JPH06225943A - Reservoir - Google Patents

Abstract

PURPOSE:To provide a reservoir which is adapted to avoid the tearing of a silicone plug especially as caused by puncture with an injection needle concerning the reservoir which is left in vivo to dose a medicine, through a catheter by percutaneous puncture. CONSTITUTION:This reservoir comprises a lower frame 1 having a recess part at the center thereof while having a connector 8 to be connected to a catheter communicating with the outside through the recess part, a silicone plug 5 covering the top surface of the recess part and an upper frame 2 to fix the silicone plug. In the reservoir, a pressure sensitive adhesive layers 6 and 7 are interposed between the recess part and the silicone plug.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a reservoir which is placed in the body and administers a drug via a catheter by percutaneous puncture.

[0002]

2. Description of the Related Art In recent years, a reservoir has been used as a device for indwelling in the body and percutaneously puncturing to administer a drug into a vein or an artery via a catheter.

A conventional reservoir is shown in FIG.
Shown in. In FIG. 2, the reservoir A is connected to a catheter C placed in a body cavity or a blood vessel and is embedded under the skin B, and the drug is a silicone on the ceiling of the reservoir.
It is injected by percutaneously puncturing the stopper 5 with a syringe D. Then, the drug is made to reach the target site via the catheter C connected to the reservoir A.

However, in the reservoir having such a structure, each time a drug is injected, the silicone on the ceiling is
A needle is punctured in the stopper, and as a result, the silicone portion gradually becomes unbearable for puncturing with the needle due to tearing by the needle tip.

Various measures have been taken in order to improve this point. For example, a titanium ring is fitted on the outer periphery of a silicone plug to caulk the silicone portion from the surroundings to close the puncture hole, or The shape of the needle tip for injecting the drug is, for example, Huber point needl so as to eliminate eating by the needle tip. However, such a method is not yet sufficient.

[0006]

The present inventor has completed the present invention as a result of various studies to improve the above points and to withstand the puncture of an injection needle. As a result, the present invention has been completed. It is an object of the present invention to provide a reservoir designed to avoid the rupture of the silicone stopper due to the needle puncture.

[0007]

DISCLOSURE OF THE INVENTION The gist of the present invention is to provide a lower frame which has a recess in the center and a connector which communicates with the outside from the recess and can be connected to a caterer.
And a silicone stopper covering the upper surface of the recess and the silicone stopper.
Reservoir consisting of an upper frame for fixing the stopper from above
A reservoir is characterized in that an adhesive layer is interposed between the recess and the silicone stopper.

That is, in the present invention, by interposing an adhesive layer between the silicone stopper on the recess and the recess, the needle punctures the silicone stopper and injects the drug into the recess,
When the needle was pulled out, the hole of the needle was blocked by the contraction of the adhesive layer, so that the damage caused by the injection needle was covered, and when the needle was pulled out, the needle hole could be blocked by the adhesive.

A reservoir according to the present invention will be described with reference to the drawings. FIG. 1 is a sectional view of the reservoir. In FIG. 1, a recess A is provided at the center of the lower frame 1,
A titanium plate 4 is fitted into the bottom surface of the recess.
A connector 8 is provided on the side wall 3 of the recess A so as to be joined to a catheter. The top surface of the recess A is covered with a silicone plug 5 with adhesive layers 6 and 7 interposed therebetween. The silicone plug 5 is inserted into the upper frame 2 to integrally form a lid, which is fitted into the upper surface of the recess A of the lower frame 1 to close the recess A, and to surround the metal. The ring 9 is caulked from the outside to fix the lid. All of these are
Covered with elastomer-10. The reservoir having such a structure is embedded under the skin and joined to the end of the catheter left in the body by the connector-8. When administering the drug solution into the body, the skin is punctured with an injection needle, the silicone stopper is penetrated, and the drug is injected into a recessed portion provided in the center of the lower frame.

The upper frame 2 and the lower frame 1 used in the present invention are preferably made of a material having a slight elasticity, such as trimethylpentene or polyethersulfone, and the silicone used for the silicone stopper. A silicone elastomer is used as the mold, and these are molded by means such as injection molding. The pressure-sensitive adhesive layer interposed between the upper surface of the recess and the silicone stopper may be a single layer or a multilayer of two or more layers, and the material used for this is preferably a silicone pressure-sensitive adhesive or the like.

Next, a method for manufacturing the reservoir of the present invention will be described. Silicon Elastomer (Dow Corning
Q7-4750 (manufactured by Dow Corning) is used to mold the silicone stopper 5 shown in FIG. 1 by injection. The lower surface of the silicone stopper is washed with an acetone solution to degrease it. Then, a primer is applied to this surface. Silicone primer XY (manufactured by Toray Industries, Inc.) is used as a primer. A silicone adhesive (Dow Corning 355 Dow Corning as a medical adhesive on the surface coated with the primer.
Ning medical adhesive (silicon content 18.5
%)) Is applied to the surface to a thickness of 0.1 to 0.3%, and heat treatment is performed at 180 ° C. for 1 hour to crosslink.

Next, 1 part of silicone oil (Q7-2146 manufactured by Dow Corning) and silicone oil (Q7-2146 manufactured by Dow Corning)
-2150) 0.3 to 1 mm on a mixture of 3 parts on the upper surface of the silicon stopper and the surface coated with the above-mentioned silicone adhesive.
And apply heat treatment at 180 ° C. for 1 hour. The silicone plug 5 which has been subjected to the above treatment is inserted into the upper frame 2 and then inserted into the lower frame 1. Further, a titanium ring 10 is caulked from the outside to fix the silicone plug. By doing so, thermal expansion and plastic deformation of the plastic portion of the frame portion are suppressed, and the silicone elastomer of the silicone stopper is pushed from the outside, and the needle of the silicone elastomer is always held. Restoring when the needle is removed by tightening pressure toward the center of the entry part. The production example described above is an example of the present invention, and the adhesive layer used in the present invention is not limited to this.

[0013]

As described above, in the present invention, when the injection needle is inserted through the silicone stopper and further pulled out, the lower layer in the silicone gel state is formed as compared with the conventional silicone rubber layer alone. There is an effect that it shrinks well and covers the damage of the silicone rubber layer on the upper side, and self-repairs by the internal pressure.

[Brief description of drawings]

FIG. 1 is a sectional view of a reservoir according to the present invention.

FIG. 2 is an explanatory view of a conventional reservoir embedded in the body.

[Explanation of symbols]

1 Lower Frame 6 Adhesive Layer 2 Upper Frame 7 Adhesive Layer 3 Sidewall of Reservoir 8 Connector 4 Titanium Plate 9 Metal Ring 5 Silicone Stopper 10 Silicone Elastomer

Claims (1)

[Claims] 1. A lower frame having a recess at the center and a connector communicating with the outside from the recess so as to be connectable to a catheter, and a silicone covering the upper surface of the recess. A reservoir comprising a stopper and an upper frame for fixing the silicone stopper, wherein a pressure-sensitive adhesive layer is interposed between the recess and the silicone stopper.