JPH06296661A - Closure cap - Google Patents

Abstract

PURPOSE: To allow a simple and easy manufacture of a sealing cap to be put on the opening of a pharmaceutical container made of plastics, which can be inserted by a cannula, etc., without removing the part constituting the insertion spot. CONSTITUTION: The sealing cap to be put on the bottle head of a container to be inserted by a cannula or a syringe needle has a seal member 3 made of elastomer material and a sealing capsule 4 made of plastics. Both 3 and 4 are secured at the opening of a container by a securing ring 7, receiving the preload in the axial direction. As the seal member 3 and the sealing capsule 4 of which each opposed surfaces are formed as a ball joint shape, it is capable to make self-centering when the sealing cap is assembling, then the spot 2 for extracting fluid in the seal member 3 and the concave insertion spot 5 in the sealing capsule 4 are aligned. Another concave part 6 to be inserted by the syringe needle is also formed on the sealing capsule 4.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a closure cap for use in the opening of a container for medication, said closure cap comprising a sealing member of elastomeric material with a pierceable bleeding point. , A closure capsule made of plastic, with which the sealing member is crimped onto the opening of the container.

[0002]

2. Description of the Related Art Closure caps of this type are known from DE 2327554. The tearable cover portion of this known closure cap covers a sealing element made of an elastomeric material. To extract the medicine contained in this bottle,
The cover portion of the closure cap must first be removed so that the extraction portion of the seal member is exposed. Then
The extraction site is pierced by a cannula to extract the drug contained in the bottle. In this case, however, it should be noted that the production of the closure cap with the cleavable cover part limited by the sewing machine hole is not satisfactory in terms of manufacturing technology and economics. That is. Furthermore, the operation of the closure cap is problematic when the container is small in diameter. This is because removing the cover part with the tear piece is very cumbersome.

[0003]

SUMMARY OF THE INVENTION The object of the present invention is to improve the closure cap of the type mentioned at the beginning so that it is simpler to manufacture from the technical point of view, and more economically economical. To do so. Further, it would be desirable to improve the operation of the closure cap, especially when the container has a small diameter.

[0004]

In order to solve this problem, in the arrangement according to the invention, the closure capsule has at least one puncture point which at least partly coincides with the extraction point, which puncture point. However, it is pierceable without prior removal of the components of the closed capsule itself.

[0005]

In the arrangement according to the invention, the closure capsule has at least one puncture point which at least partly coincides with the extraction point, which puncture point preliminarily removes the constituent parts of the closure capsule itself. It can be penetrated without doing. The advantage here is that the closure cap consists of a very small number of individual parts, which can each be manufactured inexpensively by simple shaping.

The absence of a cleavable cover part in the area of the closed capsule also eliminates the need to provide a reference break site or machine holes in this area. Furthermore, the extraction of the drug from the container can be carried out quickly with a simple operation if necessary, and it is necessary to disassemble the closure cap into its constituent parts only at the time of waste disposal and subsequent reuse. The advantage is that To extract the liquid from the container, first the puncture point of the closed capsule and then the extraction point of the sealing member are pierced by a cannula or syringe. The elastomeric material of the seal member is radially preloaded and tightly surrounds the cannula. The sealing member is preferably composed of a thermoplastic elastomer material having a Shore A hardness of 45-60. This ensures that the sealing member provides the punctured cannula with the necessary holding action, while ensuring a significant sealing action on cannulas having different diameters. Moreover, these types of materials can be penetrated with the desired ease. Even if the container is placed so that its opening faces downward, the liquid component does not leak out along the cannula as a leak.

Advantageous configurations of the invention are described in the subclaims.

If the seal member is made of extremely soft rubber, it is not necessary to reduce the thickness of the extraction portion. In this way it is possible to form this sealing element from a flat disc. On the other hand, when a relatively hard type of rubber is used for manufacturing the seal member, it may be necessary to provide a cross-sectional area reduction portion in the extraction liquid region to facilitate penetration. Advantageously, such a reduced cross-sectional area is constructed in the form of a spherical notch. In this case, the edge area forms a sealing lip. These sealing lips adhere to the outer peripheral surface of the cannula after it has been pierced.

The wall thickness of the puncture site of the closed capsule may be thinner than the area of the closed capsule surrounding the puncture site.
The advantage here is that damage to the injection needle can be avoided when the injector is pierced through the closure cap into the container. According to a further advantageous development of the invention, the wall thickness in the puncture site region can be sheet-shaped and have a thickness of 0.1 to 0.8 mm.

The puncture site is restricted to a circular shape and may have a radially inwardly tapering wall thickness. With such a configuration, the puncture site of the closed capsule is never opened beyond the size that is absolutely necessary for puncturing the cannula. The puncture point of the closure capsule has a minimum wall thickness, approximately in the center above the extraction point of the sealing member. After the cannula has been punctured, the outer peripheral surface of the cannula is subjected to a radial preload and is tightly surrounded by a closed capsule, so that contamination in the extraction area is reliably avoided. Uncontrolled tearing of the puncture site is prevented by the gradual outward radial increase in the wall thickness of the closure capsule.

The puncture site is restricted to a circular shape and may have a radially inwardly tapered wall thickness. According to the first configuration, it is possible to provide the puncture site on the outer side, that is, on the side of the closed capsule that is separated from the container. The advantage in this case is that the puncture site can be easily recognized by the operator without the need for secondary aids such as markings. According to the second configuration, it is possible to provide the puncture site on the inner side, that is, on the closed capsule side facing the seal member. The advantage here is that the closed capsule has a flat surface on the side facing away from the container, which is free of recesses and protrusions. The smooth surface of the closed capsule makes it possible to clean this area particularly easily, for example after a closed container has been stocked for a relatively long period of time.

The closure capsule and the sealing member may have a predetermined mutual distance A at the puncture site. Due to this mutual spacing A, the closure capsule in the region of its puncture point is first elastically tension-loaded during puncture of the cannula and thus pierced with relatively little force.

Only when the surface of the closed capsule has already been penetrated, the extraction portion of the sealing member is penetrated.

The closed capsule may be made of a plastic containing a germicidal substance. This simplifies the sealed and aseptic seal of the drug contained in the container.

[0015]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT An embodiment of a closure cap according to the present invention will be described below in detail with reference to the drawings.

FIG. 1 shows an embodiment of a closure cap according to the invention for closing a drug-filled container 1. This closure cap consists of three separate parts. These separate parts are a sealing member 3 made of an elastomeric material and a closure capsule 4 made of plastic.
And a fixing ring 7 made of light metal. The sealing member 3 and the closed capsule 4 are preloaded in the axial direction by the fixing ring 7 and the container 1
It is fixed to the opening. The fixing ring 7 is grasped so as to surround the closed capsule 4 and the bottle neck portion of the container 1 in the axial direction. The fixing ring 7 is curved at the area of the projection of the bottle neck. Since the sealing member 3 and the closing capsule 4 are formed in the shape of a ball joint in the areas of the surfaces facing each other, when the closing cap is assembled, the self-centering of the components is performed, whereby the extraction of the sealing member 3 is performed. The point 2 and the puncture point 5 of the closed capsule 4 coincide.

In this embodiment, the puncture point 5 of the closed capsule 4 is formed by a recess on the side remote from the container 1. The puncture site 5 is restricted to a circular shape, and has a thinner wall thickness in the area of the circular restriction portion than in the area that is located continuously in the radial direction. The puncture site 5 is provided with another trough-shaped recess 6 so as to be adjacent to the puncture site 5 at a predetermined interval in the radial direction. This recess can be penetrated by an additional injection needle. With such a configuration, the drug inside the container 1 can be extracted by two cannulas, or another liquid component can be additionally supplied to the drug inside the container 1.

The closing capsule 4 and the sealing member 3 have a mutual distance A at the puncture site. This mutual distance A
Is preferably 1 to 5 mm. The magnitude of this mutual spacing A is mainly related to the elastic flexibility of the closed encapsulant material. It is advantageous to dimension this mutual distance A such that the cannula contacts the sealing member 3 in the region of the extraction point 2 only after the puncture point 5 of the closure capsule 4 has already been penetrated by the cannula.

FIG. 2 shows the area of the bottle neck of the container 1. The closure cap is penetrated by the cannula of the infusion container 8 and the injection needle of the injector 9. The injector 9 supplies additional liquid to the drug inside the container 1. The drug inside the container 1 is then extracted by a cannula that penetrates through the middle of the closure cap. The sealing on the outer peripheral surface of the injection needle of the injector 9 and on the outer peripheral surface of the cannula of the infusion container 8 is carried out by the elastomeric material of the sealing member 3 and in the area of the puncture point 5 and the recess 6 the seat of the closing capsule 4. It is also performed by the material of the shape. Even when the container is arranged in a suspended manner as shown in the drawing, there is no risk of liquid loss from the container 1.

In order to make the fixing ring 7 severable, in this embodiment, a fixing ring 7 made of light metal is provided with a cleaving ring 10 capable of cleaving. This allows these components to be separated from each other, for example after the container 1 has been emptied, in order to provide the used components for recycling.

Furthermore, after the fixing ring 7, the closing cap 4 and the sealing member 3 are removed, the drug in the container can be emptied.

When the dehiscence ring 10 is manipulated, for example, a segment is removed from the fixing ring 7 to form a notch, which enables the fixing ring to be removed from the neck of the bottle without any problems. This closure cap 4
The seal member 3 and the container 1 can be separated from each other without any problem.

[Brief description of drawings]

FIG. 1 shows a bottle neck of a container filled with drug and closed by a closure cap.

FIG. 2 is a view of the container portion shown in FIG. 1 in which the container is placed in a suspended state and the closed portion is penetrated by a cannula.

[Explanation of symbols]

1 container, 2 extraction points, 3 sealing member, 4
Closing capsule, 5 puncture points, 6 recesses, 7 fixing ring, 8 infusion container, 9 injector, 10 cleaving ring, A mutual spacing

Claims (5)

[Claims] 1. A closure cap for use in the opening of a container for medication, said closure cap comprising a sealing member (3) made of an elastomeric material with a pierceable bleed point and made of plastic. A closed capsule (4), wherein the sealing capsule (4) is crimped onto the opening of the container with the closed capsule (4). Characterized in that it has at least one puncture point which corresponds to the extraction point (2), which is pierceable without prior removal of the components of the closed capsule (4) itself. And a closing cap. 2. Closure cap according to claim 1, wherein the closure capsule (4) has a thinner wall thickness at the puncture site (5) than at the closure capsule area surrounding the puncture site (5). 3. Closure cap according to claim 2, wherein the puncture point (5) is restricted to a circular shape and has a wall thickness which tapers radially inward. 4. A closed capsule (4) and a sealing member (3).
And have a mutual spacing A at the puncture point (5),
Closure cap according to any one of claims 1 to 3. 5. The closed capsule (4) is manufactured from a plastic containing a germicidal substance.
The closure cap according to claim 1.