JPH0617288B2 - Agro-horticultural wettable powder composition - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to an agricultural and horticultural wettable powder containing aluminum tris (ethyl phosphonate) (hereinafter abbreviated as fosetyl) as an active ingredient and having improved physical properties. It relates to a composition.

[Prior Art] Fosetyl is a compound showing excellent activity against fungi and having high safety, and is used as a useful agricultural and horticultural fungicide.

Agro-horticultural wettable powder composition containing fosetyl as an active ingredient has useful properties from the viewpoint of controlling important diseases, while other water-dispersible agricultural and horticultural powders at the time of adjusting the dilution with water during spraying. However, when used in combination with other agents such as emulsions, fixing agents or fertilizers (including fertilizers, the same applies below), it has the drawback that aggregation tends to occur, which is often seen as an obstacle to practical use. .

A surfactant is generally used for the purpose of preventing aggregation in such a mixed use situation. For example, alkylbenzene sulfonate, alkylnaphthalene sulfonate, dialkyl sulfosuccinate, polyoxyethylene alkylaryl sulfate. Anionic surfactants such as ester salts, and one or more selected from nonionic surfactants such as polyoxyethylene alkyl ether, polyoxyethylene alkylaryl ether, and polyoxyethylene fatty acid ester are mixed in the formulation. Therefore, it is often the case that measures are taken to prevent aggregation when mixed with other drugs.

Further, as an additive other than the surfactant, sodium tripolyphosphate may be used (JP-A-58-67603).

[Problems to be solved by the invention]

However, with regard to the agricultural and horticultural wettable powder composition containing fosetyl as an active ingredient, even when the surfactant or sodium tripolyphosphate or the like according to the conventional technique is used, the occurrence of aggregation when mixed with other drugs is almost prevented. Therefore, a sufficiently satisfactory preparation was not obtained in use.

As a method for controlling pests in recent years, other fungicides, insecticides, spreading agents, fixing agents or fertilizers or other agents are simultaneously diluted with water for the purpose of improving their efficiency, and then a sprayer is used. Is often sprayed.

In such a case, the occurrence of agglomeration in the mixed dilution adjusting solution is preferable because it is against the original purpose such as the chemical damage and the reduction of the control effect, because the homogeneity of the diluting solution is impaired as the agglomerates settle or float. The result is no, and the agglomerates can clog the sprayer nozzles making spraying impossible.

In a wettable powder composition for agricultural and horticultural use containing fosetyl as an active ingredient, compatibility with other drugs is remarkably poor and, for example, zinc ion coordination manganese ethylene bisdithiocarbamate, 8-hydroxyquinoline copper, dimethyldicarbetoxy. In a situation where it is mixed with many useful agricultural and horticultural agents and fertilizers, including agents containing ethyldithiophosphate or cupric mercuride as an active ingredient,
The present situation is that it has been difficult to see the occurrence of aggregation, which is a problem in practice. Even when there is no substantial hindrance during spraying, the product value is often questioned by the user due to the occurrence of coagulation due to mixing.

In such a situation, in the agricultural and horticultural wettable powder composition containing fosetyl as an active ingredient, the occurrence of aggregation is prevented by the improvement of miscibility with other agents, and good physical properties desired in use are obtained. The development of equipped preparations has been desired.

[Means for solving problems]

The present inventors aimed to ameliorate the above-mentioned conventional problems, and as a result of conducting a search on a large number of compounds, as a result of other pharmaceutical agents for agricultural and horticultural wettable powders containing fosetyl as an active ingredient. It was found that the addition of a compound selected from organic acids or salts thereof can improve the compatibility of the compound with a particularly high effect and is extremely effective in solving the above-mentioned problems. The present invention has been completed.

The present invention provides a powdered preparation containing aluminum tris (ethyl phosphonate) as an active ingredient, and one or more compounds selected from organic acids and salts thereof as a miscibility improver with other drugs. It is a wettable powder composition for agricultural and horticultural use with good physical properties, characterized in that it is composed of a powdery mixture.

The active ingredient in the present invention is fosetyl, but other active ingredients may be added.

The organic acids and salts thereof used as the compatibility improver in the present invention are compounds having a carboxyl group in the molecule and salts thereof such as alkali metal salts, alkaline earth metal salts and ammonium salts, and specifically, For example, malic acid, sodium malate, ammonium malate, citric acid, sodium citrate, potassium citrate, ammonium citrate, tartaric acid, sodium tartrate, potassium tartrate, ammonium tartrate, fumaric acid, sodium fumarate, ammonium fumarate, shu Sodium acid,
Sodium formate, maleic acid, sodium maleate,
Examples thereof include calcium maleate, malonic acid, sodium malonate, potassium malonate, succinic acid, sodium succinate, ammonium succinate, sodium acetate, potassium acetate and ammonium acetate.

When compounding these compounds into a wettable powder composition for agricultural and horticultural use containing fosetyl as an active ingredient, the range of 0.01 to 0.5 parts by weight is usually preferable to 1 part by weight of fosetyl, preferably 0.02 to 0.2 parts by weight. Blend in the range of.

In order to improve the stability of an aqueous solution containing fosetyl as an active ingredient, a method has already been proposed in which a weak acid such as calcium acetate and a salt of a strong base are blended as a stabilizer (JP-A-59).
-184112), unlike the liquid formulation, the wettable powder of the present invention is composed of a powdery mixture and is diluted with water at the time of use and applied in a short time. In addition, the above-mentioned conventional example does not disclose the aggregation when the wettable powder is mixed with another drug, and the application field and effect are different from the present invention.

The agricultural and horticultural wettable powder composition according to the present invention can be produced by mixing and crushing fosetyl and the above-mentioned miscibility improver by a usual method. In this case, upon mixing, for example, a surfactant, a bulking agent and the like are added if necessary, and then uniformly mixed and pulverized by a usual method for producing a wettable powder composition for agricultural and horticultural use.

Examples of the surfactant include nonionic ones such as polyoxyethylene alkyl ether, polyoxyethylene alkylaryl ether, polyoxyethylene fatty acid ester and polyoxyethylene sorbitan fatty acid ester, and fatty acid salt (sodium phenate), alkyl sulfate. Ester salt, dialkyl sulfosuccinate, alkyl phosphate ester salt, naphthalene sulfonic acid formalin condensate,
Examples thereof include anionic ones such as polyoxyethylene alkyl sulfate ester salt and lignin sulfonate.

As the extender, clay, diatomaceous earth, talc, bentonite, calcium carbonate, white carbon, and other fine mineral powder, ammonium sulfate, salt such as mirabilite, and organic substances such as sugar, cellulose powder, and urea can be used.

The agricultural and horticultural wettable powder composition of the present invention, as long as it does not impair the object of the present invention, if necessary, other fungicides, insecticides,
Other agents such as a spreading agent, a sticking agent, a plant growth regulator, a synergist, an attractant, a repellent, and a fertilizer can also be mixed and mixed, but a wettable powder, an emulsion or the like of these agents can also be mixed. It can also be dissolved and mixed at the same time as the preparation.

Specific examples of other agents that can be mixed or mixed by simultaneous dissolution include, for example, organophosphorus fungicides, organochlorine fungicides, benzimidazole fungicides, copper fungicides, organosulfur fungicides, and dithio. Carbamate fungicides, antibiotics,
Natural insecticide, pyrethroid insecticide, organophosphorus insecticide,
Organic chlorine insecticides, carbamate insecticides, urea complex liquid fertilizers and the like can be mentioned.

When the wettable powder composition of the present invention is mixed with another drug, the wettable powder composition of the present invention, another drug, and the like are simultaneously diluted and adjusted with water and then sprayed by a sprayer or the like.

[Work]

The above-mentioned wettable powder composition for agricultural and horticultural use according to the present invention has been problematic in conventional formulation techniques when other drugs are blended or dissolved and mixed at the same time with other drugs.
In addition to preventing agglomeration when mixed with other chemicals, good physical properties desired in use such as hydration property, suspension property, fineness of powder, and dispersibility in water can be obtained.

〔Example〕

Next, the present invention will be specifically described with reference to examples, but the present invention is not limited thereto. In addition, the part in an Example means a weight part.

Example-1 80 parts of fosetyl, 5 parts of sodium tartrate, 2 parts of sodium dialkylsulfosuccinate, 2 parts of polyoxyethylene alkylaryl ether, 3 parts of sodium lignin sulfonate, and 8 parts of diatomaceous earth were mixed and then pulverized to obtain a wettable powder. And

Example-2 80 parts of fosetyl, 5 parts of citric acid, 2 parts of sodium alkylbenzenesulfonate, 3 parts of ammonium polyoxyethylene alkylaryl ether sulfate, and 10 parts of diatomaceous earth are mixed and ground to obtain a wettable powder.

Example 3 40 parts of fosetyl, 40 parts of N-trichloromethylthiotetrahydrophthalimide, 4 parts of sodium malate, 3 parts of sodium alkyl ester sulfate, 3 parts of polyoxyethylene alkylaryl ether, and 10 parts of clay were mixed and then ground. Use as a Japanese medicine.

Example 4 40 parts of fosetyl, 40 parts of N-trichloromethylthiotetrahydrophthalimide, 5 parts of succinic acid, 3 parts of sodium alkylbenzene sulfonate, 3 parts of polyoxyethylene alkylaryl ether, and 9 parts of diatomaceous earth were mixed and then ground. Use as a Japanese medicine.

Example-5 35 parts of fosetyl, 35 parts of manganese ethylene bisdithiocarbamate with zinc ion coordination, 4 parts of sodium tartrate
Parts, 3 parts of sodium alkylbenzene sulfonate, 3 parts of sodium alkylnaphthalene sulfonate, and 20 parts of diatomaceous earth are mixed and ground to obtain a wettable powder.

Example-6 Fosetyl 35 parts, zinc ion coordination manganese ethylene bisdithiocarbamate 35 parts, sodium citrate 4
Parts, sodium alkylnaphthalene sulfonate 2 parts, polyoxyethylene alkylaryl ether 2 parts, sodium dialkyl sulfosuccinate 2 parts, white carbon 2 parts, and clay 18 parts are mixed and ground to obtain a wettable powder.

For comparison, examples of blending by a technique which does not belong to the scope of the present invention or a known technique are listed below as reference examples.

Reference Example-1 80 parts of fosetyl, 2 parts of sodium dialkylsulfosuccinate, 2 polyoxyethylene alkylaryl ethers
Parts, 3 parts of sodium ligninsulfonate, 5 parts of sodium tripolyphosphate, and 8 parts of diatomaceous earth are mixed and ground to obtain a wettable powder.

Reference Example-2 80 parts of fosetyl, 2 parts of sodium alkylbenzene sulfonate, 3 parts of polyoxyethylene alkylaryl ether ammonium sulfate, and 15 parts of diatomaceous earth are mixed and ground to obtain a wettable powder.

Reference Example-3 40 parts of fosetyl, 40 parts of N-trichloromethylthiotetrahydrophthalimide, 3 parts of sodium alkyl ester sulfate, 3 parts of polyoxyethylene alkylaryl ether, and 14 parts of clay are mixed and then pulverized to obtain a wettable powder.

Reference Example-4 40 parts of fosetyl, 40 parts of N-trichloromethylthiotetrahydrophthalimide, 3 parts of sodium alkylbenzene sulfonate, 3 parts of polyoxyethylene alkylaryl ether, and 14 parts of diatomaceous earth are mixed and ground to obtain a wettable powder.

Reference Example-5: 35 parts of fosetyl, 35 parts of zinc ion-coordinated manganese ethylene bisdithiocarbamate, 3 parts of sodium alkylbenzene sulfonate, 3 parts of alkylnaphthalene sulfonic acid, and 24 parts of diatomaceous earth were mixed and ground to obtain a wettable powder. To do.

Reference Example-6 35 parts of fosetyl, 35 parts of zinc ion coordinated manganese ethylenebisdithiocarbamate, 2 parts of sodium alkylnaphthalenesulfonate, 2 parts of polyoxyethylene alkylaryl ether, 2 parts of sodium dialkylsulfosuccinate, 4 parts of sodium tripolyphosphate , 2 parts of white carbon, and 18 parts of clay are mixed and ground to obtain a wettable powder.

Test Example Next, the effect of the present invention will be specifically described with reference to a test example. The test method in each test example was as follows.

Mixability test method In a beaker with a capacity of 1, add 1 degree of hard water at 20 ° C,
The mixing partner drug shown below is diluted and stirred in advance at a predetermined dilution ratio, and the samples shown in Examples and Reference Examples are added at a dilution ratio, and they are sufficiently mixed and stirred. After standing for 1 hour, the degree of aggregation that has occurred is observed and judged for practicality.

Mixture partner drug Mixture-1 Fungicide-A (8-Hydroxyquinoline copper wettable powder) Mixture-2 Fungicide-B (Kasugamycin-hydrochloride / basic copper chloride wettable powder) Mixture-3 Pesticide-A (( RS) -α-Cyano-3-phenoxybenzyl = (RS) -2- (4-chlorophenyl) -3-
Methylbutanoate / Dimethyldicarbetoxyethyldithiophosphate wettable powder) Mixed -4 Insecticide-B (S-methyl-N-[(methylcarbamoyl) oxy] thioacetimidate wettable powder) Fertilizer-A (Urea compound liquid fertilizer) Mixed-5 insecticide-C (O, O-dimethyl-S {5-methoxy-1,3,4
-Thiadiazol-2 (3H) onyl- (3) -methyl} dithiophosphate emulsion) Fungicide-C (1-4-chlorophenoxy) -3,3-dimethyl-1- (1,2,4-triazole -1-yl) -2-
Butanone wettable powder) Table 1 shows the results of the compatibility test with other drugs and the like of the formulations shown in Examples and Reference Examples.

From the above results, it can be seen that the wettable powder for agricultural and horticultural use according to the present invention exhibits better compatibility with other drugs as compared with the preparations according to the known techniques mentioned as reference examples.

〔The invention's effect〕

The agricultural and horticultural wettable powder composition of the present invention contains an organic acid or a salt thereof in a powdered preparation containing fosetyl as an active ingredient.
In addition to exhibiting excellent compatibility, it prevents coagulation when mixed with other drugs, and has excellent physicochemical properties such as hydration, suspension, fineness and dispersibility in water, which are desirable for use. Moreover, it is not only toxic to human resources, but also toxic to agricultural and horticultural plants.

Claims (3)

[Claims] 1. A granular preparation containing aluminum tris (ethyl phosphonate) as an active ingredient, and one or more compounds selected from organic acids and salts thereof as a miscibility improver with other drugs. A wettable powder composition for agricultural and horticultural use having good physical properties, characterized in that the wettable powder composition comprises a mixed powdery mixture. 2. The compatibility improver is malic acid, sodium malate, ammonium malate, citric acid, sodium citrate, potassium citrate, ammonium citrate, tartaric acid, sodium tartrate, potassium tartrate, ammonium tartrate, fumaric acid, Sodium fumarate, ammonium fumarate, sodium oxalate, sodium formate, maleic acid, sodium maleate, calcium maleate, malonic acid, sodium malonate, potassium malonate, succinic acid, sodium succinate, ammonium succinate, sodium acetate The wettable powder composition for agricultural and horticultural use according to claim 1, wherein the wettable powder composition is potassium acetate, potassium acetate, or ammonium acetate. 3. The other drug is a bactericide, insecticide, spreading agent, sticking agent, plant growth regulator, synergist attractant, repellent, or fertilizer. A wettable powder composition for agricultural and horticultural use according to the item.