JPH06102282A - Autoanalyzer for blood equipped with cleaning mechanism - Google Patents

Abstract

PURPOSE:To allow application even to analysis requiring long reaction time by providing a single up/down mechanism with a plurality of cleaning nozzles and lowering each nozzle independently. CONSTITUTION:A reaction table 1 stops temporarily after rotation of semicircle plus one cup (corresponding to 61 pieces of reaction caps) and then rotates by semicircle plus one cup again. This operation is repeated. Single rotation requires about 20min. In such operation of the reaction table 1, each cup repeates same operation with 20min cycle. A single arm 8 having up/down mechanism is provided with a plurality of cleaning nozzles 7 perfoming discharge of sample-injection of cleaning water-discharge of cleaning water, where each nozzle is locked by a solenoid 9 and moves up and down independently. Since the operation of the nozzle 7 lowering into the reaction cup can be eliminated at least once during 20min (one cycle), it is possible to make progress the reaction during first 20min and to make measurement during next 20min thus allowing measurement even of a long time reaction.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention, in an analyzer for quantitatively measuring a specific component in blood, automatically dispenses serum and reagents, holds a reaction solution, measures and cleans a reaction cup. Blood analyzer.

[0002]

2. Description of the Related Art A conventional automatic blood analyzer cleaning method is as follows.
It has a plurality of cleaning nozzles, the role of each nozzle is fixed, and the plurality of cleaning nozzles are installed in the same arm on the vertical mechanism. The raising and lowering mechanism is installed close to the reaction cup table, and a plurality of nozzles are moved up and down at the same time under the time control of a computer to wash each nozzle.
Water absorption-rewashing was performed on the reaction cup stopped just below the nozzle.

[0003]

Therefore, the reaction time after injection of the serum and the reagent into the reaction cup is largely influenced by the time sequence of the reaction cup table, and even if the reaction time is changed, The time sequence of the table was difficult, and it was difficult to provide an automatic blood analyzer that can support various types of reactions. Therefore, in the conventional apparatus, the reaction time was fixed, and the time sequence of the table was devised so that the reaction time could be selected from 2 to 3 stages.

However, in recent years, there has been an increasing demand for an analyzer which can cope with immunoassays having a long reaction time in addition to improving the processing capacity and reducing the amount of a sample.

An object of the present invention is to provide a blood analyzer for use in the analysis which has a relatively long reaction time such as an immunoassay in addition to the improvement of the processing capacity of the device and the miniaturization of a sample which are required by the customer. Especially.

[0006]

Means for Solving the Problems The reaction time of the serum and the reagent injected into the reaction cup can be varied to some extent by devising the time sequence of the rotation of the reaction cup table. However, the processing capacity of an automatic analyzer is two major factors along with the ability to support an analytical method, and the rotation of the table cannot be unnecessarily slowed down. Thus, there is a limit to the rotation of the reaction cup table, and an obstacle to changing the reaction time without depending on the rotation of the table exists in the operation of the cleaning mechanism.

[0007] Now, when the nozzles for sample discharge-washing liquid injection-washing liquid discharge are moving up and down at the same time, the nozzles are lowered independently, and the washing operation is repeated as necessary to treat the reaction cup. The reaction time can be changed without reducing the ability.

[0008]

In the conventional apparatus as well, the reaction time is varied by devising the rotation of the reaction cup and providing a plurality of cleaning mechanisms. However, for analysis with a long reaction time (for example, 20 minutes or more), the rotation of the reaction cup table cannot be slowed down in view of the processing capacity, so that 1 cycle is always required during one cycle.
The washing nozzle descends into all the reaction cups, and even the sample in the middle of reaction is useless. Already,
If it can be excluded that the temperature always drops once in one cycle, the reaction solution can be stored until the next cycle, and analysis with a long reaction time can be simultaneously performed without lowering the processing capacity of the apparatus. For this purpose, if each washing nozzle is provided on the arm of one vertical mechanism and only the lowering operation of that nozzle can be performed independently, the lowering of the washing nozzle to the unnecessary reaction cup is prevented. it can. This enables measurement on the same reaction cup table regardless of the length of the reaction time.

[0009]

EXAMPLE An example of the present invention will be described below with reference to FIG.

FIG. 1 is a block diagram of the vicinity of a reaction table 1 of a conventional automatic blood analyzer having a cleaning mechanism in which each cleaning nozzle 7 moves up and down at the same time. First, the reaction table 1
It rotates for half a round + 1 cup (61 reaction cups), pauses, and then rotates again for a half round + 1 cup. After that, this operation is repeated. It takes about 20 seconds for one rotation. In the operation of such a reaction table, each cup repeats the same operation in a cycle of 20 minutes, and if the reaction time is longer than 20 minutes, the reaction time is 20 minutes in the reaction cup even though the measurement time is not yet reached. Since each cleaning nozzle descends once every time, the reaction is hindered and measurement becomes impossible.

FIG. 2 shows an embodiment according to the present invention.

As in the conventional cleaning nozzle, a plurality of cleaning nozzles 7 are provided on one arm 8 which moves up and down, and each nozzle has a role of sample discharge-cleaning water injection-cleaning water discharge. Is. Each nozzle is normally a solenoid 9
Each of them is moved up and down according to the up and down movement of the arm.

By this, the operation in which the cleaning nozzle descends into the reaction cup can be excluded once in every 20 minutes (1 cycle). Therefore, the reaction is carried out in the first 20 minutes and then in the next 20 minutes. It is possible to measure, and it is possible to measure a long-time reaction, which was difficult with conventional devices, with an automatic analyzer. From this, it can be easily imagined that the measurement time of the third cycle and the measurement of the fourth cycle and the reaction time can be infinitely lengthened.

[0014]

As described above, according to the present invention, a plurality of cleaning nozzles are provided on one vertical mechanism arm as an automatic cleaning mechanism, and each nozzle can be independently lowered into the reaction cup. It is possible to provide an automatic blood analyzer capable of performing analysis with a long reaction time without deteriorating the ability.

[Brief description of drawings]

FIG. 1 is a configuration diagram around a conventional reaction table.

FIG. 2 is a diagram showing an embodiment according to the present invention.

[Explanation of symbols]

1 ... Reaction table, 2 ... Reaction cup, 3 ... Washing mechanism, 4
... Dispensing mechanism, 5 ... Reagent disk, 6 ... Sampling, 7
... wash nozzle, 8 ... wash arm, 9 ... solenoid.

Claims (1)

[Claims] 1. An automatic blood analyzer for quantitatively analyzing a certain component in blood, wherein an upper and lower mechanism arm has a plurality of washing nozzles as an automatic washing mechanism for a reaction vessel, and the plurality of nozzles are provided. An automatic blood analyzer with a cleaning mechanism that can be lowered independently.