JPH0698687A - Feed or nutrient composition for domestic animal - Google Patents

Abstract

PURPOSE:To provide a domestic animal feed containing beta-carotene and vitamin E at specific ratios, effective in preventing the breeding trouble, having excellent handleability and palatability and useful for the prevention and treatment of mammitis, diarrhea, etc. CONSTITUTION:The feed or nutrient composition for domestic animal contains beta-carotene and vitamin E at a weight ratio of 1/5 to 15 and preferably further contains vitamin A. Preferably, a domestic animal is fed with the feed at a daily rate of 0.2-0.8mg of beta-carotene, 2-10mg of vitamin E and 0-300IU of vitamin A based on 1kg of the body weight.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a feed or nutrition composition for livestock such as cattle containing β-carotene and vitamin E, and a method for feeding the feed or nutrition composition to livestock. Specifically, a feed or nutritional composition having a great effect on the treatment and prevention of reproductive disorders and mastitis in livestock, the reduction of somatic cell count in milk, the treatment and prevention of diseases such as diarrhea, and a method of feeding the livestock. Regarding

Reproductive disorders, diarrhea and other diseases and mastitis in dairy cows often occur in the livestock industry and there has been a strong demand for early resolution of these problems. Reproductive disorders include premature abortion, decreased conception rate, delayed ovulation,
It is caused by embryonic death, weakened estrous signs, decreased production of luteinizing hormone, etc., and when mastitis occurs, the number of somatic cells in milk expressed increases and the commercial value of milk (milk) is increased. Although it significantly decreases, various vitamins and minerals or combinations of these have been added to drinking water and feed to treat livestock such as cattle for the treatment and prevention of reproductive disorders and mastitis. Have been paid.

However, the conventional combination of vitamins and minerals cannot be said to be sufficiently effective in treating and preventing the occurrence of diseases such as reproductive disorders, mastitis and diarrhea in livestock, and it is difficult to handle them. Is also inferior in terms,
It has been required to develop highly effective ones for the treatment and prevention of diseases such as reproductive disorders, mastitis and diarrhea.

[0004]

The present inventors have continued their research under the above circumstances. As a result, a feed or nutritional composition produced by combining β-carotene with about 5 times or more that amount of vitamin E has good handleability, is easy to feed to livestock, and is preferred by livestock. It was found to be extremely superior to the conventional ones, especially in the recovery and prevention of reproductive disorders and mastitis in cows and the treatment and prevention of diseases such as diarrhea in young livestock. Further, the present inventors have found that the effect is further improved when vitamin A is further contained in such a feed or nutritional composition.

Further, the present inventors, when β-carotene, vitamin E and vitamin A were supplied to livestock in an amount within a specific range, the effects of treating and preventing diseases such as reproductive disorders, mastitis and diarrhea were more excellent. The present invention has been completed by finding that it will become a product.

[0006] That is, the present invention is a livestock feed or nutritional composition characterized by containing β-carotene and vitamin E in a weight ratio of 1: 5 to 15.

The present invention is also a feed or nutritional composition for livestock, which contains β-carotene and vitamin E in the above-specified proportions and further contains vitamin A.

Further, the present invention provides a domestic animal with the above-mentioned livestock feed or nutritional composition, β-
Carotene 0.2-0.8mg, Vitamin E 2-10mg and Vitamin A 0-
This is a method of supplying 300 IU (1 to 0.09 mg).

In the feed or nutritional composition of the present invention, β-
As described above, it is necessary to contain 5 to 15 parts of vitamin E with respect to 1 part by weight of carotene (hereinafter simply referred to as “part”). In particular, 1 part of β-carotene contains vitamin E. It is preferable to contain it in a ratio of 7 to 12 parts. By using vitamin E in combination at a ratio of 5 to 15 parts with respect to 1 part of β-carotene, the effect of promoting reproduction by β-carotene is exhibited well, and uterine restoration and ovaries after calving in cows and the like are performed. It is possible to achieve recovery of functions, shortening of estrus recurrence, decrease of placental stasis, prevention of miscarriage, prevention and reduction of mastitis, etc. Can be promoted. If the ratio of vitamin E to 1 part of β-carotene is less than 5 parts, the above-mentioned reproduction promoting function cannot be sufficiently exhibited. On the other hand, the upper limit of vitamin E is not particularly limited, and even if a large amount of vitamin E is fed, there is no fear of excess disease because the surplus only accumulates in body fat, but even if a large amount of vitamin E is fed Since the above effects cannot be obtained, it is desirable that the amount of vitamin E is 15 parts or less with respect to 1 part of β-carotene.

The β-carotene and vitamin E used in the present invention may be natural products or synthetic products. Especially, β-carotene is stable to heat and light and is easily available. It is desirable to use a synthetic product in view of the above.

The livestock feed or nutritional composition of the present invention may further contain vitamin A in addition to β-carotene and vitamin E. When vitamin A is contained, when the feed or nutritional composition of the present invention is fed to livestock, β-carotene in the feed or nutritional composition is converted into vitamin A in the body of the livestock and consumed. As a result, β-carotene fed as a feed or nutritional composition remains in the form of β-carotene in the body as it is, so the above-mentioned reproduction promoting function by m-carotene and mastitis decrease. The function and the like can be exhibited more favorably. If vitamin A is also used, β
-0.3 parts or less of vitamin A to 1 part of carotene,
It is preferably 0.1 to 0.2 part.

The livestock feed or nutritional composition of the present invention comprises:
From the viewpoints of handleability, ease of feeding livestock, and preference by livestock, in general, the size of the largest part is in the range of 1 to 10 mm and the size of the smallest part is in the range of 1 to 10 mm. Preference is given to granular pellets or granules. Particularly in the case of pellets, the diameter is 2 to 8 mm, preferably 2 to 4 mm, and the length is 3 to 9 mm, preferably 4 to
A pellet shape such as a 7 mm columnar body or a prismatic body is preferable. Also, in the case of nutritional composition other than pellets,
The shape may be a spherical shape, an elliptical shape, a cube, a rectangular parallelepiped, a cone, or any other shape, and the shape is not particularly limited. When the size of the pellets or the nutritional composition is larger than the above, when fed to livestock in addition to feed or the like, they are not well mixed in the feed and are likely not to be smoothly taken by the livestock. On the other hand, when the size is smaller than the above size, for example, when it is in the form of powder, the fluidity becomes poor and the handling becomes poor, and it becomes difficult to feed a predetermined amount to livestock.

The livestock feed or nutritional composition of the present invention comprises:
Vitamin E is blended in an amount of 5 to 15 parts with respect to 1 part of β-carotene, and a binding material such as cereal flour (wheat flour, starch, etc.), soybean flour, saccharides and water are added thereto, and further vitamin A, if necessary.
Add other ingredients and materials such as thickeners, minerals, seasonings, spices, grasses, etc., if necessary, pelletizing method by extrusion / cutting by ordinary method, granulation method by rolling or other method, or other It can be manufactured by any method.
When made into pellets or granules, a binder such as flour may be used in an amount of about 1 to 18 parts per part by weight of total β-carotene and vitamin E. If the amount of binder is less than 1 part, it becomes difficult to form pellets or granules.
When it is more than 8 parts, the contents of β-carotene and vitamin E are relatively decreased, and it becomes difficult to feed a predetermined amount of β-carotene and vitamin E to livestock. The water content in the pellets or granules is usually set to 10% or less, which is desirable from the viewpoints of storability, shape retention, handleability, and preference for livestock.

When feeding the feed or nutritional composition of the present invention to livestock, β-carotene, vitamin E and vitamin A which are fed to livestock as normal feed (that is, contained in normal feed) are used. Don't count
The amount of β-carotene fed in the form of the pellets or nutritional composition of the present invention is 0.2 to 0.8 mg, preferably 0.4 to 0.6 m per 1 kg of livestock weight per day.
g, the amount of vitamin E to be fed is 2 to 10 mg, preferably 3
~ 5 mg, and vitamin A dosage 0-300 IU
(0 to 0.09 mg), preferably 160 to 200 IU
If it is fed as described above, it is possible to more effectively carry out the above-mentioned recovery of reproductive disorders, promotion of reproduction, recovery and prevention function of mastitis, and treatment and prevention of diseases such as diarrhea. The above-mentioned salary for livestock should be approximately 3 every day or every other day.
It is recommended that you continue from day 0 to 3 months.

As a method for feeding the feed or the nutritional composition of the present invention, the feed may be directly fed to livestock and the nutritional composition may be fed directly as it is or may be fed by mixing with the feed or drinking water. , Especially mixed with feed and fed. The feed or nutritional composition of the present invention can be fed to livestock such as cattle, horses, pigs, goats, and sheep, thereby improving or impairing reproductive disorders of these livestock, and preventing or restoring mastitis. It can promote and prevent diarrhea and other diseases. In particular, when fed to a cow, the fertilization can be achieved in a short period of time due to its reproduction promoting (restoring) action. Furthermore, as a result of the rapid recovery of mastitis, the amount of somatic cells due to mastitis in the milk that has been expressed is reduced, and high-quality milk with a small number of somatic cells can be obtained.

[0016]

EXAMPLES The present invention will be specifically described below with reference to examples, but the present invention is not limited thereto.

<< Example 1 >> [Production of pellets] 60 g of "lucarotene 10%" (manufactured by BASF; β-carotene content 10%) 60 g, "Rutabit E50" (manufactured by Nisshin Badishe; content of vitamin E 50%) ) A mixture of 120 g and 820 g of wheat flour was fed to an extruder with 0.1 liter of water, which was kneaded, extruded into a rod shape, cut and dried, and pellets having a diameter of 3.2 mm and a length of 7 mm (moisture content: 9.5%).

Comparative Example 1 [Production of Pellet] A pellet having the same diameter, length and water content as in Example 1 was produced in the same manner as in Example 1 except that the amount of "Rabbit E50" was changed to 40 g. did.

Comparative Example 2 [Production of Pellet] "Rucarotene 10" was added without adding "Rutabit E50".
% ”Was added, and pellets having the same diameter, length and water content as in Example 1 were produced in the same manner as in Example 1.

Example 2 [Feeding test for pellets to cows] (1) Dairy cows (Holstein breed) considered to have latent mastitis, in which the number of somatic cells in milk is 4 × 10 ⁵ cells / ml or more 9
Heads (average body weight 640 kg / head) were prepared, and these were divided into 3 groups of 3 heads each. (2) For group 1 dairy cows, the amount of β-carotene fed is 300 mg / day, the head and the amount of vitamin E fed are 3
The pellets of Example 1 were added to the feed every other day so as to be 000 mg / day / head, and the feed was continued for 1 month. When the number of somatic cells in the milk expressed after one month was measured, the results shown in Table 1 below were obtained. (3) For the second group of dairy cows, the amount of β-carotene supplied is 300 mg / day, the head and the amount of vitamin E supplied are 1
The pellets of Comparative Example 1 were added to the feed every other day so as to be 000 mg / day / head, and the feed was continued for 1 month. When the number of somatic cells in the milk expressed after one month was measured, the results shown in Table 1 below were obtained. (4) For the third group of dairy cows, the pellet of Comparative Example 2 was added to the feed every other day so that the amount of β-carotene supplied was 300 mg / day / head, and the feed was fed. It continued for a month. When the number of somatic cells in the milk expressed after one month was measured, the results shown in Table 1 below were obtained.

[0021]

[Table 1]

From the results shown in Table 1 above, the pellets of the present invention containing 10 parts of vitamin E per 1 part of β-carotene are 300 mg of β-carotene and 3000 mg of vitamin E per day. In the first group of dairy cows fed in this manner, the number of somatic cells in the milk decreased to about 1/10 of the original one month after feeding, indicating that it was extremely effective in treating mastitis. .

On the other hand, in the case of the second group of dairy cows fed with the pellets of Comparative Example 1 which contained both β-carotene and vitamin E but had a lower vitamin E content than the pellets of the present invention. In comparison with the case of the first group of dairy cows fed the pellet of Example 1, the reduction rate of somatic cell number in milk is small, and the therapeutic effect of mastitis in dairy cows is low.

Further, in the case of the third group of cows containing the pellets of Comparative Example 2 which contained only β-carotene and no vitamin E, the first group which was fed with the pellets of Example 1
Compared with the case of dairy cows in the herd, the rate of decrease in somatic cell number in milk was extremely small, indicating that the therapeutic effect on mastitis in dairy cows was extremely low.

<Example 3> [Production of pellets] The same procedure as in Example 1 was repeated except that 4 g of "Rutabit A500" (manufactured by Nisshin Bertiche Co., Ltd .; vitamin A content: 500,000 IU / g) was used. 3.2 mm, 7 mm long pellets (water content 9.2%) were produced.

Example 4 [Feeding test for pellets to cows] (1) 7 heifers (average weight 640 kg / head) who were diagnosed as having a reproductive disorder with 72-229 days of gestation and treated.
Was prepared (the normal gestation period of healthy cows without reproductive disorders is about 60
~ 90 days). (2) For 5 cows among them, the amount of β-carotene was 300 mg / day / head, the amount of vitamin E was 3000 mg / day / head and the amount of vitamin A was 10 mg / day.
When the pellets of Example 3 were added to the feed every other day so as to give a dose of 10,000 IU (30 mg) / day / head, fertilization was carried out after the number of days shown in Table 2 below, counting from the pellet feeding day. It became possible. (3) For the 6th cow, the amount of β-carotene was 300 mg / day, the amount of head and vitamin E was 10
When the pellets of Comparative Example 1 were added to the feed every other day so as to be 00 mg / day / head and fed, as shown in Table 2, the fertilized state was 91 after feeding the pellets.
It was the first day and it was not very effective in treating reproductive disorders. (4) The 7th cow was fed with the pellets of Comparative Example 2 added to the feed every other day so that the amount of β-carotene was 300 mg / day / head, and Table 2 As shown in (4), fertilization became possible on the 92nd day after the pellet was fed, and there was little effect on the treatment of reproductive disorders.

[0027]

[Table 2]

From the results shown in Table 2 above, the pellets of the present invention containing 10 parts of vitamin E and 0.1 part of vitamin A per 1 part of β-carotene were treated with β-carotene per day. 300mg, 3000mg vitamin E
In the 1st to 5th cattle fed with vitamin A of 100,000 IU, the empty period was shortened drastically and fertilization was promptly performed 14 to 60 days after the start of feeding the pellets of the present invention. Therefore, it can be seen that the pellets of the present invention are extremely effective in treating reproductive disorders.

On the other hand, in the case of the sixth cow fed with the pellets of Comparative Example 1 which contained both β-carotene and vitamin E, but had a lower content of vitamin E than the pellets of the present invention. Requires a long period of 91 days to be in a fertilizable state as compared with the 1st to 5th cattle fed with the pellets of Example 3, and may not be very effective in treating reproductive disorders. Recognize.

Furthermore, in the case of the 7th cattle containing the pellets of Comparative Example 2 containing only β-carotene and not containing vitamin E, the period until fertilization was still 9
It is as long as 2 days and it can be seen that there is almost no effect in eliminating reproductive disorders.

[0031]

INDUSTRIAL APPLICABILITY The feed or nutritional composition of the present invention is used for the treatment and prevention of reproductive disorders and mastitis in livestock, especially cows.
It is extremely effective in reducing the number of somatic cells in milk and treating and preventing diseases such as diarrhea in young livestock. Since the feed or nutritional composition of the present invention contains β-carotene, vitamin E, and optionally vitamin A at a specific ratio extremely effective for the treatment and prevention of the above-mentioned symptoms and diseases in livestock, There is no need to measure and mix β-carotene, vitamin E and the like each time the animal is fed, and the feed or nutritional composition of the present invention is directly mixed with the feed or a predetermined amount of feed or the like. Diseases such as reproductive disorders, mastitis and diarrhea in livestock can be easily treated or prevented.

In particular, the feed or nutritional composition of the invention is
The amount of β-carotene is 0.2 to 0.8 mg and the amount of vitamin E is 2 to 1 kg / day of livestock.
Reproductive disorders in livestock, when 10 mg and vitamin A are supplied so as to be 0 to 300 IU.
It is possible to more effectively treat and prevent diseases such as mastitis and diarrhea.

Claims (3)

[Claims] 1. β-carotene and vitamin E in a ratio of 1: 5-1
A livestock feed or nutritional composition, characterized in that it is contained in a weight ratio of 5. 2. The livestock feed or nutritional composition according to claim 1, further comprising vitamin A. 3. The feed or the nutritional composition according to claim 1 or 2 is added to livestock in an amount of 0.2 to 0.8 mg of β-carotene and 2 to 0.8 mg of vitamin E per 1 kg of body weight per day. The amount of 10mg and vitamin A is 0 to 30
How to pay to get 0 IU.