JPH0710731A - Water-in-oil emulsified cosmetic - Google Patents
Water-in-oil emulsified cosmeticInfo
- Publication number
- JPH0710731A JPH0710731A JP5157338A JP15733893A JPH0710731A JP H0710731 A JPH0710731 A JP H0710731A JP 5157338 A JP5157338 A JP 5157338A JP 15733893 A JP15733893 A JP 15733893A JP H0710731 A JPH0710731 A JP H0710731A
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- water
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Abstract
Description
【０００１】[0001]
【産業上の利用分野】本発明は油中水型（以下「Ｗ／Ｏ
型」ということがある）乳化化粧料に関し、更に詳しく
は優れた保湿性、感触及び保存安定性を示し、しかも皮
膚に対し低刺激性のＷ／Ｏ型乳化化粧料に関する。The present invention relates to a water-in-oil type (hereinafter referred to as "W / O").
The present invention relates to an emulsified cosmetic composition, and more specifically to a W / O emulsified cosmetic composition that exhibits excellent moisturizing properties, feel and storage stability, and is mild to the skin.
【０００２】[0002]
【従来の技術及び発明が解決しようとする課題】従来、
クリーム、乳液等の乳化化粧料には、乳化剤として非イ
オン性界面活性剤やアニオン性界面活性剤が使用されて
いるが、これらはいずれも、多かれ少なかれ、皮膚刺激
性を有するものである。一方、ワセリンとラノリンアル
コールとを用いて得られる「アブソープションベース」
と呼ばれるＷ／Ｏ型乳化化粧料は、皮膚刺激性は低減さ
れているものの、皮膚の毛穴を閉塞することにより保湿
効果を発揮させるものであるため、使用感が悪く、ま
た、その保湿効果も持続性に乏しいものであった。2. Description of the Related Art Conventionally, the problems to be solved by the invention
Nonionic surfactants and anionic surfactants are used as emulsifiers in emulsified cosmetics such as creams and milky lotions, all of which are more or less irritating to the skin. On the other hand, "absorption base" obtained by using vaseline and lanolin alcohol
The W / O type emulsified cosmetics called soybeans have reduced skin irritation, but since they exert a moisturizing effect by closing pores in the skin, they have a bad feeling in use and also have a moisturizing effect. It was poor in sustainability.
【０００３】上記問題点を解決するための試みとして、
例えばアミド誘導体とコレステロールとをベースとする
Ｗ／Ｏ型乳化化粧料が開示されている（特開昭６４−４
２３６号公報）。As an attempt to solve the above problems,
For example, a W / O type emulsified cosmetic based on an amide derivative and cholesterol has been disclosed (JP-A-64-4).
No. 236).
【０００４】しかし、上記化粧料も、感触、保存安定性
等の点で未だ満足のいくものではなかった。However, the above cosmetics have not been satisfactory in terms of feeling, storage stability and the like.
【０００５】そこで、保湿性及び皮膚に対する低刺激性
を維持しながら、のび、しっとり感等の感触が良好で、
かつ保存安定性にも優れる油中水型乳化化粧料の開発が
望まれていた。Therefore, while maintaining the moisturizing property and the low irritation to the skin, the feeling of spreading and moisturizing is good,
Further, it has been desired to develop a water-in-oil type emulsion cosmetic which is excellent in storage stability.
【０００６】[0006]
【課題を解決するための手段】本発明者らは、かかる実
情に鑑み鋭意検討した結果、特定のアミド誘導体及びス
テリン類のジカルボン酸モノエステルを特定割合で用い
るＷ／Ｏ型乳化化粧料が優れた保湿性、感触及び保存安
定性をもたらすものであり、しかも皮膚に対し刺激性を
ほとんど示さないことを見出し、本発明を完成するに至
った。Means for Solving the Problems As a result of intensive studies made by the present inventors in view of such circumstances, a W / O type emulsion cosmetic using a specific amide derivative and a dicarboxylic acid monoester of sterins in a specific ratio is excellent. The present invention has been completed based on the finding that it provides moisturizing properties, touch and storage stability, and exhibits almost no irritation to the skin.
【０００７】すなわち、本発明は、下記成分（Ａ）、
（Ｂ）、（Ｃ）及び（Ｄ）； （Ａ）次の一般式（１）That is, the present invention provides the following component (A),
(B), (C) and (D); (A) The following general formula (1)
【０００８】[0008]
【化３】 [Chemical 3]
【０００９】で表わされるアミド誘導体、 （Ｂ）次の一般式（２）An amide derivative represented by (B) the following general formula (2)
【００１０】[0010]
【化４】 [Chemical 4]
【００１１】で表わされる天然ステリン又はその水素添
加物のジカルボン酸モノエステルの一種又は二種以上、 （Ｃ）油性物質 １０〜７０重量％、 （Ｄ）水 １０〜８８重量％、 を含有し、かつ（Ａ）／（Ｂ）が重量比で０．０１〜１
０であって、更に親水性の界面活性剤を実質的に含有し
ないことを特徴とする油中水型乳化化粧料を提供するも
のである。One or more dicarboxylic acid monoesters of natural sterins or hydrogenated products thereof represented by: (C) 10 to 70% by weight of oily substance, (D) 10 to 88% by weight of water, and And (A) / (B) is 0.01-1 by weight ratio.
The present invention provides a water-in-oil type emulsion cosmetic, which is 0 and further does not substantially contain a hydrophilic surfactant.
【００１２】本発明は使用される成分（Ａ）のアミド誘
導体（１）の炭化水素基Ｒ1 は飽和でも不飽和のもので
もよく、その好ましい炭素数は１０〜１８である。ま
た、炭化水素基Ｒ2 は飽和でも不飽和のものでもよく、
その好ましい炭素数は９〜１７である。In the present invention, the hydrocarbon group R 1 of the amide derivative (1) of the component (A) used may be saturated or unsaturated, and the preferred carbon number is 10-18. The hydrocarbon group R 2 may be saturated or unsaturated,
The preferable carbon number is 9-17.
【００１３】成分（Ａ）の本発明組成物への配合量は、
良好な保湿性及び感触を得るため０．１〜３０重量％
（以下、「％」で示す）が好ましく、１〜１５％が特に
好ましい。The amount of component (A) to be added to the composition of the present invention is
0.1 to 30% by weight to obtain good moisturizing properties and feel
(Hereinafter, indicated by "%") is preferable, and 1 to 15% is particularly preferable.
【００１４】成分（Ａ）のアミド誘導体（１）は、例え
ば特開昭６２−２２８０４８号公報に記載の方法に従い
製造できる。The amide derivative (1) of the component (A) can be produced, for example, according to the method described in JP-A-62-228048.
【００１５】本発明に使用される成分（Ｂ）の天然ステ
リン又はその水素添加物のジカルボン酸モノエステル
（２）（以下、「ステリン誘導体」と呼ぶことがある）
の基Ｒ 4 としては、例えば直鎖又は分岐鎖の２−ヘキセ
ニル基、２−オクテニル基、２−デセニル基、２−ドデ
セニル基、２−テトラデセニル基、２−ヘキサデセニル
基、２−オクタデセニル基、２−エイコセニル基、ヘキ
シル基、オクチル基、デシル基、ドデシル基、テトラデ
シル基、ヘキサデシル基、オクタデシル基、エイコシル
基等が例示され、その中でも２−テトラデセニル基、２
−ヘキサデセニル基、２−オクタデセニル基、２−エイ
コセニル基、テトラデシル基、ヘキサデシル基、オクタ
デシル基、エイコシル基等が挙げられる。The natural starch of the component (B) used in the present invention
Dicarboxylic acid monoester of phosphorus or its hydrogenated product
(2) (hereinafter sometimes referred to as "sterin derivative")
Base R FourAre, for example, linear or branched 2-hexene
Nyl group, 2-octenyl group, 2-decenyl group, 2-dode
Cenyl group, 2-tetradecenyl group, 2-hexadecenyl group
Group, 2-octadecenyl group, 2-eicosenyl group, hex
Syl group, octyl group, decyl group, dodecyl group, tetrade
Syl group, hexadecyl group, octadecyl group, eicosyl
Groups and the like, among which, 2-tetradecenyl group, 2
-Hexadecenyl group, 2-octadecenyl group, 2-ei
Cocenyl group, tetradecyl group, hexadecyl group, octa
Examples thereof include a decyl group and an eicosyl group.
【００１６】基Ｒ5 は、天然ステリン又はその水素添加
物の水酸基プロトンを除く残基を示す。天然ステリンと
しては、コレステロール、スチグマステロール、シトス
テロール、チノステロール、エルゴステロール等が挙げ
られるが、これらのうち、コレステロールが好ましい。The group R 5 represents a residue excluding a hydroxyl group proton of natural sterin or a hydrogenated product thereof. Examples of natural sterins include cholesterol, stigmasterol, sitosterol, tinosterol, ergosterol and the like, and of these, cholesterol is preferable.
【００１７】成分（Ｂ）の天然ステリン又はその水素添
加物のジカルボン酸モノエステル（２）は、上記ステリ
ン類を、例えばアルケニルコハク酸無水物若しくはアル
キルコハク酸無水物と反応させ、必要に応じてアルカリ
性物質で中和することにより得られる。またＲ4 基、Ｒ
5 基に不飽和二重結合を持たないものについては、ステ
リン類とアルケニルコハク酸無水物若しくはアルキルコ
ハク酸無水物とを反応させた後、貴金属触媒などを用い
る通常の方法で水素添加することによっても得られる。The dicarboxylic acid monoester (2) of component (B) natural sterin or a hydrogenated product thereof is obtained by reacting the above sterins with, for example, an alkenylsuccinic anhydride or an alkylsuccinic anhydride, and if necessary. Obtained by neutralizing with an alkaline substance. R 4 group, R
For those having no unsaturated double bond in the 5 group, by reacting sterins with an alkenylsuccinic anhydride or an alkylsuccinic anhydride, hydrogenation is carried out by a usual method using a noble metal catalyst or the like. Can also be obtained.
【００１８】上記ステリン誘導体（２）のＲ3 が-(CH2)
p-である場合、ｐは２〜１０、好ましくは２〜５であ
る。R 3 of the sterin derivative (2) is — (CH 2 ).
When p −, p is 2-10, preferably 2-5.
【００１９】成分（Ｂ）の本発明組成物への配合量は、
０．１〜３０％が好ましく、更に１〜１５％が好まし
い。The amount of component (B) incorporated into the composition of the present invention is
0.1-30% is preferable and 1-15% is more preferable.
【００２０】上記成分（Ａ）と成分（Ｂ）とは、重量比
（成分（Ａ）／成分（Ｂ））で０．０１〜１０、好まし
くは０．１〜１．０の割合で本発明組成物に配合する。
成分（Ａ）と成分（Ｂ）とは、上記割合で混合されるこ
とにより安定な複合体を形成し、優れた乳化作用を示す
とともに顕著に向上した保湿作用をもたらす。The above component (A) and component (B) are used in the present invention in a weight ratio (component (A) / component (B)) of 0.01 to 10, preferably 0.1 to 1.0. Incorporate into the composition.
The component (A) and the component (B) are mixed in the above proportions to form a stable complex, exhibit an excellent emulsifying action, and bring about a significantly improved moisturizing action.
【００２１】本発明に使用される成分（Ｃ）の油性物質
としては、皮膚に対しての刺激がないものであれば特に
制限はなく、従来から化粧品や外用薬剤等の基剤として
利用されているものを用いることができる。具体的な成
分（Ｃ）の例としては、ワセリン、セレシン、固形パラ
フィン、マイクロクリスタリンワックス、流動パラフィ
ン、スクアラン等の炭化水素：オリーブ油、ホホバ油、
ラノリン、ヒマシ油、カカオ油、マカデミアナッツ油、
ミンク油等の天然動植物油脂：ミリスチン酸オクチルド
デシル、イソプロピルミリステート、イソプロピルパル
ミテート等の合成エステル油等：その他シリコーン誘導
体、高級脂肪酸、高級アルコール等が挙げられる。The oily substance of the component (C) used in the present invention is not particularly limited as long as it does not irritate the skin, and it has been conventionally used as a base for cosmetics and external medicines. It can be used. Specific examples of the component (C) include hydrocarbons such as petrolatum, ceresin, solid paraffin, microcrystalline wax, liquid paraffin and squalane: olive oil, jojoba oil,
Lanolin, castor oil, cacao oil, macadamia nut oil,
Natural animal and vegetable oils and fats such as mink oil: synthetic ester oils such as octyldodecyl myristate, isopropyl myristate, isopropyl palmitate and the like: other silicone derivatives, higher fatty acids, higher alcohols and the like.
【００２２】成分（Ｃ）の本発明組成物への配合量は、
１０〜７０％、好ましくは２０〜５０％である。The amount of component (C) incorporated into the composition of the present invention is
It is 10 to 70%, preferably 20 to 50%.
【００２３】成分（Ｄ）の水の本発明化粧料への配合量
は、１０〜８８％、好ましくは３０〜８５％である。The content of the component (D) in the cosmetic of the present invention is 10 to 88%, preferably 30 to 85%.
【００２４】本発明のＷ／Ｏ型乳化化粧料は、前記成分
（Ａ）〜（Ｄ）を必須成分としてそれぞれ特定量含有す
るものであり、かつ親水性の界面活性剤を実質的に含有
しないものである。The W / O type emulsified cosmetic composition of the present invention contains the above components (A) to (D) as essential components in specific amounts, and does not substantially contain a hydrophilic surfactant. It is a thing.
【００２５】本発明のＷ／Ｏ型乳化化粧料には、上記成
分（Ａ）〜成分（Ｄ）の必須成分のほか、本発明の効果
を損なわない範囲で、必要に応じてグリセリン、ソルビ
トール、マルチトール、プロピレングリコール、ジプロ
ピレングリコール、１，３−ブチレングリコール、ピロ
リドンカルボン酸ナトリウム、ポリオキシエチレンメチ
ルグルコシド、ポリオキシプロピレンメチルグルコシ
ド、グルコース等の調湿剤：アミノ酸：グリチルリチ
ン、アズレン、アラントイン等の消炎剤、パラベン等の
殺菌防腐剤、ビタミンＡ、Ｄ、Ｅ及びその誘導体、紫外
線吸収剤、その他色素、顔料、香料等を配合することが
できる。In the W / O type emulsion cosmetic of the present invention, in addition to the essential components of the above components (A) to (D), if necessary, glycerin, sorbitol, and Humidity regulators such as maltitol, propylene glycol, dipropylene glycol, 1,3-butylene glycol, sodium pyrrolidonecarboxylate, polyoxyethylene methyl glucoside, polyoxypropylene methyl glucoside, glucose: amino acids: glycyrrhizin, azulene, allantoin, etc. Anti-inflammatory agents, bactericidal preservatives such as parabens, vitamins A, D, E and derivatives thereof, ultraviolet absorbers, other dyes, pigments, fragrances and the like can be added.
【００２６】本発明のＷ／Ｏ型乳化化粧料は、例えば次
のようにして調製される。まず成分（Ａ）と成分（Ｂ）
を８０〜１８０℃で加熱混合する。次いで成分（Ｃ）を
添加し、温度を６０〜９０℃とする。更にこの混合物を
攪拌しながら６０〜９０℃に保温した成分（Ｄ）を少量
づつ添加する。この組成物を攪拌しつつ冷却することに
より、目的のＷ／Ｏ型乳化化粧料を得る。The W / O type emulsion cosmetic of the present invention is prepared, for example, as follows. First, component (A) and component (B)
Are mixed by heating at 80 to 180 ° C. Then, the component (C) is added to bring the temperature to 60 to 90 ° C. Furthermore, the component (D) kept at 60 to 90 ° C. is added little by little while stirring this mixture. The desired W / O type emulsified cosmetic composition is obtained by cooling this composition with stirring.
【００２７】[0027]
【発明の効果】本発明の油中水型乳化化粧料は、優れた
保湿性、感触及び保存安定性をもたらすものであるとと
もに、皮膚に対する刺激性をほとんど示さないものであ
る。The water-in-oil type emulsion cosmetic of the present invention provides excellent moisturizing properties, touch and storage stability, and exhibits almost no irritation to the skin.
【００２８】[0028]
【実施例】以下に本発明を実施例により具体的に説明す
るが本発明はこれらに限定されるものではない。EXAMPLES The present invention will be described below in greater detail by giving Examples, but the present invention is not limited thereto.
【００２９】製造例１（成分（Ｂ）の製造） 温度計と攪拌機を備えた、容量５００mlの反応容器に、
コレステロール１０９．１ｇ（２８２mmol）を仕込み、
窒素ガス通気下、油浴中で１６０℃に加熱し、コレステ
ロールを溶解させた。次いでｎ−ヘキサデセニルコハク
酸無水物９０．９ｇ（２８２mmol）を加えて、１６０℃
で攪拌しながら１０分間加熱した後、１３０℃まで冷却
し、更に１時間攪拌した。反応物を室温に冷却し、淡黄
色で粘稠なペースト状の物質２００ｇを得た。これをシ
リカゲルを使用したカラムクロマトグラフィー（移動
相；ヘキサン／酢酸エチル＝４／１）により精製し、無
色、半透明なペースト状のｎ−ヘキサデセニルコハク酸
コレステリルモノエステル〔化合物（Ｂ−１）〕１７
８．４ｇ（収率８９．２％）を得た。得られた化合物
（Ｂ−１）の酸価、ケン化価及び水酸基価の実測値及び
理論値を表１に示す。Production Example 1 (Production of Component (B)) In a reaction vessel with a thermometer and a stirrer and having a capacity of 500 ml,
Charge 109.1 g (282 mmol) of cholesterol,
The mixture was heated to 160 ° C. in an oil bath under a nitrogen gas atmosphere to dissolve cholesterol. Next, 90.9 g (282 mmol) of n-hexadecenylsuccinic anhydride was added, and the temperature was increased to 160 ° C.
After heating for 10 minutes while stirring with, the mixture was cooled to 130 ° C. and further stirred for 1 hour. The reaction was cooled to room temperature to yield 200 g of a pale yellow viscous pasty material. This was purified by column chromatography using silica gel (mobile phase; hexane / ethyl acetate = 4/1), and a colorless, translucent paste-like n-hexadecenylsuccinic acid cholesteryl monoester [compound (B- 1)] 17
8.4 g (yield 89.2%) was obtained. Table 1 shows measured and theoretical values of the acid value, saponification value and hydroxyl value of the obtained compound (B-1).
【００３０】[0030]
【表１】 [Table 1]
【００３１】得られた化合物（Ｂ−１）のＩＲスペクト
ル及び1Ｈ−ＮＭＲスペクトルは以下のとおりであり、
元素分析値は表２に示すとおりである。更に化学式を下
記に示す。The IR spectrum and 1 H-NMR spectrum of the obtained compound (B-1) are as follows,
The elemental analysis values are shown in Table 2. The chemical formula is shown below.
【００３２】ＩＲスペクトル（液膜法） 2960, 2926, 2854, 1740(C=0 伸縮), 1710(C=0伸縮), 1
470, 1380cm-1 1 Ｈ−ＮＭＲスペクトル（δ,ppm）CDCl3中 ａ；０．７０（ｓ，３Ｈ） ｂ；０．７５〜２．４０（ｍ，５５Ｈ） ｃ；０．８０（ｄ，６Ｈ） ｄ；０．９３（ｄ，３Ｈ） ｅ；１．００（ｓ，３Ｈ） ｆ；２．４０〜３．０（ｍ，３Ｈ） ｇ；４．６５（ｍ，１Ｈ） ｈ；５．３５（ｍ，３Ｈ） ｉ；１１．５（ｍ，１Ｈ） ａ〜ｉは下記化学式中のそれぞれのプロトンに対応す
る。IR spectrum (liquid film method) 2960, 2926, 2854, 1740 (C = 0 stretching), 1710 (C = 0 stretching), 1
470, 1380cm -1 1 H-NMR spectrum (δ, ppm) in CDCl 3 a; 0.70 (s, 3H) b; 0.75~2.40 (m, 55H) c; 0.80 (d, 6H) d; 0.93 (d, 3H) e; 1.00 (s, 3H) f; 2.40 to 3.0 (m, 3H) g; 4.65 (m, 1H) h; 35 (m, 3H) i; 11.5 (m, 1H) a to i correspond to the respective protons in the following chemical formula.
【００３３】[0033]
【表２】 [Table 2]
【００３４】[0034]
【化５】 [Chemical 5]
【００３５】製造例２（成分（Ｂ）の製造） 製造例１と同様にして、ｎ−オクタデセニルコハク酸コ
レステリルモノエステル〔化合物（Ｂ−２）〕を製造し
た。得られた化合物（Ｂ−２）の酸価、ケン化価及び水
酸基価の実測値及び理論値を表３に示す。Production Example 2 (Production of Component (B)) In the same manner as in Production Example 1, n-octadecenylsuccinic acid cholesteryl monoester [compound (B-2)] was produced. Table 3 shows measured and theoretical values of the acid value, saponification value and hydroxyl value of the obtained compound (B-2).
【００３６】[0036]
【表３】 [Table 3]
【００３７】得られた化合物（Ｂ−２）のＩＲスペクト
ル及び1Ｈ−ＮＭＲスペクトルは以下のとおりであり、
元素分析値は表４に示すとおりである。更に化学式を下
記に示す。The IR spectrum and 1 H-NMR spectrum of the obtained compound (B-2) are as follows:
The elemental analysis values are shown in Table 4. The chemical formula is shown below.
【００３８】ＩＲスペクトル（液膜法） 2960, 2925, 2850, 1742(C=0 伸縮), 1713(C=0 伸縮),
1460, 1380cm-1 1 Ｈ−ＮＭＲスペクトル（δ,ppm）CDCl3中 ａ；０．６８（ｓ，３Ｈ） ｂ；０．７５〜２．４０（ｍ，５９Ｈ） ｃ；０．８０（ｄ，６Ｈ） ｄ；０．９５（ｄ，３Ｈ） ｅ；１．００（ｓ，３Ｈ） ｆ；２．４０〜３．０（ｍ，３Ｈ） ｇ；４．６０（ｍ，１Ｈ） ｈ；５．４０（ｍ，３Ｈ） ｉ；１１．３（ｍ，１Ｈ） ａ〜ｉは下記化学式中のそれぞれのプロトンに対応す
る。IR spectrum (liquid film method) 2960, 2925, 2850, 1742 (C = 0 stretching), 1713 (C = 0 stretching),
1460, 1380cm -1 1 H-NMR spectrum (δ, ppm) in CDCl 3 a; 0.68 (s, 3H) b; 0.75~2.40 (m, 59H) c; 0.80 (d, 6H) d; 0.95 (d, 3H) e; 1.00 (s, 3H) f; 2.40 to 3.0 (m, 3H) g; 4.60 (m, 1H) h; 40 (m, 3H) i; 11.3 (m, 1H) a to i correspond to respective protons in the following chemical formula.
【００３９】[0039]
【表４】 [Table 4]
【００４０】[0040]
【化６】 [Chemical 6]
【００４１】実施例１及び比較例１ 表５に組成を示すクリームを下記製造法により得た。 （製造法）油相成分（イ）と（ロ）若しくは（ロ′）を
８０℃に加熱融解し、混合した後、油相を得る。油相成
分（ハ）〜（ヘ）及び前記油相を混合し、加熱融解して
８０℃に保つ。一方、水相成分（ト）〜（チ）を８０℃
に加熱融解、混合したものを油相に徐々に添加し２０℃
まで徐冷しながら攪拌し、クリームを得た。得られたそ
れぞれのクリームについて、保湿持続効果及び保存安定
性を下記試験方法により調べた。結果を併せて表５に示
す。Example 1 and Comparative Example 1 A cream having the composition shown in Table 5 was obtained by the following production method. (Production method) The oil phase components (a) and (b) or (b ') are heated and melted at 80 ° C and mixed to obtain an oil phase. The oil phase components (c) to (f) and the oil phase are mixed, heated and melted and kept at 80 ° C. On the other hand, the water phase components (G) to (H) are added
Add to the oil phase by heating, melting and mixing at 20 ℃
The mixture was stirred while being slowly cooled to obtain a cream. With respect to each of the obtained creams, the moisturizing retention effect and storage stability were examined by the following test methods. The results are also shown in Table 5.
【００４２】（保湿持続効果）前記製造法で得られたク
リームの一定量をパネリストの前腕内側部に塗布し、３
時間静置した後、湯洗し、温度２０℃、湿度４０％の恒
温恒湿室に入り、３０分後に角質層中の水分含有量を比
較するためインピーダンスメーター（ＩＢＳ社製）で皮
膚のインピーダンスを測定した。保湿持続効果は、該イ
ンピーダンスメーターの平均値で示した。値が大きいほ
ど良好な保湿効果を示す。 （保存安定性）前記製造法で得られたクリームを温度４
０℃、湿度７５％で１カ月保存し、その後目視で分離の
様子を観察し、次の基準で評価した。 （評価基準） ○：油の分離及び結晶の析出なし。 ×：結晶の析出及び油の分離あり。(Permanent moisturizing effect) A fixed amount of the cream obtained by the above-mentioned production method was applied to the inner side of the forearm of a panelist, and 3
After standing for a while, wash in hot water, enter a constant temperature and humidity room at a temperature of 20 ° C and a humidity of 40%, and after 30 minutes, compare the impedance of the skin with an impedance meter (manufactured by IBS) to compare the water content in the stratum corneum. Was measured. The moisturizing effect was shown by the average value of the impedance meter. The larger the value, the better the moisturizing effect. (Storage stability) The cream obtained by the above-mentioned production method was stored at a temperature of 4
The sample was stored at 0 ° C. and a humidity of 75% for one month, and then the state of separation was visually observed and evaluated according to the following criteria. (Evaluation Criteria) O: No separation of oil and precipitation of crystals. X: Crystal precipitation and oil separation occurred.
【００４３】[0043]
【表５】 [Table 5]
【００４４】上記結果から、本発明化粧料は安定性がよ
く、高い保湿持続効果を併せもつことがわかる。From the above results, it can be seen that the cosmetic composition of the present invention has good stability and a high moisturizing effect.
【００４５】実施例２及び比較例２〜３ 表６に組成を示すクリームを実施例１と同様に調製し
た。得られたそれぞれのクリームについて下記方法によ
り皮膚刺激性試験を行った。Example 2 and Comparative Examples 2-3 A cream having the composition shown in Table 6 was prepared in the same manner as in Example 1. A skin irritation test was performed on each of the obtained creams by the following method.
【００４６】（試験方法）被験者１０名の上腕部に上記
方法で得た各クリームを塗布し、４８時間閉鎖塗布試験
を行い、以下の評価基準によって評点を求めた。次いで
下記計算式から刺激指数を算出した。結果を併せて表６
に示す。 （評価基準） ０：反応は認められない。 １：微かな紅斑を認める。 ２：明瞭な紅斑を認める。 ３：紅斑と浮腫を認める。 ４：紅斑と浮腫及び水泡の壊死或いは痂皮を認める。(Test Method) Each subject's upper arm was coated with each cream obtained by the above method, a closed coating test was conducted for 48 hours, and a score was obtained according to the following evaluation criteria. Then, the stimulation index was calculated from the following calculation formula. Table 6 together with the results
Shown in. (Evaluation criteria) 0: No reaction is observed. 1: A slight erythema is observed. 2: Clear erythema is observed. 3: Erythema and edema are observed. 4: Erythema and edema, necrosis of blisters or scabs are observed.
【００４７】[0047]
【数１】 [Equation 1]
【００４８】[0048]
【表６】 [Table 6]
【００４９】上記結果から、本発明化粧料は、皮膚刺激
性が著しく低減されていることがわかる。From the above results, it can be seen that the cosmetic of the present invention has remarkably reduced skin irritation.
【００５０】実施例３及び比較例４〜５ 表７に組成を示すクリームを実施例１と同様に調製し
た。得られたそれぞれのクリームについて下記評価項目
について実用評価を行った。Example 3 and Comparative Examples 4-5 Creams having the compositions shown in Table 7 were prepared in the same manner as in Example 1. Practical evaluation was performed on the following evaluation items for each of the obtained creams.
【００５１】（試験方法）専門パネリスト１０名が、前
記製造法で調製したクリームを実際に使用し、実用評価
を行った。評価項目は、指どれのよさ、のび、肌へのな
じみ、しっとり感の４項目であり、下記基準により評価
した。結果を併せて表７に示す。 （評価基準） ◎：８名以上が良好と感じた。 ○：６名以上が良好と感じた。 △：４名以上が良好と感じた。 ×：３名以下が良好と感じた。(Test Method) Ten expert panelists actually used the cream prepared by the above-mentioned production method and conducted practical evaluation. The evaluation items are four items, which are goodness of finger, spread, familiarity with skin, and moist feeling, and evaluated according to the following criteria. The results are also shown in Table 7. (Evaluation Criteria) A: Eight or more people felt good. ◯: 6 or more people felt good. Δ: 4 or more people felt good. X: 3 or less people felt that they were good.
【００５２】[0052]
【表７】 [Table 7]
【００５３】上記結果から、本発明化粧料は、皮膚に対
し優れた感触を与えるものであることがわかる。From the above results, it can be seen that the cosmetic of the present invention gives an excellent feel to the skin.
【００５４】実施例４及び比較例６〜７ 表８に組成を示すクリームを実施例１と同様に製造し、
実施例１と同様に保湿持続効果を調べた。結果を併せて
表８に示す。Example 4 and Comparative Examples 6 to 7 Creams having the compositions shown in Table 8 were produced in the same manner as in Example 1,
The moisturizing retention effect was examined in the same manner as in Example 1. The results are also shown in Table 8.
【００５５】[0055]
【表８】 [Table 8]
【００５６】上記結果から、本発明化粧料は、グリセリ
ン等の保湿剤を特に添加しなくても、十分な保湿性を示
すことがわかる。From the above results, it can be seen that the cosmetics of the present invention exhibit sufficient moisturizing properties without the addition of moisturizing agents such as glycerin.
【００５７】実施例５〜７ 表９に組成を示すＷ／Ｏ型乳化化粧料を実施例１と同様
にして調製した。Examples 5 to 7 W / O type emulsion cosmetics whose compositions are shown in Table 9 were prepared in the same manner as in Example 1.
【００５８】[0058]
【表９】 [Table 9]
【００５９】上記化粧料はいずれも保湿性、使用感及び
保存安定性に優れるものであり、しかも皮膚に対する刺
激性をほとんど示さないものであった。All of the above cosmetics were excellent in moisturizing properties, feeling in use and storage stability, and showed almost no irritation to the skin.
Claims (1)
（Ｄ）； （Ａ）次の一般式（１） 【化１】 で表わされるアミド誘導体、 （Ｂ）次の一般式（２） 【化２】 で表わされる天然ステリン又はその水素添加物のジカル
ボン酸モノエステルの一種又は二種以上、 （Ｃ）油性物質 １０〜７０重量％、 （Ｄ）水 １０〜８８重量％、 を含有し、かつ（Ａ）／（Ｂ）が重量比で０．０１〜１
０であって、更に親水性の界面活性剤を実質的に含有し
ないことを特徴とする油中水型乳化化粧料。1. The following components (A), (B), (C) and (D); (A) The following general formula (1): An amide derivative represented by (B) the following general formula (2): One or more dicarboxylic acid monoesters of natural sterin represented by or a hydrogenated product thereof, (C) 10 to 70% by weight of an oily substance, (D) 10 to 88% by weight of water, and (A) ) / (B) is 0.01-1 by weight ratio.
A water-in-oil emulsion cosmetic, which is 0 and does not substantially contain a hydrophilic surfactant.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15733893A JP3271828B2 (en) | 1993-06-28 | 1993-06-28 | Water-in-oil emulsion cosmetics |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15733893A JP3271828B2 (en) | 1993-06-28 | 1993-06-28 | Water-in-oil emulsion cosmetics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH0710731A true JPH0710731A (en) | 1995-01-13 |
| JP3271828B2 JP3271828B2 (en) | 2002-04-08 |
Family
ID=15647510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15733893A Expired - Lifetime JP3271828B2 (en) | 1993-06-28 | 1993-06-28 | Water-in-oil emulsion cosmetics |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3271828B2 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2692334A1 (en) * | 2011-03-31 | 2014-02-05 | Kao Corporation | Vesicle composition |
| JP5917414B2 (en) * | 2011-01-05 | 2016-05-11 | 花王株式会社 | Cosmetics |
-
1993
- 1993-06-28 JP JP15733893A patent/JP3271828B2/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5917414B2 (en) * | 2011-01-05 | 2016-05-11 | 花王株式会社 | Cosmetics |
| EP2692334A1 (en) * | 2011-03-31 | 2014-02-05 | Kao Corporation | Vesicle composition |
| EP2692334A4 (en) * | 2011-03-31 | 2014-11-19 | Kao Corp | Vesicle composition |
| US9694076B2 (en) | 2011-03-31 | 2017-07-04 | Kao Corporation | Vesicle composition |
Also Published As
| Publication number | Publication date |
|---|---|
| JP3271828B2 (en) | 2002-04-08 |
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