JPH07173047A - Bath additive - Google Patents

Abstract

PURPOSE: To obtain a bathing additive containing a mixed aqueous solution of an amphoteric ion type substance derived from natural oils and fats, an anionic type substance and a nonionic type substance and an alcohol solution of medicinal plant extracts and capable of effectively treating dermatosis without exerting a bad influence on skin. CONSTITUTION: This bathing additive comprises (A) 85-95 wt.% mixture of an amphoteric type substance derived from vegetable and/or animal oils and fats (e.g. aminocarboxylate having betaine structure), an anionic substance (e.g. sulfate of an alkylpolyglycol ether) and/or a nonionic type substance (e.g. an aliphatic alcohol polyglycol ether derived from coconut oil), (B) 5-15 wt.% alcohol solution of medicinal plant extract of Achillea millefolium L., etc., and as necessary (C) 1.5 wt.% inorganic salt.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to bath additives based on vegetable and / or animal raw materials and the use of bath additives for the treatment of skin diseases.

[0002]

2. Description of the Related Art Skin diseases suffered by many people are classified into various types according to their causes. For example, inflammatory skin diseases caused by bacteria such as umbrellas, shingles, and scabs, protozoa, viruses, parasites, fungi, allergic or autoimmune skin diseases such as endogenous eczema, and psoriasis. Are classified as skin diseases of unknown cause.

[0003] In general, antifungal ointments are used for filamentous fungal diseases, bacterial and viral skin diseases, but they are irritating to the skin, and therefore, they may cause skin irritation. There is a problem that it adversely affects the acidic epidermal layer and receives new attacks from fungi and bacteria. In addition, cortisone-containing ointment is used for the treatment of psoriasis, or UVA irradiation is usually performed by applying a photosensitizer such as retinoid. According to these methods, the mineral balance is disturbed, the skin sags and becomes tense, and the skin is extensively damaged, but it works effectively in a short time, and a very large effect is obtained.

[0004]

However, since the treatment method using the above-mentioned agents has a non-negligible effect on the patients with skin diseases and the manufacturers of these agents, at present, agents using plants and animals as raw materials are used. Mild treatments using it are being studied.

US Pat. No. 4,581,230 discloses a cosmetic composition effective for hair and skin. This composition is prepared by dispersing flowers or leaves of constant particle size in an aqueous medium, and that the composition is effective for treating bacterial skin diseases and chronic endogenous skin diseases. There is no description suggesting.

The object of the present invention is therefore to provide a bath additive based on vegetable and / or animal raw materials, and the medicated water in which the bath additive is used, without adversely affecting the skin. It is an object of the present invention to provide a bath additive capable of effectively treating skin diseases.

[0007]

According to the invention, an aqueous solution of a mixture of zwitterionic, anionic and / or nonionic substances based on vegetable and / or animal fats and oils and one or more There is provided a bath additive based on a vegetable and / or animal raw material, characterized in that it contains an alcoholic solution based on a medicinal plant.

In one aspect of the invention, the bath additive comprises an aqueous solution of a surfactant based on vegetable and / or animal fats and an alcoholic solution based on one or more medicinal plants. Is. That is, the aqueous solution is a mixture of a surfactant and water added thereto.

In the present invention, at least one of a zwitterionic type substance, an anion type substance and a nonion type substance is used as the surfactant based on vegetable and / or animal fats and oils. As vegetable and animal fats and oils,
Those obtained from sebaceous glands of sheep, coco palm, castor and soybean are used. In the present invention, by forming a bath additive by using these aqueous solution and alcohol solution, it becomes possible to exert an antidote and to relieve inflammation. In addition, since it does not contain harmful chemical substances such as cortisone, it does not have a negative effect on mineral balance.

The bath additive of the present invention contains 85% aqueous solution of the above surfactant based on vegetable and / or animal fats and oils.
~ 95% by weight, 5% alcoholic solution based on medicinal plants
15% by weight, and up to 1.5% by weight of inorganic salts, especially 0.5
It is preferable that the content is from about 1.3% by weight.
In this composition, the viscosity is adjusted to a desired range and p
H is adjusted to a neutral to slightly acidic side that is preferable for the skin, and in addition to the synergistic effect of the surfactant, it acts so that the medicinal plant is well adapted to the skin.

In the above-mentioned bath additive, the inorganic salt acts as a thickener or a viscosity modifier, and sodium chloride is preferably used. The pH of the 1% aqueous solution of this bath additive is 6.5 to 7.5, especially 7.
It is preferably 3.

The aqueous solution of the surfactant used in the present invention has a solid content of 18 to 2 per the total amount of the aqueous solution.
Advantageously, 4% by weight, 4 to 8% by weight of solvent or solubilizer and 70 to 75% by weight of water are included. The solvent or solubilizer is for preventing the solid content from separating from water as flocs, for example, a lower alcohol is preferably used, and most preferably,
Ethanol or propanol having a purity of 90% by volume or more is used. These are advantageous in that they do not have the medical uncertainty inherent in other organic solvents. In the present invention, such a combination maximizes the effect on the skin by setting the composition of the aqueous solution within the range described above.

In the present invention, in order to further improve the above effects, the zwitterionic substance whose solid content of the aqueous solution based on animal and vegetable oils is 2 to 3% by weight, particularly 2.5% by weight, 11. 1 to 12.5% by weight, in particular 12.0% by weight, of anionic substances, and 4.8 to 5.9% by weight, in particular 5.5% by weight of nonionic substances. It is suitable. With such a composition and a water content of 73% by weight,
It is advantageous to use an aqueous solution with a solubilizer content of 5% by weight.

In another embodiment of the present invention, the bath additive has an aqueous solution content of 91 to 97 based on animal and vegetable fats and oils.
The content of alcohol solution based on medicinal plants is 0.
01-8 wt%, and up to 4 wt% inorganic salt content,
Especially, it is 2.7 to 3.8% by weight. As the animal and vegetable fats and oils used here, those mentioned above are exemplified, and they have substantially the same action as in the case of the above bath additives. In this case, the inorganic salt used as a thickener or viscosity modifier is preferably sodium chloride, and the pH of a 1% solution of this additive is preferably in the range of 6.8 to 7.4.

The aqueous solution used in this embodiment contains 3 to 7% by weight of zwitterionic substances, especially 4.8 to 6.5% by weight, 40 to 55% by weight of anionic substances, especially 43 to 49% by weight,
1 to 8% by weight of nonionic substance, particularly 3.8 to 6.5% by weight, 30 to 40% by weight of water, especially 33.5 to 38.5% by weight, and 1 to 5% of solvent or dissolution aid. % By weight, especially 2.
It is desirable to set it in the range of 5 to 4.2% by weight. The solvent or solubilizing agent is used to prevent the surface-active agent substance from becoming flocs and separating from water.
0 volume% or more of ethanol and isopropyl alcohol are preferably used.

In the present invention described above, an amino compound having an aminocarboxylate or betaine structure is used as the zwitterionic substance, an alkyl polyglycol ether sulfate is used as the anionic substance, and an aliphatic compound is used as the nonionic substance. Alcohol polyglycol ethers are used, all based on coconut oil. These substances are obtained from coconut oil fatty acid contained in palm and appropriately converted from it by a method known per se. These are physiologically and medically substantially harmless within the above-mentioned range.

In the present invention, examples of the zwitterionic substance obtained from coconut oil include alkyl-substituted ammonium betaine, betaine-type dicarboxyldiamine, and betaine-type fatty acid amide derivatives. As the anionic substance, C ₁₂ having an ethoxylation number of 2 to 3 is used.
Sodium salts of saturated fatty alcohol -C _14, can be exemplified saturated aliphatic alcohol polyglycol ethers of C ₁₂ -C ₁₄ ethoxylated number 4, 5 or 6. Here, as the above-mentioned zwitterionic substance, specifically,
Normal cocoalkyl dimethyl ammonium betaine, lauryl dimethyl carboxymethyl ammonium ammonium betaine, and dimethyl carboxymethyl coconut oil fatty acid propylamido ammonium betaine (Rewo Co., trade name: Rewoteric AM B 13) can be mentioned.
These are, like the above-mentioned commercially available anionic and nonionic substances, widely used in the pharmaceutical and cosmetic industries and have no physiological problem. Further, in the present invention, as the anionic substance, sodium lauryl ether sulfate (Rewo Co., Ltd., trade name: RewopolN
L 3) is preferable, and as the nonionic substance, lauryl alcohol polyglycol ether (trade name: Rewopal LA 6 manufactured by Rewo Co., Ltd.) is preferably used.

According to the invention, in order to moderate the inflammatory process caused by skin diseases and to neutralize the odors originating from the raw materials which form fats or oils, yarrow, oats and / or walnuts are produced by methods known per se. A plant extract obtained by glycol extraction from camomile is used. These active substances, namely vegetable essential oils, alkaloids, amino acids and glycosides are known to have bactericidal, analgesic and neutralizing effects in the field of phytotherapy.
In the above-described bath additive of the first aspect, the amount of each extract of yarrow, oat, and camilure used is 2 to 8% by weight based on the total amount of the bath additive. The amount of each extract used in the bath additive is 0.01 to 8% by weight, and this amount sets the concentration of the medicinal plant in the alcohol solution in each embodiment. Of course, it is within the scope of the present invention when vegetable oil is used instead of the alcoholic solution of the plant extract.

The bath additives based on animal and plant raw materials of the present invention are used in medicated hot water as a drug for treating bacterial and chronic endogenous skin diseases, preferably psoriasis. This bath additive is used alone or as an auxiliary agent in the medical treatment of skin diseases. Bath additive and water 1: 400
A solution consisting of an aqueous solution of about 96-98% by weight and an inorganic salt of about 1-4% by weight is about 1: 1000.
In the first embodiment used in a proportion of 99.98% by weight, a mixture of 90% by weight of the aqueous solution and 10% by weight of the medicinal plant extract is particularly suitable, and the bath additive and water are 1% by weight. In the second embodiment, used in a ratio of: 250 to 1: 800, 0.02 to 3% by weight of extracts of medicinal plants have proven suitable. 2 in the hot water mentioned above
By repeating the application for 5 to 30 minutes, the effect is exerted on 90 to 95% of all psoriasis.

[0020]

EXAMPLE A commercially available Camyrrhea extract in the amount shown in the following formulation and a part of lauryl alcohol polyglycol ether (ethoxylation number: 6) were mixed in an appropriate size at a ratio of 1:50 to 1: 100. The first solution was prepared by putting the mixture in the container No. 1 and stirring for 5 to 10 minutes.

Then, sodium chloride necessary for viscosity adjustment was completely dissolved in water (pure water) free of bacteria or tap water at 60 to 80 ° C. in an amount shown in the following formulation to prepare a second solution.

The first solution, the remaining amount of lauryl alcohol polyglycol ether, and the amount of isopropyl alcohol shown in the following formulation, commercially available dimethyl-carboxymethyl-coconut oil fatty acid propylamido ammonium betaine, sodium lauryl ether sulfate (ethoxylation number) :
3), and alternately placing the second solution in the third container,
A turbo stirrer or the like was used to stir at a power of 2 KW for about 10 minutes. Then, the obtained solution was allowed to stand for 18 to 24 hours, and then again stirred for 5 minutes using a turbo stirrer to thoroughly mix it. The bath additive of the present invention thus obtained,
It was packaged after the bubbles had completely disappeared.

Formulation: Camilure extract 0.03 g Lauryl alcohol polyglycol ether (Rewopal LA 6) 5.50 g Dimethyl carboxymethyl coconut oil fatty acid-propyl amide ammonium betaine (Rewoteric AM B 13) 6.00 g Sodium lauryl ether sulfate ( Rewopal NL 3) 45.00g Sodium chloride 3.5g Water (pure water) 36.97g

[0024]

EFFECTS OF THE INVENTION The bath additive of the present invention, whose constituent components are based on vegetable and / or animal raw materials, can effectively treat skin diseases without adversely affecting the skin. Become.

Claims (10)

[Claims] 1. An aqueous solution of a mixture of zwitterionic, anionic and / or nonionic substances based on vegetable and / or animal oils and fats and an alcoholic solution based on one or more medicinal plants. A bath additive based on vegetable and / or animal raw materials. 2. An aqueous solution based on vegetable and / or animal fats and oils in an amount of 85 to 95% by weight, an alcoholic solution based on a medicinal plant in an amount of 5 to 15% by weight, and an inorganic salt of 1.
The bath additive according to claim 1, which is contained in each proportion of 5% by weight. 3. The aqueous solution is 1 per total amount of the aqueous solution.
The bath additive according to claim 1 or 2, which comprises 8 to 24% by weight of solid content, 4 to 8% by weight of solvent or solubilizing agent, and 70 to 75% by weight of water. 4. The solid content of the aqueous solution is 2-3% by weight of a zwitterionic substance, 3-12.5% by weight of an anionic substance, and 4.8-5.9% by weight of a nonionic substance. Claim 3
The bath additive as described in 1. 5. An aqueous solution based on vegetable and / or animal fats and oils is 91 to 97% by weight, an alcoholic solution based on medicinal plants is 0.01 to 8% by weight, and further inorganic salts are up to 4% by weight. The bath additive according to claim 1, wherein the bath additive is contained in each proportion. 6. The aqueous solution comprises 3 to 7% by weight of a zwitterionic substance, 40 to 55% by weight of an anionic substance, and 1 to 8
6. The composition according to claim 1, which comprises 1% by weight of a nonionic substance and 30 to 40% by weight of water, and further contains 1 to 5% by weight of a solvent or a solubilizing agent based on the total amount of the bath additive. Bath additive. 7. The bath additive according to claim 3, wherein the solvent or the dissolution aid is a lower alcohol. 8. A zwitterionic substance obtained from fats and oils is an aminocarboxylate or an amino compound having a betaine structure, an anionic substance is a salt of alkyl polyglycol ether sulfate, and a nonionic substance is a coconut oil-based fat. The bath additive according to any one of claims 1 to 7, which is a group alcohol polyglycol ether. 9. An amino compound having a betaine structure is an alkyl-substituted ammonium betaine, and a salt of an alkyl polyglycol ether sulfuric acid is a sulfated C12-14 aliphatic having an ethoxylation number of 2 or 3. 9. The bath additive according to claim 8, which is a sodium salt of alcohol, and the aliphatic alcohol polyglycol ether is an aliphatic alcohol polyglycol ether having 12 to 14 carbon atoms and having an ethoxylation number of 4, 5 or 6. 10. The bath additive according to any one of claims 1 to 9, which contains a medicinal plant extract of Yarrow, Oat, and / or Camillele obtained by a method known per se.