JPH0631878A - Packing body of water-soluble drug - Google Patents

Abstract

PURPOSE:To prevent moisture absorption of a water-soluble film and a drug in a preservation state and to easily remove a moistureproof film at a time of use by bonding the moistureproof film to a PVA film and forming the recessed parts for housing in a manner that the PVA film side becomes the internal face. CONSTITUTION:A laminated film 4 is constituted by laminating a PVA film 2 and a moistureproof film 3. A plurality of recessed parts 5 for housing are so arranged and formed in a zigzag type on the laminated film 4 that the PVA film 2 side becomes the internal face. A cover film 6 is provided in the PVA film 2 side so as to close the recessed parts 5 for housing. Further a pressure-sensitive adhesive layer 7 is so formed in the cover film 6 that a packing body 1 is conveniently stuck to a planter P for gardening. A release paper 8 is provided in the pressure-sensitive adhesive layer 7 in a nonusing state.

Description

Detailed Description of the Invention

[0001]

[Object of the Invention]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a packaging material for holding water-soluble chemicals such as fertilizers for gardening, pest repellents and surface treatment agents for concrete structures.

[0002]

BACKGROUND OF THE INVENTION A method of packaging various water-soluble drugs in a water-soluble film and dissolving the film with water such as rainwater to expose and dissolve the water-soluble drug has been conventionally known. However, the water-soluble film is affected by the humidity of the storage environment, and when it absorbs moisture and reaches an equilibrium moisture content of 20% and 60% RH of 12 to 13%, the film itself becomes flexible and the strength decreases.
Further, when the film absorbs moisture, the contents also absorb moisture at the same time, which may change the shape and properties and reduce the commercial value. Therefore, in order to prevent such a problem from occurring, a conventional packaging body of this type requires a moisture-proof outer bag, which causes an increase in the number of packaging steps and a high cost.

On the other hand, in order to distribute fertilizer, powdered medicine and the like into a sheet having a constant area at a constant interval, a lot of work and labor are required for the filling method, and it is not always possible to realize a rational work. It didn't come.

[0004]

[Technical Items Attempted to Develop] The present invention has been made in view of such a background. It is possible to prevent moisture absorption of a water-soluble film or a drug in a storage state, and easily remove the moisture-proof film at the time of use. This is an attempt to develop a package of a water-soluble drug made possible.

[0005]

[Constitution of the invention]

[Means for Achieving the Object] That is, the water-soluble drug package according to the first invention of the present application is a laminated film in which a polyvinyl alcohol film and a moisture-proof film are peelably adhered to each other to form a laminated film. A storage recess is formed so that the side faces the inner surface, and a cover film is provided on the polyvinyl alcohol film side with the water-soluble drug stored in the storage recess.

In addition to the above requirements, the polyvinyl alcohol film has a saponification degree of 75 to 99 mol%, and the moisture-proof film has a water vapor transmission rate of 100 g / m ^2.・ 24 hours (40
C., 90% RH) or less).

Further, in the water-soluble drug package according to the third invention of the present application, in addition to the above requirements, the cover film is adhered to the polyvinyl alcohol film by heat fusion or pressure-sensitive adhesive. It is characterized by being formed.

Furthermore, in addition to the above requirements, the water-soluble drug package according to the fourth invention of the present application has a part of the laminated interface between the polyvinyl alcohol film and the moisture-proof film at the end of the laminated film. It is characterized in that the release agent is applied to the to form the knob portion. The above objects are achieved by these inventions.

The present invention will be specifically described below based on the illustrated embodiments. FIG. 1 shows a state in which a horticultural fertilizer S is contained in a water-soluble drug package 1 of the present invention and is attached to the inside of a horticultural planter P as an example for use. As shown in FIG. 2, the package 1 includes a laminated film 4 formed by laminating a polyvinyl alcohol film 2 and a moisture-proof film 3 and a plurality of storage recesses 5 so that the polyvinyl alcohol film 2 side is an inner surface. As shown in FIG. 4, a zigzag arrangement is formed, and a cover film 6 is provided on the polyvinyl alcohol film 2 side so as to close the storage recess 5. An adhesive layer 7 is formed on the cover film 6 so as to conveniently attach the package 1 to the gardening planter P, and the adhesive layer 7 is provided with a release paper 8 when not in use.

The constituent elements of such a package 1 will be specifically described. First, the polyvinyl alcohol film 2 has a saponification degree of 75 to 99 mol%, but considering the solubility in water, 87 to 89 mol% is used. It is suitable. The thickness depends on the drawing ratio, such as the molding depth when molding the storage recess 5, but can be used in the range of 20 to 100 μm.

The moisture-proof film 3 is provided to protect the polyvinyl alcohol film 2 from moisture, and its moisture permeability is 100 g / m ² · 24 hrs (40 ° C, 90% RH).
The following is desired. As such a synthetic resin, polyethylene, polypropylene, polyester, polyamide, polystyrene, polycarbonate, polyvinyl chloride, polyvinylidene chloride or the like can be applied, but the thickness is determined by the water vapor permeability of each synthetic resin.

For example, a thickness of 25 μm and a water vapor transmission rate of 280 g / m ² · 24 hr
Polyamide of s (40 ° C, 90% RH) has a moisture permeability of 100g / m ² · 24hrs (40 ° C, 90% RH) at a thickness of 70μ, and a thickness of 70μ or more is required for this application. Polycarbonate with a water vapor transmission rate of 80g / m ² · 24hrs (40 ° C, 90% RH) has a thickness of 20μ and a water vapor transmission rate of 100g / m ² · 24hrs (40 ° C, 90% R).
H), which requires a thickness of 20 μm or more. The thickness of the moisture-proof film 3 is set in consideration of not only the polyvinyl alcohol film 2 but also the hygroscopicity of the water-soluble drug put in the storage recess 5.

The laminated state of the polyvinyl alcohol film 2 and the moisture-proof film 3 is in a state where it can be easily peeled off. Polyvinyl alcohol film 2 and water vapor transmission rate 100
Regarding the method of laminating the moisture-proof film 3 of g / m ² · 24hrs (40 ° C, 90% RH) or less with the removable adhesive force, it is said to be a thermal laminate in which two films are heated and pressed to bond them together. A method or a method called extrusion lamination in which two or more kinds of synthetic resins, which are heated and melted on the polyvinyl alcohol film 2, are laminated in a film form or by coextrusion,
Further, there is a method called dry lamination in which an adhesive is applied to one of the two films and they are heated and pressed against each other.
By either method, it is easy to obtain a removable adhesive force depending on the heating conditions, the type of adhesive used, and the like. It should be noted that the adhesive force with which re-peeling can be performed without any problem is
A width of 0 to 80 g / 15 mm is suitable.

When the polyvinyl alcohol film 2 and the moisture-proof film 3 are peeled off, the laminated film 4 has an edge portion at the laminated interface between the polyvinyl alcohol film 2 and the moisture-proof film 3 so that they can be easily peeled off. Alternatively, the release agent may be partially applied in advance and the portion may be used as the knob portion 9. Examples of the release agent include silicone resin, aminoalkyd resin, polyester resin, polyamide resin, and cellulose resin. As another method of forming the knob portion 9, when the polyvinyl alcohol film 2 and the moisture-proof film 3 are bonded together with an adhesive or an adhesive resin, the non-adhesive portion may be left as the knob portion 9. .

Next, the cover film 6 is made of polyvinyl alcohol or polyethylene vinyl alcohol as a seal layer, and is a heat-sealed fusion-resistant composite film. Here, the moisture-proof treatment may be, for example, a method of forming a moisture-proof layer by coating with vinylidene chloride or the like, or laminating polyethylene, polypropylene, polyester, polyamide or the like by extrusion laminating, dry laminating or the like.

If a pressure-sensitive adhesive coated sheet is used, it is possible to carry out pressure bonding at room temperature. As the pressure-sensitive adhesive coated sheet, a pressure-sensitive adhesive coated on both sides of a moisture-proof synthetic resin film, a pressure-sensitive adhesive coated on only one side, and further heat fusion bonding A combination of a film and a pressure-sensitive adhesive applied on one surface and a composite of a synthetic resin such as polyethylene vinyl alcohol which can be heat-bonded to a polyvinyl alcohol film on the other surface can be used.

Next, the storage recess 5 will be described. The storage recess 5 can be formed by either vacuum forming or pressure forming of the laminated film 4, but the heating temperature and forming conditions differ depending on the type of the moisture-proof film 3. Further, from the viewpoint of ease of molding, it is desirable that the laminated film 4 is unstretched, but even a stretched laminated product or the like can be molded if the storage recess 5 has a shallow molding depth.

Further, the water-soluble chemical to be put into the storage recess 5 is the fertilizer S for gardening in this embodiment, but in addition to this, various agricultural chemicals,
A detergent, a pigment, a surface treatment agent, etc. may be added, and in particular, a salt damage inhibitor which is a surface treatment agent for concrete, a surface active agent,
It is thought that effective applications can be developed by adding waterproofing agents, coloring agents, non-slip agents, alkali neutralizing agents, curing agents and the like. It should be noted that it is not necessary to put the same type of water-soluble drug in all the storage recesses 5, but it is possible to put different types of water-soluble drugs or put mutually reactive drugs in different storage recesses 5. You can also Of course, it is also possible to put a medicine that is not water-soluble in the storage recess 5.

The usage of the package 1 in which the water-soluble drug S is housed is not limited to the method of sticking by the adhesive force as in the above embodiment, and the adhesive as shown in FIG. 10 is attached, or a magnet 11 is put in some of the storage recesses 5 as shown in FIG. 5 (b) to be attracted to the magnetic body 12 by magnetic force, or as shown in FIG. 5 (c), with a thumbtack 13 or the like. Various modes such as fastening or simply laying on the ground 14 as shown in FIG. 6 can be adopted. Further, the arrangement form of the storage recesses 5 is also free according to the intended use, and the broken lines 15 which can be easily cut between the storage recesses 5 as shown in FIG. You can put it in.

[0020]

In the present invention, since the polyvinyl alcohol film is peelably covered with the moisture-proof film,
The polyvinyl alcohol film is prevented from absorbing moisture during storage, and the moisture-proof film can be easily peeled off before use. In addition, since the storage recess is formed, even if the water-soluble drug is solid or powdery, the position of the drug is not displaced or biased in the package, and the uniformity of the water-soluble drug can be maintained.

[0021]

[Example] Toray Synthetic Film Co., Ltd. unstretched polypropylene (Trefan NO3401) 100 μm was coated with a colored silicone resin in a thickness of 2 μm, and a polyvinyl alcohol film manufactured by Tokyo Cellophane Paper Co., Ltd. was applied. 30μ
It was thick and dry laminated using a polyester adhesive.

The coating amount of the adhesive is 0.5 g / m ^{2 of} solid content.
The adhesive strength was 100 g / 15 mm width, and peeling was easy. The moisture vapor transmission rate of this laminated product is 3 g / m ²
・ It was 24hrs (40 ℃, 90% RH). This laminated product is
The mixture was heated at ℃ for 7 seconds and vacuum-molded so that the polyvinyl alcohol film was on the inner surface. The molding die was 25 mmΦ, the molding depth was 15 mm, and the drawing ratio was 0.6, but the molding was easy. The molding parts were arranged at 60 mm intervals from each other, and the recesses obtained by molding were filled with ortran granules, which is a pest repellent for gardening, and a cover film was provided.

This cover film is a sheet obtained by coating a pressure-sensitive adhesive on both sides of a stretched polypropylene (Trefan NO2545) film 50μ manufactured by Toray Industries, Inc.
With the silicone release paper on one side, the other side was used and pressure-bonded to the laminated product molded at room temperature. The moisture permeability of the cover film was 2.5 g / m ² · 24 hrs (40 ° C, 90% RH). On the other hand, as a comparative example, orthotran granules were piled up on the polyvinyl alcohol film alone at intervals of about 60 mm and pressure-bonded using the same cover film.

[0024]

EFFECTS OF THE INVENTION The orthotran granules packaged by the laminated product having the moisture-proof layer of the above-mentioned examples show little moisture absorption even in the atmosphere of 40 ° C. and 80% RH, and in the drop test on concrete. However, there was no problem at all. The silicone release paper was peeled off, the pressure-sensitive adhesive was exposed, and the pressure-sensitive adhesive was attached to the inside of the gardening planter. Then, the peeling opening of the molded film was pinched, and the unstretched polypropylene film was peeled off. After that, a culture soil was added, roses were planted and watered. For 2 months, no turnip worms that tend to parasitize roses were found at all, and when the packaging sheet was dug out, the polyvinyl alcohol film and the orthotran granules were dissolved and only the cover film remained.

On the other hand, for the comparative example, 40 ° C., 80% R
In the H atmosphere, the polyvinyl alcohol film swelled due to moisture absorption and was deformed. Also in the drop test, the film strength was lowered, and as a result, the contents leaked from the torn portion.

From the above results, the water-soluble drug package of the present invention can protect the hygroscopic polyvinyl alcohol film and the drug from environmental humidity and maintain sufficient strength.

[Brief description of drawings]

FIG. 1 is a perspective view showing an embodiment in which the water-soluble drug package of the present invention is applied to a horticultural planter.

FIG. 2 is an exploded perspective view showing a package of a water-soluble drug of the present invention.

FIG. 3 is a vertical side view of the same.

FIG. 4 is a plan view of the same.

FIG. 5 is a vertical cross-sectional side view showing various examples in which the method of attaching the packaging body is different.

FIG. 6 is a vertical cross-sectional side view showing a use state when the same packaging body is simply laid on the ground.

FIG. 7 is a plan view showing an embodiment in which a broken line is provided between storage recesses.

[Explanation of symbols]

 1 Packaging film 2 Polyvinyl alcohol film 3 Moisture-proof film 4 Laminated film 5 Storage recess 6 Cover film 7 Adhesive layer 8 Release paper 9 Knob part 10 Adhesive 11 Magnet 12 Magnetic material 13 Thumbtack 14 Ground 15 Broken line P Gardening planter S Gardening fertilizer

Claims (4)

[Claims] 1. A polyvinyl alcohol film and a moisture-proof film are releasably adhered to each other to form a laminated film,
A storage recess is formed such that the polyvinyl alcohol film side of the laminated film is the inner surface, and a cover film is provided on the polyvinyl alcohol film side in a state where the water-soluble drug is stored in the storage recess. Pharmaceutical packaging. 2. The polyvinyl alcohol film has a saponification degree of 75 to 99 mol%, and the moisture-proof film has a moisture permeability of 100 g / m ² · 24 hours (40 ° C., 90% RH).
The water-soluble drug package according to claim 1, wherein: 3. The cover film is adhered to the polyvinyl alcohol film by heat fusion or a pressure-sensitive adhesive.
A package of the water-soluble drug described. 4. A knob is formed at an end of the laminated film by applying a release agent to a part of a laminated interface between the polyvinyl alcohol film and the moisture-proof film. The package of the water-soluble drug according to 2 or 3.