JPH0679596B2 - Radiation tomography device - Google Patents
Radiation tomography deviceInfo
- Publication number
- JPH0679596B2 JPH0679596B2 JP60216377A JP21637785A JPH0679596B2 JP H0679596 B2 JPH0679596 B2 JP H0679596B2 JP 60216377 A JP60216377 A JP 60216377A JP 21637785 A JP21637785 A JP 21637785A JP H0679596 B2 JPH0679596 B2 JP H0679596B2
- Authority
- JP
- Japan
- Prior art keywords
- ray
- image
- tomographic
- tomographic plane
- plane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000005855 radiation Effects 0.000 title claims description 13
- 238000003325 tomography Methods 0.000 title claims description 4
- 238000007689 inspection Methods 0.000 claims description 9
- 239000000470 constituent Substances 0.000 claims description 6
- 239000003550 marker Substances 0.000 claims description 5
- 230000001678 irradiating effect Effects 0.000 claims description 2
- 238000003745 diagnosis Methods 0.000 description 9
- 239000003814 drug Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 3
- 210000004556 brain Anatomy 0.000 description 2
- 238000009513 drug distribution Methods 0.000 description 2
- 230000000877 morphologic effect Effects 0.000 description 2
- AFLDFEASYWNJGX-UHFFFAOYSA-N 1-(4-iodophenyl)-n-propan-2-ylpropan-2-amine;hydrochloride Chemical compound Cl.CC(C)NC(C)CC1=CC=C(I)C=C1 AFLDFEASYWNJGX-UHFFFAOYSA-N 0.000 description 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000003727 cerebral blood flow Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 238000009206 nuclear medicine Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
Landscapes
- Analysing Materials By The Use Of Radiation (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Description
【発明の詳細な説明】 産業上の利用分野 この発明は、医療の診断等に用いられる測定装置に関
し、特に放射線を利用して断層像を得る放射線断層測定
装置に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a measuring device used for medical diagnosis and the like, and more particularly to a radiation tomographic measuring device for obtaining a tomographic image by utilizing radiation.
従来の技術 従来より、患者の医学的診断を行なうために、Ｘ線CT装
置や、ガンマカメラやECT装置等の核医学診断装置が用
いられてきている。Ｘ線CT装置は形態診断に有用であ
り、ECT装置は臓器等の機能診断に有用であることが知
られている。2. Description of the Related Art Conventionally, in order to make a medical diagnosis of a patient, an X-ray CT apparatus, a nuclear medicine diagnosis apparatus such as a gamma camera or an ECT apparatus has been used. It is known that the X-ray CT apparatus is useful for morphological diagnosis, and the ECT apparatus is useful for functional diagnosis of organs and the like.
そこで、最近では、Ｘ線CT装置での検査とECT装置での
検査との両方を行なうことが多くなっている。Therefore, recently, both the inspection by the X-ray CT apparatus and the inspection by the ECT apparatus are often performed.
発明が解決しようとする問題点 ところで、Ｘ線CT装置とECT装置とを用いる場合、検査
回数が増えて患者の負担を増大させる問題がある。Problems to be Solved by the Invention By the way, when the X-ray CT apparatus and the ECT apparatus are used, there is a problem that the number of examinations increases and the burden on the patient increases.
また、Ｘ線CT画像を得た断層面と、ECT画像を得た断層
面とが一致していることが、診断上求められているが、
従来のように別々の装置を用いなければならないとする
と、これを完全に一致させることは困難である。In addition, it is required for diagnosis that the tomographic plane where the X-ray CT image is obtained and the tomographic plane where the ECT image is obtained match,
This would be difficult to match exactly if separate devices had to be used as in the past.
この発明は、Ｘ線CT装置により形態診断とECT装置によ
るのと同等の機能診断を１回の検査で同時に行なうこと
ができ、２つのデータを得た断層面を完全に一致させる
ことのできる放射線断層測定装置を提供することを目的
とする。The present invention is a radiation capable of simultaneously performing morphological diagnosis by an X-ray CT apparatus and functional diagnosis equivalent to that by an ECT apparatus in one examination, and completely matching the tomographic planes obtained with two data. An object is to provide a tomographic measuring device.
問題点を解決するための手段 この発明による放射線断層測定装置では、構成原子また
は原子核がＸ線照射によって励起される検査標識体が分
布せしめられた被検体に対して、その被検体の所定の断
層面内でＸ線照射することによって透過Ｘ線強度に関す
るデータを得、該データを用いて画像再構成することに
より上記の断層面でのＸ線CT画像を得るＸ線CT装置と、
上記のＸ線照射によって励起された、上記の断層面に分
布した検査標識体の構成原子または原子核から放射され
る放射線を、上記の断層面に対して実質的に直角な方向
から測定して検査標識体の分布を表わす断層像を得るガ
ンマカメラとを具備されている。Means for Solving the Problems In the radiation tomography apparatus according to the present invention, a predetermined slice of the subject is distributed to a subject in which an inspection marker whose constituent atoms or atomic nuclei are excited by X-ray irradiation is distributed. An X-ray CT apparatus that obtains data on a transmitted X-ray intensity by irradiating X-rays in a plane and obtains an X-ray CT image on the tomographic plane by reconstructing an image using the data
Inspection by measuring the radiation emitted from the constituent atoms or atomic nuclei of the inspection label distributed on the tomographic plane, which is excited by the X-ray irradiation, from a direction substantially perpendicular to the tomographic plane. And a gamma camera for obtaining a tomographic image showing the distribution of the marker.
作用 Ｘ線CT装置では、被検体の所定の断層面に対してＸ線照
射し、被検体の透過Ｘ線強度に関するデータを収集し
て、これを用いて画像再構成することによって、その断
層面でのＸ線吸収率分布を表わすＸ線CT画像を得る。と
ころで、この被検体には所定の検査標識体が分布せしめ
られており、この検査標識体というのは、その構成原子
または原子核がＸ線照射によって励起されるというもの
である。そして、上記のＸ線CT装置による検査では、上
記の通り、Ｘ線は特定の断層面にのみ照射される。つま
り、被検体内に分布している検査標識体のうち、この断
層面内に存在するもののみが励起されることになる。そ
の結果、Ｘ線照射された断層面のみからＸ線またはγ線
が放出される。そこで、この放射線をガンマカメラで測
定すれば、上記の断層面における放射線カウントの分布
データが得られる。この分布データによって作られる画
像は検査標識体の分布を表わすもので、ECT画像と同等
の断層像となる。Action An X-ray CT apparatus irradiates a predetermined tomographic plane of a subject with X-rays, collects data on the intensity of transmitted X-rays of the subject, and reconstructs an image using the data, thereby reconstructing the tomographic plane. An X-ray CT image showing the X-ray absorptivity distribution at is obtained. By the way, a predetermined test label is distributed in the subject, and the test label means that its constituent atoms or atomic nuclei are excited by X-ray irradiation. Then, in the inspection by the X-ray CT apparatus, as described above, the X-ray is irradiated only on the specific tomographic plane. In other words, among the test markers distributed in the subject, only those existing in this tomographic plane are excited. As a result, X-rays or γ-rays are emitted only from the X-ray-irradiated tomographic plane. Therefore, if this radiation is measured with a gamma camera, the radiation count distribution data on the above-mentioned tomographic plane can be obtained. The image created by this distribution data represents the distribution of the inspection marker and is a tomographic image equivalent to the ECT image.
そして、このガンマカメラで得た断層像は、Ｘ線照射し
てＸ線CT画像を得た断層面についてのものであるから、
両画像の断層面は完全に一致していることになる。Since the tomographic image obtained by this gamma camera is for the tomographic plane obtained by X-ray irradiation to obtain an X-ray CT image,
This means that the tomographic planes of both images are completely in agreement.
実施例 図において、被検者４にはあらかじめ検査薬剤が投与さ
れており、この薬剤が被検者４の脳内で分布５のように
分布している。この検査薬剤は検査標識体として働くも
ので、たとえば、Ｎ−イソプロピル−Ｐ−ヨードアンフ
ェタミン塩酸塩（以下IMPと略す）を使用する。この脳
内分布５は脳血流を示す（なお、ここではIMPは放射性
同位元素で標識されていないが、IMPにはこのような性
質があるため、123Iで標識した123I−IMPが核医学の分
野で使用されはじめている）。In the figure, the test drug has been administered to the subject 4 in advance, and this drug is distributed in the brain of the subject 4 as distribution 5. This test agent works as a test label, and for example, N-isopropyl-P-iodoamphetamine hydrochloride (hereinafter abbreviated as IMP) is used. This shows the brain distribution 5 cerebral blood flow (Although IMP is not labeled with a radioisotope here, since the IMP have such properties, 123 I-IMP nuclear labeled with 123 I Has begun to be used in the field of medicine).
そして、この被検者４の頭部をＸ線CT装置10で検査す
る。このとき、Ｘ線CT装置10の後方にガンマカメラ３を
配置しておく。Ｘ線CT装置10はガントリ11の内部にＸ線
管１と検出器２とを有し、これらがガントリ11内で、被
検者４が挿入されたトンネル部の周囲をスキャンするよ
うにされている（ガントリ11内にＸ線管１と検出器２と
をスキャンさせる機構が内蔵されている）。Then, the head of the subject 4 is inspected by the X-ray CT apparatus 10. At this time, the gamma camera 3 is arranged behind the X-ray CT apparatus 10. The X-ray CT apparatus 10 has an X-ray tube 1 and a detector 2 inside a gantry 11, and these are configured to scan inside the gantry 11 around the tunnel portion into which the subject 4 is inserted. (The gantry 11 has a built-in mechanism for scanning the X-ray tube 1 and the detector 2).
断層面６におけるＸ線CT断層像を得ようとする場合、Ｘ
線管１からのＸ線７が断層面６内にのみ照射される。そ
のため、IMPの体内分布５のうち、断層面６の部分に存
在しているIMPのみにＸ線が照射されて、IMPの構成原子
であるＩ（ヨウ素）のＫ Ｘ線（Ｋαは28.6keV）８が
放出される。When trying to obtain an X-ray CT tomographic image on the slice plane 6,
The X-ray 7 from the ray tube 1 is irradiated only on the tomographic plane 6. Therefore, of the IMP body distribution 5, only the IMP existing on the fault plane 6 is irradiated with X-rays, and the K X-rays of I (iodine), which is a constituent atom of IMP, (Kα is 28.6 keV). 8 is released.
Ｘ線CT装置10の後方にはガンマカメラ３が配置されてい
るため、この放出Ｘ線８がガンマカメラ３で検出される
ことになる。このガンマカメラ３は、たとえば平行多孔
コリメータとシンチレータとを使用したものであり、通
常は放射性同位元素の体内での濃度分布を１平面（検出
面）に投影したような平面像を得るのに用いられるもの
である。ところが、ここでは、IMPは断層面６以外の場
所では励起されないので、ガンマカメラ３で得られる画
像は、断層面６でのIMPの分布像、つまり断層面６でのE
CT像と同等なものとなる。しかも、Ｘ線CT像とこのガン
マカメラ３で得た画像は、全く同一な断層面６について
のものであるから、両画像で断層面が一致しないという
ことは起り得ない。Since the gamma camera 3 is arranged behind the X-ray CT apparatus 10, the emitted X-rays 8 are detected by the gamma camera 3. The gamma camera 3 uses, for example, a parallel porous collimator and a scintillator, and is usually used to obtain a plane image in which the concentration distribution of radioisotopes in the body is projected on one plane (detection surface). It is what is done. However, since the IMP is not excited at a place other than the tomographic plane 6 here, the image obtained by the gamma camera 3 is an IMP distribution image on the tomographic plane 6, that is, E on the tomographic plane 6.
It is equivalent to a CT image. Moreover, since the X-ray CT image and the image obtained by this gamma camera 3 are for the same tomographic plane 6, it is impossible for the two images to have different tomographic planes.
なお、ガンマカメラ３は、シンチレータを使用した通常
のものでなく、マルチワイヤ比例計数管あるいはその他
の放射線検出器を利用した他のタイプのガンマカメラで
もよい。The gamma camera 3 is not limited to a normal one using a scintillator, but may be another type of gamma camera using a multi-wire proportional counter or other radiation detector.
また、Ｘ線CT装置10でなく、一般のＸ線撮影装置を使用
することもできる。この場合は平面的なＸ線透過像と薬
剤分布の平面像とが得られ、両方とも断層像ではない。Further, instead of the X-ray CT apparatus 10, a general X-ray imaging apparatus can be used. In this case, a flat X-ray transmission image and a flat image of the drug distribution are obtained, and both are not tomographic images.
発明の効果 この発明の放射線断層測定法によれば、断層面の位置の
不一致の問題を生じない、Ｘ線CT画像と、ECT画像に同
等な断層像とを１回の検査で簡単に得ることができる。
そのため検査回数が少なくなり患者の負担が軽減する。
また、両画像の断層面、時間が一致するので、正確な診
断が可能となる。さらに、薬剤を放射性同位元素で標識
しないので安価であり、しかも半減期がないので使用時
期の制限もない。EFFECTS OF THE INVENTION According to the radiation tomography measurement method of the present invention, an X-ray CT image and a tomographic image equivalent to an ECT image can be easily obtained in a single examination without causing the problem of inconsistency in the positions of tomographic planes. You can
Therefore, the number of examinations is reduced and the burden on the patient is reduced.
Further, since the tomographic planes and the times of both images coincide with each other, accurate diagnosis is possible. Furthermore, since the drug is not labeled with a radioisotope, it is inexpensive, and since it has no half-life, there is no limitation on the time of use.
図はこの発明の一実施例を説明するための模式図であ
る。 １……Ｘ線管、２……検出器 ３……ガンマカメラ、４……被検者 ５……薬剤分布、６……断層面 ７……Ｘ線、８……放射線 10……Ｘ線CT装置、11……ガントリThe figure is a schematic view for explaining an embodiment of the present invention. 1 ... X-ray tube, 2 ... Detector 3 ... Gamma camera, 4 ... Subject 5 ... Drug distribution, 6 ... Tomographic plane 7 ... X-ray, 8 ... Radiation 10 ... X-ray CT device, 11 ... Gantry
Claims (1)
励起される検査標識体が分布せしめられた被検体に対し
て、その被検体の所定の断層面内でＸ線照射することに
よって透過Ｘ線強度に関するデータを得、該データを用
いて画像再構成することにより上記の断層面でのＸ線CT
画像を得るＸ線CT装置と、上記のＸ線照射によって励起
された、上記の断層面に分布した検査標識体の構成原子
または原子核から放射される放射線を、上記の断層面に
対して実質的に直角な方向から測定して検査標識体の分
布を表わす断層像を得るガンマカメラとを備えることを
特徴とする放射線断層測定装置。1. A transmitted X-ray is obtained by irradiating an object in which a test label whose constituent atoms or atomic nuclei are excited by X-ray irradiation are distributed, with X-rays within a predetermined tomographic plane of the object. X-ray CT on the above-mentioned tomographic plane is obtained by obtaining data on intensity and reconstructing an image using the data.
An X-ray CT apparatus for obtaining an image, and the radiation emitted from the constituent atoms or atomic nuclei of the inspection marker distributed on the tomographic plane, which is excited by the X-ray irradiation, is substantially applied to the tomographic plane. And a gamma camera that obtains a tomographic image showing the distribution of the inspection marker from a direction perpendicular to the radiation tomography apparatus.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60216377A JPH0679596B2 (en) | 1985-09-30 | 1985-09-30 | Radiation tomography device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60216377A JPH0679596B2 (en) | 1985-09-30 | 1985-09-30 | Radiation tomography device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6274339A JPS6274339A (en) | 1987-04-06 |
| JPH0679596B2 true JPH0679596B2 (en) | 1994-10-12 |
Family
ID=16687615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60216377A Expired - Lifetime JPH0679596B2 (en) | 1985-09-30 | 1985-09-30 | Radiation tomography device |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0679596B2 (en) |
-
1985
- 1985-09-30 JP JP60216377A patent/JPH0679596B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6274339A (en) | 1987-04-06 |
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