JPH0598202A - Ultraviolet-coloring ink composition for skin marking - Google Patents
Ultraviolet-coloring ink composition for skin markingInfo
- Publication number
- JPH0598202A JPH0598202A JP25752391A JP25752391A JPH0598202A JP H0598202 A JPH0598202 A JP H0598202A JP 25752391 A JP25752391 A JP 25752391A JP 25752391 A JP25752391 A JP 25752391A JP H0598202 A JPH0598202 A JP H0598202A
- Authority
- JP
- Japan
- Prior art keywords
- solvent
- ink composition
- soluble
- resin
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 26
- 238000004040 coloring Methods 0.000 title claims description 5
- 239000011347 resin Substances 0.000 claims abstract description 25
- 229920005989 resin Polymers 0.000 claims abstract description 25
- 239000002904 solvent Substances 0.000 claims abstract description 24
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 13
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 11
- 238000001035 drying Methods 0.000 claims abstract description 8
- 235000019441 ethanol Nutrition 0.000 claims abstract description 8
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 10
- 239000000126 substance Substances 0.000 claims description 5
- 230000002087 whitening effect Effects 0.000 claims description 2
- CNGYZEMWVAWWOB-VAWYXSNFSA-N 5-[[4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl]amino]-2-[(e)-2-[4-[[4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl]amino]-2-sulfophenyl]ethenyl]benzenesulfonic acid Chemical compound N=1C(NC=2C=C(C(\C=C\C=3C(=CC(NC=4N=C(N=C(NC=5C=CC=CC=5)N=4)N(CCO)CCO)=CC=3)S(O)(=O)=O)=CC=2)S(O)(=O)=O)=NC(N(CCO)CCO)=NC=1NC1=CC=CC=C1 CNGYZEMWVAWWOB-VAWYXSNFSA-N 0.000 abstract description 6
- 239000003963 antioxidant agent Substances 0.000 abstract description 2
- 230000003078 antioxidant effect Effects 0.000 abstract description 2
- 239000004014 plasticizer Substances 0.000 abstract description 2
- 239000002562 thickening agent Substances 0.000 abstract description 2
- 239000006097 ultraviolet radiation absorber Substances 0.000 abstract 1
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 9
- 239000006081 fluorescent whitening agent Substances 0.000 description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 238000002156 mixing Methods 0.000 description 6
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 5
- 230000000740 bleeding effect Effects 0.000 description 5
- 238000003756 stirring Methods 0.000 description 5
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical class CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 4
- 229920001800 Shellac Polymers 0.000 description 4
- 206010040880 Skin irritation Diseases 0.000 description 4
- 229920002037 poly(vinyl butyral) polymer Polymers 0.000 description 4
- 239000004208 shellac Substances 0.000 description 4
- ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 description 4
- 229940113147 shellac Drugs 0.000 description 4
- 235000013874 shellac Nutrition 0.000 description 4
- 230000036556 skin irritation Effects 0.000 description 4
- 231100000475 skin irritation Toxicity 0.000 description 4
- RSWGJHLUYNHPMX-UHFFFAOYSA-N Abietic-Saeure Natural products C12CCC(C(C)C)=CC2=CCC2C1(C)CCCC2(C)C(O)=O RSWGJHLUYNHPMX-UHFFFAOYSA-N 0.000 description 3
- 239000001856 Ethyl cellulose Substances 0.000 description 3
- KHPCPRHQVVSZAH-HUOMCSJISA-N Rosin Natural products O(C/C=C/c1ccccc1)[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KHPCPRHQVVSZAH-HUOMCSJISA-N 0.000 description 3
- 229920001577 copolymer Polymers 0.000 description 3
- 229920001249 ethyl cellulose Polymers 0.000 description 3
- 235000019325 ethyl cellulose Nutrition 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 3
- 150000002576 ketones Chemical class 0.000 description 3
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical class C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 description 3
- KHPCPRHQVVSZAH-UHFFFAOYSA-N trans-cinnamyl beta-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OCC=CC1=CC=CC=C1 KHPCPRHQVVSZAH-UHFFFAOYSA-N 0.000 description 3
- 229940058015 1,3-butylene glycol Drugs 0.000 description 2
- JXTZQOUZDLZDKS-UHFFFAOYSA-N 2,2,6-trimethyl-1h-pyridine Chemical class CC1=CC=CC(C)(C)N1 JXTZQOUZDLZDKS-UHFFFAOYSA-N 0.000 description 2
- CFNMUZCFSDMZPQ-GHXNOFRVSA-N 7-[(z)-3-methyl-4-(4-methyl-5-oxo-2h-furan-2-yl)but-2-enoxy]chromen-2-one Chemical compound C=1C=C2C=CC(=O)OC2=CC=1OC/C=C(/C)CC1OC(=O)C(C)=C1 CFNMUZCFSDMZPQ-GHXNOFRVSA-N 0.000 description 2
- 235000005811 Viola adunca Nutrition 0.000 description 2
- 240000009038 Viola odorata Species 0.000 description 2
- 235000013487 Viola odorata Nutrition 0.000 description 2
- 235000002254 Viola papilionacea Nutrition 0.000 description 2
- XJHABGPPCLHLLV-UHFFFAOYSA-N benzo[de]isoquinoline-1,3-dione Chemical class C1=CC(C(=O)NC2=O)=C3C2=CC=CC3=C1 XJHABGPPCLHLLV-UHFFFAOYSA-N 0.000 description 2
- 235000019437 butane-1,3-diol Nutrition 0.000 description 2
- WERYXYBDKMZEQL-UHFFFAOYSA-N butane-1,4-diol Chemical compound OCCCCO WERYXYBDKMZEQL-UHFFFAOYSA-N 0.000 description 2
- 150000004775 coumarins Chemical class 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- YPFDHNVEDLHUCE-UHFFFAOYSA-N propane-1,3-diol Chemical compound OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 description 2
- 238000001959 radiotherapy Methods 0.000 description 2
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 description 2
- 125000001834 xanthenyl group Chemical class C1=CC=CC=2OC3=CC=CC=C3C(C12)* 0.000 description 2
- ZWVMLYRJXORSEP-UHFFFAOYSA-N 1,2,6-Hexanetriol Chemical compound OCCCCC(O)CO ZWVMLYRJXORSEP-UHFFFAOYSA-N 0.000 description 1
- RWLALWYNXFYRGW-UHFFFAOYSA-N 2-Ethyl-1,3-hexanediol Chemical compound CCCC(O)C(CC)CO RWLALWYNXFYRGW-UHFFFAOYSA-N 0.000 description 1
- KXGFMDJXCMQABM-UHFFFAOYSA-N 2-methoxy-6-methylphenol Chemical compound [CH]OC1=CC=CC([CH])=C1O KXGFMDJXCMQABM-UHFFFAOYSA-N 0.000 description 1
- 239000004925 Acrylic resin Substances 0.000 description 1
- 229920000178 Acrylic resin Polymers 0.000 description 1
- ZTQSAGDEMFDKMZ-UHFFFAOYSA-N Butyraldehyde Chemical compound CCCC=O ZTQSAGDEMFDKMZ-UHFFFAOYSA-N 0.000 description 1
- 239000000020 Nitrocellulose Chemical class 0.000 description 1
- ALQSHHUCVQOPAS-UHFFFAOYSA-N Pentane-1,5-diol Chemical compound OCCCCCO ALQSHHUCVQOPAS-UHFFFAOYSA-N 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- 239000005456 alcohol based solvent Substances 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 238000005282 brightening Methods 0.000 description 1
- OWBTYPJTUOEWEK-UHFFFAOYSA-N butane-2,3-diol Chemical compound CC(O)C(C)O OWBTYPJTUOEWEK-UHFFFAOYSA-N 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 229920002678 cellulose Chemical class 0.000 description 1
- 239000001913 cellulose Chemical class 0.000 description 1
- 229920002301 cellulose acetate Polymers 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- HOSFCSQXJQXSIQ-ZPZFBZIMSA-L disodium;5-[(4,6-dianilino-1,3,5-triazin-2-yl)amino]-2-[(e)-2-[4-[(4,6-dianilino-1,3,5-triazin-2-yl)amino]-2-sulfonatophenyl]ethenyl]benzenesulfonate Chemical compound [Na+].[Na+].C=1C=C(\C=C\C=2C(=CC(NC=3N=C(NC=4C=CC=CC=4)N=C(NC=4C=CC=CC=4)N=3)=CC=2)S([O-])(=O)=O)C(S(=O)(=O)[O-])=CC=1NC(N=C(NC=1C=CC=CC=1)N=1)=NC=1NC1=CC=CC=C1 HOSFCSQXJQXSIQ-ZPZFBZIMSA-L 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229960005082 etohexadiol Drugs 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- 150000002689 maleic acids Chemical class 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 229920001220 nitrocellulos Chemical class 0.000 description 1
- 150000007965 phenolic acids Chemical class 0.000 description 1
- 229920001568 phenolic resin Polymers 0.000 description 1
- 239000005011 phenolic resin Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 230000009430 psychological distress Effects 0.000 description 1
- 150000003219 pyrazolines Chemical class 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- -1 styrene-maleic acid ester Chemical class 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Radiation-Therapy Devices (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
Abstract
Description
【０００１】[0001]
【産業上の利用分野】本発明は、スキンマーク用紫外線
発色性インキ組成物に関する。FIELD OF THE INVENTION The present invention relates to an ultraviolet coloring ink composition for skin marks.
【０００２】本明細書において、“％”および“部”と
あるのは、それぞれ“重量％”および“重量部”を意味
するものとする。In this specification, the terms "%" and "parts" mean "wt%" and "parts by weight", respectively.
【０００３】[0003]
【従来技術】悪性腫瘍等の放射線治療において、治療計
画によって設定された部位に正しく照射を行うために、
可視光で見える皮膚インキ、シール貼付等による皮膚へ
のマーキング法が用いられている。これらの方法は、比
較的安価で判りやすいが、特に頭頸部の照射をする場合
等には、皮膚に付けられたマークが人目につくため、患
者にとっては精神的に非常に苦痛となるという問題があ
る。2. Description of the Related Art In radiotherapy for malignant tumors, etc., in order to correctly irradiate a site set by a treatment plan,
A marking method is used on the skin such as skin ink visible with visible light and sticking of stickers. These methods are relatively inexpensive and easy to understand, but especially when irradiating the head and neck, the marks on the skin are noticeable, which makes the patient mentally very painful. There is.
【０００４】かかる問題を解決するために、可視光では
見えず、紫外線の照射によって発色するスキンマーク用
インキとして、コニカＸ−レイ写真研究No.201/Vol.42N
o.2(1991)P.60-62にVICTOREEN 社より市販されている蛍
光マーカーキット17-800型で用いるスキンマーク用紫外
線発色性インキが記載されている。しかし、このインキ
組成物には、皮膚上でのニジミが顕著でマークが判りに
くくなるという問題点がある。この問題点の原因は、固
着剤として働く樹脂が配合されていないためと考えられ
る。In order to solve such a problem, Konica X-Ray Photographic Research No. 201 / Vol. 42N is used as a skin mark ink which is invisible to visible light and develops color upon irradiation with ultraviolet rays.
o.2 (1991) P.60-62 describes UV coloring ink for skin mark used in the fluorescent marker kit 17-800 type commercially available from VICTOREEN. However, this ink composition has a problem in that bleeding on the skin is remarkable and the mark is difficult to see. It is considered that the cause of this problem is that the resin acting as a fixing agent is not mixed.
【０００５】[0005]
【発明が解決しようとする課題】本発明は、毒性や皮膚
刺激性がなく、皮膚上でのニジミが無く、かつ皮膚に対
する付着性に優れたスキンマーク用紫外線発色性インキ
組成物を提供することを主な目的とする。DISCLOSURE OF THE INVENTION The present invention provides an ultraviolet color-forming ink composition for skin marks which has neither toxicity nor skin irritation, has no blurring on the skin, and has excellent adhesion to the skin. Is the main purpose.
【０００６】[0006]
【課題を解決するための手段】本発明者は、上記の如き
従来技術の現状に鑑みて鋭意研究を重ねた結果、特定の
溶剤を用い、かつ該溶剤に溶解し、水に溶解しない蛍光
増白剤および樹脂を配合することにより、上記目的を達
成し得ることを見出した。Means for Solving the Problems As a result of intensive studies in view of the above-mentioned conventional state of the art, the present inventor has used a specific solvent and is soluble in the solvent, and is not soluble in water. It has been found that the above object can be achieved by blending a whitening agent and a resin.
【０００７】すなわち、本発明は、スキンマーク用紫外
線発色性インキ組成物であって、（１）エチルアルコー
ル、イソプロピルアルコール及びノルマルプロピルアル
コールの少なくとも一種の溶剤、（２）該溶剤に溶解
し、水に溶解しない蛍光増白剤、および（３）該溶剤に
溶解し、水に溶解しない樹脂を必須成分として含有する
インキ組成物を提供するものである。That is, the present invention relates to an ultraviolet color-forming ink composition for skin marks, which comprises (1) at least one solvent of ethyl alcohol, isopropyl alcohol and normal propyl alcohol, and (2) water dissolved in the solvent. And (3) an ink composition containing, as an essential component, a fluorescent whitening agent that does not dissolve in water, and (3) a resin that dissolves in the solvent but does not dissolve in water.
【０００８】本発明で使用する溶剤は、本発明組成物の
他の必須成分である蛍光増白剤および樹脂を好適に溶解
し又インキ組成物の媒体として機能するものであり、エ
チルアルコール、イソプロピルアルコール及びノルマル
プロピルアルコールの少なくとも一種又は二種以上を用
いる。これら特定のアルコール溶剤は、揮発性と殺菌消
毒効果を有しており、しかも皮膚刺激性が無いという点
で好ましいものである。The solvent used in the present invention preferably dissolves the fluorescent whitening agent and the resin, which are other essential components of the composition of the present invention, and also functions as a medium of the ink composition, such as ethyl alcohol and isopropyl. At least one type or two or more types of alcohol and normal propyl alcohol are used. These specific alcohol solvents are preferable in that they have volatility and a sterilizing / disinfecting effect, and have no skin irritation.
【０００９】また、本発明組成物で用いる蛍光増白剤
は、紫外線（通常波長約340-380nm 程度）の照射により
発色するものであり、上記溶剤に溶解し、水に溶解しな
いことにより皮膚上でのニジミが無いものである。ま
た、低級アルコールに溶解したときに無色又は淡色透明
であり、皮膚刺激性がないものが好ましく、具体例とし
ては、クマリン誘導体、ピラゾリン誘導体、スチルベン
誘導体、ビスベンゾオキサゾリル誘導体、ナフタルイミ
ド誘導体、キサンテン誘導体、トリメチルジヒドロピリ
ジン誘導体、コエロキセン誘導体等を挙げることができ
る。これらのうち、より好ましいものは、クマリン誘導
体、スチルベン誘導体、ビスベンゾオキサゾリル誘導体
等である。Further, the fluorescent whitening agent used in the composition of the present invention develops a color upon irradiation with ultraviolet rays (usually a wavelength of about 340 to 380 nm). There is no bleeding in. Further, those which are colorless or pale transparent when dissolved in a lower alcohol and which are not skin irritating are preferable, and specific examples include coumarin derivatives, pyrazoline derivatives, stilbene derivatives, bisbenzoxazolyl derivatives, naphthalimide derivatives, Examples thereof include xanthene derivatives, trimethyldihydropyridine derivatives, coeloxene derivatives and the like. Among these, more preferred are coumarin derivatives, stilbene derivatives, bisbenzoxazolyl derivatives and the like.
【００１０】本発明インキ組成物においては、上記溶剤
に溶解し、水に溶解しないことにより皮膚上でのニジミ
が防止できる樹脂を配合する。かかる油溶性樹脂として
は、皮膚刺激性が無く、溶解性に優れ、無色又は淡色
で、耐水性に優れるものが好ましく、具体例としてはエ
チルセルロース、ニトロセルロース、セルロースアセテ
ート等のセルロース誘導体、マレイン酸樹脂、ロジン変
性マレイン酸樹脂、スチレン−マレイン酸エステルコポ
リマー等のマレイン酸系樹脂、アルキルフェノール樹
脂、ロジン変性フェノール酸樹脂等のフェノール系樹
脂、ポリビニルブチラール、アルコール溶性ポリアミ
ド、シェラック、アクリル樹脂、ロジン、ケトン樹脂等
を挙げることができる。これらのうち、より好ましいも
のは、超淡色ロジン、ポリビニルブチラール、シェラッ
ク、エチルセルロース、スチレン−マレイン酸エステル
コポリマー、ケトン樹脂等である。In the ink composition of the present invention, a resin is added which is soluble in the above-mentioned solvent but is not soluble in water so that bleeding on the skin can be prevented. As the oil-soluble resin, those having no skin irritation, excellent solubility, colorless or pale color, and excellent in water resistance are preferable, and specific examples thereof include ethyl cellulose, nitrocellulose, cellulose derivatives such as cellulose acetate, and maleic acid resins. , Rosin-modified maleic acid resin, styrene-maleic acid ester maleic resin, etc., alkylphenol resin, rosin-modified phenolic acid resin and other phenolic resin, polyvinyl butyral, alcohol-soluble polyamide, shellac, acrylic resin, rosin, ketone resin Etc. can be mentioned. Among these, more preferable are ultra-light color rosin, polyvinyl butyral, shellac, ethyl cellulose, styrene-maleic acid ester copolymer, and ketone resin.
【００１１】本発明インキ組成物における上記三種の必
須成分の配合割合は、特に限定されることなく広い範囲
から選択できるが、油溶性樹脂１００部に対して、上記
溶剤を２００〜２００００部程度、好ましくは６００〜
１００００部程度が、上記蛍光増白剤を１〜２０００部
程度、好ましくは２〜５００部程度が、夫々適当であ
る。溶剤が上記範囲より少ない場合（上記樹脂が多い場
合）には経時安定性が低下して増粘する傾向があり、又
多い場合（上記樹脂が少ない場合）には皮膚上でニジミ
が発生したり皮膚上での付着性が低下したりする傾向に
あるので好ましくない。また、蛍光増白剤が上記範囲よ
り少ない場合や多い場合にはいずれにおいても発色性が
低下する傾向にあるので好ましくない。The mixing ratio of the above-mentioned three essential components in the ink composition of the present invention is not particularly limited and can be selected from a wide range, but about 200 to 20,000 parts of the above solvent to 100 parts of the oil-soluble resin, Preferably 600-
Approximately 10000 parts, about 1 to 2000 parts, preferably about 2 to 500 parts, of the above-mentioned fluorescent whitening agent are suitable. When the amount of solvent is less than the above range (when the amount of the above resin is large), stability over time tends to decrease and the viscosity tends to increase. When the amount of solvent is large (when the amount of the above resin is small), bleeding may occur on the skin. It is not preferable because the adhesion on the skin tends to decrease. Further, when the amount of the fluorescent whitening agent is smaller or larger than the above range, the color developability tends to decrease in any case, which is not preferable.
【００１２】本発明インキ組成物においては、必要に応
じて、乾燥速度調節剤を更に配合することができる。該
調節剤を配合することにより、キャップオフ性等を向上
させることができる。本発明で用いる乾燥速度調節剤と
しては、低級アルコールに溶解し、揮発性があり、皮膚
刺激性がないものが好ましく、具体例としては、プロピ
レングリコール、トリメチレングリコール、１，３−ブ
チレングリコール、テトラメチレングリコール、２，３
−ブチレングリコール、ペンタメチレングリコール、オ
クチレングリコール、グリセリン、１，２，６−ヘキサ
ントリオール等を挙げることができる。これらのうち、
より好ましいものは、プロピレングリコール、１，３−
ブチレングリコール、グリセリン等である。乾燥速度調
節剤を用いる場合の配合量は、特に限定されないが、油
溶性樹脂１００部に対して、２〜６０００部程度、好ま
しくは１０〜２０００部程度が適当である。In the ink composition of the present invention, a drying rate adjusting agent can be further added, if necessary. By blending the regulator, the cap-off property and the like can be improved. As the drying rate regulator used in the present invention, those which are soluble in a lower alcohol, are volatile and have no skin irritation are preferable, and specific examples thereof include propylene glycol, trimethylene glycol, 1,3-butylene glycol, Tetramethylene glycol, 2,3
-Butylene glycol, pentamethylene glycol, octylene glycol, glycerin, 1,2,6-hexanetriol and the like can be mentioned. Of these,
More preferred are propylene glycol and 1,3-
Examples include butylene glycol and glycerin. The amount of the drying rate regulator used is not particularly limited, but is appropriately about 2 to 6000 parts, preferably about 10 to 2000 parts, relative to 100 parts of the oil-soluble resin.
【００１３】更に、本発明インキ組成物には、任意成分
として、可塑剤、紫外線吸収剤、増粘剤、酸化防止剤、
増感剤、レベリング剤、溶解助剤、アルコール溶性染
料、香料、界面活性剤、防腐剤等を、適宜添加すること
ができる。Further, in the ink composition of the present invention, as an optional component, a plasticizer, a UV absorber, a thickener, an antioxidant,
A sensitizer, a leveling agent, a solubilizing agent, an alcohol-soluble dye, a fragrance, a surfactant, an antiseptic and the like can be appropriately added.
【００１４】本発明のスキンマーク用紫外線発色性イン
キ組成物は、通常のインキ組成物と同様の方法により、
好適に調製することができる。例えば、通常の撹拌容器
を用い、上記溶剤に、上記樹脂、蛍光増白剤及び必要に
応じて乾燥速度調節剤を、任意の順序で又は同時に、撹
拌下で好ましくは加温下に、適宜の時間混合溶解して、
インキ組成物を調製すれば良い。この際、組成物の粘度
は、通常５０cp以下程度、好ましくは５０〜２cp程度と
するのが、インキ流出性をスムースにする点から望まし
い。The UV color-forming ink composition for skin marks of the present invention is prepared in the same manner as a conventional ink composition.
It can be suitably prepared. For example, using a normal stirring container, in the solvent, the resin, the fluorescent whitening agent and optionally a drying rate adjusting agent, in any order or simultaneously, under stirring, preferably under heating, appropriate Mix and dissolve for hours,
An ink composition may be prepared. At this time, the viscosity of the composition is usually about 50 cp or less, preferably about 50 to 2 cp, from the viewpoint of smoothing the ink outflow property.
【００１５】本発明インキ組成物を適用する筆記用具と
しては、特に限定はなく、通常の用具をいずれも適用で
きる。特に好ましい具体例としては、作業性が良く、一
定の筆記線が得られ、かつ使用目的に応じた線巾を設定
でき、マーキングの精度が良い、繊維束チップをペン先
とするものを挙げることができる。The writing instrument to which the ink composition of the present invention is applied is not particularly limited, and any ordinary instrument can be applied. Particularly preferred specific examples include those having a good workability, a certain writing line can be obtained, a line width can be set according to the purpose of use, a marking accuracy is good, and a fiber bundle tip is used as a pen tip. You can
【００１６】[0016]
【発明の効果】本発明のスキンマーク用紫外線発色性イ
ンキ組成物は、無色又は淡色透明であるため、可視光下
では皮膚にマークした部位が見えないが、紫外線（通常
波長約３４０〜３８０nm付近）を吸収し、その吸収エネ
ルギーを約４３０〜４４０nm付近の可視部で蛍光発色す
るため、放射線治療時のブラックランプ照射時のみマー
クが確認できる。また、水不溶性の蛍光増白剤及び樹脂
を配合しているので、皮膚への付着性及び耐水性、耐汗
性が良好となり、従来品に見られるようなニジミが全く
無い。従って、本発明インキ組成物により、放射線治療
患者の精神的苦痛が大巾に軽減される。EFFECTS OF THE INVENTION The UV-coloring ink composition for skin marks of the present invention is colorless or light-color transparent, and therefore, the marked portion on the skin cannot be seen under visible light, but the UV-ray (usually a wavelength of about 340 to 380 nm is around. ) Is absorbed and the absorbed energy emits fluorescence in the visible region around 430 to 440 nm, so that the mark can be confirmed only during irradiation with a black lamp during radiation treatment. In addition, since a water-insoluble fluorescent whitening agent and a resin are blended, the adhesion to the skin, the water resistance and the sweat resistance are improved, and there is no bleeding as seen in conventional products. Therefore, the ink composition of the present invention greatly reduces the psychological distress of a radiation therapy patient.
【００１７】[0017]
【実施例】以下に実施例を示し、本発明の特徴とすると
ころをより一層明確にする。実施例で使用した各成分の
具体的内容は、下記の通りである。EXAMPLES Examples will be shown below to further clarify the features of the present invention. The specific contents of each component used in the examples are as follows.
【００１８】Ａ 蛍光増白剤 Ａ−１…Ｃ．Ｉ．フルオリーセント ブライトナー ９
１（クマリン誘導体、“カヤライトＢ”、日本化薬
（株）製） Ａ−２…Ｃ．Ｉ．フルオリーセント ブライトナー １
２８（スチルベン誘導体、“ヒルタミン アークティッ
ク ホワイト ＤＭＬ”、ヒルトン−デイビスケミカル
社（米）製） Ａ−３…Ｃ．Ｉ．フルオリーセント ブライトナー １
７０（ビスベンゾオキサゾリル誘導体、“ミケファー
ＥＮ”、三井東圧化学（株）製） Ａ−４…Ｃ．Ｉ．フルオリーセント ブライトナー ７
６（ナフタルイミド誘導体、“フルオロール ＯＢ”、
ＧＡＦ コーポレーション（米）製） Ａ−５…Ｃ．Ｉ．フルオリーセント ブライトナー ７
４（キサンテン誘導体、“フルオロール ５Ｇ”、Ｉ．
Ｇ．ファーベ インダストリー（独）製） Ａ−６…Ｃ．Ｉ．フルオリーセント ブライトナー ７
３（トリメチルジヒドロピリジン誘導体、“ブランコー
ル ＳＳ”、Ｌ．Ｂ．ホリディ ＆ Ｃｏ．（英）製） Ａ−７…Ｃ．Ｉ．フルオリーセント ブライトナー １
５５（コエロキセン誘導体、“フルオリーセント グリ
ーン ＨＷ”、ウイルモット ＆ カシディ社（米）
製） Ａ−８…Ｃ．Ｉ．フルオリーセント ブライトナー ２
０３（クマリン誘導体、“ブランコフォー ＫＬ”、バ
イエル社（独）製） Ｂ 油溶性樹脂 Ｂ−１…ポリビニルブチラール（“デンカブチラール２
０００−Ｌ”、電気化学工業（株）製） Ｂ−２…超淡色ロジン（“ＫＰ−６１０”、荒川化学工
業（株）製） Ｂ−３…シェラック（乾燥透明白ラック、日本シェラッ
ク工業（株）製） Ｂ−４…スチレン−マレイン酸エステルコポリマー
（“スプラパールＡＰ２０”、ＢＡＳＦ ＡＧ（独）
製） Ｂ−５…エチルセルロース（“エトセル１０”、ダウ
ケミカル社（米）製） Ｂ−６…ポリビニルブチラール（“エスレックＢＬ−
Ｓ”、積水化学工業（株）製） Ｂ−７…ケトン樹脂（“ハイラック１１０Ｈ”、日立化
成工業（株）製） Ｂ−８…スチレン−マレイン酸エステルコポリマー
（“スプラパールＡＰ３０”、ＢＡＳＦ ＡＧ（独）
製） Ｃ 乾燥速度調節剤 Ｃ−１…プロピレングリコール Ｃ−２…グリセリン Ｃ−３…１，３−ブチレングリコール Ｄ 溶剤 Ｄ−１…エチルアルコール Ｄ−２…イソプロピルアルコール Ｄ−３…ノルマルプロピルアルコールA optical brightener A-1 ... C. I. Fluorescent Brightener 9
1 (coumarin derivative, “Kayalite B”, manufactured by Nippon Kayaku Co., Ltd.) A-2 ... C.I. I. Fluorescent Saint Brightener 1
28 (stilbene derivative, "Hirtamine Arctic White DML", manufactured by Hilton-Davis Chemical Company (US)) A-3 ... C.I. I. Fluorescent Saint Brightener 1
70 (bisbenzoxazolyl derivative, "Mike fur
EN ", manufactured by Mitsui Toatsu Chemicals, Inc. A-4 ... CI Fluorescent Brightener 7
6 (Naphthalimide derivative, "Fluorol OB",
GAF Corporation (US) A-5 ... C. I. Fluorescent Brightener 7
4 (xanthene derivative, "Fluorol 5G", I.V.
G. Fervey Industry (Germany) A-6 ... C. I. Fluorescent Brightener 7
3 (trimethyldihydropyridine derivative, “Blankol SS”, manufactured by LB Holiday & Co. (UK)) A-7 ... C.I. I. Fluorescent Saint Brightener 1
55 (Coeloxene derivative, "Fluorescent Green HW", Wilmot & Cassidy (US)
A-8 ... C. I. Fluorescent Brightener 2
03 (coumarin derivative, "Brancophor KL", manufactured by Bayer (Germany)) B oil-soluble resin B-1 ... Polyvinyl butyral ("Denka butyral 2"
000-L ", manufactured by Denki Kagaku Kogyo Co., Ltd. B-2 ... Ultra-light color rosin (" KP-610 ", manufactured by Arakawa Chemical Industry Co., Ltd.) B-3 ... Shellac (dry transparent white rack, Nippon Shellac Industry ( B-4 ... Styrene-maleic acid ester copolymer (“Suprapearl AP20”, BASF AG (Germany))
B-5 ... Ethylcellulose (“Ethocel 10”, Dow)
Made by Chemical Company (US) B-6 ... Polyvinyl butyral (“S-REC BL-
S ", Sekisui Chemical Co., Ltd. B-7 ... Ketone resin (" Hirac 110H ", Hitachi Chemical Co., Ltd.) B-8 ... Styrene-maleic acid ester copolymer (" Suprapearl AP30 ", BASF AG) (Germany)
C) Drying speed regulator C-1 ... Propylene glycol C-2 ... Glycerin C-3 ... 1,3-butylene glycol D Solvent D-1 ... Ethyl alcohol D-2 ... Isopropyl alcohol D-3 ... Normal propyl alcohol
【００１９】[0019]
【実施例１〜８】下記第１表に示す割合（部）で各成分
を配合し、インキ組成物を調製した。配合は、Ｄ成分
（溶剤）に、Ｂ成分（油溶性樹脂）を加えて６０℃で３
０分間撹拌、混合し、次にＡ成分（蛍光増白剤）を加え
て６０℃で３０分間攪拌、混合し、更にＣ成分（乾燥速
度調節剤）を撹拌下に適宜加えることにより、行った。Examples 1 to 8 Ink compositions were prepared by mixing the components in the proportions (parts) shown in Table 1 below. The compounding is done by adding the B component (oil-soluble resin) to the D component (solvent) at 3 ° C at 60 ° C.
Stirring and mixing for 0 minutes, then adding component A (optical brightening agent) and stirring at 60 ° C. for 30 minutes, mixing, and further appropriately adding component C (drying speed controller) with stirring. ..
【００２０】 第 １ 表 発色（紫外 実施例 Ａ Ｂ Ｃ Ｄ 粘度(cp) 線照射時） １ Ａ−１ Ｂ−１ − Ｄ−１ ６ 青紫 ３３ １００ 1667 Ｄ−２ 1533 ２ Ａ−２ Ｂ−２ Ｃ−１ Ｄ−３ ９ 青紫 ５０ １００ ８０ ７７０ ３ Ａ−３ Ｂ−３ − Ｄ−１ ２ 青 １０ １００ ５５７ ４ Ａ−４ Ｂ−４ Ｃ−２ Ｄ−１ ８ 青緑 ５０ １００ ６３ ３７５ Ｄ−３ ６６３ ５ Ａ−５ Ｂ−５ − Ｄ−２ １０ 黄緑 ３５０ １００ 9500 ６ Ａ−６ Ｂ−６ − Ｄ−２ １５ 青 ４ １００ 1333 Ｄ−３ ７８４ ７ Ａ−７ Ｂ−７ Ｃ−３ Ｄ−１ ４０ 緑 １８８ １００ ２１４ 1007 ８ Ａ−８ Ｂ−８ − Ｄ−１ ２２ 青 ２０ １００ ２００ Ｄ−２ ３８０ Ｄ−３ ３００Table 1 Color development (UV Example A B C D Cd (cp) ray irradiation) 1 A-1 B-1-D-1 6 Blue-violet 33 100 1667 D-2 1533 2 A-2 B-2 C-1 D-3 9 Blue-violet 50 100 80 80 770 3 A-3 B-3-D-12 blue 10 100 557 4 A-4 B-4 C-2 D-1 8 blue-green 50 100 63 63 375 D- 3 663 5 A-5 B-5-D-2 10 Yellow Green 350 100 9500 6 A-6 B-6-D-2 15 Blue 4 100 1333 D-3 784 7 A-7 B-7 C-3 D -1 40 Green 188 100 214 1007 8 A-8 B-8-D-1 22 Blue 20 100 200 D-2 380 D-3 300
Claims (2)
であって、（１）エチルアルコール、イソプロピルアル
コール及びノルマルプロピルアルコールの少なくとも一
種の溶剤、（２）該溶剤に溶解し、水に溶解しない蛍光
増白剤、および（３）該溶剤に溶解し、水に溶解しない
樹脂を必須成分として含有するインキ組成物。1. An ultraviolet coloring ink composition for skin marks, which comprises (1) at least one solvent of ethyl alcohol, isopropyl alcohol and normal propyl alcohol, and (2) a fluorescent substance which is soluble in the solvent but is insoluble in water. An ink composition containing, as an essential component, a whitening agent and (3) a resin that is soluble in the solvent but is insoluble in water.
含有する請求項１に記載のインキ組成物。2. The ink composition according to claim 1, which further contains a drying rate adjusting agent which is soluble in the solvent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25752391A JP3032873B2 (en) | 1991-10-04 | 1991-10-04 | Ultraviolet coloring ink composition for skin mark |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25752391A JP3032873B2 (en) | 1991-10-04 | 1991-10-04 | Ultraviolet coloring ink composition for skin mark |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH0598202A true JPH0598202A (en) | 1993-04-20 |
| JP3032873B2 JP3032873B2 (en) | 2000-04-17 |
Family
ID=17307482
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP25752391A Expired - Fee Related JP3032873B2 (en) | 1991-10-04 | 1991-10-04 | Ultraviolet coloring ink composition for skin mark |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3032873B2 (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6013122A (en) * | 1998-08-18 | 2000-01-11 | Option Technologies, Inc. | Tattoo inks |
| CN1049233C (en) * | 1995-10-31 | 2000-02-09 | 潮安县庵埠壮丽印刷有限公司 | Invisible fidelity printing ink and preparation method thereof |
| EP1036129A1 (en) * | 1997-11-07 | 2000-09-20 | OMD Devices LLC | Fluorescent composition for the manufacture of cd-rom type optical memory disks |
| FR2812300A1 (en) * | 2000-07-28 | 2002-02-01 | Cypher Science | SECURE OPTICALLY REVELABLE LIQUID INK AND METHOD OF MARKING PRODUCTS WITH SUCH AN INK |
| US6800122B2 (en) | 1998-11-20 | 2004-10-05 | Freedom-2, Llc | Permanent, removable tissue markings |
-
1991
- 1991-10-04 JP JP25752391A patent/JP3032873B2/en not_active Expired - Fee Related
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1049233C (en) * | 1995-10-31 | 2000-02-09 | 潮安县庵埠壮丽印刷有限公司 | Invisible fidelity printing ink and preparation method thereof |
| EP1036129A1 (en) * | 1997-11-07 | 2000-09-20 | OMD Devices LLC | Fluorescent composition for the manufacture of cd-rom type optical memory disks |
| EP1036129A4 (en) * | 1997-11-07 | 2000-12-27 | Omd Devices Llc | Fluorescent composition for the manufacture of cd-rom type optical memory disks |
| US6013122A (en) * | 1998-08-18 | 2000-01-11 | Option Technologies, Inc. | Tattoo inks |
| US6800122B2 (en) | 1998-11-20 | 2004-10-05 | Freedom-2, Llc | Permanent, removable tissue markings |
| US6814760B2 (en) | 1998-11-20 | 2004-11-09 | The General Hospital Corporation | Permanent, removable tissue markings |
| US6881249B2 (en) | 1998-11-20 | 2005-04-19 | The General Hospital Corporation | Permanent, removable tissue markings |
| US7175950B2 (en) | 1998-11-20 | 2007-02-13 | The General Hospital Corporation | Permanent, removable tissue markings |
| US7285364B2 (en) | 1998-11-20 | 2007-10-23 | The General Hospital Corporation | Permanent, removable tissue markings |
| US7435524B2 (en) | 1998-11-20 | 2008-10-14 | The General Hosptial Corporation | Permanent, removable tissue markings |
| FR2812300A1 (en) * | 2000-07-28 | 2002-02-01 | Cypher Science | SECURE OPTICALLY REVELABLE LIQUID INK AND METHOD OF MARKING PRODUCTS WITH SUCH AN INK |
| WO2002010295A1 (en) * | 2000-07-28 | 2002-02-07 | Cypher Science | Secure optically readable adhesive or coating liquid product, method for marking products with a liquid ink and uses of said product |
Also Published As
| Publication number | Publication date |
|---|---|
| JP3032873B2 (en) | 2000-04-17 |
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