JPH07255436A - Complex beverage - Google Patents

Abstract

PURPOSE:To obtain a complex beverage without feeling any malodor or taste during the preservation or to the time of swallowing the beverage by mixing capsule grains, prepared by encapsulating a hardly drinkable oily substance due to an oily smell, etc., with an enteric or a sustained release hydrogel, with a tasting drinking material. CONSTITUTION:This complex beverage is obtained by mixing seamless capsule grains prepared by encapsulating an oily substance such as docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) or vitamin E, assuming an oily smell and offensive taste and hardly drinkable, with an enteric or a sustained release hydrogel with, a tasting drinking material such as green tea or a juice. A cross- linked substance of gelatin and carrageenan is preferred as the hydrogel.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a complex beverage, and more particularly to enteric-coated or sustained-release particles containing a physiologically active or flavoring oily substance as a core substance and other taste-imparting drinks. TECHNICAL FIELD The present invention relates to a composite beverage in which materials are mixed, and the present invention relates to a composite beverage that can be softened in water or liquid at the time of use to make it easy to drink and to be used for drinking.

[0002]

2. Description of the Related Art Beverages containing various oily substances have been developed. For example, (1) one in which the oily substance is encapsulated in gelatin, (2) one in which the oily substance is mixed directly with a beverage together with an emulsifier, and (3) one in which the oily substance is included in cyclodextrin, (4) ) Some include powders containing proteins such as albumin.

[0003]

As described above, beverages containing various oily substances have been conventionally developed.
These have their respective drawbacks and are not always satisfactory. That is, the product produced by the method (1) is not suitable as a drink because the capsule is large and it dissolves in water. In the method of (2), when docosahexaenoic acid (hereinafter referred to as DHA) or eicosapentaenoic acid (hereinafter referred to as EPA), which has a strong fish oil odor, is used as an oily substance, it becomes so tasty that it cannot be made into a beverage, and it is inconvenient. It is stable. Also, the product obtained by the method (3) has good stability when dried and has a hidden odor, but it dissolves instantly when water is added, and the oily substance has a bad taste and odor. The product obtained by the method (4) does not dissolve in water at all and precipitates, which is not preferable for the roughness of the powder.

The present invention has been made in view of the above problems relating to the prior art of beverages containing an oily substance,
Its purpose is to use oily substances such as DHA and EPA as core substances to make enteric-coated or sustained-release particles, which are not difficult to drink due to an oily odor or disagreeable taste, are excellent in preservability, and effectively ingest physiologically active ingredients. It is to provide a complex beverage that can.

[0005]

Means and Actions for Solving the Problems
As a result of repeated studies on the solution to the above-mentioned problems, attention was paid to mixing particles having a seamless capsule with an oily substance encapsulated with an enteric-coated or sustained-release coating base material and a palatable drinking material.

As a means for achieving the above object, the present invention uses an oily substance as a core substance, and the core substance is encapsulated by a coating substrate made of an enteric-coated or sustained-release hydrogel to form a seamless capsule. And a tasty drinking material.

[0007] Furthermore, a composite beverage characterized by mixing an oily substance as a core substance, particles obtained by mixing the core substance with an enteric-coated or sustained-release hydrogel and solidifying, and a taste-drinking material. Also, the above-mentioned problems can be achieved.

The particles having an oily substance as a core substance in the present invention are prepared by using an enteric or sustained-release hydrogel.
High content up to about 70-80%, diameter 0.5-5m
m small capsule particles, or mixed with the hydrogel to be solidified particles and dried to improve storage stability. The oily substance is spilled between them or is bitten by them, causing discomfort.

Therefore, in the present invention, the above-mentioned capsule particles and the like and other powdery or granular taste-drinking materials are mixed to form a complex beverage, and when this beverage is added to water at the time of use, the capsule is It is a drink with a new sensation with a transparent feeling, which is one that softens particles etc. to make it easier to drink, and one that mixes capsule particles etc. with a liquid tasteable drinking material to make it easier to drink. You can Then, although the conventional gelatin capsule dissolves in water, the capsule coating base material according to the present invention uses an enteric-coated or sustained-release hydrogel. It can be taken while being hidden, and the physiologically active ingredient can be effectively ingested. Further, in the flavor component, the content is not eluted at once in water but is gradually released, and the flavor can be drifted for a long time.

The oily substance used as the core substance in the present invention is an oily substance or powder having a physiological activity or a flavor or a water-soluble substance dispersed and suspended in oil, and particularly a water-soluble substance. In the case of 1, if the W / O type emulsion is formed, it can be contained in the particles in an amount of nearly 50%. The oily substance used as the core substance is most preferably a physiologically active substance, examples of which include DHA and EP.
A, β-carotene, vitamin E and the like, and examples of the flavoring oily substance include yuzu oil, coffee oil, mustard oil, horseradish oil and mint oil, but are not necessarily limited to these. is not.

As described above, particles having an oily substance as a core substance are made into particles by using an enteric-coated or sustained-release hydrogel. Here, the hydrogel will be described. According to the studies of the present inventors, it was found that cross-linking between hydrogels imparts new properties different from the original properties, and enteric-coated gels, high-melting-point gels, sustained-release gels, salt-resistant gels Although developed one after another, an enteric-coated gel and a sustained-release gel are used in the present invention.

For details of this gel, see Japanese Patent Application No. 5-
As proposed by No. 295013, a crosslinked product composed of a combination of gelatin and carrageenan is most suitable for producing the above-mentioned two kinds of gels used in the present invention. The mixing ratio can be in the range of 10: 1 to 50: 1, and the higher the ratio of carrageenan, the less soluble it is in water, and the ratio is 30: 1.
With the above, enteric property is also added. The higher the degree of cross-linking, the higher the molecular density and, as a result, the lower the gas permeability of oxygen and the like. When an unsaturated fatty acid such as DHA is used as a core substance, a mixing ratio of about 10: 1 to 20: 1 is preferable, and conversely, when the core substance is a flavor component, the content is once used. It is preferable that it has a sustained-release property such that it is gradually released instead of being eluted into
About 1 to 50: 1 is desirable.

Next, particles are produced from the above core substance and crosslinked hydrogel. For that purpose, a cross-linked hydrogel mainly composed of gelatin is used as an outer coat and is encapsulated by a double droplet method, or a core substance and a hydrogel are emulsified to prepare mixed particles by a single droplet method. In the latter method, it is possible to disperse a hydrophilic substance in oil and add it dropwise, but since part of the core substance is exposed on the surface, it has a drawback that it gives off a bad taste or oily odor, and promotes oxidation. . Therefore, it is preferable to make the seamless capsule by the double droplet method.

In this seamless capsule, the diameter of the double tube nozzle and the dropping speed are adjusted in consideration of the viscosities and surface tensions of both the core substance and the hydrocolloid that forms the outer skin,
It can be made as particles of 0.5 to 5.0 mmφ. The hydrocolloid solution of the outer skin is heated to about 80 ° C,
The core substance is at room temperature and is slightly heated during passage through the double tube and during encapsulation, but this is for a few seconds, and there is almost no risk of oxidation proceeding. The lower the core material viscosity and the lower the surface tension, the easier the encapsulation. When the oil is viscous, it is advisable to mix and use an oil having a low viscosity such as medium chain fatty acid. In this way, the viscosity and surface tension of the oil of the core substance are adjusted, and then the hydrocolloid aqueous solution which becomes the outer skin is selected as the mixing ratio of gelatin and carrageenan depending on the kind of the core substance and the purpose of use as described above.

The concentration of gelatin used in the present invention is 10 to 10.
20% is suitable, but if one example of using DHA as the core substance is shown, 120 g of gelatin and 6 g of carrageenan are weighed and mixed, and separately 30 g of citric acid and 50 g of sodium citrate are dissolved in water. Then, the aqueous solution and the gel material are mixed to adjust the pH to 4, and the mixture is heated at 100 ° C. for 1 to 2 minutes with sufficient stirring to dissolve it. After that, the temperature is 70-
The temperature is maintained at 80 ° C., and a seamless capsule manufacturing machine (SPHEREX manufactured by Freund Sangyo Co., Ltd.) is used to adjust the dropping speed to make seamless capsules. In this case, the content of the core substance can be up to about 70 to 80%.
Gelatin and carrageenan, which form the outer skin, have a pH of 3-5, 6
Crosslinking proceeds during holding at 0 to 90 ° C. for about 30 minutes, and the solidified capsule is enteric.

Next, the stability and masking effect of the seamless capsule produced under the above conditions and method will be described. Fig. 1 shows a seamless capsule containing DHA oil containing 27% of DHA (containing 0.3% of natural antioxidant) as a core substance and the same DHA oil used as the target group.
Peroxide value (PO) under conditions of ℃, 40% RH, 30 days
It is a graph which shows the result of having measured the change with time of V). In the figure, line a and line b are the target areas, line a is not wrapped,
b wire is aluminum packaged (without nitrogen substitution), c
Lines are seamless capsules without packaging, and d lines are seamless capsules wrapped with aluminum (without nitrogen substitution). As is clear from this diagram, the seamless capsule according to the present invention has high oxidative stability. Also,
The fragrance intensity when dissolved in 90 ° C. hot water was almost the same as the initial value after storing the oil containing yuzu as a core substance at room temperature and 40 ° C. for 1 year.

The thus-produced seamless capsule according to the present invention has a free-flowing surface and does not stick to each other when it is dried, although it contains about 70 to 80% of the core substance. Therefore, it can be stored alone or as a mixture with other powdery or granular tasting drinks. However, if ingested as it is, small particles are caught between the teeth, and the oily substance is spilled by being chewed, which causes discomfort. Therefore, by adding water, hot water or other liquid drinking material at the time of use, gelatin absorbs water, swells and is softened, and becomes extremely pleasant-feeling particles that float in water.

The present invention utilizes the above-mentioned properties of the seamless capsule to mix the particles of the seamless capsule with other taste-imparting drinking materials to form a composite beverage. Examples of the palatable drinking material used in the present invention include green tea, black tea, herbal tea, coffee, cocoa, milk and its fermented components, fruit juice, palatable drinking material such as vegetable juice such as green juice, and the like. , Granular or liquid, and an umami drinking material consisting of miso, soy sauce, soup, etc. in powder form,
A granular or liquid one can be used. And
A composite beverage is prepared by mixing these taste-drinking materials and seamless capsules containing a physiologically active or flavoring oily substance as a core substance. Then, as the other tasty drinking material, powder, granular or liquid of a blended beverage comprising citric acid, vitamin C, baking soda, sugar and electrolyte can be used. The blended beverage and the seamless capsule particles described above can be used. Is mixed to make a composite beverage.

Further, the composite beverage may be packaged in the form of a stick or the like if it is in the form of powder or granules, and may be put on the market or stored, and used as a functional beverage by dissolving it in water or warm water at the time of use. Further, in the case of a compounded beverage such as baking soda as a tasteable drinking material, which is a powdered or granular compounded beverage, an excipient or a binder is added to these to perform powder tableting, It can also be commercialized as an effervescent tablet. And for this tableting, 0.5-1.0 m
A seamless capsule having a small mφ is preferable.

[0020]

【Example】

Example 1. 5 g of carrageenan and 5 g of water in 100 g of gelatin.
Add 95 g and mix homogeneously, adjust pH to 4 and add 8
A crosslinked gel was prepared by stirring for 10 minutes while warming to 0 ° C. This crosslinked gel is used as a coating base material, and DHA oil (DHA
27%) was used as a core substance and was applied to a seamless capsule manufacturing machine (SPHEREX manufactured by Freund Sangyo Co., Ltd.) to prepare 80% DHA oil, and an enteric-coated seamless capsule having a particle diameter of 1 mm. Next, 1.4 g of this enteric seamless capsule (containing 300 mg of DHA) and 14.8 g of Pocari Sweat Powder manufactured by Otsuka Pharmaceutical Co., Ltd.
(0 ml) was mixed, placed in an aluminum packet and sealed, and subjected to an oven test at 40 ° C. and 70% RH for 1 month. As a result, the peroxide value (POV) of DHA oil is
It was 5 meq / kg or less, and stability was confirmed. Further, when this mixture was dissolved in 200 ml of water and drunk after 10 minutes, the seamless capsule was moderately soft and could be drunk without being bitten by the teeth.
When a seamless capsule with a particle diameter of 1 mm produced by the same method using only gelatin as a coating substrate was sampled, half of the DHA oil spilled out after 2 minutes of stirring with water, and the oil was used even after drinking. The odor and odor were very unpleasant.

Example 2 A seamless capsule was prepared in the same manner as in Example 1. Next, 1.4 g (containing 300 mg of DHA) of this enteric-coated seamless capsule was mixed with one tablet (4.6 g) of C-MAX (Seamax) 1000 manufactured by Otsuka Pharmaceutical Co., Ltd., which was crushed to obtain a tableting pressure of 1000.
Tablets were compressed with kg. The obtained tablets have a diameter of 2.5 cm,
The test piece having a height of 6 mm was put in an aluminum packaging and closed, and the same test as in Example 1 was performed. As a result, D
It was confirmed that the POV of HA oil was stable at 4.8 meq / kg. Further, when it was dissolved in water and drunk, the same results as in Example 1 were obtained.

Example 3 1.4 g of enteric coated seamless capsules manufactured in the same manner as in Example 1 (300 mg of DHA)
Content) and β-carotene 20 produced in the same manner
% Of 0.5% enteric coated seamless capsules was added to 200 ml of liquid Pocari Sweat manufactured by Otsuka Pharmaceutical Co., Ltd. and gelatin capsule seamless capsules of the same form were used at 20 ° C. Comparative observation was carried out for one month. The results are shown in Table 1.

[0023]

[Table 1]

As shown above, in the gelatin-coated product of the target area, all the capsules disintegrated within 10 days.
The enteric-coated product maintained the capsule form even after 30 days. Also, the POV of DHA oil in the enteric coated product after 30 days was measured and found to be 1.5 meq at the start of observation.
Although the value which was / kg increased to 3.4 meq / kg, it was confirmed to be stable even in the liquid because it was within the quality specification range.

Example 4 A seamless base material containing about 60% of a mint oil as a flavor component as a core substance and comprising gelatin and carrageenan as in Example 1 and being gradually released by adjusting the degree of crosslinking. Capsule (particle size 3mm) about 1g
Was mixed with 8 g of powdered black tea, placed in an aluminum packet and closed. After that, when the same test as in Example 1 was performed, the flavor component was sufficiently retained even after 1 month,
When the mixed powder was dissolved in 200 ml of water, a good scent of mint began to drift.

[0026]

INDUSTRIAL APPLICABILITY The present invention uses particles of an oily substance as a core substance, and the core substance is encapsulated with a coating base material of an enteric-coated or sustained-release hydrogel to form a seamless capsule. According to the present invention, the complex beverage or the oily substance is a core substance, and the particles are solidified by mixing the core substance with a similar hydrogel, and the flavoring material is mixed. Since even if an oily substance such as DHA or EPA is used as the core substance, the particles can be enteric-coated or sustained-released particles, it is not difficult to drink due to an oily odor or a bad taste,
It has excellent storability and can effectively ingest physiologically active ingredients and flavor ingredients. The following are specific effects.

(1) By encapsulating an oily substance having physiological activity as a core substance, a required amount can be easily ingested. (2) Oily core substances such as DHA and Vitamin E have an oily odor and a bad taste, and are difficult to swallow, but since they are wrapped in an enteric gel, they do not feel the smell or taste until they are stored or swallowed. There is no odor. (3) Even in the case where the core substance is an unsaturated fatty acid that is easily oxidized, by covering it with a gel having a high degree of cross-linking, it is possible to block oxygen permeation and stabilize it for a long period of time. (4) Since the capsule base material of the present invention is mainly composed of gelatin, it becomes hard when dried and has good storability. When this is put into water before use, the capsule absorbs water, swells and softens, and floats. The swollen and softened capsules are floating even if they are contained in the mouth, without being chewed by the teeth.
You can drink with a smooth throat. (5) Since the capsules do not dissolve in water or hot water of 60 ° C or lower, the contents do not leak into the beverage when the physiologically active ingredient having an oily odor or a bad taste is contained. (6) Since the capsules can be freely mixed in the beverage ingredients, it is possible to ingest a sufficient amount of several kinds of functional substances according to the purpose, as much as desired. (7) It is possible to provide products with new dosage forms and added value. (8) By setting the particle size of the capsule particles to 3 mm or less, the residence time in the stomach can be shortened and the transfer to the intestine can be made smooth. (9) When a flavor component is enclosed in the core substance, the scent can be retained for a long time and released at the time of use.

[Brief description of drawings]

FIG. 1 shows a seamless capsule containing DHA oil containing 27% of DHA as a core substance and the same DHA as a target group.
It is a graph which shows the result of having measured the change with time of peroxide value about oil.

[Explanation of symbols]

 a Target area, no packaging b Target area, aluminum-wrapped c Seamless capsule without packaging d Seamless capsule with aluminum packaging

Claims (4)

[Claims] 1. A particle comprising an oily substance as a core substance, the core substance being encapsulated by a coating base material comprising an enteric-coated or sustained-release hydrogel to form a seamless capsule, and a tasteable drink material are mixed. A complex beverage characterized by the following. 2. A composite beverage comprising an oily substance as a core substance, particles obtained by mixing the core substance with an enteric-coated or sustained-release hydrogel and solidified, and a taste-drinking material. 3. The complex drink according to claim 1, wherein the enteric-coated or sustained-release hydrogel is a cross-linked product of gelatin and carrageenan. 4. The oily core substance contains at least one selected from docosahexaenoic acid, eicosapentaenoic acid, β-carotene, vitamin E, yuzu oil, coffee oil, mustard oil, wasabi oil, and mint oil. The complex beverage according to 1 or 2.