JPH0593678A - Automatic apparatus for preparing blood sample - Google Patents

Abstract

PURPOSE:To make an apparatus small in size and to lower the cost thereof by a construction wherein a rotary plate is disposed on the same plane as a conveyance path surface and a guide frame tube surrounding this rotary plate is made elevatable by an elevating member. CONSTITUTION:A disk 33a is rotated by driving a motor 32 for elevation, and an eccentric projecting shaft 33b pushes down a flat plate part 31. Thereby a guide frame tube 2 is lowered below the height of a conveyance path surface 7 and a rotary plate 11 on the same plane as the path surface 7 is exposed. Meanwhile, a cover plate 23 does not move since it is fixed to a side plate 71 of the path surface 7. Then, the path surface 7 is moved and slide glass A placed on a feeding plate 73 provided in the end part of the path surface 7 is set directly on the rotary plate 11 by the feeding plate 73 being moved until it comes close onto the one end side of the rotary plate 11. Thereafter the frame tube 2 is elevated and returned by an elevating member 3. After blood is dropped on the glass A from a small hole 23a of the cover plate 2 by a dispensing and aliquoting means, a motor 1b for centrifugal smearing is rotated and a centrifugal smearing processing is executed.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an automatic blood sample preparation device.

[0002]

2. Description of the Related Art An automatic blood sample preparation device agitates blood in a blood collection tube by a stirring means and collects blood in the blood collection tube by a dispensing means. The slide glasses are set on the centrifugal smearing means (rotating plate) one by one from the stock. The dispensed blood is dripped on the slide glass set on the rotary plate by the dispensing means. Then, the rotating plate of the centrifugal smearing means is rotated to perform the centrifugal smearing process, and after recording the specific information (for example, print recording) on the slide glass subjected to the centrifugal smearing process, the sample is transferred to the staining process and the blood sample is stained and processed. Create.

[0003]

The centrifugal smearing means of the above-mentioned conventional automatic blood sample preparation apparatus comprises a rotating plate, a guide frame cylinder having an upper opening surrounding the rotating plate, and a centrifugal smearing motor for rotating the rotating plate. It has a main body case. The rotating plate is
Although it is placed at a height position almost the same as the conveying road surface that conveys the slide glasses, the upper peripheral part of the guide frame cylinder that surrounds the rotating plate is fixed to the main body case while protruding slightly above the conveying road surface. is there. In other words, the guide frame tube is used when centrifugally smearing the slide glass set on the rotating plate,
In order to prevent blood from splashing to the surroundings, the structure is such that the upper part is above the slide glass and is bent inward, and surrounds the slide glass. Therefore, as a result of the guide frame tube blocking the conveyance road surface, when setting the slide glass on the rotating plate, it is necessary to move the slide glass up and down by the handling mechanism. In other words, the slide glass is sucked and raised further upward from the upper part of the guide frame cylinder positioned so as to block the transport surface, and is set to the upper surface of the rotating plate through the upper opening of the guide frame cylinder. Therefore, in addition to the transport surface (transport band), a handling mechanism is not required, and a large space for raising and lowering the slide glass is required, which is disadvantageous in that the device becomes large and expensive.

The present invention solves the above problems and allows a slide glass, which is transported on the transport path surface, to be directly set on a rotary plate as it is, which realizes downsizing and cost reduction of the apparatus. It is an object to provide an automatic sample preparation device.

[0005]

In order to achieve this object, in the blood sample automatic preparing apparatus of the present invention,
It has the following configuration. The automatic blood sample preparation device
After stirring the blood in the blood collection tube, dispensed on a slide glass set in the centrifugal smearing means and centrifugally smearing, a device for producing a blood specimen by staining with a staining means, wherein the centrifugal smearing means is: A main body case with a motor for centrifugal smearing, a rotary plate that projects upward from the main body case and is arranged flush with the conveyance path surface, and this rotary plate is surrounded by the upper part and the lower part is externally fitted to the main body case. And a lifting member for moving the guide frame cylinder up and down.

The automatic blood sample preparation device having such a configuration is characterized by the centrifugal smearing means. In other words, the rotating plate of the centrifugal smearing means is arranged flush with the slide glass conveying path surface, and the guide frame cylinder surrounding the rotating plate moves up and down with respect to the rotating plate. Therefore, in the normal state, the guide frame cylinder blocks the conveyance path surface in the state where the rotary plate is housed inside. However, at the stage of setting the slide glass on the rotary plate, that is, when the slide glass is transferred from the slide glass stock toward the rotary plate by the transport road surface (transport belt), the guide frame tube is lowered by the elevating member and the transport road surface The flush rotating plate is exposed. The elevating member has a structure in which, for example, an eccentric cam is provided between the fitting of the guide frame cylinder and the main body case, and the guide frame cylinder is moved up and down with respect to the main body case by rotating the eccentric cam. As a result, as the guide frame cylinder moves up and down, the slide glass is directly pushed out from the conveyance path surface and set on the flush plate. Therefore, the transport mechanism does not have to be a simple structure, and a small device can be provided in a small space.

[0007]

DESCRIPTION OF THE PREFERRED EMBODIMENTS FIG. 1 is a cross-sectional view of essential parts showing a specific embodiment of the blood sample automatic preparation apparatus according to the present invention.

As shown in FIG. 4, the automatic blood sample preparation apparatus has a transport means 61 for transporting a plurality of blood collection tubes 5 housed in a rack, a stirring means 62 for stirring the blood collection tubes 5, and a stirred sample collection tube. A dispensing means 63 for dispensing blood in the blood vessel 5, a stocker 64 for stocking a plurality of slide glasses A,
A transport road surface (transport belt) 7 for transporting the slide glass A from the stocker 64, and a slide glass A provided on the way of transport of the transport road surface 7, set on the rotating plate by the transport road surface 7, and blood collected on the upper surface. Centrifugal smearing means 65 for centrifuging smearing, and printing means 66 for recording specific data read from the blood collection tube 5 by the barcode reader 68 on the slide glass A transported by the transporting road surface 7.
And a dyeing means 67 for dyeing the slide glass A.

A feature of the present invention is that the centrifugal smearing means 65 is used.
In the structure of. The centrifugal smearing means 65 includes a main body case 1 in which the centrifugal smearing motor 1b is installed, a rotary plate 11 projecting upward from the main body case 1 and arranged flush with the transport path surface 7, and the rotary plate 11. The upper part surrounds the lower part, and the lower part is constituted by a guide frame cylinder 2 which is fitted onto the main body case 1, and an elevating member 3 for vertically moving the guide frame cylinder 2.

The main body case 1 is a cylindrical body mounted on a base 1a, and internally has a centrifugal smearing motor 1b installed therein. A rotary shaft 12 of the motor 1b is provided so as to project upward, and a tip end of the rotary shaft 12 is provided. The rotating plate 11 is attached. The rotary plate 11 is set so as to be flush with the height position of the transport road surface 7. The guide frame cylinder 2 is composed of an upper guide cylinder portion 21 and a lower cylinder 22 fixed to the bottom surface of the guide cylinder portion 21 by a shaft 21a. The guide cylinder portion 21 is a cylinder body having an open top,
The bottom surface has a through hole 21b through which the rotary shaft 12 is inserted. The lower cylinder 22 is fitted on the outer wall of the main body case 1 and has a slide portion 22a on the inner surface of the main body case 1 which is fitted to the guide rail 13 of the main body case 1 (see FIG. 2). Furthermore,
A bellows cylinder portion 22b surrounding the rotation shaft 12 is attached to the center of the upper portion of the lower cylinder 22 (a position corresponding to the rotation shaft 12). An upper end of the bellows cylinder 22b is a bottom surface of the guide cylinder portion 21 and a lower end thereof is the main body case 1. It is fastened to the upper surface of. A cover plate 23 is provided on the opening surface of the guide tube portion 21 (upper peripheral edge surrounding the rotary plate 11). This lid plate 23 is
A small hole 23a for dropping blood is provided in the center of the surface, and an outer peripheral edge of the small hole 23a is fixed to the guide side plate 71 of the transport path surface 7 with a screw 72. Further, as shown in FIG. 3, an opening / closing plate 23b for opening and closing the small hole 23a is attached to the upper surface of the lid plate 23 by a spring 23c so as to be movable left and right. The opening / closing plate 23b that opens and closes the small hole 23a can be kept closed by the lock portion 23d. A coil spring 21c is wound around the shaft 21a connecting and fixing the guide cylinder portion 21 and the lower cylinder 22, and is set so that the upper peripheral edge of the guide cylinder portion 21 absorbs the pressure of contacting the lid plate 23. There is.

As shown in FIG. 2, the elevating member 3 includes a flat plate portion 31 attached to the lower end of the outer surface of the lower cylinder 22, and an eccentric cam 33 which is connected to an elevating motor 32 provided in the lower portion of the main body case 1. Consists of. The flat plate portion 31 is the main body case 1
It is arranged in a substantially tangential manner on the outer surface of the, and a long hole 31a is opened in the surface. The eccentric cam 33 is a disc 33a and the protruding shaft 3 eccentrically attached to one end of the disc 33a in the plane.
3b and. The diameter of the protruding shaft 33b is set to be substantially the same as the short diameter of the long hole 31a.
It is projected outward from inside a.

In the centrifugal smearing means 35 of the automatic blood sample preparation apparatus having such a structure, the rotary plate 11 is arranged flush with the slide glass conveying path surface 7 and surrounds the rotary plate 11 with a guide frame cylinder ( The guide tube portion 21) 2 can move up and down with respect to the rotary plate 11. In the normal state, the guide frame cylinder (guide cylinder portion 21) 2 blocks the conveyance road surface 7 with the rotary plate 11 accommodated therein (see FIG. 1). However, at the stage of setting the slide glass A on the rotary plate 11, that is, when the slide glass A is transferred from the slide glass stock 64 toward the rotary plate 11 by the transport road surface 7, the guide frame cylinder 2 is lowered by the elevating member 3. Then, the rotary plate 11 that is flush with the transport path surface 7 is exposed. That is, the disk 32 rotates by driving the lifting motor 32, and the eccentric protruding shaft 33b pushes down the flat plate portion 31.
As a result, the guide frame cylinder 2 is lowered below the height of the transport road surface 7, and the rotary plate 11 flush with the transport road surface 7 is exposed. On the other hand, since the lid plate 23 is fixed to the side plate 71 of the transport road surface 7, it does not move. Therefore, it is not necessary to remove the cover plate 23 one by one to set the slide glass A. Here, the slide glass A moved on the conveyance road surface 7 and placed on the feed plate (short moving conveyance belt) 73 provided at the end of the conveyance road surface 7 has the feed plate 73 close to one end side of the rotating plate 11. It is set on the rotary plate 11 directly by moving until it moves. Thereafter, the elevating member 3 raises and returns the guide frame cylinder 2. Then, after the blood is dropped on the slide glass A from the small hole 23a of the lid plate 23 by the dispensing / dispensing means 63, the centrifugal smearing motor 1b is rotated to perform the centrifugal smearing process.

Thus, it is possible to provide a small-sized apparatus in a small space, not to mention that the transport mechanism has a simple structure.
After the centrifugal smearing process is finished, the guide frame cylinder 2 is lowered again by the elevating member 3, and at the same time, the feed plate 73a of the conveying path surface 7 on the dyeing means side moves close to the other end side of the rotary plate 11. As a result, the slide glass A is transferred to the dyeing means 67.

[0014]

As described above, according to the present invention, since the rotary plate is arranged flush with the conveying road surface and the guide frame cylinder surrounding the rotary plate can be moved up and down by the elevating member, the guide frame cylinder is By moving up and down, the slide glass is extruded and set directly from the conveying path surface to the flush plate. Therefore, the transport mechanism has a simple structure, and it is possible to provide a compact and inexpensive blood sample automatic preparation apparatus in a small space.

[Brief description of drawings]

FIG. 1 is a sectional view showing a main part of an automatic blood sample preparation device according to an embodiment.

FIG. 2 is a side view showing a main part of the automatic blood sample preparation device according to the embodiment.

FIG. 3 is a plan view showing a cover plate of the centrifugal smearing means.

FIG. 4 is an explanatory diagram showing an automatic blood sample preparation device according to an embodiment.

[Explanation of symbols]

 1 Case Main Body 2 Guide Frame 3 Lifting Member 7 Transport Road Surface 11 Rotating Plate

Claims (1)

[Claims] 1. An automatic blood sample preparation in which blood in a blood collection tube is agitated, then blood is dispensed on a slide glass set in a centrifugal smearing means, centrifugally smeared, and stained by a staining means to prepare a blood sample. In the apparatus, the centrifugal smearing means comprises a main body case containing a centrifugal smearing motor, a rotary plate projecting upward from the main body case, the rotary plate being flush with the conveyance path surface, and the rotary plate having an upper part. An automatic blood sample preparation device comprising a guide frame cylinder whose lower part is externally fitted to a main body case, and an elevating member for moving the guide frame cylinder up and down.