JPH07123928A - Agent for preventing poultry disease and feed for poultry - Google Patents
Agent for preventing poultry disease and feed for poultryInfo
- Publication number
- JPH07123928A JPH07123928A JP5302193A JP30219393A JPH07123928A JP H07123928 A JPH07123928 A JP H07123928A JP 5302193 A JP5302193 A JP 5302193A JP 30219393 A JP30219393 A JP 30219393A JP H07123928 A JPH07123928 A JP H07123928A
- Authority
- JP
- Japan
- Prior art keywords
- feed
- coenzyme
- poultry
- ascites
- experimental
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
【０００１】[0001]
【産業上の利用分野】本発明は家禽疾病予防剤および家
禽用飼料、さらに詳しくはブロイラ−鶏に多発する腹水
症ならびに突然死症候群を予防可能な家禽疾病予防剤お
よび同家禽疾病予防剤の有効成分を添加して成る家禽用
飼料に関するものである。FIELD OF THE INVENTION The present invention relates to a preventive agent for poultry diseases and a feed for poultry, and more particularly, a preventive agent for poultry diseases and a preventive agent for poultry diseases which can prevent ascites and sudden death syndrome which frequently occur in broiler chickens. The present invention relates to a poultry feed comprising the addition of ingredients.
【０００２】[0002]
【従来の技術】近年、ブロイラ−鶏の経済的飼育時に腹
水症ならびに突然死症候群が多発し、これらの疾病によ
るブロイラ−鶏の死亡率は時には４〜１０％もの高率に
達し、ブロイラ−鶏を飼育する農家、企業に重大な経済
的損失、打撃を与えている。2. Description of the Related Art Recently, ascites and sudden death syndrome frequently occur during economical breeding of broiler chickens, and the mortality rate of broiler chickens due to these diseases sometimes reaches as high as 4 to 10%. It causes serious economic loss and damage to the farmers and enterprises that breed.
【０００３】ブロイラ−鶏の腹水症ならびに突然死症候
群は、共に鶏の肺動脈高血圧症に起因する心臓肥大、特
に右心室肥大を顕著に呈する非感染性の疾病である。[0003] Broiler-chicken ascites and sudden death syndrome are both non-infectious diseases in which chicken hypertrophy, particularly right ventricular hypertrophy, is prominent due to pulmonary arterial hypertension in chickens.
【０００４】前者の罹患鶏は一様に腹部が膨満し、沈
鬱、チアノ−ゼ、下痢便排泄、歩行困難の症状を呈し、
心臓の周囲あるいは腹腔内に水腫性液の貯留を伴い、慢
性的な成長不良経過を辿り死亡に至る。後者の罹患鶏は
上体、特に頭、頚部から前胸部に充血、鬱血が顕著であ
り、顕著な右心房の拡張及び血液の鬱滞を認める。In the former affected chicken, the abdomen is uniformly bloated, and symptoms of depression, cyanosis, excretion of diarrhea and feces, and difficulty walking are exhibited.
With the accumulation of edematous fluid around the heart or in the abdominal cavity, a chronic poor growth process is followed leading to death. In the latter affected chickens, hyperemia and congestion in the upper body, especially from the head and neck to the precordial region are prominent, and marked dilation of the right atrium and blood congestion are observed.
【０００５】また、全身諸臓器に組織学的な高度の鬱血
性変化を認める。本症候群は突然に発症し死亡に至る。
「鶏病研報 21 巻3 号,129〜136 頁（1985) ；同誌 16
巻2号,43 〜48頁(1980) 参照」Further, histologically high degree of congestive changes are observed in various organs throughout the body. This syndrome suddenly develops and results in death.
"Chick Disease Research Report, Vol. 21, No. 3, pp. 129-136 (1985); ibid. 16
Volume 2, pp. 43-48 (1980) "
【０００６】これらの両疾病の原因あるいは関係につい
ては、未だ明確な知見は得られていないが、何れも酸素
要求量の増大する飼育環境下で多発することが認められ
ている。[0006] The cause or relationship between these two diseases has not been clarified yet, but it has been recognized that they frequently occur in a breeding environment where oxygen demand increases.
【０００７】例えば高エネルギ−飼料或はペレット飼料
の給与による飼育による多発が認められ、腹水症は最初
にメキシコの高地で発生、報告されたように、これらの
飼育条件に加えて寒冷地あるいは高地での飼育などの飼
育環境条件が加わると発症率はさらに高まる。また、季
節的要因も指摘されている。[0007] For example, as a result of occurrence of ascites in the highlands of Mexico at the beginning, ascites occurred frequently in the high-energy feeds or pellet feeds. Incidence rates will increase further when breeding environmental conditions such as breeding in Japan are added. In addition, seasonal factors have been pointed out.
【０００８】ブロイラ−鶏の飼育は、通常、初生雛を８
週間飼育し、この間に飼料効率を最大ならしめるべく飼
育管理を行うが、腹水症は３〜８週令雛に、また、突然
死症候群は２〜８週令雛に多発する傾向が認められる。
さらに、早期に成長の速い雛程、発症率の高い傾向も認
められる。Broiler-chicken are usually bred with eight newborn chicks.
The animals are bred for a week, and breeding management is performed to maximize the feed efficiency during this period, but ascites tends to occur frequently in 3-8 week old chicks and sudden death syndrome in 2-8 week old chicks.
In addition, there is a tendency that the faster the chicks grow, the higher the incidence.
【０００９】腹水症ならびに突然死症候群の発生は、単
に雛の死亡による鶏肉生産量の低下ばかりではなく、前
者を罹患し生存した雛にあっても肉質不良のため、ある
いは群を構成する個体の成長が不均一との理由から、そ
の経済的価値は極めて低いものとなる。The occurrence of ascites and sudden death syndrome is not only due to a decrease in chicken production due to the death of the chicks, but also because of poor meat quality even in the surviving chicks affected by the former, or in the individuals constituting the group. Its economic value is extremely low because of uneven growth.
【００１０】従来、腹水症ならびに突然死症候群の予防
対策としては、種々の方法が模索されているが、これら
の疾病が非感染性の疾病であることもあって、未だに有
効な対策は見出されていない。Conventionally, various methods have been sought as a preventive measure for ascites and sudden death syndrome. However, since these diseases are non-infectious diseases, effective measures are still found. It has not been.
【００１１】また、これらの疾病の予防に有効な薬剤な
いし飼料添加物に関しても、種々の検討がなされてきた
が、未だ、腹水症並びに突然死症候群の発生を予防する
有効な物質は見出されていない。Further, various investigations have been made on drugs or feed additives effective for preventing these diseases, but an effective substance for preventing the occurrence of ascites and sudden death syndrome has been found. Not not.
【００１２】かかる事情の下で、ブロイラ−鶏を飼育す
る農家、企業では、やむなく、エネルギ−含有量を低下
した飼料を給与し雛の成長を制限することにより、飼料
効率を抑止し経済効率を犠牲にする対策を採用してい
る。Under these circumstances, farmers and companies that raise broiler chickens are compelled to feed the feed having a reduced energy content to limit the growth of the chicks, thereby suppressing the feed efficiency and increasing the economic efficiency. Employs sacrificial measures.
【００１３】[0013]
【発明が解決しようとする課題】本発明では以上の事情
に鑑み、ブロイラ−鶏の腹水症ならびに突然死症候群の
発生を予防するために有効な物質乃至方法を見出すこと
を目的とする。In view of the above circumstances, it is an object of the present invention to find a substance or method effective for preventing the occurrence of ascites and sudden death syndrome in broiler chickens.
【００１４】[0014]
【課題を解決するための手段】本発明者は上記の課題を
解決すべく、ブロイラ−鶏の腹水症ならびに突然死症候
群の発生を予防するために有効な物質乃至方法に関し、
鋭意、広範囲に亙り検索、検討の結果、補酵素Ｑ9 また
は補酵素Ｑ10が卓効を示す物質であることを発見した。In order to solve the above problems, the present inventor relates to substances and methods effective for preventing the occurrence of ascites and sudden death syndrome in broiler chickens,
As a result of diligent and extensive searches and studies, it was discovered that coenzyme Q 9 or coenzyme Q 10 is a substance exhibiting excellent effects.
【００１５】本発明はこの発見に基づき完成されたもの
であって、すなわち、 （発明１） 補酵素Ｑ9 または補酵素Ｑ10より成る家禽
疾病予防剤、および （発明２） 補酵素Ｑ9 または補酵素Ｑ10を添加して成
る家禽用飼料、 である。The present invention has been completed based on this discovery, namely, (Invention 1) a poultry disease preventive agent comprising coenzyme Q 9 or coenzyme Q 10 , and (Invention 2) coenzyme Q 9 or A poultry feed comprising the addition of coenzyme Q 10 .
【００１６】本発明における補酵素Ｑ9 または補酵素Ｑ
10は補酵素Ｑ群、すなわち、ユビキノン類を構成する主
要因子であり、生体のミトコンドリア内の電子伝達系に
関与する脂溶性のベンゾキノン類物質であって、高等動
植物より微生物に至るすべての生物の呼吸鎖の脂溶性成
分として重要な生理的意義を有し、広く生物界に存在す
る物質である。「メルク・インデクス（Merck Index)
第11版、第9751項（1989);生物化学辞典 第２版、1376
頁左欄（1990) （株）東京化学同人刊 参照」Coenzyme Q 9 or Coenzyme Q in the present invention
10 is a coenzyme Q group, that is, a major factor that constitutes ubiquinones, is a fat-soluble benzoquinone substance involved in the electron transfer system in mitochondria of living organisms, and is a substance of all organisms from higher animals and plants to microorganisms. It is a substance that has important physiological significance as a fat-soluble component of the respiratory chain and is widely present in the living world. "Merck Index
Eleventh Edition, Item 9751 (1989); Dictionary of Biochemistry, Second Edition, 1376.
Page left column (1990) See Tokyo Kagaku Doujinshi ”
【００１７】また、その生理的活性に基づき各種の医薬
としての利用、用途も知られている。例えば、けいれん
の治療、予防剤（特公平01−33082 ）、膵機能亢進剤
（特公昭58−45403 、前立腺肥大症治療、予防剤（特公
昭63−20804)としての用途が知られている。Further, based on its physiological activity, its use and use as various medicines are known. For example, it is known to be used as a therapeutic / preventive agent for spasms (Japanese Patent Publication No. 01-33082), a pancreatic function enhancer (Japanese Patent Publication No. 58-45403), a prostatic hypertrophy treatment, and a preventive agent (Japanese Patent Publication No. 63-20804).
【００１８】然しながら、獣医薬或は飼料添加物として
は全く知られることが無かった。However, it was never known as a veterinary drug or a feed additive.
【００１９】本発明において使用される補酵素Ｑ9 また
は補酵素Ｑ10は既知の方法、すなわち、有機合成的方法
ならびに植物体からの抽出或は発酵法などの生物化学的
方法により取得される。なお、発酵法による微生物菌体
からの製造方法は、例えば特公昭56−15234,特公昭56−
42912 , 特開昭57−129695, 特公昭59ー33354 , 特公昭
61−17471 各明細書に記載されている。The coenzyme Q 9 or coenzyme Q 10 used in the present invention is obtained by a known method, that is, an organic synthetic method and a biochemical method such as extraction from a plant or fermentation. Incidentally, the method for producing from microbial cells by the fermentation method is, for example, Japanese Patent Publication No. 15234/56,
42912, JP-A-57-129695, JP-B-59-33354, JP-B
61-17471 Described in each specification.
【００２０】また、本発明において使用される補酵素Ｑ
9 または補酵素Ｑ10は純品である必要はなく、補酵素Ｑ
9 または補酵素Ｑ10以外の補酵素Ｑ群に属する他の因子
を含有していてもよい。さらに補酵素Ｑ9 または補酵素
Ｑ10を高濃度に濃縮含有する天然物抽出物、例えばコ−
ンオイル製造時に副生する不鹸化物区分、上記の発酵法
による微生物菌体からの製造方法で取得する微生物菌
体、同抽出物等も使用できる。なお、補酵素Ｑ9 または
補酵素Ｑ10は自然界に広範囲に分布し、例えば大豆油や
コ−ンオイルにも含有されているので、これらを本発明
の補酵素Ｑ9 または補酵素Ｑ10として使用することも考
えられるが、有効量を使用しようとすれば必然的に多量
のこれらの油脂を添加することとなり、例えば飼料成分
に添加した場合には、混合物が油泥状となってしまい、
栄養の均衡を保つ上から、また、取扱い上からも、飼料
として給与することが困難となる。The coenzyme Q used in the present invention
9 or coenzyme Q 10 need not be pure, but coenzyme Q
9 or other factors belonging to the coenzyme Q group other than coenzyme Q 10 may be contained. Furthermore, a natural product extract containing coenzyme Q 9 or coenzyme Q 10 at a high concentration, for example, co-enzyme
It is also possible to use the unsaponifiable matter category produced as a by-product during the production of coconut oil, the microbial cells obtained by the method for producing microbial cells by the fermentation method, the extract thereof, and the like. Since coenzyme Q 9 or coenzyme Q 10 is widely distributed in nature and is also contained in soybean oil and corn oil, these are used as coenzyme Q 9 or coenzyme Q 10 of the present invention. Although it is possible to do so, if it is attempted to use an effective amount, a large amount of these fats and oils will be inevitably added, and for example, when added to the feed ingredients, the mixture becomes an oil mud,
It is difficult to feed as a feed from the standpoint of maintaining nutritional balance and handling.
【００２１】本発明の１における家禽疾病予防剤にあっ
ては、種々の剤形を採用できる。例えば飼料添加物とし
てのプレミックス組成物、微粒被覆錠剤、飲料水添加用
乳剤等である。また、飼料成分中の油脂に、予め、補酵
素Ｑ9 または補酵素Ｑ10を溶解しておいてもよい。With respect to the poultry disease preventive agent of the first aspect of the present invention, various dosage forms can be adopted. For example, it is a premix composition as a feed additive, a finely coated tablet, an emulsion for adding drinking water and the like. Further, coenzyme Q 9 or coenzyme Q 10 may be dissolved in advance in the fats and oils in the feed ingredients.
【００２２】補酵素Ｑ9 または補酵素Ｑ10の供与量は、
雛の体重、週令、供与する飼料の種類、とくにエネルギ
−含量、飼育環境等によりその都度、選択、決定される
が、概括的には１日当たり体重１ｋｇにつき０．３〜１
５０ｍｇ、特に０．６〜１５ｍｇ程度が適当である。The dose of coenzyme Q 9 or coenzyme Q 10 is
It is selected and decided each time depending on the weight of the chicks, the age of the chicks, the type of feed to be fed, especially the energy content, the breeding environment, etc., but generally 0.3 to 1 per 1 kg of body weight per day
50 mg, particularly about 0.6 to 15 mg is suitable.
【００２３】従って、本発明の１における家禽疾病予防
剤にあっては、各種の濃度の予防剤を予め、調製してお
くと好都合である。Therefore, in the preventive agent for poultry diseases according to the first aspect of the present invention, it is advantageous to prepare preventive agents at various concentrations in advance.
【００２４】本発明の２における家禽用飼料は、本発明
の１の家禽疾病予防剤を飼料成分と均一に混合して成る
組成物である。補酵素Ｑ9 または補酵素Ｑ10の添加量乃
至添加濃度は、上記の各種の条件により選択、決定され
るが、概括的には飼料添加濃度として５〜１０００ｐｐ
ｍ、特に１０〜１００ｐｐｍ程度が適当である。The poultry feed of the second aspect of the present invention is a composition obtained by uniformly mixing the poultry disease preventive agent of the first aspect of the present invention with feed ingredients. The addition amount or addition concentration of coenzyme Q 9 or coenzyme Q 10 is selected and determined according to the various conditions described above, but generally, the feed addition concentration is 5 to 1000 pp.
m, especially about 10 to 100 ppm is suitable.
【００２５】なお、飼料中に存在する補酵素Ｑ9 または
補酵素Ｑ10あるいは飼料に添加した補酵素Ｑ9 または補
酵素Ｑ10は、試料をメタノ−ル抽出、ヘキサン転溶後、
フロリジル・カラムクロマトグラフ法により分別した区
分について、メタノ−ル／エタノ−ル／過塩素酸を移動
相とする高速液体クロマトグラフ法により分析、測定し
た。It should be noted, coenzyme Q 9 or coenzyme Q 10 was added to the coenzyme Q 9 or coenzyme Q 10 and feed present in the feed, methanol Samples - Le extraction, hexane rolling溶後,
The sections separated by Florisil column chromatography were analyzed and measured by high performance liquid chromatography using methanol / ethanol / perchloric acid as a mobile phase.
【００２６】[0026]
【作用】本発明においては、補酵素Ｑ9 または補酵素Ｑ
10をブロイラ−鶏に供与することにより腹水症ならびに
突然死症候群の発生を顕著に予防することでき、経済的
に有利、かつ、安全にブロイラ−鶏の生産を実施し得
る。In the present invention, coenzyme Q 9 or coenzyme Q
By supplying 10 to broiler chickens, the occurrence of ascites and sudden death syndrome can be markedly prevented, and the broiler chickens can be produced economically and safely.
【００２７】[0027]
（実施例１） 表１に示す組成のブロイラ−鶏用基本飼
料Ａを調製した。この基本飼料Ａに体重１ｋｇ、１日当
たり５ｍｇになるように補酵素Ｑ10を添加して実験飼料
Ｂを調製した。添加は補酵素Ｑ10を基本飼料成分中の油
脂に溶解し、該油脂を他の成分と均一に混合する方法に
よった。４０日令のブロイラ−雄雛、各群８５羽を基本
飼料Ａあるいは実験飼料Ｂで飼育した。飼育はケ−ジの
床面を板張りにし、オガクズを敷いたケ−ジ内で行い、
飼料及び給水は自由摂取とした。４０〜４９日令間は５
℃一定の寒冷感作環境下に、５０〜５６日令間は２０℃
の環境下に飼育した。両飼料による飼育での腹水症の発
生率を表２に示す。実験飼料で飼育した雛の腹水症の発
生は皆無であった。(Example 1) A broiler-chicken basic feed A having the composition shown in Table 1 was prepared. Experimental feed B was prepared by adding coenzyme Q 10 to the basic feed A such that the body weight was 1 kg and the daily dose was 5 mg. The addition was carried out by dissolving coenzyme Q 10 in the fats and oils in the basic feed ingredients and uniformly mixing the fats and oils with other ingredients. Forty-four-day-old broiler-male chicks, 85 birds in each group, were bred with the basic diet A or the experimental diet B. Breeding is done in a cage with a wooden floor and the sawdust lined,
Feed and water were freely available. 5 between 40-49 days
20 ° C for 50-56 days under a constant cold sensitization environment
It was bred under the environment. Table 2 shows the incidence of ascites in breeding with both feeds. No ascites occurred in the chicks fed the experimental diet.
【００２８】[0028]
【表１】 [Table 1]
【００２９】[0029]
【表２】 [Table 2]
【００３０】（実施例２） 表３および表１に示す組成
のブロイラ−鶏用基本飼料Ｃおよび基本飼料Ａを調製し
た。この基本飼料Ｃおよび基本飼料Ａに飼料濃度が３０
ｐｐｍ或いは５０ｐｐｍになるように補酵素Ｑ10を添加
して実験飼料Ｄ、実験飼料Ｅならびに実験飼料Ｆ、実験
飼料Ｇを調製した。添加は実施例１と同様に行った。１
４日令のブロイラ−雄雛、各群４８羽を２１日令までは
基本飼料Ｃあるいは実験飼料Ｄまたは実験飼料Ｅで飼育
した。２２〜５６日令間は基本飼料Ｃ飼育区には基本飼
料Ｃに換えて実施例１の基本飼料Ａを、実験飼料Ｄ飼育
区または実験飼料Ｅ飼育区には実験飼料Ｆまたは実験飼
料Ｇをそれぞれ給与して飼育した。飼育は平飼いの小ペ
ン内で行い、飼料および給水は自由摂取とした。１４〜
２１日令間は０〜５℃の寒冷環境に暴露し、２２〜５６
日令間は適温飼育環境下で飼育した。Example 2 Broiler-chicken basic feed C and basic feed A having the compositions shown in Tables 3 and 1 were prepared. This basic feed C and basic feed A have a feed concentration of 30.
Experimental feed D, experimental feed E, experimental feed F, and experimental feed G were prepared by adding coenzyme Q 10 so as to have a ppm or 50 ppm. The addition was performed in the same manner as in Example 1. 1
Up to 21 days old, 4-day-old broiler-male chicks in each group were bred with the basic diet C, the experimental diet D, or the experimental diet E. During the period from 22 to 56 days, the basic feed C was replaced with the basic feed C in Example 1, and the experimental feed D or the experimental feed E was fed with the experimental feed F or the experimental feed G. Each was fed and raised. The animals were raised in small flat pens, and the feed and water were freely ingested. 14 ~
During the 21-day period, exposed to a cold environment of 0 to 5 ° C, 22 to 56
During the day, the animals were kept in a suitable temperature breeding environment.
【００３１】基本飼料Ｃ、Ａ飼育区ならびに実験飼料
Ｄ、Ｆ飼育区または実験飼料Ｆ、Ｇ飼育区における腹水
症または突然死症候群の発生率を表４に示す。実験飼料
Ｄ、Ｆ飼育区または実験飼料Ｅ、Ｇ飼育区における腹水
症または突然死症候群の発生率は基本飼料Ｃ、Ａ飼育区
のそれらの発生率に比較して顕著、かつ、有意義に低い
ことを認めた。Table 4 shows the incidences of ascites or sudden death syndrome in the basic diets C and A breeding groups and the experimental diets D and F breeding groups or the experimental diets F and G breeding groups. The incidence of ascites or sudden death syndrome in the experimental diets D, F or the experimental diets E, G is significant and significantly lower than those in the basic diets C, A. Admitted.
【００３２】[0032]
【表３】 [Table 3]
【００３３】[0033]
【表４】 [Table 4]
【００３４】（実施例３） 実施例２の表３に示す組成
と同一のブロイラ−鶏用基本飼料Ｈを調製した。この基
本飼料Ｈに体重１ｋｇ、１日当たり５ｍｇまたは１０ｍ
ｇになるように補酵素Ｑ9 を添加して実験飼料Ｉまたは
実験飼料Ｊを調製した。添加は実施例１と同様に行っ
た。飼育は平飼いの小ペン内で行い、飼料および給水は
自由摂取とした。ブロイラ−初生雄雛、各群１２０羽を
基本飼料Ｈあるいは実験飼料Ｉまたは実験飼料Ｊでに飼
育した。各飼育群とも１３日令迄は適温飼育環境下に、
１４〜２１日令間は５℃一定の寒冷感作環境下に、ま
た、２２〜５６日令間は２０℃の環境下に飼育した。Example 3 A broiler-chicken basic feed H having the same composition as shown in Table 3 of Example 2 was prepared. Body weight 1kg, 5mg or 10m per day on this basic feed H
Experimental feed I or experimental feed J was prepared by adding coenzyme Q 9 so that the amount became g. The addition was performed in the same manner as in Example 1. The animals were raised in small flat pens, and the feed and water were freely ingested. Broiler-primary male chicks, 120 birds in each group, were fed with the basic feed H or the experimental feed I or the experimental feed J. For each breeding group, keep it in a proper temperature breeding environment until the age of 13 days,
The animals were bred under the constant cold sensitization environment of 5 ° C for 14 to 21 days, and under the environment of 20 ° C for 22 to 56 days.
【００３５】基本飼料Ｈ飼育区ならびに実験飼料Ｉ飼育
区または実験飼料Ｊ飼育区における腹水症又は突然死症
候群の発生率を表５に示す。 実験飼料Ｉ飼育区または
実験飼料Ｊ飼育区における腹水症または突然死症候群の
発生率は基本飼料Ｈ飼育区のそれらの発生率に比較して
顕著、かつ、有意義に低いことを認めた。Table 5 shows the incidence of ascites or sudden death syndrome in the basic feed H breeding group and the experimental feed I breeding group or the experimental feed J breeding group. It was confirmed that the incidence of ascites or sudden death syndrome in the experimental feed I breeding group or the experimental feed J breeding group was remarkable and significantly lower than those in the basic feed H breeding group.
【００３６】[0036]
【表５】 [Table 5]
【００３７】[0037]
【発明の効果】以上説明した通り、本発明においては、
補酵素Ｑ9 または補酵素Ｑ10をブロイラ−鶏に供与する
ことにより腹水症ならびに突然死症候群の発生を顕著に
予防することでき、経済的に有利、かつ、安全にブロイ
ラ−鶏の生産を実施し得るという効果がある。As described above, according to the present invention,
By providing co-enzyme Q 9 or co-enzyme Q 10 to broiler chickens, it is possible to significantly prevent the occurrence of ascites and sudden death syndrome, and economically and safely produce broiler chickens. There is an effect that can be done.
フロントページの続き (72)発明者 小沢 正明 栃木県黒磯市青木919 伊藤忠飼料株式会 社総合技術研究部内 (72)発明者 安達 宗之助 栃木県黒磯市青木919 伊藤忠飼料株式会 社総合技術研究部内(72) Inventor Masaaki Ozawa 919 Aoki Aoki, Kuroiso City, Tochigi Prefecture In the Technical Research Department, ITOCHU FOOD CO., LTD.
Claims (2)
禽疾病予防剤。1. A poultry disease preventive agent comprising coenzyme Q 9 or coenzyme Q 10 .
成る家禽用飼料。2. A poultry feed comprising coenzyme Q 9 or coenzyme Q 10 .
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5302193A JPH07123928A (en) | 1993-11-09 | 1993-11-09 | Agent for preventing poultry disease and feed for poultry |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5302193A JPH07123928A (en) | 1993-11-09 | 1993-11-09 | Agent for preventing poultry disease and feed for poultry |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH07123928A true JPH07123928A (en) | 1995-05-16 |
Family
ID=17906062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5302193A Pending JPH07123928A (en) | 1993-11-09 | 1993-11-09 | Agent for preventing poultry disease and feed for poultry |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH07123928A (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998001039A1 (en) * | 1996-07-08 | 1998-01-15 | Idemitsu Materials Co., Ltd. | Feed composition for poultry |
| WO1998051164A1 (en) * | 1997-05-14 | 1998-11-19 | Idemitsu Petrochemical Co., Ltd. | Feed composition for broilers and method for breeding broilers |
| US5977185A (en) * | 1998-08-11 | 1999-11-02 | Rta Associates, Inc. | Method for prevention and treatment of production disease of genetically improved livestock and poultry |
| WO2000056294A3 (en) * | 1999-03-23 | 2001-08-23 | Lonza Ag | Carnitine supplemented diet to prevent sudden death syndrome in broiler breeder type poultry |
| JPWO2003007928A1 (en) * | 2001-07-17 | 2004-11-04 | 出光興産株式会社 | Poultry ascites inhibitor |
| JP2007074937A (en) * | 2005-09-12 | 2007-03-29 | Marubeni Nisshin Feed Co Ltd | Coenzyme q10-enriched egg, method for producing the same, and blended feed for poultry |
| WO2014003069A1 (en) * | 2012-06-29 | 2014-01-03 | 株式会社カネカ | Crustacean feed |
| WO2016024344A1 (en) * | 2014-08-13 | 2016-02-18 | 日清ファルマ株式会社 | Livestock production method and livestock-growth promoting method |
-
1993
- 1993-11-09 JP JP5302193A patent/JPH07123928A/en active Pending
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998001039A1 (en) * | 1996-07-08 | 1998-01-15 | Idemitsu Materials Co., Ltd. | Feed composition for poultry |
| EP1304041A1 (en) * | 1996-07-08 | 2003-04-23 | Idemitsu Petrochemical Co., Ltd. | Feed composition for poultry |
| US6251442B1 (en) * | 1997-05-14 | 2001-06-26 | Idemitsu Petrochemical Co., Ltd. | Feed composition for broilers and method for breeding broilers |
| WO1998051164A1 (en) * | 1997-05-14 | 1998-11-19 | Idemitsu Petrochemical Co., Ltd. | Feed composition for broilers and method for breeding broilers |
| US5977185A (en) * | 1998-08-11 | 1999-11-02 | Rta Associates, Inc. | Method for prevention and treatment of production disease of genetically improved livestock and poultry |
| WO2000056294A3 (en) * | 1999-03-23 | 2001-08-23 | Lonza Ag | Carnitine supplemented diet to prevent sudden death syndrome in broiler breeder type poultry |
| JP2002539242A (en) * | 1999-03-23 | 2002-11-19 | ロンザ ア−ゲ− | Carnitine supplementation to prevent sudden death in broiler slaughter-type poultry |
| JP4965026B2 (en) * | 1999-03-23 | 2012-07-04 | ロンザ アーゲー | Carnitine supplemented diet to prevent sudden death in broiler breeder poultry |
| JPWO2003007928A1 (en) * | 2001-07-17 | 2004-11-04 | 出光興産株式会社 | Poultry ascites inhibitor |
| JP4503286B2 (en) * | 2001-07-17 | 2010-07-14 | 出光興産株式会社 | Ascites prevention agent for poultry |
| JP2007074937A (en) * | 2005-09-12 | 2007-03-29 | Marubeni Nisshin Feed Co Ltd | Coenzyme q10-enriched egg, method for producing the same, and blended feed for poultry |
| WO2014003069A1 (en) * | 2012-06-29 | 2014-01-03 | 株式会社カネカ | Crustacean feed |
| JPWO2014003069A1 (en) * | 2012-06-29 | 2016-06-02 | 株式会社カネカ | Crustacean feed |
| WO2016024344A1 (en) * | 2014-08-13 | 2016-02-18 | 日清ファルマ株式会社 | Livestock production method and livestock-growth promoting method |
| JPWO2016024344A1 (en) * | 2014-08-13 | 2017-05-18 | 日清ファルマ株式会社 | Method for producing livestock and method for promoting growth of livestock |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Dieumou et al. | Effects of ginger (Zingiber officinale) and garlic (Allium sativum) essential oils on growth performance and gut microbial population of broiler chickens | |
| Hertz | The quantitative relationship between stilbestrol response and dietary “folic acid” in the chick | |
| Hamodi et al. | Effect of coriander seed (Coriandrum sativum L.) as diet ingredient on broilers performance under high ambient temperature | |
| CN112206237A (en) | Anti-aging composition containing zinc taurate, preparation method and application thereof | |
| Deniz et al. | Effects of two supplemental dietary selenium sources (mineral and organic) on broiler performance and drip-loss | |
| CN105475230B (en) | A kind of method for improving above the average age for marriage animal reproduction power | |
| CN105475636A (en) | Water-soluble garlicin mixture, and preparation method and use thereof | |
| Aguilar et al. | Effect of copaiba essential oil on broiler chickens' performance | |
| CN104304679A (en) | Multivitamin C, E immune polysaccharide microemulsion preparation and preparation method and application of preparation | |
| JPH07123928A (en) | Agent for preventing poultry disease and feed for poultry | |
| EP0170538B1 (en) | Use of certain compounds in livestock food as growth promotants | |
| TW201221066A (en) | Lauric acid distillate for animal feed | |
| CN106721305A (en) | It is a kind of to improve compositions of additives of body condition or its production performance and preparation method thereof after Farrowing | |
| Kraybill et al. | CHAPTER XV IMPLICATIONS OF FUNGAL TOXICITY TO HUMAN HEALTH | |
| JP2002223708A (en) | Feed composition for broiler and method for rearing broiler | |
| CN102550831B (en) | Cinnamic acid improves the application in the product of growth of animals or poultry performance in preparation | |
| JPH09187229A (en) | Feed composition for poultry | |
| Hanssen et al. | Vitamin C deficiency in growing willow ptarmigan (Lagopus lagopus lagopus) | |
| Suloma et al. | Re-evaluation of the effect of daily and within-day mixed feeding schedules of varying dietary protein content on the growth performance of Nile tilapia fry using constant ingredient composition | |
| Marudhupandi et al. | Effect of lipid supplementation, using oil extracted from Nannochloropsis salina on growth indices and expression of gene associated lipid metabolism in clownfish, Amphiprion ocellaris | |
| JP2003088301A (en) | Methane generation-inhibiting composition and feed composition each for ruminant | |
| US5977185A (en) | Method for prevention and treatment of production disease of genetically improved livestock and poultry | |
| JPH06287136A (en) | Agent for preventing ascites of broiler and method for preventing ascites | |
| Straka et al. | Biological control of the toxic shrub juniper. | |
| Mahfudz et al. | Interactive effect of cage density and dietary black cumin level on productive efficiency in broiler chickens |