JPH0630762A - Bioreactor - Google Patents

Abstract

PURPOSE:To provide a bioreactor capable of increasing linear velocity of a liquid in a tank in which granular microorganism immobilized carrier is packed and capable of enhancing contact efficiency of a substrate with a microorganism. CONSTITUTION:The bioreactor fixes spiral blade 2 having 15-60 deg. blade angle thetato the horizontal face in the interior of cylindrical tank 1 and packs a granular microorganism immobilized carrier 3 in the space between these spiral blades 2. In this bioreactor, a substrate A is fed from a feed port 4 and made to react with the microorganism on the surface of the carrier 3 while passing through the carrier 3 and the product B is taken out from the outlet 5.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a bioreactor packed with a microorganism-immobilized carrier.

[0002]

2. Description of the Related Art A bioreactor having a vessel filled with a granular microorganism-immobilized carrier has been widely used. However, in such a bioreactor, the substrate supplied from the lower part thereof flows vertically upward between the microorganism-immobilized carriers in the tank and tries to reach the upper end through the shortest distance. The linear velocity cannot be increased. For this reason, there is a problem that the contact efficiency between the substrate and the microorganisms on the surface of the carrier becomes low.

[0003]

DISCLOSURE OF THE INVENTION The present invention solves the above-mentioned conventional problems and increases the linear velocity of a liquid in a tank filled with a granular microorganisms-immobilized carrier to improve the contact efficiency. It has been completed to provide a reactor.

[0004]

[MEANS FOR SOLVING THE PROBLEMS] The bioreactor of the present invention, which has been made to solve the above problems, fixes a spiral blade having a blade angle of 15 to 60 ° with respect to a horizontal plane inside a cylindrical tank. However, the space between the blades is filled with a granular microorganism-immobilized carrier.

[0005]

The present invention will be described below in more detail with reference to the illustrated embodiments. In FIG. 1, 1 is a cylindrical tank,
Reference numeral 2 is a spiral blade fixed inside the tank 1. As shown in the drawing, the spiral blade 2 is preferably provided at the center of the tank 1, and the end of the spiral blade 2 is preferably in contact with the inner wall of the tank 1. The space between the blades of the spiral blade 2 is filled with a granular microorganism-immobilized carrier 3. As the microorganism-immobilized carrier 3, a granular porous ceramic carrier or the like is used, and the particle size thereof is about 2 to 20 mm, more preferably 2 to 10 mm.
Keep it as a degree. If the particle size is too fine, gas escape will be poor, and if it is too coarse, the surface area will be small.

The above-mentioned spiral blade 2 has a blade angle θ with respect to the horizontal plane of 15 to 60 °. This is because if the blade angle θ is less than 15 °, the gas outflow in the tank is disturbed by the spiral blade 2 and if the blade angle θ exceeds 60 °, the gas outflow is improved, but the conventional spiral blade This is because the contact efficiency is not improved when the bioreactor without 2 is approached. A more preferable blade angle θ is 20 to 50 °. Also, regarding the shape of the tank 1, a value obtained by dividing the inner diameter by the height
The smaller the (D / H), the larger the linear flow velocity of the liquid flowing in the reactor and the higher the contact efficiency, but the pressure loss increases.
It is preferable to set D / H = 0.1 to 1.0, and D / H = 0.3 to
It is more preferable to set it to 0.6.

[0007]

In the bioreactor of the present invention thus constructed, the substrate is supplied from the supply port 4 at the lower end of the tank 1, and the granular microorganism-immobilized carrier 3 filled in the space between the spiral blades 2 is immobilized. The product is taken out from the outflow port 5 at the upper end of the tank 1 while passing through the inside and reacting with the microorganisms on the surface. As described above, the substrate tries to pass through the shortest distance, but in the present invention, since the spiral blade 2 is provided inside the tank 1, the substrate rises while spirally moving inside the tank 1. Become. Therefore, the linear velocity of the substrate can be increased, and the contact efficiency between the substrate and the microorganism can be increased.

Further, the gas generated by the reaction between the substrate and the microorganisms rises smoothly along the spiral blade 2 if the blade angle θ of the spiral blade 2 is set to 20 to 70 °, and the gas escape failure does not occur. . Therefore, the dead space due to the defective gas release is not formed, and the productivity of the bioreactor can be improved.

FIG. 2 is a graph showing the relationship between the blade angle θ and the production rate in the bioreactor of the present invention. Here, the vertical axis is the production rate in the conventional bioreactor without spiral blades, and the ratio is shown. As shown in this figure, the blade angle θ is 15-60 °
Then, the production rate can be improved to 1.4 to 2.0 times that of the conventional bioreactor.

[0010]

As described above, the bioreactor of the present invention has a cylindrical tank with a horizontal surface of 15-60.
By fixing spiral blades with a blade angle of ° and filling the space between the blades with a granular microbial immobilization carrier,
The linear velocity of the substrate passing through the microorganism-immobilized carrier can be increased without deteriorating the gas release, and the contact efficiency between the substrate and the microorganism can be increased to improve the production rate. Therefore, the present invention, as a bioreactor that eliminates the conventional problems, greatly contributes to industrial development.

[Brief description of drawings]

FIG. 1 is a cross-sectional view showing a bioreactor of the present invention.

FIG. 2 Blade angle θ in the bioreactor of the present invention
It is a graph which shows the relationship between and the ratio of a production speed.

[Explanation of symbols]

 1 tank 2 spiral blade 3 microorganism immobilization carrier

Claims (1)

[Claims] 1. A cylindrical tank having 15 to 15 horizontal planes.
A bioreactor characterized in that a spiral blade having a blade angle of 60 ° is fixed, and a space between the blades is filled with a granular microorganism-immobilized carrier.