity and a wide mite control area, and as a result, 2,5-dichloro-4-bromophenol, N, N-
Dimethyl-N'-tolyl-N '-(fluorodichloromethylthio) -sulfamide, 2-phenyl-phenol,
Sodium-2-phenolate, 5-chloro-2-methyl-
We have found that 4-isothiazolin-3-one, 2-methyl-4-isothiazolin-3-one, benzimidazolyl-methyl-carbamate fulfill the above requirements.

That is, the present invention relates to 2,5-dichloro-4-bromophenol, N, N-dimethyl-N′-tolyl-N ′-(fluorodichloromethylthio) -sulfamide, 2-phenyl-phenol, sodium-2-phenyl. -Phenolate, 5-chloro-2-methyl-4-isothiazoline-3
-One, one selected from 2-methyl-4-isothiazolin-3-one, or 2,5-dichloro-4-bromophenol, N, N-dimethyl-N'-tolyl-N '-(fluorodichloromethylthio ) -Sulfamide, 2-phenyl-phenol, sodium-2-phenyl-phenolate, 5-chloro-2-methyl-4-isothiazoline-
3-Amine, 2-methyl-4-isothiazolin-3-one, benzimidazolyl-methyl-carbamate, and at least two species selected from the composition as an active ingredient, a tick control agent composition, and the composition The present invention relates to a tick control material, characterized in that:

The tick control composition of the present invention, as its active ingredient, 2,
5-dichloro-4-bromophenol (hereinafter referred to as CBP), N, N-dimethyl-N'-tolyl-N '-(fluorodichloromethylthio) -sulfamide (hereinafter referred to as TFS), 2-phenyl-phenol (hereinafter referred to as TFS) Written as OPP),
Sodium-2-phenyl-phenolate (hereinafter referred to as SPP), 5-chloro-2-methyl-4-isothiazoline-
3-one (hereinafter referred to as CIO), 2-methyl-4-isothiazolin-3-one (hereinafter referred to as MIO), benzimidazolyl-methyl-carbamate (hereinafter referred to as BIC), and any of six kinds, Any 5 of them, 4 of them, 3 of them, 2 of them, or CBP, TFS, OPP, SPP, CIO, MIO
By containing any one of the above, a very excellent tick control effect is exhibited. The target mites can be targeted in any kind, but in particular, leopard mites such as Dermatophagoides farinae and Dermatophagoides farinae, spider mites such as Plutella mites and mite spider mites, dust mites such as dust mite and house dust mite, dust mites, stag beetle mite, etc. , And animal parasitic mites such as house dust mites and triticum mites.

The mite control agent composition of the present invention can be used as it is, a composition containing the above-mentioned active ingredient, but usually, the composition containing the active ingredient is held in a liquid carrier and a solid carrier, and applied as necessary. Addition of film-forming agents, emulsifiers, dispersants, spreading agents, wetting agents, stabilizers, propellants, volatilization regulators, etc., oils, emulsions, wettable powders, sprays, aerosols, smoke agents, coating It can be used in the form of agents, powders, granules and the like. Examples of the liquid carrier include water and alcohols such as methyl alcohol, ethyl alcohol and isopropyl alcohol, ketones such as acetone, methyl ethyl ketone and cyclohexanone, ethers such as tetrahydrofuran, dioxane and dimethyl ether, hexane, kerosene, normal paraffin and solvent. Aliphatic hydrocarbons such as naphtha, aromatic hydrocarbons such as benzene and toluene, halogenated hydrocarbons such as dichloromethane and dichloroethane, esters such as ethyl acetate and butyl acetate, CFC solvents (CFC 113, CFC 114B2) , CFC 21, CFC 10 and the like). As the solid carrier, for example, silicic acid, carion, activated carbon, bentonite, diatomaceous earth, talc, clay, calcium carbonate, mineral powder such as ceramic powder, wood flour, soybean flour, wheat flour, plant powder such as starch, cyclodextrin. The inclusion compounds such as and the like can be mentioned.

As the coating film forming agent, cellulose derivative, vinyl resin, alkyd resin, urea resin, epoxy resin, polyester resin, urethane resin, silicon resin, acrylic resin, chlorinated rubber, polyvinyl alcohol, etc. As emulsifiers, dispersants, spreading agents, soaps, polyoxyethylene fatty alcohol ethers, polyoxyethylene alkyl allyl ethers, polyoxyethylene fatty acid esters, fatty acid glycerides, sorbitan fatty acid esters, sulfuric acid esters of higher alcohols, Examples of the surfactant include alkyl allyl sulfonate, and examples of the propellant include liquefied petroleum gas, dimethyl ether, fluorocarbon and the like. Further, as a volatilization regulator, sublimation carriers such as tricyclodecane, cyclododecane, 2,4,6-triisopropyl-1,3,5-trioxane and trimethylene norbornene, and paradichlorobenzene, naphthalene π-camphor and other sublimation insecticides It is also possible to use the agent for controlling the acarid-controlling composition as a sublimable solid agent, or to use empenthrin or DD.
A volatile insect repellent such as VP can be combined and used as a volatile tick control agent.

Further, the tick control composition of the present invention, various insect repellents,
A synergist, a pest repellent, a murine repellent, an antioxidant, an anti-decomposition agent, a bactericide, a fungicide, a fragrance, a coloring agent and the like can be added. As the insect repellent that can be incorporated, any of various chemicals conventionally used for exterminating pests can be used. Typical agents include 3-allyl-2-methylcyclopent-2-en-4-one-1-yl dl-cis / trans-chrysanthemate, 3-allyl-2-methylcyclopent-2- En-4-one-1-yl d-cis / trans-chrysanthemate, d-3-allyl-2-methylcyclopent-2-en-4-one-1-yl d-
Trans-chrysanthemate, 3-allyl-2-methylcyclopent-2-en-4-one-1-yl d-trans-chrysanthemate, N- (3,4,5,6-tetrahydrophthalimide) -Methyl dl-cis / trans-chrysanthemate, 5-benzyl-3-furylmethyl d-cis / trans-chrysanthemate, 5- (2-
Propagyl) -3-furylmethyl chrysanthemate, 3
-Phenoxybenzyl 2,2-dimethyl-3- (2 '
-2'-dichloro) vinylcyclopropanecarboxylate, 3-phenoxybenzyl d-cis / trans-
Chrysanthemate, α-cyanophenoxybenzyl isopropyl-4-chlorophenylacetate, d-3-
Allyl-2-methylcyclopent-2-en-4-one-1-yl d-trans-chrysanthemate, (S)
-Α-Cyano-3-phenoxybenzyl (1R · cis)-
3- (2 • 2-dichlorovinyl) -2 • 2-dimethylcyclopropanecarbochelate, (R • S) -α-cyano-3-phenoxybenzyl (1R • 1S) -cis / trans-3- (2・ 2-Dichlorovinyl) -2,2-dimethylcyclopropanecarbochelate, α-cyano-3
-Phenoxybenzyl d-cis / trans-chrysanthemate, 1-ethynyl-2-methyl-2-pentenyl cis / trans-chrysanthemate, 1-ethynyl-
2-Methyl-2-pentenyl 2,2-dimethyl-3-
(2-Methyl-1-propenyl) cyclopropane-1-
Carboxylate, 1-ethynyl-2-methyl-2-pentenyl 2,2,3,3-tetramethylcyclopropanecarboxylate, 1-ethynyl-2-methyl-2-
Pentenyl 2,2-dimethyl-3- (2,2-dichlorovinyl) cyclopropane-1-carboxylate, 0
-0-dimethyl 0- (2,2-dichloro) vinyl phosphate, 0-isopropoxyphenylmethyl carbamate, 0.0-dimethyl 0- (3-methyl-4-nitrophenyl) thionophosphate, 0.0 -Diethyl 0-2-isopropyl-4-methyl-pyrimidyl-
(6) -thiophosphate, 0.0-dimethyl S-
Examples include (1.2-dicarboethoxyethyl) -dithiophosphate and benzylbenzoate.

The amount of the active ingredient in the composition for controlling ticks of the present invention may be appropriately determined depending on its dosage form, application method, application site, etc., but when used in the form of a wettable powder or an emulsion, it is effective. When the component composition is used in an amount of 0.1 to 50% by weight and in the form of an oil agent or an aerosol, it is preferable that the active ingredient composition is 0.1 to 10% by weight, and the application amount is 1 m ² per area to be treated. It is desirable to have about 20 mg or more of the active ingredient composition and about 2 mg or more of the active ingredient composition per 1 m ^{2 of} application space.

The present invention also provides a mite controlling material in which the above-mentioned mite controlling composition is held on a substrate. The mite controlling material is used as a film, a sheet, a building / constructing material or the like having a mite controlling property by utilizing the characteristics of its base material.
Here, as the substrate, for example, polyethylene, polypropylene, nylon, polyvinyl chloride, polyvinylidene chloride,
Synthetic resin sheets such as polyester, animal and vegetable or inorganic fibrous sheets (paper, cloth, non-woven fabric, leather, etc.), mixed sheets of these synthetic resins and inorganic fibers or powder, or blended cloth,
Examples thereof include a mixed-spun cloth or non-woven cloth of the above synthetic resin and animal and vegetable fibers, a foil or film of a metal such as aluminum, stainless steel, or zinc, and a laminated sheet of the above various sheets. Further, as the above-mentioned base material, natural wood such as wood, pencil fern, cod, etc. used as a building / construction material and plastics such as vinyl chloride resin, chlorinated polyethylene, polyethylene, polypropylene and the like can be effectively used. The means for holding the mite controlling agent composition of the present invention on these substrates is not particularly limited, and may be applied, for example, by coating, impregnation, dropping, kneading, or the like. The amount to be retained is not particularly limited and can be appropriately determined,
Usually, when impregnating the above-mentioned substrate, the amount is preferably up to the saturated impregnation amount.

As a preferred embodiment of the mite controlling material of the present invention, a mite controlling carpet can be exemplified. The mite control carpet of the present invention has a mite control agent composition of the present invention having a liquid formulation on the front surface and / or the back surface of an ordinary carpet composed of, for example, a pile, a first base cloth, a backing agent and a second base cloth. Spray coating or prior to making the above carpet,
Pile, kneading the mite control agent composition of the present invention to at least one of the first base cloth and the second base cloth, to create a carpet using these, or a backing agent the mite control agent of the present invention It is obtained by mixing and using it to make a carpet according to a precoat method or a jute back method. The above-mentioned odor, the precoat method is a method of applying a backing agent in advance to fix the pile on the first base cloth, and then applying a backing agent to this treated portion and adhering the second base cloth. Say. The jute back method is a method in which a backing agent is applied to the first base cloth in which piles are woven, and the second base cloth is adhered. The mite-controlling carpet prepared as described above usually preferably holds about 0.5 to 200 g of the active ingredient composition per 1 m ² of the carpet area.

[Operations and Effects of the Invention] As described above, the mite control agent composition of the present invention is used for bedding such as tatami mats, carpets, floors, corridors, mattresses, sofas, duvets and pillows, closets, storages, and warehouses. Placed on, sprayed on,
If it is directly treated by a method such as spraying, coating, fuming, heat evaporation, etc., or if a mite controlling material in which the composition is held on a substrate is installed at the above-mentioned place, an excellent mite controlling effect is exhibited.

〔Example〕

 Hereinafter, examples of the present invention will be described in more detail.

Example 1. Efficacy against Dermatophagoides farinae Black fine paper (5 x 5 cm) is impregnated with an acetone solution of the test composition to a predetermined concentration. After removing the solvent, the impregnated paper was packed in a polyethylene bag (6 x 6
cm) and stick all four sides together. After 48 hours, life or death was judged under a stereoscopic microscope. The result was obtained as the mortality rate (%) by the Abbott correction of the following formula and is shown in Table 1.

x: Percentage of live insects in untreated plot y: Percentage of live insects in treated plot Resmethrin forte is known to be effective against Dermatophagoides farinae, but the mite controlling agent composition of the present invention showed efficacy equal to or higher than that of resmethrin forte.

Example 2. Efficacy against Phytophthora infestans A procedure similar to that in Example 1 was carried out, and life or death was determined 24 hours later. The results were obtained as the mortality (%) by Abbott correction as in Example 1, and are shown in Table 2.

Against the diamondback mite, the tick control composition of the present invention,
It was as effective as or better than resmethrin forte.

Example 3. Specifications No. A of Table 3 below for the purpose of insect repellent of carpet.
.About.N to produce a mite control material of the present invention in the form of a carpet.

The following tests were carried out on the mite control carpet samples No. A to N obtained above.

<Test method> Carpet sample Nos. A to N and a drug-untreated carpet (20 x 20 cm each) were placed in a container (41 x 31 cm) with a mite medium containing approximately 10,000 Kona leopard mite in the center.
(22 cm) After storing it in the bottom, store it at 25 ° C and 64% RH for 2 days, and then absorb the mites on the front or back of the carpet with a vacuum cleaner that holds two 200mesh nylon gooses in the suction tube connection part. It was Next, remove the nylon goose from the vacuum cleaner, brush off the mites in a 300 ml beaker containing 100 ml of Darling's solution, stir and transfer to a centrifuge tube, centrifuge at 1000 rpm, and place the supernatant on the paper. Transfer to a Buchner funnel and filter with suction. The number of living mites on this paper was counted, and the result was calculated as the mortality rate (%) from the following formula.

x: number of living mites in the drug-untreated carpet group y: number of living mites in the tick-controlling carpet group The above test was repeated 3 times, and the results are shown in Table 4 as an average value.

As shown in Table 4 above, each sample showed a sufficient tick control property.

Example 4 To 15 g of each of the following test composition samples No. A to G, a small amount of a fragrance and 20 ml of ethyl cellosolve were added, and odorless kerosene was further added to make 150 ml in total, and liquefied petroleum gas and dimethyl ether mixture. (1: 1 volume ratio) of 150 ml was filled in a pressure can for aerosol (content: 400 ml), attached to an injection device, and sealed to obtain a mite controlling agent composition of the present invention in the form of an aerosol agent.

Using each aerosol thus obtained, the effect of controlling ticks was tested in the same manner as in Example 1.

<Test method> Spray each aerosol onto high-quality paper (30 x 30 cm) for 3 seconds so that it is as uniform as possible, store at room temperature for 1 day, and then 5
It was cut out into a sheet of size 5 cm, and the effect of controlling ticks was tested according to the test method of Example 1 below.

The above test was repeated 3 times and the results are shown in Table 5 as an average value.

As shown in Table 5 above, each sample showed a sufficient tick control property.

Example 5. Nos. A to I of the sample mixed with the test composition in Table 6 below are non-woven fabrics (polyethylene-pulp, thickness 300 μm, area 1 m ² ).
Then, the test composition was impregnated with 1 g of the test composition and dried to obtain a sheet-like mites controlling material of the present invention.

This sheet was cut into 5 × 5 cm pieces, and the effect of controlling ticks was tested in the same manner as in Example 1.

As a result, it was possible to obtain almost 100% mortality in all the samples, and to show a sufficient tick control property.

Example 6. The test composition of the present invention used in Example 5 was pulverized after being sufficiently stirred and mixed with the same weight of silicon oxide to obtain a mite control agent composition of the present invention in a powder form. .

The thus obtained powder agent was tested for tick control effect by the following test method.

<Test method> After heating and killing straw cut into about 2 cm length, 5 g of it is put in a 100 ml Erlenmeyer flask, then 0.05 g of each powder agent is added and mixed, and the conditions of 25 ° C and 85-90% RH are applied. Save for 1 day. To this Erlenmeyer flask, about 400 sporeless mites were put, after storing for 2 days under the same conditions, surviving mites were chased by the heat chasing method, the number was counted, and the mortality rate was determined according to the test method of Example 3. It was calculated.

As a result, it was possible to obtain a mortality rate of almost 100% with any of the powder agents, and to show a sufficient tick control property.

Claims (4)

[Claims] 1. A 1,5-dichloro-4-bromophenol,
N, N-dimethyl-N'-tolyl-N '-(fluorodichloromethylthio) -sulfamide, 2-phenyl-phenol, sodium-2-phenyl-phenolate, 5-
Chloro-2-methyl-4-isothiazolin-3-one,
A mite controlling agent composition comprising, as an active ingredient, one selected from 2-methyl-4-isothiazolin-3-one. 2. A 2,5-dichloro-4-bromophenol,
N, N-dimethyl-N'-tolyl-N '-(fluorodichloromethylthio) -sulfamide, 2-phenyl-phenol, sodium-2-phenyl-phenolate, 5-
Chloro-2-methyl-4-isothiazolin-3-one,
A mite controlling composition comprising at least two kinds selected from 2-methyl-4-isothiazolin-3-one and benzimidazolyl-methyl-carbamate as an active ingredient. 3. 5-5-Dichloro-4-bromophenol,
N, N-dimethyl-N'-tolyl-N '-(fluorodichloromethylthio) -sulfamide, 2-phenyl-phenol, sodium-2-phenyl-phenolate, 5-
Chloro-2-methyl-4-isothiazolin-3-one,
A mite control material comprising a base material which holds a mite control agent composition containing, as an active ingredient, one selected from 2-methyl-4-isothiazolin-3-one. 4. A 2,5-dichloro-4-bromophenol,
N, N-dimethyl-N'-tolyl-N '-(fluorodichloromethylthio) -sulfamide, 2-phenyl-phenol, sodium-2-phenyl-phenolate, 5-
Chloro-2-methyl-4-isothiazolin-3-one,
Control of ticks, characterized in that a base material holds a mite control agent composition containing at least two kinds selected from 2-methyl-4-isothiazolin-3-one and benzimidazolyl-methyl-carbamate as an active ingredient. Material.