JPH0670975A - Set tool in living body - Google Patents

Abstract

PURPOSE:To allow a set tool to be arbitrarily taken outside a living body by the sample operation, when setting becomes useless or replacement becomes necessary, after setting the tool in the living body. CONSTITUTION:A closing tool 1 as set tool in a living body is constituted from the material which possesses high viscoelasticity when ultraviolet ray is not irradiated, while possesses low viscoelasticity and is fluidized in the irradiation of ultraviolet ray. In the set state, ultraviolet ray is not irradiated and the closing tool 1 possesses high viscoelasticity, while if the setting of the closing tool 1 becomes useless, ultraviolet ray is irradiated, and viscoelasticity is lowered, and fluidization occurs, and the setting tool can arbiararily be taken outside by the suction operation.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to improvement of an in-vivo indwelling device which is left in a living body for a medium to long term.

[0002]

2. Description of the Related Art The following is an in-vivo indwelling device that is left in the living body for a medium to long term. As an in-vivo indwelling device, a fallopian tube obturator that is placed in the fallopian tube for the purpose of contraception, a vascular splint used for vascular anastomosis, a clip used in a surgical operation to close luminal organs such as gallbladder ducts and blood vessels from the outer peripheral side, bile For example, there is an ERBD tube left in the bile duct for discharge.

[0003] Conventionally, for example, using a fallopian tube obturator, a bioadhesive made of silicone or the like is injected into the fallopian tube and cured,
A procedure for occluding the fallopian tube is known.

Further, as an ERBD tube to be placed in the bile duct for the purpose of excretion of bile, for example, Sekikaihei 1-15
As shown in Japanese Patent No. 2636, there is one in which the inner surface of the tube is formed of a fluororesin layer. As this tube, there is known a tube provided with side flaps, each of which is formed by cutting a part of a peripheral wall of the tube toward the front and rear end faces so as to incline in a direction that becomes deeper. And this ERB
The D tube is inserted and placed in the bile duct endoscopically.

On the other hand, as a clip used in a surgical operation to close a blood vessel or a gallbladder duct from the outer peripheral side,
As shown in JP-A-58-27548, there is a bioabsorbable material which is made of polycioxanone and is absorbed in the living body after a lapse of a certain time.

[0006]

However, since the conventional fallopian tube obturator injects and cures the bioadhesive into the fallopian tube, the contraceptive effect is permanently continued. For this reason, even if she wanted to become pregnant later, she could not open the fallopian tube.

Further, the conventional ERBD tube needs to be replaced endoscopically because its lumen is clogged with time. Then, snare or the like is hooked on the flap of the ERBD tube and removed from the bile duct. However, there is a risk that the flap may be broken when the tube is removed, and thus the tube body remains in the bile duct.

On the other hand, although the absorbable clip used for the surgical procedure is finally absorbed in the living body, its absorption rate cannot be set arbitrarily.

The present invention has been made in view of the above-mentioned problems, and its object is to remove it outside the body by a simple operation when it is no longer needed after being placed in a living body. An object is to provide a possible indwelling device in the living body.

[0010]

In order to achieve the above object, the indwelling device of the present invention has a high viscoelasticity when not irradiated with light and a low viscoelasticity when irradiated with light. It is composed of.

[0011]

In the in-vivo indwelling device of the present invention, in the storage or indwelling state, while keeping the viscoelasticity in a non-irradiated state,
When it is no longer needed, it is irradiated with light and sucked in a fluidized state with low viscoelasticity. With such a simple operation, the in-vivo indwelling device can be arbitrarily taken out of the body.

[0012]

Embodiments of the present invention will be described below with reference to the drawings. 1 to 3 relate to a first embodiment of the present invention, FIG. 1 is an explanatory view showing an indwelling of an obturator, FIG. 2 is an explanatory view showing an indwelling state of an obturator and recovery, and FIG. 3 is an obstruction recovery FIG.

The obturator 1 shown in FIG. 1 is a material whose viscoelasticity is reduced by irradiating it with ultraviolet rays, and is integrally formed in a substantially spherical shape. As the material whose viscoelasticity is changed, for example, as described in “Intelligent Material” CMC Publishing Co., Ltd. A photoviscosity changing material such as polyamide containing azobenzene (see FIG. 24) that undergoes a cis-type structural change is used.

For example, pyrrolidone (N-containing LiCl)
Polyamide II dissolved in a methyl-2-pyrrolidone solution gives an ultraviolet light (410>λ> 350n).
When irradiated with m), the viscosity decreases by 63%, and when exposed to light with λ = 470 nm or more, the viscosity returns to the original value.

The magnitude of the change in viscosity depends on the rigidity and length of the polymer chain bonded to azobenzene. That is, if the structure of the molecules that are bound is rigid,
A structural change in azobenzene is rapidly transmitted to the entire polymer chain, and a large change in viscosity is induced.However, when the molecular structure is flexible, the three-dimensional structure is absorbed by this morphological change in the molecular chain, and The morphology of the entire molecular chain does not change, and the change in viscosity is small.

Next, a method of using the obturator 1 made of a photoviscosity changing material such as polyamide containing azobenzene as described above will be described. First, the obturator 1 stored in the dark without light irradiation is taken out and grasped by the grasping forceps 2. Then, in the gripped state, the oviduct 3 is transendoscopically
Then, the grasping forceps 2 is opened, and the obturator 1 is left in the oviduct 3.

At this time, since the inside of the oviduct 3 is in a dark place, the azobenzene forming the obturator 1 is in a trans state and has a large viscoelasticity. Therefore, the obturator 1 occludes the fallopian tube 3 while maintaining its shape, and provides a patient with a contraceptive effect.

Next, the patient desires to become pregnant again and the obturator 1
The case of removing the egg from the oviduct 3 will be described. First, the endoscope 4 is inserted into the fallopian tube 3, ultraviolet light is sent from a light source (not shown), and the light guide 5 of the endoscope 4 irradiates the obturator 1 with ultraviolet light (see FIGS. 2 and 3). ). When the obturator 1 is irradiated with ultraviolet light, its viscoelasticity is reduced, and its shape cannot be maintained, and the obturator 1 is fluidized. Therefore, as shown in FIG. 3, the suction probe 7 is inserted into the oviduct 3 through the channel hole 6 of the endoscope 4, and the fluidized obturator 1 is suctioned and taken out of the body.

The obturator 1 of this embodiment is made of a material that has a high viscoelasticity when not irradiated with light and is fluidized due to a decrease in viscoelasticity when irradiated with light. If the indwelling becomes unnecessary, it can be taken out by a simple operation.

FIG. 4 is a sectional view of an obturator according to a modification of the first embodiment of the present invention. The obturator 1'shown in FIG. 4 is a central portion 1A made of an elastic material such as silicone or urethane.
And has a two-layer structure of an outer peripheral portion 1B made of a material that is formed so as to cover the outer peripheral portion thereof and has high viscoelasticity when not irradiated with light and decreases viscoelasticity when irradiated with light. It is formed in a shape.

The obturator 1'having such a structure is inserted and placed in the fallopian tube 3 endoscopically, as in the first embodiment, to provide a contraceptive effect.

When the patient desires to become pregnant again, the endoscope 4 is inserted, and ultraviolet light is emitted from the light guide 5 to the obturator 1 ', as in the first embodiment. When irradiated with ultraviolet light, the outer peripheral portion 1B of the obturator 1'fluidizes as described above. On the other hand, the central portion 1A keeps its shape.

As described above, the fluidized outer peripheral portion 1B is removed outside the body by the suction probe, while the central portion 1A is extracted outside the body by the grasping forceps 2 or the like.

The obturator 1'of this embodiment has an outer peripheral portion 1B.
Since it is made of a material whose viscoelasticity is reduced by light irradiation, if the obturator 1 ′ becomes unnecessary after being placed in the body, it can be taken out by a simple operation.

5 and 6 show an in-vivo indwelling device according to the second embodiment of the present invention. The indwelling device of the present embodiment,
This is an application to blood vessel splint.

The blood vessel splint 8 shown in FIG. 5 is formed in a tubular shape, and is suitable for portal vein reconstruction, treatment of obstructive cerebrovascular disease, and the like. Similar to the first embodiment, the blood vessel splint 8 is made of a material that has a high viscoelasticity when not irradiated with light and has a low viscoelasticity when irradiated with light and is fluidized. Further, both ends 8a and 8b of the blood vessel splint 8 are
It is formed so as to be cut obliquely to the axial direction and parallel to each other so as to be easily inserted into a blood vessel.

The blood vessel splint 8 constructed in this way is
It is taken out from the dark place and inserted so as to extend over both of the lumens of the first blood vessel 10 and the second blood vessel 11 to be joined.
The end portion 10a of the first blood vessel 10 and the end portion 11a of the second blood vessel 11 are brought into close contact with each other.

Next, a laser probe (not shown) is inserted into the tube of the blood vessel splint 8 and the vicinity of the ends 8a and 8b of the blood vessel splint 8 is irradiated with a YAG laser. By the YAG laser irradiation, the blood vessel splint 8 becomes the first blood vessel wall,
Each is fixed to the second blood vessel wall. At this time, since the splint 8 in the blood vessel is left in a dark place, it has high viscoelasticity and maintains its shape. The wavelength of the laser is a wavelength that does not reduce the viscoelasticity of the blood vessel splint 8.

After a certain period of time, the first and second blood vessels 10,
Since the respective end portions 10a and 11a of 11 are in close contact with each other, they are joined by the self-repairing function of the living body and the original blood vessel function is restored.

When the respective end portions 10a and 11a are joined, the endoscope 4 is inserted into the blood vessel splint 8 as shown in FIG.
Upon irradiation with ultraviolet light, the blood vessel splint 8 becomes less viscous and is in a fluidized state as in the first embodiment, and therefore is suctioned out of the body by the suction probe 7 inserted through the channel hole 6.

When the blood vessel splint 8 of this embodiment is no longer needed after being placed in the body as in the first embodiment, it is fluidized by light irradiation to reduce its viscosity and can be easily taken out. Become.

In this embodiment, the blood vessel reconstruction technique is described, but the same splint can be used for intestinal anastomosis, bile duct reconstruction, ureter reconstruction and the like.

Next, a third embodiment will be described. Figure 7
9 to 9 show an in-vivo indwelling device according to a third embodiment of the present invention. This embodiment is applied to a surgical clip.

The clip 13 shown in FIG. 7 is composed of a concave portion 14 and a convex portion 15 which are fitted to each other after being closed.
The clip 13 is made of a material having high viscoelasticity when not illuminated with light and low viscoelasticity when illuminated with light.

When the clip 13 thus constructed is used, for example, in a laparoscopic cholecystectomy, the clip 13 is darkly formed on the outer periphery of the cystic duct or the luminal organ 16 of the gallbladder artery by a known method, as shown in FIG. The clip 13 taken out from the place is hooked, and the concave portion 14 and the convex portion 15 are fitted together. Next, the one end 17 of the luminal organ 16 is cut with an electric knife or the like.

Since the tissues on the cut end surface of the end portion 17 are in close contact with each other, they are joined by the biological repair function over time. If the cut end surfaces are joined, the clip 13
It becomes useless. Therefore, the trocars 19A, 1 are attached to the abdominal wall 18.
9B is inserted, and the optical probe 2 is inserted through each internal conduit.
0, the suction probe 21 is inserted into the body cavity.

Then, as in the above-described embodiment, the optical probe 20 irradiates the clip 13 applied to the outer periphery of the luminal organ 16 such as the gallbladder duct or the gallbladder artery with the ultraviolet light. The irradiation of ultraviolet light reduces the viscoelasticity of the clip 13, making it unable to maintain its shape and fluidizing. Next, the fluidized clip 13 is sucked out of the body using the suction probe 21.

As with the above-described embodiments, the clip 13 of this embodiment can be easily taken out when it is no longer used after being placed in the body, because its viscosity is reduced by light irradiation to make it fluidized. is there. Further, although the surgical clip has been described as the clip 13 of the present embodiment, the clip 13 used in the digestive tract for the purpose of hemostasis also has the same effect.

Next, a fourth embodiment will be described. Figure 1
0 to 12 show an in-vivo indwelling device according to a fourth embodiment of the present invention. In this example, the ERB for bile discharge is used.
It is an application example to a D tube.

In the ERBD tube 22 shown in FIG. 10, a plurality of flaps 23 as a means for preventing movement after indwelling in the bile duct are formed in the peripheral wall and in the vicinity of both ends in a form of a cut in the tube wall thickness. There is. Also, ERBD
Side holes 24, 24 are provided at both the front and rear ends of the tube 22 so as to increase the bile draining function, in communication with the lumen of the tube.

The material of the ERBD tube 22 is made of a material having high viscosity when not irradiated with light and lower viscosity when irradiated with light, as in the first embodiment.

ERBD tube 22 constructed in this way
Is taken out from the dark place and placed in the stricture in the bile duct by an oral endoscopy by a known method.

When the lumen of the ERBD tube 22 is clogged with time and it is necessary to remove the ERBD tube 22, the optical probe 20 is moved to the ERBD via the endoscope 4 as shown in FIG.
Insert into the inner tube of the tube 22. Next, as shown in FIG. 12, the optical probe 20 emits ultraviolet light to irradiate the inner wall of the ERBD tube 22.

Since the ERBD tube 22 is made of a material whose viscosity is reduced by light irradiation as described above,
As shown in 2, the portion irradiated with light is fluidized. ER
By irradiating the entire circumference of the BD tube 22 with light, the whole is fluidized, and the fluidized material is discharged to the digestive tract via the duodenal papilla 26, so the ERBD tube 22
Will be removed from the bile duct 25.

Since the ERBD tube 22 of this embodiment is made of a material whose viscosity is reduced by irradiation with light, that is, when it is generated and needs to be removed from the bile duct, it can be irradiated with ultraviolet light from an optical probe. , Can be easily removed. Compared to the conventional method in which the snare is hooked on the flap and pulled, the tube can be easily removed from the bile duct without the risk of breaking the tube halfway.

By the way, "Intelligent Material" CMC Co., Ltd. issue (P180-181)
As described in (1), N-isopropylacrylamide 28 bound to the base material 27 is hydrated at a low temperature, has a structure in which a polymer chain is elongated, and exhibits hydrophilicity.
On the contrary, dehydration occurs at high temperature, and the polymer chain has a contracted structure and exhibits hydrophobicity. It is known that the cells 29, proteins and the like are less likely to adhere in the hydrophilic state, but are easily adsorbed to the hydrophobic surface. (See FIG. 25 above).

In this case, the critical temperature is 32 ° C., but N
-By chemically modifying isopropylacrylamide,
It is also possible to change the critical temperature.

13 to 16 show an in-vivo indwelling device according to the fifth embodiment of the present invention. In this embodiment, E
This is an application example to an RBD tube.

Similar to the fourth embodiment, the ERB shown in FIG.
The D tube 30 has a plurality of flaps 23 formed in the peripheral wall and in the vicinity of both ends thereof as a means for preventing movement after indwelling in the bile duct, with a cut in the tube wall thickness. In addition, at the front and rear ends of the ERBD tube 30, side holes 24, 24 are provided to increase the bile discharging function.
Are provided in communication with the tube lumen.

On the surface of the base material of the ERBD tube 30, a polymer chain 3 made of the above-mentioned N-isopropylacrylamide, the hydrophilicity and hydrophobicity of which change with temperature,
1 is provided by polymerization.

ERBD tube 30 constructed in this way
14, is orally projected from the channel hole of the endoscope 4 and pushed into the bile duct 25 via the papilla 26 by the pusher tube 32. This work is performed while discharging cold water from the pusher tube 32 toward the ERBD tube 30. The temperature of cold water is a critical temperature (32 ° C.) at which the polymer chains 31 show hydrophilicity.
The following temperatures are used.

When cold water below the critical temperature is discharged to the outer surface of the ERBD tube 30, the polymer chains 31 made of N-isopropylacrylamide bonded to the outer surface of the ERBD tube 30 are in a stretched state as described above. ,
It will be hydrophilic. Therefore, the insertion into the bile duct 25 can be easily performed.

Next, during the indwelling of the ERBD tube 30 in the bile duct 25, the polymer chains 31 bound to the outer surface of the ERBD tube 30 are in a contracted state due to the body temperature (37 ° C.) which is higher than the critical temperature and become hydrophobic. Become sex. As described above, it is known that cells tend to adhere in the hydrophobic state. Therefore, as shown in FIG. 15, the outer surface 33 of the ERBD tube 30 that is in close contact with the bile duct 25 joins with the cells of the bile duct 25, and the ERBD tube 30 body does not move from the indwelling position.

Next, a case where the inner tube of the ERBD tube 30 is clogged with time, that is, it is necessary to replace the inner tube, will be described. The overtube 34 is inserted endoscopically, and cold water below the critical temperature (32 ° C.) at which the polymer chains 31 exhibit hydrophilicity via the overtube 34 is supplied to the ERBD tube 3.
It emits toward 0. By releasing cold water, ERB
The polymer chain 31 made of N-isopropylacrylamide bonded to the outer surface of the D tube 30 is in an expanded state as described above, and exhibits hydrophilicity. Therefore, as shown in FIG. 16, the cells of the bile duct 25 and the ERBD tube 3
The outer surface 33 of 0 is not joined. Then, with the cold water discharged from the overtube 34, the snare 35 is further inserted, hooked on the flap 23, and pulled out. E
The RBD tube 30 is endoscopically removed.

In the ERBD tube 30 of this embodiment, a polymer chain whose hydrophilicity and hydrophobicity change depending on temperature is bonded to the outer surface of the ERBD tube 30. Therefore, when the ERBD tube 30 is inserted into the bile duct, it is hydrophilic by releasing cold water. It can be easily inserted. Also,
At the time of indwelling, because it is above the critical temperature due to body temperature,
It becomes hydrophobic and will not fall off or stray from the indwelling position.

On the other hand, when the ERBD tube 30 is withdrawn, the surface becomes hydrophilic by withdrawing it while releasing cold water again, so that the ERBD tube 30 can be easily removed.

FIG. 17 and FIG. 18 show an in-vivo indwelling device according to the sixth embodiment of the present invention. The in-vivo indwelling device of this example is applied to a fallopian tube obturator.

The obturator 36 shown in FIG. 17 is made of an elastic material such as silicone and is integrally formed into a substantially spherical shape. further,
On the outer surface of the obturator 36, a polymer chain 31 which is made of N-isopropylacrylamide described above and whose hydrophilicity / hydrophobicity changes depending on temperature is attached.

A method of using the obturator 36 having the above structure will be described. The obturator 36 is an overtube 34.
The obturator 36 is grasped by the grasping forceps 2 which is inserted via the, and is inserted into the oviduct 3 endoscopically in this state. This operation is performed while discharging cold water from the hand side toward the obturator 36 through the overtube 34.
The temperature of cold water is set to a temperature equal to or lower than the critical temperature (32 ° C.) at which the polymer chain 31 exhibits hydrophilicity.

When cold water below the critical temperature is discharged to the outer surface of the obturator 36, the polymer chain 31 made of N-isopropylacrylamide bonded to the outer surface of the obturator 36 becomes in the stretched state as described above and becomes hydrophilic. Will show sex.
Therefore, the insertion into the oviduct 3 can be easily performed.

Next, while the obturator 36 is placed in the oviduct 3,
The polymer chains 31 bonded to the outer surface of the obturator 36 are in a contracted state due to the body temperature (37 ° C.) which is higher than the critical temperature, and become hydrophobic. As mentioned above, cells tend to adhere in the hydrophobic state. Therefore, the obturator 36 that is in close contact with the oviduct 3
The outer surface of the obturator joins with the cells on the inner wall of the oviduct 3 and the main body of the obturator 36 does not move from the indwelling position to maintain the contraception effect.

Next, the patient desires to become pregnant again and the obturator 36
The method of removing the will be described. As shown in FIG.
The overtube 34 is inserted into the fallopian tube 3, and cold water having a critical temperature (32 ° C.) or lower is again discharged from the hand side toward the obturator 36. The release of cold water causes the polymer chains 31 bonded to the outer surface of the obturator 36 to be in an expanded state and exhibit hydrophilicity.

In the above state, the grasping forceps 2 can be inserted through the overtube 34 and the obturator 36 can be grasped to be easily removed, so that the oviduct 3 is opened.

The obturator 36 of this embodiment has an outer surface
Since a polymer chain whose hydrophilicity / hydrophobicity changes depending on temperature is bonded, it becomes hydrophilic by injecting cold water below the critical temperature, and insertion / removal into / from the oviduct 3 can be easily performed.
Further, when the obturator 36 is placed in the fallopian tube, the obturator 36 becomes more than the critical temperature at the body temperature and becomes hydrophobic, so that the obturator 36 is bonded to the cells on the inner wall of the fallopian tube and is not likely to move or drop from the indwelling portion.

Next, a seventh embodiment will be described. Figure 1
9 to 20 are views according to a seventh embodiment of the present invention. This embodiment is applied to a surgical clip.

A clip 37 shown in FIG. 19 has a concave portion 14 and a convex portion 15 which are fitted to each other after being closed, and is integrally made of a resin material. Further, on the inner surfaces of the concave portion 14 and the convex portion 15 of the clip 37, a polymer chain 31 made of N-isopropylacrylamide whose hydrophilicity and hydrophobicity change depending on the above-mentioned temperature is provided so as to be bonded.

When the clip 37 thus constructed is used for laparoscopic cholecystectomy, for example, a concave portion 14 and a convex portion 15 are formed on the outer periphery of the cystic duct or the luminal organ 16 of the gallbladder artery by a known method. Apply and block. Then, one end 17 of the luminal organ 16 is cut with an electric knife or the like.

During the indwelling in the body, the polymer chain 31 provided on the inner surface of the clip 37 contracts to a critical temperature or higher due to the body temperature (37 ° C.) and is in a hydrophobic state. Therefore, as described above, it bonds with the cells of the luminal organ 16 and does not move from the indwelling site.

By the way, when the cut one end portion 17 is joined and closed by the biological repair function over time, the clip 37 is formed.
Becomes useless. Then, through the abdominal wall 18, the trocar 1
9A and 19B are again inserted into the body, and the grasping forceps 2 and the sheath 38 are inserted into the body cavity through the inner tube of each trocar. Then, through the sheath 38, the critical temperature (32 ° C.)
The following cold water is discharged to the clip 37. When cold water is released, the polymer chains 31 on the inner surface of the clip 37 expand and become hydrophilic, and are separated from the cells of the luminal organ 16. Then, the grasping forceps 2 is operated to remove the clip 37 from the luminal organ 16.

The clip 37 of this embodiment has a polymer chain 31 whose hydrophilicity / hydrophobicity changes depending on temperature, bound to the inner surface of the clip 37. Therefore, the clip 37 becomes hydrophobic during indwelling in the body and adheres to the luminal organ and falls off. There is no risk of movement. Further, when the clip 37 is no longer required for indwelling, it becomes hydrophilic by applying cold water, and can be easily peeled from the tissue and removed.

Although the surgical clip has been described in the present embodiment, the same effect can be obtained even if it is used in the digestive tract for the purpose of hemostasis. That is, the application of the surgical clip is not limited to the above example.

Next, an eighth embodiment will be described. ◎ FIGS. 21 to 23 show the invention according to the eighth embodiment of the present invention. This embodiment is an application example to biopsy forceps.

Tip cup 4 of biopsy forceps 39 shown in FIG.
0 has a resin layer coated on its inner surface,
Further, the polymer chain 31 made of N-isopropylacrylamide described above is bonded to the outer surface of the resin layer.

The biopsy forceps 39 thus constructed is inserted into the biopsy forceps 39 through the endoscope channel, and the tip cup 4 is inserted.
The target tissue in the body is grasped and collected by the inside of 0.
In this case, the polymer chains on the inner surface of the tip cup 40 of the biopsy forceps 39 contract and become hydrophobic due to the body temperature (37 ° C.) that is equal to or higher than the critical temperature. Therefore, it is easily joined to the tissue to be biopsied, and is reliably taken into the tip cup 40, and there is no risk of falling off.

Next, in order to collect the collected tissue from the tip cup 40, as shown in FIG. 22, the biopsy forceps 39 is immersed in a petri dish 41 containing cold water below the critical temperature.

By immersing in cold water, the polymer chains 31 attached to the inner surface of the tip cup 40 expand and show hydrophilicity. Then, as described above, the bond with the tissue is weakened, so that the biopsied tissue 42 is separated from the inner surface of the distal end cup 40 and floats in cold water. The biopsy tissue 42 can be collected by filtering this cold water.

The biopsy forceps 39 of this embodiment is the tip cup 4
A polymer chain whose hydrophilicity and hydrophobicity change depending on temperature is bonded to the inner surface of 0. Therefore, the biopsy forceps 39 can surely take the tissue into the distal end cup 40 during the biopsy, and can also be easily collected and removed by immersing it in cold water.

It should be noted that, instead of the biopsy forceps 39 of this embodiment, providing the above-mentioned polymer chain on the brush portion 44 of the cytodiagnosis brush 43 shown in FIG. 23 has the same effect.

[0079]

EFFECTS OF THE INVENTION The in-vivo indwelling device of the present invention has an effect that it can be arbitrarily taken out of the body by a simple operation when it is no longer needed after being left in the living body.

[Brief description of drawings]

1 to 3 relate to a first embodiment, and FIG. 1 is an explanatory view showing the placement of an obturator.

FIG. 2 is an explanatory view showing an indwelling state and recovery of the obturator.

FIG. 3 is an explanatory view showing the collection of the obturator.

FIG. 4 is a sectional view of an obturator according to a modification of the first embodiment.

5 and 6 relate to the second embodiment, and FIG. 5 is an explanatory view showing the placement of a blood vessel splint.

FIG. 6 is an explanatory diagram showing collection of blood vessel splints.

7 to 9 relate to a third embodiment, and FIG. 7 is a perspective view of a surgical clip.

FIG. 8 is an explanatory view showing an indwelling state of the surgical clip.

FIG. 9 is an explanatory view showing recovery of a surgical clip.

10 to 12 relate to the fourth embodiment, and FIG. 10 is a side sectional view of an ERBD tube for bile drainage.

FIG. 11 is an explanatory diagram showing an indwelling state and recovery of an ERBD tube.

FIG. 12 is an explanatory diagram showing recovery of ERBD tubes.

13 to 16 relate to a fifth embodiment, and
The sectional side view of an RBD tube.

FIG. 14 is an explanatory diagram showing a mounted and indwelling state of an ERBD tube.

FIG. 15 is an explanatory view showing an indwelling state of the ERBD tube.

FIG. 16 is an explanatory diagram showing recovery of ERBD tubes.

17 and 18 relate to a sixth embodiment, and FIG.
7 is an explanatory view showing the placement of the fallopian tube obturator.

FIG. 18 is an explanatory view showing the indwelling state and collection of the fallopian tube obturator.

19 to 20 relate to a seventh embodiment, and FIG. 19 is a perspective view of a surgical clip.

FIG. 20 is an explanatory view showing recovery of a surgical clip.

21 to 23 relate to the eighth embodiment, and FIG. 21 is a perspective view of a biopsy forceps.

FIG. 22 is an explanatory diagram showing the recovery of biological tissues collected by biopsy forceps.

FIG. 23 is a side view of the cytodiagnosis brush.

FIG. 24 is an explanatory diagram of materials.

FIG. 25 is an explanatory diagram of materials.

[Explanation of Codes] 1 ... Obturator 2 ... Grasping forceps 3 ... Fallopian tube 4 ... Endoscope 5 ... Light guide 6 ... Channel hole 7 ... Suction probe

Claims (1)

[Claims] 1. An in-vivo indwelling device, which is made of a material that has high viscoelasticity when not irradiated with light and is fluidized by decreasing viscoelasticity when irradiated with light.