JPH06102266A - Gas chromatography - Google Patents

Abstract

PURPOSE:To prolong the lifetime of analytical column by automatically sustaining the temperature of a column oven at a level lower than the initial temperature for a predetermined time upon finish of entire analysis. CONSTITUTION:The gas chromatography comprises a column oven 1, an analytical column 2, a sample injecting section 3, a flow rate regulating section 4, a detecting section 5, and a main control section 6 as well as an end of entire analysis decision mechanism 7 and an analytical parameter memory 8. Analytical parameters are set upon start of analysis whereas a sustaining temperature lower than the initial temperature and a sustaining time thereof are set upon finish of entire analysis. The analytical parameters are stored in the analytical parameter memory 8. Every time when an analysis is finished, the end of entire analysis decision mechanism 7 functions in reference to the data stored in the memory 8. If a decision is made that the analysis has not ended entirely, the analysis is repeated otherwise the temperature of the column oven 1 is sustained automatically at a level lower than the initial temperature for a predetermined time.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a gas chromatograph for extending the life of an analytical column.

[0002]

2. Description of the Related Art In the prior art, the temperature is returned to the initial temperature after the analysis is completed, and in order to prolong the life of the analytical column, only the temperature of the column oven is automatically adjusted to a constant temperature lower than the initial temperature within a fixed time. The conventional technology does not have the function of holding at.

[0003]

In order to perform analysis with a gas chromatograph with high sensitivity, accuracy, and efficiency, it is essential to stabilize the device, and therefore, even when the analysis is not in progress, Means such as keeping the temperature of the temperature control unit (column oven, sample injection unit, detection unit) in the analysis state (high temperature state) are taken. However, keeping the analytical column always in a high temperature column oven leads to a shortened life of the analytical column. Therefore, the above method is a method for stabilizing the apparatus in a short period of time, but in the long term, it deteriorates the column earlier and is not necessarily a method for stabilizing the apparatus.

Therefore, in order to achieve both high sensitivity, high accuracy, high efficiency of analysis and a long life of the analytical column, a person operates at the end of the entire analysis to set the temperature of the column oven to a low temperature. I was doing it.

According to the present invention, only by inputting the analysis parameter before starting the analysis, the temperature of the column oven is automatically lower than the initial temperature at the end of the whole analysis, and the column efficiency is not lowered so much. The present invention also provides a gas chromatograph that can be held for a certain period of time and then automatically set to an initial temperature. Therefore, an object of the present invention is to extend the life of the analytical column.

[0006]

[Means for Solving the Problems] In order to achieve the above object, the steps of gas chromatograph analysis are performed by setting analysis parameters, analysis, determination of completion of all analysis, column oven temperature change (constant temperature below initial temperature), Divide like changing the column oven temperature (set to the initial temperature).

First, before the analysis is started, the analysis parameters are set, and the conditions for ending the whole analysis, the temperature below the initial temperature to be held at the end of the whole analysis, and the holding time are set. Next, the analysis is performed. At the same time as the end, according to the condition set in, the all-analysis end determination mechanism works, and if all the analysis is not completed, the analysis is repeated, and if all the analysis is completed,
The column oven temperature is changed (set to a constant temperature below the initial temperature) for the time set in, and then the column oven temperature is changed (set to the initial temperature), and the next preparation for analysis is performed.

[0008]

[Function] By referring to the analysis parameters such as all analysis end conditions set before the start of analysis, every time one analysis is completed, the mechanism for determining the end of all analysis operates, and if all the analysis is not completed, the analysis is repeated and all When the analysis is completed, the temperature of the column oven is kept at a constant temperature below the initial temperature for a certain period of time to extend the life of the analytical column.

[0009]

Embodiments of the present invention will be described with reference to FIGS. 1, 2, 3 and 4.

FIG. 1 is a system diagram of a gas chromatograph according to the present invention. 1 is a column oven, 2 is an analysis column, 3 is a sample injection part, 4 is a flow rate control part, 5 is a detection part, 6
Is a main control unit, 7 is an all-analysis end determination mechanism, and 8 is an analysis parameter storage.

Analysis parameters such as all analysis end conditions set before the start of analysis are stored in the analysis parameter storage 8. Every time one analysis is completed, the data in the analysis parameter storage 8 is referred to, and the all-analysis end determination mechanism 7 operates. As a result, if the analysis is not completed yet, the analysis is repeated. If the analysis is completed, the temperature of the one-column oven in which the analysis column 2 is stored is maintained at a constant temperature below the initial temperature for a certain period of time.

FIGS. 2 and 3 show an embodiment of the mechanism for determining the end of all 7 analyzes.

First, FIG. 2 shows an example in which the all-analysis end determination mechanism operates based on the number of times of analysis. Reference numeral 20 is an analysis preparation, and 21 is an analysis parameter setting. As the analysis parameters, the required number of analyzes, the holding temperature of the column oven after the completion of all the analysis (a temperature lower than the initial temperature) and the holding time at this temperature are input. 22 is a judgment as to whether or not the whole analysis is completed. The determination is made based on whether or not the remaining analysis number (difference between the required analysis number input as the analysis parameter in 21 and the actual analysis number) is zero. 23 if the number of remaining analyzes is not 0
If the analysis is repeated and the value is 0, the column oven temperature is set at 24 to the column oven holding temperature (lower than the initial temperature) after the completion of all the analysis entered at 21. 25 is 24
It is a judgment whether to continue the holding temperature changed in
This temperature is held until the holding time input in 21 elapses. When the holding time has elapsed, the temperature of the column oven is returned to the initial temperature at 26 to prepare for the next analysis.

Next, FIG. 3 shows an example in which the all-analysis end determination mechanism operates according to the actual time. 30 is an analysis preparation, 31 is an analysis parameter setting, and the current time, the total analysis end time, the holding temperature (lower than the initial temperature) of the column oven after the completion of all the analysis, and the holding time at this temperature are input as the analysis parameters. To do. 32 is a judgment as to whether or not the whole analysis is completed. The determination is made by whether or not the total analysis end time input in 31 is reached. If the total analysis end time has not been reached, 33 analyzes are repeated. If the total analysis end time has been reached, the column oven temperature entered at 34 is the column oven holding temperature after the end of all analyzes (from the initial temperature Low temperature). Reference numeral 35 is a determination as to whether or not to continue the holding temperature changed in 34, and this temperature is held until the holding time input in 31 elapses. When the holding time has passed, the temperature of the column oven is returned to the initial temperature at 36 to prepare for the next analysis.

FIG. 4 shows an example of a change pattern of the temperature of a column oven according to the present invention (an example of a temperature rising program with one stage). 40 is the initial temperature, 41 is the analysis end temperature, 4
2 is the holding temperature after the completion of all analyzes (temperature lower than the initial temperature) input as analysis parameters, 43 is the final analysis start point, 44 is the final analysis end point, 45 is the final analysis time, 4
6 is a cooling time after the end of analysis, and 47 is a time for holding 42 input as an analysis parameter. After the end of the final analysis, after a cooling time of 46, a holding temperature of 42 was reached and 4
After the retention time of 7, the column oven temperature returns to the initial temperature and the next analysis preparation is performed.

[0016]

【The invention's effect】

(B) New function According to the analysis parameters set before starting analysis, the life of the analytical column can be automatically extended.

(B) Improvement of performance and efficiency By extending the life of the analytical column, stable data can be obtained for a long period of time.

By extending the life of the analytical column, the number of times the analytical column is replaced can be reduced and the analytical efficiency is greatly improved.

(C) Economical efficiency and simplification By extending the life of the analytical column, the cost of packing materials can be greatly reduced. By extending the life of the analytical column, the number of filling operations of packing material can be greatly reduced.

[Brief description of drawings]

FIG. 1 is a configuration diagram of the present invention.

FIG. 2 is a flow chart of the present invention.

FIG. 3 is a flow chart of the present invention.

FIG. 4 is a diagram showing an example of a change pattern of column oven temperature in the present invention.

[Explanation of symbols]

DESCRIPTION OF SYMBOLS 1 ... Column oven, 2 ... Analysis column, 3 ... Sample injection part, 4 ... Flow control part, 5 ... Detection part, 6 ... Main control part, 7 ...
All-analysis end determination mechanism, 8 ... Analysis parameter storage, 20
... analysis preparation, 21 ... analysis parameter setting, 22 ... all analysis end determination, 23 ... analysis, 24 ... column oven temperature change, 25 ... holding time end determination, 26 ... column oven temperature change, 30 ... analysis preparation, 31 ... analysis parameter settings,
32 ... All analysis end judgment, 33 ... Analysis, 34 ... Column oven temperature change, 35 ... Holding time end judgment, 36 ... Column oven temperature change, 40 ... Initial temperature, 41 ... Analysis end temperature, 42 ... After completion of all analysis Holding temperature (temperature below initial temperature), 43 ... Final analysis start point, 44 ... Final analysis end point, 45 ... Final analysis time, 46 ... Cooling time after analysis, 47 ... Holding time at temperature 42.

Claims (1)

[Claims] 1. A gas chromatograph comprising a column oven, an analytical column, a sample injection unit, a flow rate control unit, a detection unit, a main control unit, a mechanism for judging the end of all analyzes, and the like.
A gas chromatograph characterized by automatically maintaining the temperature of the column oven at a temperature lower than the initial temperature for a certain period of time at the end of all analysis by the analytical column.