JPH067409A - Container of medicine - Google Patents

Abstract

PURPOSE:To provide a container of medicine useful for cold-drying, storing, and preparing a medicinal agent by providing a main plug formed with airtight coupling sections with the opening section of the container and having a piercing needle at the center section, an auxiliary plug provided at the tip section of the piercing needle and airtightly sealing a needle hole, and a cap airtightly covering the auxiliary plug and the main plug. CONSTITUTION:A chemical container is constituted of a container main body 10, a main plug 20 formed with inside and outside airtight coupling sections 26, 28 together with the opening section 12 of the container and provided with a piercing needle 22 at the center section, an auxiliary plug provided at the tip section of the piercing needle 22 and sealing a needle hole, and a cap 30 aritightly covering the piercing needle 22 including the auxiliary plug and the main plug 20. This container is utilized as the cold-drying unit of a medicine and its storage container. When the filled medicine is to be used, the cap 30 is removed, this container is immediately communicated with another container via the piercing needle 22 provided on the main plug 20, and the required medicinal agent can be delivered or prepared.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention mainly relates to a medical drug container, and more particularly to a drug container useful for storing, preparing and freeze-drying a drug.

[0002]

2. Description of the Related Art A glass bottle is generally used as a drug container of this kind, and the opening of the drug-loaded container is sealed with a rubber stopper which can be pierced by an injection needle or the like. Is caulked with a soft metal foil such as aluminum and covered with a plastic cap. Such drug containers are heavily used as storage containers for frozen drugs, such as antibiotics, vaccines, serum, microorganisms,
When used in the medical field, the surface of the rubber stopper is cleaned or sterilized as needed before being used. For example, when using a syringe, the injection needle is pierced from the top of the rubber stopper, the solution or diluent of the drug loaded in the container is injected, or the drug is extracted from the drug container and transferred to another container, Prepare the required drug.

An infusion kit is used when it is necessary to prepare a drug in an airtight manner. FIG. 6 is a schematic view illustrating the case of using a typical infusion kit. As shown in the figure, a drug container 1 loaded with a drug has an inner cylinder 3 and an outer cylinder 4.
The opening 2 is stored inward (downward) in the holding container 5 constituted by. A piercing needle 6 is attached to the other end of the holding container 5.
The connecting portion 7 provided with is fixed, and the lower portion of the connecting portion 7 is connected to another drug container 8. Since the inner cylinder 3 is formed so as to slide in the outer cylinder 4 in an airtight manner, the rubber plug of the container 1 comes into contact with the piercing needle 6 by pushing the inner cylinder 3 into the outer cylinder 4. When the inner cylinder 3 is pushed further in, the piercing needle 6 pierces the rubber stopper of the opening 2, while the stopper 9 of the other container 8 connected to the piercing needle 6 pushes the connecting portion 7 by pressing the inner cylinder 3. The container 1 and the container 8 are connected via the stopper via the container 1, and the medicine is delivered between the container 1 and the container 8 through the piercing needle 6. For example, when the container 1 is loaded with the powdered drug and the container 8 is loaded with the sugar solution or the physiological saline, the required infusion solution for infusion is prepared by repeating the delivery.

[0004]

As described above, the conventional drug container has no particular problem in terms of function as a drug storage container, but when used, the structure of the cap must be purified or sterilized. In addition, an auxiliary tool such as a syringe is required for injecting and dispensing the drug. On the other hand, when using an infusion kit, it is preferable that it does not touch the outside air and eliminates the risk of puncture wounds that often occur when using a syringe, but kits of various sizes must be prepared. In addition to the storage, the cleaning process at the time of use is troublesome depending on the storage condition, and the cost associated with them and the cost of the kit itself cannot be neglected. Therefore, it is desired to solve these problems in the medical field.

[0005]

Means for Solving the Problems The present invention has been made to solve the above-mentioned problems, and in particular, the bacterial contamination and the contamination of foreign substances which are unavoidably generated during the preparation of a drug in a medical field are avoided. (EN) Provided is a drug container which is intended to prevent and reduce the danger and work load of a medical worker.

That is, according to the present invention, a container body, a main stopper which forms an airtight fitting portion with the opening of the container and which has a piercing needle in the center, and a needle provided at the tip of the piercing needle. A drug container having a sub-plug for hermetically sealing a hole and a cap for hermetically enclosing the sub-plug and the main plug.

In the present invention, the airtight fitting portion of the main plug is formed on the surface from the inner side surface to the outer side surface of the container body opening. The piercing needle is provided integrally with the main stopper, and the bottom portion of the main stopper is used as an opening end and rises from substantially the center of the main stopper. Is formed so as to project by a sufficient length. An annular groove for strengthening airtightness and an annular rib corresponding to the annular groove are provided on the fitting surface between the inner surface of the opening of the container body and the main plug. A ventilation groove for half stoppering is provided on the peripheral surface of the small diameter portion of the main plug extending downward from the vicinity of the annular groove or the annular rib. A sub-plug for closing the needle hole formed at the tip of the piercing needle may be provided separately or may be provided in the cap. The cap is attached to the outer circumference of the main plug so that it can be removed with one touch.

[0008]

As described above, in the medicine container according to the present invention, the medicine container and the main stopper are airtightly fitted on both the inner side surface and the outer side surface of the opening of the container body, and the piercing needle is integrally formed with the main stopper. The needle hole formed and provided at the tip of the piercing needle is sealed by a sub-plug, covered with a cap together with the main plug, and airtightly fitted to the outer periphery of the main plug. Therefore, in addition to having a function as a storage container for the drug, the main stopper itself is equipped with a piercing needle for preparation of the drug, so auxiliary devices such as a syringe and an infusion kit are used as in the conventional case. It is not necessary, and since the inside of the cap is maintained in a sterilized state, the drug can be delivered to and from another container immediately by simply removing the cap, and the required drug solution can be prepared easily and safely. Further, since the drug container of the present invention also has a function of half stoppering, it is also useful as a freeze-drying container.

[0009]

1 is a schematic sectional view showing the structure of a drug container according to an embodiment of the present invention. As shown in the figure, the drug container has a container body 10 and an opening 12, and is made of glass or plastic like a normal drug container. The main plug 20 is made of plastic, preferably semi-rigid plastic such as polyolefin, and is made of airtight fitting portions 26, 28.
And the piercing needle 22 are integrally formed.

FIG. 2 shows an enlarged front view (A) and a front sectional view (B) of the main plug 20. As can be understood from the drawing, the airtight fitting portion is from the inner side surface of the container opening 12. The inner fitting portion 26 and the outer fitting portion 28 are formed so as to cover a portion reaching the outer side surface. The inner fitting portion 26 is provided with an annular rib or groove 27 (a rib is shown in the figure) corresponding to the annular groove or rib provided on the inner surface of the container opening. The ribs or grooves have the effect of strengthening the airtight fitting and the effect of preventing accidental disengagement.

The piercing needle 22 rises from a substantially central portion with the bottom portion 21 of the main stopper 20 as an open end, and when the piercing needle 22 pierces a stopper of another container, a needle hole 24 provided at the piercing portion is a medicine. It is formed so as to project by a length long enough to function for pouring and pouring. The needle hole 24 provided at the tip of the piercing needle 22 is 1
However, in order to efficiently deliver the medicine, it is desirable to provide another needle hole 24 'substantially at the opposite position.

The lower portion of the inner fitting portion 26 of the main plug 20 is
The diameter is slightly smaller than the outer diameter of the inner fitting portion 26. The small-diameter portion 29 mainly contributes to half stoppering at the time of freeze-drying of the loaded medicine, and a plurality of half-venting vent holes 25 are provided on the outer periphery in the axial direction of the main stopper. Further, on the outer periphery of the main plug, a groove or rib 27 'that contributes to the airtight fitting with the cap 30 is provided (the figure shows the rib).

The cap 30 is formed of the same or different plastic material as the main plug 20. FIG. 3 shows a cap 30
It is the front view (A) and front sectional view (B) which show an example.
As shown in the figure, the cap 30 covers the entire main plug including the piercing needle and is airtightly fitted and fitted to the outer periphery of the main plug by a means that can be easily removed. The auxiliary plug 34 that closes the needle hole of the piercing needle is
It is made of rubber or soft plastic that can seal the needle hole. The sub-plug 34 can be used independently, but if it is mounted in the protective cylinder 36 provided in the cap 30 as shown in the drawing, the mounting and dismounting of the sub-cap 34 is performed following the mounting and dismounting of the cap. It is rational. In this case, the tip 37 of the protection tube 36 is
It is desirable that the piercing needle 22 be airtightly covered and contact the main plug. As a result, even if the medicine leaks due to the defect of the auxiliary plug 34, the protection cylinder 36 prevents the leakage of the medicine to other parts.

An engaging portion 32 of the cap 30 to the main plug 20
When an annular rib 27 'is provided on the outer periphery of the main plug 20 as illustrated, the annular groove 3 corresponding to the rib is formed on the cap side.
3 is provided. The annular groove or rib is useful for the airtight effect and preventing accidental detachment of the cap. Therefore, the desired effects are added by providing a plurality of threads for the annular groove and the annular rib, and by adopting the screwing method.

Further, it is desirable that the cap 30 can be attached and detached by a so-called one-touch method. To do that, cap 3
No. 0 is attached to the engaging fitting portion 32 to the main plug 20, for example, as shown in FIG.
As shown in (A), a normal tear-off ring 38 or the like may be adopted.

FIG. 4 is a cross-sectional view of the essential parts when the drug container constructed as described above is used for freeze-drying a drug. Freeze-drying is performed by loading a drug (not shown) into the container body 10 and degassing under cooling with the main stopper 20 held in a half stoppered shape as shown. At this time, deaeration is performed through the vent hole 25 (see FIG. 2A) formed in the lower small diameter portion 29 of the main plug 20. When the freeze-drying is completed, the cap 12 is closed to open the opening 12 of the container body 10.
As shown in FIG. 1, the main plug 20 hermetically covered with a cap 30 hermetically seals the entire surface from the inner side surface to the outer side surface and is provided for storage.

When a lyophilized drug is used, the cap 30 is removed from the main stopper via the tear-off ring 38, and the piercing needle 22 is replaced with another container 40 as illustrated in FIG.
The required drug is prepared by piercing the stopper of (1) and delivering the drug. 5 (A), (B) and (C) show examples of connection between a plastic bottle, a vial and a bag and the drug container according to the present invention, respectively.

[0018]

As can be understood from the above description, in the container of the present invention, the main stopper for closing the opening of the container main body has a highly airtight fitting portion and is formed integrally therewith. Since it has a piercing needle and a half stopper mechanism, and this main stopper is airtightly covered by a cap, it can be used not only as a freeze-drying container for medicines but also as a storage container for it.
When using the loaded drug, by removing the cap, the drug can be immediately communicated with another container through the piercing needle provided on the main stopper, and the required drug can be transferred and prepared.
Therefore, the drug container according to the present invention does not require any other auxiliary equipment unlike the conventional drug container, and can be put to practical use and function as a safe and efficient multifunctional drug container.

[Brief description of drawings]

FIG. 1 is a schematic cross-sectional view showing the structure of a drug container according to an embodiment of the present invention.

FIG. 2A is a front view of a main stopper. Figure 2 (B) is
It is a front sectional view of the main stopper shown in (A).

FIG. 3A is a front view of a cap. 3B is a front sectional view of the cap shown in FIG.

FIG. 4 is a partially omitted front sectional view showing a half-stoppered state.

FIG. 5 is a conceptual diagram of use of the drug container according to the present invention.

FIG. 6 is a conceptual diagram of use of a conventional drug container.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 10 Container main body 12 Opening part 16 Inner peripheral surface 18 Outer peripheral surface 20 Main stopper 21 Bottom part 22 Penetration needle 24 Needle hole 25 Ventilation groove 26 Inner fitting part 27 Annular rib (groove) 28 Outer fitting part 29 Small diameter part 30 Cap 32 Attachment fitting part 34 Sub stopper

Claims (5)

[Claims] 1. A container main body, a main stopper having an airtight fitting portion with the container opening and having a piercing needle in the center, and a needle hole provided at the tip of the piercing needle. A drug container, comprising: a sub stopper for sealing and closing, and a cap for hermetically enclosing the sub stopper and the main stopper. 2. The drug container according to claim 1, wherein the airtight fitting portion of the main stopper is formed on a surface extending from the inner surface to the outer surface of the container main body opening. 3. The piercing needle rises with the bottom of the main stopper as an open end, and the pointed end projects from the opening surface of the container.
The described drug container. 4. The medicine according to claim 1, wherein at least one annular groove and an annular rib corresponding to the groove are provided on an airtight fitting surface formed by the inner surface of the opening of the container body and the main stopper. container. 5. The drug container according to claim 1, wherein a plurality of semi-stopper ventilation grooves are provided on the outer peripheral surface of the small diameter portion formed below the main stopper that is in contact with the inner surface of the opening of the container body.