JPH06504185A - Ｃ・ｋｉｔ受容体に対するリガンド及びその使用法 - Google Patents
Ｃ・ｋｉｔ受容体に対するリガンド及びその使用法Info
- Publication number
- JPH06504185A JPH06504185A JP3515137A JP51513791A JPH06504185A JP H06504185 A JPH06504185 A JP H06504185A JP 3515137 A JP3515137 A JP 3515137A JP 51513791 A JP51513791 A JP 51513791A JP H06504185 A JPH06504185 A JP H06504185A
- Authority
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- Prior art keywords
- cells
- pharmaceutical composition
- kit
- cell
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Plant Pathology (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57348390A | 1990-08-27 | 1990-08-27 | |
| US573,483 | 1990-08-27 | ||
| US594,306 | 1990-10-05 | ||
| US07/594,306 US20030125519A1 (en) | 1990-08-27 | 1990-10-05 | Ligand for the c-kit receptor and methods of use thereof |
| PCT/US1991/006130 WO1992003459A1 (en) | 1990-08-27 | 1991-08-27 | LIGAND FOR THE c-KIT RECEPTOR AND METHODS OF USE THEREOF |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH06504185A true JPH06504185A (ja) | 1994-05-19 |
Family
ID=27076120
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3515137A Pending JPH06504185A (ja) | 1990-08-27 | 1991-08-27 | Ｃ・ｋｉｔ受容体に対するリガンド及びその使用法 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US20030125519A1 (enExample) |
| EP (1) | EP0546054A1 (enExample) |
| JP (1) | JPH06504185A (enExample) |
| KR (1) | KR930703339A (enExample) |
| AU (1) | AU654502B2 (enExample) |
| CA (1) | CA2090469A1 (enExample) |
| HU (1) | HUT64368A (enExample) |
| WO (1) | WO1992003459A1 (enExample) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6852313B1 (en) | 1989-10-16 | 2005-02-08 | Amgen Inc. | Method of stimulating growth of melanocyte cells by administering stem cell factor |
| US7144731B2 (en) * | 1989-10-16 | 2006-12-05 | Amgen Inc. | SCF antibody compositions and methods of using the same |
| JP2657113B2 (ja) * | 1989-10-16 | 1997-09-24 | アムジエン・インコーポレーテツド | 幹細胞因子 |
| US20040181044A1 (en) * | 1989-10-16 | 2004-09-16 | Zsebo Krisztina M. | Method of stimulating growth of epithelial cells by administering stem cell factor |
| US20030125519A1 (en) | 1990-08-27 | 2003-07-03 | Peter Besmer | Ligand for the c-kit receptor and methods of use thereof |
| US20050276784A1 (en) * | 1990-08-27 | 2005-12-15 | Solan-Kettering Institute For Cancer Research | Ligand for the c-kit receptor and methods of use thereof |
| DK0639979T3 (da) * | 1992-04-23 | 2002-12-02 | Sloan Kettering Inst Cancer | Ligand for c-kit-receptoren og fremgangsmåde til anvendelse heraf |
| US5981569A (en) * | 1992-11-13 | 1999-11-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Substituted phenylacrylonitrile compounds and compositions thereof for the treatment of disease |
| US5763441A (en) * | 1992-11-13 | 1998-06-09 | Sugen, Inc. | Compounds for the treatment of disorders related to vasculogenesis and/or angiogenesis |
| US5792771A (en) * | 1992-11-13 | 1998-08-11 | Sugen, Inc. | Quinazoline compounds and compositions thereof for the treatment of disease |
| CN1173991C (zh) * | 1992-11-13 | 2004-11-03 | 马克斯普朗克科学促进协会 | 作为血管内皮生长因子受体的f1k-1 |
| US6177401B1 (en) | 1992-11-13 | 2001-01-23 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften | Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis |
| US5712395A (en) * | 1992-11-13 | 1998-01-27 | Yissum Research Development Corp. | Compounds for the treatment of disorders related to vasculogenesis and/or angiogenesis |
| US6872699B2 (en) | 1992-11-13 | 2005-03-29 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften, E.V. | Truncated Flk-1 receptor protein, methods of use and a recombinant vector containing a nucleotide encoding the truncated Flk-1 protein |
| WO1994019463A2 (en) * | 1993-02-16 | 1994-09-01 | Auckland Uniservices Limited | Developmental tyrosine kinases and their ligands |
| US5525708A (en) * | 1994-03-28 | 1996-06-11 | Cytomed, Inc. | Covalent dimer of kit ligand |
| US6024734A (en) * | 1994-03-31 | 2000-02-15 | Brewitt; Barbara A. | Treatment methods using homeopathic preparations of growth factors |
| GB9515839D0 (en) * | 1995-08-02 | 1995-10-04 | Q One Biotech Ltd | Feline stem cell factor |
| US5885962A (en) * | 1996-04-05 | 1999-03-23 | Amgen Inc. | Stem cell factor analog compositions and method |
| US6734338B1 (en) | 1997-11-14 | 2004-05-11 | Cedars-Sinai Medical Center | Transfection, storage and transfer of male germ cells for generation of transgenic species and genetic therapies |
| CA2309904A1 (en) | 1997-11-14 | 1999-05-27 | Cedars-Sinai Medical Center | Transfection and transfer of male germ cells for generation of transgenic species |
| US7294755B1 (en) | 1997-11-14 | 2007-11-13 | Cedars-Sinai Medical Center | Genetic modification of male germ cells for generation of transgenic species and genetic therapies |
| JP2003525581A (ja) * | 1998-11-13 | 2003-09-02 | セダーシナイ メディカル センター | 脊椎動物精巣の細胞減失（ｄｅｐｏｐｕｌａｔｉｎｇ）方法およびトランスジェニック種の作製方法 |
| AU3563499A (en) * | 1998-11-13 | 2000-06-05 | Cedars-Sinai Medical Center | Transfection of male germ cells for generation of selectable transgenic stem cells |
| FR2853663B1 (fr) * | 2003-04-14 | 2007-08-31 | Aventis Pharma Sa | Procede d'obtention de lignees de mastocytes a partir de tissus de porcs et procede de production de molecules de type heparine |
| US20060153799A1 (en) | 2004-11-05 | 2006-07-13 | Northwestern University | Use of SCF and G-CSF in the treatment of cerebral ischemia and neurological disorders |
| EP1877547B1 (en) | 2005-05-04 | 2012-08-08 | Commonwealth Scientific and Industrial Research Organisation | Selecting, culturing and creating lineage committed hematopoietic stem cells |
| AU2006315601A1 (en) * | 2005-11-14 | 2007-05-24 | Enterprise Partners Venture Capital | Stem cell factor therapy for tissue injury |
| WO2007149493A2 (en) * | 2006-06-22 | 2007-12-27 | Immugen Inc | Restoration of hearing loss |
| CA2677273A1 (en) * | 2007-02-06 | 2008-08-14 | Tai-June Yoo | Use of a composition comprising a cytokine encoding nucleic acid for treating alzheimer's disease |
| DK2668210T3 (da) | 2011-01-26 | 2020-08-24 | Celldex Therapeutics Inc | Anti-kit antistoffer og anvendelser deraf |
| KR101384360B1 (ko) * | 2012-05-04 | 2014-04-14 | 아주대학교산학협력단 | Ｓｃｆ 또는 이의 수용체를 억제하는 물질을 포함하는 혈관 투과성 관련 질환의 치료 또는 예방용 조성물 |
| WO2014018625A1 (en) | 2012-07-25 | 2014-01-30 | Kolltan Pharmaceuticals, Inc. | Anti-kit antibodies and uses thereof |
| CN113975386A (zh) | 2014-05-23 | 2022-01-28 | 塞尔德克斯医疗公司 | 嗜酸性粒细胞或肥大细胞相关病症的治疗 |
| IL294032A (en) | 2019-12-24 | 2022-08-01 | Carna Biosciences Inc | Compounds that regulate diacylglycerol kinase |
| EP4103285A2 (en) | 2020-02-14 | 2022-12-21 | Jounce Therapeutics, Inc. | Antibodies and fusion proteins that bind to ccr8 and uses thereof |
| CN117355531A (zh) | 2021-06-23 | 2024-01-05 | 吉利德科学公司 | 二酰基甘油激酶调节化合物 |
| EP4359413A1 (en) | 2021-06-23 | 2024-05-01 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
| CN117377671A (zh) | 2021-06-23 | 2024-01-09 | 吉利德科学公司 | 二酰基甘油激酶调节化合物 |
| CA3220923A1 (en) | 2021-06-23 | 2022-12-29 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
| JP2024539252A (ja) | 2021-10-28 | 2024-10-28 | ギリアード サイエンシーズ， インコーポレイテッド | ピリジジン－３（２ｈ）－オン誘導体 |
| PE20241186A1 (es) | 2021-10-29 | 2024-06-03 | Gilead Sciences Inc | Compuestos de cd73 |
| JP2024546851A (ja) | 2021-12-22 | 2024-12-26 | ギリアード サイエンシーズ， インコーポレイテッド | Ｉｋａｒｏｓジンクフィンガーファミリー分解剤及びその使用 |
| CA3237577A1 (en) | 2021-12-22 | 2023-06-29 | Gilead Sciences, Inc. | Ikaros zinc finger family degraders and uses thereof |
| TW202340168A (zh) | 2022-01-28 | 2023-10-16 | 美商基利科學股份有限公司 | Ｐａｒｐ７抑制劑 |
| PL4245756T3 (pl) | 2022-03-17 | 2025-02-17 | Gilead Sciences, Inc. | Środki degradujące palec cynkowy z rodziny ikaros i ich zastosowania |
| CA3249472A1 (en) | 2022-04-21 | 2023-10-26 | Gilead Sciences, Inc. | KIRSTEN G12D RAT SARCOMA VIRUS MODULATOR COMPOUNDS |
| AU2023298558A1 (en) | 2022-07-01 | 2024-12-19 | Gilead Sciences, Inc. | Cd73 compounds |
| CN120225509A (zh) | 2022-12-22 | 2025-06-27 | 吉利德科学公司 | Prmt5抑制剂及其用途 |
| CN120882725A (zh) | 2023-04-11 | 2025-10-31 | 吉利德科学公司 | Kras调节化合物 |
| KR20250175331A (ko) | 2023-04-21 | 2025-12-16 | 길리애드 사이언시즈, 인코포레이티드 | Prmt5 억제제 및 이의 용도 |
| AU2024306338A1 (en) | 2023-06-30 | 2026-01-08 | Gilead Sciences, Inc. | Kras modulating compounds |
| WO2025024811A1 (en) | 2023-07-26 | 2025-01-30 | Gilead Sciences, Inc. | Parp7 inhibitors |
| US20250066328A1 (en) | 2023-07-26 | 2025-02-27 | Gilead Sciences, Inc. | Parp7 inhibitors |
| EP4516807A1 (en) | 2023-08-28 | 2025-03-05 | Consorcio Centro de Investigación Biomédica en Red | Compositions for use in a method of providing improved hematopoietic stem cell engraftment |
| US20250109147A1 (en) | 2023-09-08 | 2025-04-03 | Gilead Sciences, Inc. | Kras g12d modulating compounds |
| US20250101042A1 (en) | 2023-09-08 | 2025-03-27 | Gilead Sciences, Inc. | Kras g12d modulating compounds |
| US20250154172A1 (en) | 2023-11-03 | 2025-05-15 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
| US20250230168A1 (en) | 2023-12-22 | 2025-07-17 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |
| WO2025245003A1 (en) | 2024-05-21 | 2025-11-27 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5399493A (en) | 1989-06-15 | 1995-03-21 | The Regents Of The University Of Michigan | Methods and compositions for the optimization of human hematopoietic progenitor cell cultures |
| DE69034258D1 (de) * | 1989-10-16 | 2008-09-18 | Amgen Inc | Stamzellfaktor |
| WO1991014767A1 (en) | 1990-03-23 | 1991-10-03 | Ludwig Institute For Cancer Research | Method for enhanced growth and proliferation of mast cells |
| WO1992000376A1 (en) * | 1990-06-25 | 1992-01-09 | Immunex Corporation | Mast cell growth factor |
| US20030125519A1 (en) | 1990-08-27 | 2003-07-03 | Peter Besmer | Ligand for the c-kit receptor and methods of use thereof |
| US5767074A (en) | 1990-08-27 | 1998-06-16 | Sloan-Kettering Institute For Cancer Research | Compositions of soluble C-kit ligand and hematopoietic factors |
| AU9028791A (en) | 1990-10-05 | 1992-04-28 | President And Fellows Of Harvard College | Detection and isolation of ligands |
| US5409825A (en) | 1991-04-09 | 1995-04-25 | Indiana University Foundation | Expansion of human hematopoietic progenitor cells in a liquid medium |
| US5199942A (en) | 1991-06-07 | 1993-04-06 | Immunex Corporation | Method for improving autologous transplantation |
| US6001803A (en) | 1992-04-23 | 1999-12-14 | Sloan-Kettering Institute For Cancer Research | Composition of c-kit ligand, GM-CSF, and TNF-α and method of use |
-
1990
- 1990-10-05 US US07/594,306 patent/US20030125519A1/en not_active Abandoned
-
1991
- 1991-08-27 KR KR1019930700578A patent/KR930703339A/ko not_active Ceased
- 1991-08-27 JP JP3515137A patent/JPH06504185A/ja active Pending
- 1991-08-27 CA CA002090469A patent/CA2090469A1/en not_active Abandoned
- 1991-08-27 EP EP91916054A patent/EP0546054A1/en not_active Withdrawn
- 1991-08-27 HU HU9300541A patent/HUT64368A/hu unknown
- 1991-08-27 WO PCT/US1991/006130 patent/WO1992003459A1/en not_active Ceased
- 1991-08-27 AU AU85106/91A patent/AU654502B2/en not_active Withdrawn - After Issue
-
1995
- 1995-06-07 US US08/478,414 patent/US5935565A/en not_active Expired - Lifetime
-
1999
- 1999-08-10 US US09/371,261 patent/US6403559B1/en not_active Expired - Fee Related
-
2002
- 2002-04-24 US US10/132,345 patent/US20030103937A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| HUT64368A (en) | 1993-12-28 |
| HU9300541D0 (en) | 1993-05-28 |
| US5935565A (en) | 1999-08-10 |
| AU654502B2 (en) | 1994-11-10 |
| US20030125519A1 (en) | 2003-07-03 |
| US6403559B1 (en) | 2002-06-11 |
| AU8510691A (en) | 1992-03-17 |
| CA2090469A1 (en) | 1992-02-28 |
| WO1992003459A1 (en) | 1992-03-05 |
| EP0546054A1 (en) | 1993-06-16 |
| KR930703339A (ko) | 1993-11-29 |
| EP0546054A4 (enExample) | 1994-04-27 |
| US20030103937A1 (en) | 2003-06-05 |
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