JPH069363A - Medicinal cosmetic - Google Patents

Abstract

PURPOSE:To provide the medicinal cosmetic useful for preventing the exacerbation of chronic acne, eczema or dermatitis by adding zinc oxide to cosmetic materials. CONSTITUTION:30-60wt.% of zinc oxide as an active ingredient is added to the materials of a cosmetic such as a cream, pack, emulsion or foundation to provide the medicinal cosmetic. The medicinal cosmetic is used for men having skin natures susceptible to acne, eczema, dermatitis, etc., or for the serious patients of the eczema or dermatitis requiring special treatments as a daily cosmetic without being used as an external medicine, thereby permitting to protect the skins, improve the syndromes and prevent the exacerbation of the syndromes. The medicinal cosmetic can prevent the skins from external factors, e.g. allergic factors such as pollen, mites, sweats, or UV rays which cause subcorneal disorders.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to a cosmeceutical product, and more particularly to a cosmeceutical product used for patients with acne, eczema, dermatitis and the like.

[0002]

BACKGROUND OF THE INVENTION Zinc oxide, also called zinc white, has local astringent, anti-inflammatory, protective and mild antiseptic effects on the skin, and has long been used as an external therapeutic agent for skin eczema, wounds, dermatitis, etc. It is used and is known to have no side effects even after long-term use. As a general topical drug, powder
Used as an ointment, liquid (suspension, lotion, liniment) and the like.

In the case of chronic severe cases of skin diseases, especially acne, eczema, and dermatitis, various side effects may occur when a dermatological specialty treatment using antibiotics, hormones and the like is applied for a long period of time. Therefore, treatment is often forced to stop when the symptoms have subsided, and
Because patients themselves do not want to be treated for a long period of time, these often become chronic diseases, they do not completely cure, and they often relapse soon. Particularly in female patients, if these lesions are present on the face, they tend to thickly apply makeup to some extent to hide them inconspicuously, resulting in worsening of acne and cosmetic rashes. This also means that the lesions will be exacerbated chronically. Therefore, even if the treatment is performed for a long period (3 months or more and 10 years), it is inevitable that relapse and remission are repeated and the treatment is further prolonged.

[0004]

DISCLOSURE OF THE INVENTION The present invention provides a person who has a skin quality such as acne, eczema, dermatitis or the like, or a severe case patient with acne, eczema, dermatitis, which is treated by professional treatment. The purpose of the present invention is to prevent and protect skin by using it as a cosmetic rather than an external medicine for those who have relieved, to improve and prevent these symptoms and to prevent relapse.

[0005]

To achieve the above object, the present invention is characterized in that cosmetic materials such as creams, packs, emulsions and foundations contain 30 to 6 zinc oxide.
0% (weight) is included. The present invention is preferably used for preventing relapse of acne, eczema and dermatitis. Basically, for preventing flare-up, especially for people who have a skin quality that is prone to acne, eczema, and dermatitis, or for patients with severe cases of acne, eczema, and dermatitis who have had their cases relieved by specialized treatment. It is suitable to be used as a cosmetic material.

[0006]

EFFECTS OF THE INVENTION According to the present invention, as a cosmetic for daily use, especially as a basic cosmetic, it is suitable for people who are prone to acne, eczema, and dermatitis, and for those who have severe cases, who are relieved by specialized treatment. By using it, it brings about the effect of preventing the flare-up of skin examination. External factors (pollen, mites, sweat, sweat,
It has an excellent protective effect that protects the skin from (UV rays, etc.), which makes it possible to lead damaged skin to healthy skin.

As a cosmetic material, particularly a basic cosmetic material, a solid, paste, or liquid material such as cream, pack, emulsion, lotion, foundation, etc., which is generally used for women or men, is appropriately selected and used. Zinc oxide is a crystalline powder, water, acetic acid, methanol,
Since it is almost insoluble in ethanol and ether, it is desirable to use a fine powder in the case of a liquid agent as a suspension containing an appropriate dispersant and suspending agent. Zinc oxide is uniformly mixed with these cosmetic materials in an amount of 30 to 60%, preferably 35 to 40% (by weight) by a known appropriate means to produce a cosmetic product.

When the content of zinc oxide is 30% or less, the therapeutic effect is not sufficient, and when it is 60% or more, the elongation at the time of application becomes poor and the material feels gritty, which is not preferable for cosmetics. Suspension of a large amount of zinc oxide is difficult with a liquid formulation, and the most preferred is a cream or pack containing about 40% zinc oxide.

Zinc oxide has hitherto been used not only as a topical drug for external use but also as a powder pigment in some cosmetics together with talc, kaolin, titanium oxide, iron oxide, general organic pigments, creams, packs, In general, cosmetics such as milky lotion and foundation are generally mixed in only a few percent.

According to the invention, these cosmetics are used in an amount of at least 30%, which is more than the usual amount, preferably 3%.
It is characterized by being blended in a large amount of 5% or more to make a cosmetic for suppressing flare-up of acne, eczema and dermatitis. Women's cosmetics are especially desirable as cosmetics, and in the case of females, peculiar cases of pimples are likely to cause an exacerbation of skin lesions before menstruation due to imbalance of female hormones, and there are many cases of gastrointestinal disorders. These symptoms are prominent after administration of the substance. Further, in chronic eczema and dermatitis, administration of hormones makes it difficult to completely cure and prolongs the period, often causing a cosmetic rash.

Since the present invention is a cosmeceutical product, it is effective against these chronic diseases by applying daily makeup, and various symptom improvement was observed even within 1 month after application. At the same time, it has an effect of preventing so-called makeup rash caused by cosmetics. In addition, people with skin qualities that are prone to eczema, dermatitis, and rashes of makeup can be safely used for a long period of time.

Cosmetic materials include cream, pasta,
Suitable examples include packs, emulsions, foundations, etc., but solids such as creams and packs and pastes are more suitable because of the large amount of zinc oxide compounded. These are commonly used components such as liquid paraffin as oil, ceresin, wax, lanolin, petrolatum, cetanol, squalene, jojoba oil, stearic acid, palmitic acid, lauryl alcohol, stearyl alcohol, cetyl alcohol, beeswax, methyl polysiloxane, Dimethylcyclopolysiloxane etc. are used, and moisturizing propanol, glycol, propylene glycol, hyaluronic acid, collagen, polyethylene glycol, cholesteryl hydroxystearate, glycerin, sorbitol and other various surfactants, emulsifiers, powdering agents, pH adjustment Agents, antioxidants, dyes, fragrances, ultraviolet absorbers and the like may be appropriately mixed.

[0013]

From the above, according to the present invention, by applying zinc oxide as an active ingredient of a cosmeceutical product, unlike conventional topical medicines, it is routinely applied as a cosmetic product to prevent chronic skin troubles. We have been able to provide a cosmeceutical product that has the meaning to save the skin of women or men who have long been worried and even gave up.

[0014]

EXAMPLES Next, examples of the present invention and test results thereof will be described. Females aged 18 to 47 as a reference 3
The test examples that provided the present invention per 0 examples are shown below. Three
Among 0 cases, 20 cases of acne and 10 cases of eczema / dermatitis group were included.

(Major past symptoms of cases) (1) About 20 cases of acne group Presence or absence of premenstrual deterioration of skin lesions: It was observed in 20 cases out of 20 cases. One of them had undergone oophorectomy for left ovarian cyst. Exacerbation of the skin eruption due to disturbance of hormone balance was observed in all cases. Gastrointestinal disorders: found in 15 of 20 cases. Constipation, diarrhea, and stomach pain are the main symptoms, and when taking oral medicine such as antibiotics for acne treatment, notable gastrointestinal symptoms appear in 10 cases.
It was found in half of the cases.

(2) Ten cases of eczema / dermatitis group 8 cases out of 10 cases with pious treatment with hormones. There was a history of cosmetic rash in 7 of the 10 cases.

(Disease Duration of 30 Cases) 3 months to 10 years or more During this period, 15 out of 30 patients had repeated relapse and remission even though they visited a specialist and received treatment.

(Cosmetic manufacturing method) Cosmetic (a) Cream component Plastibase 50% Monostearic acid glyceride 2.5% Polyoxyethylene sorbitan-monostearic acid ester 1.5% 1.3-Butylene glycol 5% Perfume slightly zinc oxide 40% water remaining

Production method Plastibase is dissolved by heating at 80 ° C., and an emulsifier,
Add a mixture of glycol, fragrance and water to pre-emulsify, add zinc oxide and homogenize with a homomixer, then 3
Cool to 0 ° C. to obtain a cream.

Cosmetics (b) Pack composition Polyvinyl alcohol 15% Carboxymethylcellulose 5% Propylene glycol 3% Ethanol 2% Perfume A little zinc oxide 40% Water remaining amount

Manufacturing Method Mixing each component other than zinc oxide, heating to 70 ° C. and adding zinc oxide by vigorous stirring to homogenize and cool to obtain a product.

(How to use) The zinc oxide-containing cream of cosmetics (a) was used in the morning, evening,
Apply externally after lotion twice a day. The amount used once is
The size of rice grain was made. When the exacerbation of the rash was observed, such as during premenstrual exacerbation, the pack of cosmetics (b) was used. It was used 9 times a month on average. * For basic cosmetics other than this cream, we asked them to continue using the conventional cosmetics, and used conventional cosmetics (commercially available products Kao Sofina, Clinique, Azare, Shiseido, Max Factor, Kanebo). We compared it with the symptoms when it was struck. In addition, the effect was judged after the discontinuation of the oral administration in the severe cases in which the oral treatment was preceded and the disease duration was 5 to 10 years.

(Period of use) 3 months or more

(Test Results) (1) Within one month after use, the size of each eruption during pre-menstrual exacerbation was reduced to about half in all cases of the acne group, resulting in strong inflammation as before use. No increase was observed. Thereafter, within an average of 3 months, in addition, a dramatic reduction in new skin rash was observed. After that, even if the skin rash temporarily recurred due to some factor, the conventional deterioration was no longer observed. On the other hand, in the case of using conventional cosmetics, the symptoms of premenstrual exacerbation of pimples were observed as usual.

(2) Eczema / dermatitis group Within 1 week to 1 month of use, all the cases were found to reduce erythema and itchiness of the skin rash. Regardless of seasonality and physical condition (sleep, diet, etc.), the recurrence of the rash was not observed as much as before, and the frequency of itching, erythema, etc. decreased.

(Study of irritation of external preparation and allergic reaction) 24-hour closed patch test (white petrolatum was used as a control). All 30 cases were negative. No irritation or allergic reaction was observed during the use test.

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Claims (3)

[Claims] 1. A cosmeceutical product containing 30 to 60% (by weight) of zinc oxide in a cosmetic material such as a cream, a pack, an emulsion or a foundation. 2. The cosmeceutical product according to claim 1, which is used for preventing relapse of acne, eczema and dermatitis. 3. For preventing flare-up, for a person who has a skin quality that is prone to acne, eczema, dermatitis, or a patient with severe cases of acne, eczema, and dermatitis whose case has been relieved by professional treatment. Used as a basic cosmetic material in
The cosmeceutical product described.