JPH0713346U - Weak DC current carrying electrode useful for prevention and treatment of bacterial infection - Google Patents

Abstract

(57) [Abstract] [Purpose] Weak weak direct current is useful for prevention and treatment of bacterial infection in the living skin puncture part of medical catheter and living tissue in contact with the catheter. [Constitution] Consisting of jelly-like disinfectant mixed with carbon fiber (1), silver wire A (2) and adhesive tape (3), the silver wire is the non-adhesive surface (4) of the adhesive tape and the copper wire (5) An electrode having a structure connected to (first electrode). A silver wire (12) is wound around a CAPD (continuous peritoneal perfusion) catheter (11), and the silver wire is guided to the catheter tail (18) through the catheter wall (17) (second electrode). electrode). Using the above-mentioned first and second electrodes, weak direct current is applied to the living tissue between the first and second electrodes.

Description

Description: BACKGROUND OF THE INVENTION [0001] The present invention relates to the use of a catheter for a certain period of time in a living body, particularly in a blood vessel or abdominal cavity, from the skin surface of a living body for the purpose of medical treatment. Prevention and treatment of possible infection of the skin (22) that has been inserted with the catheter (infection at the insertion site) and infection of biological tissue in contact with the catheter (tunnel infection) that may occur due to spread of the infection at the insertion site. It is related to orthosis. [0002] Conventionally, when a catheter is inserted into a living body skin, it is disinfected daily with an antiseptic solution, and in some cases, a jelly-like disinfectant is further applied and then sterile gauze is applied. This was the only preventive measure against puncture site infection and tunnel infection. [0003] In addition, as a treatment method in the case of a puncture site infection or a tunnel infection, a disinfectant or an antibiotic is injected between the catheter and the living tissue from the catheter puncture site to disinfect or clean the infected site. The method was to administer antibiotics to the infected area, or systemically administer antibiotics (Reference 1). [0004] In addition to the purpose of fixing the catheter and the tissue in the CAPD catheter, a felt-like substance is fixed to a part of the catheter for the purpose of preventing tunnel infection from easily spreading into the abdominal cavity. Used the product. [0005] [Problems to be Solved by the Invention] [0005] The conventional catheters for indwelling blood vessels do not have highly effective preventive and therapeutic methods for puncture site infection and tunnel infection. [0006] Similarly, in the conventional CAPD catheter as well, there is no highly effective preventive method or therapeutic method for puncture site infection and tunnel infection. [0007] Further, for the purpose of preventing the tunnel infection from spreading into the abdominal cavity, when an infection occurs in the vicinity of the felt-like substance that is tightly fixed to the CAPD catheter, the abdominal wall is incised and the felt-like substance is removed. The infection in the area cannot be cured unless it is removed. [0008] Since the above-mentioned puncture site infection and tunnel infection promptly progressed and the discovery was delayed, a serious condition (bacteremia) in which bacteria entered the blood vessel or bacterial infection in the abdominal cavity. Severe, serious conditions (peritonitis) have occurred uncommonly (reference 1). According to the present invention, a weak DC current of about 10 microamperes (μA) is resident against bacteria, especially on the skin surface, and is frequently used as a pathogenic bacterium for puncture site infection or tunnel infection. Applying the fact that it has a high inhibitory effect against Staphylococcus aureus, and by using a silver electrode as a current-carrying electrode, it has a much higher inhibitory effect than antibiotics at concentrations normally used medically. By applying weak direct current to the site where the penetration site and the tunnel site, which are several centimeters from the catheter site, along the catheter, a weak direct current is applied. It prevents and treats with high efficiency (reference 2). In order to solve the above-mentioned object, first, the following two types of weak DC current-carrying electrodes (first electrode and second electrode) are used. The first electrode comprises a jelly-like disinfectant (1) mixed with carbon fiber, a silver wire A (2) and an adhesive tape (3), the silver wire A being the non-adhesive surface (4) of the adhesive tape.
And is connected to the conductor A (5) (FIGS. 1 and 2). [0012] The electric resistance of the jelly-like disinfectant mixed with carbon fiber is about 300Ω.
Since the adhesive tape adheres to the skin, the jelly-like disinfectant mixed with carbon fiber penetrates into the space between the skin and the catheter, centering on the skin piercing part of the catheter. It is possible to effectively energize the puncture portion, which is the most important point. When the second electrode is attached to the blood vessel placement catheter, it is often removed within a few days to a few weeks. Therefore, the silver wire B (7) should be adhered to the blood vessel placement catheter (6). After simply winding several times, it is guided to the catheter tail (9) as a silver wire (8) in the catheter wall for indwelling the blood vessel, and is connected to the lead wire B (10) from here (FIGS. 3 and 4). By doing so, it is possible to energize the electrodes attached to the catheter, and when the catheter is no longer needed, it is possible to quickly remove it. When the second electrode is attached to a CAPD catheter, it is often left semi-permanently unless infection occurs. Therefore, the silver wire C (12) is the first layer (13) for CAPD. The catheter (11) is tightly wound tightly and continuously, and the end is fixed so that the twisted silver wire cannot be unwound (14) (Fig. 5). The second and third layers are slightly roughened and wound so that a space is kept between the silver wires (15), and a loop (16) around which the needle thread passes.
After making several silver wires by twisting the silver wire, guide one end of the silver wire to the CAPD catheter tail (18) as the silver wire (17) in the CAPD catheter wall, and then connect it to the lead wire C (19). (Fig. 6). By doing so, the electrodes attached to the CAPD catheter can be easily energized, and a connective tissue of a living body is formed in the gap between the silver wires of the winding layers of the coarse silver wires of the second and third layers. A strong fixing effect can be obtained because it gets in and adheres to the silver wire. In a normal CAPD catheter, a felt-like substance is used in the peritoneal region (2
0) and the subcutaneous tissue part (21) are often attached at two places (Fig. 7), but the electrode of the present invention is usually attached to the CAPD catheter so as to correspond to the site of the subcutaneous tissue. In addition, electrodes can be attached to the catheter to fit the peritoneum (20) (FIG. 8). The first electrode is attached to the catheter insertion portion, and a weak direct current supply device is used between the first electrode and the second electrode to mainly prevent and treat the infection at the insertion portion. When the second electrode is attached to the blood vessel indwelling catheter, when the catheter is placed in the blood vessel from the skin surface, the electrode is located in the subcutaneous tissue portion, so that it is weak between the first electrode and the first electrode. By energizing DC, it mainly prevents and treats tunnel infection. When the catheter for indwelling a blood vessel becomes unnecessary, the catheter can be easily pulled out. When the electrode is attached to the CAPD catheter, a normal CAPD is used.
Similar to the catheter, skin incision and laparotomy are performed, the catheter is placed, and a weak direct current is applied to the second electrode. In addition, when tunnel infection occurs between the abdomen and subcutaneous tissue, a weak direct current can be applied between the electrodes placed in both. [Examples] [0021] Eight rabbits were used to experimentally investigate the effect of weak direct current application on the suppression of bacteria. For 4 rabbits, CAPD catheters with silver electrodes wrapped around the subcutaneous part and peritoneal part were inserted from the skin surface and left in the abdominal cavity, and then a weak DC current of about 10 μA was continuously applied for 1 week. Went to. For the other four rabbits, a CAPD catheter without electrodes was inserted from the skin surface and placed in the abdominal cavity as a control. When the number of white blood cells in the fluid stored in the abdominal cavity after one week was compared, it was found that the group to which a weak direct current was applied had a significantly lower white blood cell count and bacterial infection was suppressed. The silver electrode was considered to have silver chloride on the anode side and silver ions on the cathode side. No burn or other tissue reaction was observed in the tissue around the silver electrode. Effect of the Invention The first electrode acts as a suppressant against the progeny bacteria of the puncture site infection from the three points of the effect of the disinfectant, the effect of weak direct current application, and the effect of silver ion. When it is no longer needed or before the jelly-like disinfectant dries and the disinfecting effect decreases, a new electrode can be easily replaced. It is said that carbon fiber does not penetrate biological tissue and the biological reaction is similar to that of medical stainless steel, and when it is no longer needed, it can be easily removed together with the jelly-like disinfectant (Reference) References 3 and 4). Of the second electrodes, the electrode attached to the catheter for indwelling the blood vessel is difficult for the biological tissue to enter, so that the electrode can be easily removed when the catheter is no longer needed. Among the second electrodes, the electrode attached to the CAPD catheter is strongly fixed in the living body because adhesion with living tissue is likely to occur. Furthermore, if necessary, a thread for fixation can be passed through a ring made of silver wire to fix it to a part of the subcutaneous tissue (mainly the fascia), using the silver wire instead of the thread. Therefore, the risk of infection may be further reduced. Further, when the electrode is adhered to the peritoneum, the silver wires of the first layer are strong and are in contact with each other and wound around the catheter, so that the peritoneal fluid can be prevented from leaking from the periphery of the catheter. Furthermore, unlike the conventional felt-like substance that is in close contact with the conventional CAPD catheter, the silver electrodes are energized by a weak direct current, so infection is unlikely to occur. Further, by changing the polarity of the weak direct current conduction (whether it is the anode or the cathode) and conducting the electricity, the silver ion effect can be brought to either the first electrode side or the second electrode side. [0026] In addition, there is a report that the suppression of bacteria continues even after a weak DC current is applied, and it is considered that the weak DC current does not necessarily have to be continuously applied (Reference 2).

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a plan view of a first electrode. FIG. 2 is a cross-sectional view of a first electrode. FIG. 3 is a cross-sectional view of the catheter portion when the second electrode is attached to the blood vessel placement catheter. FIG. 4 is a perspective view when a second electrode is attached to a blood vessel placement catheter. FIG. 5 is a perspective view in the middle of production when the second electrode is attached to the CAPD catheter. FIG. 6 is a perspective view when the second electrode is attached to the CAPD catheter. FIG. 7 is a vertical cross-sectional view of a conventional CAPD catheter indwelling from the skin (22) to the abdominal cavity (23). FIG. 8 is a vertical cross-sectional view when two second electrodes are attached to a CAPD catheter and left in the abdominal cavity (23) of the skin (22). [Explanation of Codes] 1 Jelly-like disinfectant mixed with carbon fiber 2 Silver wire A 3 Adhesive tape 4 Non-adhesive surface of adhesive tape 5 Conductive wire A 6 Catheter for blood vessel placement 7 Silver wire B 8 Inside catheter wall for blood vessel placement Silver wire 9 Catheter tail for blood vessel placement 10 Conductive wire B 11 CAPD catheter 12 Silver wire C 13 First layer of silver wire wound on CAPD catheter 14 Fixing by twisting 15 Second silver wire wound on CAPD catheter, Third layer 16 Ring 17 through which needle thread passes 17 Silver wire in CAPD catheter wall 18 CAPD catheter tail 19 Conductor C 20 Peritoneal part 21 Subcutaneous tissue part 22 Living skin 23 Abdominal cavity (reference) 1. Amano I, Inagaki Y: Continuous outpatient peritoneal dialysis, infection prevention and infection control. Blood purification method (first volume), p. 503-5
07, Japanese clinical 1991 extra number. 2. Haruhito Kamizono: On the Effect of Weak DC Current with Silver Electrodes on Bacteria, Nissei 64: 860-86
7, 1990. 3. Katahira Kiyoaki, et al .: Carbon fiber electrodes and pressure sensors. Medical electronics and biotechnology. 17 (Special issue): 582-5
83, 1979. 4. Shiraiwa Y, et al .: Electrode and pressure sensor for urethral EMG using carbon fiber. Occupation. 34: 1159-1163, 1
980.

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[Procedure Amendment] [Submission Date] June 10, 1994 [Procedure Amendment 1] [Amendment Document Name] Drawing [Amendment Item Name] All Drawings [Amendment Method] Change [Amendment Content] [Figure 1] [Figure 3] [Fig. 2] [Figure 4] [Figure 5] [Figure 6] [Figure 7] [Figure 8]

Claims (1)

[Claims for utility model registration] [Claim 1] A jelly-like disinfectant containing carbon fiber (1), a silver wire A (2) and an adhesive tape (3), wherein the silver wire A is a non-adhesive tape. Adhesive surface (4) with conductor A
An electrode having a structure connected to (5). 2. Inside the catheter wall for blood vessel placement after fixing the silver wire B (7) around the catheter (6) for blood vessel placement so that the catheter is slightly tightened and is continuously wound without a gap. An electrode having a structure in which the silver wire (8) is guided to the catheter tail for blood vessel placement (9). 3. A silver wire C (12) is wound around the catheter (11) for continuous portable peritoneal perfusion (CAPD) so that the first layer is a little tight and the catheter is continuously wrapped without leaving a gap. (13) After twisting and fixing both ends (14), the second and third layers are slightly roughened and wound so that a space is maintained between the silver wires (15), A ring (16) around which the needle thread passes
After making several silver wires by twisting the silver wire, one end of the silver wire is guided to the CAPD catheter tail (18) as the silver wire (17) in the CAPD catheter wall.